ライフサイエンスコーパス: blood lead

1 r which bone lead is a better biomarker than blood lead.

2 or folate deficiency, inflammation, or high blood lead.

3 SA-chelatable lead were similar to those for blood lead.

4 x 10(-6)) and independently associated with blood lead.

5 an the other two Asian subgroups, except for blood lead.

6 NPs affecting ALAD expression did not affect blood lead.

7 5% confidence interval (CI): 1.63, 1.70) for blood lead, 0.44 microg/L (95% CI: 0.42, 0.47) for blood

8 An interquartile increment in blood lead (2.8 microg/dl) was associated with 14% highe

9 (OR) 1.01 per effect size of log transformed blood lead, 95% confidence interval (CI) 0.97, 1.05), bl

10 mosome 9, showed consistent association with blood lead across countries and evidence for multiple in

11 The association between blood lead and blood pressure was stronger among persons

12 tively assessed the association between both blood lead and bone lead, analyzed with the use of K-she

13 D, in a prospective cohort study, using both blood lead and bone lead-a biomarker of cumulative lead

14 Blood lead and bone turnover may be associated with the

15 We examined associations of blood lead and cadmium (n = 6,796) and urine cadmium (n

16 Adjusting for blood lead and cadmium levels reduced this odds ratio to

17 ned by confounding due to smoking, increased blood lead and cadmium levels, and impaired renal functi

18 s in infants, the observed increases in cord blood lead and cadmium require further exploration.

19 dults, the highest (vs. lowest) quartiles of blood lead and cadmium were associated with 1.70 (95% CI

20 Blood lead and cadmium, at levels well below current saf

21 lead and with significant increases in cord blood lead and cadmium.

22 There was no association between blood lead and cancer mortality in this range of exposur

23 ntrol studies suggest an association between blood lead and essential tremor, and that this associati

24 Associations of survival time with blood lead and plasma biomarkers of bone resorption (C-t

25 controls to examine the association between blood lead and the risk of amyotrophic lateral sclerosis

26 Few studies have compared associations of blood lead and tibia lead with blood pressure and hypert

27 race/ethnicity) to evaluate associations of blood lead and tibia lead with systolic and diastolic bl

28 ealed associations of current lead exposure (blood lead) and past lead exposure (bone lead) with risk

29 variate analyses were performed with survey, blood lead, and environmental data.

30 tion rates through retrospective analyses of blood lead biomonitoring from the Bunker Hill Superfund

31 Biomarker data (blood cadmium, blood lead, blood mercury, urinary total arsenic, and ur

32 hites exhibit different associations between blood lead (BPb) and blood pressure (BP) and whether dep

33 We evaluated the association between blood lead (BPb) and urine arsenic (As), Cd, molybdenum

34 iron and EDTA, alone and in combination, on blood lead (BPb) concentration, iron status, and cogniti

35 s observe a continuous decline in children's blood lead (BPb), reservoirs of exposure persist in tops

36 significantly and positively associated with blood lead but only among postmenopausal women not using

37 There was no association between blood lead concentration and LTL.

38 We analyzed the relations between blood lead concentration and pubertal development among

39 Increased blood lead concentration as a function of fragmentation

40 is genetic variation between individuals in blood lead concentration but the polymorphisms contribut

41 rmed a previously reported U-shaped curve in blood lead concentration during pregnancy as well as fin

42 Elevated blood lead concentration during the neonatal period was

43 the median (+/-SD) increase from baseline in blood lead concentration for the supplemented group was

44 he trial, with an overall median increase in blood lead concentration from baseline to month 9 of 0.1

45 Mean blood lead concentration from birth to 78 months was ass

46 Blood lead concentration has been associated with mortal

47 Geometric mean blood lead concentration was 0.69 mug/dL (95% CI: 0.67,

48 Mean blood lead concentration was 6.43 microg/dL (SD = 2.64).

49 Elevated mean childhood blood lead concentration was also associated with a sign

50 microg per deciliter in the lifetime average blood lead concentration was associated with a 4.6-point

51 Blood lead concentration was associated with decreased w

52 ation between walking speed and quintiles of blood lead concentration was estimated separately in men

