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5 regulate EGFR-dependent Delta transcription by antagonizing a repressor function of Suppressor of Ha
6 that puc modulates gene expression responses by antagonizing a Rho GTPase signal transduction pathway
7 1p exerts its effect on the RAS/cAMP pathway by antagonizing a ubiquitin-mediated process, excess ubi
8 that stablizes several nutrient transporters by antagonizing a ubiquitin-mediated protein degradation
9 ng histone deacetylase 3 to DNA-bound GR and by antagonizing acetylation of histone H3 and H4 induced
11 ate, not by repressing AG transcription, but by antagonizing AG activity in the center of the flower.
12 by moving alphavbeta3 to the cell front, but by antagonizing alpha5beta1 recycling, which, in turn, i
13 ctor 2, indicating that K1L and C7L function by antagonizing an IFN effector(s) but with a mechanism
19 binding with Msp2 monoclonal antibodies and by antagonizing binding and propagation with recombinant
20 corticoid action in target tissues, possibly by antagonizing biological actions of diurnally fluctuat
21 represses differentiation inhibitory signals by antagonizing BMP receptor-activated Smad activity whi
22 h may promote the generation of interneurons by antagonizing BMP, but may not be required directly fo
24 tially, by altering protein degradation, and by antagonizing BR-induced changes in microtubule organi
25 eriments, we show here that SerRS intervenes by antagonizing c-Myc, the major transcription factor pr
28 2A) antagonist in vivo is greatly attenuated by antagonizing cannabinoid CB(1) receptor signaling or
29 y and, in A431 cells, reduced VDR expression by antagonizing CCAAT enhancer binding protein-beta tran
31 hatase Clp1p/Flp1p regulates G2/M transition by antagonizing CDK activity and is essential for coordi
32 turn, may promote the activation of the SIN by antagonizing Cdk activity until cytokinesis is comple
33 transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repre
35 t phosphorylation of His358 activates KCa3.1 by antagonizing copper-mediated inhibition of the channe
38 tudies indicate that kinesin-5 works in part by antagonizing cytoplasmic dynein and that these motor-
39 reby inhibit the decay of labile transcripts by antagonizing destabilizing proteins that target these
40 sequence-specific replication termini (Ter) by antagonizing DNA unwinding by the replicative helicas
41 viate the positive symptoms of schizophrenia by antagonizing dopamine D2 receptors expressed by stria
42 The overexpressed WntD inhibits invagination by antagonizing Dorsal nuclear localization, as well as
43 ntally induced in healthy human eSCs in situ by antagonizing E-cadherin, combined with transforming g
45 53-dependent cell cycle arrest in G1 and G2, by antagonizing early or late p53-mediated responses, re
46 xperiments demonstrate that BS69 promotes IR by antagonizing EFTUD2 through physical interactions.
51 l for the induction of LTD, possibly in part by antagonizing ERK signaling in hippocampal neurons.
52 BM attenuates tumor cell migratory potential by antagonizing ERK/AKT phosphorylation induced by the c
55 ancers, we show that FBXL16 stabilizes C-MYC by antagonizing FBW7-mediated C-MYC ubiquitination and d
56 positive multiple myeloma xenografts in mice by antagonizing FGFR3 signaling and eliciting antibody-d
60 SC subpopulations in a heterogeneous mixture by antagonizing formation of the chromatin modifier PRC2
61 f the IL-7 receptor alpha-chain (IL-7Ralpha) by antagonizing Foxo1 and negatively regulated signaling
63 and has been proposed to promote wakefulness by antagonizing function of the adenosine A2A receptor.
65 responses to skin cooling and were reversed by antagonizing GABA(A) receptors in the medial preoptic
67 repression in effector CD8 T cells and acted by antagonizing GABPalpha binding and recruiting histone
68 oocyte growth and meiotic maturation in part by antagonizing gap-junctional communication between she
71 LPA) regulates hepatocyte glucose production by antagonizing glucagon-induced expression of the gluco
72 ) hampers neutrophil expansion and migration by antagonizing granulocyte colony-stimulating factor (G
73 A-P plays a central role in cydAB regulation by antagonizing H-NS repression of cydAB transcription w
74 g in fibroblasts suppresses tumor metastasis by antagonizing HGF/c-Met signaling within tumor epithel
76 cancers, sensitize cells to PARP inhibition by antagonizing histone demethylation and obscuring epig
78 dicate that H4K20me3 invokes gene repression by antagonizing hMOF-mediated H4K16Ac and suggest that o
79 del whereby JMJD2A regulates DNA replication by antagonizing HP1gamma and controlling chromatin acces
80 ns as a switch for beta1 integrin activation by antagonizing ICAP1 (Integrin Cytoplasmic Associated P
81 ns as a switch for beta1 integrin activation by antagonizing ICAP1-mediated inhibition of integrin ac
82 opic budding from the WD or the ureter stalk by antagonizing inductive signals from the metanephric m
83 at TRE might exert beneficial effects in PPH by antagonizing inflammatory cytokine production in the
84 , critical regulators of cell death function by antagonizing Inhibitor of Apoptosis Proteins (IAPs),
85 te meiotic maturation, which it does in part by antagonizing inhibitory sheath/oocyte gap-junctional
86 ligase activities of TRAF6, TRAF2, and cIAP1 by antagonizing interactions with the E2 ubiquitin conju
87 le E3L is known to support viral replication by antagonizing interferon (IFN) effectors, including PK
89 (hyaA) expression under anaerobic conditions by antagonizing IscR binding at P(hyaA), since IscR repr
90 that SWI/SNF controls transcriptional memory by antagonizing ISWI-like chromatin remodeling enzymes.
