ライフサイエンスコーパス: bundle

1 ier a filament has to overcome for joining a bundle.

2 tance between the aortic annulus and the His bundle.

3 hanical responsiveness of an individual hair bundle.

4 is, and forming a basket-like pentamer helix bundle.

5 rotein-coupling seven-transmembrane-spanning bundle.

6 C in shPAB cell cultures and in shPAB muscle bundle.

7 ymal progenitors to the airway smooth muscle bundle.

8 d contact with the core 7-transmembrane (TM) bundle.

9 stem's capabilities at the level of the hair bundle.

10 erning, and reduced cell numbers in vascular bundles.

11 transects the rootlets of microvillar actin bundles.

12 hem reassemble into electrostatically stable bundles.

13 rovides mechanical coupling between the hair bundles.

14 and a discontinuous distribution of vascular bundles.

15 ies; and clinical guidelines, protocols, and bundles.

16 6.5 buffer ZipA induced PaFtsZ to form large bundles.

17 clude the formation of microtubules or actin bundles.

18 ponding to a rigidification of the six-helix bundles.

19 The RNFL was seen as arcuate hyperreflective bundles.

20 cunae surround extracellular collagen fibril bundles.

21 g to generate mechanically stiff actin super-bundles.

22 a robust circumferential alignment of actin bundles.

23 is evaluated numerically for multi-helix DNA bundles.

24 es in specific locations of the white matter bundles.

25 ated at row 2 tips like they do in wild-type bundles.

26 ology and the crystallinity of the cellulose bundles.

27 alescence was restricted by keratin filament bundles.

28 considerably lower levels than in wild-type bundles.

29 g systemic signaling, occurs at the vascular bundles.

30 ent network itself is determined by filament bundling.

31 nhance the later developmental event of axon bundling.

32 ce plays a crucial role in mediating F-actin bundling.

33 ed HUalphaalpha dependent intermolecular DNA bundling.

34 hem and antagonized UNC-87-mediated filament bundling.

35 oss-talk and consequently inhibiting F-actin bundling.

36 tically segmented RNFL in the papillomacular bundle (-15 to +15 degrees relative to the fovea-optic n

37 roteins, that bind the N-terminal four-helix bundle (4HB) "killer" domain and neighboring first brace

38 e individualized anatomic single- and double-bundle ACL reconstruction techniques.

39 We found that ExoY can directly bundle actin filaments with high affinity, comparable wi

40 In vitro, UNC-87 bundled actin filaments, whereas CLIK-1 bound to actin f

41 yo-electron tomography, we show that dynamin bundles actin while forming a helical structure.

42 ulatory activities, but their distinct actin-bundling activities suggest that they also have differen

43 of Ena/VASP, its surface recruitment or its bundling activity all reduce Ena/VASP's ability to maint

44 tic ACTN4 demonstrated increased binding and bundling activity with F-actin in vitro.

45 dues in FL villin that regulate its filament-bundling activity.

46 We found that patients with high ABCDE bundle adherence (>= 60%) had significantly decreased od

47 to estimate the potential effect of improved bundle adherence on healthcare costs and quality-adjuste

48 ervention, we determined the impact of ABCDE bundle adherence on inpatient and 1-year mortality, qual

49 ssion models to determine the impact of high bundle adherence on inpatient mortality, discharge statu

50 incremental cost-effectiveness ratio of high bundle adherence was $15,077 (95% CI, $13,675-$16,479) p

51 High bundle adherence was associated with a 0.12 increase in

52 BUndle ANalytics (BUAN) is a fast, robust, and flexible

53 etter understood in the context of the fiber-bundle anatomy highlighted by this study.

54 novel fold primarily consisting of a 3-helix bundle and a beta-sandwich.

55 Atypical microstructure of the cingulum bundle and anterior thalamic radiation was associated wi

56 i1+ PDLSCs are surrounding the neurovascular bundle and more enriched in the apical region.

57 'brace' that connects the killer four-helix bundle and regulatory pseudokinase domains.

