ライフサイエンスコーパス: both sexes

1 en, adolescent girls, and/or young children (both sexes).

2 model with Abeta pathology (hAPP-J20 mice of both sexes).

3 d ommatidia and in vivo from intact flies of both sexes.

4 parity-frailty relationship was similar for both sexes.

5 ale mice or younger adult Tmprss9-/- mice in both sexes.

6 expressing (SOM(+)) interneurons, in mice of both sexes.

7 ol is sufficient to promote risk aversion in both sexes.

8 Drd1a-iCre and Drd2-iCre transgenic rats of both sexes.

9 ed lead to similar patterns of senescence in both sexes.

10 fference in risk of 90-day mortality between both sexes.

11 arbohydrates are associated with CHD risk in both sexes.

12 ss-induced decrease in sucrose preference in both sexes.

13 colliculus (IC) of unanesthetized rabbits of both sexes.

14 cochlear preparations in neonatal rats from both sexes.

15 ertile compared with the highest tertile for both sexes.

16 y condition scores improved for all ages and both sexes.

17 FST), but prevented anxiety-like behavior in both sexes.

18 tes of (R,S)-ketamine can be prophylactic in both sexes.

19 contributed to the development of frailty in both sexes.

20 -potentiated cocaine-primed reinstatement in both sexes.

21 ynaptic integration in male rats and mice of both sexes.

22 sociation in mouse rods and analyzed mice of both sexes.

23 cited cognitive impairments in all tests, in both sexes.

24 shy cells in the cochlear nucleus of mice of both sexes.

25 g) synergistically reduced ethanol intake in both sexes.

26 els and S. aureus killing by murine BMN from both sexes.

27 interactions within the Imc, in barn owls of both sexes.

28 ever, restraint potentiated reinstatement in both sexes.

29 ypes in reproduction and social behaviors in both sexes.

30 ha)), which displayed reduced body length in both sexes.

31 dy mass index (18.5%) and smoking (16.6%) in both sexes.

32 development of rat hippocampal neurons from both sexes.

33 tic complexity of NBM cholinergic neurons in both sexes.

34 mice across young, middle, and old ages with both sexes.

35 de-offs between survival and reproduction in both sexes.

36 dely considered as a key memory modulator in both sexes.

37 strongly and similarly associated with HF in both sexes.

38 that target this system and show efficacy in both sexes.

39 lar cells of goldfish (Carassius auratus) of both sexes.

40 onmental change on the selection response in both sexes.

41 ombined MIA/HI insult in murine offspring of both sexes.

42 that pathway stimulation was reinforcing in both sexes.

43 genic wild-type and Chrna5 knock-out mice of both sexes.

44 it increased several signaling molecules in both sexes.

45 ever, elicited migration of macrophages from both sexes.

46 en hippocampal neurons cultured from rats of both sexes.

47 tured rat embryonic hippocampal neurons from both sexes.

48 th symptomatic and asymptomatic subjects for both sexes.

49 al root ganglion (DRG) neurons isolated from both sexes.

50 m, conjunctiva and, rarely, systemically) in both sexes.

51 c and depressive affective-like behaviors in both sexes.

52 onal maps in acute brain slices from mice of both sexes.

53 1079 children, aged 2-21 y, were created for both sexes.

54 etween GD and CVD events which is present in both sexes.

55 rasonic vocalizations (USVs) were altered in both sexes.

56 that results in comparable stress effects in both sexes.

57 specificity in controls approached 100% for both sexes.

58 s directly into offspring, to the benefit of both sexes.

59 e mouse guts at E10.5, E12.5, and E14.5 from both sexes.

60 on led us to retest the protection of PRF in both sexes.

61 in acute brain slices obtained from rats of both sexes.

62 omosome 8p23, as a strong candidate locus in both sexes.

63 ly in boys and lower levels of FEV(1)/FVC in both sexes.

64 lead to differences in lifespan extension in both sexes.

65 thereby delaying the GABA switch in pups of both sexes.

66 on/maintenance of E2-induced potentiation in both sexes.

