ライフサイエンスコーパス: budding yeast

1 to achieve proper timing of cell division in budding yeast.

2 hase axis length and S-phase progression, in budding yeast.

3 me bi-orientation, independently of Bir1, in budding yeast.

4 ry dynamics at high resolution in laboratory budding yeast.

5 tion initiation in the compact genome of the budding yeast.

6 he NPC and the mobile transport machinery in budding yeast.

7 class of low-frequency stochastic origins in budding yeast.

8 c chaperone for the histone variant H2A.Z in budding yeast.

9 keleton, chromatin, and DNA damage repair in budding yeast.

10 he interplay of architecture and function in budding yeast.

11 oordinate a timely cell cycle progression in budding yeast.

12 ive dealkylation of alkylated nucleobases in budding yeast.

13 ibosomal DNA that comprises the nucleolus of budding yeast.

14 chor for endocytic actin assembly factors in budding yeast.

15 at links mitotic entry to membrane growth in budding yeast.

16 emerging coding sequences impact fitness in budding yeast.

17 and in enhancing promoter directionality in budding yeast.

18 sm for the emergence of copper resistance in budding yeast.

19 conformation and 3D nuclear organization in budding yeast.

20 e signal transduction and gene expression in budding yeast.

21 re immediate effect in the early anaphase of budding yeast.

22 at is called B55 in vertebrates and Cdc55 in budding yeast.

23 owth rate via the TORC2 signaling network in budding yeast.

24 larizes dynein-mediated spindle movements in budding yeast.

25 is play a major role in cell size control in budding yeast.

26 3' exoribonuclease, as a cofactor of RNAi in budding yeast.

27 tial to fulfil recombinational DNA repair in budding yeast.

28 g numerous pathways that lack equivalents in budding yeast.

29 one of the two major osmosensing pathways in budding yeast.

30 two splicing isoforms of the same protein in budding yeast.

31 lance of defective nuclear pore complexes in budding yeast.

32 location and role in global transcription in budding yeast.

33 determinant of cell size in bacteria and in budding yeast.

34 CAT-tailing in nascent-chain degradation in budding yeast.

35 ding intermediates prior to DNA insertion in budding yeast.

36 or the asymmetric cell shape and division of budding yeast.

37 s the centromeric base of the kinetochore in budding yeast.

38 at centromeric (CEN) chromatin in wild-type budding yeast.

39 biquitin chain required for damage bypass in budding yeast.

40 litates MutLgamma-dependent crossing over in budding yeast.

41 ents suggest that bet hedging has evolved in budding yeast.

42 e first cell division cycle (CDC) mutants in budding yeast.

43 unction for MRX in limiting transcription in budding yeast.

44 p40, an essential RNA-splicing factor in the budding yeast.

45 nfluences both of these replication steps in budding yeast.

46 is orchestrated by the Atg1-Atg13 complex in budding yeast.

47 nuclear parasites that have co-evolved with budding yeasts.

48 e split of Yarrowia lipolytica and the other budding yeasts.

49 gene expression output, we have conducted in budding yeast a large-scale measurement of the activity

50 In budding yeast, a conserved signaling network surrounding

51 In budding yeast, a specific growth site is selected in the

52 rated analogous R402C and R402H mutations in budding yeast alpha-tubulin, which exhibit a simplified

53 We investigated these questions in budding yeast, an organism found in diverse environments

54 chanism for dosage compensation in aneuploid budding yeast and human cell lines.

55 tro, but different results were obtained for budding yeast and human SAD kinases.

56 Both budding yeast and human tumor cells utilize members of a

57 g kinases, delineating the key substrates in budding yeast and humans.

58 In contrast, herein we analyze Hi-C data for budding yeast and identify 200-kb scale TADs, whose boun

59 ncreased genomic instability during aging in budding yeast and identify striking age-associated genom

60 ily of endocytic adaptors, including Syp1 in budding yeast and its mammalian orthologue, FCHo1.

61 e modeled pathogenic EXOSC5 variants in both budding yeast and mammalian cells.

62 and exchange during meiotic recombination in budding yeast and many other organisms including humans.