53 The relation between IQ and blood lead concentration was estimated with the use of l

54 The blood lead concentration was inversely and significantly

55 ent scores, an effect that is independent of blood lead concentration, suggesting that it is solely d

56 for child and family characteristics and IQ, blood lead concentrations >/=10 microg/dL vs <8 microg/d

57 lead concentrations <8 microg/dL, those with blood lead concentrations >/=8 microg/dL scored 2-3 poin

58 Compared to children with blood lead concentrations <8 microg/dL, those with blood

59 ong 13 participants with high umbilical cord blood lead concentrations (>/= 10 mug/dL) than in 42 par

60 /dL) than in 42 participants with lower cord blood lead concentrations (p = 0.08).

61 The association between blood lead concentrations 8-10 microg/dL and cognitive d

62 estimated the adjusted percent difference in blood lead concentrations and 95% confidence intervals (

63 Despite dramatic declines in children's blood lead concentrations and a lowering of the Centers

64 d the time course and prevalence of elevated blood lead concentrations and associated injury- and pat

65 Examine the relationships between blood lead concentrations and children's intelligence qu

66 e, we demonstrate that individuals with high blood lead concentrations and high concentrations of mul

67 y mediated the relationship between elevated blood lead concentrations and later school performance.

68 Mean blood lead concentrations and walking speeds were 2.17 m

69 The significant effect on blood lead concentrations during the first 4 mo was in t

70 y, older mothers showed steeper increases in blood lead concentrations during the latter half of preg

71 egated columns in the barrel field, produced blood lead concentrations from 1 to 31 microg/dl.

72 in IQ or school tests between children with blood lead concentrations groups 8-10 and >/=10 microg/d

73 We measured blood lead concentrations in 172 children at 6, 12, 18,

74 ead hazard control techniques did not reduce blood lead concentrations in asymptomatic children, but

75 xists that DMSA is effective in lowering the blood lead concentrations in children with levels betwee

76 Findings support that blood lead concentrations in early childhood, even <10 m

77 time it is labeled for use in children with blood lead concentrations in excess of 45 micrograms/dL.

78 0.19, -0.04; p-trend = 0.005) for women with blood lead concentrations in the highest versus lowest q

79 Q declined by 7.4 points as lifetime average blood lead concentrations increased from 1 to 10 microg

80 Blood lead concentrations of 3 microg per deciliter were

81 tment, current DMPA users (7% of cohort) had blood lead concentrations that were 18% higher than thos

82 Blood lead concentrations were measured in whole blood s

83 Blood lead concentrations were measured when children we

84 Mean baseline whole blood lead concentrations were slightly below the limit

85 For blood lead concentrations, 7.8% of children (n = 105) ha

86 Blood lead concentrations, even those below 10 microg pe

87 urrent DMPA use is associated with increased blood lead concentrations.

88 the association between current DMPA use and blood lead concentrations.

89 After analysis of blood lead data revealed spiking lead in blood of Flint

90 the coupled model estimates using real-world blood lead data, to quantify relative contributions by t

91 Blood lead determinations were made by atomic absorption

92 The pattern of blood lead during pregnancy was investigated in a cohort

93 Logistic models correctly predicted a blood lead elevation of >/=20 micro g/dl in 81% and 85%

94 nce of miscarriages and fetal death, even at blood lead elevations ( approximately 5 mug/dL) once con

95 llected from condors indicate lead exposure (blood lead >/= 200 ng/mL) that causes significant subcli

96 ns of participants in the highest tertile of blood lead (> or = 0.17 micromol/L [> or = 3.62 microg/d

97 his study raises questions about the role of blood lead in CAD.

