ライフサイエンスコーパス: brush border

1 collection of apical microvilli known as the brush border.

2 mice became stunted, and enterocytes lacked brush border.

3 splaying an intact polarization with regular brush border.

4 d an apical array of microvilli known as the brush border.

5 accumulated in villi and at the base of the brush border.

6 position and highly ordered structure of the brush border.

7 mble their apical microvilli into an ordered brush border.

8 n of intermediate filament proteins into the brush border.

9 e processing and transporting factors in the brush border.

10 ctin from cortical lateral networks into the brush border.

11 bules of endocytic compartments in the renal brush border.

12 f microvilli, which pack tightly to form the brush border.

13 ve with normal human kidney proximal tubular brush border.

14 philic adhesion complexes help stabilize the brush border.

15 htly packed array of microvilli known as the brush border.

16 formed proteomic analysis on WT and Myo1a KO brush borders.

17 ic protein receptors from porcine intestinal brush borders.

18 n reminiscent of that observed at PACSIN2 KO brush borders.

19 ther, and ultimately clustering to form the "brush border."

20 In addition, the brush-border alkaline phosphatase was reduced as was exp

21 These studies revealed that WT brush borders also contain the short-tailed class I myos

22 One defining feature is the brush border, an array of microvilli that serves to ampl

23 cal surface during differentiation to form a brush border: an array of actin-supported membrane protr

24 trols genes required to construct the apical brush border and absorb nutrients, including dietary lip

25 Uptake is slower than at the brush border and although, as in the brush border, uptak

26 t IF reporters localize below the actin-rich brush border and are highly enriched in the lumen-envelo

27 to continuous FSS also acquired an extensive brush border and basolateral membrane invaginations rese

28 se found in the microvilli of the intestinal brush border and kidney.

29 istopathological assessment revealed loss of brush border and lipid vacuolation in the renal cortex o

30 IIA localized to the basal cortex and apical brush border and mediated MHCI internalization from the

31 gnaling molecules cosediment with megalin in brush border and microvillar fractions.

32 ositioned at the interface between the stiff brush border and soft cytoplasm suggesting a mechanical

33 by using 24-well plates coated with purified brush borders and purified microvilli.

34 duodenal enterocytes in control rats and on brush-border and basolateral membrane domains in iron-de

35 protein levels are dramatically increased in brush-border and basolateral membrane vesicles isolated

36 nterocytes, M cells lack an organized apical brush border, and are able to transcytose microparticles

37 ytoskeletal and membrane components from the brush border, and redistribution of intermediate filamen

38 ges (vacuolization of tubular cells, loss of brush border, and tubular cell swelling) were each obser

39 detected Klotho in the proximal tubule cell, brush border, and urinary lumen, where phosphate homeost

40 of microvilli in both kidney and intestinal brush borders, and loss of Myo7b in differentiating inte

41 ncrease in the NHE3 mobile fraction from the brush border; and was accompanied by a NHERF2 ezrin-radi

42 We postulate that antibodies to brush border antigens cause direct epithelial injury, ac

43 ointerstitial nephritis due to antibodies to brush border antigens of the proximal tubule has been de

44 eleton following treatment with anti-tubular brush-border antiserum (anti-Fx1A).

45 ding, we found that the abundance of AQP1 in brush border apical and basolateral membranes was augmen

46 to the apical domain of enterocytes to drive brush border assembly and identifies a point of function

47 data reveal an adhesion-based mechanism for brush border assembly and illuminate the basis of intest

48 tion of CALML4 within enterocytes results in brush border assembly defects that mirror the loss of ot

49 Finally, the acceleration in brush border assembly induced by Arp2/3 inhibition was a

50 We found that brush border assembly is driven by the formation of Ca(2

51 Thus, brush border assembly is limited by G-actin availability

52 In a cell culture model of brush border assembly, Arp2/3 inhibition accelerated the

53 udy uncovers an essential role for ANKS4B in brush border assembly, reveals a hierarchy in the molecu

54 uired for the scaffold to target and mediate brush border assembly.

55 tor, to increase G-actin availability during brush border assembly.

56 isrupts intermicrovillar adhesion and, thus, brush border assembly.

57 hrough hydrolysis of the phosphate esters by brush border-associated enzymes, leading to a high conce

58 Higher magnification revealed well-developed brush borders at the apical side of the tissue.

59 icrovillar lipid rafts, was missing from the brush border (BB) in cells expressing this fragment.

