ライフサイエンスコーパス: bombesin receptor

1 vation in response to agonist stimulation of bombesin receptor.

2 vation in response to agonist stimulation of bombesin receptor.

3 osphorylation emanate from a single class of bombesin receptor.

4 g to their specific, high-affinity mammalian bombesin receptors.

5 nist with differing affinities for the known bombesin receptors.

6 vity studies using cell lines overexpressing bombesin receptors and the intracellular inositol monoph

7 -His-Sta-Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin receptor antagonist that targets gastrin-releas

8 -His-Sta-Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin receptor antagonist that targets gastrin-releas

9 l endopeptidase, which degrades bombesin, or bombesin receptor antagonists blocked bombesin-induced p

10 in and carbocyanine dyes to somatostatin and bombesin receptor-avid peptides and examined their recep

11 nase (MAPK) by a Gq/11-coupled receptor, the bombesin receptor (BR), and a Gi-coupled receptor, the D

12 ecipitated 60% of the solubilized [125I-Tyr4]bombesin/receptor complex prepared from either Swiss 3T3

13 to purified G protein alpha subunits by the bombesin receptor family, including gastrin-releasing pe

14 gh affinity agonists or antagonists at other bombesin receptors had an affinity >1000 nM.

15 as inhibited almost completely by a specific bombesin receptor inhibitor, [Tyr4, D-Phe12]-bombesin (1

16 a selective agonist for the BB(2) subtype of bombesin receptor, is reported to depolarise GABAergic i

17 Upon stimulation of the bombesin receptors, KUZ increases the docking and activa

18 subtype 3 (BRS-3), shares high homology with bombesin receptors (neuromedin B receptor (NMB-R) and ga

19 4, encoding a receptor related to vertebrate bombesin receptors, responds specifically to allatostati

20 the binding affinity of each peptide for the bombesin receptor site was determined.

21 both Galpha(q) and Galpha(13) in response to bombesin receptor stimulation.

22 lso attenuated PKD activation in response to bombesin receptor stimulation.

23 mediates PKD activation in response to acute bombesin receptor stimulation.

24 The mammalian bombesin receptor subfamily of G protein-coupled recepto

25 ed that U-87MG xenografts expressed mRNA for bombesin receptor subtype (BRS)-1 (GRP receptor) and BRS

26 rphan receptor discovered in 1993 was called bombesin receptor subtype 3 (BRS-3) because of 47-51% am

27 Human bombesin receptor subtype 3 (BRS-3) was cloned based on

28 (GRP-R), the neuromedin B receptor (NMB-R), bombesin receptor subtype 3 (BRS-3), and bombesin recept

29 (GRP-R), neuromedin B receptor (NMB-R), and bombesin receptor subtype 3 (BRS-3).

30 P-R), the neuromedin B receptor (NMB-R), and bombesin receptor subtype 3 (BRS-3).

31 uromedin B receptor (NMB-R, or bb1), and the bombesin receptor subtype 3 (BRS-3, or bb3).

32 We found that ARC(AgRP) neurons inhibit bombesin receptor subtype 3 (BRS3) neurons in the MPOA (

33 astrin-releasing peptide [GRP] receptor, and bombesin receptor subtype 3 [BRS-3]) in human non-small

34 ne expression, and identified mRNAs encoding bombesin receptor subtype 3 and neuromedin-B receptor (N

35 Neuromedin B (NMB) receptor-null and bombesin receptor subtype 3-null mice had the same respo

36 besin, gastrin-releasing peptide, NMB, and a bombesin receptor subtype 3-specific ligand induced mast

37 receptor (GRP-R), neuromedin B receptor, and bombesin receptor subtype 3.

38 R), bombesin receptor subtype 3 (BRS-3), and bombesin receptor subtype 4 (bb4).

39 ffinity, but they are diverged in BRS-3, the bombesin receptor subtype that binds bombesin with much

40 ed receptor (GPCR) agonists, stimulating the bombesin receptor subtype-3 (BB3) GPCR.

41 We cloned the gene and cDNA for rat bombesin receptor subtype-3 (BRS-3) and characterized it

42 Bombesin receptor subtype-3 (BRS-3) is an orphan G-prote

43 astrin-releasing peptide-preferring, and the bombesin-receptor subtype 3.

44 t the expression of the previously described bombesin-receptor subtype 4 is limited to amphibians.

45 Three mammalian bombesin receptor subtypes have been characterized: the

46 studies reveal that the structurally similar bombesin receptor subtypes, in particular BRS-3, possess

47 lish a contiguous signaling pathway from the bombesin receptor to ROCK in PC cells, and they implicat

48 and leukemia-associated RhoGEF (LARG), link bombesin receptors to RhoA in a non-redundant manner in

49 ombesin, whereas neither NMB nor a synthetic bombesin receptor type 3 ligand had any effect.