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1          Randomisation was done centrally in blocks of 12, and stratified by trial centre, general pr
2  assigned patients to one of three groups in blocks of 15 to receive placebo (normal saline), low-dos
3 ts were randomized (1:1) without blinding in blocks of 24.
4 central web-based data capture system (mixed blocks of 3 and 6), and stratified by study site.
5 /s(2)) in a pseudo-randomised order across 4 blocks of 30 trials in both vision conditions, received
6                          Genetic ablation or blocking of 4-1BBL signaling by Ab or 4-1BB-Fc alleviate
7 We performed a randomized (at patient level, blocks of 4), controlled non-inferiority study among chi
8 hburg, NJ), with stratification by center in blocks of 6.
9 cal communication and providing the building block of a future large-scale quantum network.
10  energy efficiency is found to be limited by blocking of a phosphate anion, while in alkali hydroxide
11                      Fibers are the building blocks of a broad spectrum of products from textiles to
12        These results constitute the building blocks of a dedicated local memory per quantum-dot spin
13 ubjects (male and female) completed multiple blocks of a reinforcement learning task that contained a
14 of the boulders that constitute the building blocks of a rubble-pile asteroid.
15                                 The building blocks of a virus derived from de novo biosynthesis duri
16 states are locally well-segregated yet the B blocks of ABA amphiphiles are significantly less stretch
17                                We found that blocking of abasic (AP) sites abolishes higher survival
18 r fault system that separates regional-scale blocks of accreted, continental materials in southern Ta
19  at 2.55 and 2.70 angstrom revealed a direct block of ACE2 attachment.
20 ase in synaptic strength following a chronic block of activity.
21 iation and the depotentiation resulting from block of adenosine transport.
22 rve little functional diversity unless large blocks of adjacent natural habitat are protected, consis
23 eased in the presence of SRFA as a result of blocking of AgNP surface sites through either steric or
24 r whether neurexins are fundamental building blocks of all synapses with similar overall functions or
25 alization for IFITM1 function, we identified blocks of amino acids in the conserved intracellular loo
26               Here, the fundamental building blocks of an FHE system, printed sensors and circuits, t
27  neurons as male Long-Evans rats performed 6 blocks of an object discrimination task in sets of 15 tr
28 eparates relatively undeformed, microcracked blocks of anorthosite.
29 f systems science is to uncover the building blocks of any biological network to decipher how cellula
30 7)Sm-(142-143)Nd data reveal that this large block of Archean crust formed by reworking of much older
31          In addition, CRISPRi/dCas9-mediated blocking of Ash2l-binding motifs at these super-enhancer
32 a major determinant of an interferon-induced block of ASLV release.
33 ogical mechanism, we identified H1N1-induced blocking of autophagosome formation and inhibition of au
34  "looping" conformations are prevalent for A blocks of BAB amphiphiles.
35 in attenuated FMD of the femoral artery, and blocking of beta1 integrin function did not further decr
36                         In contrast, in vivo blocking of beta1 integrins or alpha4 integrins did not
37 alized collagen fibril is the basic building block of bone, and is commonly pictured as a parallel ar
38                            When the building blocks of both cages were present during self-assembly,
39 lity of the assemblies that are the building blocks of both micellar and chromonic lyotropic liquid c
40 ghts into molecular convergence and building blocks of CAM and will facilitate CAM-into-C3 photosynth
41 cytosolic acetyl-CoA, a fundamental building block of carbon metabolism in eukaryotes.
42    Together, the current study suggests that blocking of CB1 ameliorates Diet-Induced Obesity and met
43 hanges was restored to control levels by the blocking of CCN2 signaling in HRHF-Rest/FG-3019 rats, as
44 ble for SIV infection of SM in vivo and that blocking of CCR5 does not prevent ex vivo infection of p
45                    We further found that the block of CD74 degradation in CatS(-/-) B cells is incomp
46                              As the building blocks of chromatin, histones are central to establish a
47                        As the basic building blocks of chromatin, nucleosomes play a key role in dict
48 omputational errors, constitute the building blocks of complete and scalable quantum error correction
49        Although these PAHs resemble building blocks of complex carbonaceous nanostructures, their fun
50         These elements serve as the building blocks of complex structures discussed in cognitive psyc
51          Ion channel models are the building blocks of computational neuron models.
52                                     Building blocks of concern to the field of crystallization are th
53              The alignment is arranged in 17 blocks of conserved regions and unaligned blocks in betw
54 tate of island arc rocks, which are building blocks of continental crust.