98 mic status, each 5-microg/dL higher level of blood lead in childhood was associated with a 1.61-point

99 onfounders, each 5-microg/dL higher level of blood lead in childhood was associated with a 1.79-unit

100 However, the prevalence of elevated blood lead in children (>/= 10 mug/dL) remains high in s

101 rnal blood lead including the geometric mean blood lead in DC children (R(2) = 0.68) and the incidenc

102 lopmental assessment scores and decreases in blood lead in iron-replete children with lead poisoning

103 We demonstrate that low levels of blood lead, in the range seen in many impoverished inner

104 to 2007 correlated with proxies for maternal blood lead including the geometric mean blood lead in DC

105 Infant blood lead level (3.4+/-2.2 mug/dL) increased by 1.8 mug

106 re exposed to lead for > 12 months and had a blood lead level (BLL) > 70 mug/dL were enrolled (n = 86

107 childhood lead poisoning [>/= 1 child with a blood lead level (BLL) >/= 10 microg/dL] and lead contam

108 this study, lead poisoning was defined as a blood lead level (BLL) greater than or equal to 30 mug/d

109 We aimed to report environmental and blood lead level (BLL) in China, and investigate the rel

110 Blood lead level (BLL) is the routine measure used for d

111 evaluate the demographic characteristics and blood lead level (BLL) of these patients in the country

112 describe and evaluate the changes in venous blood lead level (VBLL) associated with DMSA treatment i

113 on intake quintile (<10.9 mg/day) had a mean blood lead level 1.1 microg/dl higher than men in the hi

114 n C intake quintile (<109 mg/day) had a mean blood lead level 1.7 microg/dl higher than men in the hi

115 confirming the association between elevated blood lead level and higher risk of ALS.

116 atistically significant associations between blood lead level and log-transformed white matter hyperi

117 The relationship between blood lead level and systolic and diastolic hypertension

118 Mean (SD) blood lead level at age 11 years was 10.99 (4.63) microg

119 Mean blood lead level at age 11 years was 10.99 (SD, 4.63) mu

120 levels over time to be associated with high blood lead level at the preceding visit.

121 ension increased with increasing quartile of blood lead level compared with quartile 1 (adjusted OR,

122 Blood lead level does not necessarily reflect the total

123 Differences in blood lead level explained some of the differences in ca

124 4.0%) for identifying children with a venous blood lead level greater than 10 mug/dL (5 studies [n =

125 ntrol and Prevention has defined an elevated blood lead level in children as > or = 10 microg/dl, on

126 ur previous study that estimated the natural blood lead level in humans (0.016 mug/dL), which is also

127 The geometric mean blood lead level in study participants was 0.12 micromol

128 the first six months of the trial, the mean blood lead level in the children given succimer was 4.5

129 Elevated blood lead level is associated with serious, often irrev

130 al exposure limit guidelines (40 microg/dL), blood lead level is positively associated with both syst

131 Blood lead level may be related with CVD in healthy olde

132 ldren (6 months to 12 years old) for routine blood lead level surveillance March-May 1993 were assaye

133 which produced a distorted notion about the blood lead level that can be considered "normal"; the pr

134 , in multivariable models, a 50% increase in blood lead level was associated with 26% increased odds

135 s, a 0.24-micromol/L (5-microg/dL) change in blood lead level was associated with an elevated risk of

136 a median 34-year follow-up, higher childhood blood lead level was associated with differences in some

137 In this update, an elevated blood lead level was defined according to the Centers fo

138 r covariates, each 5-mug/dL higher childhood blood lead level was significantly associated with 1.19-

139 Each 5-mug/dL higher childhood blood lead level was significantly associated with a 2.0

140 Blood lead level was significantly associated with both

141 The log of blood lead level was significantly associated with the n

142 Blood lead level was the principal exposure variable.

143 Associations of childhood blood lead level with deficits in verbal comprehension a

144 st showed a 3.7% (0.5-microg/dl) decrease in blood lead level with each higher category of tofu intak

145 ddition, the magnitude of the association of blood lead level with TNF-R2 level increased with age in

146 There were positive associations of blood lead level with total cholesterol and HDL levels,

147 for sociodemographic factors, birth weight, blood lead level, and tobacco smoke exposure, black carb

148 lower HRT, adjusting for child IQ, age, sex, blood lead level, maternal education, pre- and postnatal

149 Elevated blood lead level, morbidity, mortality, clinical predict

150 bone turnover were significant predictors of blood lead level.

151 phic region, frequency of dental visits, and blood lead level.

