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1 olic genes such as Sox9, Col2a1, and Acan by bone morphogenetic proteins.
2 und that the extracellular metalloproteinase bone morphogenetic protein 1 (BMP-1) is involved in endo
5 ntified the secreted zinc metalloproteinase, bone morphogenetic protein 1 (BMP1), as responsible for
7 C1r/C1s, urchin embryonic growth factor, and bone morphogenetic protein 1 domain indicate that Mt2I28
8 einase with thrombospondin motifs) and BMP1 (bone morphogenetic protein 1)/Tolloid-like families, res
11 ts C1r and C1s, sea urchin protein Uegf, and bone morphogenetic protein-1) domains (distal domains).
14 lial growth factor A (VEGFA), interleukin-2, bone morphogenetic protein-10, VEGFC, and 2 (FGF2) were
15 Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are secreted durin
16 Growth differentiation factor-9 (GDF9) and bone morphogenetic protein-15 (BMP15) are co-expressed e
17 terms of osteoblastic differentiation using bone morphogenetic protein 2 (BMP-2) added to the medium
18 ential delivery of essential growth factors, bone morphogenetic protein 2 (BMP-2) and vascular endoth
21 determining role of these residues, BG bound bone morphogenetic protein 2 (BMP-2) weakly or not at al
24 study, we discovered the double deletion of bone morphogenetic protein 2 (Bmp2) and bone morphogenet
28 e previously identified a nuclear variant of bone morphogenetic protein 2 (BMP2), named nBMP2, that i
30 GO with the growth factor recombinant human bone morphogenetic protein 2 (rhBMP-2), producing a scaf
33 ptide nanostructures amplified signalling of bone morphogenetic protein 2 significantly more than the
35 les, histochemical, and immunohistochemical (bone morphogenetic protein 2/4 [BMP2/4], osteocalcin [OC
36 rently, sustained in vivo delivery of active bone morphogenetic protein-2 (BMP-2) protein to responsi
37 ch as fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 (BMP-2) work synergisticall
39 gulates differentiation of OCs downstream of bone morphogenetic protein-2 (BMP-2)-stimulated osteobla
40 l with a collagen scaffold soaked in saline, bone morphogenetic protein-2 (BMP-2; 200 ng), 1 muM CGS2
41 al and temporal release of recombinant human bone morphogenetic protein-2 (BMP2) and vascular endothe
43 on of mesenchymal stem cells (MSCs), whereas bone morphogenetic protein-2 (BMP2) promotes osteogenic
45 In osteoblasts, CypA is necessary for BMP-2 (Bone Morphogenetic Protein-2)-induced Smad phosphorylati
46 tor (RUNX)-2, integrin binding sialoprotein, bone morphogenetic protein-2, osteocalcin, and cementum
49 n of bone morphogenetic protein 2 (Bmp2) and bone morphogenetic protein 4 (Bmp4) in the dental epithe
50 response to transient (24-36 h) exposure to bone morphogenetic protein 4 (BMP4) plus inhibitors of A
51 coprotein 1 (GLG1) expression and downstream bone morphogenetic protein 4 (BMP4) signaling and also r
52 es different concentrations of activin A and bone morphogenetic protein 4 (BMP4) to polarize cells in
53 peri-gastrulation-like fate patterning upon bone morphogenetic protein 4 (BMP4) treatment of geometr
60 le protocol, using defined medium containing bone morphogenetic protein 4 by which human pluripotent
62 e, miR-18a decreased the expression of BMP4 (bone morphogenetic protein 4) and HIF-1alpha (hypoxia-in
66 es for hESC differentiated to TB by means of bone morphogenetic protein-4 and inhibitors of activin A
67 t Six1 and Six2 regulate both endothelin and bone morphogenetic protein-4 signaling pathways to patte
70 Recent work has suggested that increased bone morphogenetic protein 6 (BMP6) expression could alt
73 ether these molecules intersect in vivo with bone morphogenetic protein 6 (BMP6)/mothers against deca
76 ansforming growth factor beta (TGFbeta), and bone morphogenetic protein 7 (BMP7), CD1c(+) dendritic c
79 VEGF-A, VEGF-C, VEGF-D, VEGF-A isoform 121, bone morphogenetic protein 7, macrophage colony-stimulat
81 (drMM) in the presence of human recombinant bone morphogenetic protein 7/human recombinant fibroblas
82 hat supplementation of exogenous recombinant bone morphogenetic proteins 7 effectively ameliorates en
83 echanisms involved revealed the induction of bone morphogenetic protein-7 (BMP7) expression, a critic
