ライフサイエンスコーパス: bp.

1 tions (an average of one insertion every 6.0 bp).

2 The delivery of large DNA vectors (>100 000 bp) remains a limiting step in the engineering of mammal

3 with both short (<600 bp) and long (>35 000 bp) insert sizes producing high-quality scaffolds.

4 ppeared from the fossil record around 40,000 bp, after a demographic history of small and isolated gr

5 ite of El Sidron, Spain, dated around 49,000 bp, constituted a closely related kin group, making thes

6 requency-division multiplexed (0.5 m x 1,000 bps) prototype are demonstrated as proof-of-principle ex

7 sy, 15,027 bp) and Florida (mt-FLpsy, 15,012 bp), USA, were acquired.

8 sequences from California (mt-CApsy, 15,027 bp) and Florida (mt-FLpsy, 15,012 bp), USA, were acquire

9 s) had genome lengths of 178,262 bp, 171,045 bp, and 171,454 bp, respectively, and were phylogenetica

10 rdB copies were in long form (nrdB(L), 1,059 bp) and two were in short form (nrdB(S), 378 bp).

11 These three SNPs covered a region of 43,067 bp; we referred to this region as the MD/FDP locus.

12 amples, with 94% of deletions larger than 10 bp, and essentially no insertions at all tested target s

13 fragment containing the five motifs (the 10-bp, 10-bp-like, 10-bp-related, Region 2 and Fifth motifs

14 islands are quite short ( approximately 100 bp), are enriched near active genes, and often occur at

15 interactions at a high resolution (e.g. 100 bp), we developed a computational method that integrates

16 rage depth using longer reads (e.g., >/= 100 bp).

17 lization: large deletions (median size, ~100 bp) with little or no homology at deletion junctions.

18 eed to be either long reads (longer than 100 bp) or joined paired-end reads.

19 mplify fragments (horse; 85 bp, soybean; 100 bp, sheep; 119 bp, poultry; 183 bp, pork; 212 bp and cow

20 However, for DNA fragments shorter than 100 bp, all sets of parameters performed poorly yielding res

21 ied out with short (36-50 bps), long (75-100 bps), single-end, or paired-end reads, the impact of the

22 nt distances ( approximately 20, 50, and 100 bps), we analyzed the repair outcomes by deep sequencing

23 a of Cytochrome b (380 bps) and D-loop (1000 bps).

24 to assays with larger amplicon sizes (>/=105 bp) (P < .001).

25 s (horse; 85 bp, soybean; 100 bp, sheep; 119 bp, poultry; 183 bp, pork; 212 bp and cow; 271 bp) of th

26 ngth, and 10 dsRNA segments ranged from 1192 bp (S4) to 3958 bp (L1), encoding 12 viral proteins.

27 o different DNA regions in beef (106 and 120-bp) and buffalo (90 and 138-bp) mitochondrial genes to d

28 e associated imaging contrast for up to 1200 bp, enabling us to quantify dsDNA length with up to 2 bp

29 tal monitoring) and long amplicons (800-1200 bps, designed to cover the entire resistance genes).

30 The two amplicons generated span 7,124 bp, providing substantial sequence length and numbers of

31 A single-channel (2 m x 125 bps) prototype and an 8-channel frequency-division multi

32 he maximum Range and Bit Rate of 2 m and 125 bps, respectively, demonstrated recently.

33 enced RNA-sequencing samples using long (126-bp) paired-end reads.

34 cky ends over three helical periods (100-130 bp) using single-molecule fluorescence resonance energy

35 PB-79 (GenBank accession no. KU901725; 1313 bp), Streptomyces sp. Kz-28 (GenBank accession no. KY000

36 8 bp) and one large single copy (LSC; 89,132 bp).

37 CENP-A protects DNA lengths centered on 133 bp, consistent with octameric nucleosomes with DNA unwra

38 Kz-24 (GenBank accession no. KY000533; 1367 bp) showed only 96.2% sequence similarity to S. malaysie

39 Kz-32 (GenBank accession no. KY000536; 1377 bp) and Streptomyces sp. Kz-67 (GenBank accession no. KY

40 Kz-28 (GenBank accession no. KY000534; 1378 bp), Streptomyces sp. Kz-32 (GenBank accession no. KY000

41 eef (106 and 120-bp) and buffalo (90 and 138-bp) mitochondrial genes to discriminate beef and buffalo

42 Kz-67 (GenBank accession no. KY000540; 1383 bp) showed ~89.5% similarity to the nearest type strain

43 the diffusion of various lengths (99 to 1385 bp) of single DNA molecules at rates up to 10 um(2)/s.