55                  We demonstrate that in vivo blocking of CXCL1 and CXCL2 can significantly reduce the
56                                     Finally, blocking of CXCR6 with its ligand CXCL16 significantly i
57  to distil multiple signatures from the same block of data, thus reducing the statistical fluctuation
58 The synthetic strategy of combining building blocks of defined stereochemistry (here overhand knots o
59 es in functionality of CD4 T cells following blocking of different inhibitory receptors, and we confi
60 strength, in response to presentations (64 s blocks) of different levels of image contrast (3%, 12.5%
61 held belief that AML results from a complete block of differentiation of the hematopoietic stem cell,
62 abdomyosarcoma (ERMS) and contributes to the block of differentiation.
63                                              Blocking of Dll4 promotes the entrance of new hemogenic
64                                 The building blocks of DNA, dNTPs, can be produced de novo or can be
65 nsable for producing the nucleotide building blocks of DNA, RNA, and cGMP and that cancer cells posse
66 trast, 1 h after induction of depolarization block of dopamine neurons by acute haloperidol treatment
67  in the presence of Mcm10 the CMG melts long blocks of dsDNA while it encircles dsDNA.
68 ges in the Ca(2+) transients produced by the block of each individual VGCCs, of A-type VGKCs and of S
69 y interbred, based on the detection of large blocks of each ancestry across each chromosome.
70 affeensis, and protective mechanisms involve blocking of ehrlichial attachment or complement and Fcga
71 vated influenza vaccine or saline placebo in blocks of eight, stratified by gestational age at enrolm
72 cations in approximately a 1:1:1:1 ratio, in blocks of eight, to a consecutive series of numbers.
73                                Gene-specific blocking of EJC deposition by antisense oligonucleotides
74 (3)(OH)), which are the fundamental building blocks of enamel, comprise two nanometric layers enriche
75  perivascular homing paths, leading to rapid block of entry.
76  nonsilicified cell walls prepared as a flat block of epoxy-embedded awns of wheat (Triticum turgidum
77 s of corner-sharing octahedra "insulated" by blocks of face-sharing octahedra.
78                                              Blocking of FDC secretion of IFN-alpha restored B cell t
79 hedule was computer generated, used permuted blocks of four and six, and was stratified by participat
80 ients older than 50 years to groups (1:1) in blocks of four by use of an interactive web portal; thes
81 olled patients were randomly assigned 1:1 in blocks of four per stratum to receive pembrolizumab 200
82 ced disease, were randomly assigned (1:1) in blocks of four per stratum with an interactive voice-res
83  or EUC combined with CAP, in randomly sized blocks of four to six, stratified by primary health cent
84     Patients were randomly assigned (1:1) in blocks of four with a computer-generated randomisation s
85 mefantrine group or AQ-13 group by permuting blocks of four with a random number generator.
86 idomide using a permutated blocked design in blocks of four, stratified according to age, number of p
87 nerated randomisation software with permuted blocks of four.
88 taining chemotherapy regimen, using permuted blocks of four.
89 ass based oscillators to be used as building block of future mechanical metamaterials, leading to a n
90                    These are common building blocks of general adaptive behaviors.
91                                        Thus, blocking of gK binding to SPP may be a useful tool to co
92 of its substrate glutathione or the building blocks of glutathione (such as cysteine), can trigger fe
93   Mannose is one of the fundamental building blocks of glycans in many biological membranes.
94      Our chromatin model demonstrates that a block of H3K9 methylations in the epigenetic sequence de
95 tion of enzymes that synthesize the building blocks of HA, UDP-Glucuronic acid and UDP-N-Acetyl-Gluco
96 cribe a second function of PtDd, namely, the blocking of HD5.
