ライフサイエンスコーパス: by modifying

1 of uncertainty reported in previous studies by modifying (1) the shape of the typical flight path, (

2 omain protein that regulates gene expression by modifying 3D chromatin structure.

3 Here, we extend this capability by modifying a 40 x 18 mum(2) cantilever into one termin

4 We created this tool by modifying a commercial 8-channel pipet using machined

5 as a transcriptional activator or repressor by modifying a diverse set of substrates.

6 ed an optical density measuring device (ODX) by modifying a generic fitness tracker.

7 By modifying a glass surface with two contrasting functi

8 The biosensor was fabricated by modifying a gold electrode with gold nanoparticles (A

9 ctronic structure of the organoboron species by modifying a heteroaromatic component in the conjugate

10 By modifying a highly conserved adenosine A2503 in 23S r

11 dented mechanism of modulating host immunity by modifying a key ubiquitination enzyme by ubiquitin tr

12 giocarcinoma cell line CC-SW-1 was developed by modifying a NeutrAvidin-biotin system.

13 By modifying a previous assay to use recombinant tubulin

14 The heart failure model is derived by modifying a previously validated electrophysiology mo

15 Here we circumvent these problems by modifying a proven, environment-sensitive biosensor f

16 ) for the non-enzymatic detection of glucose by modifying a screen-printed carbon electrode with coba

17 By modifying a spider silk to be conductive and transduc

18 conducting solid electrolyte is demonstrated by modifying a well-known negative photoresist, SU-8, wi

19 n response to surgical sepsis into the mouse by modifying a widely adopted murine intra-abdominal sep

20 hydrogen peroxide, modulate AMPAR transport by modifying activity-dependent calcium signaling.

21 ical fiber portion and Probe 2 is fabricated by modifying Ag film with GO for sensitivity improvement

22 olling internal structure of cell aggregates by modifying aggregation kinetics is a potential strateg

23 By modifying amino-groups, glycation interferes with fol

24 either by gating reward prediction errors or by modifying an implicit representation of motor compete

25 and not fully recognized evolutionary roles by modifying and biasing natural selection.

26 By modifying and calibrating an active vertex model to e

27 prime stems for recovery during rehydration by modifying apoplast pH and increasing sugar concentrat

28 By modifying Arioc's implementation to exploit this GPU

29 We demonstrate that by modifying array synthesis procedures to accommodate t

30 f upper trophic levels are strongly affected by modifying assumptions associated with phytoplankton i

31 ies, we manipulated the whole-tree C balance by modifying atmospheric CO(2) concentrations [CO(2) ] t

32 ted using self-assembled monolayer principle by modifying Au electrode with cysteamine (Cys) and immo

33 logists predicted that parental care evolves by modifying behavioural precursors in the asocial ances

34 By modifying beta-catenin activity, we force cells withi

35 er to determine the content of consciousness by modifying both taste perception and later action.

36 ccounted for most of the correction achieved by modifying both the domain and the interface.

37 us (five out of six) can impact hypertension by modifying BP and renal phenotypes.

38 band structure can be continuously tailored by modifying cadmium content or temperature.

39 By modifying candidate SNPs in transgenic flies, we show

40 sor was developed to detect anticancer drugs by modifying carbon paste electrodes with glutathione-s-

41 a-catenin activation induces EMT progression by modifying cell-cell junctions, and thereby contribute

42 tolerance to allogeneic cell-based therapies by modifying cells to express immune-suppressive molecul

43 DR by promoting inappropriate S phase entry, by modifying cellular DDR factors directly, or by uninte

44 escent cholangiocyte resistance to apoptosis by modifying chromatin and inducing BCL-xL expression.

45 xpression, a master driver of cell stemness, by modifying chromatin architecture at the Sox2 promoter

46 PRC2) plays an essential role in development by modifying chromatin but what this means at a cellular

47 ssory proteins that antagonize transcription by modifying chromatin structure.

48 ugh these problems can be partially overcome by modifying classical theories for colloidal interactio

49 By modifying composition, film structures were varied fr

50 oercion of human primed embryonic stem cells by modifying culture conditions or through transgenic mo

51 t, we standardized the size of cardiospheres by modifying culture conditions.

