ライフサイエンスコーパス: bone tissue

1 ), gadolinium was detected in human cortical bone tissue.

2 ercome the challenge of forming vascularized bone tissue.

3 mechanical loads distributed throughout the bone tissue.

4 with the repair and regeneration of missing bone tissue.

5 itulate this stepwise differentiation toward bone tissue.

6 h and Bmp4 synergize to promote expansion of bone tissue.

7 and enhance, the formation of de novo mature bone tissue.

8 localised pH levels in osteocytic lacunae in bone tissue.

9 collagens and is expressed predominantly in bone tissue.

10 ession directly correlated with proximity to bone tissue.

11 eplicate these definitive characteristics of bone tissue.

12 development of cerebellar Purkinje cells and bone tissue.

13 e, the major mineral component of vertebrate bone tissue.

14 cus that modulates the mechanosensitivity of bone tissue.

15 als must be large in order to be anabolic to bone tissue.

16 gher in several tissues, including tumor and bone tissue.

17 r histological analysis of the treated human bone tissue.

18 t some part of the implant is not covered by bone tissue.

19 ft material for residual particle content in bone tissue.

20 suffer from a general loss of fat, lean, and bone tissue.

21 activity was associated with the subchondral bone tissue.

22 en fiber birefringence intensity in alveolar bone tissue.

23 atio mimicking the natural structure of soft bone tissue.

24 low critical levels that can cause damage to bone tissue.

25 lar development and its integration with the bone tissue.

26 1700 nm for in-depth imaging of tumorous and bone tissue.

27 to bone surfaces is important for remodeling bone tissue.

28 asts are unique in their capacity to degrade bone tissue.

29 nslated to study the highly mechanosensitive bone tissue.

30 95% CI, 2.4 to 37.4) compared with unexposed bone tissue.

31 triggers the pyroptosis response in diabetic bone tissue.

32 , as well as for physiological remodeling of bone tissue.

33 maining bone region developed higher density bone tissue.

34 important cellular and molecular aspects of bone tissue.

35 been reported to affect the regeneration of bone tissue.

36 o calculate an estimated distribution of the bone tissue.

37 he low proton density and fast decay time of bone tissue.

38 ell driver mutations needed for invading the bone tissue.

39 antly more labile than in the case of mammal bone tissues.

40 was identified in CXCR4-deficient cells and bone tissues.

41 clasts numbers were increased in subchondral bone tissues.

42 y PTH in several osteoblastic cell lines and bone tissues.

43 l cells and the invasion of tumor cells into bone tissues.

44 th remains insufficient, particularly within bone tissues.

45 pic and likely mediate their effects via non-bone tissues.

46 s and quantification errors in the lungs and bone tissues.

47 A osteochondral (i.e., cartilage-subchondral bone) tissues.

48 TP were widely present in bone tissues adjacent to the implant surface, particular

49 jaw) nor pathology (healthy vs necrotic jaw bone tissue) affected the averaged spectral shape of the

50 istent level of approximately 10(7) CFU/gram bone tissue after day 7.

51 to restore the mechanical environment of the bone tissue after it has been perturbed by ovariectomy.

52 Timely harvesting of bone tissue after tumor cell injection and intravital bo

53 Bone-tissue analyses showed reduced tissue mineral densi

54 he pediatric atlas showed a reduced error in bone tissue and better delineation of bone structure.

55 C exhibited a similar microstructure to the bone tissue and contained rhBMP-2.

56 PC-3MM2 cells growing adjacent to bone tissue and endothelial cells within these lesions e

57 is characterized by the presence of necrotic bone tissue and increased osteoclast activity.

58 by a decrease in the density and quality of bone tissue and is associated with substantial morbidity

59 sease that is characterized by overgrowth of bone tissue and is linked to mutations in the gene encod

60 RIN3 was expressed in bone tissue and its expression level was approximately 1

61 ovarian parenchyma to be mostly replaced by bone tissue and seminiferous tubule-like structures.