60 xchanger 3 (NHE3) and is associated with the brush border (BB) membrane of murine kidney and small in

61 or cordon bleu (COBL) promotes the growth of brush border (BB) microvilli.

62 identifies calpain as being instrumental for brush border (BB) microvillus assembly during differenti

63 The epithelial brush border (BB) Na(+)/H(+) exchanger 3 (NHE3) accounts

64 ed that approximately 25-50% of rabbit ileal brush border (BB) Na(+)/H(+) exchanger NHE3 is in lipid

65 The brush border (BB) Na(+)/H(+) exchanger NHE3 is rapidly a

66 The intestinal and renal proximal tubule brush border (BB) Na+-H+ exchanger NHE3 binds to members

67 ine, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface.

68 nt within the microvillus (MV) of the apical brush border (BB) where it forms lateral tethers between

69 Within microvilli of the enterocyte brush border (BB), myosin-1a (Myo1a) forms an ordered en

70 sed on physiological studies, the epithelial brush-border (BB) Na+/H+ antiporter3 (NHE3) seems to ass

71 To investigate the possible role of a brush border beta-glucosidase in the hydrolysis of PNG,

72 ted targeting sequence coupled with in vitro brush border binding assays suggests that it functions a

73 8 in mice also disrupted the assembly of the brush border, but ezrin distributed away from the apical

74 fR1 mediates hTf uptake across the PT apical brush border, but in conditions of decreased cellular ir

75 edulla displaying cell necrosis, loss of the brush border, cast formation and tubular dilatation in W

76 Klf5(Delta/Delta) fetuses lacked the apical brush border characteristic of enterocytes, and a loss o

77 thelial cells, leading to the formation of a brush border containing microvilli on the apical surface

78 n of villin, an actin-binding protein of the brush border cytoskeleton.

79 s by beta-MCD jettisoned the D(1) R from the brush border, decreased sodium excretion, and increased

80 nal epithelium in maximizing flow-activated, brush border-dependent, transcellular salt and water rea

81 d extracellular adhesion to shape the apical brush border domain.

82 vivo or inadequate nutrient exposure to the brush border due to small intestinal dysmotility.

83 olved in Map-induced filopodia formation and brush border elongation on infected HeLa and Caco-2 cell

84 ipopolysaccharide were reduced in Caco2-BBE (brush border enterocyte) cells exposed to NP-KPV compare

85 Duodenal mucosal histology and expression of brush border enzyme dipeptidyl peptidase IV and peptide

86 ncreatic triglyceride lipase, and intestinal brush border enzyme, phospholipase B.

87 we examined the role of the small intestinal brush-border enzyme, intestinal alkaline phosphatase (IA

88 and in vivo models, we demonstrate that the brush-border enzyme, intestinal alkaline phosphatase (IA

89 further digestion of a gliadin by intestinal brush border enzymes and is a highly specific substrate

90 The brush border enzymes DPPIV and sucrase-isomaltase still

91 design, allowing for cleavage by the kidney brush border enzymes of the CPP before uptake by proxima

92 illar membrane, contain catalytically active brush border enzymes, and are specifically enriched in i

93 ferentiated intestinal epithelium, including brush border enzymes, polarization, and tight junctions.

94 teroendocrine cells), presence of functional brush-border enzymes (lactase, sucrase-isomaltase and di

95 and SI are anchored to the small intestinal brush-border epithelial cells, and each contains a catal

96 a protein found in the actin bundles of the brush border epithelium, is of interest both as a compac

97 ignificantly reduced NHE3 basal activity and brush border expression in Caco-2BBe cells.

98 These studies indicated that, although brush border expression of NHE3 was unaffected by the lo

99 In conclusion, epithelial MLCK-activated brush border fanning by IFN-gamma promotes adherence and

100 ht chain phosphorylation, arc formation, and brush border fanning coincided with intermicrovillous ba

101 a caused MLCK-dependent TW arc formation and brush border fanning, which preceded caveolin-mediated b

102 nase (MLCK) in TW myosin phosphorylation and brush border fanning.

103 To understand brush border formation, we used live cell imaging to vis

104 but did affect epithelial morphogenesis and brush border formation.