58 e were more conduction disorders at Bachmann bundle and this area has a higher incidence of CD (4.4%

59 We demonstrated that actin bundles and Ae-Forked are required for bristle elongatio

60 ugh the dermis, subcutis, orbicularis muscle bundles and nerve fibers; the tumour cells were noted to

61 arvae retain normal gross morphology of hair bundles and proper trafficking of known MET components P

62 33(+) muscle mSCs and both large-fiber nerve bundles and small-fiber sensory neurons; report that mus

63 ion aligns F-actin in predominantly unipolar bundles and stabilizes them against depolymerization.

64 or the maintenance of contractile actomyosin bundles and that Tmod-dependent capping of actin-tropomy

65 ed cells, and between blood vessels or nerve bundles and their associated basement membranes.

66 aments to associate into long straight loose bundles and/or sheets at both pH 6.5 and pH 7.5, which h

67 ardial mapping of the right atrium, Bachmann bundle, and left atrium during sinus rhythm.

68 ound microtubules and cross-linked them into bundles, and increased their resistance to the disassemb

69 ctin cytoskeleton both directly, via F-actin bundling, and indirectly, via actin-activated nucleotidy

70 fascin phosphorylation can regulate F-actin bundling, and that this modification can contribute to s

71 The mechanical properties of these bundles are critical for proper force transmission and f

72 s after Ca(2+) chelation, especially if hair bundles are deflected toward their short edges.

73 ISPR-Cas9 gene editing, we showed that actin bundles are required for shaping bristle, hair, and scal

74 In scales, actin bundles are required for width formation.

75 epolarizations in the atrioventricular (His)-bundle associated with lethal ventricular arrhythmias.

76 hat the M8R mutation disrupts the four-helix bundle at the head-to-tail junction, leading to weaker t

77 tron microscopy revealed dynamin along actin bundles at the fusogenic synapse.

78 ane diffusion parameters in medial forebrain bundle axonal tracts connecting midbrain somatodendritic

79 o straight and too far apart to form tangled bundles based on their intrinsic, undeformed geometry al

80 ild heart failure (HF) patients without left bundle branch block (LBBB) did not derive a significant

81 Sd) >=150 ms and subjective labeling of left bundle branch block (LBBB).

82 rsely correlated with the presence of a left bundle branch block (P<0.01).

83 normal subjects; (5) 18 patients with right bundle branch block (RBBB).

84 ses and by observing a VA increase with left bundle branch block in 2 cases.

85 Left bundle branch block may also develop following aortic va

86 Left bundle branch block may be due to conduction system dege

87 lure with reduced ejection fraction and left bundle branch block may respond positively to cardiac re

88 od may assist in objective classification of bundle branch block morphology in CRT.

89 HBP can also overcome bundle branch block patterns, and data are accumulating

90 h NSVT or VT, the dominant morphology (right-bundle branch block with superior axis) was 100% predict

91 athophysiologic and clinical aspects of left bundle branch block, as well as current and future strat

92 rdiographic abnormalities (long PR, complete bundle branch block, left ventricular hypertrophy voltag

93 ectrocardiography showed sinus rhythm, right bundle branch block, T-wave inversion in V6, and evidenc

94 lvement, and electrical abnormalities (right bundle branch block/low voltages) was developed to predi

95 Left bundle branch pacing (LBBP) has recently emerged as a pr

96 bitory brace helix alpha6 and the four-helix bundle by stacking to Phe148.

97 The filaments inside the bundle cannot be continuously actuated, nor can they eas

98 These successes have spurred the creation of bundled care mandates by major healthcare payers, such a

99 The cingulum bundle (CB), specifically the dorsal anterior portion of

100 diated by long-range myelinated axonal fiber bundles, collectively termed as white matter.