67 by paclitaxel in WT and Tlr9 mutant mice of both sexes.

68 learning in 20 young healthy participants of both sexes.

69 he developing mouse brain and spinal cord of both sexes.

70 g stress-induced depressive-like behavior in both sexes.

71 eficits across multiple cognitive domains in both sexes.

72 nical HF risk prediction model is limited in both sexes.

73 d D2-MSNs modulate alcohol intake in rats of both sexes.

74 ciative recall (AR) in human participants of both sexes.

75 king memory task performed by individuals of both sexes.

76 sed in obese mice compared with lean mice of both sexes.

77 OR = 1.08; 95% CI: 1.04-1.11) in children of both sexes.

78 al activity in adolescent Long Evans rats of both sexes.

79 ion-sensing utricles of chickens and mice of both sexes.

80 lateral), and PM (posteromedial)) in mice of both sexes.

81 and multiexposure speckle imaging in mice of both sexes.

82 ta-cell endoplasmic reticulum (ER) stress in both sexes.

83 alue of genetic studies of puberty timing in both sexes.

84 mino acid content in Drosophila studies with both sexes.

85 cause of death was ischemic heart disease in both sexes: 71.7% among women versus 75.7% among men, P=

86 motor adaptation experiment with subjects of both sexes, account for short aftereffects and large sav

87 e in the proportion of studies that included both sexes across all nine disciplines, but in eight of

88 Both sexes also display similar patterns of age-related

89 Increases in prevalence were noted in both sexes and across age groups-most notably in women a

90 stained over the long term and remains so in both sexes and all age groups is uncertain.

91 laque and bleeding on probing (P < 0.001) in both sexes and also to WHR in women (P = 0.026) and men

92 quencing to profile >32,000 ACs from mice of both sexes and applied computational methods to identify

93 f ERalpha in GHRH neurons disrupts growth in both sexes and causes pubertal delay in females.

94 niche maintains GSCs in the distal gonad of both sexes and does so via two key stem cell regulators,

95 rrogate local LCIC circuits in adult mice of both sexes and found that input patterns are highly depe

96 Drive can achieve 98 to 100% in both sexes and full introduction was observed in small c

97 Here, we compared WT and GluA3 KO mice of both sexes and identified several important roles of Glu

98 Mortality reductions were equally noted in both sexes and in the white and black populations but we

99 even reversed neuropathic pain in rodents of both sexes and in two models of traumatic nerve injury.

100 mes of 22q11.2 mutant human fibroblasts from both sexes and mouse brains carrying a 22q11.2-like defe

101 s of NR on human skeletal muscle may include both sexes and potentially provide comparisons between y

102 euroanatomical alterations that were seen in both sexes and resemble those reported in humans.

103 tress did impair novel object recognition in both sexes and social preference in females.

104 till express p75NTR in adult mouse cortex of both sexes and that its activation is sufficient to dest

105 We suggest that the reproductive anatomy of both sexes and their lateral mating behavior coevolved.

106 44 human donors representing individuals of both sexes and three major ancestries.

107 Failure to include both sexes and to address age in mechanistic atheroscler

108 We sought to characterize this circuit in both sexes and to investigate its role in potential sex

109 e primary hippocampal neuronal cultures from both sexes and using structured illumination microscopic

110 Here, we used Ca(2+) imaging on mice from both sexes and whole-cell recordings on female mouse TID

111 lture isolated from neonatal rat cortices of both sexes and young male and female mice with oligodend

112 women = 20.4%-62.3% in 12 cohorts recruiting both sexes) and 15,383 incident cases of T2D over the 9-

113 with rising age) was absent in dominants of both sexes, and as a result, the fitness costs of senesc

114 animal atherosclerosis models do not examine both sexes, and even in those that do, well-powered dire

115 PN caused macrophage infiltration to DRGs in both sexes, and this infiltration was not affected by Tl

116 ession of immediate early genes in rat GC of both sexes, and with reduced amplitude of BLA-GC synapti

117 nervation of the Drosophila antennal lobe of both sexes as a genetic model of this question.

118 s all age groups, with the highest rates for both sexes being observed in the 95+ age group.