62 steoblasts to deposit structural mineralized bone tissue and subsequently acquire the resting-state b

63 phorus and calcium signals representing hard bone tissue and sulfur distribution representing soft ti

64 due to the relatively low vascularization of bone tissue and the presence of physical barriers.

65 pid, simultaneous visualisation of calcified bone tissue and the vasculature within the calcified bon

66 oCell formulations resulted in pathogen-free bone tissues and implants in 9 of 12 and full eradicatio

67 hat possess estrogen agonist-like actions on bone tissues and serum lipids while displaying potent es

68 in various pathological conditions affecting bone tissues and the bone microenvironment, including rh

69 nitors in the fetal BM contribute to nascent bone tissues and transient stromal cells that are replac

70 tatin (ATV) has shown pleiotropic effects on bone tissue, and osteoporosis can aggravate periodontiti

71 hyrin I isomer accumulation in erythrocytes, bone, tissues, and excreta and had fluorescent erythrodo

72 tion coefficient of 0.143 or 0.151 cm(-1) to bone tissue appears to give the best trade-off between b

73 Vascular malformations that occur inside bone tissue are rare.

74 Bone tissues are the main metastatic sites of many cance

75 Bone tissue arises from mesenchymal cells induced into t

76 dy is to analyze the tension distribution on bone tissue around implants with different angulations (

77 Stress patterns in the bone tissue around the implant were analyzed qualitative

78 ing, invasion, and growth of cancer cells in bone tissue as well as genes important for osteolysis, i

79 regulation of cell proliferation within the bone tissue as well as properties of the extracellular m

80 were associated with deleterious effects in bone tissue, as evidenced by a lower number of osteocyte

81 ually and are replaced by highly matured new bone tissues, as assessed by image-based analyses (X-ray

82 The loss of alveolar bone tissue associated with periodontal disease appears

83 suggest that incorrectly accounting for the bone tissue attenuation can lead to large underestimatio

84 o soft tissue resulting in smaller volume of bone tissue available for remodeling.

85 and how the gene defects impact on skin and bone tissues besides than on the haematological compartm

86 Recent advancements in bone tissue biomarker research have identified 2 promisi

87 ow giantin impacts the production of healthy bone tissue by focusing on the main protein component of

88 ape immune surveillance and metastasize into bone tissue by inducing osteoclastic bone resorption.

89 Destruction of bone tissue by osteoclasts represents a severe pathologi

90 tor cells (BM-MSPCs) maintain homeostasis of bone tissue by providing osteoblasts.

91 Bone tissue, by definition, is an organic-inorganic nano

92 It is known that the bone tissue can serve as a gadolinium depot, but so far

93 enzyme phosphoglycerate kinase (PGK) inside bone tissue cells as a function of temperature from 38 t

94 More donor cells were found in bone tissues compared with other organs (P < .001), with

95 ered model is described here that reproduces bone tissue complexity and bone remodeling processes wit

96 Alterations in bone tissue composition during osteoporosis likely disru

97 tical for crosslinking is reduced in proband bone tissue, consistent with decreased lysyl hydroxylase

98 aside from the joint pannus, the subchondral bone tissue constitutes an essential element in the deve

99 Delivery of therapeutic stem cells to treat bone tissue damage is a promising strategy that faces ma

100 The magnitude and mode of bone tissue deformation that elicits a transcriptional r

101 Expressed in bone tissue, dental pulp stem cells, and periodontal lig

102 ne modeling, a process of coordinated, local bone-tissue deposition and removal that keeps bone strai

103 stigate the effect of biodegradation rate on bone tissue development in vivo.

104 treatment of the defect site with autologous bone tissue did not improve bone formation or defect bri

105 Femoral head trabecular bone tissue digests were sorted into CD45-CD271+CD56+CD1

106 Unirradiated bone tissue displayed the presence of Mn(2+) ions at bot

107 f predominantly parallel-fibered or lamellar bone tissue during middle-late ontogeny.

108 l Runx2 for the formation of intramembranous bone tissues during embryogenesis.