97 dle-income countries, using the six building blocks of health systems described by WHO (information a
98           Connexin proteins are the building blocks of hemichannels, which dock further between adjac
99 l, high pH potentiated the fentanyl-mediated block of hERG channels, with an IC(50) at pH 8.4 being 7
100 and currents (e.g., 10.4-fold for dofetilide block of hERG current and 4-fold for mexiletine block of
101  hypokalemia, and alkalosis can increase the block of hERG current by fentanyl, potentially increasin
102 ic assessment of the potency of kappaM-RIIIJ block of heteromeric K(+) channel-mediated currents in h
103                               The 2-5 minute blocks of high-reward trials led to ramp-like decreases
104 -miR-128 partly neutralizes the IFN-mediated block of HIV-1.
105 -miR-128 partly neutralizes the IFN-mediated block of HIV-1.
106 ck of hERG current and 4-fold for mexiletine block of hNav1.5 current).
107         Objects are the fundamental building blocks of how we create a representation of the external
108                                         Only blocking of HSPA proteins using pan-HSPA inhibitors, VER
109 e starting to reveal aspects of the building blocks of human memory at the single-cell level.
110 ic circumstances exacerbate fentanyl-induced block of I(hERG) Our results show that chronic hypoxia o
111                   However, fentanyl-mediated block of I(hERG) was voltage dependent.
112                              Pharmacological block of IA completely abolished rebound delays and, imp
113          CCR10(+) ILC2 depletion, as well as blocking of IFN-gamma activity, exacerbates airway hyper
114 -alpha/beta-receptor (IFNAR), as Ab-mediated blocking of IFNAR1 prevented the production of NO.
115                                     Combined block of IK1 and IKr was effective in terminating re-ent
116 g feedforward and recurrent networks made of blocks of imprimitivity.
117 and (4) derive the prediction that effective block of INaP by low concentration tetrodotoxin will sto
118 res that allow us to avoid iterating through blocks of incomplete matches.
119 ly depleted from the MZ by antibody-mediated blocking of integrin function.
120                                              Blocking of interferon-gamma (IFNgamma) reduced the tran
121 uced by Sendai virus argue against an active block of IRF3 activation by the Brazilian strain of ZIKV
122 AMT binding in a channel results in complete block of its proton current.
123 Periplaneta americana Our data showed that a block of JH biosynthesis or JH action arrested vitelloge
124 d that triads of relationships, the building blocks of larger social structures, have a propensity to
125  have identified a mutant that overcomes the block of lateral root (LR) formation under osmotic stres
126 hich results in an unusual voltage-dependent block of leak channels belonging to the TASK subfamily.
127 whole organisms at the level of the building block of life: the cell.
128 facilitated production of molecular building blocks of life, but its impact on self-assembly and comp
129 challenge for natural polypeptides, building blocks of life, which are fragile and difficult to handl
130 production of monolignols, the main building blocks of lignin.
131                              Given the small blocks of linkage disequilibrium in Drosophila, we obtai
132 ve attention constitutes one of the building blocks of listening in natural environments, its neural
133 bove 565 nm (orange & red) and that targeted blocking of lower wavebands (up to 430 nm) using light r
134                            The RvE1 and RvD1 block of LTB4-stimulated increase in [Ca(2+)](i) was als
135 lanetary bodies, being an essential building block of major mineral phases in the crust and mantle of
136                                              Blocking of matrix metalloproteinases or tyrosine kinase
137  chemical elements and molecules as building blocks of matter has been the central goal and challenge
138                       Atoms are the building blocks of matter that make up the world.
139 f chemoselectively modified peptide building blocks of medium-to-large size, conjugation of these sub
140            Such reductant acts as a building block of mesostructured frameworks and reduces Ti(4+) in
141 pha- and beta-tubulin proteins, the building blocks of microtubule arrays.
142 ible detyrosination of tubulin, the building block of microtubules, is crucial for neuronal physiolog
143 ulin heterodimer is the fundamental building block of microtubules, making it central to several cell
144     Fundamental to such systems are building blocks of "mini-homeostasis": feedback loops in which on
145                                              Block of mito-Ca(2+) uptake in mature cells depresses pr
146 istable systems are one of the main building blocks of more complex behaviors such as oscillations, m
147 tions, which includes their role as building blocks of more complex lipids (e.g., glycerophospholipid
148 otein O-glycosylation, induces developmental blocks of mouse B cells.
149 ild-Pugh class (B vs C) and restricted using blocks of multiples of three.