101 dopt two very different homotrimeric helical bundle conformations-one short (~66 angstrom height) and

102 This bundle connected frontal regions to the STN.

103 n the uncinate fasciculus, the primary fiber bundle connecting the amygdala to the orbitofrontal cort

104 Changes in DNA bundling consequently affects gene expression globally,

105 te that a mode where a pushing and a pulling bundle cooperate is the only possibility to enable both

106 Implementing the cleaning bundle cost $349 000 Australian dollars (AUD) and genera

107 Widespread utilization of such a bundle could therefore lead to significantly improved ou

108 sequence of conformational changes in the S6 bundle crossing and the selectivity filter leading to ch

109 Both the selectivity filter and bundle crossing expand upon activation, accompanied by s

110 oscopy experiments we show that vinculin can bundle dendritic actin networks through rapid binding an

111 EA) study for the assessment of a ring stent bundle deployed under a variety of aortic cross-sections

112 expressed during the late stages of vascular bundle development and localizes around forming pits and

113 ctin-bound structure, the first helix of the bundle dissociates and the remaining four helices and co

114 Scale actin-bundle distribution changes from the symmetrical organiz

115 Here we demonstrate that a six-helix bundle DNA origami nanostructure in the submicrometre sc

116 sis, SNARE assembly into a stable four-helix bundle drives membrane fusion.

117 -step explanation for the formation of actin bundles due to mechanical stimulation and provide new in

118 cells and SGNs are important for proper axon bundling during development.

119 requires extensive actin polymerization and bundling during development.

120 Warfarin care bundles (e.g. genotype-guided warfarin dosing, patient's

121 y, but not those requiring stable actomyosin bundles, e.g., focal adhesion elongation or migratory fr

122 que of mechanically coupling two active hair bundles, enabling us to probe the dynamics of the couple

123 cluding the kinocilium and the V-shaped hair bundle essential for mechanotransduction.

124 tes this effect by changing location of hair bundle establishment or positions of HCs since daughter

125 -26 [95% CI: -31, -21]) coinciding with code-bundling events instituted by Medicare (CT, nuclear imag

126 A bundled, evidence-based approach to improving hospital c

127 internal dynamical processes in cytoskeletal bundles: filament assembly and disassembly, the attachem

128 -effectiveness of the environmental cleaning bundle for reducing the incidence of HAIs.

129 omeric pinhole (right-handed heptameric TMD2 bundle), for the active dimer (right-handed Gly-zipped T

130 gest that dynamin 1 supports the microtubule bundle formation and participates in the stabilization o

131 ovide a molecular basis for coordinate actin bundle formation at nascent adhesions.

132 micromolar Zn(2+) concentrations, but strong bundle formation is observed at a concentration of 100 m

133 s before chemical adaptation during filament bundle formation: actin filaments first align in the dir

134 Strikingly, alpha-helical bundles formed from the extended C-termini of capsid pro

135 ustered vinculin can initiate and immobilize bundles from mobile Arp2/3-branched networks.

136 Using hair bundles from the rat's cochlea and the bullfrog's saccul

137 ral subsystem includes the lateral forebrain bundle, functionally mediating voluntary behavior and co

138 Although the dynamics of individual hair bundles has been extensively investigated, the influence

139 e thought to be homologous structures, actin bundles have a differential requirement in shaping mosqu

140 vinculin promotes stable but flexible actin bundles having a mixed-polarity organization, as confirm

141 hemodynamic effects of LVs with BiV and His bundle (HB) pacing in CRT patients.

142 this we first modified the designed helical bundle hemoprotein H4, creating a highly charged protein

143 ed QRS duration, as well as atrioventricular bundle hypoplasia after birth in heterozygous mice.

144 ct that bacteria can passively form coherent bundles, i.e. bundles which do not contain tangled pairs

145 LRRK2 G2019S knockin, the dopaminergic axon bundle in the midbrain was significantly widened and app

146 diameter) in pH 7.5 solution and formed some bundles in pH 6.5 solution.

147 inly expressed in phloem of diffuse vascular bundles in the nodes and the axillary meristem.

148 porting Zn to the phloem of diffuse vascular bundles in the nodes for subsequent distribution to TBs

149 In contrast, microtubule bundling in biopsies 2 to 3 days after the first dose of

150 n immunofluorescence to quantify microtubule bundling in interphase cells and aberrant mitoses.

151 s that in solution leptin forms a four-helix bundle including a pierced lasso topology.

