ライフサイエンスコーパス: buildup

1 is protection itself is vulnerable to AbetaO buildup.

2 ather than respond to, the initial cytokinin buildup.

3 l mechanisms to mitigate cytoplasmic ammonia buildup.

4 that can detect and localize microstructure buildup.

5 component reflecting the behavioral decision buildup.

6 d and investigated to alleviate the salinity buildup.

7 ty acid propionic acid, preventing its toxic buildup.

8 tin sliding caused by prepower-stroke myosin buildup.

9 at monocyte infiltration dictates macrophage buildup.

10 to airway infection, inflammation, and mucus buildup.

11 ate staining characteristic of autophagosome buildup.

12 ssion of a phosphodiesterase to prevent cGMP buildup.

13 reaming either during alternations or during buildup.

14 formation, suggesting enhanced supercoiling buildup.

15 static lesions and progressive ascitic fluid buildup.

16 d on mode analysis and time-dependent lasing buildup.

17 ties forming lithified discrete stromatolite buildups.

18 phologies underneath bio-concretionned rocky buildups.

19 nstream (71%), as was extensive fibrin(ogen) buildup (87%).

20 The analysis of the buildup allows us to compare quantum mechanics and the c

21 ed likely related AEs during OIT (72% during buildup and 47% during maintenance).

22 ctic acidosis-the combination of lactate ion buildup and acidic pH-can increase the heterogeneity of

23 ry ammonium methacrylates to suppress plaque buildup and bacterial acid production.

24 mer-caused heterogeneities and governs force buildup and cell motility.

25 hibitory rebound burst caused by the regular buildup and decay of the availability of ITrans-LTS.

26 Here, we study damage buildup and defect interaction dynamics in 3C-SiC bombar

27 tly asymmetrical-indicative of prolonged ice buildup and delayed, but rapid, glacial terminations.

28 emarkable accuracy the spinal cord aggregate buildup and disease progression in transgenic mice.

29 t of residual coronal tissues after abutment buildup and final preparation: A) >50% of coronal residu

30 on episodes, starting with a period of PM2.5 buildup and followed by a period with plateauing concent

31 uced by LPS, C6(-/-) mice showed reduced PMN buildup and less lung epithelial/endothelial cell dysfun

32 nner that depends on the source of porphyrin buildup and light exposure.

33 ntermediate to Cl-, thereby preventing ClOx- buildup and lowering Re complex decomposition in the Re(

34 radiation) challenges assumptions about the buildup and maintenance of species in evolutionary radia

35 tion that mitotic arrest is required for ROS buildup and oxidation of the nucleotide pool.

36 overexpression greatly diminished SNO-GAPDH buildup and protected heme insertion from NO inhibition.

37 ed Ca(2+) extrusion may prevent toxic Ca(2+) buildup and provides an explanation for the stationary n

38 l feedback mechanism that contributes to the buildup and redirection of glycolytic intermediates to a

39 intensity and strength as well as realistic buildup and shutdown of wind burst activity in the weste

40 between the intensity of the subsurface heat buildup and the magnitude and timing of subsequent EN ep

41 We provide a detailed description on the buildup and the role of the different components in the

42 The residual buildup and treatment of dissolved contaminants in low p

43 tic model was developed to predict pesticide buildup and washoff processes on concrete surfaces.

44 and Fick's second law to describe pesticide buildup and washoff processes, respectively.

45 nes, macromolecules, and organelles, and its buildup appears to be vital for function.

46 ncies reveal that the dynamics of the allene buildup are controlled by the structural changes, wherea

47 the common agricultural dilemma of pathogen buildup associated with continuous cropping for this nat

48 The inhibitor mimics the hypothesized charge buildup at C-4 of chorismate in the TS as well as C-O bo

49 ors suggest hindrance to escape supercoiling buildup at low temperatures.

50 oncentrations behaved according to a barrier buildup at the membrane-solution interface by unsettled

51 monstrate that the dynamic aspects of damage buildup, attributed to defect trapping-detrapping proces

52 ovide sufficient air exchange to prevent CO2 buildup, but in-cabin UFP concentrations would increase.

53 carboxylic acid (TCA) cycle leads to acetate buildup by Ald4p.

54 uality control, leading to misfolded protein buildup, causing ER stress.