44 ses revealed a VB12-riboswitch, cbiMCbl (140 bp), within the 5' UTR that controls the expression of d

45 bp) and subnucleosome-sized (such as 101-140 bp) peaks of digested chromatin fragments with MPE-seq b

46 lysis of the assembled draft genome (1462509 bp) revealed the presence of 29 putative reductive dehal

47 engths (of 4-5 bp) and stem lengths (of 7-15 bp).

48 tively large minimum sequence lengths (>/=15 bp) compared with the average length of known transcript

49 nome sequencing using short-read (e.g., <150 bp), next-generation sequencing technologies has reinvig

50 tradictory reports as to whether wider ( 150 bp) NDRs instead contain unstable, micrococcal nuclease-

51 When homology at the matched end is </=150 bp, efficient repair depends on the recombination enhanc

52 When homology at the second end is </=150 bp, second-end capture becomes inefficient and repair sh

53 Here we used short (150-bp) and long (multi-kb) synthetic reads to evaluate stra

54 ion afforded by sequencing the entire (~1500 bp) gene.

55 Mammalian antibody switch regions (~1500 bp) are composed of a series of closely neighboring G4-c

56 op closure involving closely spaced (131-151 bp) loxP sites to investigate the in-aqueo ensemble of c

57 imately ten petabases of DNA sequence (10 16 bp).

58 ut CDEII in the former is twice as long (160 bp) as CDEII in the latter (80 bp).

59 atosome, containing H1 and approximately 160 bp, and then converts it to a core particle, containing

60 p), medium (M) (3244 bp) and small (S) (1608 bp) negative sense, single-stranded RNA segments.

61 intermediate particles containing 154 or 161 bp, corresponding to 7 bp protruding from one or both si

62 A derived from human chromosomes (103 vs 172 bp, p < 0.0001), corresponding to the 3(rd) percentile o

63 onths (16 of 21 patients; mean increase, 175 bp [95% CI, 79 to 271]) and 12 months (16 of 18 patients

64 ence of croaker elovl4, which contained 1794 bp (excluding the polyA tail), including 909 bp of codin

65 eristically located at a fixed distance (~18 bp) downstream of the RSS.

66 ted p53 REs contain spacers between 1 and 18 bp; however, their functional significance is unclear at

67 (fragments with a length between 140 and 180 bp) DNA fragments are recovered and sequenced on Illumin

68 soybean; 100 bp, sheep; 119 bp, poultry; 183 bp, pork; 212 bp and cow; 271 bp) of the mitochondrial c

69 bp (nucleosome repeat length (NRL) = 160-184 bp).

70 requently observed nucleosome-sized (141-190 bp) and subnucleosome-sized (such as 101-140 bp) peaks o

71 dicted genes) and P. micropora NZ27 (977,190 bp, GC-content = 39.9%, 911 predicted genes) and compare

72 ngth library (565 bp) and mini-barcodes (193 bp) contain enough taxonomic resolution to differentiate

73 the mammal-specific Area II (-2139 to -1958 bp) affects minor or major aspects of organogenesis.

74 and that only fibres with longer NRLs (>=197 bp) can more likely adopt the 1-start organisation.

75 and PRS2 hotspots encompassing 1026 and 1976 bp, respectively.

76 ir has a unique 93 base pair (bp)-long (+/-2 bp) ArgR-binding sequence containing two ARG boxes (39 b

77 We examined the activity of a 2-bp, rNMP-dependent deletion hotspot [the (TG)2 hotspot]

78 ndicate a mutation rate of 2.94 indels (1-20 bp) and 0.16 SVs (>20 bp) per generation.

79 e of 2.94 indels (1-20 bp) and 0.16 SVs (>20 bp) per generation.

80 npaired guanosines flanking short (12- to 20-bp) dsDNA (Y-form DNA) were highly stimulatory and speci

81 tion events involving relatively short (<200 bp) homologous sequences, where RecA-mediated recombinat

82 e markers (i.e. amplicons with less than 200 bp) suitable for DNA metabarcoding by evaluating the tax

83 ith both short amplicons ( approximately 200 bps, representative of ARG amplicon lengths commonly use

84 ites in long introns (especially those >2000 bp) have significantly lower pi (nucleotide diversity) a

85 MuGENT require large arms of homology (>2000 bp) surrounding each genome edit, which necessitates lab

86 e mitogenomes were 15,188, 15,235 and 15,207 bp, respectively.

