ライフサイエンスコーパス: brain-dead

1 y significantly compared with donation after brain dead.

2 and simple behavioral tests (best = 100 and brain dead = 0).

3 A brain-dead adult decedent underwent bilateral native nep

4 70 years or younger who is legally declared brain dead and does not exhibit any excluding factors) w

5 d lung grafts from donors that were rendered brain dead and mechanically ventilated for 4 h before pr

6 ents: PATIENTS < or = 70 yrs of age who were brain dead and medically suitable for donation.

7 f genes associated with inflammation in both brain-dead and sham subjects relative to naive controls.

8 ining treatments, 30 (16%) were diagnosed as brain dead, and 26 (14%) died following an unsuccessful

9 all 78 patients (10%) who died qualified as brain dead; and 81% of all patients (63 of 78) who died

10 Tracheotomized brain-dead animals and anesthetized controls were mechan

11 etrospective study suggests that organs from brain-dead avalanche victims can be transplanted with go

12 Non-brain dead (BD) donors served as controls.

13 incipal reason lungs from otherwise eligible brain dead (BD) organ donors are not transplanted.

14 Deciding about the organ donation of one's brain-dead beloved often occurs in an unexpected and del

15 The success rate of transplanted organs from brain-dead cadaver donors is consistently inferior to th

16 atients with severe brain injury who are not brain-dead can donate organs after they are removed from

17 nonutilization rate in both entire cases and brain-dead cases.

18 ed bilateral native nephrectomies in a human brain-dead decedent and subsequently transplanted two ki

19 a national cohort of all US adult, deceased brain dead donor, isolated livers available for transpla

20 o norepinephrine in managing the hypotensive brain dead donor.

21 lating CD4+ cells in the HIV-negative (HIV-) brain-dead donor (BDD) is not known.

22 f sC5b-9 from the reperfused kidney graft in brain-dead donor and cardiac dead donor kidney transplan

23 n 3 hours after placement and reperfusion of brain-dead donor grafts, significant neutrophil infiltra

24 cytokines was significantly increased in all brain-dead donor grafts.

25 uri, performed the first organ recovery of a brain-dead donor in a hospital-independent, free-standin

26 This complex process was accelerated in brain-dead donor kidneys.

27 living donor liver transplantation (LDLT) or brain-dead donor liver transplantation (BDLT) across 5 F

28 study was to examine the effect of HR on the brain-dead donor on the number of organs transplanted pe

29 Living and brain-dead donor strategies are not mutually exclusive a

30 A brain-dead donor strategy is more acceptable from an eth

31 Compared with a brain-dead donor strategy, a living donor strategy offer

32 in vivo significance, we used a novel murine brain-dead donor transplant model.

33 Long-term survival of brain-dead donor transplants was significantly less than

34 er transplantation with a liver graft from a brain-dead donor whose cause of death was not hanging or

35 ical kidney transplantation in living donor, brain-dead donor, and cardiac dead donor kidney transpla

36 The donor was a 20-year-old nulliparous brain-dead donor.

37 rom DCD donors compared to 89.6%, 64.8% from brain dead donors (DBD) (P = 0.7).

38 ere compared with liver grafts from standard brain dead donors (n = 50), also matched to the balance

39 swine transplanted with lung allografts from brain dead donors all rejected their grafts by postopera

40 h allografts and isografts from normotensive brain dead donors and anesthetized LD.

41 Over a period of 10 months, 23 consecutive brain dead donors screened for liver procurement underwe

42 normotension, the transplanted kidneys from brain dead donors showed a significantly longer interval

43 We report 2 transplants with kidneys from brain dead donors with known DIC.

44 nors without a heartbeat (DWHB), 55,206 were brain dead donors, and 1,298 were unspecified donors.

45 nization-reported eligible deaths (potential brain-dead donors </= 70 yr of age) from January 1, 2008

46 ese expression levels with those observed in brain-dead donors (BDD).

