ライフサイエンスコーパス: body wall

1 uding the heart, neural tube, eyes, face and body wall.

2 derivative peptides) cause softening of the body wall.

3 ing are likely to be located in the animal's body wall.

4 hin the developing nervous system and in the body wall.

5 that connects the primitive gut tube to the body wall.

6 leading to bulging of the limb buds from the body wall.

7 vertebral fusion and closure of the ventral body wall.

8 thways by distorting the conformation of the body wall.

9 ic morphology with extensive coverage of the body wall.

10 on, for example, those that form the ventral body wall.

11 of appropriate attachment of the PHMP to the body wall.

12 e soft tissue sarcomas of the extremities or body wall.

13 roper development and closure of the ventral body wall.

14 g takes place continuously from the parental body wall.

15 spiratory trees, hemal system, tentacles and body wall.

16 ical ring, and the mesoderm of the secondary body wall.

17 ovide complete and independent tiling of the body wall.

18 he presumptive limb territory in the lateral body wall.

19 re appendicular derivations from the lateral body wall.

20 ion of the dorsal part of the thorax and the body wall.

21 iginating from the epithelium of the primary body wall.

22 t before it is stabbed through the partner's body wall.

23 etains a vestigial attachment to the ventral body wall.

24 ed syncytium that connects the uterus to the body wall.

25 several region-specific aspects of the adult body wall.

26 bit notum identity to properly subdivide the body wall.

27 elayed separation of foregut from the dorsal body wall.

28 forms ventrolateral dermis of the interlimb body wall.

29 IV dendritic arborization neurons, tile the body wall.

30 the herniation of organs through the ventral body wall, a decrease in the expression of Noggin, MyoD,

31 cripts enriched (two fold or greater) in the body wall and 56 transcripts enriched in the wing/hinge

32 ritic (md) sensory neurons tiling the larval body wall and a small number of bipolar neurons in the u

33 ects in the abdominal muscles of the ventral body wall and an enlarged umbilical ring, through which

34 h dendritic arborization (da) neurons in the body wall and can detect vibration with chordotonal orga

35 eurons has a soma associated with the dorsal body wall and hence is a putative stretch receptor in do

36 We examined MRP in embryonic body wall and intestinal muscles as well as in DFMs with

37 Os), which serve as stretch receptors in the body wall and joints and as auditory organs in the anten

38 lecules needed for touch sensation along the body wall and other regions of force sensitivity.

39 trale, an immense fascial pocket between the body wall and overlying blubber layer that reaches as fa

40 Abnormalities in body wall and sex muscles led to uncoordinated movement

41 merge from the neural tube, migrate into the body wall and siphon primordia, and subsequently differe

42 ns resulted in disappearance of MCs from the body wall and the accumulation of myofibroblasts in the

43 s rise to two distinct adult structures: the body wall and the wing.

44 ally be interpreted as a single touch to the body wall and used multiple suction electrodes to record

45 mpz-1 is expressed in about 60 neurons and body wall and vulval muscles.

46 les are more invasive, puncturing the female body-wall and inseminating directly into her body-cavity

47 : one directing UNC-89-A and -B primarily in body-wall and pharyngeal muscle, one internal promoter d

48 e a soluble LacZ reporter protein limited to body-wall and vulval muscles.

49 patterns, such as pannier, twist and Bar-H1 (body wall) and knot, nubbin and Distal-less (wing/hinge)

50 estricted motor columns that innervate limb, body wall, and neuronal targets, MMC neurons are generat

51 rvated completely overlapping regions of the body wall, and this finding suggests a lack of like-repe

52 (MASs), which connect somatic muscles to the body wall; and scolopale cells, which form an integral c

53 Human birth defects involving the ventral body wall are common, yet little is known about the mech

54 lpha functions in the closure of the ventral body wall, as well as offer insight into related human b

55 ect on the contractility of tube feet or the body wall-associated apical muscle, contrasting with the

56 digestive system (e.g., cardiac stomach) and body wall-associated muscles (e.g., apical muscle) and a

57 Nidogen is localized to body wall basement membranes and is required to direct l

58 cell body of ddaE repositions itself on the body wall between 25 and 40 hr after puparium formation

59 downregulated had defects in the dorsalmost body wall, but did not appear to have been globally repa

60 class II neurons do not completely tile the body wall, but they nevertheless occupy nonoverlapping t

61 overlapping dendritic coverage of the larval body wall by Drosophila class IV dendrite arborization (

62 velops in two stages: initially touching the body wall causes circumferential indentation (CI), an em

63 during embryogenesis with defects in ventral body wall closure and/or the heart.

