ライフサイエンスコーパス: bona fide

1 lasticity is revealed by a small fraction of bona-fide 14-mers (<4%) that may enable subunit exchange

2 mmunosorbent assay confirmed the presence of bona fide Abeta oligomers, whereas immunoprecipitation-W

3 inity purification identified N65 and N82 as bona fide acceptors for N-glycans.

4 or the installation of acetylation mimics or bona fide acetylation within H3 N-terminal tail alters t

5 that the FDA approved drug hydralazine is a bona fide activator of the NRF2/SKN-1 signaling pathway.

6 reported in Arabidopsis are indicative of a bona fide activity that can be associated with the regul

7 at these sites, and establish that PSGs are bona fide, acute, and persistent targets of WIN site blo

8 Finally, as predicted for a bona fide AD, mutation of this newly identified AD reduc

9 t insulin-stimulated phosphorylation of four bona fide Akt substrates (TSC2, PRAS40, FOXO1/3a, and AS

10 Thus, sphincter muscle cells are bona fide, albeit unconventional, photoreceptors.

11 Thus, CRAF is a bona fide alternative oncogene for BRAF/NRAS/GNAQ/GNA11

12 nclude electrochemical communication through bona fide AMPA receptor-dependent neuron-glioma synapses

13 Thus, Shisa7 is a bona-fide AMPAR modulatory protein affecting channel kin

14 tween TEs expressed from their own promoter (bona fide) and TEs that are transcribed from a neighbori

15 CD14(++)CD16- monocyte differentiation into bona fide anti-inflammatory Mvarphis in a self-autonomou

16 st immune responses(1,2) and can function as bona fide antigens that facilitate tumour rejection(3).

17 n a change in the acceptance of obesity as a bona fide area of academic interest.

18 me assembly defect is direct, i.e. New1 is a bona fide assembly factor, or indirect, for instance due

19 are well suited for such investigations, but bona fide astrocytes have not been described in this sys

20 fungus Chaetomium thermophilum captured in a bona fide autoinhibited state, which represents a novel

21 UIS3 acts as a bona fide autophagy inhibitor by competing with host LC3

22 Mature B2 cells differentiated into bona fide B1 cells upon acquisition of a B1 cell-typical

23 In addition, the bona fide bacterial PIMT enzymes may play a different or

24 The evidence of the other MBLAC2 role as a bona fide beta-lactamase allows for reassessment of beta

25 d NFIB associate with STAT5 at sites lacking bona fide binding motifs.

26 ndent 3'-5' polymerase activity of TLPs as a bona fide biological activity for the first time since i

27 find that shared variants largely represent bona fide biological occurrences of the same variant in

28 rB (YkuL), a protein of unknown function, as bona fide c-di-AMP-binding proteins.

29 cell invasion and for the Tarp effector as a bona fide C. trachomatis virulence factor.

30 nnectivity, demonstrating the plasticity and bona fide callosal potential of L4 neurons.

31 man malignancies, but whether they represent bona fide cancer drivers and therapeutically actionable

32 tagenesis studies revealed that Subdued is a bona fide CaPLSase.

33 Here, we identify a bona fide cardiac-specific Prkaa2 enhancer that is syner

34 We conclude that large COPII vesicles are bona fide carriers of PC1.

35 This allowed for dissecting bona fide caveolar functions from those supported by mer

36 ted that the majority of SI CD8 T cells were bona fide CD8 Trm cells that survived for >1 yr in the g

37 ful markers to distinguish CD8-MP cells from bona fide CD8(+) memory T cells, the developmental origi

38 wledge, this is the first demonstration of a bona fide cell adhesion molecule, NECL4, regulating chol

39 nd pannexin, which form gap junctions and/or bona fide cell surface channels.

40 ricentriolar-material antibodies to identify bona fide centrosomes and multiplexed these with cell bo

41 lective Sirt2 inhibitors with thalidomide, a bona fide cereblon ligand.

