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1 itions and vascular calcification, including bone morphogenetic protein (BMP) and transforming growth
3 t in the context of reduced ShcA levels, the bone morphogenetic protein (BMP) antagonist chordin-like
5 cted gene aberrant in neuroblastoma (DAN), a bone morphogenetic protein (BMP) antagonist we detected
6 e that CHRDL1 encodes Ventroptin, a secreted bone morphogenetic protein (BMP) antagonist, the molecul
10 evelopment, with a classic example being the bone morphogenetic protein (BMP) gradient's conserved ro
12 iron homeostasis by direct interaction with bone morphogenetic protein (BMP) ligands to induce hepci
13 that injury stimulates the production of two bone morphogenetic protein (BMP) ligands, Dpp and Gbb, w
14 equencing (ChIP-seq) data, we identified the bone morphogenetic protein (BMP) pathway as a potential
18 in particular the dual modulation of Wnt and bone morphogenetic protein (BMP) pathway signaling, this
19 on the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) pathway, which is one o
23 its surrogate surface marker P2RY1, and the bone morphogenetic protein (BMP) receptor 1A (BMPR1A)/ac
25 ated that OA-MSC expressed the same level of Bone Morphogenetic Protein (BMP) Receptor-1A as OAC but
27 ransforming growth factor beta (TGFbeta) and bone morphogenetic protein (BMP) signal transduction in
28 red neogenic hair follicles, which triggered bone morphogenetic protein (BMP) signaling and then acti
29 cal and genetic epistasis studies identified bone morphogenetic protein (BMP) signaling as a mediator
32 Loss of the growth-suppressive effects of bone morphogenetic protein (BMP) signaling has been demo
33 mice were carried out to assess the role of bone morphogenetic protein (BMP) signaling in psoriatic
34 lly cryptic "secondary cells." Inhibition of bone morphogenetic protein (BMP) signaling in secondary
35 result of differential regulation of Wnt and bone morphogenetic protein (BMP) signaling in these two
37 has been constructed and, here, we show that bone morphogenetic protein (BMP) signaling is essential
40 function of an activity-dependent autocrine Bone Morphogenetic Protein (BMP) signaling pathway at th
42 ibit Ras signaling and may also activate the bone morphogenetic protein (BMP) signaling pathway in co
43 coagulation factor fibrinogen activates the bone morphogenetic protein (BMP) signaling pathway in ol
46 rates that RNAi silencing of a member of the Bone Morphogenetic Protein (BMP) signaling pathway, Deca
47 f these mutants target the components of the Bone Morphogenetic Protein (BMP) signaling pathway, reve
49 axis is established and patterned by Wnt and bone morphogenetic protein (BMP) signaling pathways, res
50 e through modulation of Hedgehog, Notch, and bone morphogenetic protein (BMP) signaling pathways.
53 between transforming growth factor beta1 and bone morphogenetic protein (BMP) signaling plays an impo
57 y element-binding protein (SREBP) signaling, bone morphogenetic protein (BMP) signaling, and glycosyl
58 SMAD1/5 transcription factors, activated by bone morphogenetic protein (BMP) signaling, are major re
59 Multiple invasion pathways including EMT, bone morphogenetic protein (BMP) signaling, chemokine si
61 elf-renewing SCs, Foxc1 activates Nfatc1 and bone morphogenetic protein (BMP) signaling, two key mech
62 per, notable for roles in Wingless (Wnt) and bone morphogenetic protein (BMP) signaling, were differe
69 nd transforming growth factor-beta (TGFbeta)/bone morphogenetic protein (BMP) signalling and illustra
70 wingless-related integration site (WNT), and bone morphogenetic protein (BMP) signalling interactions
71 es from a murine myeloma model, we find that bone morphogenetic protein (BMP) signalling is upregulat
72 n coupled fibroblast growth factor (FGF) and bone morphogenetic protein (BMP) signalling together wit
73 s myocardial trabeculation through Erbb2 and bone morphogenetic protein (BMP) signalling, we discover
75 pression and signaling are up-regulated, and bone morphogenetic protein (BMP) signals are impaired.