119 For healthy and unhealthy people of both sexes, both the 97.5th and 2.5th GFR percentiles ex

120 VCID impaired spatial memory in both sexes, but episodic-like memory in females only.

121 tion, which suppresses college enrollment in both sexes, but for different reasons.

122 diet alone impaired episodic-like memory in both sexes, but spatial memory in females only.

123 esis in multiple fish and amphibian species (both sexes) by applying sparse cell electroporation to t

124 imulated SE in slices of juvenile rat brain (both sexes) by pairing two-photon uncaging of glutamate

125 In human subjects of both sexes, cerebellar theta stimulation improved episod

126 man brain activity while human participants (both sexes) classified continuous stimulus sets into dis

127 premature avertable mortality from NCDs for both sexes combined declined -1.3% (95% UI -1.4 to -1.2)

128 By province, the PAF in both sexes combined ranged from 35.2% in Shanghai to 52.

129 ssociated with higher all-cause mortality in both sexes combined.

130 re 3.0%, 0.99%, and 0.04%, respectively, for both sexes combined.Conclusions: We observed a consisten

131 Human participants (both sexes) completed visual and auditory WM tasks while

132 We found that adolescent rats of both sexes consumed enough THC to trigger acute hypother

133 showing an enhanced response to sucrose, and both sexes consuming more sucrose, sucralose and high fa

134 > muscle > intestine > blubber > fur, and in both sexes coprostanol level (8.95-21.01% of E25s) was h

135 tion factor Pou4f1 in type I SGNs in mice of both sexes correlates with a synaptic location on the mo

136 1 777 800 firearm deaths at all ages and in both sexes could be avoided, including 1 028 000 deaths

137 than females throughout the study, although both sexes declined at a similar rate (~40% overall), wi

138 Four weeks post infection, Hu-NSG mice of both sexes developed left ventricular (LV) diastolic dys

139 ex development, we analyzed human fetuses of both sexes diagnosed with OSB between 11 and 15 weeks of

140 fic Drp1 activator in vivo Bbeta2 KO mice of both sexes display elongated mitochondria in neurons and

141 Surprisingly, however, BAT-Kiss1r KOs of both sexes displayed significantly lower BW and adiposit

142 Some SIT programs release both sexes due to the lack of genetic sexing strains or

143 than in women and runs a malignant course in both sexes, due to cardiac complications.

144 rced expiratory flow, midexpiratory phase in both sexes (e.g., boys in the highest lean body mass ind

145 us electrical activity in mouse cochlea from both sexes emerges within ISCs during the late embryonic

146 n of delay and reward information in humans (both sexes) engaged in choices.

147 from over 11,500 9- to 10-year-old children (both sexes) enrolled in the Adolescent Brain Cognitive D

148 While both sexes exhibit aggression, its neuronal underpinning

149 End-stage dSod1 (G85R) animals of both sexes exhibit severe motor deficits with clear dege

150 Adult offspring of both sexes exposed to + Nic exhibited elevated locomotor

151 ha-SR), which were then crossed with mice of both sexes, expressing ALS-linked gene mutants for TAR D

152 ent in subcutaneous fat in the hip region in both sexes; fatty infiltration of leg muscles in men, es

153 al ganglion cell survival in vivo in mice of both sexes following optic nerve crush injury.

154 creases were greater in MOF(1) than CF(1) in both sexes for all variables except glucose in males and

155 screened 300 mutants in Drosophila larvae of both sexes for defects in synaptic growth at the neuromu

156 ysis can cost-effectively screen probands of both sexes for methylation and FM mosaicism that may be

157 ephalography recordings from healthy humans (both sexes) for processes predictive of the aftereffect

158 ogic inhibition of Sult1e1 protected mice of both sexes from AKI, independent of the presence of sex

159 stem cell (GSC) regulation are the same for both sexes: GLP-1/Notch signaling from the mesenchymal d

160 Both sexes had similar rates of 30-day stroke (2.3% vs.

161 stantially sexually aroused and attracted to both sexes-has remained controversial among both scienti

162 We found Thap1 (C54Y/+) mice of both sexes have elevated extracellular striatal acetylch

163 e signatures contributing to obesity despite both sexes having similar gut microbiome characteristics

164 is question by comparing 7 mormyrid species (both sexes) having varied EOD duration.