52 valuate improvements in specificity attained by modifying cycle threshold cutoffs to define screen-po

53 ediate cellular responses to the environment by modifying cysteines of signaling proteins.

54 tissue-borne adaptive immunity over distance by modifying DC functionality through delivery of granul

55 Reducing lung cancer risk by modifying diet is highly desirable.

56 to adapt to similar environmental challenges by modifying different sets of genes.

57 lymorphism (MTHFR 677C>T) may influence risk by modifying DNA methylation.

58 ygenases plays critical roles in development by modifying DNA methylation.

59 ns to tune physical properties in thin films by modifying electronic structure.

60 nterest in combating these diseases not only by modifying energy intake and lifestyle factors, but al

61 tions and developmental processes can evolve by modifying existing genes or creating novel genes.

62 orporating various 3D printed components and by modifying existing light pathways in a typical patch-

63 receptor-induced apoptosis of infected cells by modifying FADD in an irreversible manner.

64 he non-transferable loci might affect lipids by modifying food intake in environments rich in certain

65 g cell functions can be modulated via opsins by modifying fundamental nonlinear optical properties of

66 ormance, and might offer therapeutic benefit by modifying fundamental pathophysiology in pulmonary va

67 er, the in vivo application of this approach by modifying genomic loci is uncommon, partly due to its

68 by altering abiotic conditions or indirectly by modifying habitats, yet few studies have investigated

69 stem regulates the DNA damage response (DDR) by modifying histone H2A at Lys15 (H2AK15ub) and trigger

70 mazonensis inhibits macrophage inflammasomes by modifying histone H3 activation marks on NF-kappaB-as

71 lase that regulates hepatic lipid metabolism by modifying histones and transcription factors.

72 Microbiota regulate intestinal physiology by modifying host gene expression along the length of th

73 y a key role in altering cerebellar learning by modifying how sensorimotor input is represented at th

74 PS derivatives (AMPDs); they are synthesized by modifying hydrophilic PSs with a variety of hydrophob

75 t opportunities for breast cancer prevention by modifying individual estrogen metabolism profiles thr

76 of terrestrial species (e.g. large mammals) by modifying individuals' movement patterns; our work sh

77 ng protein (IGFBP)-1 influences fetal growth by modifying insulin-like growth factor-I (IGF-I) bioava

78 through plant-mediated indirect effects, or by modifying interactions among species.

79 aracterized in two strains of wild-type mice by modifying interphotoreceptor retinoid-binding protein

80 regulates the growth of intestinal organoids by modifying intracellular crowding and elevating Wnt/be

81 Increasing the density of Env by modifying it in various ways has met with limited suc

82 an energy storage function are demonstrated by modifying its counter electrode with a poly (vinylide

83 e possibility to adjust the pH of the sample by modifying its exposure time with the membrane by vary

84 h the virus can adjust viral gene expression by modifying its genome's nucleosomal organization via c

85 nding to Miro1 halts mitochondrial transport by modifying its interaction with kinesin-1 whereas mito

86 y adapts to survive a wide range of assaults by modifying its physiology and establishing a latent tu

87 ular levels of polyP regulates Top1 activity by modifying its polyphosphorylation status.

88 e visible and near-infrared spectral regions by modifying its size, shape and composition.

89 By modifying KinTek Explorer software, we present a new

90 to adapt plants to hot and dry environments by modifying leaf physiology for improved plant sustaina

91 amined ways of reducing their reactogenicity by modifying lipid A, the endotoxic part of LPS, through

92 tion and loss generated leaf shape diversity by modifying local growth patterns during organogenesis.

93 eloped an immunosensor for E. coli detection by modifying low cost commercial microelectrodes with an

94 ia drives variable host type I IFN responses by modifying LPS in a subset of bacteria.

95 s showing stochastic behaviour are developed by modifying market-ready magnetoresistive random-access

96 Genomic variants can alter miRNA regulation by modifying miRNA target sites, and multiple human dise

97 tive effect on human colorectal cancer cells by modifying molecules involved in either cell cycle arr

98 Whether cell tension regulates development by modifying morphogen signaling is less clear.

99 se data provide new insights into how MAP65, by modifying MT mechanical properties, may regulate the

100 se and strong labeling of individual neurons by modifying multiple loci within mouse and zebrafish ge

101 plex metabolic pathways have been engineered by modifying natural pathways and establishing de novo p

102 ly mitigates the endowment effect indirectly by modifying negative affective responses in the context

103 rtificially generating these activity states by modifying neuronal activity increases the reliability

104 matin remodelers regulate chromatin dynamics by modifying nucleosome positions and occupancy.