152 No association was found with blood lead level.

153 approximately 20% of free-flying birds have blood lead levels (>/=450 ng/mL) that indicate the need

154 th pitcher pumps may be at risk for elevated blood lead levels (>5 mug/dL).

155 ted with significantly lower adjusted median blood lead levels (1.8 microg/dl) than past use (2.6 mic

156 Four different blood lead levels (15 microg/dl, 20 microg/dl, 30 microg

157 number of children under age 6 y of age with blood lead levels (BLL) >/=10mug/dL is estimated at over

158 vitro bioaccessibility assay, and children's blood lead levels (BLL) were investigated in an urban ne

159 10 microg/dL); 97% (198/204) of children had blood lead levels (BLLs) >/= 45 microg/dL, the threshold

160 l study, we examined the association between blood lead levels (BLLs) and GFR measured by the plasma

161 However, the association between blood lead levels (BLLs) and insulin-like growth factor

162 ng water lead concentrations keep children's blood lead levels (BLLs) below specified values, conside

163 concentrations of soil and Pb aerosols, and blood lead levels (BLLs) in 367839 children (ages 0-10)

164 We describe the distribution of blood lead levels (BLLs) in U.S. women of childbearing a

165 Elevated blood lead levels (BLLs) in young children are also asso

166 Blood lead levels (BLLs) less than 1.21 micromol/L (<25

167 ilable lead from these sources to children's blood lead levels (BLLs) monitored during cleanup from 1

168 valence ratio: 0.79, 0.71-0.88) and elevated blood lead levels (children <=16 years old, 5.2% versus

169 ths (0.5%) and 57 adults (0.4%) had elevated blood lead levels (defined as > or =0.72 micromol/L [15

170 immunodeficiency virus, as well as elevated blood lead levels (EBLL).

171 est tofu intake group (> or =750 g/week) had blood lead levels 11.3% lower (95% confidence interval:

172 Blood lead levels above 0.48 micromol/L (10 microg/dL) i

173 D analysis was only evident among those with blood lead levels above the median.

174 authors recommend continued surveillance of blood lead levels after gunshot injury for patients with

175 independently associated with decreased log blood lead levels among adults (P<.001), but not among y

176 iations of bone density-related factors with blood lead levels among women aged 40-59 years from the

177 ther dietary tofu intake was associated with blood lead levels among young adults in Shenyang, China.

178 An association between greater blood lead levels and a decline in IQ and socioeconomic

179 ALAD-2 allele has been associated with high blood lead levels and has been thought to increase the r

180 The association between blood lead levels and increased all-cause and cardiovasc

181 ly significant association between childhood blood lead levels and self-reported cognitive problems (

182 identify asymptomatic children with elevated blood lead levels are inaccurate.

183 no known safe level of lead for children and blood lead levels at and below 5 mug/dL are associated w

184 They determined blood lead levels at mean time points of 0.3, 3.1, 18.7,

185 New evidence regarding the blood lead levels at which morbidities occur have led to

186 udy was to determine the association between blood lead levels below 0.48 micromol/L and mortality in

187 neuropsychological function in children with blood lead levels below 45 microg per deciliter.

188 Treatment with succimer lowered blood lead levels but did not improve scores on tests of

189 65% to 68% decreased prevalence of elevated blood lead levels compared with adults in the lowest ser

190 had an 89% decreased prevalence of elevated blood lead levels compared with youths in the lowest ser

191 Pre-chelation geometric mean blood lead levels for children </= 5 years old decreased

192 However, workers who had elevated blood lead levels for more than 5 years had a higher ris

193 ps, and health department data on children's blood lead levels from the first 4 years of implementati

194 A change in blood lead levels from the lowest (quartile 1: range, 0.

195 Persons with blood lead levels greater than or equal to the cutoff le

196 Children's blood lead levels have declined worldwide, especially af

197 benefits and harms of screening for elevated blood lead levels in asymptomatic children 5 years and y

198 n the effectiveness of treatment of elevated blood lead levels in asymptomatic children 5 years and y

199 ms of screening for or treatment of elevated blood lead levels in asymptomatic children and pregnant

200 benefits and harms of screening for elevated blood lead levels in asymptomatic children.