91 2A-B55beta promotes cyclin E1 overexpression by antagonizing its degradation and its inhibition could
94 ARF tumor suppressor protein stabilizes p53 by antagonizing its negative regulator, Mdm2 (Hdm2 in hu
96 rgin, which raises intracellular Ca2+ levels by antagonizing its sequestration, induced immunophenoty
97 the chick) allows sensory organ segregation by antagonizing lateral induction and promoting commitme
98 tumor suppressor that controls proliferation by antagonizing LEF1/beta-catenin-mediated transcription
99 vide a novel avenue to bone anabolic therapy by antagonizing LRP4 sclerostin facilitator function.
102 vel regulator of MT stability that functions by antagonizing mDia1 activity toward actin filaments an
106 P inhibits zinc-dependent induction of Dnmt1 by antagonizing metal-responsive transcription factor-1
108 nstatement by mGluR2/3 blockade was reversed by antagonizing mGluR5, but reinstated sucrose seeking i
111 /N can cause either an apparent hyperalgesia by antagonizing mu opioid-induced analgesia or a net ana
113 ine-rich proteoglycan, inhibits tumor growth by antagonizing multiple receptor tyrosine kinases inclu
114 ssing the c-myc gene P2 promoter, as well as by antagonizing Myc-dependent transactivation through E-
115 activity maintains the prometaphase spindle by antagonizing Ncd and another unknown force-generator
116 IL-4 obliterates osteoclast differentiation by antagonizing NF-kappaB activation in a STAT6-dependen
119 IPergic electrical field-induced relaxation (by antagonizing nitric oxide synthesis or receptor inter
122 tivating Prospero to limit proliferation and by antagonizing Notch signaling to prevent dedifferentia
124 gulates Flo11-dependent developmental events by antagonizing Nrg-mediated repression of the FLO11 gen
125 indicates that Snf1-Gal83 affects adherence by antagonizing Nrg1- and Nrg2-mediated repression of th
126 The ability to control premature delivery by antagonizing or silencing the ECE-1/ET-1 system offer
127 To determine if Chx10 regulates cell number by antagonizing p27(Kip1) activity, we generated Chx10,
128 egulator of the p53 tumor suppressor protein by antagonizing p53 transactivation activity and targeti
129 Wip1) promotes recovery in G2-arrested cells by antagonizing p53, it is dispensable for recovery from
131 stage targeted in ABC-DLBCL transformation--by antagonizing pathways distinctive of GCB-DLBCL, inclu
132 capable of disrupting the PD-1/PD-L1 complex by antagonizing PD-L1 and, therefore, restores activatio
134 ll growth, proliferation, and cell migration by antagonizing phosphatidylinositol 3-kinase (PI3K).
137 cts as a tumor suppressor, at least in part, by antagonizing phosphoinositide 3-kinase (PI3K)/Akt sig
139 demonstrate that AHLs repress petiole growth by antagonizing PIF-mediated transcriptional activation
141 ma is that inhibition of vascular thrombosis by antagonizing platelet integrin alphaIIbbeta3 cannot b
144 y DR3 signaling, suggesting that this occurs by antagonizing pro-apoptotic signals induced by TNF.
145 nterventional approach to inhibit cell death by antagonizing proapoptotic Bcl-2 family members that r
146 ammatory reactions and prevents autoimmunity by antagonizing proinflammatory transcriptional activiti
147 that SLX4IP favors SMX-dependent resolution by antagonizing promiscuous BLM activity during ALT reco
148 gonists from neurons in nociceptive networks by antagonizing putative presynaptic inhibitory opioid a
149 gastrulation, Hh switches to a negative role by antagonizing RA-mediated specification of the endocri
151 2-79, modulate KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the co
152 e and lifetime of SUMO-conjugated substrates by antagonizing reactions catalyzed by SUMO-conjugating
153 rs specifically within Ras-mutant cell lines by antagonizing release of negative feedback signalling,
154 s(36) is to promote transcription elongation by antagonizing repressive Lys(36) methylation by Set2.
