ライフサイエンスコーパス: bump

1 ance of the resulting model ("Generalization Bump").

2 d 30 (the so-called autobiographical memory 'bump').

3 ously and produces unitary dark events (dark bumps).

4 ight into usable electrical signals (quantum bumps).

5 sted in the single-photon responses (quantum bumps).

6 eaflet, forming the characteristic subaortic bump.

7 hat leads to the red-giant-branch luminosity bump.

8 ger span, subjects tended to report only one bump.

9 acy in detecting those with a high number of bumps.

10 p had an amplitude similar to wild-type (WT) bumps.

11 reported whether they felt zero, one, or two bumps.

12 oduction of dark bumps but not light-induced bumps.

13 ifested in a substantially high rate of dark bumps.

14 equently reported symptoms included lumps or bumps (95%), having a crust on the skin (95%), burning (

15 spatial position signal by modulation of the bump activity levels without significantly interfering w

16 e indicates that B2 RNA operates as a "speed bump" against advancement of RNA polymerase II, and temp

17 h that the network distance between adjacent bumps always maps onto 360 degrees.

18 ID-19 recession resulted in an overall "baby bump" among US-born mothers, which marked the first reve

19 reas intracellular calcium and voltage adapt bump amplitude and waveform (sample size).

20 e stimulus average, and, simultaneously, the bump amplitude tracks stimulus uncertainty.

21 Bump amplitude was constant over the range 1.5-100 micro

22 itment to solidarity and equity, argue Jesse Bump and colleagues

23 arginalisation, and colonialism, write Jesse Bump and colleagues

24 eered BET bromodomains designed as part of a bump and hole approach.

25 n-dual-eligible beneficiaries during the fee bump and the postbump or bump extension period vs baseli

26 ed the inner disk gas and generated pressure bumps and dust traps that manifested as rings.

27 le optical profilometry was used to identify bumps and pits in a substrate which could cause catastro

28 g a specialized algorithm that removes small bumps and pockets, while preserving large-scale structur

29 reliably estimate photon times from quantum bumps and Snyder filters are then used to causally estim

30 Association between number of bumps and UFOV score was assessed in a generalized linea

31 ble beneficiaries in 2013 to 2014 (mandatory bump) and 2015 to 2016 (postbump or bump extension) vs 2

32 to detect regions of high surface roughness, bumps, and pits; in which, the majority of the defects d

33 ent membrane (interwoven ridges and grooves, bumps, and pores), which have typically been studied as

34 aken individually, produced illusory virtual bumps, and subjects reported whether they felt zero, one

35 can be achieved with any number of activity bumps, and the consequences of having more or fewer bump

36 These included increased von Frey, bumps, and warmth detection thresholds as compared with

37 ssion of an engineered glycosyltransferase, "bump-and-hole" (BH)-GalNAc-T2, boosts labeling in a prog

38 ndividual members of this family, we took a "bump-and-hole" approach and designed a series of N(6)-su

39 ased heterobifunctional degrader based on a "bump-and-hole" approach.

40 ansferase mutant/SAM analogue pairs using a "bump-and-hole" strategy.

41 Using a bump-and-hole-based chemical-genetic method, we have rap

42 and structure-activity relationships of our bump-and-hole-PROTACs using a CRISPR knock-in cell line

43 These bumps are found across primate species that span taxonom

44 and the consequences of having more or fewer bumps are unclear.

45 ss, spontaneous unitary current events (dark bumps) are produced by spontaneous single Gqalpha activa

46 tion, while single-photon responses (quantum bumps) arise from synchronous activation of several Gqal

47 asm lesion more frequently showed an intimal bump at baseline and intimal gathering during spasm comp

48 Moreover, we show that bump attractor dynamics can account for the nonuniform i

49 zed space and offer experimental support for bump attractor dynamics mediating cognitive tasks in the

50 , and, to date, no demonstration exists that bump attractor dynamics underlies spatial working memory

51 d neural excitability in a simple continuous bump attractor model can induce broader neural tuning an

52 A bump attractor model with divisive normalization replica

53 Continuous bump attractor modeling suggested neurophysiological and

54 Here, we show that a continuous bump attractor network can integrate a circular feature,

55 Continuous bump attractor networks (CBANs) are a prevailing model f

56 In these discrete bump attractor networks, we show that reducing spatial c

57 ly, we delve into the conditions under which bump attractor tuning and diffusion balance in biologica

58 A 'bump attractor' computational model can account for this

59 on or eye position), in terms of continuous 'bump attractors' and 'line attractors'.

60 of pattern separation and memory storage via bump attractors.