87 mutation in CAPN3 could be identified; a 21-bp, in-frame deletion (c.643_663del21).

88 Our data identified a short (22 bp) DNA element containing a key repressive element.

89 of short scaffolds (N50 = approximately 2200 bp).

90 rom Illumina reads alone impossible (N50=222 bp).

91 (+76 bp) and decreased in the controls (-23 bp) (p=0.050).

92 plified specific DNA fragments from dog (230 bp), duck (283 bp), buffalo (363 bp), goat (396 bp), and

93 Species-specific SNP position (230 bp) in the matK region that is characteristic of D. hami

94 ic amplification of yfiR (375 bp), hlyA (234 bp) and eaeA (151bp), being one of the primers for each

95 CDEI (8 bp) and CDEIII (~25 bp) are conserved between Kluyveromyces lactis and Sacch

96 son to that for a distal ( approximately 250 bp) location of the same sequence.

97 paired-end tags is increased (up to 2 x 250 bp).

98 largest bacteriophage genes to date (14,256 bp).

99 ruses (YSLPVs) had genome lengths of 178,262 bp, 171,045 bp, and 171,454 bp, respectively, and were p

100 , poultry; 183 bp, pork; 212 bp and cow; 271 bp) of the mitochondrial cyt b, lectin, 12S rRNA, 12S rR

101 c DNA fragments from dog (230 bp), duck (283 bp), buffalo (363 bp), goat (396 bp), and sheep (477 bp)

102 The PCR products (294 bp) was subsequently digested with HinfI (New England Bi

103 that nucleotides in the close vicinity (+/-3 bp) of methylated cytosines mutate less frequently.

104 isting of Alexa Fluor 350 as the donor, a 30 bp (9.7 nm) DNA templated K21 aggregate as the bridge, a

105 the nuclease domains are too far apart (>30 bp) to dimerise and produce a double-strand DNA break us

106 With read lengths of currently up to 2 x 300 bp, high throughput and low sequencing costs Illumina's

107 ntifies binding specificity over a large (31-bp) binding site by iteratively fitting a feature-based

108 arcode primer pairs targeting short (127-314 bp) fragments of the cytochrome c oxidase I (CO1) DNA ba

109 The entire MYOC gene (17,321 bp) was captured including the promoter, introns, UTRs a

110 luding large (L) (6766 bp), medium (M) (3244 bp) and small (S) (1608 bp) negative sense, single-stran

111 A proximal promoter sequence (-8 to +33 bp) of Frmpd1 binds to neural retina leucine zipper (NRL

112 ime-stamped second hypervariable region (330 bp) of G-gene sequence data (global, n = 483; and Ontari

113 e length in CD8(+) T cells (2225 versus 3397 bp; P<0.001).

114 ify two abundant satellite DNAs, alpha (~340 bp) and CapA (~1,500 bp), from short-read clustering of

115 tric GUS assays showed that the shorter (345 bp) and medium (827 bp) fragments of nsLTP promoter func

116 mitochondrial genome is comprised of 16,345 bp, and contains the expected 37 genes and control regio

117 cline in telomere length over the year of 35 bp (P<0.05).

118 sequence from P. longichromatophora (979,356 bp, GC-content = 38.8%, 915 predicted genes) and P. micr

119 cing technologies produced reads of 25 or 36 bp, and only from a single-end of the library sequence.

120 onths (16 of 18 patients; mean increase, 360 bp [95% CI, 209 to 512]).

121 om dog (230 bp), duck (283 bp), buffalo (363 bp), goat (396 bp), and sheep (477 bp).

122 some fibers with short DNA linkers L = 13-37 bp (nucleosome repeat length (NRL) = 160-184 bp).

123 for the specific amplification of yfiR (375 bp), hlyA (234 bp) and eaeA (151bp), being one of the pr

124 bp) and two were in short form (nrdB(S), 378 bp).

125 ochondrial genomic data of Cytochrome b (380 bps) and D-loop (1000 bps).

