ライフサイエンスコーパス: bipolar disorder

1 a viable approach for novel interventions in bipolar disorder.

2 chiatric traits, including schizophrenia and bipolar disorder.

3 st effective mood-stabilizing medications in bipolar disorder.

4 transferable models to predict transition to bipolar disorder.

5 atric conditions including schizophrenia and bipolar disorder.

6 f lithium use during pregnancy in women with bipolar disorder.

7 updating could facilitate risk prediction in bipolar disorder.

8 overactive reward updating in patients with bipolar disorder.

9 egun to shed light on the pathophysiology of bipolar disorder.

10 ctual disability, autism, schizophrenia, and bipolar disorder.

11 ventions for people affected by psychosis or bipolar disorder.

12 rug that is also used to treat migraines and bipolar disorder.

13 ipotent stem cell line cell study related to bipolar disorder.

14 influence schizophrenia and 6.4 K influence bipolar disorder.

15 hium (Li) is a medication long-used to treat bipolar disorder.

16 during reward expectancy in individuals with Bipolar Disorder.

17 PSC studies and literature mining related to bipolar disorder.

18 is of studies of cellular calcium indices in bipolar disorder.

19 n the neurochemistry of major depression and bipolar disorder.

20 nd stimulated free intracellular [Ca(2+)] in bipolar disorder.

21 siological mechanisms with schizophrenia and bipolar disorder.

22 provide potential biological mechanisms for bipolar disorder.

23 schizophrenia, schizoaffective disorder, or bipolar disorder.

24 sed to estimate the clinical trajectory into bipolar disorder.

25 acological interventions aimed at preventing bipolar disorder.

26 ve been implicated in both schizophrenia and bipolar disorder.

27 ors for the development of schizophrenia and bipolar disorder.

28 characterized in schizophrenia and psychotic bipolar disorder.

29 associated with transition from unipolar to bipolar disorder.

30 ular imaging studies of dopamine function in bipolar disorder.

31 eater genetic overlap with schizophrenia and bipolar disorder.

32 rivalry, the other on the pathophysiology of bipolar disorder.

33 a/hypomania and depression that characterize bipolar disorder.

34 schizophrenia, major depressive disorder and bipolar disorder.

35 ared with parental history, particularly for bipolar disorder.

36 mer's disease, autism spectrum disorder, and bipolar disorder.

37 al neurons of subjects with schizophrenia or bipolar disorder.

38 gical agents in the outpatient management of bipolar disorder.

39 a diagnosis of depressive disorder to one of bipolar disorder.

40 e present novel evidence of association with bipolar disorder.

41 tely account for morbidity and mortality in, bipolar disorders.

42 athogenetic, and treatment considerations in bipolar disorders.

43 vironmental exposures on the presentation of bipolar disorders.

44 ogy, mechanisms, screening, and treatment of bipolar disorders.

45 n to improve health outcomes for people with bipolar disorders.

46 otic disorder (2.18, 1.95-2.44; p<0.0001) or bipolar disorder (1.48, 1.24-1.76; p<0.0001), and previo

47 andard deviation increase; p = 8 x 10(-13)), bipolar disorder (1.53[1.44; 1.63]; p = 1 x 10(-43)), sc

48 n deficit hyperactivity disorder, autism and bipolar disorder(2,5).

49 .82]), schizophrenia (2.51 [1.24-5.21]), and bipolar disorder (4.53 [2.41-8.51]) than first contact s

50 as observed among adolescents with past-year bipolar disorder (94.2 [1.69]; P = .004), attention-defi

51 in schizophrenia, major depressive disorder, bipolar disorder, addiction, and anxiety.

52 whose dysregulation is linked to depression, bipolar disorder, addiction, and psychosis.

53 or bipolar disorder predicted progression to bipolar disorder (adjusted hazard ratio for a one-standa

54 tory still strongly predicted progression to bipolar disorder (adjusted hazard ratio=5.02, 95% CI=3.5

55 ers (including major depressive disorder and bipolar disorder) affect 10% to 20% of the population.

56 aracteristics of women at risk of developing bipolar disorder after childbirth, before discussing opp

57 agement of women at risk of transitioning to bipolar disorder after childbirth.

