ライフサイエンスコーパス: brain neuron

1 an RGS protein at the level of an individual brain neuron.

2 ain and retina, as well as isolated cultured brain neurons.

3 es, where Na(V)1.2 channels are expressed in brain neurons.

4 unit expressed in many but not all mammalian brain neurons.

5 nd VAPB defines ER-PM junctions in mammalian brain neurons.

6 2-AG accumulation in primary cultures of rat brain neurons.

7 extent of axonal regeneration of descending brain neurons.

8 a prenylated SNARE selectively expressed in brain neurons.

9 volved in survival and maintenance of mature brain neurons.

10 ther it also modulates Ca(2+) homeostasis in brain neurons.

11 ting the Kv1.2 localization observed in many brain neurons.

12 overed no coexpression of FRU(M) and 5-HT in brain neurons.

13 in the somatodendritic membrane of mammalian brain neurons.

14 ied on the basis of their rapid induction in brain neurons.

15 cesses, as well as during normal function of brain neurons.

16 nd immunolabels in mammalian cells including brain neurons.

17 in the spontaneously hypertensive rat (SHR) brain neurons.

18 ansduction pathway in Wistar Kyoto (WKY) rat brain neurons.

19 essed by using double labeling of descending brain neurons.

20 functional GLT-1 protein can be expressed in brain neurons.

21 and probably the developmental maturation of brain neurons.

22 and universally, with the number of cortical brain neurons.

23 d at specific subcellular sites in mammalian brain neurons.

24 ected electrogenic cells, such as individual brain neurons.

25 anogaster are regulated by about 75 pairs of brain neurons.

26 weight gradients of VPN outputs onto central brain neurons.

27 ociated with abnormal protein depositions in brain neurons.

28 The UBE3A gene is paternally imprinted in brain neurons.

29 of human PrP-WT and Y225A in the eye and in brain neurons.

30 tion of de novo glutathione synthesis in mid-brain neurons.

31 surements from a small population of central brain neurons.

32 e, consistent with its expression in central brain neurons.

33 thylation between retinal photoreceptors and brain neurons.

34 ons in regulating PtdIns lipid metabolism in brain neurons.

35 tization of the mu-opioid receptor (MOPr) in brain neurons.

36 reatment with lithium and VPA in primary rat brain neurons.

37 the soma and proximal dendrites of mammalian brain neurons.

38 gene LanCL1 that is prominently enriched in brain neurons.

39 eractions supply selenium for maintenance of brain neurons.

40 somatodendritic Ca(2+) signals in mammalian brain neurons.

41 e to hyperexcitability and hypersynchrony of brain neurons.

42 ts of hyperphosphorylated tau protein within brain neurons.

43 as TH1-AC1) and four newly identified local brain neurons.

44 odulation of ethanol inhibition of NMDARs in brain neurons.

45 ptors for estrogen in hypothalamic and other brain neurons.

46 ated receptor tyrosine kinase B signaling in brain neurons.

47 aling and Trk-mediated survival signaling in brain neurons.

48 re we show that Kv2.1 clusters on the AIS of brain neurons across diverse mammalian species including

49 on of newly freed time and a large number of brain neurons affordable on a cooked diet may thus have

50 AP was tested by observing Fos activation of brain neurons after olfactory threat cue in wild-type an

51 on, mu-opioid receptors were examined in rat brain neurons after treatment of animals with opioid dru

52 ricted subcellular localization in mammalian brain neurons, allowing for visualization and/or modulat

53 IP10 mRNAs were found to be expressed in rat brain neurons also expressing PAM proteins.

54 oth genes are coexpressed in most if not all brain neurons, although their patterns of expression var

55 arinic acetylcholine receptor subtype in the brain (neurons and glial cells; Br-M3-KO mice) showed a

56 xic foci in the lung (endothelial cells) and brain (neurons and neuropil).