152 to receive either usual care (COPD discharge bundle including PR information leaflet) or usual care p

153 the clinical efficacy of single- and double- bundle individualized anatomic anterior cruciate ligamen

154 h the electrolyte ions are excluded from the bundle interior.

155 The care bundle intervention was independently associated with a

156 -based discussions; and incorporation of the Bundle into the Electronic Health Record.

157 Additionally, BUAN takes the shape of the bundles into consideration for the analysis.

158 aps, and sensitivity curves that show a hair bundle is desensitized by efferent stimulation.

159 pattern by changing the location where hair bundle is established in HCs.

160 HC) will always perturb AVRT because the His bundle is obligatory to the circuit.

161 nesis and maintenance of these stereociliary bundles is a tightly regulated process requiring the inv

162 The advantage of sheathed flagella bundles is the high rigidity, making high swimming speed

163 uding the epidermis, mesophyll, and vascular bundle, its tissue-specific functions in thermomorphogen

164 However, it remains unknown how bundle length and buckling are controlled by external ph

165 nisotropic structures to further develop the bundle-like geometry.

166 ions were found in unique groups of six hair bundle link proteins.

167 d the codon level for five of these six hair bundle link proteins.

168 s from the symmetrical organization of actin bundles located throughout the bristle membrane to an as

169 likely benefits of guideline-directed sepsis bundles, mandated treatments in sepsis may lead to unint

170 ptions at specific locations of the cingulum bundle may be a hallmark for the early prediction of Alz

171 m criticality suggested that individual hair bundles may be regarded as nonisochronous oscillators.

172 he opposite state, in support of the rocking-bundle mechanism as the driver of conformational change.

173 were defined as the cost of implementing the bundle minus cost savings from fewer infections.

174 This makes the formation of coherent bundles more robust against the passive nature of the bu

175 to the ankle-link region in developing hair bundles moreover depends on the presence of PCDH15-CD1 a

176 ereociliary proteins involved in normal hair bundle morphogenesis, such as CDC42, RAC1, EPS8 and ESPN

177 nnecting neighboring stereocilia during hair bundle morphogenesis.

178 substitutions consistent with abnormal hair bundle morphology and reduced hearing sensitivity.

179 s with displacement clamping to control hair bundle motion and measure forces.

180 ant trend changes in modalities without code bundling (MRI, radiography, US), although flat trends mo

181 mation, suggestive of the postfusion 6-helix bundle; NPC1 binding further promoted transition to the

182 The hair bundle of cochlear hair cells is the site of auditory me

183 A fiber-optic fiber attached to a bundle of drivable microwires was later implanted into t

184 Lower FA within the cingulum bundle of hippocampus and cerebrospinal tracts were the

185 e ligand binding pocket at the transmembrane bundle of the receptor, which subsequently couples to th

186 lassy behavior involving collective creep of bundles of 2D pancake vortices as well as temperature- a

187 Bundles of actin filaments are central to a large variet

188 , we present a biophysical model for dynamic bundles of actin filaments submitted to an external load

189 Cell migration entails networks and bundles of actin filaments termed lamellipodia and micro

190 l and systemic ROS signaling at the vascular bundles of Arabidopsis.

191 sed on tendons, which contain highly aligned bundles of collagen.

192 he position of self-assembled microfibrillar bundles of cyclic peptide nanotubes in water droplets.

193 e and the spatial position of microfibrillar bundles of cyclic peptide nanotubes.

194 Bundles of cytoskeletal filaments and molecular motors g

195 initiation of protein synthesis, into large bundles of filaments.

196 ube arises from the assembly of two distinct bundles of helical filaments that have the same helical

197 o investigate this, we simulated cylindrical bundles of MTs that are cross-linked and powered by mole

198 proaches, gammaPNA structures appear to form bundles of nanofibers.

199 ales in single supramolecular nanofibers and bundles of nanofibers.

200 Here we show that bundles of single walled carbon nanotubes (SWNTs), synth

201 Mechanosensory bundles on auditory sensory cells are composed of stereo

202 by interdigitating MTs that form interpolar bundles or by astral MTs connected to the cell cortex.

