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1                                              Butyrophilin 1A1 (BTN1A1) and xanthine oxidoreductase (X
2                                              Butyrophilin 1a1 (Btn1a1), which is a member of the Ig s
3 ls(4)-recognize a protein complex containing butyrophilin 2A1 (BTN2A1) and BTN3A1 (refs.
4 f phosphoantigens leads to interactions with butyrophilin 2A1 and the subsequent activation of gammad
5                 These experiments identified butyrophilin-2A1 (BTN2A1) as essential to Vgamma9Vdelta2
6 ound that the human and mouse genes encoding butyrophilin-2A2 (BTN2A2) are regulated by the class II
7              We find that a mAb specific for butyrophilin 3 (BTN3)/CD277 Ig superfamily proteins mimi
8 d or TCR Ab and blocked by Src inhibition or butyrophilin 3 isoform A1 (BTN3A1) disruption.
9 cellular B30.2 domain of the immune receptor butyrophilin 3 isoform A1 (BTN3A1).
10    Evidence pointing to a role for the CD277/butyrophilin-3 (BTN3A) molecules in this response led us
11                              Activating anti-butyrophilin 3A (BTN3A) antibodies prime diverse tumor c
12  immune response to viral infections through butyrophilin 3A (BTN3A).
13          Crystal structures of intracellular butyrophilin 3A proteins alone or in complex with the po
14  Human Vgamma9Vdelta2 T cells recognize in a butyrophilin 3A/CD277-dependent way microbial (E)-4-hydr
15    Activation of Vgamma9Vdelta2 T cells with butyrophilin 3A1 (BTN3A1) agonists such as (E)-4-hydroxy
16                                              Butyrophilin 3A1 (BTN3A1) binds small phosphorus-contain
17                                              Butyrophilin 3A1 (BTN3A1) is an integral membrane protei
18 g of pAg via the intracellular domain of the butyrophilin 3A1 (BTN3A1) molecule.
19  activation of Vgamma9Vdelta2 T cells is the butyrophilin 3A1 (BTN3A1) protein that contains an intra
20  iRBCs stained for the phosphoantigen sensor butyrophilin 3A1 (BTN3A1).
21                                          The butyrophilin 3A1 intracellular domain undergoes a confor
22 2 T cell Ag-presenting transmembrane protein butyrophilin 3A1, providing information on critical resi
23 s, which bind to the intracellular domain of butyrophilin 3A1, triggering extracellular interactions
24                                              Butyrophilin-3A1 (BTN3A1), a protein structurally relate
25                                              Butyrophilin, a membrane protein known to bind to XOR, w
26 t a negatively cooperative model of cellular butyrophilin activation.
27 mology to the carboxyl-terminal sequences of butyrophilin and an additional group of zinc finger gene
28 ion of gammadelta T cells can be elicited by butyrophilin and butyrophilin-like molecules that are st
29              Central to adaptate biology are butyrophilins and other gammadelta cell regulators, the
30                   We evaluated the impact on butyrophilin binding of existing and novel ligands using
31 Recent studies have identified heterodimeric butyrophilin (BTN) 2A1 and BTN3A1 as the molecular entit
32  of the B7 family of costimulatory molecules butyrophilin (BTN) 3A1 and BTN2A1.
33 th other milk fat globule proteins including butyrophilin (Btn) and adipophilin (ADPH).
34                                              Butyrophilin (BTN) and butyrophilin-like (BTNL/Btnl) het
35                                              Butyrophilin (BTN) genes encode a set of related protein
36 germline-encoded Vgamma-specific residues by butyrophilin (BTN) or BTN-like (BTNL) proteins that uniq
37                                              Butyrophilin (BTN)-3A and BTN2A1 molecules control the a
38 f phospho-antigen metabolites (pAgs) through Butyrophilin (BTN)-3A1 and BTN2A1 to the Vgamma9Vdelta2
39                   The Ig superfamily protein butyrophilin (BTN)3A1 was shown to be required for preny
40 cell PAg levels are specifically detected by butyrophilin (BTN)3A1, using its intracellular B30.2 dom
41 Vdelta1+Vgamma9- T cell lines to recombinant butyrophilin BTN2A1 and BTN3A1 demonstrated that both Vd
42 mains of BTN3A1 and the structurally similar butyrophilin BTN2A1.
43                              The MHC-encoded butyrophilin, BTN2A1, is a cell surface glycoprotein rel
44                                    The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3
45 lites through binding to the B30.2 domain of butyrophilin BTN3A.
46 sensing depends on the expression of B7-like butyrophilin (BTN3A, CD277) molecules.
47                     Here, we report that the butyrophilin BTN3A1 inhibits tumor-reactive alphabeta T
48 es are sensed by the intracellular domain of butyrophilin BTN3A1(1-4).
49                                              Butyrophilins (Btns) and butyrophilin-like (Btnl) molecu
50                             HMBPP binding to butyrophilin doubled the binding force between a gammade
51 activation by intact iRBCs is independent of butyrophilin expression by the iRBC, and contact with an
52 way, on Vgamma9Vdelta2 TCR signaling, and on butyrophilin expression by Vgamma9Vdelta2 T cells.
