ライフサイエンスコーパス: bone fracture

1 ions that are the consequence of spontaneous bone fracture.

2 (oim) resulted in a significant reduction of bone fracture.

3 ention, edema, congestive heart failure, and bone fracture.

4 uid retention, congestive heart failure, and bone fracture.

5 to alleviate the side effects of eczema and bone fracture.

6 n growth velocity and reduced frequencies of bone fracture.

7 3 participants experienced a frailty-related bone fracture.

8 on but was associated with a greater risk of bone fracture.

9 cancer, second primary cancer, and clinical bone fracture.

10 els, including osteoporosis, aging, and long bone fracture.

11 nd produce extracellular matrix, e.g., after bone fracture.

12 were death, heart failure, weight gain, and bone fracture.

13 adverse cardiovascular events and atraumatic bone fracture.

14 of adverse outcomes such as ketoacidosis and bone fracture.

15 stated when at least one observer suggested bone fracture.

16 ich play varying roles in the healing of the bone fracture.

17 tions and weight-bearing exercise to prevent bone fractures.

18 vasion occurs during endochondral healing of bone fractures.

19 lytic lesions in the ribs led to spontaneous bone fractures.

20 ith increasing incidence of osteoporosis and bone fractures.

21 e abnormalities that result in bone loss and bone fractures.

22 is not consistent with the high frequency of bone fractures.

23 cases at birth to mild cases with increased bone fractures.

24 d bone mass and become highly susceptible to bone fractures.

25 potential to revolutionize the treatment of bone fractures.

26 l impact force which could potentially cause bone fractures.

27 and/or increased prevalence of osteoporotic bone fractures.

28 steogenesis and vessel growth are coupled in bone fractures.

29 ma, and antibiotics <60 minutes in open long bone fractures.

30 oaches for maintaining mobility and to avoid bone fractures.

31 associated with an increased propensity for bone fractures.

32 lower in ALGS participants with a history of bone fractures.

33 ical illness have an increased prevalence of bone fractures.

34 ancy-related mortality, maternal sepsis, and bone fractures.

35 ers and frequently associate with pathologic bone fractures.

36 a new anabolic treatment for unconsolidated bone fractures.

37 with DS are increasingly more susceptible to bone fractures.

38 formation in patients with osteoporosis and bone fractures.

39 hich may have contributed to the increase in bone fractures.

40 n to spinal muscular atrophy with congenital bone fractures 2 (SMABF2).

41 ere found to localize a peptide payload to a bone fracture 91.9 times more than the control untargete

42 In the Medicare analysis, risk of bone fracture admissions at osteoporosis-related sites w

43 n, who are at high risk for osteoporosis and bone fractures after total body irradiation precondition

44 He also had multiple long bone fractures after trivial trauma over the past 8 year

45 pathologic phenotype is multiple spontaneous bone fractures-akin to those occurring in mouse models o

46 ity than either soft-tissue trauma or closed-bone fracture along with hemorrhage.

47 in K1) intake is a potential risk factor for bone fracture, although the mechanisms of this are unkno

48 ion between protein and risk of osteoporotic bone fractures among individuals has not been examined i

49 cts: genitourinary infections, ketoacidosis, bone fractures, amputations, acute kidney injury, perine

50 d of musculoskeletal conditions ranging from bone fracture and arthritis to skeletal cancer.

51 It is associated mainly with long bone fracture and bone marrow fat passage to the systemi

52 Moreover, the healing of bone fracture and critical-sized bone defects was also m

53 g pain severity, and was detectable for long-bone fracture and nephrolithiasis as well as among child

54 e clivus fracture without additional cranial bone fracture and neurologic deficit in the literature.

55 homocysteine (tHcy) may be a risk factor for bone fracture and osteoporosis.

56 , as it is associated with intractable pain, bone fracture and paralysis resulting from spinal cord c

57 NP site associated with an increased risk of bone fracture and predisposition to osteoporosis.

58 an effective therapy for conditions such as bone fracture and pulmonary arterial hypertension.