126 tion of Frmpd1 promoter region, -505 to +382 bp, activated reporter gene expression in mouse retina i

127 s compared with baseline (mean increase, 386 bp [95% CI, 178 to 593]); in exploratory analyses, simil

128 assay for amplification of the P20 gene (387-bp) characteristic of CTV was first designed/optimized a

129 inding sequence containing two ARG boxes (39 bp) and residual sequences.

130 NA segments ranged from 1192 bp (S4) to 3958 bp (L1), encoding 12 viral proteins.

131 , duck (283 bp), buffalo (363 bp), goat (396 bp), and sheep (477 bp).

132 ed with rapid, large-scale ( approximately 4 bp) variations in DNA length.

133 f cognitive control was approximately 3 to 4 bps, demonstrating that cognitive control as a higher-le

134 Nucleotide sequence analysis revealed a 4-bp (AGTC) insertion in the oprD gene, resulting in a fra

135 , in part, to the small DNA fragments (</=40 bp) directly produced by high LET radiation, the size of

136 eferentially to DNA molecules longer than 40 bp, and two CAF1-H3-H4 complexes concertedly associate w

137 othesis, BoHV-1 DNA fragments (less than 400 bp) containing potential GR and KLF binding sites were i

138 ntergenic viral DNA fragments (less than 400 bp) containing two GREs and putative KLF binding sites p

139 mber of bases in the genome (~6200 vs. ~4000 bp), implying that they may have similar functional cons

140 s A23 has a linear compact genome of 395,405 bp, with a 33.62% G+C content.

141 The completed 629,409-bp 'Mnola' genome (Candidatus Mycoplasma girerdii str.

142 rrays with linker DNA length of 36 bp and 41 bp (3.5 turns and 4 turns of DNA double helix, respectiv

143 We deleted 430 bp, encompassing one of the ERalpha-binding sites, there

144 amilies and a large genomic deletion (36,445 bp) encompassing exons 2-7 of TRPM1 present in 13 Ashken

145 In addition to that, we identified about 450 bp (upstream of their transcription start site) of the a

146 For a cDNA of ~450 bp, about half of the expressed proteins were multimeric

147 ngths of 178,262 bp, 171,045 bp, and 171,454 bp, respectively, and were phylogenetically closely rela

148 vel enhancer, located between +4517 and 4662 bp, but the luciferase reporter assay demonstrated that

149 falo (363 bp), goat (396 bp), and sheep (477 bp).

150 inii var. chinensis (complete genome 122,492 bp), and L. occidentalis (partial genome of 119,680 bp),

151 ostmortem brain and blood found (i) the 4977 bp 'common deletion' was neither the most frequent delet

152 lysis and identified large indels (50 to 499 bp) and CNVs (500 bp and larger) in these accessions.

153 Polymorphic small repeats (1-5 bp) had also higher expression divergence compared with

154 ured with short TRs (repeat unit length, 1-5 bp).

155 riod close to the helical turn of DNA (~10.5 bp).

156 ion of hairpins such as loop lengths (of 4-5 bp) and stem lengths (of 7-15 bp).

157 ation events at both short ( approximately 5 bp) and long ( approximately 1 kb) genomic distances, sh

158 to the TSS, with 38 preferences tight (+/-5 bp).

159 ercoiling in fibers with L = 10n and 10n + 5 bp, different flexibility of the two types of fibers, an

160 DNA packaging step-size of approximately 2.5 bp, such that the step-size is probably determined by th

161 Vs), 95.98% for insertions and deletions <50 bp (indels) and 95.99% for structural variants.

162 novel large insertions, small indels (10-50 bp), and short tandem repeat expansions and contractions

163 variants (SNVs) plus 0.7 million small (1-50 bp) insertions and deletions (indels) that are consisten

164 30,275 larger TRs (repeat unit length, 2-50 bp).

165 indel variants (<50 bp) and 27,622 SVs (>=50 bp) per genome.

166 We identify 818,054 indel variants (<50 bp) and 27,622 SVs (>=50 bp) per genome.

167 explore melting properties for short (</=50 bp) double-stranded DNA homopolymers.

168 Once single-end reads are at a length of 50 bp, the results do not change substantially for any leve

169 f the MHC and 22368 variants smaller than 50 bp, 49% more variants than a mapping-based benchmark.

170 eriments to be carried out with short (36-50 bps), long (75-100 bps), single-end, or paired-end reads

171 Cost-saving short (50-bp) single-end reads and Nextera (R) library preparation

172 eccDNAs (<500 bp) than the larger ones (>500 bp) (p < 0.01).