105 of the apical microvilli were induced as the brush border formed during polarization; as barrier func

106 tose, was accompanied by marked increases in brush border GLUT5 abundance, and was blocked by RU486.

107 in, and knockdown of this factor compromised brush border growth in a concentration-dependent manner.

108 Effects on brush border growth were rescued by treatment with the G

109 oxin (STa) to its receptor on the intestinal brush border, guanylyl cyclase type C (GC-C).

110 ed the safety factor of the mouse intestinal brush-border hydrolase maltase in series with the glucos

111 The duodenal epithelial brush border IAP-P2Y-HCO(3-) surface microclimate pH reg

112 PepT1 is abundant along the small-bowel brush border in humans; expression in the colon indicate

113 e of which (NHERFs 1-3) are localized to the brush border in kidney and intestinal epithelial cells.

114 ti-AgALP serum localized AgALP to the apical brush border in the anterior and posterior midgut of lar

115 n caspase-3 activity, tubular apoptosis, and brush border injury (BBI) in mouse kidneys.

116 whereas the Txp group demonstrated only mild brush border injury without apoptosis or necrosis.

117 vacuoles, nuclear count, and proximal tubule brush border integrity, which was validated with immunoh

118 differentiation, as revealed by the lack of brush border intestinal alkaline phosphatase activity, t

119 Preliminary studies of enterocyte brush-border ion transporter proteins (sodium hydrogen e

120 AgCad1 in the larval brush border is a binding protein for Cry4Ba toxin.

121 Assembly of the brush border is controlled by the intermicrovillar adhes

122 Although the brush border is essential for physiological homeostasis,

123 e most abundant components of the enterocyte brush border is the actin-based monomeric motor, myosin-

124 e II transmembrane protein of the enterocyte brush border, is sorted directly to the apical membrane

125 +)/H(+) exchanger 3 (NHE3) is the epithelial-brush border isoform responsible for most intestinal and

126 e whether PDZK1 interaction is essential for brush border localization of NHE3 and CFEX in vivo, we e

127 ly, the treatment strategy prevented tubular brush border loss, diminished tubular iron deposition, b

128 Here we show that Fas2 is essential to brush border maintenance in renal tubules of Drosophila.

129 Brush-border maltase-glucoamylase (MGA) activity serves

130 well as epithelial markers and a PT-enriched brush border marker Ggt1.

131 tered KBrO(3) on redox status and enzymes of brush border membrane (BBM) and carbohydrate metabolism

132 human intestinal biopsies revealed increased brush border membrane (BBM) and decreased cytoplasmic DM

133 lotting revealed a 56 +/- 6% decrease in the brush border membrane (BBM) expression of mURAT1 in NHER

134 The epithelial brush border membrane (BBM) Na(+)-H(+) exchanger 3 (NHE3

135 or (EGF) stimulation of Na absorption by the brush border membrane (BBM) Na(+)/H(+) exchanger NHE3.

136 chronically inflamed rabbit small intestine, brush border membrane (BBM) Na-glutamine co-transport is

137 The apical brush border membrane (BBM) of intestinal epithelial cel

138 , and ezrin, was decreased in the intestinal brush border membrane (BBM) of mice with streptozotocin-

139 anion transporter 1 (PAT1)] exchange in the brush border membrane (BBM) of villus cells.

140 nd the uptake of these lipids in vitro using brush border membrane (BBM) vesicles.

141 se from the proximal tubule lumen across the brush border membrane (BBM) via a sodium-dependent trans

142 alent metal ions across the small-intestinal brush border membrane (BBM).

143 B1 phenylalanine permitted it to bind to the brush border membrane and greatly enhanced its hypoglyce

144 A scavenger receptor (type BI) in the brush border membrane appears to facilitate cholesterol

145 are transported across the ileal enterocyte brush border membrane by the well characterized apical s

146 single nephrotoxic dose of KBrO(3) inhibits brush border membrane enzymes, induces oxidative stress

147 The AgCad1 protein was present in brush border membrane fractions prepared from larvae, an

148 ce expression of AQP1 in the proximal tubule brush border membrane is regulated in response to flow.

149 escence localized the P2Y(1) receptor to the brush border membrane of duodenal villi.

150 nriched in the small intestine and is in the brush border membrane of enterocytes.

151 by increasing NHE3 protein abundance at the brush border membrane of intestinal epithelial cells.