64 Several tissues involved in normal ventral body wall closure are defective in the absence of AP-2al

65 otor-impaired NMII-B disrupts normal ventral body wall closure because of a dominant-negative effect.

66 since it has one of the most severe ventral body wall closure defects, thoracoabdominoschisis.

67 , yet little is known about the mechanism of body wall closure in mammals.

68 crest cell (NCC)-derived tissues, incomplete body wall closure, and abnormal skeletal patterning.

69 zation, linear heart tube formation, ventral body wall closure, and encasement of the fetus in extrae

70 caused perinatal lethality, edema, defective body wall closure, and skeletal abnormalities.

71 n external genital defects and disruption of body wall closure, as seen in the epispadias-extrophy co

72 During body wall closure, the left and right external genital p

73 complex morphological events responsible for body wall closure, we have studied this developmental pr

74 which these peptides affect the stiffness of body wall connective tissue are unknown.

75 n, causing a synergistic reduction of larval body wall contraction rate that is normally regulated th

76 After rapidly growing to establish body wall coverage, dendrites of Drosophila class IV den

77 sly described Hoxb2(PolII) alleles that have body wall defects have been shown to disrupt the express

78 ific role in monitoring different aspects of body-wall deformation.

79 on of Vn/Egfr target genes and explains both body wall development and wing outgrowth.

80 ermic genitalia to penetrate their partner's body wall during copulation, frequently bypassing the fe

81 ond to contractions in the Drosophila larval body wall during crawling.

82 neurons establish dendritic coverage of the body wall early in Drosophila larval development and the

83 intercalation processes occur during ventral body wall elongation and closure.

84 -encoded areas between native slow embryonic body wall (EMB) and fast indirect flight muscle myosin i

85 encoded domains between the native embryonic body wall (EMB) and indirect flight muscle isoforms (IFI

86 roportion to their substrate, the underlying body wall epithelium, as the larva more than triples in

87 grow synchronously with their substrate, the body wall epithelium, providing a system to study how pr

88 Electrical stimulation of the body wall evoked fast, short-duration spikelets in the M

89 he allantois, placental vasculature, ventral body wall, eye and heart.

90 f embryonic tissues such as the neural tube, body wall, face and eye lead to severe birth defects.

91 utant embryos fail to close the neural tube, body wall, face, and optic fissure, and they also displa

92 Otx2 are expressed primarily in the anterior body wall, foregut and developing nervous system.

93 stage 10-11 embryos, Hro-hh is expressed in body wall, foregut, anterior and posterior midgut, repro

94 Here, we show that the process of ventral body wall formation in Xenopus laevis is similar to hypa

95 ent with a model in which defects in ventral body wall formation require the simultaneous loss of at

96 after birth, with a severe defect in ventral body wall formation.

97 o control animals at E11.5, before secondary body wall formation.

98 2 and Hoxb4 in cell types that contribute to body wall formation.

99 The ventral body wall forms in the tadpole, while limb (appendicular

100 t cell types, as these cells are part of the body wall fragment.

101 rization (da) neurons, which tile the larval body wall, grow their dendrites mainly in a 2D space on

102 sis results in human birth defects involving body wall, gut, and heart malformations and in mouse mis

103 In arthropods, the body wall has served as a repeated source of morphologic

104 ms have circumferential reinforcement of the body wall; however, no experimental characterization of

105 contribute to closure of the neural tube and body wall; however, potential molecular regulators of th

106 rocess and are required for specification of body wall identities in the thorax; however, contrasting

107 The closure of the embryonic ventral body wall in amniotes is an important morphogenetic even

108 ated in the most ventral part of the primary body wall in Hoxb4(PolII) mutants.