77 and Wnt/beta-catenin) or share (TGFbeta and bone morphogenetic protein (BMP)) core signaling compone
78 wingless-integrated site (Wnt)/beta-catenin, bone morphogenetic protein (Bmp), and fibroblast growth
80 ys, epidermal growth factor receptor (EGFR), bone morphogenetic protein (BMP), Jun kinase (JNK), JAK/
81 dels commonly increase signaling of the Wnt, bone morphogenetic protein (BMP), or Ras/ERK pathways, c
82 FE) is specified by sequential inhibition of bone morphogenetic protein (BMP), transforming growth fa
83 ial cells (recell-dTBs); 3) dTBs seeded with bone morphogenetic protein (BMP)-2 (dTB-BMPs); and 4) fr
85 owth factor (TGF)-beta family, TGF-beta1 and bone morphogenetic protein (BMP)-2, in synovial fibrobla
86 s of inducible nitric oxide synthase (iNOS), bone morphogenetic protein (BMP)-2, matrix metalloprotei
87 nd that iSMCs from HGPS donors overexpressed bone morphogenetic protein (BMP)-4, which plays a key ro
90 receptor and function as coreceptors for the bone morphogenetic protein (BMP)/growth differentiation
92 ad2/3 pathway and activation of the parallel bone morphogenetic protein (BMP)/Smad1/5 axis (recently
93 was accompanied by changes in expression of bone morphogenetic protein (BMP)/sons of mothers against
95 es the gene encoding hepcidin (HAMP) via the bone morphogenetic protein (BMP)6 signaling to SMAD.
97 d that mutations in the type II receptor for bone morphogenetic protein (BMPRII) underlie the majorit
98 s of VBA, with and without recombinant human bone morphogenetic protein (rhBMP)-2, under space-making
99 und that the extracellular metalloproteinase bone morphogenetic protein 1 (BMP-1) is involved in endo
102 ntified the secreted zinc metalloproteinase, bone morphogenetic protein 1 (BMP1), as responsible for
104 C1r/C1s, urchin embryonic growth factor, and bone morphogenetic protein 1 domain indicate that Mt2I28
105 einase with thrombospondin motifs) and BMP1 (bone morphogenetic protein 1)/Tolloid-like families, res
107 Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are secreted durin
108 terms of osteoblastic differentiation using bone morphogenetic protein 2 (BMP-2) added to the medium
109 ential delivery of essential growth factors, bone morphogenetic protein 2 (BMP-2) and vascular endoth
112 determining role of these residues, BG bound bone morphogenetic protein 2 (BMP-2) weakly or not at al
115 study, we discovered the double deletion of bone morphogenetic protein 2 (Bmp2) and bone morphogenet
119 e previously identified a nuclear variant of bone morphogenetic protein 2 (BMP2), named nBMP2, that i
121 GO with the growth factor recombinant human bone morphogenetic protein 2 (rhBMP-2), producing a scaf
124 ptide nanostructures amplified signalling of bone morphogenetic protein 2 significantly more than the
126 les, histochemical, and immunohistochemical (bone morphogenetic protein 2/4 [BMP2/4], osteocalcin [OC
128 n of bone morphogenetic protein 2 (Bmp2) and bone morphogenetic protein 4 (Bmp4) in the dental epithe
129 response to transient (24-36 h) exposure to bone morphogenetic protein 4 (BMP4) plus inhibitors of A
130 coprotein 1 (GLG1) expression and downstream bone morphogenetic protein 4 (BMP4) signaling and also r
131 es different concentrations of activin A and bone morphogenetic protein 4 (BMP4) to polarize cells in
132 peri-gastrulation-like fate patterning upon bone morphogenetic protein 4 (BMP4) treatment of geometr
139 le protocol, using defined medium containing bone morphogenetic protein 4 by which human pluripotent
141 e, miR-18a decreased the expression of BMP4 (bone morphogenetic protein 4) and HIF-1alpha (hypoxia-in
144 Recent work has suggested that increased bone morphogenetic protein 6 (BMP6) expression could alt
147 ether these molecules intersect in vivo with bone morphogenetic protein 6 (BMP6)/mothers against deca
150 ansforming growth factor beta (TGFbeta), and bone morphogenetic protein 7 (BMP7), CD1c(+) dendritic c
153 VEGF-A, VEGF-C, VEGF-D, VEGF-A isoform 121, bone morphogenetic protein 7, macrophage colony-stimulat
155 (drMM) in the presence of human recombinant bone morphogenetic protein 7/human recombinant fibroblas