105 nyltransferases that modulate Notch activity by modifying O-fucose residues on epidermal growth facto

106 easy modulation of the catalytic performance by modifying one of their building blocks and the develo

107 the only way to limit the virus diffusion is by modifying one's lifestyle limiting social life and fo

108 orating some forms of vestibular dysfunction by modifying ongoing primary vestibular input.

109 sion due to a point mutation can be captured by modifying only the model parameters that describe the

110 des guidance to manipulate exciton diffusion by modifying organic cations in layered perovskites.

111 Finally we mimic vascular normalization by modifying parameters, such as vascular and interstiti

112 ned an affinity-based protein release system by modifying PEG hydrogels with affinity peptides specif

113 ges to actin architecture can be made simply by modifying PFN1 availability.

114 Here, we created a unique Polg animal model, by modifying polg within the critical and highly conserv

115 Four p-type polymers were synthesized by modifying poly(bisdodecylquaterthiophene) (PQT12) to

116 orm and assess how the GQD system is tunable by modifying polymer sequence and type.

117 By modifying pressure during UHPLC separation, it was po

118 s and policy options for reducing CVD burden by modifying preventable risk factors.

119 versely impact food quality and human health by modifying proteins.

120 t mice, utilizing biphasic pulses, optimized by modifying pulse conditions.

121 tic variants that alter RBP-RNA interactions by modifying RBP binding motifs within RNA.

122 possibility to modulate their stoichiometry by modifying reaction conditions.

123 tune the regiochemistry to a desired result by modifying reaction conditions.

124 tly in the membrane-interacting loops and/or by modifying residues away from the membrane-interacting

125 ment in vitro and in vivo, can be controlled by modifying, respectively, the hydrogel's elastic modul

126 NAs (sRNAs) control aspects of this coupling by modifying ribosome access or inducing degradation of

127 By modifying rules that govern activity-dependent synapt

128 at temperature influences evolutionary rates by modifying selective pressures rather than through its

129 g a unique strategy for treating the disease by modifying signal transduction pathways with small-mol

130 ring injection is a risk that can be reduced by modifying skin prep and injection practices.

131 fluence plant growth and community structure by modifying soil biota and nutrients.

132 hat augment exposure to abiotic extremes and by modifying species interactions.

133 change drivers can indirectly affect plants by modifying species interactions.

134 g the change to trophic interactions induced by modifying species.

135 y of the urea-fluoride complexes are tunable by modifying substituents on the urea receptor.

136 colonization and dispersal can be inhibited by modifying surface chemistry.

137 Astrocytes interact dynamically with neurons by modifying synaptic activity and plasticity.

138 ght benefit children with movement disorders by modifying synaptic function.

139 e to stable alterations in neuronal function by modifying synaptic structure and function, and highli

140 ped to enable fine-tuning of EWNS properties by modifying synthesis parameters.

141 that (1) saccadic adaptation can be induced by modifying target object size and (2) this gradual cha

142 (99m)Tc-TCP-1 was generated by modifying TCP-1 with succinimidyl-6-hydrazino-nicotin

143 toxicity study of compounds 11a-q shows that by modifying the 6-position of 7-deazapurine ribonucleos

144 us may function to sort actomyosin processes by modifying the actin track affinity for specific myosi

145 ctly by generating DNA damage but indirectly by modifying the activities of DNA repair and genome sta

146 of SuTEx for fragment-based ligand discovery by modifying the adduct group (AG) and LG with functiona

147 version of insulin molecules into aggregates by modifying the aggregation pathway.

