ライフサイエンスコーパス: bursting

1 s when these events occur (via short latency bursting).

2 without frequency adaptation, and intrinsic bursting.

3 the rhythm and replaced it by slow unstable bursting.

4 tein-level stochasticity and transcriptional bursting.

5 s by interglomerular synchrony of infra-slow bursting.

6 and the characterization of allele-specific bursting.

7 he cellular properties underlying endogenous bursting.

8 hey play a major role in neuronal firing and bursting.

9 hrough L-type channels during pacemaking and bursting.

10 ted during exponential phase with no sign of bursting.

11 e expression, largely due to transcriptional bursting.

12 aused by the rescue of anx1 anx2 pollen tube bursting.

13 mutants display spontaneous PT and root-hair bursting.

14 -4 h after the induction of action potential bursting.

15 ng neuronal firing at frequencies typical of bursting.

16 wo forms of output: tonic spiking and phasic bursting.

17 k beta synchrony anticipate episodes of beta bursting.

18 ed by unique trial-to-trial patterns of beta-bursting.

19 g phasic spiking, delayed spiking, and tonic bursting.

20 ne regulatory mechanisms and transcriptional bursting.

21 es the size and frequency of transcriptional bursting.

22 is more evident during periods of high beta bursting.

23 ptor blockade destabilizes locomotor-related bursting.

24 at the level of transcriptional reinitiation/bursting.

25 s sufficient to produce alternating rhythmic bursting (0.15-1 Hz) in lumbar flexor motoneurons.

26 In adult SH rats (n = 8), the VR response to bursting (44.6 +/- 3.9%) was not different to tonic (37.

27 and distinguished two populations: sparsely bursting (~80%) and dominantly bursting neurons (~20%).

28 g16A_Stow, the only Ping locus shared by all bursting accessions, and shown here to correlate with hi

29 ful tools for characterizing transcriptional bursting across genes under different environmental cond

30 Moreover, chronic restraint stress induces bursting action potentials in LHb neurons, which are abo

31 While GABAAR or NMDAR were not required for bursting, activation of AMPARs by climbing fibers (CFs)

32 s with wide-spiking pattern showed increased bursting activity along with increased spike timing vari

33 olved in cellular responses such as neuronal bursting activity and cardiac rhythm.

34 potential depolarisation and high-frequency bursting activity at preferred whisker angles.

35 , which explains the pump's contributions to bursting activity based on Na(+) dynamics.

36 ution of the Na(+)/K(+) pump current to such bursting activity has not been well studied.

37 onist bicuculline had a greater influence on bursting activity in complex versus simple cultures.

38 supported by the finding of an increased MN bursting activity in immature SOD1(G93A) spinal cords an

39 methods to show that synchronous infra-slow bursting activity in mitral cells of the mouse accessory

40 is a key determining factor for the onset of bursting activity in mouse ventricular myocytes.

41 y throughout the network as well as a robust bursting activity in the thalamus, which is consistent w

42 T cholinergic axons selectively enhanced the bursting activity of mesolimbic dopamine neurons that we

43 namics of different ionic currents shape the bursting activity of neurons and networks that control m

44 nteracts with the h-current can regulate the bursting activity of neurons and networks.

45 rter, to examine the role of the pump on the bursting activity of oscillator heart interneurons in le

46 aine injection increases the firing rate and bursting activity of VTA dopamine neurons, and that thes

47 or interspike interval variability of phasic bursting activity was affected.

48 osed of a few hundred neurons that alternate bursting activity with silent periods, but the mechanism

49 ons/organoids, we found increased excitatory bursting activity, which could be explained in part by a

50 C-derived networks showed unique patterns of bursting activity.

51 as drastically different from that of bubble-bursting aerosols from the tank experiments-suggesting a

52 However, we discovered that bursting alone cannot quantitatively recapitulate the fo

53 Bursting also differentiated DA neurons in the medial su

54 gthen, whereas in Dendronotus, curare halted bursting altogether.

55 sol generated from freshwater through bubble bursting, analogous to SSA from seawater.

