ライフサイエンスコーパス: by itself

1 retroviruses and produce cell transformation by itself.

2 te kidney injury-like neutrophil dysfunction by itself.

3 nched conformation in response to pH changes by itself.

4 ystem allowed monitoring the effects of Hog1 by itself.

5 not account for the reduction in firing rate by itself.

6 cTBS with 150 pulses (cTBS150) has no effect by itself.

7 by a subsequent protocol that has no effect by itself.

8 D supports NA assembly, the TMD was examined by itself.

9 Turbulent shear does not boost settlement by itself.

10 random clusters for systems of whey protein by itself.

11 triction of HIV-1 than either function would by itself.

12 n, protein binding of the drug, and the drug by itself.

13 beta toxicity, without inducing any toxicity by itself.

14 atic function, whereas maize ISA1 was active by itself.

15 ing was observed in the case of CBPQT(2(*+)) by itself.

16 ceiving stimulation too weak to induce L-LTP by itself.

17 on under conditions where CCL27 is monomeric by itself.

18 n no aberrant in vitro or in vivo phenotypes by itself.

19 ither recombinant LiGPPS subunits was active by itself.

20 cyclization/demethylation reaction sequence by itself.

21 tor that has no cocaine-like abuse potential by itself.

22 not show any effect on origami conformation by itself.

23 m this function, exogenous phosphatidic acid by itself (300 pM) increases GTP binding and enhances PL

24 bition of olfactory sensory neurons elicited by itself a full range of olfactory behaviors from attra

25 Data also suggest that SMN-C1 can induce by itself a limited terminal sprouting response in SMA a

26 AS and suggest that a fall in CK flux is not by itself a necessary cause of transition to systolic fa

27 tion could be detected between E1p and E2pCD by itself, a domain-induced interaction was identified o

28 D reorientation may be important, it is not, by itself, a sufficient condition for G stimulation.

29 g that reduction of miR-H6 expression is not by itself able to alter the establishment of latency for

30 e show that the secretome of cancer cells is by itself able to induce collagen linearization independ

31 eover, overexpression of SIRT6 in astrocytes by itself abrogates the neurotoxic phenotype of ALS astr

32 ic agents in peripheral nerve tissues cannot by itself account for their associated neurotoxicity.

33 Although it had no effect by itself, acetaminophen greatly increased the reflex ir

34 his is the first demonstration that nicotine by itself affects responses in the human retina.

35 oma therapy, but is likely to be ineffective by itself against advanced cancer.

36 , however, treatment with doxorubicin, which by itself also induced autophagy, markedly reduced the e

37 (Met-818) and GluN2A(Leu-824), that does not by itself alter ethanol sensitivity, whereas a previousl

38 that the S segment of the same virus confers by itself an attenuated phenotype to wild-type SBV, as i

39 e-threatening condition and it should not be by itself an indication for surgical treatment.

40 edicted treatment response with 64% accuracy by itself and 71% accuracy when combined with baseline c

41 ed to assess the effect of this polymorphism by itself and alongside variants in CYP2C19 on cardiovas

42 d synthesis of these architectures is an art by itself and as such is worth being reviewed.

43 We present here crystal structures of SlyA by itself and bound to a high-affinity DNA operator sequ

44 the N-terminal coiled-coil domain of ANGPTL4 by itself and full-length ANGPTL4 both bound with simila

45 report that resveratrol elevated cAMP levels by itself and further potentiated a forskolin-induced in

46 ngly, CXCL10 expression could be upregulated by itself and IL-17 in inflammatory cells.

47 howed that osteogenic induction medium (OIM) by itself and in combination with Si (25 mug/ml) signifi

48 ne Top1 inhibitor in phase 1 clinical trial, by itself and in combination with the cell-cycle checkpo

49 ent the near-atomic structures of the BBSome by itself and in complex with ARL6(GTP), and we describe

50 scopy structures of CLC-7 in occluded states by itself and in complex with OSTM1, determined at resol

51 lly, PDE8A regulates testosterone production by itself and in concert with additional IBMX-sensitive

52 D23580, and thereby prevents superinfection by itself and other phage that uses the same O-antigen c

53 Co-Black TNTs induce the activation of PMS by itself and stabilized oxygen vacancies that enhance t

54 Sourdough fermentation by itself and with chestnut flour reduced volume of loav

55 C38 is also highly soluble by itself, and it lends its high intrinsic solubility to

56 Intrinsically disordered by itself, and previously uncharacterized, the E6AP-bind

57 es, complicating the use of chiral asymmetry by itself as a definitive biosignature.