152 her show that native ABCG2 is located in the brush border membrane of kidney proximal tubule cells, w

153 tic lipid mixtures and lipid extracts of the brush border membrane of mouse kidney cells.

154 logue of human SLC26A6, was localized to the brush border membrane of proximal tubule cells and was d

155 ed the dynamic translocation of GLUT2 to the brush border membrane of RPTCs, and reduced glucose reab

156 rption is mediated by SGLT1 localized in the brush border membrane of small intestinal enterocytes, i

157 The intestinal brush border membrane of the canine hookworm, Ancylostom

158 immunohistochemistry localized SGLT2 to the brush border membrane of the early proximal tubule.

159 ctivity of a putative sterol permease in the brush border membrane of the enterocyte that actively fa

160 raluminal cholesterol molecules crossing the brush border membrane of the enterocyte.

161 ue, PgCad1 protein occurred primarily on the brush border membrane only in susceptible larvae.

162 ssays of Cry1Ac, Cry2Aa and Cry1Ca to midgut brush border membrane proteins from BPH and PWS.

163 of specific alkaline phosphatase activity in brush border membrane proteins from susceptible (YDK and

164 CaLP expressed in S2 cells or in solubilized brush border membrane proteins.

165 n assays with GST-fusion proteins and native brush border membrane proteins.

166 P(i) flux at the apical (luminal) brush border membrane represents the rate-limiting step

167 Indomethacin treatment increased renal brush border membrane vesicle NaPi-2 protein abundance i

168 g and oligomerization by western blots using brush border membrane vesicles (BBMV) from a strain of P

169 hibitory AgAPN2ta blocked Cry11Ba binding to brush border membrane vesicles (BBMV) of A. gambiae wher

170 kDa aminopeptidase N (APN) was isolated from brush border membrane vesicles (BBMV) of Anopheles quadr

171 ence of specific binding sites on the midgut brush border membrane vesicles (BBMV) of both insect spe

172 , and Cry8Ba on western corn rootworm midgut brush border membrane vesicles (BBMV).

173 Partial purification of proteins from brush border membrane vesicles (BBMVs) by gel filtration

174 ce the structure and stability of BT-R(1) on brush border membrane vesicles (BBMVs) prepared from M.

175 e and detected a 65 kDa species on a blot of brush border membrane vesicles (BBMVs) protein prepared

176 ertion of the whole toxin into Manduca sexta brush border membrane vesicles (BBMVs).

177 ibited phosphate transport in isolated renal brush border membrane vesicles and in cultured renal pro

178 unctional activity as Cl-oxalate exchange in brush border membrane vesicles and oxalate-stimulated vo

179 By contrast, phosphate transport in brush border membrane vesicles and proximal tubule cells

180 d the level of binding of [(125)I]Cry11Ba to brush border membrane vesicles by 41%, a percentage comp

181 bits sodium-dependent phosphate transport in brush border membrane vesicles derived from hormone-trea

182 ority of ASBT (~80%) was S-acylated in ileal brush border membrane vesicles from human organ donors,

183 protein that is present at reduced levels in brush border membrane vesicles from YHD2 larvae.

184 Brush border membrane vesicles prepared from rabbit kidn

185 Toxin-binding assays using brush border membrane vesicles revealed that a wild-type

186 CR12-MPED peptide bound brush border membrane vesicles with high affinity (K(d)

187 Finally, in assays with aphid gut-derived brush border membrane vesicles, binding of CP-P-GFP comp

188 membranes, including in Aedes aegypti larval brush border membrane vesicles, small unilamellar vesicl

189 levels of gamma-secretase activity in renal brush border membrane vesicles.

190 mately 2-3-fold in these rafts compared with brush border membrane vesicles.

191 significantly impaired intestinal epithelium brush border membrane, junctional polarity, and maturati

192 we have investigated the susceptibility and brush border membrane-binding properties of both species

193 ase of the GLUT2/SGLT-1 protein ratio in the brush border membrane.

194 sodium-phosphate cotransporter Npt2a at the brush border membrane.

195 reductions in NPT2a expression in the renal brush border membrane.

196 e fraction, of which 40-50% was localized to brush border membrane.

197 water transport across the human intestinal brush border membrane.

198 ytes form through invagination of the apical brush border membrane.

199 and protein levels of NHE3 and SGLT1 in the brush border membrane.