56 TBPH mutants displayed reduced motor neuron bursting and coordination during crawling and restoring

57 n fails to elicit postsynaptic complex-spike bursting and does not induce LTP at ventral SC synapses.

58 The changes in bursting and excitability were related to the altered AD

59 r, called sacculus, to protect the cell from bursting and maintain its cell shape.

60 H neurons contained immunoreactive dopamine: bursting and nonbursting neurons.

61 Oxytocin excited both bursting and nonbursting neurons.

62 Dynorphin-A inhibited both bursting and nonbursting TH neurons by activating kappa

63 MDA receptor in these neurons, which affects bursting and plasticity, abolishes lever pressing for po

64 were dramatically elevated, favoring rebound bursting and seizure generation.

65 works revealed hyperexcitability and altered bursting and synchronicity.

66 sociation with ripples, and showed increased bursting and temporal coactivation during postexperience

67 g revealed that these regulatory strategies (bursting and the time window) respond in different ways

68 s have well-characterized dual firing modes: bursting and tonic spiking.

69 uate the statistical independence of allelic bursting and track changes in the allele-specific expres

70 iption dynamics in vivo (e.g. transcription 'bursting') and may also have practical implications for

71 ransient stuttering, and transient slow-wave bursting) and 4 steady states (non-adapting spiking, per

72 c cortex), reduced IL single-unit firing and bursting, and attenuated IL gamma and theta oscillations

73 activity, examine the origin of spiking and bursting, and determine which channel types are responsi

74 scriptional process emerging from studies of bursting, and how this work contextualizes the relative

75 persistent stuttering, persistent slow-wave bursting, and silence).

76 ivity, boosting synaptic inputs and enabling bursting, and somatic calcium cannels promoting regular

77 t CA1 network oscillations, pyramidal neuron bursting, and spatial information coding in vivo.

78 tensile stress is high and exposes cells to bursting, and that these roles are independent from cell

79 f this is that pacemaking and, even more so, bursting are associated with a larger Ca(2+) entry throu

80 taneous cross-unit synchrony and single-unit bursting are de facto physiological correlates of tinnit

81 chanisms involving pacemakers, inhibition or bursting are problematic and that simplifying assumption

82 ile, the effects of transient stimulation on bursting are unknown.

83 lling and adhesion, migration, and oxidative bursting, are better measured in seconds or minutes than

84 live imaging to record dynamics, we analyze bursting as a function of position within the intact ani

85 therefore feature alongside transcriptional bursting as a source of noise.

86 We furthermore identify beta bursting as being associated with changes in waveform sh

87 Synchrony and bursting, as well as spontaneous firing rate (SFR), corr

88 h-Rinzel (FH-R) model that exhibits elliptic bursting at a fixed set of parameters with a constant in

89 ythmically active during fictive locomotion, bursting at frequencies independent to the ventral root

90 c firing was seen in depolarized regimes and bursting at hyperpolarized membrane potentials.

91 ple effects: (i) increasing excitability and bursting at moderate spike rates but reducing firing at

92 ved ligand RALF34, which induces pollen tube bursting at nanomolar concentrations.

93 showed the expected loss of visually evoked bursting at the same age as wild-type, two days before e

94 ages, both sets of interneurons show intense bursting, at rates up to 300Hz, which is time-locked to

95 divided into regular spiking (RS-L3PNs) and bursting (B-L3PNs) physiological subtypes.

96 an lead to new insights into transcriptional bursting based on measurements of steady-state mRNA/prot

97 y an algorithm for clustering cells by their bursting behavior (Simulated Annealing for Bursty Expres

98 ent cellular ROS increases or effects in MEA bursting behavior at sub-lethal dosages.

99 work into easily achievable states, affected bursting behavior differently than neurons with high mod

100 re likely to be necessary for driving normal bursting behavior in HVC premotor neurons and suggest th

101 ubstantially elevated, and exhibited greater bursting behavior in SYNGAP1 null neurons.

102 s in freely moving male rats, we studied the bursting behavior of 102 subicular principal neurons and

103 ordings in freely moving rats and found that bursting behavior predicts functional differences betwee

104 rved excitatory synapses contributed more to bursting behavior than inhibitory synapses.