109 bryos showed thinning of the primary ventral body wall in mutants relative to control animals at E11.

110 through toughening pre-existing parts of the body wall; in contrast, the subcoxal theory suggests ple

111 s directing the morphogenesis of the ventral body wall, including cell migration, differentiation, an

112 The projections to the foot and body wall indicate that serotonin may also participate i

113 thin two morphological classes partition the body wall into distinct, non-overlapping territorial dom

114 , PGCs migrate directionally from the dorsal body wall into the genital ridges.

115 suggest that widespread tiling of the larval body wall involves interactions between growing dendriti

116 hat a persistent somatopleure in the lateral body wall is a gnathostome synapomorphy, and the redistr

117 y little is understood about how the ventral body wall is formed.

118 gest that separation of the foregut from the body wall is genetically controlled and that defects in

119 As a result, the body wall is independently tiled by the beta and gamma d

120 hanism against loss of coelomic fluid if the body wall is punctured, and it may also function in the

121 Caenorhabditis elegans, gentle touch to the body wall is sensed by six mechanosensory neurons that e

122 sequently, the mesodermal compartment of the body wall is underdeveloped.

123 whereas exon 9b encodes one of the embryonic body wall isoform (EMB) relay domains.

124 the ventral ectoderm that protrudes from the body wall later covers only the paw.

125 gans of crawling caterpillars slide past the body walls like pistons in a new kind of legged locomoti

126 grating germ cells express CXCR4, whilst the body wall mesenchyme and genital ridges express the liga

127 We show that all body wall MNs are activated during both behaviors, but a

128 During reverse crawls, abdominal body wall movements are powered by phase-shifted contrac

129 During forward crawls, abdominal body wall movements are powered by simultaneous contract

130 rustaceans were incorporated into the insect body wall, moving the proximal exite of the leg dorsally

131 recognizing a key class of marker cells, the body wall muscle (BWM) cells, on a dataset of 175 C.eleg

132 redundantly with CeMyoD (HLH-1) in striated body wall muscle (BWM) fate specification in the C. eleg

133 intestine-specific SID-5 expression restored body wall muscle (bwm) target gene silencing in response

134 , normally containing exon 7d) and embryonic body wall muscle (EMB, normally containing exon 7a) isof

135 The results support the idea that body wall muscle activation contributes significantly to

136 ee novel UNC-97 interactors are expressed in body wall muscle and by antibodies localize to M-lines.

137 mple of this coupling is the interactions of body wall muscle and hypodermal cells in Caenorhabditis

138 a subset of neurons as well as in C. elegans body wall muscle and in male-specific diagonal muscles.

139 hat CLIK-1 is predominantly expressed in the body wall muscle and somatic gonad in which UNC-87 is al

140 mutation caused cytoskeletal defects in the body wall muscle and somatic gonad, whereas clik-1 deple

141 Descendants of MS contribute to body wall muscle and to the posterior half of the pharyn

142 We used body wall muscle as a test tissue because in conditions

143 f mammalian perlecan, that are important for body wall muscle assembly and attachment to basement mem

144 topaxin homolog in C. elegans, is located in body wall muscle attachments that are in vivo homologs o

145 The body wall muscle cells are a useful model for the study

146 ons suggest that gap junctions in C. elegans body wall muscle cells are responsible for synchronizing

147 The 81 embryonically born body wall muscle cells in C. elegans are comparable to t

148 jor components of the outward K+ currents in body wall muscle cells in culture.

149 in (GFP) secreted into the pseudocoelom from body wall muscle cells is endocytosed and degraded by co

150 roteins (Q29, Q33, Q35, Q40, and Q44) in the body wall muscle cells of Caenorhabditis elegans and sho

151 quires synchronous activities of neighboring body wall muscle cells.

152 (APs) and Ca2+ transients among neighboring body wall muscle cells.

153 d function, fertility and rhythmic posterior body wall muscle contraction (pBoc) required for defecat

154 One class of DMP mutants, called anterior body wall muscle contraction and expulsion defective (ae

155 ptic activation of SER-2 facilitates ventral body wall muscle contraction, contributing to the tight

156 provide mechanical stability for supporting body wall muscle contraction.

