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1 onstration of foreign gene expression in any bunyavirus.
2 of Bunyamwera virus (BUNV), the prototypical bunyavirus.
3 ine encephalitis virus, as well as La Crosse bunyavirus.
4 ver epithelial cells infected by an emerging bunyavirus.
5 may be implicated in the replication of SFTS bunyavirus.
6 T=12 icosahedral organization found for some bunyaviruses.
7 gments are copackaged to generate infectious bunyaviruses.
8 t regulate viral RNA packaging efficiency in bunyaviruses.
9 chment method allowed the discovery of novel bunyaviruses.
10 nts in infected cells, for the first time in bunyaviruses.
11 nce of Lrp1 in cellular infection by diverse bunyaviruses.
12  attractive strategy to rationally attenuate bunyaviruses.
13 ountermeasure development against pathogenic bunyaviruses.
14  Our findings suggest an arthropod origin of bunyaviruses.
15 f heparan sulfate for host cell infection by bunyaviruses.
16 he evolutionary connections that exist among bunyaviruses.
17 al activity against orthomyxoviruses but not bunyaviruses.
18 uture antiviral interventions for pathogenic bunyaviruses.
19 challenged with closely related heterologous bunyaviruses, a similar inhibitory effect was seen.
20                     We propose a model where bunyaviruses activate Wnt-responsive genes to regulate o
21 ly been reported only for Uukuniemi virus, a bunyavirus also within the Phlebovirus genus.
22  the use of LRP1 for viral entry by multiple bunyaviruses also makes LRP1 a promising target for anti
23 R family of receptors for virus entry by the bunyavirus and alphavirus family members.
24            Jamestown Canyon virus (JCV) is a bunyavirus and arbovirus that causes viral neuroinvasive
25 e evaluation of RNAs extracted from selected bunyaviruses and other representative arthropod-borne vi
26 te to advances in research on RVFV and other bunyaviruses and pave the way for the development of nov
27       We discuss the diversity of crustacean bunyaviruses and provide an overview of how these viruse
28  flaviviruses, alphaviruses, picornaviruses, bunyaviruses, and coronaviruses.
29 y holds great promise for the development of bunyavirus antiviral therapies.
30                                              Bunyaviruses are considered to be emerging pathogens fac
31 as well as for vaccine strategies.IMPORTANCE Bunyaviruses are emerging viral pathogens that cause enc
32                                              Bunyaviruses are enveloped negative or ambisense single-
33 eemerging infectious agents such as zoonotic bunyaviruses are of global health concern.
34                                         Some bunyaviruses are transmitted between vertebrate hosts by
35                                              Bunyaviruses are transmitted via a diverse range of arth
36                              The majority of bunyaviruses are vectored by arthropods and thus have th
37 activity against numerous viruses, including bunyaviruses, arenaviruses, paramyxoviruses, coronavirus
38 ion and highlights fusion inhibition against bunyaviruses as a potential contributor to potent antibo
39 ection using flaviviruses, alphaviruses, and bunyaviruses as examples of emerging pathogens of global
40  are shown to be orthomyxoviruses instead of bunyaviruses, as previously thought.
41 tion, which allows mechanistic insights into bunyavirus assembly at near-atomic resolution.
42                          SFTS virus is novel bunyavirus associated with hemorrhagic fever illness.
43 merica, both previously considered potential bunyaviruses based on electron microscopy and physicoche
44 that allows the transmission of vector-borne bunyaviruses between arthropod and vertebrate hosts.
45 in antibodies (VHHs), for the development of bunyavirus biotherapeutics.
46      We have previously shown that the model bunyaviruses Bunyamwera virus (BUNV) and Hazara virus (H
47                            For the prototype bunyavirus, Bunyamwera virus (BUNV), only the terminal 1
48 at the closest CCHFV relative is not another bunyavirus but the arenavirus Lassa virus instead, sugge
49 of the same host cell by two closely related bunyaviruses can, in theory, result in eight progeny vir
50 emorrhagic fever virus (CCHFV), a tick-borne bunyavirus, can cause a life-threatening hemorrhagic syn
51 e provide a detailed description for a novel bunyavirus (Carcinus maenas Portunibunyavirus 1) infecti
52 filoviruses, flaviviruses, arenaviruses, and bunyaviruses, cause hemorrhagic fevers.
53 s (RVFV), an emerging arboviral and zoonotic bunyavirus, causes severe disease in livestock and human
54  RNA viruses such as Orthomyxo-, Arena-, and Bunyaviruses coats the genomic viral RNA and together wi
55 f highly attenuated yet immunogenic chimeric bunyaviruses could be an efficient general method for de
56                                              Bunyaviruses deliver their genome into the host-cell cyt
57 lass for the treatment of potentially lethal bunyavirus disease.