58 e for engineering custom specificities, both by itself as a new scaffold alone and in hybrid construc

59 chain can efficiently reach the cell surface by itself as an IgE-binding receptor in the absence of a

60 Thus, 11-cis retinal by itself, as well as other agents that form photosensit

61 tic lesions across multiple data sets and is by itself associated with disease recurrence and disease

62 Fmn2 by itself associates very poorly to filament barbed ends

63 is a distinct pathogenic mechanism that can by itself be effectively targeted for neuroprotection.

64 ut they suggest that such a system would not by itself be sufficient to explain imitation at any age.

65 Our results also show that ScMre11 by itself binds to DSB ends, then promotes end bridging

66 athway not only stimulates the TRPC6 channel by itself but also sensitizes the channels to diacylglyc

67 FliM does not multimerize efficiently by itself but does so in the presence of FliG.

68 ternal stores could not trigger mPTP opening by itself but significantly decreased the CRC.

69 lavour complexes were reported with limonene by itself but were observed when added in binary flavour

70 nable to utilize the proteinaceous substrate by itself, but could grow by using the hydrolysate amino

71 insufficient to activate rhomboid expression by itself, but does so in conjunction with additional fa

72 The probe is almost nonemissive by itself, but it gives turn-on fluorescence in the pres

73 did not affect endocrine cell proliferation by itself, but synergistically enhanced proliferation wh

74 eagent, suggesting that the antibody agonist by itself can elicit maximal activity, a notion that was

75 piratory infection, RIPK3-mediated apoptosis by itself can limit IAV, without need for necroptosis.

76 Our data demonstrate that glucotoxicity by itself can trigger cardiac dysfunction and that a glu

77 Usp14's ubiquitin-like (Ubl) domain, which, by itself, can trigger proteasome activation.

78 trans-Golgi network, although the EXS domain by itself cannot mediate Pi export.

79 of filament assembly in a confined space is by itself capable of yielding the remodeling behavior ob

80 (O-GlcNAc) transferase (OGT), an enzyme that by itself catalyses the addition of O-GlcNAc onto serine

81 response to this treatment, but not rPrP(c) by itself, cause increased chemotaxis of both uninfected

82 Down-regulation of FoxO1 using siRNA by itself caused up-regulation of claudin-5 expression a

83 lular metabolome showed that FLT3 inhibition by itself causes profound alterations in central carbon

84 By itself, CCR8 stimulation was unable to rescue Tregs f

85 By itself, CER will not solve the tension that exists be

86 chemical success without clinical success is by itself clinically important and older women and men c

87 er must be able to persist with the resource by itself, coexistence becomes consistently less likely

88 The FM by itself contains a significant amount of phenolic acid

89 ing and Treg depletion, as neither mechanism by itself could fully rescue the exhaustion phenotype.

90 omic structure of the relevant Nup58 segment by itself, demonstrating that it forms a twofold symmetr

91 LUF7244 treatment by itself did not disturb or rescue wild type (WT) or G6

92 study, we show that the TLR7/8 agonist CL097 by itself did not induce NADPH oxidase activation in hum

93 utation of the identified AKT substrate site by itself did not perturb B cell development.

94 However, they reported that EPCR blockade by itself did not reduce the severity of bleeding in hem

95 Inactivation of Pot1a by itself did not stimulate endometrial carcinogenesis,

96 Notably, however, chloride loading by itself did not trigger full ictal events, even with a

97 03 deletion mutant, although fully competent by itself, did not efficiently infect mice when transmit

98 Foveal ablation, by itself, did not produce systematic alterations in eit

99 s that the loss of the vacuolar Ca(2+) pumps by itself does not cause a catastrophic defect in ion ho

100 d using an amphiphilic block copolymer, that by itself does not form micelles due to its limited hydr

101 y of the "healthy" surrounding tissue, which by itself does not generate seizures, but can support se