105 ynapses onto itself, in driving network-wide bursting behavior.

106 nscription, might be directly related to the bursting behavior.

107 These bursting behaviors were not linked to anatomy: both cell

108 ction potential and [Ca(2+)]i alternans, and bursting behaviors.

109 rom time varying distributions mimicking the bursting behaviour of observed saltatory growth.

110 the cumulative, but recent, history of beta bursting, both locally and across basal ganglia networks

111 the cumulative, but recent, history of beta bursting, both locally and across basal ganglia networks

112 In bursting bubble ionization (BBI), droplet ejection is ac

113 many cells would be damaged by a particular bursting bubble, or more precisely how much volume aroun

114 gational rate distribution associated with a bursting bubble, we introduce the concept of a fragmenta

115 re mainly formed by film drops produced from bursting bubble-cap films, which become enriched with hy

116 contrast, jet drops formed from the base of bursting bubbles are postulated to mainly produce larger

117 ssessing how effectively fluid motion within bursting bubbles at the ocean surface can shear microsco

118 el PMA (mPMA) were produced from seawater by bursting bubbles at two biologically productive and two

119 own dust and sea salt from sea spray through bursting bubbles have been considered the chief mechanis

120 ered in the ocean are breaking waves and the bursting bubbles produced by such waves.

121 al feedback as the source of transcriptional bursting, but a reconciliation of this perspective with

122 expression were induced by action potential bursting, but not by glutamate bath application activati

123 n a discontinuous pattern referred to as RNA bursting, but the mechanisms regulating this process are

124 e former also suppressed synchronous network bursting by a factor of 1.93 (p < 0.05) in comparison to

125 Such phasic bursting by GABA neurons also occurred in WT mice in ass

126 2)O(2) evokes prolonged, afterdischarge-like bursting by gating a nonselective voltage-dependent cati

127 The reciprocal rhythmic bursting by the pGABA and pNon-GABA neurons drove rhythm

128 CAF, a process comparable to transcriptional bursting causing temporary allelic imbalance.

129 cortico-cortical projections, and intrinsic bursting cells (IB), which have subcortical projections.

130 flected in an asymmetric wiring scheme where bursting cells and regular firing cells are recurrently

131 Bursting cells are selectively used to transmit informat

132 Additionally, bursts fired by sparsely bursting cells encoded spatial information better than i

133 Specifically, sparsely bursting cells have lower firing rates and carry more sp

134 In contrast, neither the rarely bursting cells in Layer III, nor the high-frequency burs

135 tional differences: the activity of sparsely bursting cells showed a stronger spatial modulation than

136 at were classically indicated as regular and bursting cells, and showed differences in the extension

137 In most sparsely bursting cells, bursts defined sharper firing fields and

138 s classified as boundary cells were sparsely bursting cells.

139 rry more spatial information than dominantly bursting cells.

140 n subtypes exclusively exist from regular to bursting cells.

141 numerous onto regular firing cells than onto bursting cells.

142 ation, pulsed stimulation induces restricted bursting centered around the hormonal pulse.

143 tem changes its complex dynamics and how the bursting changes to different oscillations with stabilit

144 Bursting cholinergic neurons (Burst-BFCNs) fired synchro

145 of TRN cell types, including state-dependent bursting, contribute to these output dynamics.

146 The gating characteristics (bursting, cooperativity) of the TRPV4 cluster enhance Ca

147 erneurons, including tonic firing or initial bursting discharge, Ih currents, and islet cell morpholo

148 g differentiation accentuate transcriptional bursting due to the crowding effect of chromatin.

149 ow Notch signaling modulates transcriptional bursting during animal development.

150 isingly, each element has a distinct role in bursting during transcriptional activation by gamma-inte

151 based upon RNA hybridisation studies suggest bursting dynamics arise from alternating inactive and pe

152 cted communities, where neurons obey chaotic bursting dynamics.