55 giving effective values for the exponential buildup constant gammaSEOP of 62.5 +/- 3.7 x 10(-3) min(

56 sent (5 kyBP), the concurrent C sink by peat buildup could mask large early LUC emissions.

57 PVEC results indicate that the beta-amyloid buildup curve does not plateau at an early symptomatic d

58 was hypothesized that the brain beta-amyloid buildup curve plateaus at an early symptomatic stage of

59 ntration and observing the effect on the STD buildup curve.

60 These buildup curves allow the confirmation of binding through

61 imensional REAPDOR and ZF-TEDOR experimental buildup curves and determined to be within 15% of previo

62 ng 1D selective exchange spectroscopy (EXSY) buildup curves and initial rate approximation.

63 NP leads to single-scan detection of the NOE buildup, despite that this signal peaks at only 2% of th

64 a rho(+) of -1.7, suggesting cationic charge buildup during the cyclization and supporting rate-deter

65 od of 15 minutes was biphasic, with response buildup during the first 6 to 7 minutes, followed by a s

66 kled, and bundled as well as undergo tension buildup during the structural reorganization.

67 size of estimated 50-112MDa and its complex buildup from about 500-1000 individual proteins, it is a

68 om near-zero to a steady value, defining the buildup function, BUF.

69 rved as nucleus for subsequent coralligenous buildups growth.

70 cting with a cavity - such as resonant field buildup - have remained confined to narrow linewidths.

71 lain DO events, including sea ice, ice shelf buildup, ice sheets, atmospheric circulation, and meltwa

72 The first significant buildup in atmospheric oxygen, the Great Oxidation Event

73 s after OVA challenge followed by eosinophil buildup in both compartments and a shift in phenotype ov

74 ions and show that regions of amyloid plaque buildup in brain tissue of Alzheimer's patients are acco

75 nded conformations, which may prevent torque buildup in chromatin during active transcription or repl

76 olonged and associated with significant mass buildup in early-Universe proto-clusters, and that many

77 ion therapies can not completely avoid dose buildup in front of the tumor volume.

78 ity of storage sites, and potential pressure buildup in storage reservoirs.

79 -accumulation and phytotoxic catabolite over-buildup in the chlorophyll degradation pathway.

80 h the solution reaction and stabilize charge buildup in the transition state.

81 symbiotic organs, consistent with enzymatic buildup in these structures following immunostaining wit

82 is found growing between (and on) microbial buildups in Namibia.

83 lysosomal disruption and autophagic vesicle buildup inside the myofiber due to a lack of obvious hep

84 Biofilms buildup internal mechanical stress as single cells grow

85 this perception in that the vascular plaque buildup is mainly caused by oxidized LDL (ox-LDL) rather

86 t the rate of escaping positive supercoiling buildup is temperature and transcription rate dependent.

87 The time course of [H(+)] buildup limits the speed of this intercellular signaling

88 t detection and disruption of cardiac amylin buildup may be both a predictor of heart dysfunction and

89 l increment-forming crustose coralline algal buildups now provides the first high-resolution in situ

90 nsitivity of EN to the magnitude of the heat buildup occurring in the ocean subsurface 21 months in a

91 el for the genesis of Holocene coralligenous buildups occurring in the northwestern Adriatic Sea offs

92 s cell (DSPEC) configuration resulted in the buildup of -Ru(III)P(3+), -Ru(III)OH(2+), and -Ru(IV) ho

93 of protons from hair cells and a subsequent buildup of [H(+)] within the confined chalice-shaped syn

94 ccumulation of oxidizing equivalents without buildup of a charge.

95 own of the rate-equation model, indicating a buildup of a highly correlated regime of the photocarrie

96 ific late TGN secretory pathway resulting in buildup of a key protein important for fungal developmen

97 centration of valinomycin (10 nM) to prevent buildup of a membrane potential without artificially inc

98 tation of the previous task might impede the buildup of a neural task representation.

99 n of atmospheric pCO2 that enabled the rapid buildup of a permanent ice sheet on the Antarctic contin

100 tethered-imine, or aryl iodide can allow the buildup of a range of pyrrole derivatives, where any of

101 fic fully symmetric optical modes during the buildup of a three-dimensional (3D) metallic state that

102 a phenomenon that can be exacerbated by the buildup of Abeta in the brain parenchyma.