42 Our study correlates bona fide changes in PSP and CBD brains with cellular mo

43 disease models and human tumours: functional bona fide chemical synapses between presynaptic neurons

44 Among them, some members exhibited bona fide CHI activity, which catalyze stereospecific cy

45 However, so far the bona fide CHIs are found only in vascular plants, and th

46 Expressing those primitive bona fide CHIs in the Arabidopsis chi mutant restores th

47 cal Hedgehog (HH) pathway, for example, is a bona fide ciliary signalling system that regulates cell

48 We verified their bona fide circular topology using circular DNA deep-sequ

49 that the PDZ domain of nNOS can behave as a bona fide class III PDZ domain and bind to C-terminal se

50 sly distinguishing abortive coats (ACs) from bona fide clathrin-coated pits (CCPs) is required but un

51 Sulfolobus solfataricus TFS1 functions as a bona fide cleavage factor, while the paralogous TFS4 evo

52 e p53 transactivation domain have emerged as bona fide clinical candidates for reactivating the tumor

53 nstream start codon, likely representing the bona fide CLOCK N-terminus.

54 e heart were successfully captured including bona fide clusters of cells consistent with each major c

55 follow the constant curvature model and the bona fide CME population generates vesicles of a predomi

56 Recognizing AKI as a bona fide complication of diabetes should open up new av

57 hat activity-dependent processes are central bona fide components of neuronal TF-differentiation prog

58 consistent time-independent detection of its bona fide components.

59 re tightly than domains in proteins that are bona fide components.

60 ly identified, but nonetheless can represent bona fide compounds, also considerably complicates biolo

61 nalysis is a valuable method for identifying bona fide contributors to follicular lymphoma transforma

62 tus CcoA and Rhizobium leguminosarum RibN as bona fide copper and riboflavin importers, respectively.

63 vidence yet that visual deprivation produces bona fide cortical change.

64 ing some CD11c(hi) cells that may not have a bona fide counterpart in vivo.

65 Applying fliX-MS to cells identifies several bona fide crosslinks on DNA binding domains, paving the

66 containing ADA and Piccolo NuA4 complexes as bona fide crotonyltransferases that promote crotonylatio

67 erences in PKC-stimulated DAT trafficking in bona fide DAergic terminals.

68 her bolster the conclusion that CACNA1C is a bona fide, definite evidence long-QT syndrome susceptibi

69 5 promoted the protein stability of USP28, a bona fide deubiquitinase of LSD1.

70 d10 rescue studies revealed that Card10 is a bona fide direct miR-181b target.

71 y a universally conserved GTPase (HflX) as a bona fide dissociation factor of the S. aureus 100S ribo

72 Concentration-dependent polymerization via a bona fide DIX domain allows these to recruit ANGUSTIFOLI

73 , the structure provides a prime exemplar of bona fide domain-swapping.

74 Here we report that crenactin forms bona fide double helical filaments that show exceptional

75 trafficking proteins have been identified as bona fide drivers of tumorigenesis.

76 Our work thus identifies TRPA1 as a bona fide drug target for the amelioration of alpha-DC s

77 ial strategy towards eventual acquisition of bona fide drug-resistance mechanisms.

78 We demonstrate TaU4 to be a bona fide E2 enzyme through an E2 charging assay.

79 ligand binding domains of PPARgamma and is a bona fide E3 ligase for PPARgamma.

80 Here, we identified bona fide ECS signals, likely corresponding to carotenoi

81 ata identified lipopolysaccharide (LPS) as a bona fide effector caspase inhibitor that directly binds

82 ull-length protein from the first group is a bona fide effector protein injected into host cells duri

83 onents, ELL1 (also known as ELL) is the only bona fide elongation factor that directly stimulates tra

84 invasive high grade mammary carcinomas with bona fide EMT, histologically similar to human metaplast

85 However, validating such candidates as bona fide enhancers requires functional characterization

86 ck phase changes confirms that exercise is a bona fide environmental time cue for skeletal muscle.