63 ible DNA at almost all genomic AluI sites in budding yeast and mouse liver nuclei.

64 iBi regulation as cells initiated meiosis in budding yeast and noted early transcriptional activation

65 Here we show that growing budding yeast and primary mammalian cells beyond a certa

66 tional signature of redox stress in ssDNA of budding yeast and the signature of aging in human mitoch

67 in and regulate force, we purified SPBs from budding yeast and used laser trapping to manipulate sing

68 to show that autoinhibition is conserved in budding yeast, and plays a key role in coordinating in v

69 dissolution and reformation cycle exists in budding yeast, and the precise course of nucleolar segre

70 These fungi include a mold, a budding yeast, and thermal dimorphic fungi.

71 its inhibitor Sic1 at the G1/S checkpoint in budding yeast, APC:Cdc20 and its inhibitor MCC at the mi

72 icrotubules, the simple point centromeres of budding yeast are connected to individual microtubules(5

73 e role of mitochondria in this process using budding yeast as a model.

74 h dynein studies in human cells, we employed budding yeast as a screening platform to characterize th

75 The interaction pattern of budding yeast as measured from genome-wide 3C studies ar

76 h defined positions throughout the genome of budding yeast, as seen in mammalian cells.

77 Using the budding yeast Ase1, we identify unique contributions for

78 the oscillations of the anaphase spindle in budding yeast, but in A. gossypii, this system is not re

79 s in Saccharomyces cerevisiae and some other budding yeasts, but most eukaryotes lack sequence-specif

80 pr) inserted into the silenced chromosome in budding yeast can overcome Sir2-dependent silencing upon

81 Budding yeast can produce ATP from carbon sources by mec

82 variation to uncover a novel means by which budding yeasts can overcome highly successful genetic pa

83 In budding yeast, CDK substrates with Leu/Pro-rich (LP) doc

84 a gradient in tension over multiple isogenic budding yeast cell lines by genetically altering the mag

85 In budding yeast, cell cycle progression and ribosome bioge

86 In budding yeast, cell size is thought to be controlled alm

87 In budding yeast, cell size primarily modulates the duratio

88 EMBO Journal, Stahl et al (2019) reveal that budding yeast cells confer a growth advantage to their d

89 r to produce rejuvenated daughters, dividing budding yeast cells confine aging factors, including pro

90 increased cell death caused by DNA damage in budding yeast cells lacking the Rad53 checkpoint protein

91 We conclude that aneuploid budding yeast cells mount the ESR, rather than the CAGE

92 e fluorescence microscopy techniques in live budding yeast cells to investigate how Mex67 facilitates

93 The gene that allows budding yeast cells to switch their mating type evolved

94 in have shown that in response to pheromone, budding yeast cells undergo a rise of cytosolic Ca(2+) t

95 properties of formaldehyde-cross-linking in budding yeast cells.

96 One such locus is the budding yeast centromere, which is a paradigm for target

97 In budding yeast, centromere establishment begins with the

98 Budding yeast centromeres comprise three sequential "cen

99 In budding yeast, centromeres are flanked by replication or

100 All 16 budding yeast chromosomes assemble complete kinetochores

101 to argue that the small, highly constrained budding yeast chromosomes could not have these structure

102 Recent breakthroughs with synthetic budding yeast chromosomes expedite the creation of synth

103 a two-dimensional agent-based model to study budding yeast colonies with cell-type specific biologica

104 Purification of budding yeast condensin reveals that it occurs not only

105 In budding yeast, cortical and cytoplasmic ER-phagy require

106 report the finding of a new function for the budding yeast Cse4/CENP-A histone-fold domain interactin

107 In budding yeast, cytokinetic actomyosin ring contraction a

108 In particular, budding yeast daughter cells are more vulnerable to stre

109 Mammals, unlike budding yeast, depend on the histone H3 variant, CENP-A,

110 The mating of budding yeast depends on chemotropism, a fundamental cel

111 hesin loader, whose presence on chromatin in budding yeast depends on the RSC chromatin remodeling co