58 anic symptoms in women at risk of developing bipolar disorder after childbirth; however, the potentia

59 ychiatric phenotypes (e.g., r(g) = 0.36 with bipolar disorder and 0.34 with neuroticism) and negative

60 e, educational attainment, ADHD, autism, and bipolar disorder and among de novo variants associated w

61 0% of the causal variants for schizophrenia, bipolar disorder and attention-deficit/hyperactivity dis

62 ution Ala559Val found in subjects with ADHD, bipolar disorder and autism, promotes anomalous DA efflu

63 ite a lack of evidence for their efficacy in bipolar disorder and concerns about increasing the risk

64 eractivity disorder, but is much less so for bipolar disorder and depression.

65 tudies also identified a shared risk SNP for bipolar disorder and educational attainment.

66 al loci from existing GWAS data by analyzing bipolar disorder and epilepsy phenotypes available from

67 icantly lower activation than both psychotic bipolar disorder and healthy groups.

68 ancy should be planned during remission from bipolar disorder and lithium prescribed within the lowes

69 ignificant differences between schizophrenia/bipolar disorder and major depressive disorder were foun

70 The absolute risks of progression to bipolar disorder and psychotic disorders were 7.3% and 1

71 In particular, the horizontal integration of bipolar disorder and schizophrenia and the vertical inte

72 PRSs for bipolar disorder and schizophrenia are associated with r

73 ssion with self-reported MDD, recurrent MDD, bipolar disorder and schizophrenia were 0.79 +/- 0.07, 0

74 d recurrent major depressive disorder (MDD), bipolar disorder and schizophrenia would enhance statist

75 ently detected in psychiatric disorders like bipolar disorder and schizophrenia.

76 ssion with self-reported MDD, recurrent MDD, bipolar disorder and schizophrenia.

77 l and well testable hypotheses especially on bipolar disorder and schizophrenia.

78 MAD1L1 was previously identified in GWASs of bipolar disorder and schizophrenia.

79 he peripartum period, focusing on women with bipolar disorder and their offspring.

80 netic basis of major depressive disorder and bipolar disorder and to highlight disorder-specific asso

81 nce of childhood maltreatment in people with bipolar disorders and the association between childhood

82 The mortality gap between populations with bipolar disorders and the general population is principa

83 schizophrenia spectrum disorder, 37 euthymic bipolar disorder, and 39 healthy control participants),

84 depression (including data from 23andMe) and bipolar disorder, and an additional major depressive dis

85 rison with HCS, we found that schizophrenia, bipolar disorder, and autism spectrum disorder share sim

86 pathways that have been implicated in human bipolar disorder, and changes in intestinal microbiota.

87 was most severe in schizophrenia, milder in bipolar disorder, and indistinguishable from healthy ind

88 polygenic nature of the risk architecture of bipolar disorder, and its overlap with other major neuro

89 PEP3 transcript with risk for schizophrenia, bipolar disorder, and major depression.

90 ed comparison subjects and subjects with SZ, bipolar disorder, and major depressive disorder, and the

91 rder, one associated with suicide attempt in bipolar disorder, and one in the meta-analysis of suicid

92 e networks have been observed in depression, bipolar disorder, and post-traumatic stress disorder.

93 demonstrate MixEHR on MIMIC-III, Mayo Clinic Bipolar Disorder, and Quebec Congenital Heart Disease EH

94 individuals with major depressive disorder, bipolar disorder, and schizophrenia from the Psychiatric

95 nic risk scores (PRSs) for major depression, bipolar disorder, and schizophrenia were generated using

96 on, anxiety, post-traumatic stress disorder, bipolar disorder, and schizophrenia) was 22.1% (95% UI 1

97 ty disorder, post-traumatic stress disorder, bipolar disorder, and schizophrenia.

98 and capabilities of people with psychosis or bipolar disorder, and the staff who support their implem

99 ces toward the goal of better treatments for bipolar disorder, and we outline major challenges for th

100 ising agent for the treatment of people with bipolar disorders, and has antimanic, antidepressant, an

101 ,264 attempters and 5,500 nonattempters with bipolar disorder; and 1,683 attempters and 2,946 nonatte

102 obsessive-compulsive disorder; 5% (3-6) for bipolar disorders; and 4% (3-5) for schizophrenia spectr

103 w that differences between schizophrenia and bipolar disorder are concentrated in excitatory neurons

104 Bipolar disorders are a complex group of severe and chro

105 ly, effective pharmacological treatments for bipolar disorders are not universally available, particu

106 The recent conceptualisation of bipolar disorder as a neuroprogressive illness has highl

107 atric phenotypes including hyperactivity and bipolar disorder as well as epilepsy.