150                                Additionally, blocking of N uptake and therefore plant biomass, and pr
151                                 In addition, block of Na(V)1.2 may complement the anticonvulsant acti
152 )1.6 inhibitors, which also displayed potent block of Na(V)1.2.
153  of nonproteinogenic amino acids as building blocks of natural products and are attractive biocatalys
154 rocessing, and advocate that pharmacological block of NaV 1.7 alone in the viscera may be insufficien
155 s, we presented participants with successive blocks of near-threshold tasks involving subjective repo
156 eHMM, a new computational method to identify blocks of neighboring SNPs that share similar allele spe
157 of the related signaling pathways would make blocking of neonatal immune tolerance to retroviruses an
158 Network motifs are often called the building blocks of networks.
159 king of individual animals revealed that the blocking of neutrophil recruitment leads to rapid mortal
160  cell death, inhibition of autophagy and the blocking of new infections.
161 r-generated randomisation list with permuted blocks of nine.
162 ry subunit of NMDAR or acute pharmacological block of NMDAR prevents experience-dependent homeostatic
163                  Immunostaining revealed the blocking of nuclear translocation of p65 in gingival fib
164  of synthesis of phospholipids, the building blocks of organelle membranes, or remodeling of their fa
165       Tubular epithelia are a basic building block of organs and a common site of cancer occurrence(1
166                   Carbon, the basic building block of our universe, enjoys a vast number of allotropi
167 or specific episodic events are the building blocks of our autobiographical memory.
168           We describe here the main building blocks of our tool as well as an evaluation of the retri
169 elf-assembly helped to identify the building blocks of OVT nanofibrils.
170 marrow derived leukocytes or pharmacological block of P2X7Rs primarily outside of the central nervous
171 oval of extracellular ATP or pharmacological blocking of P2Y11 receptors.
172 pheral nociceptors, the fundamental building blocks of pain transmission.
173                 Here, we show that selective block of Panx1 in single postsynaptic hippocampal CA1 ne
174                                              Blocking of PCP-dependent elongation disrupts the shapin
175 ility in clinical applications of conduction block of peripheral nerve hyperactivity, for example in
176 y point into various aryl thioether building blocks of pharmaceutical interest.
177 f cellulose fibers, one of the main building blocks of plant cell walls, has yielded unique families
178          In addition, the MKL1-actin imposed block of pluripotency can be bypassed, at least partiall
179 ion for 29/31KR Gag-YFP, suggesting that the blocking of PM binding is more readily reversed than tha
180                             More substantial blocking of Pol II translocation can be caused by other
181 rid wheat seed relies on male sterility, the blocking of pollen production, to prevent self-pollinati
182 tion of glutarate, an attractive C5 building block of polyesters and polyamides.
183 particles assembled with amphiphilic polymer blocks of polyethyleneglycol (PEG) and biodegradable pol
184 arge end point, which is consistent with the blocking of pores in the carbon host matrix.
185                                    Moreover, blocking of potassium efflux improved the mitochondrial
186 data set from an experiment with three mixed blocks of pro- and antisaccade trials.
187 ing 363 epigenetic regulators and identified Block of Proliferation 1 (BOP1) as a factor the loss of
188                        The nucleolar protein block of proliferation 1 (BOP1) is associated with multi
189 otypes (MIC and growth rate with OTC), while blocking of protein synthesis using low concentrations o
190 immune cells and brain, apparently involving blocking of protein-protein interactions that initiate T
191  work may provide new insight about building blocks of protein nanofibrils and impact of polyols on p
192             Domains are the primary building blocks of protein structure and function.
193                 Amino acids are the building blocks of proteins, and our results are consistent with
194 ained spread and, in turn, can be a building block of public health decision making.
195 of a secure schedule generated with permuted blocks of randomly varying block sizes.
196 tary processes in a picture naming task with blocks of semantically heterogeneous (HET) or HOM stimul
197 ion, we employ the assay to measure receptor blocking of sera from SARS-CoV-2-infected patients.