173 llite DNAs, alpha (~340 bp) and CapA (~1,500 bp), from short-read clustering of sequencing datasets f

174 ng mitochondrial DNA (mtDNA) haplotypes (500 bp), microsatellite genotypes (17 loci) and sex from 128

175 in human cells at the 1-3 nucleosome (50-500 bp) scale, obtained using ionizing radiation-induced spa

176 y higher GC content in smaller eccDNAs (<500 bp) than the larger ones (>500 bp) (p < 0.01).

177 ccumulation over the first approximately 500 bp, suggesting that Spt5 is required for transcription p

178 genomic DNA (gDNA) fragments of length >500 bp, and it can successfully discriminate single mismatch

179 n (2.7), and low linkage disequilibrium (500-bp) were observed in Chikhwawa District, Malawi, an area

180 B virus (WSHBV) has a circular genome (3,542 bp) with the prototypical codon organization of hepadnav

181 the transcription start site (distance: 542 bp) than to the start codon (distance: 704 bp), which co

182 the assembled chloroplast genome was 122,561 bp, which is similar to 122,474 bp in the closely relate

183 onstrated that both full-length library (565 bp) and mini-barcodes (193 bp) contain enough taxonomic

184 e chromosome's relatively small size (16,569 bp) necessitates the ability to detect extremely focal e

185 ontaining variant T alleles at -1018 and -57 bp) exhibited the highest promoter activity.

186 Based on a new six-gene data set (5707 bp) for 92 taxa including Oxyporinae (outgroup), represe

187 nly identify the germline microhomology (1-6 bp) anticipated to prime such slippage in one-third of F

188 aling of short regions of microhomology (2-6 bp) across the break-site.

189 repetitive, short DNA motifs (usually 1 to 6 bp) abundant in eukaryotic genomes.

190 sional diffusion constant, 26+/-1.8 x 10(6) (bp)(2) s(-1).

191 s highly enriched in short-size cfDNA (30~60 bp).

192 s able to handle reads with both short (<600 bp) and long (>35 000 bp) insert sizes producing high-qu

193 ion involves step-like events of 200 nm (600 bp) size and is strongly suppressed by forces above 1 pN

194 HNARs are spanning over 600 bp, featuring high in vivo and predicted in vitro nucleo

195 nnealing linked with NHEJ, inserting 4 to 61 bp, mostly originating from the surrounding of breakpoin

196 sive array of long repeat sequences (65-6499 bp) that are associated with CNV, LOH, and chromosomal i

197 n that it requires a minimal sequence of >65 bp; however, other than a GAGA motif, the three Fab-7 LB

198 ome is tripartite, including large (L) (6766 bp), medium (M) (3244 bp) and small (S) (1608 bp) negati

199 anti-silencing properties for the small (679 bp) CBX3-UCO element and we now confirmed this observati

200 d L. occidentalis (partial genome of 119,680 bp), we identified 110 genes, 34 of which represented tR

201 t to generate high-quality large-insert (680 bp) paired-end libraries using a range of 50 pg to 50 ng

202 urth (YSLGV), with a genome length of 73,689 bp, was related to group III in the extended family Mimi

203 on, and had a mean fragment size of only 699 bp--close to single-enhancer resolution.

204 Targeted genomic deletion (<7 bp) of the MITF motif within the MET enhancer suppressed

205 s containing a rat proglucagon promoter (700 bp) driving enhanced green fluorescent protein (AAV GCG-

206 2 bp) than to the start codon (distance: 704 bp), which corresponds to open chromatin, especially in

207 A conjugative plasmid of 55,706 bp (pBRZ01) carrying the vanA cluster was identified and

208 The size of the genome is 158,712 bp, smaller than 160,100 bp of the C. papaya chloroplast

209 etic enhanced green fluorescent protein (720 bp) clones from 0.93% to 83.22%, corresponding to a decr

210 ecognition of a non-Watson-Crick G(-1):A(73) bp, which had not been described previously.

211 cies, Diabrotica virgifera virgifera (16,747 bp) and Diabrotica barberi (16,632; Insecta: Coleoptera:

212 arated by one small single copy (SSC; 18,758 bp) and one large single copy (LSC; 89,132 bp).

213 2, TL increased in the intervention arm (+76 bp) and decreased in the controls (-23 bp) (p=0.050).