157 r circuit capable of detecting and modifying body wall muscle contraction.

158 However, genetic studies have shown that body wall muscle development occurs in the absence of HL

159 lines expressing GFP-Htt fusion proteins in body wall muscle displayed a polyQ repeat length-depende

160 roles, allocating mesodermal cells into the body wall muscle fate and patterning a subset of these m

161 High Twist levels direct cells to the body wall muscle fate, whereas low levels are permissive

162 Mutant embryos have an abnormal body wall muscle fiber pattern arising from defects in m

163 ssential for exercise adaptation, leading to body wall muscle improvements in structural gene express

164 holinergic receptor mediating contraction of body wall muscle in parasitic nematodes.

165 subunit composition for all three C. elegans body wall muscle ionotropic receptors provides a critica

166 ell as MgATPase V(max) compared to embryonic body wall muscle isoform (EMB) (expressed in a multitude

167 We find that dorsal acute body wall muscle myosin (EMB-9c11d) shows a significant

168 The body wall muscle of a Drosophila larva is generated by f

169 focal-adhesion-like structures found in the body wall muscle of the nematode Caenorhabditis elegans.

170 The Wnt CWN-1 is expressed in the posterior body wall muscle of the worm as well as in the SMs, maki

171 When ectopically expressed in body wall muscle precursor cells, hyperactivated EGL-15

172 Histochemical staining of larval body wall muscle revealed that the mutant A-type lamin,

173 se body complex and a conserved regulator of body wall muscle sarcomere organization and organelle po

174 Further, we find that sexual modification of body wall muscle together with the nervous system is req

175 mak-1 is expressed in nematode body wall muscle, and antibodies to MAK-1 localize betwe

176 ous tissues including the nervous system and body wall muscle, and knockdown of smn-1 by RNA interfer

177 his HA tag results in normal organization of body wall muscle, but approximately half the normal leve

178 multiple tissues - the epidermis, intestine, body wall muscle, ciliated sensory neurons and touch rec

179 as expressed in pharyngeal and tail neurons, body wall muscle, spermatheca, and vulva.

180 l for excitation-contraction coupling in the body wall muscle, through the coordination of calcium si

181 By polarized light microscopy of body wall muscle, unc-96 mutants display reduced myofibr

182 ssembly of sarcomeric actin filaments in the body wall muscle.

183 rganization of sarcomeric actin filaments in body wall muscle.

184 ls to distinct fates, such as heart, gut and body wall muscle.

185 eventually leading to an excess of hypaxial body wall muscle.

186 ak disorganization of the actin filaments in body wall muscle.

187 protein RNF-5 in the Caenorhabditis elegans body wall muscle.

188 ndrial localization to actin-rich I-bands in body wall muscle.

189 quired for proper actin filament assembly in body wall muscle.

190 fect and mild fiber degeneration in striated body wall muscle.

191 nization of all portions of the sarcomere in body wall muscle.

192 tal properties and molecular determinants of body-wall muscle APs.

193 tion (lf) mutants, SLO-1 was mislocalized in body-wall muscle but its transcription and protein level

194 wn that the focus of unc-52 action is not in body-wall muscle but most likely is in hypodermis.

195 arable to the junctional current (I(j)) into body-wall muscle cells caused significant depolarization

196 We found that body-wall muscle cells were electrically coupled in a hi

197 e UNC-9 expression in both motor neurons and body-wall muscle cells, analyses of miniature and evoked

198 In body-wall muscle cells, CTN-1 coclusters with SLO-1 at r

199 abditis elegans BK channel alpha-subunit, in body-wall muscle cells.

200 e made the first extracellular recordings of body-wall muscle electrophysiology inside an intact roun

201 rs are specified and there is a loss of most body-wall muscle fibers.

202 native indirect flight muscle and embryonic body-wall muscle isoforms only in the exon 7 region.

203 ment sites (M-lines and dense bodies) in the body-wall muscle of C. elegans.