58              Alphaviruses, flaviviruses, and bunyaviruses encode a class II fusion glycoprotein that
59 se findings provide the first description of bunyavirus entry into cells of the central nervous syste
60 nistic understanding of the requirements for bunyavirus entry.
61          Here we show that only vector-borne bunyaviruses express a non-structural protein, NSm, whos
62 d RNA viruses from Ortho-, Filo-, Flavi- and Bunyavirus families, for which there is no FDA-approved
63 ting bunyaviruses place them across multiple bunyavirus families.
64  (RVFV), a mosquito-transmitted virus in the bunyavirus family that causes severe morbidity and morta
65       Members of the California serogroup of bunyaviruses (family Bunyaviridae) are the leading cause
66 ure of the TSWV G(N) is different from other bunyavirus G(N) proteins, they all share similar domain
67             In this study, we found that the bunyavirus Gc glycoprotein is a virulence factor.
68 ical protein with a fold distinct from other bunyavirus genera NPs.
69 viruses from the Alphavirus, Flavivirus, and Bunyavirus genera.
70 que conserved genome termini, as in separate bunyavirus genera.
71 nslated regions (UTR) present at the ends of bunyavirus genome segments are required for essential st
72 tage of the dsRNA panhandle structure of the bunyavirus genome.
73               We define two cardinally novel bunyavirus groups based on live isolation of 26 viral st
74                       The genomes of 2 novel bunyaviruses (>99% complete) in the genera Nairovirus an
75                                              Bunyaviruses have a tripartite negative-sense RNA genome
76                                              Bunyaviruses have a tripartite segmented genome, and inf
77                                              Bunyaviruses have a truly global distribution and can in
78                                              Bunyaviruses have an outer lipid envelope bearing two gl
79           It is not understood why only some bunyaviruses have evolved the capacity to be transmitted
80        Potential pathogens reported included bunyavirus, human herpesvirus 7, and enterovirus D-68, u
81 r the efficient replication of SBV and other bunyaviruses.IMPORTANCE SBV is a newly emerging orthobun
82                 Toscana virus is an emerging bunyavirus in Mediterranean Europe where it accounts for
83                        CCHF virus (CCHFV), a bunyavirus in the Nairovirus genus, is capable of infect
84 nd also a number of related but unclassified bunyaviruses in mosquitoes collected in Zambia.
85                 The high prevalence of these bunyaviruses in sampled Dermacentor ticks suggests that
86  identified as a host entry factor for other bunyaviruses, in mediating JCV infection with a focus on
87 bserved for RVFV, along with other disparate bunyaviruses, indicating a conserved bunyaviral replicat
88 interaction with GAGs is not universal among bunyaviruses, indicating that these viruses, as well as
89 r knowledge of the fundamental mechanisms of bunyavirus infection and provide new avenues for counter
90           To define the role of IRF-5 during bunyavirus infection, we evaluated Oropouche virus (OROV
91  levels and, consequently, the efficiency of bunyavirus infection.
92 nti-viral therapies available to treat human bunyavirus infections and so development of new anti-vir
93 sit that polyamines are required to maintain bunyavirus infectivity and that polyamine depletion resu
94  Severe fever with thrombocytopenia syndrome bunyavirus is a newly discovered bunyavirus with high pa
95                             The diversity of bunyaviruses is still expanding and studies on this will
96                  The L protein of arena- and bunyaviruses is structurally and functionally related to
97           La Crosse virus (LACV), a zoonotic Bunyavirus, is a major cause of pediatric viral encephal
98  IMPORTANCE Rift Valley fever phlebovirus, a bunyavirus, is a mosquito-borne, segmented RNA virus tha
99 characterization of emergent arthropod-borne bunyavirus isolates of medical import as well as related
100                                          For bunyaviruses, it has been well documented that the nonst
101                       Here, we show that the bunyavirus La Crosse virus uses a cholesterol-dependent
102     For the orthomyxovirus influenza and the bunyavirus La Crosse, the 5' end of the genomic RNA bind
103 r results were found using distantly related bunyaviruses La Crosse virus and California encephalitis
104 important to initiate infection by two other bunyaviruses, La Crosse virus and Rift Valley fever viru
105                 In addition, some well-known bunyaviruses like Rift Valley fever and Crimean-Congo ha
106               To multiply and cause disease, bunyaviruses must translocate their genomes from outside
107  channel dependence was identified for other bunyaviruses namely Schmallenberg virus (Orthobunyavirus
108 imilarity to distinct RNA viruses, including bunyaviruses, narnaviruses, and sobemoviruses.
109  response in peripheral organs that controls bunyavirus neuroinvasion in mice.