198  directly, we can rescue the pharmacological block of Shaw and Shal, restore the firing rhythm, and t
199 randomly assigned the microfinance groups in blocks of six to receive either the intervention (ie, th
200 dary care were randomly allocated (3:3:1) in blocks of six using a computer-based random number table
201 a computer generated randomisation sequence (blocks of six) to receive either two intranasal doses (0
202 label, non-inferiority, randomised (1:1 with blocks of six), multicentre, phase 3 clinical trial comp
203   Patients were randomly assigned (1:1:1) in blocks of six, stratified by planned platinum, using an
204 by use of computer-generated random permuted blocks of six, to either cediranib (30 mg orally, once d
205 puter-generated randomisation code, in fixed blocks of six, to either CVT-301 60 mg, CVT-301 84 mg, o
206 or direct laryngoscopy using random permuted blocks of size 2, 4, and 6, and stratified by site and c
207 equence was computer generated with permuted blocks of size 4 and 6 and stratified by site.
208 pilot randomized trial (1:1 allocation using blocks of size 6) in which patients were randomized to r
209 ents were randomised using randomly permuted blocks of size four and six and stratified by site, with
210 isation at nurse level with randomly ordered blocks of size four, six, and eight.
211 andomly assigned 1:1 using randomly permuted blocks of size two, four, or six to receive six intraven
212 fied blocked randomisation (randomly ordered blocks of sizes three and six, stratified by site and se
213 y of these drugs is thought to be due to the block of sodium channels on excitatory neurons, primaril
214                        'Mesoatomic' building blocks of soft-matter crystals consist of groups of mole
215       They can be thought of as the building blocks of solar structures.
216 nced in low-quality kidneys and suggest that blocking of some targets might improve transplant outcom
217 l microstates are thought to be the building blocks of spontaneous consciousness.
218 he compartment occupied by inner hydrophilic blocks of star-like diblock copolymers imparts in situ f
219 rm bandit task that had randomly interleaved blocks of stimulus-based and action-based reinforcement
220 phate, forming a cytosolic bypass around the block of stromal triose phosphate isomerase.
221 claims that valence and arousal are building blocks of subjective experience.
222                                 The building block of such an assembly is a C(3)-symmetric monomer, c
223       Here we present two essential building blocks of such a SAW-driven quantum circuit.
224 se guest-host structures become the building blocks of superconducting compounds at extreme condition
225             This model examines the building blocks of surface coverage assays, including heterogeneo
226  their genetic elimination causes a complete block of synaptic transmission.
227 anosomatid parasites beyond being a building block of T(SH)(2), most of its functions are replaced by
228  subjects while they performed several short blocks of tasks and reported on which task they think th
229 ed by a non-study statistician with sequence blocks of ten that were stratified by study clinic.
230 biting slow conduction and ectopic activity, block of TGF-beta1 signaling completely abolished both a
231 lectrode voltage clamp showed dose-dependent block of the AQP1 ion current by 5HMF (IC(50) 0.43 mM),
232 hich has a potential to disrupt drug-induced block of the channel.
233 echanically induced myotonia and to evaluate block of the channels involved as a novel approach to th
234       Frequency conversion forms an integral block of the electronic circuits used in various applica
235           Quantum entanglement is a building block of the entangled quantum networks of the quantum I
236 ection which, we found, may be mediated by a block of the hair cell's mechanoelectrical transducer (M
237 entially captured completely by only a 3 x 3 block of the Hessian, although these values must correct
238                                     LTB4 and block of the LTB4-stimulated increase in [Ca(2+)](i) by
239 and tissue antigens, as well as the building block of the marine algal galactan lambda-carrageenan.
240 ever, this element was not included in the p-block of the periodic table until more recently.
241 is a common side effect caused by unintended block of the promiscuous drug target human ether-a-go-go
242 ELISA) based and can measure competition and blocking of the ACE2 receptor to the SARS-CoV-2 spike pr
243                                    A similar blocking of the barotropic component may occur in other
244 depletion of TAMs, reprograming of TAMs, and blocking of the CD47-SIRPalpha pathway, are discussed.
245  in cytokine-induced ILC2 activation because blocking of the COX-1/2 or HPGDS enzymes or the CRTH2 re
246 n that prevent premature activation: (1) cis blocking of the D4 dimerization interface and (2) trans
247                      The data also show that blocking of the Galpha13 protein from binding to the cyt
248  and Bovine serum albumin (BSA) was used for blocking of the non-specific binding sites.