112 The localization of Ipl1 to kinetochores in budding yeast depends upon multiple pathways, including

113 This mutant, when expressed in budding yeast, diminished cell growth and DNA replicatio

114 ior requires the microtubule regulator Stu2 (budding yeast Dis1/XMAP215 ortholog), which we demonstra

115 Budding yeast divide asymmetrically and HO is expressed

116 Using the reconstituted budding yeast DNA replication system, we find that the f

117 Our findings indicate that size control in budding yeast does not fundamentally originate from the

118 The spindle pole body (SPB) of budding yeast duplicates once per cell cycle.

119 In budding yeast, dynein moves the mitotic spindle to the p

120 In budding yeast, each chromosome has a point centromere up

121 In budding yeast, end processing requires the helicase Sgs1

122 In this work, we show that budding yeast executes meiotically programmed mitochondr

123 nal modeling of the full genome during G1 in budding yeast, exploring four decades of timescales for

124 c cells because most prior studies have used budding yeast for RLS studies.

125 A newly characterized group of budding yeast found in fermented milk drinks in West and

126 ere are two distinct TRAPP complexes, yet in budding yeast, four distinct TRAPP complexes have been r

127 Budding yeast Fun30 and human SMARCAD1 are cell cycle-re

128 To examine whether budding yeast function at this limit of full ribosomal u

129 ether the main histone acetyltransferases in budding yeast, Gcn5 and Esa1, possess crotonyltransferas

130 model (mC-SAC) to gain understanding of the budding yeast genome organization.

131 N-linked glycosylation of proteins in budding yeast has been assumed to be a cotranslational r

132 d two different strategies for size control: budding yeast has been proposed to use an inhibitor-dilu

133 In budding yeast, histone H3 threonine 11 phosphorylation (

134 Here, we have reconstituted budding yeast Hsf1-Hsp70 activation complexes and find t

135 Here, we find that involvement of the budding yeast Hsp70 chaperones Ssa1 and Ssa2 in nuclear

136 Here we study budding yeast in dynamic environments of hyperosmotic st

137 Compared to other budding yeasts in the subphylum Saccharomycotina, we not

138 series of transcriptome sequencing data from budding yeast, in high temporal resolution over ca. 2.5

139 We addressed this question in budding yeast, in which cells enter meiosis when starved

140 on in vitro using six purified proteins from budding yeast including Dmc1 and its accessory proteins

141 our assay robustly detects small changes in budding yeast initiation kinetics, which could not be re

142 mitochondrial carrier family protein Pic2 in budding yeast is a copper importer.

143 lucose-mediated repression of respiration in budding yeast is at least partly due to the low cellular

144 nto the first gap phase of the cell cycle in budding yeast is controlled by the Mitotic Exit Network

145 One step in this assembly in budding yeast is the association of Cdc45 with the Mcm2-

146 Cell type in budding yeasts is determined by the genotype at the mati

147 to other eukaryotes with symmetric division, budding yeast keeps the nascent transcription rates of i

148 Here, we show that key functions of budding yeast Kinesin-14 Cik1-Kar3 are accomplished in a

149 d here the forces that ensembles of purified budding yeast kinesin-5 Cin8 produce in microtubule glid

150 iscussion, we will use the relatively simple budding yeast kinetochore as a model, and extrapolate in

151 crosslink-guided in vitro reconstitution of budding yeast kinetochore complexes we showed that the A

152 We discovered that in budding yeast, kinetochore inactivation occurs by reduci

153 anisms of group formation in the unicellular budding yeast Kluyveromyces lactis.

154 is study, we find that Stu1 recruits Stu2 to budding yeast KTs, which promotes MT generation there.

155 Msp1 is a conserved AAA ATPase in budding yeast localized to mitochondria where it prevent

156 In budding yeast meiosis, homologous chromosomes become lin

157 ored the potential for autophagy to regulate budding yeast meiosis.

158 In budding yeast, meiotic kinetochore remodeling is mediate

159 Here we show that the budding yeast mismatch repair related MutLbeta complex,

160 In budding yeast, mitochondria drive the assembly of the mi

161 tial partitioning of nucleolar components in budding yeast mitosis.