204 Few body-wall muscle precursors are specified and there is a

205 hat ectopic germ cells preferentially induce body-wall muscle to extend cellular processes that enwra

206 increased frequency of Ca(2+) transients in body-wall muscle, and abnormal locomotion behavior.

207 irecting expression of UNC-89-C primarily in body-wall muscle, and one internal promoter directing ex

208 ine in autophagic activity in the intestine, body-wall muscle, pharynx, and neurons of wild-type anim

209 It also requires body-wall muscle, which is excited by EGL-30-stimulated

210 lectrical coupling in Caenorhabditis elegans body-wall muscle.

211 ent and not in most late embryonic or larval body-wall muscle.

212 ity assays and histochemical staining of the body-wall muscle.

213 exible polymers that connect the pharynx and body-wall-muscle basement membranes.

214 The MS blastomere produces one-third of the body wall muscles (BWMs) in the C. elegans embryo.

215 ng rhodopsins reported on voltage changes in body wall muscles (BWMs), in the pharynx, the feeding or

216 rsors, while later expression is observed in body wall muscles and a subset of pharyngeal neurons.

217 L(2)efl] is specifically expressed in larval body wall muscles and accumulates at the level of Z-band

218 kdown of lbx1 causes a specific reduction of body wall muscles and hypoglossal muscles originating fr

219 tes of MIF production are in the hypodermis, body wall muscles and in the nuclei of developing embryo

220 In contrast to many vertebrates, the ventral body wall muscles and limb muscles of Xenopus develop at

221 sion that leads to the formation of striated body wall muscles and non-muscle coelomocytes.

222 and for strong contractions of the posterior body wall muscles during defecation.

223 plementation is only slightly deleterious to body wall muscles during development or upon acute appli

224 been described in pharyngeal precursors and body wall muscles during embryogenesis, and amphid senso

225 neurons have defects in pathfinding and the body wall muscles have defective morphology.

226 number of identified motor neurons innervate body wall muscles in a highly stereotyped pattern.

227 s role of the affected pericardial cells and body wall muscles in developing and/or maintaining cardi

228 y, CYK-1 and FHOD-1, are present in striated body wall muscles near or on sarcomere Z lines, where ba

229 The larval body wall muscles of Drosophila melanogaster arise by fu

230 The body wall muscles require ongoing NAD(+) salvage biosynt

231 Formation of the Drosophila larval body wall muscles requires the specification, coordinate

232 ignalling from the pharyngeal MC neurons and body wall muscles slows larval development.

233 e isoform (EMB) (expressed in a multitude of body wall muscles).

234 inkages from the myofibrillar lattice of the body wall muscles, across an intervening extracellular m

235 road range of tissues from the intestine, to body wall muscles, and neurons.

236 zes with epithelial hemidesmosomes overlying body wall muscles, beginning at the time of embryonic cu

237 is shell is comprised of the cuticle and the body wall muscles, either of which could contribute to t

238 the mutant synthetase using cell-selective (body wall muscles, intestinal epithelial cells, neurons,

239 re impaired in the hermaphrodites, including body wall muscles, pharyngeal muscles and vulval muscles

240 RP-3 was expressed primarily in the anterior body wall muscles, suggesting that it may play a role in

241 chanosensation in C. elegans OLQ neurons and body wall muscles.

242 s apparent in the nerve ring, intestine, and body wall muscles.

243 usion and in myofibril assembly in embryonic body wall muscles.

244 e to particular pericardial cells and dorsal body wall muscles.

245 sor cells of the heart, visceral, and dorsal body wall muscles.

246 channelrhodopsin-2 to induce contractions in body wall muscles.

247 of aging Caenorhabditis elegans neurons and body wall muscles.

248 rgic motor neurons that synapse onto ventral body wall muscles.

249 e ZYX-1 protein is expressed in the striated body-wall muscles and localizes at dense bodies/Z-discs

250 Loss of clhm-1 in the body-wall muscles disrupts locomotory kinematics and bio

251 d by rhythmic and sequential contractions of body-wall muscles from the posterior to anterior segment

252 gle-copy transgenes that express rde-4(+) in body-wall muscles or hypodermis, however, enable silenci

253 Expressed in body-wall muscles, LECT-2 decorates neuronal processes a

254 y driving contraction waves of the abdominal body-wall muscles.