148 as enhanced 5-fold by codon optimization and by modifying the amino acid sequence to be identical to

149 0 phosphorylation alters calcium sensitivity by modifying the AQP0-CaM interaction interface, particu

150 ectional wave pattern, which can be diverted by modifying the arrangement of the spinners within the

151 2 cells on top of the MEAs has been achieved by modifying the array with a poly(dimethylsiloxane) cha

152 Leucettine L41 does not act by modifying the autophagic flux of vesicles.

153 We can reproduce the exhaustion signature by modifying the balance of persistent stimulation of T-

154 empted to improve Robusta sensory properties by modifying the beans chemical composition.

155 By modifying the beta-strand "stalk" of BLV1H12 with seq

156 large increase in granule cell excitability by modifying the biophysical properties of Kv4 channels

157 y from carbonate reservoirs can be increased by modifying the brine composition injected during recov

158 s of the reactants and products, rather than by modifying the catalyst.

159 induced volume transition could be modulated by modifying the chromatin compaction state and remodeli

160 By modifying the clutch model equations to incorporate t

161 ctive strategy to constrain the change of pH by modifying the composition of electroporation buffer.

162 e mechanical conditions are often controlled by modifying the composition of the environment, separat

163 the ability of DnaB to interact with primase by modifying the conformation of the NTD of DnaB.

164 atory and inhibitory neurons can be achieved by modifying the connectivity patterns between both type

165 cally regulate DNA damage signaling pathways by modifying the core histones as well as chromatin modi

166 ectric dipole moment which could be adjusted by modifying the crystal symmetry of the microwave absor

167 t rheumatoid arthritis, reduces inflammation by modifying the cytokine pathway.

168 tion present at the maternal fetal interface by modifying the cytokine profile produced by the stroma

169 s may alter the ecological role of herbivory by modifying the defense strategies of plants and thus t

170 domains can enhance the Seebeck coefficient by modifying the density of states and/or providing type

171 reward-based learning mechanisms as well as by modifying the description of the decision problem, bu

172 By modifying the desolvation gas with acid vapor from pr

173 By modifying the desolvation gas with base vapor from tr

174 the plasmonic resonance of the nanostructure by modifying the dielectric constant of the metal.

175 gulate a symmetry transition event in plants by modifying the direction of auxin transport.

176 d are shown to be dynamically reconfigurable by modifying the direction or polarization of impinging

177 ected from restriction endonuclease cleavage by modifying the DNA using a DNA methyltransferase.

178 We then show that this bias can be corrected by modifying the downward momentum flux to the surface.

179 d self-healing behavior can be further tuned by modifying the electrical double layers surrounding th

180 e developed several biosensors configuration by modifying the electrochemical sensor transducer: (a)

181 iosensor performance can be further improved by modifying the electrode surface to enhance electronic

182 kaline stress tolerance in tomato seedlings, by modifying the endogenous Na(+) and K(+) contents, reg

183 dynamics or induce alternative binding modes by modifying the ensemble of accessible conformations.

184 intracellular molecular clock mechanisms or by modifying the environment of neurogenic niches, with

185 By modifying the ester group and thus its susceptibility

186 utionary outcome of social interactions; and by modifying the evolutionarily stable expression of beh

187 d nutrient spatial patterns only indirectly, by modifying the extent of surface water/groundwater exc

188 -mum-thick, 25-mm-long silica film, achieved by modifying the field's spatio-temporal structure.

189 increasing repulsion or reducing attraction by modifying the fluid medium or by using additives.

190 uency patterns of call sequences or melodies by modifying the formants in their own calls, moving out

191 behavior following noxious heat stimulation by modifying the forward-to-reversal behavioral transiti

192 s to obtain follow-up CT scans were computed by modifying the frequency of CT scans with the hazard o

193 reduce the metabolic consequences of obesity by modifying the gut microbiota and preventing metabolic

194 tor cells, thus amplifying liver damage, and by modifying the hepatic cellular and cytokine milieu dr

195 on conduction through the transmembrane pore by modifying the His37-water proton exchange equilibria

196 tide in HMGL46 alters its activity, possibly by modifying the HMGL46 structure.

197 rm carbon accumulation in tropical peatlands by modifying the Holocene Peat Model (HPM), which has be

198 orms may contribute to the development of AD by modifying the homeostasis of ApoE physiological partn

199 n facilitating breast cancer lung metastasis by modifying the immune microenvironment at the metastat

200 paratopes into the human antibody repertoire by modifying the immunoglobulin (Ig) genes of mature B c

201 rts and numerous attempts to improve outcome by modifying the inflammatory response.