162 examine the DDC, induced by DNA DSBs, in the budding yeast model system and in mammals.

163 Using a budding yeast model, we show that the ESCRT Chm7 and the

164 Here, we uncover a mechanism by which budding yeast modulate viscosity in response to temperat

165 Fission yeast Mso1 shares homology with budding yeast Mso1 and human Mint1, proteins that intera

166 ears ago, the first isolation of conditional budding yeast mutants that were defective in cell divisi

167 tly image and quantitate these dynamics in a budding yeast nuclear extract that reconstitutes activat

168 Fluorescent labeling of budding yeast nucleoli with CDC14-GFP revealed that a sp

169 he consequences to the size and shape of the budding yeast nucleus when cell expansion is inhibited b

170 work defines spatial organization within the budding yeast nucleus, demonstrates the conserved role o

171 Here we show the existence in budding yeast of a common aneuploidy gene-expression sig

172 Here, we show that Mph1, the budding yeast ortholog of Fanconi anemia helicase FANCM,

173 To identify other factors that act in the budding-yeast pathway, we performed an unbiased genetic

174 Boi1 and Boi2 (Boi1/2) are budding yeast plasma membrane proteins that function in

175 conserved motif that echoes the structure of budding yeast point centromeres.

176 In budding yeast, polarization is associated with a focus o

177 The budding yeast Polo-like kinase Cdc5 is a key regulator o

178 fission yeast or a single ring of NPFs as in budding yeast produce enough force to elongate the invag

179 Single-molecule analysis with purified budding yeast proteins shows that Rad52 competes with Sg

180 reconstituting these processes with purified budding yeast proteins, we show that ubiquitylation is t

181 is essential, we previously interrogated the budding yeast proteome to identify candidates that funct

182 ith our in vitro results, our experiments in budding yeast provide evidence that Rad52 inverse strand

183 Although budding yeast Rad51 has been extensively characterized i

184 Budding yeast Rad52 similarly inhibits Sgs1-dependent re

185 The Mitotic Exit Network (MEN), a budding yeast Ras-like signal transduction cascade, tran

186 Here, we show that 'axis core proteins' from budding yeast (Red1), mammals (SYCP2/SYCP3), and plants

187 cative DNA helicase, CMG, demonstrating that budding yeast replisomes lack intrinsic mechanisms that

188 Using reconstituted budding yeast replisomes, we show that mutational inacti

189 Clathrin-mediated endocytosis in budding yeast requires the formation of a dynamic actin

190 Here we show that Y1F substitution in budding yeast resulted in a strong slow-growth phenotype

191 Modeling the dysregulation in budding yeast resulted in disrupted structural integrity

192 In budding yeast, Rph1 transcriptionally represses many DNA

193 protein that is structurally related to the budding yeast Rtt107 and human PTIP DNA damage response

194 CCS1, the budding yeast (S. cerevisiae) Cu chaperone for Cu-zinc (

195 start sites (TSSs) has been identified in a budding yeast Saccharomyces cerevisiae ("scanning model"

196 utational effects for gene expression in the budding yeast Saccharomyces cerevisiae by measuring the

197 The budding yeast Saccharomyces cerevisiae divides asymmetri

198 ry mechanisms in model organisms such as the budding yeast Saccharomyces cerevisiae Gpa2 is a yeast G

199 Genetic screening in the budding yeast Saccharomyces cerevisiae has isolated seve

200 Features of this regulatory circuit in the budding yeast Saccharomyces cerevisiae have been recentl

201 The budding yeast Saccharomyces cerevisiae is a long-standin

202 Under aerobic conditions, the budding yeast Saccharomyces cerevisiae metabolizes gluco

203 c view of the eukaryal cell cycle, using the budding yeast Saccharomyces cerevisiae Protein synthesis

204 The budding yeast Saccharomyces cerevisiae stores iron in th

205 alyzed separation of function mutants in the budding yeast Saccharomyces cerevisiae that allow global

206 of nuclear microtubule (MT) dynamics in the budding yeast Saccharomyces cerevisiae This activity req