87 Loktanella ALDH16 is found to be a bona fide enzyme, exhibiting NAD(+)-binding, ALDH activi

88 A total of 56 genes encoding bona fide enzymes catalyzing the consecutive ten steps o

89 Hence, Mfn2 stands as a bona fide ER-mitochondria tether whose ablation decrease

90 he master regulator of HSC identity(5), as a bona fide ERAD substrate that became aggregated in the e

91 erimental approaches required to distinguish bona fide EV cargo from merely co-purifying contaminants

92 activated T cells precludes it from being a bona fide exhaustion marker.

93 The bona fide F-box AnkB effector protein of L. pneumophila

94 for normal hematopoiesis and that Brca1 is a bona fide FA-like gene.

95 Because of the limited set of bona fide fibroblast markers, a proper characterization

96 thways, involving either the kleptoplasts or bona fide foraminiferal pathway(s) not yet identified.

97 However, it is crucial to demonstrate the bona fide formation of G4 structures within an endogenou

98 ed recombinant TIE protein was shown to have bona fide GA 2-oxidase activity.

99 e second intron of IncRNA, PVT1, as a unique bona fide gained enhancer that restored MYC transcriptio

100 ether are able to promote the development of bona fide gammadeltaT17 cells from peripheral CD122(-)IL

101 rovide definitive evidence that TRAPPII is a bona fide GEF for the yeast Rab11 homologues Ypt31/32.

102 rug-tolerant persister cells, which can seed bona fide genetic mechanisms of resistance to EGFR TKIs.

103 characterized, one enzyme was verified to be bona fide GGDPS and all others were demonstrated to func

104 lization of OSTERIX with OLFM4 and LGR5, two bona fide GI stem cell markers, at the crypt cells.

105 cin 3D microarray and confirmed one hit as a bona fide GLUT1 ligand, which we named rapaglutin A (RgA

106 e the crystal structure of ctPRC2 bound to a bona fide H3K27M sequence.

107 SDC-1 and SDC-2, but not SDC-3 or SDC-4, are bona fide HCV attachment receptors.

108 wever, this effect was not observed with the bona fide HCV IRES.

109 ssociated ultrastructural features represent bona fide HIV protein complexes.

110 dified AddAB even in the complete absence of bona fide hotspot sequences.

111 ular pluripotency via multiple mechanisms in bona fide hPSCs and reprogrammed cells.

112 ave clear implications for the generation of bona fide hPSCs for regenerative medicine.

113 f human pluripotent stem cells recapitulates bona fide human developmental haematopoiesis, and outlin

114 mammalian neural stem cell (NSC) fate and a bona fide human disease gene in congenital hydrocephalus

115 are not well characterized, specifically in bona fide human disease tissue.

116 we lack an equivalently vetted inventory of bona fide human enhancers.

117 This work demonstrates that BCAN-NTRK1 is a bona fide human glioma driver and describes a general st

118 itors using insights obtained from the first bona fide human immunoproteasome cocrystal structures.

119 The data indicate that tumors, including bona fide human NSCLC, can use lactate as a fuel in vivo

120 Bruton et al. developed a method to identify bona fide IgE(+) MBCs in humans, demonstrated their extr

121 We establish ZFP91 as a bona fide IMiD-dependent CRL4(CRBN) substrate and furthe

122 These results reveal that AARS1 is a bona fide in vitro substrate of METTL21C and suggest a r

123 is activated later during the transition to bona fide induced pluripotent stem cells (iPSCs).

124 of chitosans, which can now be recognized as bona fide information-carrying molecules.

125 ersion of the preinitiation complex (PIC) to bona fide initially transcribing complex (ITC), elongati

126 of glucose from the hemolymph, a hallmark of bona fide insulin action.

127 n assays to determine which of these exhibit bona fide interactions.

128 than 170 independent experiments, to filter bona fide interactors.

129 is, and epithelial junctional remodeling, as bona fide IRF6 partner proteins.