103 clearance of protein products resulting in a buildup of abnormal proteins, including beta-amyloid and

104 under physiological conditions, preventing a buildup of acetaldehyde.

105 example of such an adaptive response is the buildup of acquired neuroprotection, a synaptic activity

106 d in a semantic schema was associated with a buildup of activity in the angular gyrus (AG) that predi

107 amidal cells triggers a gradual, exponential buildup of activity in the recurrent CA3 network.

108 Our results suggest that a buildup of actomyosin-dependent cortical tension and int

109 than when it was not, indicating diminished buildup of adaptation during stimulus-rivalry suppressio

110 Restricting the spatial buildup of amplification enhances frequency selectivity

111 attenuation of neural activity prevents the buildup of amyloid plaques and associated neural patholo

112 lipid diffusion, possibly by preventing the buildup of an actin-based cytocortex and by preventing m

113 otably cytochrome P450, with PN leads to the buildup of an intermediate species with a Soret band at

114 s that hamper patient treatment, such as the buildup of antibiotic resistances or low drug selectivit

115 esh, and rice yield is diminished due to the buildup of arsenic (As) in soil from irrigation with hig

116 Although the time-dependent buildup of asymmetric Fano line shapes in absorption spe

117 affect disease progression by modulating the buildup of beta-amyloid (Abeta) or releasing proinflamma

118 y dysregulated in iF2KO mice, leading to the buildup of bile acids within enterocytes.

119 n jaundice, a yellowing of the skin due to a buildup of bilirubin.

120 the homocoupling of aryl-alkynes affords the buildup of bisacetylene derivatives directly at surfaces

121 patients and Abca4(-/-) (STGD1) mice exhibit buildup of bisretinoid-containing lipofuscin pigments in

122 This leads to buildup of branched-chain keto-acids (BCKA) and branched

123 During snowmelt, buildup of BTs in roadside snowpiles and preferential pa

124 eat the operation numerous times without the buildup of byproducts.

125 ncreased levels of thiol metabolites and the buildup of cellular reduction potential.

126 erves organelle function, prevents the toxic buildup of cellular waste products, and provides substra

127 robic oxidation of methane, resulting in the buildup of CH4, formation of degassing cracks in sedimen

128 These processes involve the buildup of charge across the cell membrane, with subsequ

129 equivalents, because it exemplifies how the buildup of charge can be avoided yet light energy can be

130 the ability of the phlorin to stabilize the buildup of charge.

131 ecifically, previous studies have observed a buildup of choice-selective activity in motor regions ov

132 doplasmic reticulum enzyme that prevents the buildup of cholesterol in membranes by converting it to

133 view, atherosclerosis results from a passive buildup of cholesterol in the artery wall.

134 ing cyclohepta[b]furan core and also for the buildup of complex molecular architectures through highe

135 s robustness is due to the prevention of the buildup of correlations in the learned connectivity.

136 h Cu excretion sites, resulting in the toxic buildup of Cu in the liver of WD patients.

137 ode haem biosynthetic enzymes with resultant buildup of cytotoxic metabolic porphyrin intermediates.

138 olism (CsCYP707A, an ABA 8'-hydroxylase) and buildup of dehydrophaseic acid (DPA).

139 n), have been investigated as models for the buildup of dielectric properties, differentiating the ro

140 the Influenza A full length M2 protein, the buildup of dipolar-dephased (15)N signals from the tetra

141 isrupting the junction's fold eliminates the buildup of disease-related sfRNAs in human cells infecte

142 , dependent on tumor cell-autonomous gradual buildup of DNA double-strand break (DSB) misrepair.

143 The results argue that the buildup of ECA-lipid II sequesters part of the pool of U

144 in diabetic nephropathy (DN) by uncontrolled buildup of ECM, especially type IV collagen, which progr

145 ut also significantly reduce the risk of the buildup of ecotoxic forms of Se by promoting the biologi

146 This in turn leads to the buildup of electric charge in donor and acceptor domains

147 insically doped lattices, thus revealing the buildup of electric fields.

148 cific drug target activity was linked to the buildup of energy metabolites that feed the electron tra

149 itons, carriers and phonons, where a delayed buildup of excitons under on- and off-resonant pumping c

150 Buildup of fluoride, shorter-chain perfluorinated produc

151 tured intermediate occur without appreciable buildup of folded monomer.