102 ng T cells is slow, occurring over 96 h, but by itself does not result in a significant upregulation

103 High SYK expression by itself drives the constitutive activation observed in

104 albumin level is a risk factor for infection by itself (e.g., by being associated with a higher free

105 Whereas desipramine did not by itself elicit circulating HSPCs, it increased G-CSF-t

106 expression of the truncated PR8 NS1 protein by itself enhances the inhibition of the activation of I

107 demonstrate that this truncated NS1 protein by itself enhances this suppression, demonstrating that

108 a and a relatively small sample size cannot, by itself, establish a causal connection between smoking

109 In one condition, the MOT was performed by itself establishing the baseline performance of each

110 nitiate autoimmune or inflammatory pathology by itself, even though every immune cell population had

111 xplain the observed decrease in colonization by itself, even under conservative assumptions for the e

112 self-assembling sequence was not immunogenic by itself, even when delivered in CFA.

113 se of the overall abundance of TonEBP/OREBP, by itself, eventually raises its effective level in the

114 esponded to a gain of function: whereas CTA1 by itself exhibited minimal in vitro activity at 37 degr

115 on 57 (previously known; P = 1 x 10(-1,355)) by itself explained 15.2% of the total phenotypic varian

116 to this surge in adoption, but income growth by itself explains most of the increase.

117 However, CeA stimulation by itself failed to support behavioral self-stimulation

118 This peptide, by itself, failed to generate any current when transfect

119 induced Treg induction because Flt3L/antigen by itself fails to induce Treg.

120 However, this model by itself fails to predict the magnitude of enzymes' rat

121 t capable of inducing long-term memory (LTM) by itself, flies develop an LTM.

122 /-) MEFs, and neither receptor was essential by itself for the antiviral response to UK rotavirus.

123 s the full-length (M1) AQP4 isoform does not by itself form OAPs but can coassemble with M23 in OAPs

124 intermediate, capable of emitting dim light by itself, formed from the reaction between guanines of

125 At 37 degrees C, N&PL by itself forms coexisting L(alpha) and L(beta) phases.

126 ing mental representations is not sufficient by itself; gist representations must be connected to val

127 n the other hand, sequencing of the library, by itself, gives information that is mostly unrelated to

128 Second, no data source provides, by itself, global coverage at a suitable temporal recurr

129 development, respectively, whereas nutrition by itself had a small effect size of 0.09.

130 ficantly by application of pooledhIgG, which by itself had no significant effect.

131 The salmon PI, however, by itself had very low oxidation levels.

132 Although CFA, by itself, had little effect on spatial memory, morphine

133 By itself, HAMNO treatment creates DNA replication stres

134 mobilization-induced surge in corticosterone by itself has delayed detrimental effects on amygdalar s

135 t extended to aqueous solution because water by itself has field fluctuations that are too large and

136 uct maytansine, a microtubule inhibitor that by itself has limited clinical activity and high systemi

137 Interestingly, the deacetylase core of Sirt1 by itself has no catalytic activity.

138 ir efficacy, even though one of the two mAbs by itself has no effect on neutralization.

139 Although DOT1L loss by itself has no major defect in transcription elongatio

140 This particular combined approach by itself has not previously been shown to be efficaciou

141 Self-blood pressure monitoring, by itself, has been shown to be an effective tool in pre

142 The R145W RCM mutation by itself, however, does not impact LDA.

143 areG(0) approximately -2 kcal/mol), whereas, by itself, hydrogenation of N2(g) is highly endergonic.

144 By itself, ICOS-L blockade reduced accumulation of intra

145 3 cysteine residue (NS2/C113) when expressed by itself in cells and during infectious-HCV replication

146 Nes-S cannot form filaments by itself in cytoplasmic intermediate filament-free SW13

147 The ROR score was significantly prognostic by itself in years 5 to 10.

148 o not respond to an appetitive US of sucrose by itself, in contrast to their robust response to an av

149 2, although unable to associate with heparin by itself, increased the association rate of the binding

150 uare of the number of possible states, which by itself increases exponentially with the number of sub

151 Nor did CeA stimulation by itself induce any aversive state that motivated escap

152 Within this subset, only NeuroD4 could by itself induce neuronal reprogramming in both mouse an

153 DksA and is only half the size of DksA, TraR by itself inhibits transcription as strongly as DksA and

154 d evidence for abrupt climate changes but is by itself insufficient for quantitative reconstruction o