202 e strength of the ligand-ligand interactions by modifying the interparticle spacing through changes t

203 ity to fine-tune the target tissue responses by modifying the intracellular trafficking and secretory

204 arying nanoparticle sizes (5, 13, 23 nm) and by modifying the Kd of the bioreceptor using wild-type a

205 cancer effect, we have developed 35 peptides by modifying the lead.

206 Motor fluctuations may be managed by modifying the levodopa dosing regimen or by adding se

207 rectly (by forming NPQ sites) or indirectly (by modifying the LHCII membrane environment).

208 be used to finely tune the lattice symmetry by modifying the local distortions, i.e., octahedral bon

209 ction with the target species can be altered by modifying the local environment of the direct contact

210 nges the diffusive motion of PTCH1, possibly by modifying the membrane microenvironment in which PTCH

211 guidelines for correcting problematic sites by modifying the metal-binding environment and/or redefi

212 sible to engineer the intestinal environment by modifying the microbiota community structure or funct

213 creted PLD2 contributes to tumor development by modifying the microenvironment, making it a possible

214 apted to an obligate intracellular lifestyle by modifying the morphology and content of their cells.

215 2))(1), which has the identical composition, by modifying the nanoarchitecture of the precursor.

216 The nanofiller dispersion can be improved by modifying the nanomaterial (NM) surface or predispers

217 By modifying the nanoparticle surface coverage, which ca

218 obtain highly specific inhibitors of MMP-14 by modifying the natural non-specific broad MMP inhibito

219 nge electron transfer processes can be tuned by modifying the nature of the proton acceptor in concer

220 ingly, the sublattice interactions are tuned by modifying the Ni-O-Re bond angles through Ca doping.

221 AK1-binding proteins 2 and 3 (TAB2 and TAB3) by modifying the Npl4 zinc finger domain through S-adeno

222 ch to solve this often unappreciated problem by modifying the nucleotide sequences of the target mRNA

223 ave frequency can be tuned over a vast range by modifying the operation parameters.

224 mmunoglobulin G (IgG) antibody avidity assay by modifying the Ortho 3.0 HCV enzyme-linked immunoassay

225 sensor that responds to a specific input(s) by modifying the output of a cognate regulator.

226 diketopyrrolopyrroles (DPPs) can be altered by modifying the pendant aryl substituents to the core.

227 Although the preparation of GPAs, either by modifying the pendant groups such as saccharides or b

228 Five different ligands were prepared by modifying the peripheral thioether moiety with naphth

229 ng light through highly scattering materials by modifying the phase profile of the illuminating beam

230 ir photosynthetic metabolism, and indirectly by modifying the physical environment in which they grow

231 treatment of OTS increased the MB adsorption by modifying the physicochemical properties of OTS and s

232 as to improve the original vaccine candidate by modifying the PIV5 vector or by modifying the RSV F a

233 trolling the types of crosslinks rather than by modifying the polymer itself.

234 al properties of CO(2) -based polycarbonates by modifying the polymer's topological structure.

235 er the patient-specific survival probability by modifying the populations of circulating tumour cells

236 By modifying the position of the CH(2)NH(3)(+) group fro

237 inheritance may interact with genetic change by modifying the rate and type of adaptive mutations.

238 polymer with different charge distributions by modifying the ratio of anionic and neutral end groups

239 tected benzylamine derivatives were achieved by modifying the reaction conditions, which presented an

240 st by appropriately choosing the catalyst or by modifying the reaction conditions.

241 of strong near-field coupling, we show that by modifying the rectangular unit cell lengths due to th

242 ironments, plants can adopt escape behaviors by modifying the relative timing of distinct development

243 MAGE oligos for (i) tuning translation rates by modifying the ribosomal binding site, (ii) generating

244 d RSV F expression by codon optimization and by modifying the RSV F amino acid sequence to conform to

245 ne candidate by modifying the PIV5 vector or by modifying the RSV F antigen.

246 roteins in aqueous solutions can be directed by modifying the salt concentration.