61 At resting potential (-70 mV), bumps averaged 10 pA in peak amplitude with a half-width

62 ngle Gqalpha activations do not produce dark bumps, because of a critical phospholipase Cbeta (PLCbet

63 overcoming one of the thiomethyl (SMe) speed bumps before proceeding on to the secondary oxyphenylene

64 ws that RET usually occurs by only a simple "bump" between partners.

65 readout integrated circuits (ROIC) by indium bump bonding which significantly increases the fabricati

66 The ion exchange reactions affected bump, bulge, and crack formation on the biotite basal pl

67 ty selectively suppressed production of dark bumps but not light-induced bumps.

68 ht-sensitive channel were very similar to WT bumps, but with slightly slower decay times.

69 fusion fluxat the apex of convex millimetric bumps by optimizing the radius of curvature and cross-se

70 ineering of paired ZDHHC 'hole' mutants and 'bumped' chemically tagged fatty acid probes enabled prob

71 boration of the base moiety so as to afford "bumped" cofactor mimics compatible with "hole"-bearing m

72 Standard Amelanotic, Bleeding, Bump, Color uniformity, De novo, any Diameter (ABCD) det

73 age (the so-called autobiographical memory "bump") compared with other time periods in their lives.

74 Using binding and structural analysis of bumped compounds, we show here that the pocket is highly

75 ed multielectrode arrays verified that these bumps contain face-selective neurons.

76 predicted by the linear summation of quantum bumps convolved with their latency dispersion.

77 roduction of single G(q)alpha-activated dark bumps despite a high rate of spontaneous G(q)alpha activ

78 chanical stimuli (von Frey monofilaments and bumps detection test) were measured.

79 showed significant inverse correlation with bumps detection threshold.

80 an induce broader neural tuning and decrease bump diffusion, provided neural rates are saturated.

81 Bump duration was unaffected by lowering the extracellul

82 timulus compared to the internally generated bump dynamics, yielding either early (primacy), uniform,

83 Sensitivity to a steric speed bump effect was found to depend on (a) structural locati

84 threading systems, the sensitivity of speed bump effects has not been evaluated as a function of str

85 Discrete events (quantum bumps) elicited by dim light were analysed in whole-cell

86 The bumps emerge during fetal development in macaques, indic

87 Across all three types, networks with more bumps experience less noise-driven deviations in bump mo

88 ries during the fee bump and the postbump or bump extension period vs baseline.

89 andatory bump) and 2015 to 2016 (postbump or bump extension) vs 2012 (prebump).

90 ng point, high surface roughness SnAg solder bump features is presented.

91 rule factory, located in the Jovian pressure-bump, followed by turbulent diffusion and concentration

92 The energy required for echinocyte bump formation was calculated for a range of bump shapes

93 Thus, if the cell is near the threshold for bump formation, the calculations predict that small chan

94 Cbeta (PLCbeta) activity level required for bump generation.

95 ined areas involved the modification of stud bump geometry with microfabricated silicon molds via an

96 owever, a second rarer (10 %) class of large bump had an amplitude similar to wild-type (WT) bumps.

97 While the general concept of steric speed bumps has been demonstrated in rotaxane shuttles and mac

98 Energy minima corresponding to nonzero bump heights were found when the stress-free area differ

99 The bump-hole approach is a powerful chemical biology strate

100 Our results indicate that the bump-hole technique can be used to identify Abl family k

101 We applied the bump-hole technique, pioneered by Shokat and colleagues,

102 erentially methylated regions (DMRs) using a bump hunting approach and a permutation-based multiple t

103 hylation studies with small sample size, the bump hunting method and the empirical Bayes method are r

104 For all sample sizes, the bump hunting method had the lowest stability in terms of

105 oss CpG loci are independent, while only the bump hunting method is recommended when DNA methylation

106 Only the bump hunting method showed appropriate FDR control and t

107 ermutation test, empirical Bayes method, and bump hunting method.

108 in each group), both the empirical Bayes and bump hunting methods showed appropriate FDR control and

109 Here, we demonstrate that applying bump hunting via the patient rule induction method (PRIM

110 (i) implementing a computationally efficient bump-hunting approach to identify DERs that permits geno

111 ration in the microwave regime of cloaking a bump in a surface.

112 a unique signature: There was a substantial bump in March, aligning with pandemic onset and lockdown

113 and facilitates the formation of an intimal bump in patients with vasospastic angina.

114 triangular current ramp, which emulates the bump in synaptic input received while traversing the pla

115 When runners encounter a sudden bump in the road, they rapidly adjust leg mechanics to k

116 However a large bump in the termination region of the JTE or a deep pit

117 edia attention, may have experienced a small bump in vaccinations compared with the control zip codes

118 ing CNV or was seen as a sheet with numerous bumps in eyes with GA.

