ライフサイエンスコーパス: bothersome

1 s; severity: 0 = Not bothersome to 10 = Very bothersome).

2 of >= 3 points (range: 0 to 6, 6 being most bothersome).

3 requency or the degree to which symptoms are bothersome.

4 in health care activities deemed helpful or bothersome.

5 lf-management) reported as either helpful or bothersome.

6 tense, perceived as less frequent, or not as bothersome.

7 h IOL groups reporting halo symptoms as very bothersome.

8 se; 55% reported that at least 1 AE was very bothersome.

9 ymptoms worsened over the day and were quite bothersome.

10 existing urinary symptoms were generally not bothersome.

11 medication that was helpful (130 [79.8%]) or bothersome (128 [78.5%]).

12 Ring-shaped dysphotopsia is negligibly bothersome 6 months after surgery.

13 ranging one's life (41.9%), and experiencing bothersome adverse effects (41.6%) were notable burdens.

14 More frequent bothersome adverse events of special interest included s

15 , psychiatric and autonomic problems, become bothersome and disabling in some patients.

16 symptomatic, or whose symptoms are minimally bothersome and pose no apparent risk to driving safety,

17 Pain is among the most frequently reported, bothersome, and disabling symptoms described by patients

18 site clinicians considered the protocol very bothersome, and only 2% felt it should be discontinued.

19 erally not noticed by participants or deemed bothersome, and resolved without intervention.

20 Postmenopausal women (N = 206) with bothersome anterior and apical vaginal prolapse interest

21 ing the same subscales (frequency, severity, bothersome) as the validated, Rasch-tested, linear-scale

22 Absence of the most bothersome associated symptom at 2 hours was reported by

23 ms (e.g., walking, bradykinesia) as the most bothersome at all durations while family more strongly p

24 al support quantification system, absence of bothersome bulge symptoms, and absence of prolapse retre

25 the patient to understand and tolerate these bothersome but nonharmful symptoms.

26 in or recommend it to somebody else, and how bothersome compensatory hyperhidrosis was.

27 conservative management emphasizing the most bothersome component.

28 , a standard criterion for treatment of this bothersome condition has not been identified.

29 s urinary incontinence (SUI) is a common and bothersome condition.

30 pears to be the predominant mechanism of the bothersome cough of acute bronchitis.4.

31 sover trial of patients with lung cancer and bothersome cough.

32 f symptoms rated as quite a bit or extremely bothersome declined from before to after surgery except

33 sability had more numerous, longer, and more bothersome disabilities than people with heart disease d

34 e variable was the change in on time without bothersome dyskinesia (ie, good quality on time) at 3 mo

35 al stool consistency and faecal incontinence bothersome enough to seek treatment, we were unable to f

36 Eligible individuals needed to report new, bothersome fatigue or cognitive dysfunction persisting f

37 ose levels was doable for 18 (37.5%) and too bothersome for 9 (18.8%).

38 Arm symptoms were significantly more bothersome for SNAD compared with SNR patients at 6 mont

39 isceral pain is among the most prevalent and bothersome forms of chronic pain, but their transmission

40 visits and reported one or two of their most bothersome function and symptom issues from categories b

41 ved the skin patch after nine hours due to a bothersome garlic odour.

42 Clinically meaningful or bothersome gastrointestinal effects are not associated w

43 incident bacterial vaginosis (iBV) may cause bothersome genital symptoms and increase human immunodef

44 these goals, and as many as 3 helpful and 3 bothersome health care activities.

45 When asked what they would do if they had bothersome heartburn and could have either drug for free

46 Postmenopausal women with at least 14 bothersome hot flashes per week recorded hot flashes for

47 Women with bothersome hot flashes were entered onto this trial, wer

48 The leading most bothersome impact reported by adults was anxiety associa

49 Among adolescents, the leading most bothersome impact was on school (n = 7/13 asked, 53.8%),

50 Side-effects were minimally bothersome in both groups within the first year of treat

51 Motion sickness remains bothersome in conventional transport and is an emerging

52 A diagnosis may reveal merely a bothersome issue or potentially a sight-threatening or l

53 For patients reporting one bothersome issue, absolute scores identified it correctl

54 For patients reporting two bothersome issues, absolute scores identified at least o

55 d which way better identified patients' most bothersome issues: worst scores in absolute terms or wor