130 These data confirm that Neto2 is a bona fide KAR auxiliary subunit that is an important con

131 ein, and doublecortin-like kinase 1 and 2 as bona fide KLHL15 interactors and mapped KLHL15 interacti

132 that the cydD phenotype, unlike that of the bona fide l-cysteine exporter eamA, parallels that of th

133 , structural, and organizational features of bona fide LBs.

134 DS3-deficient mice confirmed that FADS3 is a bona fide LCB desaturase and required for the introducti

135 we demonstrated that those cells behaved as bona fide LCs when inserted in a three-dimensional rebui

136 These studies establish APOL1 as a bona fide LD-associated protein, and reveal that recruit

137 or the hypothesis that tetrapods inherited a bona fide limb regeneration programme concomitant with t

138 codes over observed cell types encodes their bona fide lineage relationships.

139 nd calcium imaging to determine how a set of bona fide lineage-related interneurons contribute to sen

140 age display to isolate peptides that possess bona fide LIR (LC3-interacting region) properties and ar

141 In summary, ALT joins PAN/nut1/T1.1 as a bona fide lncRNA of KSHV with potentially important role

142 matopoietic progenitors not derived from the bona fide long-term hematopoietic stem cells give rise t

143 Our findings uncover a key class of bona-fide LRRK2 substrates and a novel regulatory mechan

144 Our transcriptome-wide analysis identifies bona fide MARF1 target mRNAs and indicates that MARF1 pr

145 ing G protein-coupled receptor 5 (LGR5) is a bona fide marker of adult stem cells in several epitheli

146 suggests that MCD/C5s, as a class, represent bona fide MB tumors.

147 simple structural modifications of MD-222, a bona fide MDM2 PROTAC degrader, converts it into a "mole

148 e, our studies present deep insight into the bona fide mechanisms underlying castration resistance an

149 results establish the adhesion receptor as a bona fide mechanosensor that directly senses and respond

150 IL-12) improved accuracy in detecting bona-fide memory CD8 T-cell responses suggesting this as

151 FolR1 expression superimposes with Lmx1a, a bona-fide mesDA lineage marker, during the active phase

152 cations and hydrogen bonding structures in a bona fide metalloenzyme proton pathway.

153 EF) for the trimeric G protein Galphai and a bona fide metastasis-related gene that serves as a platf

154 In vitro MGE-like cells resembled bona fide MGE cells but expressed lower levels of Foxg1

155 visible via optical microscopy, making them bona fide microbes.

156 ntrast to other cell types of the human CNS, bona fide microglia have not yet been derived from cultu

157 , as other methods incorrectly classify most bona fide micropeptides as noncoding.

158 e question as to whether RNA viruses produce bona fide microRNAs (miRNAs) during infection has been t

159 l RNAs (sRNAs) but the biological role(s) of bona fide microRNAs (miRNAs) remains unclear.

160 lse positives, but surprisingly lacked >2000 bona fide microRNAs.

161 identified phosphodiesterase 7B (PDE7B) as a bona fide miR-200c target.

162 that MirCure can be used to revisit previous bona fide miRNAs annotations to improve miRNA databases.

163 understood features can clearly distinguish bona fide miRNAs from the myriad other small RNAs genera

164 ndrial dysfunction, which is associated with bona fide mitochondrial disorders.

165 nts leading up to the discovery of the first bona fide molecular catalyst system and follow with a co

166 ofiling, established that lot 150048 are not bona fide MT-4 cells.

167 ore, at temperatures too low for assembly of bona fide MTs, both tau isoforms promoted the formation

168 While some progenitors are bona fide multipotent and contribute progeny to all majo

169 biased screening of peptides recognized by a bona fide murine Treg cell clone isolated from the visce

170 lation is well established, the existence of bona fide N(omega)-methylarginine demethylases (RDMs) is

171 e cyclase AbyU, an enzyme shown here to be a bona fide natural Diels-Alderase.