119 Our findings provide motivation for multiple bumps in the mammalian grid network.

120 Bumps in the track do not significantly disturb NS3 unwi

121 Quantum bumps in trp mutants lacking the major class of light-se

122 Bumps in trpl mutants lacking the second class of light-

123 and high levels of deuteration artifactual "bumps" in (15)N R(1rho) BMRD profiles are common.

124 aised quite dramatically by inserting "speed bumps" in the form of steric and/or electrostatic barrie

125 of generating elementary responses, quantum bumps, in response to single photons using a stochastica

126 Following each bump, individual microvilli are rendered briefly (~100-2

127 The bump interval and amplitude distributions, and the 'freq

128 higher the density, the more often the ants bump into each other.

129 n motion argues that enzymes will eventually bump into substrates, this probability is greatly enhanc

130 iated with driving cessation and limitation, bumping into objects, slower walking, and falls.

131 small wood chip floating down a slow stream, bumping into various objects tossed and turned hither an

132 The multilayer solder bump is a lead free ternary solder system, which provide

133 The 2021 to 2022 baby bump is especially remarkable given the large declines i

134 can occur during CO-CO collisions, whereby a bump is followed by a move similar to a "do-si-do" in sq

135 esults demonstrated P-glycoprotein decreases bumped kinase inhibitor enterocyte exposure, resulting i

136 rized the effect of P-glycoprotein efflux on bumped kinase inhibitor pharmacokinetics and efficacy.

137 Bumped kinase inhibitors (BKIs) have been shown to be po

138 Bumped kinase inhibitors (BKIs) of Cryptosporidium parvu

139 Bumped kinase inhibitors (BKIs) specific for parasite ca

140 testinal drug concentrations for a series of bumped kinase inhibitors (BKIs) that have nearly identic

141 We exploited this to develop bumped kinase inhibitors (BKIs) that selectively target

142 ew class of transmission-blocking compounds, bumped kinase inhibitors (BKIs), which inhibit microgame

143 elective 5-aminopyrazole-4-carboxamide-based bumped-kinase inhibitors (BKIs) are effective in both in

144 he intrinsic noise components, which include bump latency (mean delay and jitter) and shape (amplitud

145 Bump latency increased by ca 50 % between 1.5 mM and 100

146 neurons represents the animal's heading via bump-like activity dynamics.

147 on their heading preferences, can sustain a bump-like activity pattern whose location can be updated

148 varied the spatial separation between these bump-like force-feedback regions, from being much greate

149 -type symbiosis, but instead developed small bump-like nodules on its roots that were blocked at an e

150 ith a 4.9% increase (P = 0.004) in number of bumps made over the course.

151 se, seeded with obstacles, and the number of bumps made while traversing the course was counted.

152 ion of individual elements inside the solder bump matrix.

153 onal epiretinal proliferation and a retinal "bump." Moreover, it often presented with early ellipsoid

154 s experience less noise-driven deviations in bump motion.

155 eory for path integration and noise in multi-bump networks.

156 Under this mapping, bump number does not significantly affect the amount of

157 uron represents a fixed length no matter the bump number.

158 ng 1D ring attractor networks with different bump numbers and characterizing their responses to three

159 opulation initially encoded a narrowly tuned bump of activation centered on the peripheral memory tar

160 accuracy and produces a narrower and higher bump of activity.

161 omers toward the tip, even the concentration bump of G actin that they create before they jam is enou

162 (a dielectric cylinder with a nanoscale-high bump of the effective radius) can exactly imitate a quan

163 were never admitted, 39 were admitted after bumping of another patient, and 89 were admitted on subs

164 ping may alter VT inducibility by mechanical bumping of critical sites.

165 To do so, these networks produce localized bumps of activity that move coherently in response to ve

166 There is an increase or "bump" of cell density 3.5-4.0 mm from the foveal pit, co

167 er, in a phenomenon akin to the nonspecific "bumping" of closely apposed domains.

168 The 'bump' of activity in the ring can be updated by idiothet

169 zation mechanism that unifies the so-called "bump-off" and "switching" models.

170 eously produces a hexagonal grid of activity bumps on a two-dimensional sheet of units.

171 This system enables detection of protein bumps on the DNA and localization of their binding sites

172 aine dyes with different substituents (speed bumps) on the flanking chains and two macrocycles with d

173 s when viewing images containing clusters of bumps or holes.

174 n be controlled by introducing steric "speed bumps" or electrostatically switchable gates.

175 and anatomical imaging, we show that small "bumps," or buried gyri, along the lower bank of the supe

176 olecules (responsible for quantal potential "bumps") produces a photoreceptor generator potential.

177 nclear how phototransduction suppresses dark bump production arising from spontaneous G(q)alpha activ

178 of spontaneous G(q)alpha activation and dark bump production potentially hampers single-photon detect

179 ically adjusting availability of microvilli (bump production rate: sample rate), whereas intracellula

180 level of PLC activity is required to induce bump production.