165 asthma outcomes at 12 and 17 years of age in both sexes (hazard ratio = 2.15; 95% CI: 1.21-3.84).

166 and similarly associated with incident HF in both sexes, highlighting the similar importance of risk

167 ity in cerebellar slices from mature mice of both sexes, I identified a previously unrecognized, freq

168 sis of triglyceride storage and breakdown in both sexes identified a role for triglyceride lipase bru

169 males in 1999 to less than 0.2 per 1,000 for both sexes in 2017, but incidence rates more than double

170 Here, we used mice of both sexes in a model of repetitive mild/concussive clos

171 saliva, in 878 people aged 3 to 89 years of both sexes in a rural Ugandan population cohort.

172 st comparison of mating-responsive miRNAs in both sexes in any species.

173 vement in life expectancy slowed sharply for both sexes in England and Wales, and slowed more moderat

174 artery occlusion (tMCAO) in neonatal mice of both sexes in relation to blood-brain barrier permeabili

175 ot only different functional requirements of both sexes in the new environment but also rapid sex-spe

176 We used a preterm fetal sheep model using both sexes in twin 0.65 gestation fetuses that reproduce

177 dy affects whole-body triglyceride levels in both sexes, in males, we identify an additional role for

178 g and cell death in a model of SE in mice of both sexes, including wild-type and TrkB(Shc/Shc) mutant

179 ased active coping during swimming stress in both sexes, increased locomotion and reduced social inte

180 urther, pathway activation is reinforcing in both sexes, indicating that suppression of conditioned a

181 We find that, in NF1 mice of both sexes, inhibition increases strongly during the dev

182 eIF4E overexpression elevates translation in both sexes, it only increases microglial density and siz

183 ry and inhibitory mouse hippocampal neurons (both sexes), its chronic stimulation by LPS induces a se

184 Human participants of both sexes learned associations (AB pairs, either face-s

185 Finally, both sexes lever pressed to self-stimulate the IL-NAcSh

186 ention mirrored trends in binge outcomes for both sexes, limiting concerns about invariance.

187 tion of LVAD therapy increased over time for both sexes, LVAD implantation remains stably lower in wo

188 explore visual processing in vLGN of mice of both sexes, making comparisons to dLGN and SC for perspe

189 magnetoencephalography while human subjects (both sexes) monitored the orientation of a grating stimu

190 In both sexes, most c-Fos neurons were identified as excita

191 flecting a preference for having children of both sexes, much like the coupon collector's problem in

192 In midkine-a loss-of-function mutants of both sexes, Muller glia initiate the appropriate reprogr

193 pathway by which principal cells in the rat (both sexes) OB excite GCs by evoking potent nondepressin

194 nopyridine (4-AP) improves motor behavior in both sexes of a severe mouse model of SMA.

195 Here, using both sexes of conditional mutant mice, we discovered tha

196 Both sexes of HFD-Hhip +/+ mice developed impaired gluco

197 Here, we report using both sexes of mouse that acute genetic knock-out of the

198 Both sexes of zebrafish were analyzed.

199 review highlights the importance of studying both sexes, of understanding sex differences (and simila

200 Experiments were conducted with both sexes, or with either sex.

201 n of an inhibitory avoidance task in mice of both sexes over an extended period of time and with thou

202 Inpatient mortality decreased for both sexes over time after LVAD, with a sharp fall in 20

203 ch block were strongly associated with HF in both sexes (p < 0.001), and the combined clinical model

204 ly increased with age to a similar extent in both sexes (P < 0.05), whilst MU firing rate progressive

205 mponent "figures." Naive human participants (both sexes) passively listened to these signals while pe

206 o this end, 32 healthy human participants of both sexes performed a cue-informed go/nogo task compris

207 ly-adaptive.Twenty-eight human participants (both sexes) performed a learning task while undergoing f

208 Humans (both sexes) performed a novel variable-choice task where

209 from human visual cortex while participants (both sexes) performed a rapid sequential visual search t

210 Here, we demonstrate that the mouse SC of both sexes plays a causal role in visual perceptual deci

211 Sixteen healthy volunteers of both sexes rated pain due to intraepidermal injections o

212 activity was measured as human participants (both sexes) read three-sentence scenarios.