53 a2 T cell activation by phosphoantigen-bound butyrophilin, facilitating immunotherapeutic drug design
54                       Several members of the butyrophilin family and the RoRet gene share an exon of
55 mily molecules; however, the function of the butyrophilin family in the immune system has not been de
56 programmed death 1 ligand 2 (PD-L2), and the butyrophilin family member butyrophilin-like 2 (BTNL2) w
57             Butyrophilin-like 2 (BTNL2) is a butyrophilin family member with homology to the B7 costi
58  we characterize an MHC class II gene-linked butyrophilin family member, butyrophilin-like 2 (BTNL2),
59 flammation, and inhibitory members of the B7/butyrophilin family of ligands have evolved to balance t
60                                          The butyrophilin family of proteins shares sequence and stru
61        BTNL2 is thus the first member of the butyrophilin family that regulates T cell activation, wh
62  TCRs likely coevolved with molecules of the butyrophilin family they interact with, whereas the semi
63 d mouse Skint1 and Btnl2, all members of the butyrophilin family, show greater structural and functio
64  colon with particular new insights into the butyrophilin family.
65 y number expansions in the immune modulatory butyrophilin gene family in long-lived species.
66                           The single BTN1A1 (butyrophilin) gene was positioned approximately 25 kb ce
67 es in mouse, with greatest similarity to the butyrophilin genes.
68            We investigated the expression of butyrophilin in eukaryotic cells with a view to determin
69    We found no evidence for soluble forms of butyrophilin in postmicrosomal supernatants.
70                                              Butyrophilin is synthesized from a single sized mRNA in
71 , reveal structure-activity relationships of butyrophilin ligands, and support a negatively cooperati
72 sion of immune signaling molecules including butyrophilin-like (Btnl) 1, Btnl6, H2-T3, and Clec2e tha
73   The DETC repertoire is shaped by Skint1, a butyrophilin-like (Btnl) gene expressed specifically by
74                                              Butyrophilin-like (Btnl) genes are emerging as major epi
75 ssue-protective cells selected by epithelial butyrophilin-like (BTNL) heteromers.
76                     Butyrophilins (Btns) and butyrophilin-like (Btnl) molecules are emerging as novel
77 cytolytic properties and specificity for the butyrophilin-like (BTNL) molecules BTNL3/BTNL8.
78  skin aligned with and depended on Skint1, a butyrophilin-like (BTNL) protein expressed by differenti
79 ltiple butyrophilin molecules and found that butyrophilin-like (BTNL)1 molecule functions to dampen T
80                       Butyrophilin (BTN) and butyrophilin-like (BTNL/Btnl) heteromers are major regul
81                                              Butyrophilin-like 2 (BTNL2) is a butyrophilin family mem
82  (PD-L2), and the butyrophilin family member butyrophilin-like 2 (BTNL2) were also increased.
83 s II gene-linked butyrophilin family member, butyrophilin-like 2 (BTNL2), the mutation of which has b
84  family of immune regulator genes, including butyrophilin-like 2 (BTNL2; OMIM, 606000), which is asso
85 r milk lipid secretion in lactation, whereas butyrophilin-like 2 is a coinhibitor of T cell activatio
86                                              Butyrophilin-like 2 is expressed in patients with UM and
87                  Main Outcomes and Measures: Butyrophilin-like 2 single-nucleotide variants were asso
88                                              Butyrophilin-like 2 variants showed highly variable freq
89                   Conclusions and Relevance: Butyrophilin-like 2, expressed at various levels by UM c
90            An E2A target gene, the predicted butyrophilin-like gene NG9 (BTL-II), was also identified
91 1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, whi
92 of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin
93  T cells can be elicited by butyrophilin and butyrophilin-like molecules that are structurally simila
94                            Here we show that butyrophilin-like protein 2 (BTNL2) is a potent suppress
95 gamma4 and shows dual reactivity to CD1b and butyrophilin-like proteins.
96 the diversification of its beta-defensin and butyrophilin-like repertoires.
97  do not agree with previous suggestions that butyrophilin may exist in cytoplasmic soluble forms, or
98 lts are discussed with reference to the role butyrophilin may play as the principal scaffold for the
99                                         Some butyrophilins mediate complex interactions between antig
100                            Unlike most other butyrophilin members, BTNL2 lacks the prototypical B30.2
101 er of the extended B7 superfamily related to butyrophilin, mimics PAg-induced Vgamma9Vdelta2 T-cell a
102                                              Butyrophilin molecules (commonly contracted to BTN), col
103  study, we performed an analysis on multiple butyrophilin molecules and found that butyrophilin-like
104 tification in an infant formula (IF) matrix: butyrophilin, mucin 1, xanthine dehydrogenase/oxidase, a
105 virus infection was assayed for lactadherin, butyrophilin, mucin, and secretory IgA.
106 between symptom status and concentrations of butyrophilin, mucin, or secretory IgA was found.
107                                          The butyrophilin proteins BTN2A1 and BTN3A1 are part of the
108                                     Although butyrophilin proteins share sequence homology with the B
109                                          The butyrophilin-related protein Btn2a2 was upregulated on m
110 e gene HLA-H, we identified a family of five butyrophilin-related sequences, two genes with structura
111 revealed key features of phosphoantigens and butyrophilins required for gammadelta T cell activation.
112 tiates transmembrane signaling and activates butyrophilin-responsive cells.
113 nd C-terminal domains were used to show that butyrophilin retains a type I topology in plasma membran
114 , solute carrier family 3 member 2 (SLCA32), butyrophilin subfamily 2 member A1 (BTN2A1), katanin reg
115 ctin cell adhesion molecule 2 (NECTIN2), and butyrophilin subfamily 3 member A2 (BTN3A2).
116            Here, we identified human BTN3A3 (butyrophilin subfamily 3 member A3)(2) as a potent inhib
117           Evidence has recently emerged that butyrophilins, which are members of the extended B7 fami
118  a protein most closely related to mammalian butyrophilins, which are members of the immunoglobulin p
119 t the centre of the interface and gluing the butyrophilins with distinct affinities.
120 pid metabolism (n = 13, 59.10%) and included butyrophilin, xanthine dehydrogenase/oxidase, and lipid

 
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