59 The combination of closed-bone fracture and soft-tissue trauma before hemorrhage l

60 er, our results suggest that a contralateral bone fracture and TBI alter the local neuroinflammatory

61 Polytraumatic injuries, specifically long bone fracture and traumatic brain injury (TBI), frequent

62 There were 3 (2.7%) bone fractures and 5 (4.5%) amputations.

63 th seven affected members exhibited frequent bone fractures and florid osseous dysplasia (p.Cys356Tyr

64 nhibits their osteolytic effects, preventing bone fractures and inducing an osteogenic response with

65 air quality is a modifiable risk factor for bone fractures and osteoporosis, especially in low-incom

66 The number of bone fractures and the renal safety profile were similar

67 The probability of bone fractures and time to first fracture were not diffe

68 f connective tissue characterized by brittle bones, fractures and extraskeletal manifestations.

69 Secondary outcomes included osteoporosis, bone fracture, and a composite event (any of these).

70 followed by facial or orbital fracture, long bone fracture, and chest injury.

71 d with premature mortality, injurious falls, bone fracture, and disability.

72 or-induced bone destruction, delayed time to bone fracture, and increased the use of the tumor-bearin

73 ity and use, delay the time to tumor-induced bone fracture, and maintain body weight.

74 orrhages (ICH), any type of fracture, facial bone fracture, and skull vault fracture.

75 , including a higher incidence of bone pain, bone fractures, and new-onset osteoporosis.

76 luding rheumatoid arthritis, osteoarthritis, bone fractures, and periodontitis.

77 Hospitalizations for pneumonia, bone fractures, and planned percutaneous coronary interv

78 esity, type 2 diabetes, metabolic disorders, bone fractures, and psychopathologies.

79 T3 deficiency, there were few pneumatoceles, bone fractures, and teething problems.

80 kidney and prostate stones, aortic stenosis, bone fractures, and tendon, ligament and/or muscle ruptu

81 deficiency is associated with bone loss and bone fractures, and the identification of vulnerable pop

82 mitant traumatic brain injury (TBI) and long bone fracture are commonly observed in multitrauma and p

83 Osteoporosis, osteopenia, and bone fracture are particularly common in these patients,

84 Long bone fractures are a concern in long-duration exploratio

85 Bone fractures are common impact injuries typically reso

86 Osteoporosis and bone fractures are increasingly recognized complications

87 Osteopenia and bone fractures are significant causes of morbidity in ch

88 between 2002-2013 and estimated the risk of bone fracture associated with ADPKD as compared to other

89 hat may play an important role in congenital bone fractures associated with type I spinal muscular at

90 She had multiple bone fractures at birth and was diagnosed with cutis lax

91 5 733; 27%) with surgical correction of long bone fractures being the most common procedure (144 997;

92 images were viewed for detection of possible bone fracture, bone edema and soft tissue injuries.

93 Cancer survivors may be at increased risk of bone fractures, but research is limited in several impor

94 ESRD have a substantially increased risk of bone fractures, but the burden of fractures has not been

95 ed metal debris showed metal particles and a bone fracture callus on the osseous defect.

96 Bone fracture callus samples were collected and analyzed

97 Specifically, mouse bone fracture callus specimens were extracted into a sin

98 t increased risk of falling experienced more bone fractures caused by falling (adjusted hazard ratio

99 Bone fractures commonly repair by forming a bridging str

100 ed with sulfonylureas and increased risk for bone fractures compared with metformin.

101 as associated with an increased frequency of bone fractures compared with placebo.

102 ia, osteoporosis, and increased incidence of bone fractures, considerable effort has been devoted to

103 of a deep neural network (DNN) approach for bone fracture diagnosis based on the non-invasive propag

104 While bone marrow injury, such as by bone fracture, disrupts marrow vasculature, the conseque

105 Bone fracture elevates oxygen tension in the injured bon

106 ability of treatment weighting, although the bone fracture end point approached statistical significa

107 isk with clopidogrel and PPI coprescription, bone fractures, enteric infections and pneumonia.

108 ough the reduction of both breast cancer and bone fracture event rates, the risks of both invasive en

109 Although bone fracture has become a serious global health issue,

110 ppression in premenopausal women) to prevent bone fractures has not been substantiated, although it s

111 Recently, osteoporosis and bone fracture have emerged as sexually-dimorphic comorbi

112 , adverse effects such as heart problems and bone fractures have already been reported.

113 As many as 10% of bone fractures heal poorly, and large bone defects resul

114 te injury has been associated with decreased bone fracture healing and increased rates of nonunion in

115 micelles' therapeutic efficacy in promoting bone fracture healing as demonstrated by micro-CT and hi

116 Bone fracture healing impairment related to systemic dis

117 ivation of EP4, but not EP2 rescued impaired bone fracture healing in COX-2(-/-) mice.