57 different subtypes of Gi are involved in the brain neurones and in the endocrine cells: Gi2 in locus

58 receptors (mGluRs) are densely expressed in brain neurons and are actively involved in various cellu

59 (Nav) channels initiate action potentials in brain neurons and are primary therapeutic targets for an

60 hemoglobin chains are expressed in mammalian brain neurons and are regulated by a mitochondrial toxin

61 ATF5 is not detectably expressed by mature brain neurons and astrocytes, but is expressed by reacti

62 kinase is associated with sodium channels in brain neurons and can modulate Na(V)1.2 channels by tyro

63 generate electric rhythmicity in specialized brain neurons and cardiomyocytes.

64 ructural integrity of dendritic terminals in brain neurons and delay locomotor dysfunction.

65 lar specialization, shielding and nourishing brain neurons and glia while impeding drug delivery.

66 PEI mediates transgene expression in brain neurons and glia.

67 creased aneuploidy and apoptosis in the same brain neurons and glia.

68 trated the replication of a group 1 virus in brain neurons and glial cells and in cardiac myofibers.

69 glutamate-induced excitotoxicity in cultured brain neurons and in an animal model of cerebral ischemi

70 (PKA) decreases peak Na+ current in cultured brain neurons and in mammalian cells and Xenopus oocytes

71 agocytic lineage, pancreatic beta cells, and brain neurons and is activated under oxidative stress.

72 225A exhibit less toxicity in the eye and in brain neurons and less accumulation of insoluble PrP.

73 ith the inner side of the plasma membrane in brain neurons and rat PC12 cells in vitro; they are pres

74 CaMKK2 is highly enriched in brain neurons and regulates energy metabolism and neuron

75 xpression of nemuri in a small number of fly brain neurons and targeted it to the sleep-promoting, do

76 Here we describe four descending brain neurons and two with the soma in the subesophageal

77 d spatial manner with expression in specific brain neurons and visceral cell types.

78 ated PI3-kinase activity in both WKY and SHR brain neurons and was accompanied by its translocation f

79 d be due to axonal elongation by preexisting brain neurons and/or descending projections from new neu

80 dies of genomic DNA from the human and mouse brain, neurons and from mouse embryonic stem cells found

81 issues or cells in these body parts, such as brain, neurons and muscles, which have been identified a

82 and myoglobin, is expressed predominantly in brain neurons, and appears to modulate hypoxic-ischemic

83 odium channels initiate action potentials in brain neurons, and sodium channel blockers are used in t

84 ythmic expression of clock genes in specific brain neurons appears to control behavioral rhythms in a

85 Most brain neurons are active in waking, but hypothalamic neu

86 Finally, we show that brain neurons are necessary and sufficient for sensing a

87 ible assembly and binding of microtubules in brain neurons are regulated by charge-neutralizing phosp

88 In the adult mammalian brain, neurons are continuously generated in two structu

89 In the developing brain, neurons are produced from neural stem cells terme

90 -HT and 14-3-3 signaling pathways similar to brain neurons, are abnormal in SIDS.

91 hich initiate action potentials in mammalian brain neurons, are modulated functionally by cAMP-depend

92 neration for the total numbers of descending brain neurons as well as neurons in certain brain cell g

93 ides are surface glycolipids mainly found on brain neurons as well as peripheral nerves and skin mela

94 lly administered prolactin rapidly activates brain neurons, as evidenced by prolactin-induced phospho

95 ctive downregulation of L-VSCC expression in brain neurons at the same, lower concentrations.

96 One local brain neuron, B-LI4, received inhibitory as well as exci

97 Beginning in the early postnatal brain, neurons begin to aggregate near the ventricles of

98 or role in basal neurotransmitter release in brain neurons but contribute significantly after inducti

99 d a role as homophilic adhesion molecules in brain neurons, but the in vivo functions remain unknown.

100 Chronic stimulation of brain neurons by angiotensin II (Ang II) results in a in

101 ydroxylase and norepinephrine transporter in brain neurons by angiotensin II (Ang II).

102 including hepatocytes, skeletal muscle, and brain neurons by intravenous injection.