153 Moreover, the bursting effects occurred only below/at, but not above,

154 ased the amplitude of drug-induced locomotor bursting, effects that were dependent on the presence of

155 on is governed by islet oscillations such as bursting electrical activity and periodic Ca2+ entry in

156 ry gland typically display either spiking or bursting electrical activity, which is related to the le

157 ism, intracellular Ca(2+) concentration, and bursting electrical activity.

158 ons in intracellular Ca(2+) that result from bursting electrical activity.

159 ls did not contain dopamine and did not show bursting electrical activity.

160 elds to explain their observed quiescent and bursting emission, implying that the field strength with

161 ique topology of the AOB network, infra-slow bursting enables integration and binding of multiple che

162 at the surface until the next explosive slug-bursting event.

163 ering promoted the initiation of synchronous bursting events but entailed incomplete network recruitm

164 ngal spores at high humidity may explain the bursting events of new particle formation in Amazonia.

165 g cortex, is a major source of the transient bursting events that are critical for brain maturation.

166 dergoing a cyclical sequence of swelling and bursting events, coupled to the membrane's compositional

167 a marine aerosol generation tank-five bubble-bursting experiments (with contrasting incubation times

168 estigate the elongational rates generated in bursting films within aqueous bubble foams using both la

169 ) is necessary to achieve the high-frequency bursting firing pattern characteristic of both types of

170 oss affects the topology and transcriptional bursting frequencies of genes near boundaries.

171 des and duration but generate very different bursting frequencies, with strong enhancers producing mo

172 sion, suggesting that enhancer regulation of bursting frequency is a key parameter of gene control in

173 rollability significantly affects changes in bursting from autaptic connections.

174 y measurements of microbes ejected by bubble bursting, further supporting the assignment of BioSS mas

175 on, sustention, or termination of the phasic bursting generated in an intrinsic manner without synapt

176 led under the umbrella term 'transcriptional bursting' has received considerable interest.

177 Increased cross-unit synchrony and bursting have been linked to tinnitus in several higher

178 ene regulatory mechanisms on transcriptional bursting have been studied, it remains unclear how morph

179 ontaneous emergence of synchronized periodic bursting in a network of cultured dissociated neurons fr

180 Here, we postulated that bursting in AIIs underlies the initiation of glutamaterg

181 The presence of increased synchrony and bursting in DCN fusiform cells suggests that a neural co

182 The curare-impaired bursting in Dendronotus was also restored by rewiring th

183 ar locomotor network could trigger locomotor bursting in distant thoracic segments through short and

184 sed the amplitude and frequency of intrinsic bursting in inspiratory neurons.

185 ignaling pathway on metazoan transcriptional bursting in its native context.

186 itative analysis, we examine transcriptional bursting in living Drosophila embryos.

187 the M-current, a conductance that modulates bursting in mature AIIs, blocked retinal wave generation

188 i underlies the 24-hour-based rhythms of RBC bursting in mice.

189 densities by 22% or more eliminates rebound bursting in model thalamic reticular nucleus (TRN) neuro

190 inputs frequently reaching the threshold for bursting in most pyramidal cells.

191 s a general model for synchronous infra-slow bursting in neuronal networks.SIGNIFICANCE STATEMENT Inf

192 ossibly these changes contribute to periodic bursting in pyramidal cells, an essential component in t

193 ivity but are critical for the transition to bursting in response to CRH.

194 annel-dependent functions, including rebound bursting in TRN neurons, with potential implications for

195 Increased bursting in vivo properties of these dopamine neurons an

196 odel of supercoiling-induced transcriptional bursting in which the RNA synthesis leads to the buildup

197 Characterization of transcriptional bursting, including the burst size and frequency, has ma

198 y modulated bursting patterns, revealed that bursting increases vascular resistance (VR) more than to

199 romoter elements to modulate transcriptional bursting individually allows combinatorial fine-tuning o

200 hese shells can relieve internal pressure by bursting intermittently, shrinking and re-growing, provi

201 Together, these findings suggest that beta-bursting is a fundamental signature of the motor system,

202 al core promoter elements to transcriptional bursting is not known.