118 odels natural callus development to simulate bone fracture healing in rodents.

119 Bone fracture healing is a complex process with distinct

120 nin signaling in the remodeling phase during bone fracture healing is currently unknown.

121 Importance: Failure of bone fracture healing occurs in 5% to 10% of all patient

122 These effects lead to improved bone fracture healing quality compared with wildtype mic

123 Clinical determination of bone fracture healing remains qualitative, typically det

124 tal stem/progenitor cells that contribute to bone fracture healing.

125 robust inflammatory response that resembles bone fracture healing.

126 e progenitor cells and their contribution to bone fracture healing.

127 to both chondrocytes and osteoblasts during bone fracture healing.

128 n be expected for Zn alloys when considering bone fracture healing.

129 atic injuries, in part through inhibition of bone fracture healing.

130 GS correlate with markers of cholestasis and bone fracture history.

131 reduce the risk of symptomatic pathological bone fracture (HR 0.62, 95% CI 0.35-1.09), or the need f

132 1.06-1.17] vs 1.18 [95% CI, 1.16-1.19]) and bone fracture (HR, 1.35 [95% CI, 1.28-1.42] vs 1.65 [95%

133 io [HR], 1.16; 95% CI, 1.15-1.17; P < .001), bone fractures (HR, 1.59; 95% CI, 1.55-1.62; P < .001),

134 ADPKD is not associated with higher rates of bone fracture in ESKD.

135 the odds ratio (OR) and hazard ratio (HR) of bone fracture in phakic subjects with cataract compared

136 f the heart in the context of EMD after long bone fracture in pigs.

137 bone loss may contribute to the high rate of bone fracture in PWH, a cause of significant morbidity a

138 y 30% higher among subjects who had suffered bone fracture in the torso (p < 0.0005).

139 igate the association between opioid use and bone fractures in 2008-2017 among adults registered in t

140 to investigate therapeutic avenues to treat bone fractures in children with autism.

141 ), sensory function (hearing), mobility, and bone fractures in defining vulnerable health classes.

142 ar constructs, we anticipate that healing of bone fractures in humans that have relied on immobilizat

143 us problem worldwide; it is characterized by bone fractures in response to relatively mild trauma.

144 as to summarize the risk of osteoporosis and bone fractures in schizophrenia patients.

145 evidence supports Clostridium difficile and bone fractures in susceptible populations.

146 tiretroviral therapy causes osteoporosis and bone fractures, increasing morbidity and mortality in pe

147 Bone fracture is a growing public health burden and ther

148 Osteoporosis resulting in bone fractures is a complication in patients with primar

149 ss of bone mineral density (BMD) and risk of bone fractures is undetermined.

150 In commercial flocks of laying hens, keel bone fractures (KBFs) are prevalent and associated with

151 We identified 13 bone fracture loci, all associated with estimated BMD (e

152 t on acute kidney injury requiring dialysis, bone fractures, lower limb amputations, ketoacidosis, ge

153 However, osteonecrosis and bone fracture may affect the accuracy of DXA.

154 action between microdefects, metabolism, and bone fracture mechanics.

155 total bones; P < 0.01), a greater number of bone fractures (median 4 versus 0; P < 0.01), and more f

156 Using a mouse tibial bone fracture model in vivo, we show that application of

157 ssful targeted intracrine therapy in a mouse bone fracture model.

158 evaluated and separated based on wet and dry bone fracture morphology/characteristics.

159 We found that severe polytrauma-bone fracture, muscle crush injury, and bowel ischemia-i

160 trauma, including nociceptive sensitization, bone fracture, muscle fibrosis and muscle fibre loss.

161 hird of ONJ patients also suffered from long bone fractures (n = 4) and/or avascular necrosis of the

162 atients after surgical stabilization of long bone fractures of which six patients had impaired fractu

163 nned to qualify 50 children treated for long bones fractures of the arm, forearm, thigh and lower leg

164 Large or complex bone fractures often need clinical treatments for suffic

165 gist-level performance in detecting scaphoid bone fractures on conventional radiographs of the hand,

166 Different traumatic insults, i.e., bone fracture or soft-tissue trauma in conjunction with

167 and in patients with other risk factors for bone fractures or C. difficile infection.