47 Ds were compared with those procured from 10 brain-dead donors (BDDs).

48 had longer hepatectomy times than those from brain-dead donors [50 minutes (35 to 68) vs 40 minutes (

49 Of 10,292 consecutive brain-dead donors analyzed, 701 received three-drug HR.

50 Hormonal resuscitation stabilizes certain brain-dead donors and is associated with significant inc

51 HR stabilizes certain brain-dead donors and is associated with significant inc

52 ually the front-line providers for potential brain-dead donors and their next-of-kin, and these data

53 Kidneys from brain-dead donors are cold preserved until transplanted.

54 Brain-dead donors are moved within hours of authorizatio

55 dy suggests that a preoperative selection of brain-dead donors based on a combination of both Control

56 tion significantly increased in kidneys from brain-dead donors before storage and after 4 hr of reper

57 s that develop within kidney allografts from brain-dead donors could be normalized using a recombinan

58 Animals bearing kidneys from brain-dead donors died of renal failure secondary to acu

59 after first adult lung transplantation from brain-dead donors done between July 1, 1999, and Dec 31,

60 sibility and incidence of organ retrieval in brain-dead donors following cardiorespiratory arrest due

61 the pros and cons of using living donors or brain-dead donors in uterus transplantation programs, 2

62 Splitting of livers from appropriate brain-dead donors into right and left lobes is technical

63 However, the yield of pancreatic islets from brain-dead donors is negatively affected by the up-regul

64 Acute rejection evolved in hearts from brain-dead donors more intensely and at a significantly

65 f interventions to stabilize hemodynamics in brain-dead donors or to improve organ function and outco

66 polation of these probabilities to the 5,921 brain-dead donors recovered in 2001 was calculated to yi

67 A retrospective analysis of all brain-dead donors recovered in the United States from Ja

68 Additionally, lung utilization rates from brain-dead donors remain substantially lower compared wi

69 This study suggests that 3HR treatment of brain-dead donors results in increased numbers of transp

70 s of the proteomic signature of kidneys from brain-dead donors revealed large-scale changes in mitoch

71 ultivariate studies on hormonal treatment of brain-dead donors revealed significant increases in orga

72 ecision making by the relatives of potential brain-dead donors reveals possibilities for improving th

73 expression of key inflammatory mediators in brain-dead donors should be evaluated as a new approach

74 Nonfailing hearts from brain-dead donors show marked differences in circadian c

75 n in samples recovered from nonheart failure brain-dead donors showed acrophase shifts, or weak or co

76 tively steatosis and fibrosis in livers from brain-dead donors to be potentially used for transplanta

77 e obtained in patients receiving organs from brain-dead donors under standard procurement techniques.

78 A total of 83 219 brain-dead donors were included and were randomly divide

79 Changes in isografts from brain-dead donors were less marked and developed at a sl

80 inferior outcomes after lung transplant from brain-dead donors who have had a period of cardiac arres

81 Of the 852 brain-dead donors who underwent randomization, 838 were

82 without heartbeats in addition to those from brain-dead donors with beating hearts.

83 All liver grafts from brain-dead donors with RLT proposed for LT between 2010

84 Only using brain-dead donors with standard criteria, the existing d

85 pare the safety and efficacy of preoperative brain-dead donors' treatment with the intragastric admin

86 ion after circulatory death [DCD] and 3 from brain-dead donors), median Donor Risk Index 2.15, were s

87 sent rates for organ donation from potential brain-dead donors, and to identify factors associated wi

88 ecision making of the relatives of potential brain-dead donors, its evaluation, and the factors influ

89 of 4,543 recipients of hearts recovered from brain-dead donors, reported to the United Network for Or

90 to stabilize and improve cardiac function in brain-dead donors.

91 are comparable to outcomes from contemporary brain-dead donors.

92 instability and poor organ perfusion in many brain-dead donors.

93 are similar to those of LT using grafts from brain-dead donors.

94 an be mobilized and collected from the PB of brain-dead donors.

95 livers utilized in transplantation come from brain-dead donors.

96 raft viability compromises retrieval in most brain-dead donors.

97 s acquired from the nonfailing ventricles of brain-dead donors.