103 Selective overexpression of Nrf2 in brain neurons by lentiviral gene transfer was sufficient

104 channel could regulate synaptic efficacy in brain neurons by modulating Ca2+ levels in response to c

105 boration of dendrites among major classes of brain neurons by PKC-dependent mechanisms.

106 hat the control of excitatory and inhibitory brain neurons by type-1 cannabinoid (CB(1)) receptors is

107 We found that nuclear extracts from adult brain neurons can correct G.T and G.U mismatches, restor

108 e glucose metabolism becomes impaired in the brain, neurons can utilize glutamate as an alternative s

109 neurons (forming the vast majority of adult brain neurons) can be assigned to genetically and develo

110 diction results from adaptations in specific brain neurons caused by repeated exposure to a drug of a

111 Four collybistin isoforms are expressed in brain neurons; CB2 and CB3 differ in the C terminus and

112 ions in many locations, including subsets of brain neurons (clock neurons) within the central nervous

113 lar granule cells, which outnumber all other brain neurons combined.

114 Deletion of SOCS3 from brain neurons delays the onset of diet-induced infertili

115 intracellular [Ca(2+)](i) is altered in aged brain neurons during synaptically activated neuronal act

116 NF1-mutant human and mouse brain neurons elaborate midkine to activate naive CD8(+

117 hered 51 human and mouse DNA methylomes from brain neurons, embryonic stem cells and induced pluripot

118 cells inside the Hassall's corpuscles), and brain (neurons, ependymal cells, and macrophages) reveal

119 this fuel store is operational, even though brain neurons express the key regulatory enzymes associa

120 However, it remains unknown which brain neurons express TrkB to control body weight.

121 We show that the activity of two brain neurons expressing leucokinin neuropeptide is elev

122 Subsets of brain neurons expressing the clock genes period (per) an

123 In several areas of the macaque brain, neurons fire during delayed-response tasks at a r

124 The neurites of all brain neurons formed a ring-like branching pattern in th

125 Deep (239x) whole-genome sequencing (WGS) of brain neurons from 61 SCZ cases and 25 controls postmort

126 play an important role in the protection of brain neurons from ischemic and hypoxic injuries.

127 Then brain neurons from mice homozygous or heterozygous for t

128 r studies indicate that the Gr43a-expressing brain neurons function as a nutrient sensor for hemolymp

129 In the vertebrate brain, neurons grouped in parallel laminae receive disti

130 Across the brain, neurons had distinctive inter-spike interval dist

131 ve all in crustaceans, continuous genesis of brain neurons has also been shown, namely for soma clust

132 lase and norepinephrine transporter genes in brain neurons; however, the signal-transduction mechanis

133 we show that Drosophila ring neurons-central brain neurons implicated in navigation-display visual st

134 c treatment with VDH was reported to protect brain neurons in both aging and animal models of stroke.

135 serotonergic phenotypic traits in developing brain neurons in culture.

136 Excessive inhibition of brain neurons in primary or slice cultures can induce ho

137 t unique sequences in PRO1- and PRO2-labeled brain neurons in situ, indicative of bicistronic gene ex

138 rizing the effects of stimulating individual brain neurons in the isolated nervous system of the leec

139 ide, similar to what is believed to occur in brain neurons, in the initial phases of AD.

140 of 49% and 68%, respectively, of descending brain neurons, including many unidentified RS neurons, w

141 demonstrate that the majority of descending brain neurons, including small, unidentified RS neurons,

142 Select brain neurons increase their firing rate when ambient gl

143 ight facilitates MIP secretion from specific brain neurons innervating pdf neurons.

144 Accumulation of beta-amyloid (Abeta) inside brain neurons is an early and crucial event in Alzheimer

145 that CB1 receptor signaling in many specific brain neurons is dispensable for the acute hypophagic ef

146 Light-responsive neural activity in central brain neurons is generally conveyed through opsin-based

147 ate that anandamide internalization in mouse brain neurons is independent of FAAH activity.