155 We found that the beta1-subunit can by itself interact with TP and that this association can

156 the protein folds reversibly and reassembles by itself into the knotted dimeric conformation without

157 that the PAR posttranslational modification by itself is a high affinity ligand for XRCC1, requiring

158 GA by itself is a mild antimicrobial and has a pro-oxidant

159 The high-resolution assay revealed that G40P by itself is a very weak helicase that stalls at barrier

160 In mouse xenograft studies, alpha-MT by itself is able to reduce the growth of the ER-positiv

161 rucial to determine whether cocaine exposure by itself is an etiological factor and, if so, to determ

162 llectively, the data indicate that the toxin by itself is capable of crossing epithelial barriers.

163 Nb.F3 by itself is functionally inert, providing a convenient

164 not only miR-22 inhibits BMP-7/6, but miR-22 by itself is induced by BMP-7/6.

165 reduced antigen burden in the chronic phase by itself is insufficient for rescue of exhausted CD8(+)

166 ce or diminution of humoral immune responses by itself is insufficient to drive the R5-to-X4 switch a

167 results suggest that sperm hyperpolarization by itself is key to enabling mice sperm to undergo the a

168 The sensor by itself is nontoxic to cells in culture and has been u

169 However, absence of light by itself is not a sufficient environmental signal for e

170 r, we demonstrate that N-acetylhomotaurinate by itself is not an active psychotropic molecule.

171 elevations in serum EPO, indicating that EPO by itself is not directly involved in Hamp1 regulation.

172 Therefore, myeloid replacement by itself is not likely to be effective as a therapeutic

173 suPAR by itself is not the cause for direct podocyte injury, i

174 PTA by itself is only one of several indices of severity of

175 Temperature by itself is probably not a major determinant in regulat

176 This GAF domain by itself is sufficient for covalent attachment.

177 ved in signal transduction, and this subunit by itself is sufficient to couple extracellular stimuli

178 monstrated here that over-expression of CIB1 by itself is sufficient to drive localisation of SK1 to

179 We show that increased expression of ERG by itself is sufficient to induce expansion of MEPs in f

180 The proapoptotic Bcl-2 protein Bax by itself is sufficient to initiate apoptosis in almost

181 able to function are necessary, and neither by itself is sufficient, for Cx37 to mediate growth supp

182 TPP1/POT1a and RPA indicates that TPP1/POT1a by itself is unlikely to exclude RPA.

183 data suggest that C9orf72 loss-of-function, by itself, is insufficient to cause motor neuron disease

184 activity of Wnt/beta-catenin signaling that, by itself, is known to cause a nearly identical phenotyp

185 ecursor GA12, although biologically inactive by itself, is the major mobile GA signal over long dista

186 silonRI alpha-chain reached the cell surface by itself, it formed a ligand-binding receptor that stab

187 each of these three features is challenging by itself, it is remarkable that the orthogonal QPM supe

188 Although N17 is highly soluble by itself, it lowers the saturation concentration of sol

189 ugh PGE2 does not induce IL-23p19 expression by itself, it synergizes with both extra- and intracellu

190 The R1 subunit has no endonuclease activity by itself; it strongly stimulates REase activity when in

191 Administered by itself, KWAR23 is inert, but given in combination wit

192 Notably, Red1, by itself, lacked DNA-pairing ability; however, it poten

193 Here we show that a male's presence by itself leads to lifelong alterations in life history

194 By itself, loss of NuRD activity is not sufficient for t

195 Addition of a CaP coating to SBAE Ti by itself may affect key events of in vitro osteogenesis

196 ition is a known trigger of ferroptosis that by itself minimally affects AML cells.

197 PMV infection by itself modulated expression of putative genes functio

198 Consequently, PE represents by itself more than half of all plastic wastes.

199 addition to markedly reducing spine density by itself, morphine amplified the effect of higher level

200 In contrast, neither maternal separation by itself nor the rearing-by-drug interaction was signif

201 s of mice is not sufficient to promote ccRCC by itself, nor does it enhance HIF1alphaM3 oncogenesis w

202 fore, potentiometry as a single technique is by itself not sufficient to obtain information about the

203 amate receptor subunit, which decreased p(r) by itself, occluded the interference with postsynaptic N

204 may encroach on surrounding natural forests by itself occurred in China.