201 benefits and harms of screening for elevated blood lead levels in asymptomatic pregnant persons.

202 benefits and harms of screening for elevated blood lead levels in asymptomatic pregnant persons.

203 Elevated blood lead levels in children are associated with neurol

204 acid (DMSA) chelation therapy found reduced blood lead levels in children at 1 week to 1 year but no

205 Here, 20 years of data on children's blood lead levels in Georgia were used to create maps to

206 nsity was significantly inversely related to blood lead levels in log-linear multivariate models that

207 eveloped a regression model to estimate mean blood lead levels in our population of interest, represe

208 ad stored in bone may significantly increase blood lead levels in perimenopausal women because of pos

209 ial distribution of blood lead screening and blood lead levels in the Atlanta area.

210 Blood lead levels in the range currently considered acce

211 sponse relation between tofu consumption and blood lead levels in this Chinese population.

212 on during pregnancy as well as findings that blood lead levels increase with age, smoking, lower educ

213 In mixed-model analyses, blood lead levels increased with time postinjury (p < 0.

214 Childhood blood lead levels measured at age 11 years.

215 Childhood lead exposure ascertained as blood lead levels measured at age 11 years.

216 We enrolled 780 children with blood lead levels of 20 to 44 microg per deciliter (1.0

217 r detecting disease clustering using data on blood lead levels of children who were patients at the K

218 Despite the marked decrease in blood lead levels over the past 3 decades, environmental

219 It is not known whether treatment to reduce blood lead levels prevents or reduces such impairment.

220 ortality was observed at substantially lower blood lead levels than previously reported.

221 gically menopausal women had adjusted median blood lead levels that were 25% and 30% higher, respecti

222 Geometric mean prenatal and postnatal blood lead levels were 1.9 micro g/dl (geometric SD +3.6

223 Mean blood lead levels were 13.2 microg/dl in men and 10.1 mi

224 6,800, 28,000 IU) vs. placebo, neonatal cord blood lead levels were 8.5% (95% CI: - 3.5, 22), 16% (95

225 Blood lead levels were also measured.

226 Blood lead levels were higher among cases compared with

227 Blood lead levels were measured in a nationally represen

228 Blood lead levels were negatively associated with tofu i

229 High blood lead levels were observed among children from all

230 Questionnaire data and serial blood lead levels were obtained from 105 participants (6

231 ears) with repeated measurements of bone and blood lead levels were studied.

232 These bone and blood lead levels were typical of those of community-exp

233 ndia should note the association of elevated blood lead levels with anemia and make further efforts t

234 uthors also observed inverse associations of blood lead levels with total dietary intake of vitamin C

235 ests that were significantly associated with blood lead levels, an increase in blood lead of 5 microg

236 pertension medications, including diuretics, blood lead levels, and hyperlipidemia, the odds ratios o

237 ls (measured by K-shell x-ray fluorescence), blood lead levels, and hypertension.

238 r pack-years of cigarette smoking, diabetes, blood lead levels, and intake of vitamin C, vitamin E, a

239 Blood lead levels, more indicative of short-term exposur

240 mately 10 times as high as the corresponding blood lead levels, suggesting that lead is being concent

241 hat postmenopausal bone resorption increases blood lead levels, the authors examined cross-sectional

242 environmentally exposed population with low blood lead levels.

243 .0005) or near joints (p = 0.032) had higher blood lead levels.

244 positive) were significantly associated with blood lead levels.

245 apy is not indicated for children with these blood lead levels.

246 ts can document a low prevalence of elevated blood lead levels.

247 ated with a decreased prevalence of elevated blood lead levels.

248 s of screening for and treatment of elevated blood lead levels.

249 accurately identifies children with elevated blood lead levels.

250 fy asymptomatic pregnant women with elevated blood lead levels.

251 urate for identifying children with elevated blood lead levels.

252 ronmental ones, are important in determining blood lead levels.