148 In brain neurons, it was found that active long intersperse

149 contrary to the current orthodox model that brain neurons just integrate and fire under accompanimen

150 cardiac pacemaker cells and diverse types of brain neurons, key channel properties are still elusive.

151 er, although DPP10 is also expressed in some brain neurons lacking Kv4 (such as parvalbumin- and soma

152 r, knockdown of XRCC1 in primary human fetal brain neurons leads to enhanced sensitivity to menadione

153 function in cultured human neurons or murine brain neurons leads to LD and triglyceride accumulation.

154 CB(1) receptor deletion from GABAergic brain neurons led to the opposite phenotype, characteriz

155 neuronal tissues, including a set of lateral brain neurons (LNs) that mediate rhythms in locomotor ac

156 and parrots have much higher proportions of brain neurons located in the pallial telencephalon compa

157 lomegaly, posterior fossa anomalies, loss of brain neurons; lumbar CSF leakage, hindlimb somatosensor

158 In mammalian brain neurons, membrane depolarization leads to voltage-

159 ce activating NF-kappaB cascade, a couple of brain neurons modulate a specific octopamine-dependent b

160 ila has defined two populations of circadian brain neurons, morning cells (M-cells) and evening cells

161 ceptor (RyR) Ca2+ -release channels in mouse brain neurons, most prominently in medium spiny neurons

162 al lamprey, the large, identified descending brain neurons (Muller and Mauthner cells) are capable of

163 re caused by a heterogeneous degeneration of brain neurons not only in substantia nigra pars compacta

164 o etiological neuroinflammatory responses by brain neurons of neuropsychiatric diseases.

165 duct of the Drosophila period (per) gene, in brain neurons of the adult fly are strongly involved in

166 Brain neurons of these mice, however, did not show TDP-4

167 In both mammals and flies, circadian brain neurons orchestrate physiological oscillations and

168 In brain neurons, P- and Q-type Ca(2+) channels both appear

169 roup of sexually dimorphic GABAergic central brain neurons, popularly known as mAL, in aggression reg

170 ginning at 16 days post coitum in developing brain neurons, primitive inner ear cells, and seminifero

171 d lamprey, axonal regeneration of descending brain neurons probably contributes significantly to the

172 e how changes in activity of GABA(+) central brain neurons processing pheromonal information, such as

173 But how central brain neurons processing this information modulate aggre

174 In the brain, neurons produce Abeta by the proteolytic processi

175 arval lamprey, significantly more descending brain neurons projected to specific rostral levels of th

176 In the Drosophila brain, neurons projecting to the dorsal fan-shaped body

177 suppress eye toxicity, reduce cell death in brain neurons, protect the structural integrity of dendr

178 Moreover, genetic control over gut-to-brain neurons provides a molecular framework for underst

179 cent stain that labels injured, degenerating brain neurons, quantifies the extent of hippocampal inju

180 l lamprey, axonal regeneration by descending brain neurons, rather than the relatively slow addition

181 covery of locomotor behavior, and descending brain neurons regenerate their axons for progressively g

182 cent work has identified sensory and central brain neurons required for larval visual behaviors, incl

183 All brain neurons responded phasically to the sound pulses o

184 Starting from 5 months, brain neurons showed enlarged, structurally abnormal mit

185 named this antibody AmBNSab (Apis mellifera Brain Neurons Specific antibody).

186 sic action, we generated a mutant mouse with brain neuron-specific reductions in P450 activity; these

187 To delineate insulin actions in the brain, neuron-specific insulin receptor knockout (NIRKO)

188 The distribution of these PRV-labeled brain neurons strongly resembled that obtained after the

189 of postnatal cell death in several different brain neuron subtypes.