207 -wide fluorescence microscopy studies in the budding yeast Saccharomyces cerevisiae to identify a pro

208 ow that arrest of ribosome biogenesis in the budding yeast Saccharomyces cerevisiae triggers rapid ac

209 genetic instability in diploid cells of the budding yeast Saccharomyces cerevisiae, and have isolate

210 In the budding yeast Saccharomyces cerevisiae, ECM remodeling r

211 analyses, we show that DDR activation in the budding yeast Saccharomyces cerevisiae, either by geneti

212 In the budding yeast Saccharomyces cerevisiae, nearly all H2A i

213 In the budding yeast Saccharomyces cerevisiae, the five mitotic

214 In budding yeast Saccharomyces cerevisiae, the ten-subunit

215 In the budding yeast Saccharomyces cerevisiae, we demonstrate t

216 Here, using the budding yeast Saccharomyces cerevisiae, we report the di

217 on in G1/S transcriptional regulation in the budding yeast Saccharomyces cerevisiae.

218 d53 to distinct replication complexes in the budding yeast Saccharomyces cerevisiae.

219 sm on the variabilities in cell cycle of the budding yeast Saccharomyces cerevisiae.

220 sites of presumed protein aggregation in the budding yeast Saccharomyces cerevisiae.

221 ession and stability of certain mRNAs in the budding yeast Saccharomyces cerevisiae.

222 ys a central role in zinc homeostasis in the budding yeast Saccharomyces cerevisiae.

223 P protein that is homologous to Glo3p of the budding yeast Saccharomyces cerevisiae.

224 -driven reaction cycle of condensin from the budding yeast Saccharomyces cerevisiae.

225 tructed by cloning the centromere DNA of the budding yeast Saccharomyces cerevisiae.

226 -dimensional structure of pericentromeres in budding yeast (Saccharomyces cerevisiae) and establish t

227 n TMEM165 by heterologously expressing it in budding yeast (Saccharomyces cerevisiae) and in the bact

228 The lysosomal vacuole of budding yeast (Saccharomyces cerevisiae) has served as a

229 The Mag1 and Tpa1 proteins from budding yeast (Saccharomyces cerevisiae) have both been

230 active subunit Rrp44/Dis3 of the exosome in budding yeast (Saccharomyces cerevisiae) is considered a

231 The yeast vacuolar H(+)-ATPase (V-ATPase) of budding yeast (Saccharomyces cerevisiae) is regulated by

232 gated the selectivity and sensitivity of the budding yeast (Saccharomyces cerevisiae) multidrug respo

233 Budding yeast (Saccharomyces cerevisiae) responds to low

234 Here, we used budding yeast (Saccharomyces cerevisiae) to explore how

235 In budding yeast (Saccharomyces cerevisiae), EVs function a

236 K-PPn was originally discovered in budding yeast (Saccharomyces cerevisiae), in which polyP

237 of pantothenic acid for CoA biosynthesis in budding yeast (Saccharomyces cerevisiae), significantly

238 In budding yeast (Saccharomyces cerevisiae), the essential

239 Here, using budding yeast (Saccharomyces cerevisiae), we established

240 otein complex replication protein A (RPA) in budding yeast (Saccharomyces cerevisiae).

241 oduced dUTP/5-FdUTP-mediated DNA toxicity in budding yeast (Saccharomyces cerevisiae).

242 tages, we developed a method for scRNAseq in budding yeast (Saccharomyces cerevisiae).

243 he small pseudosubstrate inhibitor Acm1 from budding yeast (Saccharomyces cerevisiae).