249                        Furthermore, specific blocking of the proximal 3'UTR reduced surface expressio
250                                              Blocking of the purine-synthesis- did not affect resista
251 ith the ACE2 binding surface, explaining the blocking of the RBD-ACE2 interaction.
252  ex vivo intestinal tissue sections, despite blocking of the receptor with transferrin (Tf) noncompet
253                                          The blocking of the Y. pseudotuberculosis-CD209 interactions
254 (H(2) TAPP) and Fe(II) were used as building blocks of the aerogel, which was later heat-treated at 6
255          Astrocytes are fundamental building blocks of the central nervous system.
256  but muscle synergies that form the building blocks of the complex behavioral repertoire of these ani
257 ed genes, metabolic energy, and the building blocks of the endomembrane system.
258 telets not only serve in concert as building blocks of the hemostatic plug but also act individually
259                             The key building blocks of the planets may be represented by chondrules,
260 de polymorphisms (SNPs) representing linkage blocks of the SLC2A14 gene.Both GLUT14 isoforms mediated
261 ains and subdomains are fundamental building blocks of the three-dimensional genome.
262  receptors (RTKs), consistent with a partial block of their trafficking from the ER to the Golgi.
263  by their ubiquitination and diminished by a block of their ubiquitination.
264                                  After three blocks of therapy, patients with high minimal residual d
265  and this suppression was most likely due to blocking of these epitopes by stem-specific antibodies i
266 us here on the repeating structural building blocks of these antennae in Saturniid moths.
267                                              Blocks of these hydrogels are then adhered into a struct
268                                              Block of THIK-1 function also inhibits release of the pr
269 he cellular circadian clock work as building blocks of those properties.
270  randomly assigned (1:1:1 in random permuted blocks of three or six) to receive standard shunts (stan
271                                   Removal or blocking of Thy-1, or blocking Thy-1-beta integrin inter
272                           We defined 147,888 blocks of tightly coupled CpG sites, called methylation
273                         We aggregated hourly blocks of time, using previously defined time intervals
274                Single cells are the building blocks of tissue systems that determine organ phenotypes
275                                         When blocking of TLR4 signaling after injury was delayed, how
276 eHMM identified thousands of allele specific blocks of transcription in both coding and non-coding ge
277 een in transduction mutants were mimicked by block of transduction channels of cochlear explants in c
278    This is sufficient to overcome the steric block of transmission of conformational changes within E
279                                  In separate block of trials, participants indicate whether two seque
280  location to attend before the start of each block of trials, to exclude potential visual cue-specifi
281  the timescale of evidence evaluation across blocks of trials depending on context [1].
282 ale rats during a decision-making task where blocks of trials represented distinct states to probe wh
283 rformance of a task comprised of alternating blocks of trials requiring a saccade either toward a lar
284            Each session was divided into two blocks of trials.
285 ther, our data demonstrate that open-channel block of TTX-resistant currents, enhanced by gain-of-fun
286 ormations by a WDR60-WDR34 heterodimer and a block of two RB and six LC8 light chains.
287  sequences were computer-generated in random blocks of two and four, and stratified by site.
288 Participants were randomly assigned (1:1) in blocks of two using sequentially numbered sealed envelop
289 U) using computer-generated randomisation in blocks of two, stratified by type of home (residential o
290                       This report shows that blocking of type 2 immune responses can treat infection.
291 ace elevation change in intact mixed-species blocks of UK salt marsh using six open-top chambers rece
292 omputer-generated random numbers in balanced blocks of variable size.
293  wrinkled patterns are the critical building blocks of various flexible electronics, where the wrinkl
294  observed with the whole virus, and antibody blocking of viral G protein abrogated these responses.
295 mal external region (MPER) results in robust blocking of viral infection by a class of broadly neutra
296 as require the measurement of the potency of block of voltage-gated potassium channel subtype 11.1 (K
297       Here we analyzed the chemical building blocks of VPC-00628 that played a key role in achieving
298    Such habitats surround the Guinean forest block of West Africa(8) and accord with the locations of
299  measured White participants' habituation to blocks of White and Black faces that parametrically vari
300 ast to the single phase found for amantadine block of wild-type M2.

 
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