156 cluding fibroblast growth factor 21 (FGF21), bone morphogenetic protein 8b (BMP8b), growth differenti
157 d endothelial cell signalling in response to bone morphogenetic protein 9 (BMP9) and BMP10 is of sign
160 T is caused by loss-of-function mutations in bone morphogenetic protein 9 (BMP9)-ALK1-Smad1/5/8 signa
163 recipitation-sequencing experiments on BMP9 (bone morphogenetic protein 9)-stimulated endothelial cel
166 otein negatively regulates the activities of bone morphogenetic protein and phosphoinositide 3-kinase
167 To address whether elevated activities of bone morphogenetic protein and PI3K/AKT signaling pathwa
168 valves demonstrated activation of canonical bone morphogenetic protein and Wnt/beta-catenin signalin
169 cardiogenic fate of CNC(kit) is regulated by bone morphogenetic protein antagonism, a signaling pathw
171 ase inhibitors, activin traps, hepcidin, and bone morphogenetic protein antagonists in treating cance
172 channels regulate release of the Drosophila bone morphogenetic protein Dpp in the developing fly win
176 GDF7 (rs3072), which encodes a ligand in the bone morphogenetic protein pathway, and TBX5 (rs2701108)
177 We analyzed the effect of Irf8 on TGF-beta/bone morphogenetic protein pathway-specific genes in DCs
178 /or cocaine due to severe down-modulation of bone morphogenetic protein receptor (BMPR) axis: the ant
179 ce suggests that serotonin, mutations in the bone morphogenetic protein receptor (BMPR) II gene, and
180 e mutations leading to reduced expression of bone morphogenetic protein receptor (BMPR) II, these mut
181 Monoallelic mutations in the gene encoding bone morphogenetic protein receptor 2 ( Bmpr2) are the m
183 Because decreased expression and function of bone morphogenetic protein receptor 2 (BMPR2) is observe
184 terized by endothelial dysfunction, impaired bone morphogenetic protein receptor 2 (BMPR2) signaling,
185 hat in SMC and EC contact cocultures, BMPR2 (bone morphogenetic protein receptor 2) is required by bo
186 with hyperactivating mutations of the type I bone morphogenetic protein receptor ACVR1 (Activin type
187 However, transforming growth factor beta and bone morphogenetic protein receptor II signaling, and hy
188 role of transforming growth factor beta and bone morphogenetic protein receptor II signaling, human
189 ifferential transforming growth factor beta, bone morphogenetic protein receptor II signaling, or car
191 tion of SMAD1 by activin A receptor type 1L, bone morphogenetic protein receptor type 1A, and bone mo
192 morphogenetic protein receptor type 1A, and bone morphogenetic protein receptor type 1B and phosphor
194 erozygous mutations in the gene encoding the bone morphogenetic protein receptor type 2 (BMPR2) are t
195 ith heritable PAH caused by mutations in the bone morphogenetic protein receptor type 2 (BMPR2) gene
196 l hypertension with germline mutation in the bone morphogenetic protein receptor type 2 (BMPR2) gene,
197 despite clinical and molecular similarity to bone morphogenetic protein receptor type 2 mutation-asso
201 duced aggregation; 2) rs11202221, in BMPR1A (bone morphogenetic protein receptor type1A), replicated
202 sed to track the expression of a manipulated bone morphogenetic protein receptor within the Brainbow
203 in accumulation of synaptic growth-promoting bone morphogenetic protein receptors in the cell body an
206 G85R) We found cell-autonomous activation of bone morphogenetic protein signaling in proprioceptor se
207 ith our demonstration that the activation of bone morphogenetic protein signaling in proprioceptors a
209 (Wnt), transforming growth factor-beta, and bone morphogenetic protein signaling pathways affect car
210 rse transcriptional programs associated with bone morphogenetic protein signaling, alveolar specifica
211 R/MEK/Erk1/2 signaling and downregulation of bone morphogenetic protein signaling, with negative and
214 showed that loss of PEAT modestly increases bone morphogenetic protein target gene expression and al
215 fferentially expressed genes were related to bone morphogenetic protein type 2 receptor (BMPR2) signa
216 ty of HPAH patients inherit mutations in the bone morphogenetic protein type 2 receptor gene (BMPR2),