152 partial loss of its GTPase activity and in a buildup of fragmented and dysfunctional mitochondria in

153 class flare events; (ii) systematic preflare buildup of free energy in the form of electric currents,

154 Gene flow counteracts the buildup of genome-wide differentiation, which is a hallm

155 A3B expression in UNG-null cells causes a buildup of genomic uracil, and the ensuing lethality req

156 sm and away from glycolysis, alleviating the buildup of glycolytic intermediates.

157 rms for addressing growing concerns over the buildup of greenhouse gas.

158 do and offset some of the warming due to the buildup of greenhouse gases in Earth's atmosphere.

159 bution study in a rat GBM model demonstrated buildup of high CGT level in tumors subjected to CGT-NP+

160 Due to this buildup of HOCs in the sediment, the highest water conce

161 on blocked membrane recycling and caused the buildup of huge membrane-connected cisternae, in contras

162 Buildup of hydrogen sulfide (H2S), which functions as a

163 Similar to cytochromes P450, the buildup of I435 occurs in nitric oxide synthases (NOSs)

164 xify/activate PN, although they all show the buildup of I435.

165 continuous cycle of arms races, causing the buildup of IASC, alternated by phases of IASC resolution

166 Each buildup of IMI enables the LG neuron to generate a self-

167 epilepsy characterized by the intracellular buildup of insoluble, hyperphosphorylated glycogen-like

168 nd show that cell proliferation prevents the buildup of intercellular forces within cell colonies, en

169 pression blocks this process, resulting in a buildup of intermediate progenitors (IPs) expressing pro

170 enated pentachlorobenzene to MCB with little buildup of intermediates.

171 Homozygous deletion of GDE1 results in a buildup of internal GroPCho that is restored to wild typ

172 in on the ground-state structure result in a buildup of internal stress not exceeding 0.5 GPa.

173 tivity of cation-Cl- cotransporters, and the buildup of intra- and extracellular osmolytes, both char

174 protein complexes may be involved in optimal buildup of key factors.

175 locomotor behavior, bringing about a gradual buildup of kinematic degrees of freedom during the trans

176 lasts with LA but not oleic acid, implying a buildup of LA for aggravating such pro-fibrotic effects.

177 packaged DNA, and slows the motor before the buildup of large forces resisting DNA confinement.

178 decay time with the vesicle diameter and the buildup of large Hyp clusters in the GUV membrane.

179 ations in rRNA processing steps, including a buildup of larger rRNA precursors and a depletion of sma

180 Metabolic treatments that blocked the buildup of LCFAs potently inhibited caspase-2 activation

181 Here we report a striking buildup of lipid droplets in microglia with aging in mou

182 ures, manifestation of altered behavior, and buildup of lipofuscin.

183 MBL box modeling calculations show that buildup of MClDMS at night from the Cl2 + DMS reaction l

184 Hg-methylating microbes to net formation and buildup of MeHg in O horizons after forest harvest.

185 d polymersome fusion, which operates via the buildup of membrane tension exerted by the growing polym

186 ties in transmission have contributed to the buildup of MERS-CoV epidemics in KSA.

187 The buildup of microbes and their extracellular polymeric ma

188 Together, these conditions can promote the buildup of misfolded proteins in the ER to cause ER stre

189 the endoplasmic reticulum (ER), leading to a buildup of misfolded proteins in this organelle--a condi

190 ve to wild-type pol gamma, indicating that a buildup of mitochondrial genomic mutations may contribut

191 ful arthritic inflammatory disease caused by buildup of monosodium urate (MSU) crystals in the joints

192 ssing and surveillance was disrupted, 2) the buildup of mRNAs near transcription sites in 3'-end proc

193 This formal synthesis features a rapid buildup of much of the complexity of the target through

194 L2 suppressed aggresome formation and caused buildup of multiple cytoplasmic aggregates.

195 A gradual buildup of neuronal activity known as the "readiness pot

196 We recorded EPSCs and IPSCs to examine the buildup of neuronal activity preceding SWRs and analyzed

197 Our study implies that the buildup of newly introduced deleterious mutations (i.e.,

198 ity packing of their genomes by limiting the buildup of nonequilibrium load forces on the motor.