203 oretical analysis shows that transcriptional bursting is observed when both the supercoiling and the

204 This low-frequency bursting is resistant to block of glutamatergic and GABA

205 Therefore, bursting is the single locus illustration of both gene a

206 Interneuronal bursting is time-locked to glutamatergic barrages in the

207 e day and at night and that the frequency of bursting is what is modulated in a circadian fashion.

208 ers from other bacterial systems, and yields bursting kinetics characteristic of eukaryotic systems.

209 ranscription factor with the transcriptional bursting kinetics of the Gal4 target genes GAL3 and GAL1

210 This facilitates translational bursting, liquidation of storage carbohydrates, increase

211 Interestingly, the frequency of network bursting matches the average of the intrinsic frequencie

212 Here we investigate bursting mechanism in live cells by quantitative imaging

213 Bubble bursting mechanisms at the ocean surface create smaller

214 at increased synchronization denoted by beta bursting might compromise information coding capacity in

215 t input current and eta, such as square wave bursting, mixed mode oscillations, and pseudo-plateau po

216 al responses (regular spiking, fast-spiking, bursting, mixed-mode oscillations, etc.) in understandin

217 o fire action potentials in a high-frequency bursting mode and that this is important for peptide tra

218 lustrate these procedures in six examples of bursting model neurons with similar activity but that di

219 te the kinetic parameters of gene expression bursting, namely the rate that genes turn on, the rate t

220 continuous encoding was more prevalent than bursting near movement initiation or termination.

221 neurons exhibit such graded changes without bursting near specific actions.

222 ons: sparsely bursting (~80%) and dominantly bursting neurons (~20%).

223 The same two groups of bursting neurons also emerged when we clustered extracel

224 lastic dendritic spines of the intrinsically bursting neurons and their interaction with hyper-ramifi

225 Our dynamical models of intrinsic theta-bursting neurons demonstrated that experience-independen

226 st to rat, the regular oscillations of mouse bursting neurons depend on a mechanism involving both T-

227 Thus, bursting neurons do not convey value-prediction errors b

228 We did not find a similar class of NW bursting neurons in L2-L4 of mouse V1.

229 Bursting neurons respond to cues that convey predictions

230 Given its properties, this class of NW bursting neurons should be pivotal for the encoding and

231 y we demonstrate that small LNvs (sLNvs) are bursting neurons, and that I(h) is necessary to achieve

232 l modulation than the activity of dominantly bursting neurons.

233 stripe movement is driven by the exchange of bursting nuclei from the posterior to anterior stripe fl

234 Flooding resulting from the bursting of dams formed by landquake events such as rock

235 Here, we demonstrate increased synchrony and bursting of fusiform cell spontaneous firing, which corr

236 mber of abortive infection events, including bursting of ITs and a reduction in the number of nodules

237 T-type Ca(2+) channels in the high-frequency bursting of Re neurons.

238 evers are the consequence of the synchronous bursting of red blood cells (RBCs) on completion of the

239 PG) was necessary and sufficient for osmotic bursting of the cell.

240 ere we analyze the relative contributions to bursting of the individual core promoter elements-CCAAT,

241 e receptive synergid cell and the coincident bursting of the pollen tube inside the ovule to release

242 , the mechanisms at play responsible for the bursting of these films is still in debate.

243 n use populations of rhythmically active or 'bursting' olfactory receptor neurons (bORNs) to extract

244 een explained, the source of transcriptional bursting (one of the most well-known sources of stochast

245 rts that interact to produce stable rhythmic bursting; one part is the primary half-center kernel, an

246 Hippocampal bursting only starts much later, and triggers a marked t

247 ain immunoreactive dopamine, and show either bursting or nonbursting electrical activity.

248 d that lLNvs fire action potentials (APs) in bursting or tonic modes and that the proportion of neuro

249 onsist of intrinsically rhythmically active 'bursting' ORNs (bORNs) in the lobster, Panulirus argus.

250 s characterized by steady reductions of beta-bursting over bilateral sensorimotor sites.

251 ation was signified by increased phasic beta-bursting over fronto-central sites.