255 s in response to varying tonus of C. elegans body-wall muscles.

256 egmental ectoderm developed normally, as did body wall musculature and some other mesodermal derivati

257 he basal vertebrates, separate ventrolateral body wall musculature of the trunk into two discrete lay

258 all of the myoblasts that contribute to the body wall musculature, as well as in a group of cells th

259 ult satellite cells associated with limb and body wall musculature, as well as the diaphragm and extr

260 interfere with the proper development of the body wall musculature.

261 ential development of gut musculature versus body wall musculature.

262 Caenorhabditis elegans, morphogenesis of the body-wall musculature involves short-range migrations of

263 hey show unique features such as an inverted body-wall musculature or a novel pharyngeal organ.

264 , like mammalian skeletal muscle, C. elegans body-wall myocytes generate all-or-none APs, which evoke

265 dy segment, have dendrites tiling the larval body wall nearly completely without redundancy.

266 Body wall neurons showed a variety of distinct response

267 in wts mutants, dendrites initially tile the body wall normally, but progressively lose branches at l

268 the perineum-the caudal portion of the trunk body wall not associated with the hindlimb.

269 entral (DV) compartments and limb (wing) and body wall (notum) primordia.

270 iffening of mutable connective tissue in the body wall of A. japonicus, whilst holokinins (PLGYMFR an

271 The nerve terminals found in the body wall of Drosophila melanogaster larvae are readily

272 Pleurites are chitinous plates in the body wall of insects and myriapods.

273 ngs support an LPM contribution to the trunk body wall of these taxa, which is similar to published d

274 ressure waves (OPW), or shock wave, with the body wall or body armor produces two types of energy wav

275 h the neo gene has been removed did not have body wall or sternum defects.

276 evolutionary relationship between appendages/body-wall outgrowths in animals.

277 We elucidate how the four-layer body wall pattern, restricted to the non-mammal tetrapod

278 and cell apoptosis contributing to the open body wall phenotype.

279 the swimming rhythm expressed in nerve cord-body wall preparations and, at a different phase angle,

280 -distal axis into regions giving rise to the body wall (proximal), wing hinge (central) and wing blad

281 s whether wings are a novel structure on the body wall resulting from gene co-option, or evolved from

282 bstitutions in the turret (P90C, P89C/S97C), body wall (S65C/S190C, S65C/D315C) and the transmembrane

283 tome paired appendages form as outgrowths of body wall somatopleure, a tissue composed of somatic lat

284 y generate peptides (holokinins) that affect body wall stiffness in sea cucumbers, providing a novel

285 lial sheath, which are also expressed in the body-wall striated muscle.

286 and neurons receiving sensory input from the body wall synchronizes their growth to ensure proper den

287 aste organ, and three labeled neurons of the body wall that may be chemosensory.

288 pers, an ancestrally flat part of the dorsal body wall (the pronotum) was transformed into a three-di

289 including those associated with the primary body wall, the umbilical ring, and the mesoderm of the s

290 prevent the kidneys from detaching from the body wall, thus explaining their fusion and pelvic locat

291 ts of the pattern differentiating the future body wall tissue from the wing blade tissue.

292 failure of the lateral edges of the ventral body wall to fuse, leading to cardia bifida.

293 Ventral body wall (VBW) defects are among the most common congen

294 nimals revealed that unc-94a is expressed in body wall, vulval and uterine muscles, whereas unc-94b i

295 Second, the head and tail anchor while a body wall wave moves each abdominal segment in the direc

296 The anterior foot and body wall were densely innervated by 5HTli fibers but no

297 a neurons branch over defined regions of the body wall, which in some cases correspond to specific na

298 By mechanically stimulating the leech body wall while recording from mechanoreceptors, we show

299 into dorsoventral (DV) compartments and limb-body wall (wing-notum) primordia depends on Epidermal Gr

300 arbor and a smaller arbor in the peripheral body wall, with fewer terminal branches.