155 target gene, p21 (also known as Cdkn1a), or by antagonizing reprogramming-induced apoptosis in mouse
159 s to reach and cross the spinal cord midline by antagonizing Robo1/2-mediated repulsion from midline-
161 th in physiological conditions and in stress by antagonizing SA-dependent growth inhibition through U
162 URX neurons seems to suppress social feeding by antagonizing signalling through a cyclic GMP-gated io
163 e hair colour and body weight, respectively, by antagonizing signalling through melanocortin receptor
166 sults suggest that MIM promotes ciliogenesis by antagonizing Src-dependent phosphorylation of Cortact
167 ed SOCS proteins enhance SREBP-1c expression by antagonizing STAT3-mediated inhibition of SREBP-1c pr
171 ty functions to maintain euchromatic regions by antagonizing Su(var)3-9-mediated heterochromatization
172 berus/Dan gene family, which induces targets by antagonizing symmetrically expressed BMP signals.
175 specification in the second heart precursors by antagonizing Tbx1/10-mediated inhibition of GATAa and
176 performance in adult females was unaffected by antagonizing testosterone in utero, i.e., stress stil
178 hat 9-cis-RA possesses anti-fibrotic ability by antagonizing TGF-beta1 in mesangial cells and that 9-
180 e apoptotic effect of BAD in primary neurons by antagonizing the ability of growth factors to inhibit
183 r role in the elimination of class I-IV NFRs by antagonizing the action of RSC, a remodeling complex
184 arrests replication forks in a polar fashion by antagonizing the action of the replicative helicase (
186 n may play a negative role in cell migration by antagonizing the actions of Rac on cytoskeletal organ
187 could be involved in follicular development by antagonizing the actions of theca cell-derived BMPs.
188 ens the activation of inflammatory responses by antagonizing the activation of the NF-kappaB canonica
189 PPAR-gamma inhibits gene expression in part by antagonizing the activities of the transcription fact
191 actor gene expression independently of Notch by antagonizing the activity of hypoxia-inducible factor
194 with this, Sufu regulates Gli protein levels by antagonizing the activity of Spop, a conserved Gli-de
196 ecifies and patterns the hindbrain territory by antagonizing the activity of the spinal cord specific
197 of lipid disorders, such as atherosclerosis, by antagonizing the agonistic action of endogenous LXR l
199 tated NK cell proliferation during infection by antagonizing the anti-proliferative factor Blimp-1 (P
200 1 susceptibility protein (BRCA1) promotes HR by antagonizing the anti-resection factor TP53-binding p
201 protein CED-9 prevents programmed cell death by antagonizing the Apaf-1-like cell-death activator CED
204 plakoglobin regulates nuclear transcription by antagonizing the binding of beta-catenin to TCF/LEF p
206 gulate microtubule plus-end assembly in part by antagonizing the catastrophe-promoting function of ki
207 ant, prevent the 2-AG-induced cell migration by antagonizing the CB2 and abnormal-cannabidiol-sensiti
208 abilizes acetylated cohesin complexes on DNA by antagonizing the cohesin release factor Wings-apart l
209 S. cristatus, may be beneficial to the host by antagonizing the colonization and accumulation of per
210 f HIF1alpha/VEGF-mediated tumor angiogenesis by antagonizing the crosstalk between PTMs involving HIF
211 s, this restriction was partially surmounted by antagonizing the DNA-dependent protein kinase (DNA-PK
212 ry of hemogenic vascular niche specification by antagonizing the dorsal-ventral regulatory limits of
213 nregulates the Na(+)-Cl(-) cotransporter NCC by antagonizing the effect of full-length WNK1 when expr
214 ry effect over the T-helper 2 (Th2) response by antagonizing the effect of IL-4 on CD4(+) T cells and
215 od vessel formation in the developing embryo by antagonizing the effects of Ang1 and Tie2 and was thu
216 otes the expression of floral homeotic genes by antagonizing the effects of DELLA proteins, thereby a
217 e that RACK1 is a repressor of E1A, possibly by antagonizing the effects of E1A on host gene transcri
218 oxidants may attenuate vascular inflammation by antagonizing the effects of intracellular reactive ox
220 ould function in a dominant-negative fashion by antagonizing the endogenous activity of GSK3beta and
221 in repressing the formation of the organizer by antagonizing the expression of genes involved in orga
223 tes the equilibrium of splice site selection by antagonizing the facilitatory activity of MBNL1 and M
225 inducing apoptosis in whole cells, possibly by antagonizing the function of Bcl-2-related death supp
229 ly blocked the differentiation of TH17 cells by antagonizing the function of transcription factor ROR
232 EGL-4 and KIN-29 regulate CR gene expression by antagonizing the gene repression functions of the cla
233 g food restriction causes growth attenuation by antagonizing the GH stimulatory effects on chondrogen
234 onstrated that SUFU stabilizes Glis3 in part by antagonizing the Glis3 association with a Cullin 3-ba
235 uggesting that HilA promotes SPI4 expression by antagonizing the global transcriptional silencer H-NS
236 sed reversion to a less aggressive phenotype by antagonizing the growth effect of 17beta-estradiol.