190 However, smaller, unidentified descending brain neurons, such as many of the reticulospinal (RS) n

191 elin and LGI1 co-localize in a subset of rat brain neurons, supporting an involvement of both protein

192 the soma and proximal dendrites of mammalian brain neurons, tethering the plasma membrane (PM) to end

193 ic opiate use produces persistent changes in brain neurons that are expressed as adverse effects, inc

194 rectly communicates metabolic information to brain neurons that control reproduction, using GABAergic

195 oendocrine cells rapidly excites a subset of brain neurons that express Dh31 receptor (Dh31R).

196 isease, and are among the few populations of brain neurons that express p75NTR throughout life.

197 trigeminal sensory fibers made synapses with brain neurons that have direct or indirect inputs to ret

198 ring the development of a lineage of central brain neurons that innervate the optic lobes and are req

199 ptide Diuretic hormone 31 (DH31) produced by brain neurons that project into the CA plays an essentia

200 leuc and lkr genes identify small groups of brain neurons that regulate this behavior.

201 Our results demonstrate in adult mouse brain neurons that the mPTP functions to enhance ROS pro

202 l of the two kidneys is provided by the same brain neurons, the central circuitry involved in the inn

203 o acid catabolism and ammoniagenesis; and in brain neurons, the maintenance of glutamate neurotransmi

204 expression was observed in 3-4 pairs of the brain neurons: the anterior dorso-lateral interneurons,

205 These brain neurons therefore contain an identified deep brain

206 Gut-derived Dh31 excites the brain neurons through the circulatory system within a fe

207 pacity of nuclear extracts from adult rodent brain neurons to carry out DNA mismatch repair.

208 asing hormone (GnRH)-mediated signaling from brain neurons to pituitary gonadotropes.

209 ated axons can electrically couple groups of brain neurons to synchronise fi ring and contribute to r

210 ly sends new cells to different areas of the brain: neurons to the olfactory bulbs and glial cells to

211 stitute a dominant Ca(2+) entry pathway into brain neurons, triggering downstream Ca(2+) -dependent p

212 ional tissue-specific expression of ttll1 in brain neurons, ttll4 in muscle, and ttll7 in otic placod

213 Finally, silencing a dopaminergic brain neuron type impairs anemotaxis.

214 Here, we show that in brain neurons type I PKA is directed to Kv2.1 channel-de

215 retinal ganglion cell (RGC) types to diverse brain neuron types remains unknown.

216 ses serotonin-immunoreactivity in identified brain neurons under limiting food conditions thereby lea

217 esent necrosis, but it now appears that many brain neurons undergo apoptosis after either global or f

218 Brain neurons utilize the primary cilium as a privileged

219 In the rodent brain, neurons vary significantly in katanin levels, dep

220 that conditioning lesions "prime" descending brain neurons via cell body responses and enhance subseq

221 dish peroxidase (HRP) labeling of descending brain neurons was performed in "young" and "old" larval

222 ysis of public single nuclei data from adult brain neurons, we detected an extrachromosomal circular

223 n polymerization in Alzheimer's disease (AD) brain neurons, we examined protein and gene expression f

224 nd artificial activation of Gr43a-expressing brain neurons, we show that Gr43a is both necessary and

225 d at 20% BL, an average of 98% of descending brain neurons were double labeled.

226 Voltage-gated sodium channels in brain neurons were found to associate with receptor prot

227 evious reports of PTHrP expression in normal brain, neurons were the primary site of immunoreactive P

228 that manipulating PDF signaling in eya+ fly brain neurons, where EYA and PDF receptor are co-express

229 etermine the neurochemical identities of rat brain neurons which are activated by a low dose (0.175 m

230 e a tradeoff between body size and number of brain neurons, which explains the small brain size of gr

231 approximately three to five GABA(+) central brain neurons with anatomical similarities to mAL.

232 la kinesin-5, Klp61F, is expressed in larval brain neurons, with high levels in ventral nerve cord (V

233 Most recent projects focus on only brain neurons, with the exception of an early effort to

234 een attributed to peripheral ppk and central brain neurons, with the former serving as hypothetical i

235 does not have a relatively larger number of brain neurons yet is remarkable in its cognitive abiliti