213 an acute energy substrate crisis from which both sexes recovered within 24 h.

214 In both sexes, relapse after food choice-induced abstinence

215 ed negative valence behaviors in SUS mice of both sexes relative to RES and CNTRL mice.

216 cytes-specific deletion of N-Wasp in mice of both sexes resulted in hypomyelination (i.e., reduced nu

217 Analysis of rats of both sexes revealed a dramatic reduction in brain size c

218 emotional states, and recordings in mice of both sexes revealed increased excitatory and reduced inh

219 Experiments with animals from both sexes revealed that disrupting cone LINC complexes

220 gs from pairs of T-stellate cells in mice of both sexes revealed that firing in the presynaptic cell

221 , and the similar global prevalence found in both sexes rules out any strong effect of Wolbachia on t

222 Human participants of both sexes searched arrays for targets of either a high-

223 entiates cocaine seeking via PrL-PFC CB1R in both sexes, sensitivity to cocaine priming injections is

224 Despite the presence of CY spigots in both sexes, sexual dimorphism with respect to CYs was st

225 Future lymphoma cases and controls for both sexes show different responses to the interaction o

226 Our data collected in both sexes show that, only in males, muscle speed signif

227 with the latter, results recorded in humans (both sexes) show a network-specific oscillatory profile

228 Whereas both sexes showed increases in pro-inflammatory factors,

229 Both sexes showed stronger early sensorimotor inhibition

230 sification in cultured rat cortical neurons (both sexes), silenced from plating.

231 ciated kinase are required for initiation in both sexes; similarly, Ca(2+)/calmodulin-activated kinas

232 igate the mechanisms of NMJ reinnervation in both sexes, specifically whether macrophage-derived vasc

233 We found that in both sexes, subjects with two or three offspring had sig

234 on the non-aversive object-in-place task in both sexes, suggesting that H2A.Z suppresses non-stressf

235 nnection is increased by social isolation in both sexes, suggesting that it may be a locus for isolat

236 ected by chance for males, females or across both sexes, suggesting that kinship may not influence vi

237 significantly more attractive to beetles of both sexes, than racemic fuscumol and a blend of host pl

238 Here we show in humans of both sexes that HC-SWRs are highly correlated with NC-GE

239 using two transgenic mouse lines (including both sexes) that express Cre-recombinase in MCs.

240 the developing rodent cerebellar cortex (of both sexes), there is a transient window when the domina

241 In both sexes, there was evidence supporting causal associa

242 Most aberrations were apparent in both sexes, though more pronounced in males, and exhibit

243 e- and paired-pulse TMS in healthy humans of both sexes to assess corticospinal excitability and GABA

244 vidence that venom is used differentially by both sexes to defend territories and mates.

245 al ability in animals by training ferrets of both sexes to detect a stream of repeating noise samples

246 togenetic techniques in anesthetized mice of both sexes to evaluate relationships between oral somato

247 sed an optogenetic approach in awake mice of both sexes to identify thalamostriatal and corticostriat

248 We trained mice of both sexes to perform visual detection tasks and used op

249 To test this hypothesis, we used mice of both sexes to quantify extracellular glutamate concentra

250 fit the fMRI response of human participants (both sexes) to a multi-category stimulus (e.g., a whole

251 ions, and bouton size analysis in the mouse (both sexes) to document that a circuit exists from layer

252 virus in an Rbp4-Cre transgenic mouse line (both sexes) to label these L5 efferents selectively.