237 ) and other AHLs restrict petiole elongation by antagonizing the growth-promoting PHYTOCHROME-INTERAC
238 Recently, anti-inflammatory effects in AD by antagonizing the histamine (H)-4 receptor have also b
241 sential role in enhancing virion infectivity by antagonizing the host restriction molecule SERINC5.
242 that increases chloride secretion indirectly by antagonizing the inhibition of chloride secretion by
243 gh level of INS-7 from URX disrupts learning by antagonizing the insulin receptor-like homolog DAF-2
244 n which the modulation of TRPV1 is inhibited by antagonizing the interaction between TRPV1 and A kina
245 h the inhibition of TF transfer to platelets by antagonizing the interaction CD15 with P-selectin and
246 eant local anesthetics inhibit GIRK channels by antagonizing the interaction of PIP(2) with the chann
247 cocorticoids stimulate C3 subunit expression by antagonizing the interaction of this NF-kappaB protei
248 nC controls the scaffolding function of FtsZ by antagonizing the mechanical integrity of FtsZ structu
249 ding a skin peptide that modifies coat color by antagonizing the melanocyte-stimulating hormone recep
250 s tumor suppressive function in the pancreas by antagonizing the metaplastic conversion of acinar cel
254 osome 10 (PTEN) is a lipid phosphatase that, by antagonizing the phosphoinositol 3-kinase (PI3K) path
255 avoidance responses in Arabidopsis thaliana by antagonizing the phytohormones auxin and gibberellin.
256 PTEN helps regulate cellular chemotaxis by antagonizing the PI3K signaling pathway through depho
258 hat Sema-PlxnD1 signaling exerts this effect by antagonizing the proangiogenic activity of vascular e
263 fork protection complex is essential for PFA by antagonizing the Rrm3 helicase that displaces nonhist
264 supports VACV replication in mammalian cells by antagonizing the same antiviral factor(s) that is ind
265 F secretion, and thereby cell specification, by antagonizing the Senseless transcription factor in th
267 uggest that T(H)1 cells may mitigate uveitis by antagonizing the T(H)17 phenotype through the IFN-gam
270 ritical switch that prevents their apoptosis by antagonizing the trans-activation of puma by p53.
271 2 may inhibit E1A induced cell proliferation by antagonizing the transcriptional activation function
272 promotes the expression of vulval cell fates by antagonizing the transcriptional and chromatin-remode
273 alignant properties of human carcinoma cells by antagonizing the tumor-promoting activity of TGF-beta
274 evelopment of lethal cancer at least in part by antagonizing the tumor-suppressive functions of the S
275 rferes with the base-excision repair pathway by antagonizing the uracil DNA glycosylase (Ung2) enzyme
278 ity of targeting the stability of tankyrases by antagonizing their interaction with USP25 to modulate
282 ns cooperatively facilitate KLF14 expression by antagonizing this multisubunit repressor complex in E
285 ilitate expression of these cell cycle genes by antagonizing transcriptional repression mediated by p
286 lex overactivity can be partially normalized by antagonizing TRPv1 receptors in skeletal muscle.
287 sensing dependent upon cGAS-STING.IMPORTANCE By antagonizing type I interferon production and action,
289 cantly reduced LMP, suggesting that DHA acts by antagonizing upstream signals leading to lysosomal dy
290 ogenic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor recep
291 placenta causes pre-eclampsia-like features by antagonizing vascular endothelial growth factor signa
292 a prominent role in the VEGF receptor system by antagonizing VEGF receptor signaling by acting as a d
293 production of runx1+ HSPCs in the AGM region by antagonizing VEGF signaling and subsequent assignment
297 that Scc1 sumoylation by Mms21 promotes SCR by antagonizing Wapl at a step after cohesin loading at
298 EGFR signaling directs cells to become notum by antagonizing wing development and by activating notum