172 te the physiological features of the desired bona fide neuronal subgroups remains an unanswered quest

173 Thus, ASICs have become bona fide neurotransmitter-gated ion channels, activated

174 uals also provides evidence for thousands of bona fide novel elements of RNA processing-alternative s

175 ulate FXR activity in vivo, thus providing a bona fide novel therapeutic agent to treat enterohepatic

176 We thus propose that PINs are a bona fide NPA target.

177 bundle in the helicase domain of Rep68 as a bona fide oligomerization domain (OD).

178 rtalized astrocytes, supporting AVIL being a bona fide oncogene.

179 Only a small number of genes are bona fide oncogenes and tumor suppressors such as Ras, M

180 key role in cell transformation, making it a bona fide oncometabolite.

181 lutarate (D-2-HG) have been characterized as bona fide oncometabolites.

182 tissues, we propose a high confidence set of bona fide palmitoylated proteins in brain and provide a

183 Surprisingly, T. brucei still contains a bona fide Pam18 orthologue that, while essential for nor

184 Our approach reliably discerns bona fide PAS from false PAS that arise due to internal

185 udy identifies c.620C>T;p.S207L as the first bona fide pathogenic RAD51D missense cancer susceptibili

186 dinate many facets of the immune response to bona fide pathogens as well as commensals.

187 ly express a subset of cellular genes, as do bona fide PEL cells.

188 However, validation of the effect of bona fide phosphorylation in vivo and assessing the ther

189 dent conformational changes are sensitive to bona-fide phosphorylation on S13 and S16 within the N17

190 elling support for the notion that WNK4 is a bona fide physiological intracellular Cl(-) sensor and t

191 Delamination of neural crest (NC) cells is a bona fide physiological model of epithelial-to-mesenchym

192 naceae, this is the first demonstration of a bona fide physiological role for a Tad pilus in this bac

193 dicate that both subunits of the complex are bona fide PKC substrates.

194 trials for managing Wnt-driven tumors, is a bona fide PORCN inhibitor whose IC50 for inhibition of W

195 tch forces at a similar level as observed in bona fide postnatal myocardium; (3) a positive force-fre

196 Finally, we argue that glucagon is a bona fide postprandial hormone that evolved to concurren

197 The bona fide PPARgamma activators we identified induced adi

198 ating from fatty acid synthesis pathway is a bona fide precursor of biotin in B. subtilis.

199 However, no bona fide primate pheromones have been identified.

200 In other disorders, the bona fide prion characteristics are still under investig

201 enerated in the absence of any cofactors are bona fide prions provides a strong support for the prote

202 ggregation-prone proteins are now considered bona fide prions.

203 oxide (O2()) and hydrogen peroxide (H2O2) as bona fide products in reactions involving 1- or 2-electr

204 Archaea are bona fide prokaryotes but employ a eukaryote-like transc

205 mHi-C also revealed biologically supported bona fide promoter-enhancer interactions and topological

206 Protection was long-lasting (>8 weeks) and a bona fide property of SA-4-1BBL, as treatment with an ag

207 imple structural modifications can convert a bona fide PROTAC degrader into a molecular glue compound

208 eria and chloroplasts, the identification of bona fide protease substrates has been very challenging.

209 detection that cannot be distinguished from bona fide protein isoforms.

210 CEACAM glycosylation, identifying CEACAMs as bona fide protein receptors for Hp.

211 ormations in the free form and when bound to bona fide Py-tract RNA ligands.

212 The bona fide quiescent CFs derived from human induced pluri

213 Mof deletion or FAO inhibition induces bona fide quiescent ground-state ESCs with an intact cor

214 both R7 and R8 photoreceptors target to the bona fide R7 target layer where they form connections wi

215 as a new regulator of body weight and as the bona fide receptor mediating the metabolic effects of GD

216 e-resolved redox events, and (ii) screen for bona fide redox-sensor targets.