56 Despite these bothersome lower urinary tract problems in men, conserva

57 alence trial, men in seven UK hospitals with bothersome lower urinary tract symptoms or urinary reten

58 1077 men (>=18 years) with bothersome LUTS recruited between June 2018 and August 2

59 The most effective treatment for bothersome menopausal symptoms is evidence-based, menopa

60 ontraindications to hormone therapy who have bothersome menopausal symptoms.

61 T for the treatment of menopausal women with bothersome menopausal symptoms.

62 d absence of the participant-designated most bothersome migraine-associated symptom (among photophobi

63 -mg and 25-mg doses, and absence of the most bothersome migraine-associated symptom at 2 hours only w

64 ter the initial dose and absence of the most bothersome migraine-associated symptom at 2 hours.

65 Resolution of most bothersome migraine-associated symptom was 14.1% higher

66 Migraine pain levels and most bothersome migraine-associated symptoms (MBS) were recor

67 nts were pain relief at 2 h, absence of most bothersome migraine-associated symptoms (MBSs) at 2 h, a

68 not troublesome, and only 1 patient found it bothersome more than 2 years after surgery.

69 uestionnaire was divided into two subscales: Bothersome Ocular Symptoms (six questions), and Impact o

70 Nocturia is one of the most common and bothersome of lower urinary tract symptoms.

71 were described as being more than "somewhat bothersome." Overall symptom burden and severity each we

72 Pain was determined by self-reports of bothersome pain in the last month.

73 Approximately 53% experienced bothersome pain, 11% had difficulty initiating sleep, 6%

74 s 3 or more medically unexplained, currently bothersome physical symptoms plus a long (> or = 2 years

75 cal activity criteria with at least stage II bothersome POP were eligible.

76 ations, which may impose patient discomfort, bothersome positioning, and suboptimal sensitivity in ce

77 ted whether PROs can identify patients' most bothersome quality-of-life issues and compared approache

78 Absolute scores identify patients' most bothersome quality-of-life issues better than change sco

79 bilitation are beneficial in adults who have bothersome respiratory symptoms, especially dyspnea, and

80 Digital photographs were captured where bothersome, salve-related events were reported.

81 d with controls, each therapy group reported bothersome sexual dysfunction; radical prostatectomy was

82 of both men and women reported at least one bothersome sexual problem.

83 ity, lessens fat accumulation, and has fewer bothersome side effects than treatment with a gonadotrop

84 nd negative affect, or how much the pain is "bothersome", significantly impacts the sufferers' qualit

85 g a visible sign associated with other, more bothersome skin complaints.

86 -13.1; p<0.0001) and freedom from their most bothersome symptom (247 [40%] vs 201 [31%], risk differe

87 .4-13.0; p<0.0001) and freedom from the most bothersome symptom (336 [50%] of 666 participants vs 241

88 e 10, 95% CI 6-14) and freedom from the most bothersome symptom (35% vs 27%, p=0.0009; risk differenc

89 Changes in severity of participants' most bothersome symptom (MBS), vaginal maturation index (VMI)

90 ratio, 1.54 [P < .001]) and absence of most bothersome symptom (median, 2 hours vs 3 hours; hazard r

91 freedom from pain and freedom from the most bothersome symptom (nausea, phonophobia, or photophobia)

92 che pain freedom and time to absence of most bothersome symptom (nausea, photophobia, or phonophobia)

93 freedom from pain and freedom from the most bothersome symptom (other than pain) identified by the p

94 ge of patients who were free from their most bothersome symptom 2 hours after the dose was 37.6% in t

95 versus placebo 21.3%) and freedom from most bothersome symptom at 2 h (lasmiditan 200 mg: 48.7%, odd

96 freedom from pain and freedom from the most bothersome symptom at 2 h after the treatment dose, were

97 freedom from pain and freedom from the most bothersome symptom at 2 h postdose.