98 re performed at outside institutions, all on brain-dead donors.

99 interventions focusing on the management of brain-dead donors.

100 rial of preload optimization is warranted in brain-dead donors.

101 Brain-dead Fisher rats were treated for 6 hours with eit

102 systolic and diastolic LV/RV function in the brain-dead, heart-beating cadaver, which may contribute

103 he host's blood over a 61-day procedure in a brain-dead human (decedent) recipient.

104 e transplant a gene-edited pig kidney into a brain-dead human recipient on pharmacologic immunosuppre

105 igs, we transplanted porcine hearts into two brain-dead human recipients and monitored xenograft func

106 from pigs remained viable and functioning in brain-dead human recipients for 54 hours, without signs

107 rom these genetically modified pigs into two brain-dead human recipients whose circulatory and respir

108 s transplanted from 10-gene-edited pigs into brain-dead human recipients.

109 Brain-dead human subjects (decedents) were recently intr

110 A1-knockout, GTKO) pig into a nephrectomized brain-dead human using clinically approved immunosuppres

111 logy of a porcine kidney transplanted into a brain-dead human with kidney failure, demonstrating life

112 t (CA) causes renal ischemia in one-third of brain-dead kidney donors before procurement.

113 In a multicenter randomized clinical trial, brain-dead kidney donors deemed to be low risk and not r

114 s in the United States, we randomly assigned brain-dead kidney donors to undergo therapeutic hypother

115 st that, in low-risk non-pumped kidneys from brain-dead kidney donors, therapeutic hypothermia compar

116 In the current setting of organ shortage, brain-dead liver donors with recent liver trauma (RLT) r

117 ited pig was transplanted into a 39-year-old brain-dead male human recipient following a brain hemorr

118 Brain-dead (n = 12) and sham (n = 5) rhesus macaques wer

119 Compared with kidneys from neurologically brain dead (NBD) donors, DCD kidneys had a higher adjust

120 cipients sustained by kidney allografts from brain-dead, normal anesthetized, and anesthetized ventil

121 Outcomes using advanced age brain-dead or cardiac-dead donor kidneys are similar.

122 ere obtained from patients who were declared brain-dead or had emergent splenectomy due to trauma; co

123 kinje potential prevalence) were examined in brain dead (or Sham, nonneurological injury) sheep donor

124 f the allograft, for example, from a living, brain-dead, or circulatory death donor, influences the i

125 Conditioning the brain-dead organ donor by altering metabolism could be a

126 of organ function in the critically unstable brain-dead organ donor to salvage organs for transplanta

127 ungs, intestines) sites from a population of brain-dead organ donors (2 months-93 years; n = 291) acr

128 We recruited 30 consecutive brain-dead organ donors and 78 recipients between April

129 the inflammatory response characteristics in brain-dead organ donors and examine associations with or

130 Preload responsiveness is common in brain-dead organ donors and is associated with higher in

131 y specimens from the costal diaphragms of 14 brain-dead organ donors before organ harvest (case subje

132 size and composition of the national pool of brain-dead organ donors during a three-year period and,

133 Therapeutic hypothermia in brain-dead organ donors has been shown to reduce delayed

134 a recent trial, targeted mild hypothermia in brain-dead organ donors significantly reduced the incide

135 replacement therapy is administered to many brain-dead organ donors to improve hemodynamic stability

136 Diaphragm and biceps specimens obtained from brain-dead organ donors who underwent MV (15-176 h) and

137 Among brain-dead organ donors, older age donors contribute few

138 Among brain-dead organ donors, therapeutic hypothermia was inf

139 Using functional hemodynamic monitoring in brain-dead organ donors, we test the hypothesis that don

140 Upper limbs were procured from brain-dead organ donors.

141 The first paradox is the brain dead patient whose 'phenotype' betrays the ultimat

142 Family members of brain dead patients experience an unprecedented situatio

143 recent controversies over the assessment of brain dead patients into a scientific and wider societal

144 cerebellum level were significantly lower in brain-dead patients (p = 0.019 for HC-WM, p < 0.001 for

