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1 lobin (Hb) has been evaluated as a potential blood substitute.
2 seases and/or when cell-free Hb is used as a blood substitute.
3 e blood was replaced with a hemoglobin-based blood substitute.
4 before and after isovolumic replacement with blood substitute.
5 ic blood replacement with a hemoglobin-based blood substitute.
6 romise for the production of stable Hb-based blood substitute.
7 f the oxidative toxicity of hemoglobin-based blood substitutes.
8 alues in the development of hemoglobin-based blood substitutes.
9 rable to that of erythrocytes for developing blood substitutes.
14 uential robotic liquid transfers of a common blood substitute by their endothelium-lined channels (as
15 r the optimal combination of oxygen-carrying blood substitute, colloid, and electrolyte solution for
18 application to the development of potential blood substitutes for the rare Bombay blood type that is
19 pproaches for the development of a synthetic blood substitute has been the engineering of novel mutan
20 ctive effects of cell-free, hemoglobin-based blood substitutes have been appreciated, the systemic ef
23 ed emulsion, PFC-Oxygent, has been used as a blood substitute; however, its role in cerebral blood fl
24 usion for > 3 hours with a cold asanguineous blood substitute, hypothermosol (HTS) solution, has been
25 (O(2)) carriers not only serve as potential blood substitutes in hemorrhage but also alleviate tumor
26 rHBOCs) have several potential advantages as blood substitutes in transfusion medicine, especially in
27 iscuss the development and current status of blood substitutes, including hemoglobin-based oxygen car
28 including blood transfusion, erythropoietin, blood substitutes, iron therapy, and minimization of dia
32 directed toward imaging the murine heart, a blood substitute may be applied to various optical diagn
34 oxidation of both recombinant MbO2 and HbO2 blood substitute prototypes without altering O2 affinity
35 two crystal structures of one such potential blood substitute, recombinant (r) Hb(alpha 96Val-->Trp),
37 lopments for the rational design of advanced blood substitutes that aim to address unmet clinical nee
38 of materials have been studied as candidate blood substitutes: the perfluorocarbons, modified hemogl
39 d blood cell transfusion or hemoglobin-based blood substitute therapy, the hemoglobinopathies, malari
40 ermittently fluidically coupled via a common blood substitute through their reservoirs of medium and
42 of whole blood and dilutions of blood with a blood substitute were determined with a spectrophotomete
43 including optimization of the development of blood substitutes where Hb is contained within phospholi