109 turing processes used to create regenerative bone tissue engineered implants are not biocompatible, t

110 roaches to fabrication of nSC composites for bone tissue engineering (BTE) have limited capacity to a

111 for being used as biodegradable implants in bone tissue engineering (BTE), owing to their suitable b

112 cal settings that need to be addressed using bone tissue engineering (BTE).

113 Bone tissue engineering aims to harness materials to dev

114 hybrid system (CM-ALs) for drug delivery and bone tissue engineering application.

115 lymer, has established a good reputation for bone tissue engineering applications due to its many uni

116 For bone tissue engineering applications, tissue collection

117 of graphene/nano-58S composite scaffold for bone tissue engineering applications.

118 ) (PLAGA) sintered microsphere scaffolds for bone tissue engineering applications.

119 provide controlled biochemical delivery for bone tissue engineering applications.

120 esents an exciting property for their use in bone tissue engineering applications.

121 el allows for evaluation of biomaterials and bone tissue engineering approaches within a reproducible

122 e is a growing need for the investigation of bone tissue engineering approaches within contaminated o

123 stimulate repair of demineralized dentin and bone tissue engineering are also addressed.

124 Current approaches in bone tissue engineering are restricted by delayed vascul

125 This study instituted a unique approach to bone tissue engineering by combining effects of mechanic

126 Although most in vivo work in the area of bone tissue engineering focuses on bone regeneration wit

127 Substantial progress has been made in bone tissue engineering in recent years, based on the re

128 A key tenet of bone tissue engineering is the development of scaffold m

129 ility and poor functional vascularization in bone tissue engineering lead to lack of tissue integrati

130 ial enabling technology to translate generic bone tissue engineering methods into specific solutions

131 Fibrous scaffolds are used for bone tissue engineering purposes with great success acro

132 ng exploited together with growth factors as bone tissue engineering scaffolds regulating cell behavi

133 SORS) for nondestructive characterization of bone tissue engineering scaffolds.

134 ition, which has relevance for the design of bone tissue engineering strategies and may inform clinic

135 g candidate as a safe, efficacious pediatric bone tissue engineering strategy.

136 be used to develop therapeutic strategies in bone tissue engineering with numerable clinical applicat

137 For bone tissue engineering, a number of small animal models

138 nces in segmental bone defect animal models, bone tissue engineering, and drug delivery with the goal

139 rovascularized characteristics over BMP-2 in bone tissue engineering, is highlighted, which lays the

140 autograft and BMP products used commonly in bone tissue engineering.

141 -induced pluripotent stem cells (hiPSCs) for bone tissue engineering.

142 e interest for their use as cell carriers in bone tissue engineering.

143 ted on hUCMSC encapsulation in scaffolds for bone tissue engineering.

144 al processes for implant osseointegration or bone tissue engineering.

145 for fabrication of 3D scaffolds intended for bone tissue engineering.

146 CM-ALs (10%) scaffolds for drug delivery and bone tissue engineering.

147 25(OH)D3 has great potential for cell-based bone tissue engineering.

148 njugated NDs to develop a novel platform for bone tissue engineering.

149 be considered as an appealing candidate for bone tissue engineering.

150 al-control release systems that are used for bone tissue engineering.

151 lly allow us to achieve the ultimate goal of bone tissue engineering: to reconstruct entire bones wit

152 with applications in cementitious materials, bone-tissue engineering, drug delivery and refractory ma

153 iation of MSCs with profound implications on bone-tissue-engineering applications.

154 The OR associated with bone tissue exposed to 1-4 Gy was 4.8-fold (95% CI, 1.2

155 Obtaining frozen sections of bone tissue for intraoperative examination is challengin

156 ely used by orthopedic surgeons to stimulate bone tissue formation alone and when paired with biomate

157 T-MSCs, both cells had the ability to induce bone tissue formation at comparable amounts and properti

158 the human bone core biopsies revealed normal bone tissue formation identical to the surrounding nativ

159 hanism, suggesting a new strategy to promote bone tissue formation in osteoporotic patients.