85 cluding fibroblast growth factor 21 (FGF21), bone morphogenetic protein 8b (BMP8b), growth differenti
86 d endothelial cell signalling in response to bone morphogenetic protein 9 (BMP9) and BMP10 is of sign
89 T is caused by loss-of-function mutations in bone morphogenetic protein 9 (BMP9)-ALK1-Smad1/5/8 signa
92 recipitation-sequencing experiments on BMP9 (bone morphogenetic protein 9)-stimulated endothelial cel
96 Our objective is to determine circulating Bone morphogenetic protein-9(BMP-9) levels in subjects w
99 otein negatively regulates the activities of bone morphogenetic protein and phosphoinositide 3-kinase
100 To address whether elevated activities of bone morphogenetic protein and PI3K/AKT signaling pathwa
101 valves demonstrated activation of canonical bone morphogenetic protein and Wnt/beta-catenin signalin
102 ntiation and new bone formation through WNT, bone morphogenetic protein, and Notch signaling pathways
103 ation of Hedgehog, fibroblast growth factor, bone morphogenetic protein, and Wnt signaling in the gen
104 , Indian hedgehog, fibroblast growth factor, bone morphogenetic protein, and Wnt signaling pathways i
105 cardiogenic fate of CNC(kit) is regulated by bone morphogenetic protein antagonism, a signaling pathw
107 ase inhibitors, activin traps, hepcidin, and bone morphogenetic protein antagonists in treating cance
110 itions and vascular calcification, including bone morphogenetic protein (BMP) and transforming growth
112 t in the context of reduced ShcA levels, the bone morphogenetic protein (BMP) antagonist chordin-like
114 cted gene aberrant in neuroblastoma (DAN), a bone morphogenetic protein (BMP) antagonist we detected
115 e that CHRDL1 encodes Ventroptin, a secreted bone morphogenetic protein (BMP) antagonist, the molecul
119 evelopment, with a classic example being the bone morphogenetic protein (BMP) gradient's conserved ro
121 iron homeostasis by direct interaction with bone morphogenetic protein (BMP) ligands to induce hepci
122 that injury stimulates the production of two bone morphogenetic protein (BMP) ligands, Dpp and Gbb, w
123 equencing (ChIP-seq) data, we identified the bone morphogenetic protein (BMP) pathway as a potential
127 in particular the dual modulation of Wnt and bone morphogenetic protein (BMP) pathway signaling, this
128 on the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) pathway, which is one o
132 its surrogate surface marker P2RY1, and the bone morphogenetic protein (BMP) receptor 1A (BMPR1A)/ac
134 ated that OA-MSC expressed the same level of Bone Morphogenetic Protein (BMP) Receptor-1A as OAC but
136 ransforming growth factor beta (TGFbeta) and bone morphogenetic protein (BMP) signal transduction in
137 red neogenic hair follicles, which triggered bone morphogenetic protein (BMP) signaling and then acti
138 cal and genetic epistasis studies identified bone morphogenetic protein (BMP) signaling as a mediator
140 We showed previously that SMOC inhibits bone morphogenetic protein (BMP) signaling downstream of
141 Loss of the growth-suppressive effects of bone morphogenetic protein (BMP) signaling has been demo
142 mice were carried out to assess the role of bone morphogenetic protein (BMP) signaling in psoriatic
143 lly cryptic "secondary cells." Inhibition of bone morphogenetic protein (BMP) signaling in secondary
144 result of differential regulation of Wnt and bone morphogenetic protein (BMP) signaling in these two
146 has been constructed and, here, we show that bone morphogenetic protein (BMP) signaling is essential
149 function of an activity-dependent autocrine Bone Morphogenetic Protein (BMP) signaling pathway at th
151 ibit Ras signaling and may also activate the bone morphogenetic protein (BMP) signaling pathway in co
152 coagulation factor fibrinogen activates the bone morphogenetic protein (BMP) signaling pathway in ol
155 rates that RNAi silencing of a member of the Bone Morphogenetic Protein (BMP) signaling pathway, Deca
156 f these mutants target the components of the Bone Morphogenetic Protein (BMP) signaling pathway, reve
158 axis is established and patterned by Wnt and bone morphogenetic protein (BMP) signaling pathways, res
159 e through modulation of Hedgehog, Notch, and bone morphogenetic protein (BMP) signaling pathways.