244 In budding yeast, Saccharomyces cerevisiae, CR is commonly

245 The budding yeast, Saccharomyces cerevisiae, harbors several

246 We used the budding yeast, Saccharomyces cerevisiae, to investigate

247 We forced the budding yeast, Saccharomyces cerevisiae, to use the meio

248 Fission yeast Ctp1 and its budding yeast (Sae2) and human (CtIP) homologs control M

249 The budding yeast SCF(Met30) complex is an essential cullin-

250 g the hourglass-to-double-ring transition in budding yeast, septins acquire a "zonal architecture" in

251 Budding yeast SER3 is repressed under serine-replete con

252 that a Rad51 paralog-containing complex, the budding yeast Shu complex, directly recognizes and enabl

253 revisiae had a single evolutionary origin in budding yeasts, simpler "flip/flop" mechanisms of switch

254 This domain also exhibits homology with budding yeast Sld7.

255 Here we purified the budding yeast Smc5/6 holocomplex and characterized its c

256 CC), assembles into a hexameric array at the budding yeast SPB core, where it functions as a scaffold

257 unctional similarities between Ppc89 and the budding yeast SPB scaffold Spc42, distribution of Sad1 t

258 rred the mating compatibility systems of 332 budding yeast species from their genome sequences.

259 n (iHyPr) to combine the genomes of multiple budding yeast species, generating Saccharomyces allopoly

260 romyces cerevisiae, RNAi is present in other budding-yeast species, including Naumovozyma castellii,

261 f multiple kinases by the meiosis-I-specific budding yeast Spo13 protein.

262 elatives of Escherichia coli into a group of budding yeast taxa.

263 A strain of budding yeast that contains one large chromosome reveals

264 In budding yeast, the 3' end processing of mRNA and the cou

265 he environment drive cell fate decisions. In budding yeast, the decision to enter meiosis is controll

266 In budding yeast, the myosin-V Myo2 is aided by the kinesin

267 In budding yeast, the nuclear RNA surveillance system is ac

268 In budding yeast, the protein Gps1 plays a pivotal role in

269 In budding yeast, the retention of kinetochores on dynamic

270 Prior to anaphase of budding yeast, the ribosomal DNA (RDN) condenses to a th

271 In budding yeast, the transcription factors SBF and MBF act

272 Here, using proteomics-based approaches in budding yeast to analyze the effects of Nop53 on the exo

273 Using budding yeast to gain temporal and genetic traction on c

274 dics to investigate the adaptive response of budding yeast to temporally controlled H2O2 stress patte

275 In budding yeast, transcription within 20 kb of telomeres i

276 Budding yeast treated with hydroxyurea (HU) activate the

277 tubules assembled in vitro from mammalian or budding yeast tubulin.

278 In aneuploid budding yeast, two opposing gene-expression patterns hav

279 We show that budding yeast Ty3/Gypsy co-opts binding sites of the ess

280 Here we show that in budding yeast, under nutrient limiting conditions, the c

281 and the scope of RNA-based regulation in the budding yeast UPR and have implications for the control

282 During the budding yeast UPR, Ire1 excises an intron from the HAC1

283 The budding yeast v-SNARE, Snc1, mediates fusion of exocytic

284 In contrast to budding yeast, WASp-mediated actin nucleation plays an e

285 Using budding yeast, we demonstrate that global genotoxic dama

286 , bead-spring representation of chromatin in budding yeast, we find enrichment of protein-mediated, d

287 Using time-lapse fluorescence microscopy in budding yeast, we found that nuclear senescence factors

288 ion of two plant AMTs (AtAMT1;2 and AMT2) in budding yeast, we found that systematic replacements in

289 Here, using budding yeast, we identify a proteolytic pathway that co

290 To overcome these hurdles for budding yeast, we recently optimized an artificial fluor

291 Performing experiments in budding yeast, we show that our estimates of numbers agr

292 l dynamics during meiotic differentiation in budding yeast, we sought to understand how organelle mor

293 tion systems by using extracts prepared from budding yeast, wheat germ, and rabbit reticulocyte lysat

294 focus on recent systematic studies, many in budding yeast, which have revealed that large numbers of

295 Here we use budding yeast, which lack Torsins, to interrogate TorA f

296 In budding yeast, which possesses simple point centromeres,

297 Budding yeast, which undergoes polarized growth during b

298 In budding yeast, while most of the genome segregates at th

299 rom IMR90 (human lung fibroblast), and (iii) budding yeast whole-genome Hi-C data at a single restric

300 nced toolbox of cell cycle tag constructs in budding yeast with defined and compatible peak expressio