247 L concentration and whole-body fat oxidation by modifying the saturation index of circulating and tis

248 By modifying the secondary building units (SBUs) of MOLs

249 By modifying the self-assembly protocol to promote ring

250 Further, by modifying the sensor use from traditional to dynamic

251 By modifying the solidification rate of this material-te

252 ple geometry profoundly affects the dynamics by modifying the spectral segments that represent small

253 aals materials, this control can be achieved by modifying the stacking order through rotation and tra

254 an be modified to analyze other types of RNA by modifying the steps for RNA purification as appropria

255 in changing its electrical gating properties by modifying the strength of the dipole, and (ii) an inc

256 process and a single anneal process, simply by modifying the structural design and/or the anneal tem

257 This is achieved by modifying the structural design of the SiGe strips, w

258 ly control the conferral of epigenetic marks by modifying the structural mechanics of the chromosome.

259 By modifying the structure of the carbanion nucleophile,

260 By modifying the substituents on the 7-amino-5-thio-thia

261 icoid receptor agonists (DAGRs) was achieved by modifying the substitution at C3 from (S)-3-hydroxy t

262 By modifying the substitution pattern on the alkynone su

263 Then, the working electrode was constructed by modifying the surface of the disposable pencil graphi

264 to the transferrin receptor of cancer cells by modifying the surface of the liposome with transferri

265 rane on solid surface at low pH was improved by modifying the surface with a conductive substrate con

266 An amine layer was produced next by modifying the surface with EDAC/NHS followed by react

267 The fibrils are built by modifying the synthetic peptide fragment correspondin

268 study how mycotoxin levels may be influenced by modifying the technological parameters of both whole

269 th Turing's original model, which we explain by modifying the theory to include heterogeneity.

270 ue to create opportunities for enhancing WUE by modifying the trade-off between photosynthesis and tr

271 have marked impacts on posterior eye health by modifying the translaminar pressure gradient across t

272 n exosomes, may promote invasive progression by modifying the tumor microenvironment.

273 The proposed method is realized by modifying the TurboFold II algorithm for prediction o

274 enzymes (DUBs) can regulate these processes by modifying the ubiquitination status of target protein

275 h direct interactions or indirectly, perhaps by modifying the underlying microtubule lattice.

276 emical properties can be drastically altered by modifying the vacuum fluctuations of the electromagne

277 milies were shown by the grape varieties and by modifying the vine growing practices.

278 trate tunability of the negative speed zones by modifying the viscosity of the suspending medium.

279 A binary search is performed by modifying the weight applied to the flux of the bioma

280 eria survive harmful environmental stressors by modifying their outer membrane.

281 to numerous endogenous and exogenous signals by modifying their proliferation and differentiation.

282 to improve the binding affinity of aptamers by modifying their sequences upon their G-quadruplex and

283 RNAs regulate hundreds of target transcripts by modifying their stability and translation on a broad

284 he animals studied affect disease phenotypes by modifying their susceptibility, presentation and resp

285 ting specific dysfunctional mental processes by modifying their underlying neural mechanisms and on a

286 and circuit motifs but form unique networks by modifying these cardinal units.

287 We simulated the data successfully by modifying those parameters of a clock model that are

288 lso affect tissue movement and morphogenesis by modifying tissue tension in surrounding cells.

289 nfiguration of the sensing elements - either by modifying toggle switches and gene networks, or by pr

290 By modifying total canopy leaf area, its vertical profil

291 the low-pH performance of the YGP1 promoter by modifying transcription factor binding sites in its u

292 bda acted as a unique immunomodulatory agent by modifying transcriptional and non-translational neutr

293 A may indirectly alter the biotic conditions by modifying trophic interactions.

294 By modifying v-AuNW electrodes with polyaniline, Na iono

295 , an attempt to optimize hemodynamic outcome by modifying valve size and orientation as well as ascen

296 ercise slows the trajectory of normal ageing by modifying vascular and metabolic risk factors and/or

297 ake of cancer therapeutics at the tumor site by modifying vascular permeability in the tumor to incre

298 By modifying ventricular relaxation properties and the i

299 ures facilitate forgiveness and reduce anger by modifying victims' perceptions of their transgressors

300 uted to controlled release after consumption by modifying vitamin bioaccessibility.