200 hanced AQP1 abundance in the proximal tubule brush border membrane.

201 ponsible for transport across the intestinal brush border membrane; however, the carrier(s) responsib

202 all intestinal glucose absorption across the brush-border membrane (BBM) via SGLT1 and GLUT2 were ana

203 -Reg variant that downregulates SGLT1 in the brush-border membrane at high luminal glucose concentrat

204 ERF1 is specifically localized at the apical brush-border membrane in intestinal epithelial cells and

205 Enrichment of PLBs with WCRW midgut brush-border membrane material resulted in a 2000-fold r

206 -glutamyl transpeptidase (GGT) on the apical brush-border membrane of 786-O proximal tubule cells wit

207 tein was iron regulated and localized to the brush-border membrane of duodenal enterocytes in iron de

208 f the visceral endoderm and localized to the brush-border membrane of extraembryonic endodermal cells

209 Taurine uptake across the brush-border membrane of human intestinal Caco-2 cell mo

210 mino acid transport function measured at the brush-border membrane of intact intestinal epithelia res

211 Ac-CP-2 is expressed by the parasite in the brush-border membrane of its alimentary canal, and anti-

212 l role in folate transport across the apical brush-border membrane of the proximal small intestine es

213 n by all gastric, pancreatic, and intestinal brush-border membrane proteases.

214 rric iron is attributed to the presence of a brush-border membrane reductase activity that displays a

215 nhibit Na+/glucose transport into intestinal brush-border membrane vesicles.

216 d activation and recruitment of GLUT2 to the brush-border membrane.

217 expressed on the apical domain of the ileal brush-border membrane.

218 nance of active ERM proteins at the cortical brush border membranes (BBM) of polarized epithelia.

219 Experiments using brush border membranes and cultured renal proximal tubul

220 expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain can

221 y 1,120 kDa that bound to solubilized insect brush border membranes and induced pore formation in bla

222 onide binds specifically to a single site in brush border membranes and to human embryonic kidney 293

223 t helices alpha-4 or alpha-6 insert into the brush border membranes because of their hydrophobic natu

224 the membrane proteinase meprin beta found in brush border membranes of kidney and small intestine.

225 RC and TfR1 mediate hTf uptake across apical brush border membranes of PTECs and reciprocally respond

226 s study, GUVs were assembled from rat kidney brush border membranes, which included the integral memb

227 ular, the insertion of the toxin into insect brush border membranes.

228 e, ERM proteins are significantly reduced in brush-border membranes from kidney and small intestine.

229 eduction in the transporter protein in renal brush-border membranes isolated from the mutant mice.

230 B (ANKS4B) localizes to the tips of adherent brush border microvilli and is essential for intermicrov

231 Brush border microvilli enable functions that are critic

232 For decades, enterocyte brush border microvilli have been viewed as passive cyto

233 zation resulting in the morphogenesis of the brush border microvilli in epithelial cells remain unkno

234 not absolutely required for the formation of brush border microvilli or for the establishment or main

235 ocadherin-based complex found at the tips of brush border microvilli that mediates adhesion between n

236 Rab25-knockdown cells showed disorganized brush border microvilli with decreases in villin express

237 Within brush border microvilli, Myo1a carries out a number of c

238 imately to intestinal enterocytes and efface brush border microvilli.

239 These data support our hypothesis that the "brush-border" microvilli serve a mechanosensory function

240 Brush-border mobility was determined by fluorescence rec

241 ates two distinct adhesive interactions with brush border molecules of the intestinal epithelial cell

242 To gain insight on how CDHR2 contributes to brush border morphogenesis and enterocyte function under

243 inal enterocytes did not identify defects in brush border morphology or structural polarization, demo

244 and careful examination of tissue, cell, and brush border morphology revealed several perturbations t

245 dherin mislocalization and severe defects in brush border morphology.

246 led that in the in vitro context of isolated brush borders, myosin-1a (myo1a) powers the sliding of m

247 In our studies of the intestinal brush border Na+-glucose cotransporter we have obtained

248 on due to TNF-induced internalization of the brush border Na+/H+ exchanger NHE3.

249 olutes, and water and the endocytosis of the brush border Na+/H+ exchanger, thereby inhibiting Na+ ab

250 The epithelial brush-border Na(+)/H(+) exchanger NHE3 is acutely inhibi

251 rter 3 (NHE3), which is the major intestinal brush-border Na(+)/H(+) exchanger.