199 te-of-charge heterogeneity by mitigating the buildup of nonuniform internal stresses associated with

200 is attributed to the effective intratumoral buildup of PAL/HCQ, which otherwise exhibit distinctly d

201 isorders characterized by the intralysosomal buildup of partially degraded metabolites.

202 all three Arctic Ocean basins likely reflect buildup of PCBs transported from the shelf seas and from

203 eleton in MCs stimulated to migration is the buildup of pericentral actin clusters that prevent cell

204 ectly frequent cleaning of the home to avoid buildup of pesticide residues.

205 glycolytic metabolism carry the risk of the buildup of phosphosugars, which can inhibit growth at hi

206 in off-cycle adduct formation, presumably as buildup of PhS(-) becomes significant.

207 multifactorial disease characterized by the buildup of plaque in the arterial wall.

208 was reused several times, likely due to the buildup of polymerization byproducts that degraded upon

209 s of synaptic vesicles were fused, the rapid buildup of presynaptic cytosolic Na(+) promoted vesicle

210 Our finding reveals significantly slower buildup of quasiparticles in the superconducting state t

211 The buildup of radiation damage in ion-irradiated crystals o

212 g reductive treatment, and the potential for buildup of reducing species, will impact the long-term s

213 entrainment functionally contributes to this buildup of rhythmic streams or whether it is merely an e

214 omatization energies no longer outweighs the buildup of ring strain in the final reaction step (DFT c

215 micro tomographic study of the morphological buildup of Sandstones.

216 the formation of intermediate water, and the buildup of sea-ice around Antarctica, with implications

217 ciency, our lipidomics analysis revealed the buildup of several species of glycerophospholipids and o

218 Further, during OLED operation, a localized buildup of slow-decaying(14) triplet excitons and charge

219 ydrolysis, the loss of fluorescence, and the buildup of small oligopeptide products.

220 the role of cyclone activity on the seasonal buildup of snow on Arctic sea ice using model, satellite

221 levant Mn(III/IV) oxides is inhibited by the buildup of solid-phase Mn(II/III), specifically in inter

222 contribute to-and risk damage from-a growing buildup of space debris and other satellites.

223 The buildup of steady-state (time-invariant) ion concentrati

224 this system, rather than differences in the buildup of stimulus-response habits themselves.

225 consumption in its deep waters leads to the buildup of sulfide from sulfate reduction.

226 +) organisms occurred prior to a significant buildup of sulfide in pore waters.

227 This buildup of SUMOylated proteins was evident within 3-4 h.

228 n synthesis with cycloheximide prevented the buildup of SUMOylated proteins, they appeared to be newl

229 This action concomitantly suppresses the buildup of synaptic proteins in neuronal cell bodies, he

230 n highly disordered patterns, as well as the buildup of tensile stress throughout the tissue.

231 The randomness of stepping leads to a buildup of tension in the linkage between motors-which i

232 The mechanism involves a photoinduced buildup of tension in the polymer, with a negligible inf

233 rdination of motility forces that leads to a buildup of tension in the tissue, which may enhance cell

234 ked actomyosin network into a bundle and the buildup of tension occurring during the transformation.

235 this arabinose donor to then be used in the buildup of the arabinan domains of AG and LAM.

236 re of oxidant and carboxylic acid avoids the buildup of the diazo compound.

237 amplifiers have typically been based on the buildup of the field from the spontaneous emission backg

238 pathway one-electron chemistry, reducing the buildup of the inactive compound II state and reducing t

239 a40 folding to the Fbeta state, favoring the buildup of the mature fibril morphology while omitting c

240 eps of foldon addition, revealing a stepwise buildup of the native structure via a single dominant pa

241 xA can activate the stress response owing to buildup of the phosphorylated response regulator (CpxR a

242 librium constant (K(D)), is required for the buildup of the polymer, for example, amyloid fibrils.

243 as an enhancement of the signal, caused by a buildup of the protein-surfactant-electrolyte anion asse

244 ments resonant at 165 ppm show an incomplete buildup of the REDOR data to approximately 90% of the ex

245 les remain unclear, as does the evolutionary buildup of the S locus.