214 CDEI (8 bp) and CDEIII (~25 bp) are conserved between Kluyveromy

215 as long (160 bp) as CDEII in the latter (80 bp).

216 osome-sized (fragments with a length of <=80 bp) and mononucleosome-sized (fragments with a length be

217 one pair of inverted repeats (IRs) of 26,819 bp, which were separated by one small single copy (SSC;

218 ed that the shorter (345 bp) and medium (827 bp) fragments of nsLTP promoter function as grain-specif

219 onstructed HBV haplotypes in a region of 836 bp, which contains the major immune epitopes and drug re

220 ic primers that amplify fragments (horse; 85 bp, soybean; 100 bp, sheep; 119 bp, poultry; 183 bp, por

221 yielded closed genome sequences of 1,914,862 bp, identical in length and sequence identity.

222 erence unique insertions spanning 18,048,877 bp, some of which disrupt exons and known regulatory ele

223 s produced 16,115 contigs with an N50 of 889 bp, over 90% of which has significant sequence similarit

224 sly reported enhancer region (-9435 to -8922 bp).

225 esponds to the break site for a large (3,895 bp) deletion observed in mitochondrial disease patients.

226 Here, we show that small (5-9 bp) inverted repeats drive the formation of large palind

227 order of magnitude when positioned close (9 bp) to the promoter, in comparison to that for a distal

228 edian deletion size using single sgRNAs is 9 bp, we also obtain large deletions of up to 600 bp.

229 ressor (Bcor) gene, most commonly within a 9-bp "hotspot" in Bcor exon 8.

230 The resulting high-resolution (9-bp) map shows uniform absolute occupancies.

231 recognition sites are separated by up to 90 bp, Fis represses IHF binding and weak DnaA interactions

232 he model yields a speed of DNA uptake of 900 bps(-1) and a reversal force of 17 pN.

233 At 80,923 bp, I. nocturnus now holds the record for the largest an

234 utions per site within the concatenated (945 bp) nucleotide dataset, implying that probabilistic phyl

235 SuRCA), with an N50 scaffold size of 464 955 bp (based on a genome size of 606 Mbp), 221 640 contigs

236 hs of TmELO1 and TmELO2 were 1005 bp and 972 bp, respectively and the corresponding peptide sequences

237 ously explained by an initial >457 basepair (bp) HSV-1 x HSV-2 crossover followed by back-recombinati

238 mutant of the KNOX1 mutant brevipedicellus (bp) that we termed flasher (fsh), which promotes stem an

239 ding stronger preferences for A*T versus G*C bps, TA versus GG steps, and also suggests enrichment at

240 th an array of Shockley partial dislocations bp:-bp on every basal plane and the 30 degrees twist GB

241 als that in both cases, m1A forms a m1A*T HG bp, which is accompanied by local and global structural

242 ere, we use structural features unique to HG bps (syn purine base, HG hydrogen bonds and constricted

243 To gain insights into transient HG bps, we used solution-state nuclear magnetic resonance s

244 anscription, which are found within areas I (bp -2694 to -2561), II (bp -2139 to -1958), III (bp -187

245 ound within areas I (bp -2694 to -2561), II (bp -2139 to -1958), III (bp -1879 to -1799), and IV (bp

246 2694 to -2561), II (bp -2139 to -1958), III (bp -1879 to -1799), and IV (bp -6200 to -5670).

247 Mean TL (in bp) was associated with exclusive breastfeeding at 4-6 w

248 es revealed that cytokinin levels are low in bp, but fsh restores cytokinin levels to near normal by

249 h suppressor are significantly lower than in bp, which is likely due to elevated expression of JA ina

250 to -1958), III (bp -1879 to -1799), and IV (bp -6200 to -5670).

251 lilee, Israel) and dated to 54.7 +/- 5.5 kyr bp (arithmetic mean +/- 2 standard deviations) by uraniu

252 During the Last Glacial Maximum (25-15 kyr bp), diversity declined markedly, although forbs remaine

253 d radiocarbon years before present (cal. kyr bp), glacial retreat opened an approximately 1,500-km-lo

254 ence of moose and elk at about 11.5 cal. kyr bp, and boreal forest approximately 10 cal. kyr bp.