108 onal connectivity, and affect in adults with Bipolar Disorder, as a step toward developing novel inte

109 27) of extended pedigrees heavily loaded for bipolar disorder ascertained from genetically isolated p

110 One bipolar disorder-associated rare variant (M2145T) in TGE

111 ter guide and monitor early interventions in bipolar disorder at-risk youth.

112 f six phenotypes: major depressive disorder, bipolar disorder, attention-deficit/hyperactivity disord

113 Schizophrenia (SCZ), bipolar disorder (BD) and recurrent major depressive dis

114 Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders associ

115 s granule neurons derived from patients with bipolar disorder (BD) as well as a hyperexcitability tha

116 Distinguishing bipolar disorder (BD) from major depressive disorder (MD

117 Bipolar disorder (BD) has been linked to disrupted struc

118 port the notion that 40-60% of patients with bipolar disorder (BD) have neurocognitive deficits.

119 sent study, we analysed whether the risk for bipolar disorder (BD) in BD multiplex families is influe

120 Bipolar disorder (BD) is a chronic affective disorder wi

121 Bipolar disorder (BD) is a chronic, debilitating illness

122 Bipolar disorder (BD) is a common mood disorder characte

123 Bipolar disorder (BD) is a common, highly heritable diso

124 Bipolar disorder (BD) is a highly heritable psychiatric

125 Bipolar disorder (BD) is a serious mood disorder associa

126 Bipolar disorder (BD) is a serious psychiatric illness w

127 Genetic risk for bipolar disorder (BD) is conferred through many common a

128 Bipolar disorder (BD) is one of the most heritable menta

129 Schizophrenia and bipolar disorder (BD) may be disorders of accelerated ag

130 within frontal lobe gray and white matter of bipolar disorder (BD) patients have been consistently re

131 on-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) remains a challenge, mainly due to

132 affective disorder (SAD), 132 with psychotic bipolar disorder (BD)), 315 of their nonpsychotic first-

133 depressive disorder (MDD), 29 subjects with bipolar disorder (BD), and 33 healthy controls who perfo

134 Schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MD

135 isorders (MPDs), such as schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MD

136 rs, such as major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SZ), as well a

137 abolites in major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SZ).

138 Lithium is a first-line medication for bipolar disorder (BD), but only one in three patients re

139 leotide polymorphisms (SNPs) associated with bipolar disorder (BD), but what the causal variants are

140 disorders: autism spectrum condition (ASC), bipolar disorder (BD), major depressive disorder (MDD),

141 1 in every 50 to 100 people is affected with bipolar disorder (BD), making this disease a major econo

142 ations with Major Depressive Disorder (MDD), Bipolar Disorder (BD), Schizophrenia, anxiety, and Post

143 Lithium (Li) is a first-line treatment for bipolar disorder (BD).

144 s in states, and the impact of treatments in bipolar disorder (BD).

145 their relevance for schizophrenia (SCZ) and bipolar disorder (BD).

146 order (OBP) are at increased risk to develop bipolar disorder (BD).

147 -cortical circuits in schizophrenia (SZ) and bipolar disorder (BD).

148 s from patients with schizophrenia (SCZ) and bipolar disorder (BD).

149 ion of the kynurenine pathway (KP) occurs in bipolar disorder (BD).

150 opathological findings have been reported in bipolar disorder (BD).

151 o lie at the heart of the pathophysiology of bipolar disorder (BD); however, diffusion tensor imaging

152 mains the gold standard for the treatment of bipolar disorder (BD); however, its use has declined ove

153 Bipolar disorders (BDs) are among the leading causes of

154 irs affected with schizophrenia (SCZ) and/or bipolar disorder (BIP) (i.e., dual-affected pairs).

155 ric Genomics Consortium-schizophrenia (SCZ), bipolar disorder (BIP), major depression (MD), attention

156 In patients with schizophrenia and bipolar disorder, both alterations in cerebral connectiv

157 free intracellular [Ca(2+)] is increased in bipolar disorder, both in platelets and in lymphocytes.