98 re headache pain freedom and absence of most bothersome symptom at 2 hours after start of infusion.

99 ad freedom from pain and absence of the most bothersome symptom at 2 hours after the dose.

100 f participants who had freedom from the most bothersome symptom at 2 hours was 27.8% in the placebo g

101 re headache pain freedom and absence of most bothersome symptom at 4 hours and use of rescue medicati

102 I, 1.39-3.72]; P < .001) and absence of most bothersome symptom by 55.5% and 35.8% (between-group dif

103 sation of bloating, often ranked as the most bothersome symptom by patients with irritable bowel synd

104 o were free of pain and free from their most bothersome symptom than placebo.

105 n = 109), the vaginal atrophy score for most bothersome symptom was significantly better at 12 months

106 older patients experience constipation as a bothersome symptom with a negative impact on quality of

107 animals enable us to better understand this bothersome symptom, and have important clinical implicat

108 ion of patients' headache pain-free and most bothersome symptom-free at 2 h post-dose for each dose o

109 subtests were agreed to assess important or bothersome symptoms (p < .05).

110 Overall, the low level of bothersome symptoms and continued recovery through the f

111 ients with AR and CRS continue to experience bothersome symptoms despite adequate treatment.

112 ric patients with cancer experience severely bothersome symptoms during treatment.

113 the control group were more likely to report bothersome symptoms of stress incontinence than those in

114 For those with bothersome symptoms self-management may be an effective

115 d, patients with symptomatic anemia or other bothersome symptoms should be treated.

116 Bothersome symptoms were common.

117 The most bothersome symptoms were reduced after surgery: preopera

118 Specific bothersome symptoms were reported by less than 24% of pa

119 egiver needs, particularly the high rates of bothersome symptoms, risk of functional and cognitive de

120 Patients ranked urgency and pain as the most bothersome symptoms, while physicians and nurses ranked

121 use were reported by caregivers as the most bothersome symptoms.

122 d email alerts were distributed for severely bothersome symptoms.

123 ange from 0 to 64, ranked from least to most bothersome symptoms.

124 occurred; and (3) quantification of specific bothersome symptoms.

125 Two bothersome tics on the Hopkins Motor/Vocal Tic Scale (HM

126 ssment to evaluate change in the severity of bothersome tics.

127 two sex-separated cohorts reporting chronic, bothersome tinnitus (control males n = 7,315, tinnitus m

128 N = 15) against an SSD cohort with no or non-bothersome tinnitus (NO TIN; N = 15) using resting-state

129 We contrasted an SSD cohort with bothersome tinnitus (TIN; N = 15) against an SSD cohort

130 Eligibility criteria included bothersome tinnitus (Tinnitus Functional Index [TFI] sco

131 Bothersome tinnitus in single-sided deafness (SSD) is pa

132 clinical study including adults with chronic bothersome tinnitus recruited from Washington University

133 3%] females and 41 [47%] males) with chronic bothersome tinnitus, of whom 53 (60%) had at least 13-po

134 evaluating and managing care for adults with bothersome tinnitus.

135 evaluating and managing care for adults with bothersome tinnitus.

136 = Every time I eat/always; severity: 0 = Not bothersome to 10 = Very bothersome).

137 set of participants with at least moderately bothersome vaginal atrophy symptoms at baseline (n = 109

138 beyond the hymen (anatomic success), (2) no bothersome vaginal bulge symptoms, and (3) no re-treatme

139 usal hormone therapy is appropriate to treat bothersome vasomotor symptoms among women in early menop

140 with estrogen is the first-line therapy for bothersome vasomotor symptoms and GSM symptoms, but nonh

141 Efficacious treatments for women with bothersome vasomotor symptoms or GSM symptoms include ho

142 mes included frequency of "severe" and "most bothersome" visual disturbances.

143 nts previously treated with Nd:YAG laser for bothersome vitreous floaters showed less dense vitreous,

144 Most often mentioned as bothersome were statins (25 of 97 users [25.8%]) and ant

145 which some were reported as being severe or bothersome, who had not had a menstrual period for at le

146 ents were generally manageable and minimally bothersome within the first year of treatment.