217 ata presented here demonstrate that tRFs are bona-fide regulatory microRNA-like small RNAs involved i

218 onal exposure to THC-rich cannabis vapor has bona fide reinforcing properties and collectively suppor

219 Here we show that RUNX1 functions as a bona fide repressor of transcription activated by AML1-E

220 ysiology, illustrates the configuration of a bona fide resting state voltage sensor, observed without

221 c evidence that confirms its membership as a bona fide Rhodococcus.

222 ing in vitro analyses, we further focused on bona fide ribosome interactors (i.e. SEC61) and ER prote

223 with 7-mer and 16-mer synthetic bRNAs reveal bona fide RNA branchpoints in the Dbr1 active site.

224 The presence of bona fide RNA G4s in cells has long been a matter of deb

225 Here, we review the distinct features of bona fide RNA sensors, Toll-like receptors and retinoic-

226 demonstrate that Hfq CLASH robustly captures bona fide RNA-RNA interactions.

227 RNAi mutant flies, indicating that 340R is a bona fide RNAi suppressor, the absence of which uncovers

228 We demonstrate that YonO is a bona fide RNAP of the SPbeta bacteriophage that specific

229 Although iRPE displayed features close to bona fide RPE, no or a modest increase of the RPE65 prot

230 yses implicate the ompA RNA thermometer as a bona fide S. dysenteriae virulence factor in this bacter

231 a criterion to identify and characterize the bona fide SARS-CoV FP.

232 ow demonstrate that these CpdX compounds are bona fide selective GC receptor agonistic modulators (SE

233 Identifying TCRs directed against bona fide self-antigens is made difficult by the extraor

234 ggest that zebrafish explants do not undergo bona fide self-organization, but rather display features

235 lla-like protein phosphatase 2 (AtSLP2) is a bona fide Ser/Thr protein phosphatase that is targeted t

236 NIP2s (Nod26-like major intrinsic protein), bona fide silicon transporters, whereas EcLsi2 and EcLsi

237 We propose that NEMURI is a bona fide sleep homeostasis factor that is particularly

238 However, to date, only a very few bona fide small molecules have been reported against the

239 s of target proteins, with orally available, bona fide small molecules remains a significant but imme

240 We identify Dub3 as a bona fide Snail1 deubiquitinase, which interacts with an

241 This work establishes SORB-1 as a bona fide sorbin family protein-one of the late addition

242 ouse gustatory system, evidence that it is a bona fide sour taste receptor.

243 lived acinar cells that are not considered a bona fide source for stem cells.

244 ets McSCs to show that oncogenic McSCs are a bona fide source of melanoma that expand in the niche, a

245 pressive function of PTBP1 and its role as a bona fide splicing activator.

246 ostate physiology, identify c-MYC as a novel bona fide SPOP substrate, and help explain the frequent

247 We verified that this approach captures bona fide sRNA-mRNA interactions.

248 e ontogeny and adaptive purpose of IL-6 as a bona fide stress hormone coordinating systemic immunomet

249 Here, we demonstrate that lipin 1beta is a bona fide substrate for casein kinase II (CKII), a prote

250 ant by further defining PPP2R5 proteins as a bona fide substrate of HIV-1 Vif.

251 tion, suggesting that this mutated form is a bona fide substrate of this degradation pathway.

252 of approximately 1000 peptides identified 32 bona fide substrates of the plant NatB complex.

253 nd use it to provide evidence that SMT7 is a bona fide SUMO protease.

254 Neurons form bona fide synapses with oligodendrocyte precursor cells

255 e (pp-VSV-SARS-CoV-2 spike) that served as a bona fide system mimicking SARS-CoV-2 infection.