203 ays cells in mitosis and impairs microtubule bundle organization and dynamics.

204 ricted, resulting in two regions of opposite bundle orientation (Jiang et al., 2017).

205 that transcription factor Emx2 reverses hair bundle orientation and its expression in the mouse vesti

206 e, we investigated establishment of opposite bundle orientation in embryonic utricles by live-imaging

207 es to form two daughter HCs of opposite hair bundle orientations.

208 tion, hair bundle stiffness, and spontaneous bundle oscillation can occur within seconds after Ca(2+)

209 is also higher, particularly in the Bachmann bundle (P=0.008) and pulmonary vein (P=0.020) areas.

210 His bundle pacing (HBP) results in physiological ventricular

211 e seen further insights into the role of His bundle pacing on improving outcomes.

212 on reason for performing LBBP was a high His-Bundle pacing threshold (n=23) at implant.

213 ending seem to be well-aligned in Medicare's bundled payment initiative for bariatric surgery.

214 vers in the context of a nationwide Medicare bundled payment reform that was implemented in some area

215 a national voluntary payment demonstration, Bundled Payments for Care Improvement (BPCI) model 3, in

216 Medicare's bundled payments for care improvement-advanced program i

217 Further research is needed to assess bundled payments in other clinical contexts.

218 Bundled payments may prompt hospitals to implement broad

219 g outcomes indicates that some warfarin care bundles perform as well as NOACs.

220 ofessional team rounds in the ICU to improve Bundle performance.

221 s in confined environments and that vimentin bundling perturbs cell-mechanical properties and inhibit

222 ulators and late Six1 deletion disrupts hair-bundle polarity.

223 onin protein expression in sensory hair cell bundles, prevents hair cell loss, improves hearing sensi

224 We evaluate the kinetics of the bundling process by considering the energy barrier a fil

225 The bundling process can be reproduced in artificial conditi

226 ore robust against the passive nature of the bundling process, where the position of individual filam

227 agement, and Early exercise/mobility (ABCDE) bundle processes as improving a number of short- and lon

228 gram includes the first large-scale episodic bundling program for bariatric surgery.

229 le medications into an expanded ESKD payment bundle prompted concerns that dialysis facilities facing

230 simple and highly conserved four-alpha-helix bundle protein that acts as an intracellular transporter

231 R protein family, is a newly identified hair bundle protein that is localized to the tips of the shor

232 Villin is a major actin-bundling protein that assembles the brush border of inte

233 Fascin is an F-actin-bundling protein that plays a key role in stabilizing fi

234 cate dynamin as a unique multifilament actin-bundling protein that regulates the dynamics and mechani

235 ne in the mosquito (Ae-Forked; a known actin-bundling protein) by CRISPR-Cas9 gene editing, we showed

236 rk provides the first evidence for the actin-bundling protein, L-plastin, as a regulator of human MK

237 n, function, and identity of the major actin-bundling proteins in bristles and hairs are known, this

238 ould have wider implications for other actin-bundling proteins that contain a villin-type headpiece d

239 ify T-Plastin, one of the most ancient actin bundling proteins, as an actin stabilizer that promotes

240 affinity, comparable with eukaryotic F-actin-bundling proteins, such as fimbrin.

241 Six1 targets a wide range of hair-bundle regulators and late Six1 deletion disrupts hair-b

242 en conducted but is essential for success in bundled reimbursement models.

243 Conclusions To succeed in emerging bundled reimbursement programs for CABG, hospitals and p

244 al coupling on the motility of the system of bundles remains underdetermined.

245 l transitions within the seven-transmembrane bundle represent the mechanism by which G-protein-couple

246 ing, which enables the generation of F-actin bundles required for the sustained stabilization of high

247 ructure of these active nematics with single-bundle resolution.

248 tested the effects of efference on the hair bundle response to mechanical stimulation.

249 Infections prevented under the cleaning bundle returned a net monetary benefit of AUD$1.02 milli

250 athematical modeling efforts have focused on bundles' rigidity and shape.

251 ogical control parameter for tuning the hair bundle's mechanical sensitivity.