110 RNA encapsidation and protection function of bunyavirus NP, but also highlights the need for dynamic
111           Independent of caspase activation, Bunyavirus NSs proteins also share with Reaper the abili
112                                        Thus, bunyavirus NSs proteins have multiple Reaper-like functi
113 rast to reports that Bunyamwera virus (genus Bunyavirus) NSs protein inhibits viral minigenome RNA sy
114                                          The bunyavirus nucleocapsid protein, N, plays a central role
115 er RT-PCR amplification, DNAs amplified from bunyaviruses of interest were subjected to a novel multi
116 RNAs extracted from quantitated dilutions of bunyaviruses of interest.
117                                         Many bunyaviruses of the Bunyamwera and California serogroups
118 za A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1.
119        Phylogenomics of crustacean-infecting bunyaviruses place them across multiple bunyavirus famil
120 World Health Organization has included three bunyaviruses posing an increasing threat to human health
121 novel multiplex sequencing method to confirm bunyavirus positivity and provide preliminary, species-l
122                 In polyamine-depleted cells, bunyaviruses produce an overabundance of noninfectious p
123 nd strands are packaged as the genome of any bunyavirus remains largely ambiguous.
124                           Here, we evaluated bunyavirus replication, tissue tropism, and cytokine pro
125         To identify host factors involved in bunyavirus replication, we employed genome-wide RNA inte
126  a safe laboratory model to study aspects of bunyavirus replication.
127 TS) is caused by SFTS virus (SFTSV), a novel bunyavirus reported to be endemic in central and northea
128               We have uncovered that diverse bunyaviruses require polyamines for productive infection
129 role of polyamines in the replication of the bunyaviruses Rift Valley fever virus (vaccine strain MP-
130                     The mosquito-transmitted bunyavirus, Rift Valley fever virus (RVFV), is a highly
131 epresents a newly described architecture for bunyavirus RNP assembly, with implications for many othe
132 s (BUNV; genus Orthobunyavirus) is the model bunyavirus, sharing aspects of its molecular and cellula
133  were genetically equidistant from all other bunyaviruses, showing <15% amino acid identity in the Rd
134 our genome segments were identified in eight bunyavirus species.
135 es such as influenza A and Thogoto virus and bunyaviruses such as La Crosse virus.
136 topenia syndrome (SFTS) virus is an emerging bunyavirus that causes a hemorrhagic fever with a high m
137                     RVFV is a mosquito-borne bunyavirus that is endemic to Africa but has demonstrate
138 alley fever virus (RVFV) is a mosquito-borne bunyavirus that is pathogenic to ruminants and humans.
139 hlebovirus (SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009.
140 itive mutations, in the design of attenuated bunyaviruses that could have potential as vaccines.
141 tomato spotted wilt virus (a plant-infecting bunyavirus), the interferon antagonist protein NS1 of in
142                                     In other bunyaviruses, the nonstructural NSs protein encoded by t
143 ion analysis revealed, for the first time in bunyaviruses, the presence of a direct interaction betwe
144                        Using the model plant bunyavirus tomato spotted wilt virus (TSWV), and the mos
145     During maturation of the plant-infecting bunyavirus Tomato spotted wilt, Gc localizes at endoplas
146 d affinity to the panhandles from the genera Bunyavirus, Tospovirus, and Phlebovirus or Nairovirus.
147 mbocytopenia syndrome virus (SFTSV), a novel bunyavirus transmitted by ticks, is often associated wit
148 with arthropods at deep nodes throughout the bunyavirus tree.
149 11SB17, 11SB19 and 11SB23) reveals a typical bunyavirus tri-segmented genome.
150 gested ancient evolutionary divergence, with bunyavirus-typical morphology for FERV (spheres of 60-12
151 ese results highlight a novel means by which bunyaviruses use polyamines for replication and suggest
152  for reactivity with 44 viruses of the genus Bunyavirus, using a reverse transcriptase PCR technique.
153 al glycoprotein (G(N)) that, like with other bunyavirus/vector interactions, serves a role in viral a
154 f Old World and New World alphaviruses and a bunyavirus was reduced in mature compared to immature ne
155 d viral lineage showing strong affinities to bunyaviruses was termed "Leishbunyavirus" (LBV) and judg
156 ated GTPase capable of restricting growth of bunyaviruses, was elevated in the allantoic and amniotic
157       In the present study on mosquito-borne bunyaviruses we employed a broad-spectrum RT-PCR approac
158 al genomes of a novel alphacoronavirus and a bunyavirus were characterized.
159                      OROV is a tri-segmented bunyavirus, which makes generating a reporter virus chal
160 irus (SFTSV) is a tick-borne human-infecting bunyavirus, which utilizes two envelope glycoproteins, G
161 ia syndrome bunyavirus is a newly discovered bunyavirus with high pathogenicity to human.
162                       The ability to inhibit bunyaviruses with existing cholesterol-lowering drugs ma

 
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