253 that in cultured rat hippocampal neurons of both sexes, TRIM46 levels steadily increase at the AIS d

254 In both sexes, TRV130 prevented acute brain hypoxia induced

255 Both sexes undergo seasonal enhancement of hearing sensi

256 as inversely associated with hypertension in both sexes (user compared with nonuser; OR: 0.68; 95% CI

257 teractions in human visual cortex, including both sexes, using source-imaged steady-state visual evok

258 Participants (both sexes) viewed 2250 full-color scene images drawn fr

259 led that social and reproductive behavior of both sexes was significantly influenced by social and en

260 ns, and population data, infant vaccination (both sexes) was the optimal strategy in all models, but

261 Here, using 7T fMRI in humans (both sexes), we observed that prior knowledge acquired f

262 al connectivity analyses of human fMRI data (both sexes), we show that fast spindle density during ov

263 Finally, using behavioral tests (humans, both sexes), we show that it is knowledge of the speed-c

264 etic approach in SR conditional KO mice from both sexes, we demonstrate a cell-autonomous role for SR

265 ippocampal CA1 neurons from mice and rats of both sexes, we demonstrate that p38 MAPK is generally re

266 in the medial vestibular nucleus of mice of both sexes, we examined the relationship between gene ex

267 ch with intracranial recordings in humans of both sexes, we find evidence for both mechanisms.

268 Using a multifaceted approach in mice of both sexes, we found that neuropeptide Y (NPY) expressio

269 imary neuronal cultures of embryonic mice of both sexes, we here report that presynaptic overexpressi

270 Using 14 biological replicates spanning both sexes, we identified that ~30% of small ncRNAs are

271 In rhesus monkeys of both sexes, we investigated how these functionally disti

272 In ex vivo preparations from mice of both sexes, we measured MC and EGC tuning to natural che

273 e, by analyzing a battery of genetic mice of both sexes, we presented in vivo evidence supporting an

274 glial cultures from neonatal mouse cortex of both sexes, we show that SPARCL1 selectively increases e

275 sing responses to tones of ANFs from cats of both sexes, we show that, for a given ANF, the period hi

276 In this experiment with human subjects of both sexes, we tested for immediate stimulation impact o

277 Using primary rat cortical cells pooled from both sexes, we tested the hypotheses that the level of e

278 Both sexes were analyzed.SIGNIFICANCE STATEMENT Distinct

279 Human subjects of both sexes were asked to make a perceptual decision betw

280 Under cold-temperature stress, both sexes were less active and males exhibited less fre

281 recordings from brainstem slices of mice of both sexes were performed.

282 Both sexes were rich in protein and lipids.

283 Mice of both sexes were studied.

284 forebrain bundle (MFB) of a knock-in mouse (both sexes) were analyzed using confocal, super-resoluti

285 ns and observed that, although participants (both sexes) were generally sluggish, the typical conflic

286 ties are communities comprising all ages and both sexes where multiple social learning pathways invol

287 (CAP) neurons mediate aggressive approach in both sexes, whereas functionally downstream dimorphic bu

288 icient NOD mice developed accelerated T1D in both sexes, which was associated with increased accumula

289 erior colliculus (IC) of common marmosets of both sexes while they performed a tone-in-noise detectio

290 TA inhibits food-seeking and food intake (in both sexes), while optogenetic inhibition of this circui

291 e and tyrosine metabolites were increased in both sexes, while 1,5-anhydroglucitol levels decreased i

292 edictive of stress-induced susceptibility in both sexes, while prestress behavior is predictive only

293 ns of the afferent innervation in gerbils of both sexes with computational modeling of a single cell.

294 (GCs) and glomerular interneurons in mice of both sexes with four major findings.

295 mitochondrial membrane potential in mice of both sexes with genetically induced, severe mitochondria

296 ng of transgene-expressing PCs in zebrafish (both sexes) with variable copy numbers for tuning expres

297 neurons, derived from E16-18 mouse embryos (both sexes), with mito-GFP allowed monitoring of the tra

298 against distinct stress-induced behaviors in both sexes, with (2S,6S)-HNK attenuating learned fear in

299 ratios showed similar downward patterns for both sexes, with a faster decline for women than for men

300 ere was a decrease in body fat percentage in both sexes, with SCI females disproportionately affected