205 ne containing peptide building block, which, by itself, only forms trimers and tetramers that do not

206 ed significantly slowed inactivation, either by itself or after equimolar coexpression with the wild-

207 Serum cystatin C, by itself or as a part of an estimated GFR, was a signif

208 The code can be run by itself or as part of a larger simulator.

209 estored when the C terminus was co-expressed by itself or fused to the C terminus of the beta-subunit

210 We also examined whether ANK3, by itself or in a panel with other top CFG-prioritized g

211 KG and identifies cell-permeable aKG, either by itself or in combination with ETC inhibitors, as a po

212 A null mutation in COX25 by itself or in combination with other COX mutations doe

213 expression of oncogenic K-Ras(G12V), either by itself or in combination with RAF dimer promoting inh

214 ted analog peptide NY-ESO-1 157-165V, either by itself or in combination with the pan-DR epitope NY-E

215 niger) did not cause cell wall creep, either by itself or in combination with XEG.

216 e multifactorial uses as a bioactive peptide by itself or in tissue engineering.

217 We introduced ShMKS2 by itself or together with ShMKS1 to Arabidopsis (Arabid

218 action of the E1o-h with 2-oxoglutarate (OG) by itself or when assembled from individual components i

219 f infections than those with either disorder by itself (P < .0001).

220 c-statistic: 0.56 vs. 0.56) although neither by itself performed well.

221 Therefore, alum by itself poorly induces Mo-DCs to migrate to draining L

222 8, was also in the expression signature and, by itself, predicted poor clinical outcome in one cohort

223 al defeat, although not producing depression by itself, produced in 50% of rats reduced threshold for

224 DDK phosphorylation of Mcm2-7 does not by itself promote separation of the double hexamer, but

225 th chondroitinase ABC (denoted ChABC) could, by itself, promote the plasticity of tracts that were sp

226 ecules per envelope glycoprotein complex and by itself promoted HR1 exposure.

227 Thus, neither dPCR platform by itself provides metrologically traceable estimates of

228 The N-terminal RRM domain by itself provides the editing activity of ORRM3.

229 des being a physically meaningful phenomenon by itself, provides a resolution.

230 deled by a single differential equation, can by itself rapidly clear small initial numbers of pneumoc

231 Although overexpression of MYCN by itself rarely caused bone marrow metastasis, combinin

232 sed to constitutively activate GPHR, (b) can by itself rearrange GPHR into a fully active conformatio

233 As expected, the vaccine by itself reduced viral loads but had no acquisition eff

234 both drugs combined, relative to either drug by itself, reduced loss aversion in the absence of an ef

235 s to acute electric footshock stress did not by itself reinstate drug-seeking behavior but potentiate

236 We also found that Msx1 by itself represses transcription from this proximal Bmp

237 ich is more effective than use of either one by itself, requires that any resistant virus have mutati

238 TCAH exposure by itself resulted in a decline in mitochondrial respira

239 We found that IR inactivation by itself resulted in a marked decrease in skin tumorige

240 posure to traumatic stress during deployment by itself resulted in longitudinal increases in SKA2 met

241 c profiles of rILYd4 in mice, we showed that by itself rILYd4 does not adversely mediate in vivo hemo

242 By itself, scar dechanneling rendered noninducibility in

243 However, the prolonged administration of AZA by itself seems to increase HN rate compared with standa

244 creased tendency of STN burst discharges may by itself serve as a direct cause of parkinsonian locomo

245 level of PD-1 expression by T cells does not by itself serve as a reliable marker for immune exhausti

246 The methyltransferase activity of MLL1, by itself severely compromised, is stimulated by the thr

247 Age by itself should not be an absolute contraindication aga

248 Procedure volume by itself should not be used as a proxy measure for surg

249 MP3 rs522616 A was detected, and this allele by itself showed greater promoter activity than the G al

250 we find that although the RIM2 C(2)B domain by itself significantly decreased Ca(2+)-channel inactiv

251 By itself, Sle2 does not induce any autoimmune pathology

252 Inhibition of AR activity by itself stimulated AKR1C3 expression.

253 The antibacterial triclocarban (TCC) by itself stimulates AroB expression only slightly, but

254 s to integrate (from now on called uDNA) can by itself successfully produce infectious offspring viri

255 An EMB grade >/=2R is not by itself sufficient as a basis for clinical decisions o

256 domain that bound most avidly to CHMP4B was by itself sufficient to inhibit the function of ALIX in

257 model-adding a point output nonlinearity-is by itself sufficient to produce cells that are disparity

258 t prolongs action potential duration, is not by itself sufficient to produce EADs.