160 he capability of developed microcarriers for bone tissue formation was examined in vivo.

161 Therefore, the capacity for rapid bone tissue formation, a derived aspect of rapid growth

162 All scaffolds promoted bone tissue formation, with the carbon-graphene scaffold

163 est a central role for WWOX in regulation of bone tissue formation.

164 er to mimic the natural microenvironment for bone tissue formation.

165 erentiation of stem and progenitor cells and bone tissue formation.

166 eful diagnostic information regarding intact bone tissue fragments from surgical excision or biopsy s

167 elevancy of these findings in infected human bone tissue from patients with S. aureus-associated oste

168 er X-ray control, to obtain non-contaminated bone tissue from which we extracted ancient DNA (aDNA) u

169 o displayed high translational potential for bone tissue generation.

170 At distinct anatomical sites, bone tissue harbors multiple types of skeletal stem cell

171 rmine occupancy of Cathepsin K inhibitors in bone tissues harvested from rabbit femurs.

172 Bone tissue has the capacity to adapt to its functional

173 tural and therapeutic effects for example in bone tissue healing and ageing.

174 ntly, cartilage ECM could not generate frank bone tissue if devitalized by standard "freeze & thaw" (

175 s a chaotic architecture of dense apneumatic bone tissue in all three taxa.

176 de (FF-XANES) at the calcium K-edge on human bone tissue in healthy and diseased conditions and for d

177 are found in hyaline cartilage in the adult, bone tissue in newborn mice, and osteoblasts and associa

178 anipulation of cancer cell interactions with bone tissue in real time.

179 GE was expressed at higher levels in healing bone tissues in diabetic compared to control animals.

180 . aureus pathogenesis and persistence within bone tissue, including implant-associated biofilms, absc

181 omography (sDECT) images to provide accurate bone tissue information.

182 to identify late stages of the disease, when bone tissue is affected.

183 ect PET quantification in these regions when bone tissue is ignored.

184 In the human body, bone tissue is in a state of constant balance of product

185 e mechanism of gadolinium incorporation into bone tissue is not fully understood and requires spatial

186 Imbalanced bone tissue is observed in mutant mice combining reduced

187 A paradox in bone tissue is that tissue-level strains due to animal a

188 G laser, despite producing thermal damage to bone tissue, is comparable to that with conventional dri

189 eover, aP2-Cre-mediated ACC1 inactivation in bone tissue led to a decreased number of osteoblasts but

190 In vitro, co-culture of PC3 cells with bone tissue led to activation of pro-MMP-9 and increases

191 The total numbers of soft-tissue and bone-tissue lesions, in a site-by-site comparison, were

192 ifferences in the fracture resistance at the bone tissue level.

193 At the bone-tissue level, acidosis was associated with deficits

194 e report the presence of endosteally derived bone tissues lining the interior marrow cavities of port

195 e 10 were distinct from BW, lean tissue, and bone tissue loci.

196 to CT-based attenuation maps for regions of bone tissue, lungs, and soft tissue.

197 at: 1) the oblique load was more damaging to bone tissue, mainly when associated with external hexago

198 he bone glue that acts as a scaffold between bone tissues matrix composition to bind them together an

199 d yield critical information on cellular and bone tissue mechanisms and translate to new mechanistic

200 An integrOmics approach of source-matched bone tissue metabolome and bone marrow RNA sequencing in

201 Bone tissue metabolome indicated enrichment in metabolit

202 valuated histologically, and the subchondral bone tissue microarrays (TMAs) were subsequently manuall

203 tial organization and interactions in native bone tissue microenvironment is crucial for advancing pr

204 mal mineralization of the collagen matrix of bone, tissue-nonspecific alkaline phosphatase (TNAP) is

205 in was determined in articular cartilage and bone tissue obtained from mice, rats, and human subjects

206 model, efficiently remodeled to form de novo bone tissue of host origin, including mature vasculature

207 tified: participants with loss of supporting bone tissue of less than one third of the root length (B

208 in <30% of teeth (BL), or loss of supporting bone tissue of one third or more of the root length in >

209 of the root length (BL-), loss of supporting bone tissue of one third or more of the root length in <

210 l-1 is increased approximately 4-fold in the bone tissues of GILZ transgenic (Tg) mice, and this incr

211 ion of MSCs into osteoblasts laying down new bone tissue on orthopedic implants.