162 between transforming growth factor beta1 and bone morphogenetic protein (BMP) signaling plays an impo
166 y element-binding protein (SREBP) signaling, bone morphogenetic protein (BMP) signaling, and glycosyl
167 SMAD1/5 transcription factors, activated by bone morphogenetic protein (BMP) signaling, are major re
168 Multiple invasion pathways including EMT, bone morphogenetic protein (BMP) signaling, chemokine si
170 elf-renewing SCs, Foxc1 activates Nfatc1 and bone morphogenetic protein (BMP) signaling, two key mech
171 per, notable for roles in Wingless (Wnt) and bone morphogenetic protein (BMP) signaling, were differe
178 nd transforming growth factor-beta (TGFbeta)/bone morphogenetic protein (BMP) signalling and illustra
179 wingless-related integration site (WNT), and bone morphogenetic protein (BMP) signalling interactions
180 es from a murine myeloma model, we find that bone morphogenetic protein (BMP) signalling is upregulat
181 n coupled fibroblast growth factor (FGF) and bone morphogenetic protein (BMP) signalling together wit
182 s myocardial trabeculation through Erbb2 and bone morphogenetic protein (BMP) signalling, we discover
184 pression and signaling are up-regulated, and bone morphogenetic protein (BMP) signals are impaired.
186 and Wnt/beta-catenin) or share (TGFbeta and bone morphogenetic protein (BMP)) core signaling compone
187 wingless-integrated site (Wnt)/beta-catenin, bone morphogenetic protein (Bmp), and fibroblast growth
189 ys, epidermal growth factor receptor (EGFR), bone morphogenetic protein (BMP), Jun kinase (JNK), JAK/
190 dels commonly increase signaling of the Wnt, bone morphogenetic protein (BMP), or Ras/ERK pathways, c
191 FE) is specified by sequential inhibition of bone morphogenetic protein (BMP), transforming growth fa
192 ial cells (recell-dTBs); 3) dTBs seeded with bone morphogenetic protein (BMP)-2 (dTB-BMPs); and 4) fr
194 owth factor (TGF)-beta family, TGF-beta1 and bone morphogenetic protein (BMP)-2, in synovial fibrobla
195 s of inducible nitric oxide synthase (iNOS), bone morphogenetic protein (BMP)-2, matrix metalloprotei
196 nd that iSMCs from HGPS donors overexpressed bone morphogenetic protein (BMP)-4, which plays a key ro
199 receptor and function as coreceptors for the bone morphogenetic protein (BMP)/growth differentiation
201 ad2/3 pathway and activation of the parallel bone morphogenetic protein (BMP)/Smad1/5 axis (recently
202 was accompanied by changes in expression of bone morphogenetic protein (BMP)/sons of mothers against
204 es the gene encoding hepcidin (HAMP) via the bone morphogenetic protein (BMP)6 signaling to SMAD.
207 f CR-CSCs to chemotherapy and the ability of bone morphogenetic proteins (BMP) to promote colonic ste
210 decapentaplegic (dpp), the homolog of human bone morphogenetic proteins BMP2 and BMP4, is a muscle-s
212 d that mutations in the type II receptor for bone morphogenetic protein (BMPRII) underlie the majorit
214 glands are specified by mesenchymal-derived bone morphogenetic proteins (BMPs) and fibroblast growth
226 the K19/14 sites in the promoter regions of bone morphogenetic proteins (BMPs) genes, which were ass
227 trauma with an osteo-inductive agent such as bone morphogenetic proteins (BMPs) has been considered a
228 gnaling involves binding to and sequestering bone morphogenetic proteins (BMPs) in the extracellular
230 rcomes the inhibitory effect of lung-derived bone morphogenetic proteins (BMPs) on self-renewal and t
234 anoid cultures, such as those involving Wnt, bone morphogenetic proteins (BMPs), Notch, and Hedgehog
235 ignaling by Sonic hedgehog (SHH) followed by Bone morphogenetic proteins (BMPs), regulate a dynamic e
238 operate locally (e.g., Wingless/Ints [Wnts], Bone Morphogenetic Proteins [BMPs], and Hedgehogs [Hhs])
239 channels regulate release of the Drosophila bone morphogenetic protein Dpp in the developing fly win
240 ignaling pathways, including Sonic hedgehog, bone morphogenetic protein, fibroblast growth factor, tr