252 d copper protein site within a three helical bundle scaffold which we later revisited and determined

253 is partitioned such that leaf mesophyll and bundle sheath cells accumulate different components of t

254 es in light perception between mesophyll and bundle sheath cells facilitate differential regulation a

255 key C(4) enzymes either to mesophyll (M) or bundle sheath cells is considered a crucial step towards

256 erentially accumulated between mesophyll and bundle sheath cells, indicative of differential network

257 that 61% of all light-induced mesophyll and bundle sheath genes were induced only by blue light or o

258 e MS cell walls adjoining the parenchymatous bundle sheath; and the proportion of leaf GLDP invested

259 mount of concentrated CO(2) that escapes the bundle-sheath cells, for the chilling-tolerant C(4) plan

260 and functional assays to identify the actin-bundling site in FL human villin protein.

261 Despite that, the actin-bundling site in the full-length (FL) villin protein rem

262 in intermediate to its post-fusion 6-helical bundle state.

263 very of mechanoelectrical transduction, hair bundle stiffness, and spontaneous bundle oscillation can

264 action with BVM does not alter the six-helix bundle structure appreciably.

265 ent of fractional anisotropy in the cingulum bundle, superior longitudinal fasciculus, internal capsu

266 ent (ERGIC) membrane, ETM forms a five-helix bundle surrounding a narrow pore.

267 study implemented an environmental cleaning bundle targeting communication, staff training, improved

268 mina folds, and retrograde movement of actin bundles that correlated with nuclear ruptures.

269 They contain actin bundles that dictate their cellular morphology.

270 tral nerve cord produces defasciculated axon bundles that do not reach their targets.

271 ry neurons and Schwann cells form nerve-like bundles that target Merkel cells in organoid hair follic

272 f the prostate adjacent to the neurovascular bundles, the rectum, and the bladder wall.

273 reas CLIK-1 bound to actin filaments without bundling them and antagonized UNC-87-mediated filament b

274 ts that the process is limited by an optimal bundle thickness, which is determined by the electric ch

275 Development of care bundles to enhance recovery after emergency surgeries ma

276 The value of so-called day-case care bundles to reduce high hospital readmission rates with g

277 cellular structures ranging from contractile bundles to the mitotic spindle.

278 the capacity of mechanically sensitive hair bundles to transduce vibrations into electrical signals

279 y cycles of dynamin promote continuous actin bundling to generate mechanically stiff actin super-bund

280 ional team rounds that foster ICU Liberation Bundle use support both care coordination and regular pr

281 a control group (30 patients) with anomalous bundles, ventricular premature beats, atrial flutter, at

282 The same fiber bundle was associated with optimal clinical response in

283 There was an 86% chance that the bundle was cost-effective compared with existing hospita

284 assess whether the implementation of a care bundle was effective in preventing SSI-CRANs.

285 Expansion of the ESKD payment bundle was not associated with increased closure of dial

286 Microtubule bundling was evident in PCa xenografts 2 to 3 days after

287 ter the crime, six thousand dollars in three bundles were found on the shore of the Columbia River ne

288 dults, whether administered alone or as care bundles were included in the analyses.

289 ia can passively form coherent bundles, i.e. bundles which do not contain tangled pairs of filaments,

290 of betaarr1 into the M2R seven-transmembrane bundle, which adopts a conformation similar to that in t

291 control study was used to evaluate the care bundle, which included a preoperative shower with 4% chl

292 ehind the cell body and form a close helical bundle, which propels the cell forward during a "run".

293 structure to form an intermolecular 4-helix bundle with the E6AP AZUL, which is unique to this E3.

294 find that it folds into a compact four-helix bundle with three disulfide bonds.

295 ll the aforementioned logo extensions and is bundled with a companion web application for creating an

296 e constructs were able to form multi-layered bundles with aligned myofibers.

297 isrupt the tip links of individual frog hair bundles with displacement clamping to control hair bundl

298 ding on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembl

299 M exhibited aligned, flat, and compact fiber bundles, with reduced elasticity and organizational comp

300 es at the cell division site, involving FtsZ bundling, Z-ring tethering and membrane reshaping activi