252 efore movement initiation and increased beta-bursting over medial frontal areas with movement cancell

253 ANCE STATEMENT The finding of increased beta-bursting over medial frontal cortex with movement cancel

254 ins have heretofore focused on intrinsically bursting "pacemaker" cells operating in conjunction with

255 ects genes exhibiting allelic differences in bursting parameters and genes whose alleles burst non-in

256 st size, but how regulatory elements control bursting parameters remains unclear.

257 Finally, we uncover a striking co-bursting pattern between TSs located at proximal and dis

258 to contribute differentially to the overall bursting pattern of the promoter during basal transcript

259 y, in vitro studies have identified distinct bursting patterns in the subiculum.

260 hancers to perturbation, the transcriptional bursting patterns of enhancers, and the ability of an en

261 thetic chain (L3) with respiratory modulated bursting patterns, revealed that bursting increases vasc

262 membrane conductances necessary to generate bursting, pharmacological activation of the M-current, a

263 rmittent forcing that precedes switching and bursting phenomena.

264 ot its wild-type form, partially rescues the bursting phenotypes of anx1 anx2 PTs and fer root hairs

265 at linked reporter genes exhibit coordinated bursting profiles when regulated by a shared enhancer, c

266 s provide the first description of pacemaker bursting properties in embryonic preBotC neurons and ind

267 daily rhythms in firing event frequency and bursting proportion under light:dark conditions.

268 ynaptic dysfunction to layer V intrinsically bursting pyramidal neurons in the prefrontal cortex of m

269 gmental area (VTA) DA neuronal frequency and bursting rates, decreases GABA frequency, and amplifies

270 motor control, after which sensorimotor beta-bursting re-initiates.

271 ver distinct subsets of neurons that exhibit bursting responses specifically to a chord but neither t

272 tative noncholinergic BF neurons with phasic bursting responses to the go signal were nearly complete

273 Layer III neurons were only sparsely bursting (SB) and had no DAPs.

274 Brief (1 hr) periods of postsynaptic bursting selectively depressed AMPA receptor (R) synapti

275 age data), suggesting that sensorimotor beta-bursting signifies an inhibited motor system, which has

276 These signatures, which we term slow bursting sleep and propagating wave sleep, share commona

277 the lifetime of the SD's high-accessibility (bursting) state and prolongs the time between bursts.

278 prevalent during periods of inactivity while bursting strongly correlates with locomotor output.

279 fy the relationship among oscillatory power, bursting, synchrony, and phase-amplitude coupling, we re

280 as the "hit-and-run" model and transcription bursting that could not be obtained by in vitro biochemi

281 ynamic interplay between TF mobility and RNA bursting that is responsive to stimuli strength, type, m

282 dynamic clamp restored the original rhythmic bursting, thereby affirming the roles of those synapses.

283 sured simultaneously with membrane potential bursting to determine the phase relationships between th

284 Bursting transcription can cause individual cells to rem

285 t repressed in distal dendrites and display "bursting" translation.

286 ely different responses, such as spiking and bursting under different input conditions, thus forming

287 aracterize and visualize how transcriptional bursting varies over time and space.

288 , we could unambiguously distinguish between bursting vesicles, which was only rarely observed (<0.01

289 The number of autapses required to induce bursting was lowered by adding autapses to high degree e

290 Unlike rats, the mechanism underlying bursting was not dependent on gap junctions but required

291 Although transcriptional bursting was originally observed decades ago, only recen

292 Before movement initiation, beta-bursting was prominent at bilateral sensorimotor sites.

293 ide), colonoid permeability was reduced, and bursting was significantly decreased.

294 -range chromatin contacts on transcriptional bursting, we forced an LCR-beta-globin promoter chromati

295 nce of tinnitus, and increased synchrony and bursting were associated with SFR elevation.

296 source of such randomness is transcriptional bursting, which is when periods of active production of

297 ing that larger cells typically display more bursting, while the smallest cells almost always only ex

298 SCALE to analyze genome-wide allele-specific bursting, with adjustment of technical variability.

299 ochastic gene expression and transcriptional bursting, with implications for regulation of pluripoten

300 We analyze transcriptional bursting within a stochastic nonequilibrium model, which