252 It is associated with increased brush-border NHE3 and association between ezrin and NHE3

253 n actin bundling protein found in the apical brush border of absorptive tissues, is one of the first

254 brane projections that form the basis of the brush border of enterocytes and the Drosophila melanogas

255 lin is a major actin-bundling protein in the brush border of epithelial cells.

256 or actin-bundling protein that assembles the brush border of intestinal and renal epithelial cells.

257 occupies a unique intracellular niche at the brush border of intestinal epithelial cells, where it un

258 scaffold to membrane proteins in the apical brush border of intestinal epithelial cells.

259 rt-tailed class I motor, myosin-1c, into the brush border of knockout enterocytes.

260 um samples from the patient reacted with the brush border of normal human kidney, in contrast with th

261 expression of NHE3 was reduced in the ileal brush border of patients with diarrhea.

262 d gamma-secretase activity were found in the brush border of proximal kidney tubules where megalin is

263 b2 (p = 0.006) were significantly reduced in brush border of syncytiotrophoblast of infected placenta

264 e neonatal Fc receptor (FcRn) located at the brush border of the apical membrane has been implicated

265 , FcRn is expressed on the podocytes and the brush border of the proximal tubular epithelium.

266 CFEX are localized to and maintained in the brush border of the proximal tubule are largely unknown.

267 lar holo-Tf (hTf) acquisition, to the apical brush border of the PT, with expression gradually declin

268 ction to target a disaccharidase to rafts in brush borders of intestinal mammalian cells.

269 Villin 1, a protein typically found in the brush borders of proximal tubular cells, has been detect

270 zes mainly to the podocyte cell membrane and brush borders of the proximal tubule cells.

271 lar membrane morphology, distinct changes in brush-border organization, loss of numerous cytoskeletal

272 The susceptibility to the brush-border peptidases and route of transepithelial tra

273 croclimate overlying the duodenal enterocyte brush border protects the mucosa from luminal acid.

274 Here we demonstrate that the brush border protein Myosin Ia (MYO1A) is important for

275 and demonstrate that the loss of structural brush border proteins involved in cell polarity are impo

276 Second, FasG recognizes specific intestinal brush border proteins that migrate on a sodium-dodecyl s

277 In the enterocyte brush border, protocadherin function requires a complex

278 The intestinal brush border provides an elaborate example with tightly

279 idney tubules resulted in loss of the tubule brush border, reduced GFR, pericardial edema, and increa

280 aling pathways, are also concentrated in the brush border region of PTE and are present in megalin-ex

281 it, Galphai3, has also been localized to the brush border region of PTE.

282 thrin-coated pits (CCPs) and vesicles in the brush border region.

283 Brush-border sucrase-isomaltase (SI) activity is complem

284 y expressed in the small intestine along the brush border, suggesting that the neutral ceramidase may

285 ession of ACE2 on the small bowel enterocyte brush border supports intestinal infectivity by SARS-CoV

286 heir association with the negatively charged brush border surfaces.

287 Preliminary characterization of the brush border target antigen excluded megalin, CD10, and

288 i, but only lactaderin-C2 expression reduced brush border targeting of Myo1a-TH1.

289 The polarized enterocytes developed brush borders, tight junctions and desmosomes, and goble

290 his case, NHERF2 directly binds cGKII in the brush border to form an NHE3 complex, with cGKII also as

291 hat are characterized by an elaborate apical brush border to increase transport efficiency.

292 ls generate arrays of microvilli, known as a brush border, to enhance functional capacity.

293 ld-type mice had increased expression of the brush border transporter Dmt1.

294 at the brush border and although, as in the brush border, uptake is sodium independent, it is less s

295 e report here that ANKS4B is directed to the brush border using a noncanonical apical targeting seque

296 Brush border vesicle uptake of L-tryptophan is substanti

297 bacterial adherence assays by using porcine brush border vesicles that are specific to either the K8

298 gh concentration of actin residing in mature brush borders, we sought to determine whether enterocyte

299 ring tubule morphogenesis, localizing to the brush border whenever the tissue is transport competent.

300 nctions and positioned below the microvillar brush border, which suggests a protective intracellular

301 h-matched and assembled into tightly packed "brush borders," which are organized by ~50-nm thread-lik