217 DNA damage and impaired signaling of BMPR2 (bone morphogenetic protein type 2 receptor) via two down
219 Heterozygous germ-line mutations in the bone morphogenetic protein type-II receptor (BMPR-II) ge
220 ENG (endoglin) is a coreceptor for BMP (bone morphogenetic protein) 9/10 and is strongly express
222 Decapentaplegic, a homolog of the vertebrate bone morphogenetic protein) from the wing imaginal disc.
224 tor cyclin-dependent kinase 1 decreases BMP (bone morphogenetic protein) signaling activity specifica
226 ntiation and new bone formation through WNT, bone morphogenetic protein, and Notch signaling pathways
227 ation of Hedgehog, fibroblast growth factor, bone morphogenetic protein, and Wnt signaling in the gen
228 , Indian hedgehog, fibroblast growth factor, bone morphogenetic protein, and Wnt signaling pathways i
229 ignaling pathways, including Sonic hedgehog, bone morphogenetic protein, fibroblast growth factor, tr
230 niche signalling pathways, specifically Wnt, bone morphogenetic protein, Notch and epidermal growth f
233 ts C1r and C1s, sea urchin protein Uegf, and bone morphogenetic protein-1) domains (distal domains).
235 lial growth factor A (VEGFA), interleukin-2, bone morphogenetic protein-10, VEGFC, and 2 (FGF2) were
236 Growth differentiation factor-9 (GDF9) and bone morphogenetic protein-15 (BMP15) are co-expressed e
237 rently, sustained in vivo delivery of active bone morphogenetic protein-2 (BMP-2) protein to responsi
238 ch as fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 (BMP-2) work synergisticall
240 gulates differentiation of OCs downstream of bone morphogenetic protein-2 (BMP-2)-stimulated osteobla
241 l with a collagen scaffold soaked in saline, bone morphogenetic protein-2 (BMP-2; 200 ng), 1 muM CGS2
242 al and temporal release of recombinant human bone morphogenetic protein-2 (BMP2) and vascular endothe
244 on of mesenchymal stem cells (MSCs), whereas bone morphogenetic protein-2 (BMP2) promotes osteogenic
246 In osteoblasts, CypA is necessary for BMP-2 (Bone Morphogenetic Protein-2)-induced Smad phosphorylati
247 tor (RUNX)-2, integrin binding sialoprotein, bone morphogenetic protein-2, osteocalcin, and cementum
251 es for hESC differentiated to TB by means of bone morphogenetic protein-4 and inhibitors of activin A
252 t Six1 and Six2 regulate both endothelin and bone morphogenetic protein-4 signaling pathways to patte
253 echanisms involved revealed the induction of bone morphogenetic protein-7 (BMP7) expression, a critic
256 Our objective is to determine circulating Bone morphogenetic protein-9(BMP-9) levels in subjects w
257 ilarly, wild-type (WT) animals, in which the bone morphogenetic protein-mothers against decapentapleg
260 es with sLR11 inhibits thermogenesis via the bone morphogenetic protein/TGFbeta signalling pathway an
261 ay), and that they activate cardioprotective bone-morphogenetic-protein signalling in cardiomyocytes.
263 f CR-CSCs to chemotherapy and the ability of bone morphogenetic proteins (BMP) to promote colonic ste
267 glands are specified by mesenchymal-derived bone morphogenetic proteins (BMPs) and fibroblast growth
279 the K19/14 sites in the promoter regions of bone morphogenetic proteins (BMPs) genes, which were ass
280 trauma with an osteo-inductive agent such as bone morphogenetic proteins (BMPs) has been considered a
281 gnaling involves binding to and sequestering bone morphogenetic proteins (BMPs) in the extracellular
283 rcomes the inhibitory effect of lung-derived bone morphogenetic proteins (BMPs) on self-renewal and t
287 anoid cultures, such as those involving Wnt, bone morphogenetic proteins (BMPs), Notch, and Hedgehog
288 ignaling by Sonic hedgehog (SHH) followed by Bone morphogenetic proteins (BMPs), regulate a dynamic e
292 hat supplementation of exogenous recombinant bone morphogenetic proteins 7 effectively ameliorates en
294 operate locally (e.g., Wingless/Ints [Wnts], Bone Morphogenetic Proteins [BMPs], and Hedgehogs [Hhs])
295 decapentaplegic (dpp), the homolog of human bone morphogenetic proteins BMP2 and BMP4, is a muscle-s
297 dysregulated transforming growth factor beta/bone morphogenetic proteins signaling and that this imba
298 ing, and that ligandless activity in the TGF/bone morphogenetic proteins signaling pathway contribute