158 onological ages (r = 0.88/0.91), elevated in bipolar disorder (BP) and schizophrenia (SCZ), and uncha

159 ool to differentiate schizophrenia (SZ) from bipolar disorder (BP) even after balancing patients for

160 tal illnesses such as schizophrenia (SZ) and bipolar disorder (BP) frequently accompany metabolic con

161 elucidate the underlying pathophysiology of bipolar disorder (BP).

162 l attainment-the relationship is positive in bipolar disorder but negative in major depressive disord

163 ove health care for people with psychosis or bipolar disorder, but despite their potential, integrati

164 disorder is considered as a severe course of bipolar disorder, but it is unclear whether rapid cyclin

165 tic studies of major depressive disorder and bipolar disorder can be combined effectively to enable t

166 Lithium, mainstay treatment for bipolar disorder, causes nephrogenic diabetes insipidus

167 tive lack of habituation among patients with bipolar disorders compared with others.

168 Genetic correlations revealed that type 2 bipolar disorder correlates strongly with recurrent and

169 in mental disorders, such as schizophrenia, bipolar disorder, depression, anxiety disorders, and att

170 ciation of psychiatric diagnoses (psychosis, bipolar disorder, depression, anxiety, and posttraumatic

171 Antidepressants are widely prescribed for bipolar disorders despite a paucity of compelling eviden

172 at least one diagnostic code reflective of a bipolar disorder diagnosis within 3 months of index anti

173 Schizophrenia and bipolar disorder do not appear to share similar mitochon

174 Undiagnosed bipolar disorder early in the disease course is associat

175 treatment and a more complex presentation of bipolar disorder (eg, one including suicidality) highlig

176 lcium signalling has long been implicated in bipolar disorder, especially by reports of altered intra

177 gamma-aminobutyric acid (GABA) mediated) and bipolar disorder (excitatory).

178 etermine whether schizophrenia and psychotic bipolar disorder exhibit similar abnormalities in WM-rel

179 dy of the corpus callosum; schizophrenia and bipolar disorder featured comparable changes in the limb

180 DEGs in the bipolar disorder group were not enriched for functional

181 Both schizophrenia and psychotic bipolar disorder groups showed encoding- and maintenance

182 Bipolar disorder has a high heritability (approximately

183 reased mortality and significant impairment, bipolar disorder has persisted in the population with a

184 jor mental illness such as schizophrenia and bipolar disorder have co-morbid physical conditions, sug

185 Pharmacological options for treating bipolar disorder have increased over the past 20 years,

186 technique that may be a useful treatment for Bipolar Disorder if targeted to neural regions implicate

187 Bipolar disorder in individuals at familial risk typical

188 rs sought to describe the emergent course of bipolar disorder in offspring of affected parents subgro

189 articipant in the 30 mg/kg opicinumab group, bipolar disorder in one (1%) participant in the 100 mg/k

190 idepressants occurred in 47.0% of visits for bipolar disorder in the 1997-2000 period and 57.5% in th

191 abilizers decreased from 62.3% of visits for bipolar disorder in the 1997-2000 period to 26.4% in the

192 creasing from 12.4% of outpatient visits for bipolar disorder in the 1997-2000 period to 51.4% in the

193 up, and 16 deaths (3%) and one (<1%) case of bipolar disorder in the control group were recorded.

194 1%) psychotic illness, and one (<1%) case of bipolar disorder in the intervention group, and 16 death

195 ood stabilizers are better for patients with bipolar disorder in the maintenance phase.

196 s confer advantages, which serve to maintain bipolar disorder in the population.

197 targeted interventions in the prevention of bipolar disorder in women who have recently given birth.

198 association with risk for schizophrenia and bipolar disorder, increased expression of a ST3GAL3 tran

199 Cells from bipolar disorder individuals also show an enhanced [Ca(2

200 differed between schizophrenia and psychotic bipolar disorder; individuals with schizophrenia showed

201 Bipolar disorder is a chronic neuropsychiatric condition

202 Bipolar disorder is a chronic relapsing condition in whi

203 Bipolar disorder is a heritable disorder characterized b

204 Bipolar disorder is a highly heritable illness, associat

205 Bipolar disorder is a highly heritable psychiatric disor

206 Bipolar disorder is a lifelong mood disorder characteriz

207 Moreover, antidepressant prescription in bipolar disorder is associated, in many cases, with mood

208 Rapid cycling (RC) bipolar disorder is considered as a severe course of bip

209 Bipolar Disorder is costly and debilitating, and many tr

210 der, but it is unclear whether rapid cycling bipolar disorder is linked to highly altered membrane ph