168 illbirth, neonatal death, shoulder dystocia, bone fracture, or any arm or hand nerve palsy related to

169 juries, such as bruising, bite marks, burns, bone fractures, or trauma to the head or abdomen.

170 Indeed, several skeletal diseases, such as bone fracture, osteonecrosis, and inflammation are chara

171 d more adverse effects, including infection, bone fracture, osteonecrosis, mood and behaviour problem

172 s resulted in a two-thirds reduction in long bone fractures (P < .01), with fewer fractures per mouse

173 Nonblindness was associated with nasal bone fractures (P = .047).

174 Iliac crest-BM was aspirated from long-bone fracture patients with normal healing (U) or non-un

175 ially caused by low levels of hormones (e.g. bone fractures, poor sperm quality, and perhaps testicul

176 as been associated with an increased risk of bone fracture, raising concerns about their increasingly

177 Osteoporotic bone fracture rates are highest in countries that consum

178 (CAC) is associated with an enhanced risk of bone fracture, reduced bone density, and osteoporosis.

179 Treating osteoporosis and associated bone fractures remains challenging for drug development

180 ones regulate bone regeneration, we compared bone fracture repair between adult male and female mice.

181 Bone fracture repair initiates by periosteal expansion.

182 ting evidence that EM field therapy promotes bone fracture repair through mitochondrial OxPhos activa

183 Bone fracture repair was analyzed in femora of adult mic

184 is, fibrin was entirely dispensable for long-bone fracture repair, as healing fractures in fibrinogen

185 epair, the precise contribution of fibrin to bone fracture repair, whether supportive or detrimental,

186 nd mandibular condyle development and during bone fracture repair.

187 e stage of fracture healing to ensure better bone fracture repair.

188 fibrin clearance results in derangements in bone fracture repair.

189 Large and aberrant bone fractures require ossification and concomitant vasc

190 .001), edema (35.6% vs. 24.9%, P<0.001), and bone fracture requiring surgery or hospitalization (5.1%

191 e molecular pathways ultimately impact whole bone fracture resistance.

192 Closed-bone fracture (right lower leg; external fixation) and/o

193 sess the association between insulin use and bone fracture risk in T2DM patients.

194 rders and has been associated with increased bone fracture risk.

195 orbing periosteal osteoclasts, and increased bone fracture risk.

196 that the micelles would passively target to bone fracture sites associated with hematoma and inflamm

197 ity occurred with the combined insult (i.e., bone fracture/soft-tissue injury and hemorrhage) than af

198 pedic consultation should be sought for long-bone fractures, spinal cord compression, and vertebral c

199 y Hospital Prospective Evaluation of Risk of Bone Fractures study cohort of older women, performed in

200 Acute wrist injuries are predominantly bone fractures, such as those of the scaphoid, hamate ho

201 ifferences in the propensity to nontraumatic bone fracture suggest that genetic factors are important

202 We further found that highly specific bone fracture targeting of multiple peptidic cargoes can

203 riteria for assessing the timing of tooth or bone fracture, the assessment of events perimortem conti

204 In patients with long bone fractures, the presence of an RLS is associated wit

205 splatin plus gemcitabine group (pathological bone fracture, thrombocytopenia with subcutaneous haemor

206 E4 allele (APOE*E4) has been associated with bone fracture through a putative effect on vitamin K tra

207 of forced detraining due to incidental limb bone fracture underwent clinical assessment, ECG, and co

208 elation between stem cell number and time to bone fracture union in a human patient cohort.

209 f the presumed mechanism of fifth metatarsal bone fracture was attempted.

210 The risk of clinical bone fracture was higher in the 5-year group than in the

211 Bone fracture was observed in 5.6% of participants.

212 erence: children >=12 years), whereas facial bone fractures were more frequently encountered in boys

213 uma Score, initial visual acuity and frontal bone fractures were predictive of NLP (P = .006 and P =

214 During follow-up, no bone fractures were reported to have occurred; 12/368 cr

215 t bone remodeling and cause osteoporosis and bone fracture when given continuously or in high doses.

216 potential for harm (major tissue damage and bone fractures) when commonly found objects in a healthc

217 ns, when the control group was patients with bone fracture, when anxiety and depressive disorders wer

218 ical effects in bones, and specifically near bone fractures, where flexoelectricity is theoretically

219 le interventions to reduce the likelihood of bone fractures with age.

220 In this study, we fixed mouse long bone fractures with external fixators and bone plates.