212 eural crest development: 1) disagreements in bone tissue origin within and across current model syste

213 In healthy bone tissue, osteocytes experience higher maximum strain

214 to assess chemical properties of Ca in human bone tissue our data suggest that neither the anatomical

215 hows a higher tendency to stay intact in the bone tissues over time, while a GBCA with a linear ligan

216 ficantly higher stress concentrations in the bone tissue (P <0.05) compared with the tapered connecti

217 metastatic bone lesions and normal-appearing bone tissue (P <= .02).

218 rved an almost complete normalization of all bone tissue parameters, using radiographic, microcompute

219 microscopy may allow for rapid diagnoses of bone-tissue pathologies and aid the intraoperative deter

220 in single amino-acid position for particular bone tissue pathology.

221 Net MMP-9 activity in bone tissues peaked 2 weeks after injection, coinciding

222 rkca(-/-) female but not male mice, in which bone tissue progressively invades the medullary cavity i

223 there is uncertainty regarding the risks of bone tissue radiation doses below 10 Gy and the dose-res

224 hymal stromal cells (MSCs) could be used for bone tissue regeneration as tissue engineered periosteum

225 The goal of this study was to improve bone tissue regeneration by using targeted GNPs.

226 Biomaterials for bone tissue regeneration represent a major focus of orth

227 Although bone tissue regeneration strategies involve culture of b

228 ters and have the potential to inform future bone tissue regeneration strategies that can optimize th

229 special attention for their ability to guide bone tissue regeneration through structural and biologic

230 t that OA is a promising bioactive agent for bone tissue regeneration, and inhibition of Notch signal

231 For bone tissue regeneration, the ability to bind Ca(2+) and

232 fold is a very promising approach to promote bone tissue regeneration.

233 P-1-p1 is an effective bioactive peptide for bone tissue regeneration.

234 ems can develop new strategies for improving bone tissue regeneration.

235 patterns (spatial) and trends (temporal) of bone tissue regeneration.

236 nthetic, off-the-shelf, cell-free option for bone tissue repair and restoration.

237 congenital defects that require large-scale bone tissue repair have few successful clinical therapie

238 ced the host cells to coordinate and promote bone tissue repair through paracrine effects.

239 eful tools for therapeutic cell delivery for bone tissue repair.

240 opological optimization for designing facial bone tissue replacements might improve current clinical

241 aurs, and in light of evidence that dinosaur bone tissue resembles the histology in mammals, the hist

242 f interest inside the lung, soft tissue, and bone tissue, respectively.

243 Bone tissues respond to mechanical loading/unloading reg

244 l results, however, histologic evaluation of bone tissue response to different hydration and incorpor

245 Inflammatory array for protein lysed from bone tissue revealed deletion of Ezh2 decreased inflamma

246 her, RNA sequencing analysis of regenerative bone tissue revealed that SHPP-ZB hydrogel promoted vasc

247 d the HyA staining of osteocytes in cortical bone tissue sections to the extent that the lacunocanali

248 ing with decreased numbers of osteoclasts in bone tissue sections.

249 Rather, microscopic analyses of the long-bone tissues show that dinosaurs grew to their adult siz

250 Intravital two-photon imaging of bone tissues showed that a potent S1P(1) agonist, SEW287

251 ntal ligament with Sharpey's fibers, and new bone tissue similar to native periodontal tissues.

252 s are formed by the apposition of periosteal bone tissue, similar to the growth of wood, and preserve

253 tors are key regulators of hematopoietic and bone tissue-specific gene expression.