255 glaciated North America before 12.6 cal. kyr bp, are unlikely to have travelled by this route into th

256 n and mammoth by approximately 12.6 cal. kyr bp, followed by open forest, with evidence of moose and

257 the stabilization of low-boiling point (low-bp) perfluorocarbons (PFCs) at physiological temperature

258 cles can lead to artefacts (10(-6) mutations/bp).

259 Both sets of genes share an 11-base pair (bp) activator motif.

260 erse mutations encompassing a 643-base pair (bp) deletion (100% efficiency), a stop codon insertion (

261 d dystrophy (adCORD) caused by 12 base pair (bp) deletion at proline 351 of hAIPL1 (P351Delta12) muta

262 rmed that cats homozygous for a 2 base pair (bp) deletion within IQ calmodulin-binding motif-containi

263 We oxidized a 32 base pair (bp) double-stranded (ds) oligonucleotide representing ex

264 associated with approximately 80 base pair (bp) of DNA, which is located at a position that correspo

265 ribe a novel mutation within a 15 base pair (bp) region of the PDE3A gene and define this segment as

266 APN2 also suppresses 2-base pair (bp) slippage mutagenesis in RNH201-deficient cells.

267 t folate-associated DMR was a 400-base pair (bp) spanning region annotated to the LGALS3BP gene.

268 e, recognizes a palindromic eight base pair (bp) symmetric sequence, 5-ATTTAAAT-3, and cleaves that t

269 Each peak-pair has a unique 93 base pair (bp)-long (+/-2 bp) ArgR-binding sequence containing two

270 We found a rare noncoding 12-base-pair (bp) deletion (del12) in intron 4 of ASGR1, which encodes

271 xon 18 of BRCA1, we replace a six-base-pair (bp) genomic region with all possible hexamers, or the fu

272 ptical-trapping assay featuring 1 base-pair (bp) precision.

273 rtant, highly variable, 5 million base-pair (bp) region where diploid assembly is particularly useful

274 lite sequences, including the 359-base-pair (bp) repeat sequence, recruited HP1a at the MBT.

275 es short paired-end tags (2 x 20 base pairs (bp)) to detect two genomic loci that are far apart on li

276 insert sequences of up to 2,049 base pairs (bp), including enhancers and promoters, into the rice ge

277 of intervention (difference -163 base pairs (bp), p=0.001).

278 Importantly, Hmo1 extended 20-50 base pairs (bp) downstream from Fhl1.

279 ble-stranded DNA (dsDNA) over 40 base pairs (bp) in length has been considered immunostimulatory.

280 pproximately 99% and length 6050 base pairs (bp) in the human genome, and 16 Tol2 elements of identit

281 protein (ZF6-DB) that targets 20 base pairs (bp) of a RHOcis-regulatory element (CRE) and demonstrate

282 nslocations have between 0 and 4 base pairs (bp) of microhomology (n = 26), short inserted sequences

283 ajority of the approximately 270 base pairs (bp) of vector space required for shRNA expression.

284 A 450 base pairs (bp) segment of cytochrome c oxidase subunit I (COI) was

285 ly bell-shaped with a peak at 50 base pairs (bp) upstream of the transcription start site (TSS) and 8

286 oligonucleotides longer than 20 base pairs (bp).

287 and deletion (5,464) calls >=50 base pairs (bp).

288 han or equal to approximately 60 base-pairs (bp) are required for DvSSJ1 insecticidal activity.

289 Hoogsteen DNA base pairs (bps) are an alternative base pairing to canonical Watson

290 double helix, Watson-Crick (WC) base pairs (bps) exist in dynamic equilibrium with sparsely populate

291 map since short reads of 50-100 base pairs (bps) from these regions map to multiple locations in ref

292 behind a footprint of up to five base pairs (bps) of the original VH gene that is often further obscu

293 Hoogsteen (HG) base pairs (bps) provide an alternative pairing geometry to Watson-C

294 and 40 thousand years (kyr) before present (bp), replacing all other forms of hominins.

295 going as far back as 7000 yr before present (bp).

296 PET acquisition at 180 s per bed position (s/bp).

297 te of cognitive control (in bits per second, bps) in the model fitting to estimate the capacity of co

298 and constricted C1'-C1' distance across the bp) to search for HG bps in X-ray structures of DNA dupl

299 ctivation of its core promoter, localized to bp -160 to +42 within the proximal 5' flanking region of

300 -5-FX interaction with FX-binding protein (X-bp) inhibited transduction in the presence of C57BL/6 se