145 Seventeen brain-dead patients and 20 control patients undergoing p

146 Pneumonia occurs in one-third of brain-dead patients and appears as the main reason for l

147 1.52-2.21; p < 0.001), care of relatives of brain-dead patients as complex (odds ratio, 1.59; 95% CI

148 During the study period, there were 22,270 brain-dead patients diagnosed in France, of whom 161 wit

149 Brain-dead patients had higher serum concentrations of T

150 Immunohistochemical analyses showed that brain-dead patients had increased TNF protein levels com

151 Ten brain-dead patients had significantly decreased low-freq

152 and showed that desmopressin administered to brain-dead patients was not advantageous with respect to

153 All non-brain-dead patients who became non-heart-beating organ d

154 lute contraindication to organ donation from brain-dead patients who have sustained a fatal ingestion

155 4) concentrations when compared with six non-brain-dead patients with a Glasgow Coma Scale score of 3

156 All brain-dead patients with multiorgan trauma, including li

157 Brain-dead patients with ongoing extracorporeal membrane

158 Brain-dead patients with ongoing extracorporeal membrane

159 e organ procurement organization, caring for brain-dead patients, managing a candidate for donation a

160 ipidus, an almost universal occurrence among brain-dead patients, on hepatic function.

161 arts were obtained from 12 transplant and 13 brain-dead patients.

162 dence-based, goal-directed checklist reduced brain-dead potential donor loss to cardiac arrest.

163 Consecutive brain-dead potential donors in the ICU aged 14 to 90 yea

164 ntion group were instructed to administer to brain-dead potential donors in the intervention group an

165 Among the 1771 brain-dead potential donors screened in 63 hospitals, 15

166 The primary outcome was loss of brain-dead potential donors to cardiac arrest at the ind

167 ness of goal-directed care to reduce loss of brain-dead potential donors to cardiac arrest is unclear

168 igned to the intervention group (743 [48.4%] brain-dead potential donors) and 32 (50.8%) to the contr

169 32 (50.8%) to the control group (792 [51.6%] brain-dead potential donors).

170 In hemodynamically unstable brain-dead potential heart donors, intravenous levothyro

171 Hormonal therapy to the brain-dead potential organ donor can include thyroid hor

172 ine administration of thyroid hormone in the brain-dead potential organ donor.

173 We identified a total of 18,524 brain-dead potential organ donors during the study perio

174 The predicted annual number of brain-dead potential organ donors is between 10,500 and

175 organ-procurement organizations to identify brain-dead potential organ donors.

176 cribing administration of thyroid hormone to brain-dead potential organ donors.

177 commendations regarding organ support of the brain-dead pregnant woman are reviewed.

178 radiol (E2) treatment on the lungs of female brain dead rats.

179 Hearts from brain-dead rats (Fisher, F344) were rejected significant

180 ve and antioxidative processes in kidneys of brain-dead rats after fast and slow BD induction.

181 Healthy non-brain-dead rats served as reference values.

182 ated), rats subjected to rapid-onset BD, and brain-dead rats treated with E2 (280 ug/kg, intravenous)

183 Brain-dead rats were monitored for 0.5, 1, 2, or 4 hours

184 cally modified cardiac xenografts in legally brain-dead recipients, representing a novel experimental

185 inical human xenotransplantation models with brain-dead recipients.

186 DCD were compared with other type of grafts (brain dead, split, and living donor).

187 Donors were stratified by DCD or brain dead status and by AKI stage.

188 tically engineered (GE) porcine kidneys into brain-dead subjects and a small number of ESRD patients

189 Hemoadsorption for removal of cytokines in brain-dead subjects is feasible.

190 ized, open-label, feasibility study in which brain-dead subjects were randomized to two treatment gro

191 One patient became brain dead; the condition of two patients subsequently i

192 d criteria donor kidneys from donors who are brain dead using end-HMPo2 after SCS does not improve gr

193 Patients were excluded if they were declared brain dead, were organ donors, required high-frequency v