254 lated transcriptional regulators to suppress bone tissue-specific genes during proliferative stages o

255 Developmental control of bone tissue-specific genes requires positive and negativ

256 3 (vitamin D)-induced transactivation of the bone tissue-specific osteocalcin gene.

257 Osteocalcin (OC) is known to be a bone tissue-specific protein, expression of which is bel

258 Bone tissue specimens were examined by light microscopy

259 e-forming cells, where it mediates brain and bone tissue stiffness by controlling expression of ECM c

260 antler, form and change rapidly, while other bone tissues, such as human tooth dentine, develop slowl

261 presence of apolipoprotein in demineralized bone tissue suggest the possibility that these particles

262 A cotylar internal plate of bone tissue sustains radial camellae (rad) in a conditio

263 In bone tissue SUV, SUVr and K(i) measures were not signifi

264 naling is adequate for mineralization of the bone tissue that does form.

265 erized by low bone mass and deterioration of bone tissue that leads to bone fragility and an increase

266 ed to distinct diseases involving adipose or bone tissue, the metabolic syndrome, and osteogenesis im

267 orders of magnitude below those that damage bone tissue, this anabolic, non-invasive stimulus may ha

268 Remarkably, EM-eNMs selectively target bone tissues through systemic delivery and significantly

269 The generation and homeostasis of bone tissue throughout development and maturity is contr

270 into the bone microenvironment, and destroy bone tissue to allow for tumor growth.

271 s to harness materials to develop functional bone tissue to heal 'critical-sized' bone defects.

272 ations depends on the ability of surrounding bone tissue to integrate with the surface of the device,

273 ometry were used to determine lean, fat, and bone tissue traits in a F(2) mouse population from a C57

274 ion within bone and determines tumor-induced bone tissue transformation.

275 ed side effects and be clinically useful for bone tissue transplantation.

276 s studies have demonstrated that engineering bone tissue using mesenchymal stem cells (MSCs) is feasi

277 tic method to estimate the mu map, including bone tissue using only MR information, is presented.

278 ossible to estimate the anatomic location of bone tissue using UTE sequences.

279 ry subtle spectral variations related to the bone tissue variations itself.

280 the dynamic bone structure, showing reduced bone:tissue volume ratio and trabecular number in FVIIIK

281 New bone tissue was formed that grew in mass and cellularity

282 -16% and -11% occurred for methods in which bone tissue was ignored (SEG1 and SEG2).

283 Bone tissue was implanted into established pouches on BA

284 al ligament at the coronal aspect of the new bone tissue was similar in the smaller lesions between t

285 In aged bone tissue, we previously observed pathological opening

286 Sharpey's fibers, periodontal ligament, and bone tissue were formed far above the notch placed at th

287 Sharpey's fibers, periodontal ligament, and bone tissue were formed far coronal to the notch at the

288 that contained BMP-2, similar volumes of new bone tissue were formed; however, the faster degrading h

289 ability of the radiation-induced radicals in bone tissue were investigated by means of both isotherma

290 ntal ligament with Sharpey's fibers, and new bone tissue were observed.

291 In the present study, iliac bone tissues were harvested from 21 patients with AIS (m

292 of irradiated frog Limnonectes macrodon leg bones tissue were studied by electron paramagnetic reson

293 ethod in every region of interest except for bone tissue, where it was lower than 4% and 6.75 times s

294 on excited autofluorescence (TPaF) images of bone tissue which capture the distribution of matrix (fi

295 scaffolds can be modulated to form humanized bone tissue, which was also able to support human HSC en

296 ow bone mass and structural deterioration of bone tissue with an increased susceptibility to fracture

297 t means of obtaining high-resolution maps of bone tissue with sufficient anatomic accuracy for, for e

298 -expressing BMSSCs (BMSSC-Ts) generated more bone tissue, with a mineralized lamellar bone structure

299 rosus and nucleus pulposus) by cartilage and bone tissues, with cells staining for markers of hypertr

300 r mesenchymal cells organize into trabecular bone tissue within the artery wall.