241 Decapentaplegic, a homolog of the vertebrate bone morphogenetic protein) from the wing imaginal disc.
244 ilarly, wild-type (WT) animals, in which the bone morphogenetic protein-mothers against decapentapleg
245 niche signalling pathways, specifically Wnt, bone morphogenetic protein, Notch and epidermal growth f
247 GDF7 (rs3072), which encodes a ligand in the bone morphogenetic protein pathway, and TBX5 (rs2701108)
248 We analyzed the effect of Irf8 on TGF-beta/bone morphogenetic protein pathway-specific genes in DCs
249 /or cocaine due to severe down-modulation of bone morphogenetic protein receptor (BMPR) axis: the ant
250 ce suggests that serotonin, mutations in the bone morphogenetic protein receptor (BMPR) II gene, and
251 e mutations leading to reduced expression of bone morphogenetic protein receptor (BMPR) II, these mut
252 Monoallelic mutations in the gene encoding bone morphogenetic protein receptor 2 ( Bmpr2) are the m
254 Because decreased expression and function of bone morphogenetic protein receptor 2 (BMPR2) is observe
255 terized by endothelial dysfunction, impaired bone morphogenetic protein receptor 2 (BMPR2) signaling,
256 hat in SMC and EC contact cocultures, BMPR2 (bone morphogenetic protein receptor 2) is required by bo
257 with hyperactivating mutations of the type I bone morphogenetic protein receptor ACVR1 (Activin type
258 However, transforming growth factor beta and bone morphogenetic protein receptor II signaling, and hy
259 role of transforming growth factor beta and bone morphogenetic protein receptor II signaling, human
260 ifferential transforming growth factor beta, bone morphogenetic protein receptor II signaling, or car
262 tion of SMAD1 by activin A receptor type 1L, bone morphogenetic protein receptor type 1A, and bone mo
263 morphogenetic protein receptor type 1A, and bone morphogenetic protein receptor type 1B and phosphor
265 erozygous mutations in the gene encoding the bone morphogenetic protein receptor type 2 (BMPR2) are t
266 ith heritable PAH caused by mutations in the bone morphogenetic protein receptor type 2 (BMPR2) gene
267 l hypertension with germline mutation in the bone morphogenetic protein receptor type 2 (BMPR2) gene,
268 despite clinical and molecular similarity to bone morphogenetic protein receptor type 2 mutation-asso
272 duced aggregation; 2) rs11202221, in BMPR1A (bone morphogenetic protein receptor type1A), replicated
273 sed to track the expression of a manipulated bone morphogenetic protein receptor within the Brainbow
274 in accumulation of synaptic growth-promoting bone morphogenetic protein receptors in the cell body an
275 s of VBA, with and without recombinant human bone morphogenetic protein (rhBMP)-2, under space-making
278 G85R) We found cell-autonomous activation of bone morphogenetic protein signaling in proprioceptor se
279 ith our demonstration that the activation of bone morphogenetic protein signaling in proprioceptors a
281 (Wnt), transforming growth factor-beta, and bone morphogenetic protein signaling pathways affect car
282 rse transcriptional programs associated with bone morphogenetic protein signaling, alveolar specifica
283 R/MEK/Erk1/2 signaling and downregulation of bone morphogenetic protein signaling, with negative and
286 dysregulated transforming growth factor beta/bone morphogenetic proteins signaling and that this imba
287 ing, and that ligandless activity in the TGF/bone morphogenetic proteins signaling pathway contribute
289 tor cyclin-dependent kinase 1 decreases BMP (bone morphogenetic protein) signaling activity specifica
291 ay), and that they activate cardioprotective bone-morphogenetic-protein signalling in cardiomyocytes.
293 showed that loss of PEAT modestly increases bone morphogenetic protein target gene expression and al
294 es with sLR11 inhibits thermogenesis via the bone morphogenetic protein/TGFbeta signalling pathway an
295 fferentially expressed genes were related to bone morphogenetic protein type 2 receptor (BMPR2) signa
296 ty of HPAH patients inherit mutations in the bone morphogenetic protein type 2 receptor gene (BMPR2),
297 DNA damage and impaired signaling of BMPR2 (bone morphogenetic protein type 2 receptor) via two down
299 Heterozygous germ-line mutations in the bone morphogenetic protein type-II receptor (BMPR-II) ge