181 our cellular and mechanistic data qualifies bumped PROTAC AGB1 as a potent, fast, and selective degr

182 ows direct recruitment by heterobifunctional bumped proteolysis targeting chimeras (PROTACs) to hijac

183 n ultrasmooth pure metal films with grooves, bumps, pyramids, ridges, and holes.

184 to adaptively transduce photons into quantum bumps (QBs, or samples).

185 n these strains are populated by a series of bumps ranging between 7 and 40 nm in diameter, depending

186 bumps were virtually absent and the quantum-bump rate was reduced, indicating that Ca(2+) release fr

187 Our results support a diffusing bump representation for spatial working memory instantia

188 Conclusion: The BUMP score accurately distinguished UBU from bone metast

189 Compared with the visual assessment, the BUMP score provided added value in terms of specificity

190 The BUMP score's AUC was significantly higher than that of H

191 ore, the bone uptake metastatic probability (BUMP) score, achieving an area under the receiver-operat

192 ighlight three of the most common 'lumps and bumps' seen in childhood: nevus sebaceus, pilomatricoma

193 opes and saturation rates, and nonmonotonic (bump-shaped) interactions with varying modes and amplitu

194 bump formation was calculated for a range of bump shapes for different preferred curvatures.

195 formed for evaluation of these asymptomatic "bumps" should be considered when decisions are made with

196 the INAD scaffolding molecule is disrupted, bumps showed a defect in quantum bump termination, but t

197 accumulations of ribosomes-which we term 'W-bumps'-showed that they were characterized by ribosomal

198 ongoing replication, analogous to how speed bumps slow down cars.

199 ing of spontaneously formed tuning curves or bump solutions.

200 When the bump spacing was the same as the finger span, subjects t

201 The number of people who experienced bumps, stumbles, or orientation problems was almost twic

202 bulin islands may act as stop signs or speed bumps, switching a shortening microtubule back into a gr

203 disrupted, bumps showed a defect in quantum bump termination, but their amplitudes and latencies wer

204 Bumps that are rationally designed to integrate these me

205 dermal mesenchyme into a pattern of surface bumps that triggers epithelial gene expression.

206 Remarkably, this bump then spread inward toward foveal locations, forming

207 nal appearance of the body, such as the baby bump, there are also substantial changes taking place wi

208 ted by brief highly synchronous volleys, or "bumps." These bumps were typically so brief that they co

209 or neural network causes the neural activity bump to oscillate around the external input, resembling

210 graft centration with a cannula; and bubble bumping to unfold peripheral inward folds.

211 n asymmetry in the model allows the activity bumps to be shifted in any direction, at a rate proporti

212 ss in academia and to highlight the positive bumps to my chip on the steam that affected the directio

213 rons at the theta frequency causes attractor bumps to oscillate in speed and size, which gives rise t

214 es to that of Medicare for 2013 to 2014 (fee bump) to help accommodate potential increases in demand

215 which the position of the network's activity bump tracks the stimulus average, and, simultaneously, t

216 es and deliver them sunwards of the pressure bump via Lindblad torque flows.

217 An intimal bump was defined as 1 or more intimal projections into t

218 The baby bump was most pronounced for first births and women unde

219 Above age 25, the baby bump was most pronounced for women aged 30 to 34 and wom

220 ctural location, being lowest when the speed bump was near the end of a flanking chain, and (b) macro

221 The ACA fee bump was not associated with increases in primary care v

222 A series of five pH bumps were applied to elute E. coli tryptic peptides fro

223 Bumps were automatically detected and analysed for ampli

224 At intermediate [Ca2+]o bumps were biphasic with a slow rising phase followed by

225 of eyes, while small RPE elevations and RPE bumps were detected in 31.8% and 22.7% of eyes, respecti

226 These bumps were present in monkeys raised without seeing face

227 ighly synchronous volleys, or "bumps." These bumps were typically so brief that they could not be wel

228 In IP3R-deficient photoreceptors, dark bumps were virtually absent and the quantum-bump rate wa

229 ontinuous attractor networks can employ more bumps when encoding linear coordinates; this advantage d

230 achieved using plasma density down-ramps or bumps, which perturb the LWFA bubble phase velocity by v

231 thm characterized by a distinctive spectral "bump," which is coherent across widely separated sites.

232 udy was to determine the association between bumping while walking and divided visual attention, as m

233 by processing speed, independently predicted bumping while walking.

234 l attention is a significant risk factor for bumping while walking.

235 trial, dopamine activity should resemble a "bump," whose ramp-up phase should, furthermore, be great

236 sequentially electroplated multilayer solder bump with tailored transformation imprinted melting poin

237 decrements in mobility and increased risk of bumping with worsening visual field function.