259 iosynthetic apical sorting of p75 but is not by itself sufficient to reroute a protein to the apical

260 ance of eIF4E interaction with eIF4G was not by itself sufficient to sustain global rates of protein

261 We demonstrate that FOXP1 by itself supports HSPC and leukemic cell growth, thus m

262 N-betaNAC by itself suppressed aggregation of PolyQ-expanded prote

263 Given that (i) B29 administration by itself suppressed disease, (ii) our findings were mad

264 IFN-gamma by itself suppresses MYO18B transcription, but promotes

265 esting that it represents an epigenetic mark by itself that may regulate chromatin structure and tran

266 ation of dynein in live cells indicates that by itself the triple BICD2-N-dynein-dynactin complex is

267 not a significant driver of increment width by itself, the combined effect of tidal movement and tem

268 By itself, the D836A mutation does not confer a phenotyp

269 esent a sort of individual "cardioprinting." By itself, the diagnosis of LVNC does not coincide with

270 Unreactive by itself, the Mo-dimethyl catecholate analogue reduces

271 ugh each of these mutant modifiers is benign by itself, they interact to affect heart development whe

272 By itself, this mechanism only weakly amplifies signalin

273 uggesting that Prdm9 variation does not seem by itself to contribute to equine hybrid sterility.

274 bodies CR6261, F10, and others is sufficient by itself to elicit antibodies with similarly broad anti

275 is a scaling factor necessary and sufficient by itself to induce and maintain secretory cell architec

276 se data suggest that LIT, while insufficient by itself to lead to OB, works synergistically with aspi

277 ed the conformations of integrin in solution by itself to localize the membrane and the talin-binding

278 e by inducing hypothermia, a condition shown by itself to reduce the thrombolytic and proteolytic pro

279 man cancer, MYC deregulation is insufficient by itself to transform cells.

280 main of Ets1 is required, but not sufficient by itself, to block ASC formation.

281 -retention domain (KTEL), and is sufficient, by itself, to promote the acquisition of invasive and me

282 lk and As in organic, none of these elements by itself was able to discriminate between organic and c

283 Resistin by itself was able to induce acute kidney injury-like ne

284 Moreover, recombinant galectin-10 by itself was able to suppress T cell proliferation.

285 ound that although C5aR2 activation with P32 by itself was devoid of any detectable MAPK signaling ac

286 ts own lacked any reinforcement value: laser by itself was never self-stimulated, not even by the sam

287 e inflammation at the baseline biopsy, which by itself was not associated with graft outcomes.

288 itate cocaine locomotor sensitization, which by itself was not associated with greater cocaine taking

289 However, ORE1 accumulation by itself was not sufficient to cause saul1 phenotypes,

290 Although in concentrated solutions TRN-SR2 by itself was predominantly present as a dimer, the TRN-

291 cells from non-asthmatic donors, compression by itself was sufficient to induce inflammatory, late re

292 Forced expression of SMAD7 in beta cells by itself was sufficient to promote beta-cell proliferat

293 expect this peptide to be a strong inhibitor by itself, we foresee that the insights into SHP2 select

294 he formation of calcium phosphate polymorphs by itself, when bound to immobilized type I collagen and

295 Standardization by itself will not be enough--also required are advances

296 It is weakly emissive by itself with its fluorescence quenched by electron tra

297 100% or serve as an excellent anode material by itself with stable cyclability and consistently high

298 SM gives both electrical and optical signals by itself without applying an external power source.

299 We conclude that serological analysis by itself would greatly underestimate the true memory of

300 old' dose of AMPH in healthy subjects, which by itself would not induce clinically significant increa