253 kers, although there is some suggestion that blood lead may be associated with tremor among the young

254 ho completed baseline questionnaires and had blood lead measurements taken in 1996-1998 as part of a

255 n = 670) and patella (n = 672) bone lead and blood lead (n = 807) among older men (age range, 50-98 y

256 iated with blood lead levels, an increase in blood lead of 5 microg/dl was equivalent to an increase

257 ssociated with a 1.7- micro g/dl increase in blood lead (p = 0.0001) in this group.

258 years), tremor increased significantly with blood lead (p = 0.03), but this pattern was not apparent

259 n, along with other neurotoxicants including blood lead (Pb) and serum cotinine, and child cognition.

260 e text] (DDE), hexachlorobenzene (HCB), cord blood lead (Pb), and maternal hair mercury (Hg).

261 this work is to examine associations between blood lead (PbB) and air lead (PbA) in particulate matte

262 It is difficult to discern the proportion of blood lead (PbB) attributable to ambient air lead (PbA),

263 Blood lead, plasma biomarkers of bone formation (procoll

264 Blood lead, plasma CTX, and plasma PINP were mutually ad

265 ification of genetic polymorphisms affecting blood lead reinforces the view that genetic factors, as

266 iation in the strength of the blood pressure-blood lead relation that has been observed in previous s

267 speed decreased with increasing quintiles of blood lead, resulting in an estimated mean value that wa

268 e maps to assess the spatial distribution of blood lead screening and blood lead levels in the Atlant

269 Efficient blood lead screening is crucial in the greater Atlanta a

270 Blood lead screening is recommended either universally a

271 one lead with estrogen status in determining blood lead supports the hypothesis that increased bone r

272 Capillary blood lead testing demonstrated sensitivity of 87% to 91

273 Thus, taking advantage of the program of blood lead testing in Arizona, condor blood samples from

274 rs, chronic kidney disease risk factors, and blood lead, the odds ratios for albuminuria (>or=30 mg/g

275 ional study to evaluate associations between blood lead, tibia lead, and dimercaptosuccinic acid (DMS

276 Means (standard deviations) for blood lead, tibia lead, and patella lead were 6.2 (4.1)

277 The relations of bone lead and blood lead to breast milk lead were modified by breastfe

278 ted that isolation of human neutrophils from blood leads to a spontaneous increase in their plasminog

279 Perfusion with blood leads to increased monocyte adhesion.

280 control elevated phenylalanine levels in the blood leads to increased risk of mental disabilities com

281 Activation of human MAIT cells in whole blood leads to MR1- and cytokine-dependent NK cell trans

282 lations we demonstrated that the addition of blood led to a differential expression of 154 genes.

283 Exposure to microfilaermic blood led to a significant decrease in average and maxim

284 n-lineage ZIKV infection of pregnant women's blood led to an exacerbated M2-skewed immunosuppression

285 Transfusion with old but not new blood led to intravascular hemolysis, acute hypertension

286 in skin areas, which are well supplied with blood, lead to more severe reactions and tested our hypo

287 tumors more rapidly and quickly cleared from blood, leading to a lower overall normal tissue exposure

288 in vivo K-shell X-ray fluorescence and cord blood lead using atomic absorption spectrometry.

289 The prevalence of elevated blood lead was 11.8% at 3 months and 2.6% at 12 months.

290 In these currently exposed workers, blood lead was a better predictor of neurobehavioral per

291 ead were negative for 16 of the 19 tests and blood lead was a significant predictor of worse performa

292 Blood lead was a strong and consistent predictor of both

293 ion with tibia lead was weaker and that with blood lead was absent.

294 Blood lead was analyzed by graphite furnace atomic absor

295 A doubling of blood lead was associated with a 1.9-fold increased risk

296 one lead was not associated with cancer, and blood lead was not associated with any mortality categor

297 Genetically instrumented blood lead was not associated with CAD (odds ratio (OR)

298 -frequency hearing loss (p-trend=0.003), but blood lead was not associated with hearing loss.

299 ates, the signs of the beta coefficients for blood lead were negative for 16 of the 19 tests and bloo

300 confidence intervals for the association of blood lead with ALS were estimated with unconditional lo