211 he therapeutic window for lithium therapy of bipolar disorder is very narrow, and more frequent monit

212 Although the pathogenesis of bipolar disorders is unknown, implicated processes inclu

213 ACKGROUNDAlthough mania is characteristic of bipolar disorder, it can also occur following focal brai

214 ychosis and participants with schizophrenia, bipolar disorder, major depressive disorder, and obsessi

215 y disorder (ADHD), autism spectrum disorder, bipolar disorder, major depressive disorder, and schizop

216 sorders, including autism spectrum disorder, bipolar disorder, major depressive disorder, and schizop

217 for 6 psychiatric disorders (schizophrenia, bipolar disorder, major depressive disorder, cross disor

218 s and clinical features in schizophrenia and bipolar disorder may be linked via mitochondrial dysfunc

219 While schizophrenia and bipolar disorder may have similar pathological character

220 Bipolar disorder may thus be better conceptualized as a

221 rential volume alterations in schizophrenia, bipolar disorder, multiple sclerosis, mild cognitive imp

222 ) and patients with schizophrenia (N = 696), bipolar disorder (N = 211), autism spectrum disorder (N

223 wed significant evidence of association with bipolar disorder (n = 24) to map QTL influencing regiona

224 t was assessed pre and post scan in remitted Bipolar Disorder (n = 27) and age/gender-matched healthy

225 ve cohort mainly consisting of subjects with bipolar disorder (n = 359).

226 e either healthy (n = 110) or diagnosed with bipolar disorder (n = 40), attention-deficit/hyperactivi

227 m the prefrontal cortex in schizophrenia and bipolar disorder (n = 55 cases and 27 controls).

228 n associations = 499; n unique genes = 275), bipolar disorder (n associations = 17; n unique genes =

229 ia or other psychotic illness (n=343 [65%]), bipolar disorder (n=115 [22%]), and schizoaffective diso

230 s (Schizophrenia spectrum, n = 79; Psychotic Bipolar disorder, n = 61) and matched healthy controls (

231 s outcomes, we explored depressive symptoms, bipolar disorder, neuroticism, loneliness, and mental he

232 sive disorder, generalised anxiety disorder, bipolar disorder, neuroticism, mood instability and risk

233 ed by more schooling years is an artefact of bipolar disorder - not education.

234 Offspring of parents with bipolar disorder (OBP) are at increased risk to develop

235 tween polygenic liability and progression to bipolar disorder or psychotic disorders among individual

236 are associated with risk for progression to bipolar disorder or psychotic disorders, respectively, a

237 olled study, we recruited heavy smokers with bipolar disorder or schizophrenia from 16 primary care a

238 of schizophrenia, schizoaffective disorder, bipolar disorder, or other psychotic illness according t

239 al changes have occurred in the treatment of bipolar disorder over the past 20 years, with second-gen

240 isk for schizophrenia (P <= 1 x 10(-10)) and bipolar disorder (P <= 0.005).

241 confirm that chronic use in a sample of 384 bipolar disorder patients is associated with longer telo

242 = 46), schizophrenia patients (n = 25), and bipolar disorder patients with (n = 17) and without (n =

243 threshold compared with control subjects and bipolar disorder patients without psychotic features.

244 Comparing between schizophrenia spectrum and bipolar disorder patients, the models for positive sympt

245 Studies of patients with pediatric bipolar disorder (PBD) can help elucidate the developmen

246 anxiety, psychosis, schizophrenia, mania, or bipolar disorder, personality disorder, substance use, a

247 riant data were available, schizophrenia and bipolar disorder polygenic risk were significantly overt

248 ustment for the other PRSs, only the PRS for bipolar disorder predicted progression to bipolar disord

249 ng subtypes of major depressive disorder and bipolar disorder provides evidence for a genetic mood di

250 nxiety (HR = 6.87, 95%CI 3.97-11.90); mania, bipolar disorder, psychosis, or schizophrenia (HR = 2.70

251 mental health outcomes (depression, anxiety, bipolar disorder, psychosis, or suicide).

252 t in major depressive disorder (R(2)=0.25%), bipolar disorder (R(2)=0.24%), and schizophrenia (R(2)=0

253 lysis of major depression than from that for bipolar disorder reached genome-wide significance.