246 ces of these manipulations on the perceptual buildup of the target stream (the time required to recog

247 ing the influence of stimulus rivalry on the buildup of the threshold elevation aftereffect, a form o

248 ATP synthase activity in ntrc resulted in a buildup of the thylakoid proton motive force with subseq

249 e plaque defect of the eda mutant was due to buildup of the toxic intermediate 2-keto-3-deoxy-6-phosp

250 (i) The development of new products and the buildup of their in-use stocks result in the increase in

251 ibution of water and air temperature for the buildup of thermal stress.

252 ctive motor preparation signal; however, the buildup of this motor-specific process significantly lag

253 ting in which the RNA synthesis leads to the buildup of torsion in DNA.

254 ceramide transfer out of the ER prevents the buildup of toxic amounts of ceramides.

255 n promotes complete mRNA decay, avoiding the buildup of toxic endo-cleaved mRNA decay intermediates.

256 and overwhelmed, resulting in the selective buildup of toxic lipid species, which worsens the pro-in

257 onooxygenase, which is needed to prevent the buildup of toxic products during hypoxic metabolism and

258 n concert with known RQC pathways to prevent buildup of toxic proteins.

259 mote cardiovascular health by preventing the buildup of toxin precursors.

260 rmore, inhibition of the proteasome causes a buildup of translational repressors, such as polyadenyla

261 creased, which could potentially explain the buildup of ubiquitin protein.

262 otoxic stress, which is characterized by the buildup of ubiquitinated proteins that cannot be degrade

263 This causes a buildup of unengulfed cell debris.

264 from Israel (2009-2016) to evaluate how the buildup of vaccine-associated immunity in children was a

265 a late stage in virus infection and caused a buildup of virions within cells.

266 CP and the secretory pathway, resulting in a buildup of virions within dilated ER vesicles.IMPORTANCE

267 old seep systems typically exhibit extensive buildups of authigenic carbonate minerals, resulting fro

268 We showed that positive supercoiling buildup on a DNA segment by transcription slows down tra

269 similar to those in studies of organic film buildup on indoor windows.

270 n)Abeta), the action and the role of Abeta42 buildup on synaptic function have been poorly investigat

271 this H(+) transfer, forcing negative charge buildup on the Au and increasing the transition state en

272 e that has considerably less positive charge buildup on the incoming nucleophile and an enhanced leav

273 The erosion rate decay and surface roughness buildup, on the other hand, exhibit a rather sudden dela

274 The slower buildup only occurs when the pump pulse is too weak to d

275 After a buildup period, contamination levels of meat peaked by J

276 provide new insight into the dynamics of the buildup process in the double-slit experiment, and can b

277 The buildup rate of the CPP also strongly predicted reaction

278 ribed in sequential sampling models: (1) its buildup rate systematically scaled with sensory evidence

279 s that modulating neuronal latencies and the buildup rates of developing motor plans are two key neur

280 xperimental observations of radiation damage buildup remains elusive.

281 Because the buildup, renewal, renovation, maintenance, and operation

282 espiration and reactive oxygen species (ROS) buildup, resulting in oxidative-stress-induced cell deat

283 AD/CAM zirconia abutments veneered with hand buildup technique.

284 abutment; Institut Straumann AG) with a hand buildup technique.

285 The electron density buildup that is observed at the Fe(II) center in the pre

286 y weighting and contained a choice-dependent buildup that was distinguishable from motion integration

287 n, endogenous fructose accumulation, and fat buildup that was significantly reduced by co-administrat

288 causes of concern, including its accelerated buildup, the early age of disease onset in the populatio

289 Indeed, the measured characteristic buildup time of the dye emission is much longer than the

290 e latter is very close to the characteristic buildup time of the dye emission.

291 y caused a cyclic 4-Hz pattern in perceptual buildup time.

292 erve as high-affinity cross-links with force buildup times that exceed physiological timescales; and

293 escribed distributions, ranging from gradual buildup to sudden delivery, based only on the channel di

294 fluence, we dissect the dynamics of pressure buildup toward a steady-state value, consistent with the

295 t of the contingent negative variation (CNV) buildup toward the expected off-beat time.

296 the prevailing capacity fading and impedance buildup under high-voltage cycling conditions, as well a

297 Rate increases were especially prominent in buildup units.

298 Signal intensity buildup was fit to a recursive model that regionally sol

299 interaction could reduce intraneuronal Abeta buildup, we used a noncontact neuronal-astrocytic co-cul

300 rallel microtubules apart with gradual force buildup while parallel microtubule bundles remain statio