256 quivocally shown that psoriasis represents a bona fide T cell-mediated disease primarily driven by pa

257 ticity and loci-specific profiles similar to bona fide T(SCM) isolated from healthy donors, with inte

258 sease patients, and we provide evidence that bona-fide T3 phosphorylation alters Huntingtin exon 1 pr

259 itro and in vivo designate this protein as a bona fide target for the development of novel anti-TB in

260 uced induction of Bcl-xL and IkappaBalpha, 2 bona fide target genes of the canonical NF-kappaB pathwa

261 his research reveals that mitochondria are a bona fide target of Coxiella effectors and MceA is a com

262 MAP4 is a novel bona fide target of HPV16E7 protein which binds and recr

263 cular target evaluation in this uncommon yet bona fide target-rich disease.

264 cells by a process analogous to that used by bona fide TBDT ligands.

265 Here we report a simple strategy to examine bona fide TE expression, termed BonaFide-TEseq.

266 eukaryotic genomes have been shaped by both bona fide TE integration preferences in eukaryotic genom

267 ides a simple alternative approach to assess bona fide TE transcription at single-cell resolution and

268 ly elements, which have all the hallmarks of bona fide TEs yet which lack high homology with currentl

269 embles pseudopilins forming shorter Tff than bona fide Tfp-forming major pilins, underlining the evol

270 ms of cytokine production than either Th1 or bona fide Th17 cells, and produced increased amounts of

271 e results support the notion that SPHK1 is a bona fide therapeutic target for the treatment of AML.

272 applicability to the in vitro derivation of bona fide tissue progenitors of all germ layers.

273 the lung rather than residing in the lung as bona fide tissue-resident CD69(+) NK cells.

274 a repertoire employing TCRdeltaVs, NARTCRVs, bona fide trans-rearrangements from shark IgH clusters,

275 Mechanistically, we identified FOXO1 as a bona fide transcriptional repressor of HAS2.

276 chnologies for identifying cell lineages and bona fide transcriptional signals, it is necessary to co

277 with affected H3K27 acetylation contained a bona fide TRbeta1-binding site.

278 To determine whether these profiles reveal bona fide TREEs, we tested the sufficiency and requireme

279 tly, Th1/Tregs arise in atherosclerosis from bona fide Tregs, rather than from T-effector cells.

280 Bona fide trophoblast stem cell lines and extra-embryoni

281 Furthermore, bona fide TS and XEN cell lines can be derived from EPSC

282 Our biochemical analyses uncover CEP83 as a bona fide TTBK2 substrate with four phosphorylation site

283 ings provide genetic evidence that Bap1 is a bona fide tumor suppressor gene and offer key insights i

284 Merlin encoded by the Nf2 gene is a bona fide tumor suppressor that has been implicated in r

285 Long understood as a bona fide tumor suppressor that safeguards the integrity

286 Merlin/NF2 is a bona fide tumor suppressor whose mutations underlie inhe

287 tissue types, supporting its role as a broad bona fide tumor suppressor.

288 press endogenous GLS2, defying its role as a bona fide tumor suppressor.

289 mary, we provide evidence that both HATs are bona fide tumor suppressors that control MHCII expressio

290 We also establish H1 as a bona fide tumour suppressor and show that mutations in H

291 nzymatic CHIs, suggest that emergence of the bona fide type II CHIs is an ancient evolution event tha

292 archaeum subterraneum' operate together as a bona fide ubiquitin modification system, mediating a seq

293 e demonstrate that the protein Sov1 is an in bona fide VAR1 mRNA translational activator and addition

294 urthermore, GSC also transdifferentiate into bona fide vascular endothelial cells (GEC), which inheri

295 higher for men than for women, suggesting a bona fide "Vietnam War" effect.

296 tralizing antibody titers showed evidence of bona fide viral infection or experienced any symptoms du

297 t of our knowledge, the first characterized, bona fide virulence factor secreted by Acinetobacter spe

298 nd from primordial selfish genetic elements, bona fide viruses evolved on multiple, independent occas

299 report that BCL-2 ovarian killer (BOK) is a bona fide yet unconventional effector of MOMP that can t

300 ic TetR from S. agalactiae (PDB 3KKC) is the bona fide zinc efflux regulator SczA, and binds two zinc