254 ilar to the differences in schizophrenia and bipolar disorder relative to HCS.

255 ular mechanisms underlying schizophrenia and bipolar disorder remain poorly understood.

256 Currently, the pathophysiology of bipolar disorder remains elusive, but treatment with lit

257 , the effective treatment, and prevention of bipolar disorder represents an area of significant unmet

258 gher prevalence of inguinal hernia and mania/bipolar disorder respectively in male duplication carrie

259 ndelian randomization of schooling years and bipolar disorder reveals that the increased risk of schi

260 ers of future affective lability in youth at bipolar disorder risk from the Pittsburgh Bipolar Offspr

261 step toward identifying objective markers of bipolar disorder risk, to provide neural targets to bett

262 This is supported by our bipolar disorder sample, which shows that polygenic risk

263 ntion deficit/hyperactivity disorder [ADHD], bipolar disorder, schizophrenia, alcohol dependence diso

264 nked to neuropsychiatric diseases, including bipolar disorder, schizophrenia, and autism.

265 ic overlaps with psychiatric conditions like bipolar disorder, schizophrenia, and cross-disorder susc

266 abnormalities in major depressive disorder, bipolar disorder, schizophrenia, and obsessive-compulsiv

267 sorders including major depressive disorder, bipolar disorder, schizophrenia, obsessive-compulsive di

268 s (ICD9/10CM) codes for anxiety, depression, bipolar disorder, schizophrenia, or other psychotic diso

269 order, major depressive disorder, a combined bipolar disorder-schizophrenia phenotype, and a broader

270 valence for severe disorders (schizophrenia, bipolar disorder, severe depression, severe anxiety, and

271 Bipolar disorders share genetic risk alleles with other

272 Only bipolar disorder shows consistent results, with similar

273 oate (VPA) has been used in the treatment of bipolar disorder since the 1990s.

274 Bipolar disorders substantially reduce psychosocial func

275 ied the ANK3 W1989R variant in a family with bipolar disorder, suggesting a potential role of this va

276 , intracellular basal [Ca(2+)] was higher in bipolar disorder than in unipolar depression, but not si

277 GWAS statistics from genetically correlated bipolar disorder, the effect size of SNP genotypes on ge

278 ogy of first-episode mania in the context of bipolar disorder, the natural history of mania (with an

279 direct comparison between schizophrenia and bipolar disorder, there were no significant differences.

280 traits, ranging from 2.44% h(2) decrease for bipolar disorder to 14.2% h(2) decrease for Tourette syn

281 ustained effects on mood in individuals with Bipolar Disorder, to guide new treatment developments fo

282 atric disorders-autism spectrum disorder and bipolar disorder-to show that it is applicable to develo

283 hiatric conditions, including schizophrenia, bipolar disorder, Tourette's syndrome, dementia, alcohol

284 The cumulative incidence of bipolar disorder was 24.5%, and the median age at onset

285 The best-fit model of emerging bipolar disorder was a progressive sequence from nonspec

286 Parent bipolar disorder was confirmed by the best-estimate proc

287 ressants among psychiatrist visits for which bipolar disorder was listed among the primary diagnoses.

288 l and genetic overlap between depression and bipolar disorder, we investigated whether a polygenic su

289 isease Study estimates for schizophrenia and bipolar disorder were applied in these estimates for con

290 enriched for antipsychotics, while those for bipolar disorder were enriched for both antipsychotics a

291 with a history of psychosis or rapid-cycling bipolar disorder were excluded.

292 Among women, only psychosis and bipolar disorder were predictive of both CVD events and

293 en, we found that depression, psychosis, and bipolar disorder were predictive of both CVD events and

294 Li activity on snoRNA levels may pertain to bipolar disorders while Li modification of protein codin

295 therwise specified and no prior diagnosis of bipolar disorder, who received at least one of the nine

296 = 49), schizoaffective disorder (n = 37), or bipolar disorder with psychosis (n = 72), and identified

297 y psychotic disorder or affective psychosis (bipolar disorder with psychosis and schizophrenia or sch

298 Patients with psychosis (schizophrenia and bipolar disorder with psychotic features) had an elevate

299 (1.36%) subsequently received a diagnosis of bipolar disorder within 3 months.

300 rder without psychosis (unipolar depression, bipolar disorder without psychosis), and 608 demographic