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1 volving G G proteins, adenylate cyclase, and cAMP-dependent protein kinase.
2 lently label a nonactive site residue in the cAMP-dependent protein kinase.
3 ibitors of RAS, EPAC, RAP1, RAF1, ADCY6, and cAMP-dependent protein kinase.
4 the protein kinases Akt and GSK3beta but not cAMP-dependent protein kinase.
5 rominent and was shown to depend on G(s) and cAMP-dependent protein kinase.
6 ctivation of the proapoptotic protein BAD by cAMP-dependent protein kinase.
7 /Ser(67) inhibitor-1 is a poor substrate for cAMP-dependent protein kinase.
8 and docking (D/D) domain of the cyclic AMP (cAMP)-dependent protein kinase.
9 (i) proteins to control the adenylyl cyclase-cAMP dependent protein kinase A (PKA) pathway to regulat
11 tion between cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) and A-kinase anch
12 ion of adenosine 3',5'-cyclic monophosphate (cAMP)-dependent protein kinase A (PKA) is sufficient and
13 In this paper, we report that cyclic AMP (cAMP)-dependent protein kinase A (PKA) promotes acinus f
14 uires cyclic adenosine 3', 5'-monophosphate (cAMP)-dependent protein kinase A (PKA) signaling, raisin
15 at Tregs use cyclic adenosine monophosphate (cAMP)-dependent protein kinase A pathway to inhibit HIV-
17 d to determine the role of PPT intracellular cAMP-dependent protein kinase A (cAMP-PKA) in the regula
21 s of two major components of cAMP signaling, cAMP-dependent protein kinase A (PKA) and adenylate cycl
22 ity is known to depend on phosphorylation by cAMP-dependent protein kinase A (PKA) and CFTR-ATPase ac
23 was found to be differentially modulated by cAMP-dependent protein kinase A (PKA) and exchange prote
24 DA D(1) receptor(D(1)R) signaling, including cAMP-dependent protein kinase A (PKA) and extracellular
25 C1 and PDE4 modulate NDE1 phosphorylation by cAMP-dependent protein kinase A (PKA) and identify a nov
26 vates dopamine D2 autoreceptors to stimulate cAMP-dependent protein kinase A (PKA) and protein kinase
27 3 subunit, which depended on the activity of cAMP-dependent protein kinase A (PKA) and protein kinase
28 regulated through Ser-133 phosphorylation by cAMP-dependent protein kinase A (PKA) and related kinase
29 lpha catalytic subunit and comparable global cAMP-dependent protein kinase A (PKA) enzyme activity.
32 factor that integrates signaling through the cAMP-dependent protein kinase A (PKA) in many eukaryotes
38 endent changes in the activity levels of the cAMP-dependent Protein Kinase A (PKA) on the formation o
39 nt shows elevated expression of genes in the cAMP-dependent protein kinase A (PKA) pathway and PKA ca
44 gnificant role has been ascribed to the cAMP/cAMP-dependent protein kinase A (PKA) signaling pathway
45 KCa3.1 downregulation is mediated by the cAMP-dependent protein kinase A (PKA) signaling pathway.
46 s and liver expression of fasting-responsive cAMP-dependent protein kinase A (PKA) signaling pathways
47 ith both receptors: Binding to CXCR4 induces cAMP-dependent protein kinase A (PKA) signaling, which i
51 on, localization and regulation of different cAMP-dependent protein kinase A (PKA) subunits account f
53 A single molecule of the catalytic domain of cAMP-dependent protein kinase A (PKA) was attached to a
54 phosphorylation was blocked by inhibitors of cAMP-dependent protein kinase A (PKA), an enzyme involve
55 ferentiation requires activation of CREB and cAMP-dependent protein kinase A (PKA), but the role of P
58 on of Ksp1 is partially activated by the Ras/cAMP-dependent protein kinase A (PKA), which is another
59 omotes nucleotide excision repair (NER) in a cAMP-dependent protein kinase A (PKA)-dependent manner.
60 with cardiac ryanodine receptors (RyR2), and cAMP-dependent protein kinase A (PKA)-dependent phosphor
61 n of Rap1 by cyclic AMP (cAMP) can occur via cAMP-dependent protein kinase A (PKA)-independent and PK
62 was oligomycin-insensitive and contingent on cAMP-dependent protein kinase A (PKA)-induced lipolysis.
68 , a specific isoform of the second messenger cAMP-dependent protein kinase A (PKAalpha) rapidly phosp
69 onical pathway involving both an increase in cAMP-dependent protein kinase A activity and the GLI3R t
70 tion, but inhibition of either calmodulin or cAMP-dependent protein kinase A activity blunted the hyp
71 based community maps of the kinase domain of cAMP-dependent protein kinase A allow for a molecular ex
73 T, and dmLT promote human Th17 responses via cAMP-dependent protein kinase A and caspase-1/inflammaso
74 7/gp78-reconstituted system with and without cAMP-dependent protein kinase A and PKC, two liver cytos
75 n of recombinant mouse PDE3A with PKB/Akt or cAMP-dependent protein kinase A catalytic subunits leads
76 diating the dual effects of PTH, whereas the cAMP-dependent protein kinase A pathway appears to predo
80 h-affinity state and activated the canonical cAMP-dependent protein kinase A signaling pathway in car
81 Reduction in GluR1 phosphorylation at its cAMP-dependent protein kinase A site by the synthetic pe
83 tional landscape of the catalytic subunit of cAMP-dependent protein kinase A, a ubiquitous phosphoryl
84 cyclase VI and the catalytic subunit of the cAMP-dependent protein kinase A, were predicted as direc
85 increased phosphorylation of Hsp90alpha in a cAMP-dependent protein kinase A-dependent manner, and th
86 rol correlated with changes in the levels of cAMP-dependent protein kinase A-mediated phosphorylation
92 and shift in DNA organization act through a cAMP-dependent protein-kinase A-coupled signaling pathwa
93 disrupting hippocampal protein synthesis and cAMP-dependent-protein kinase A after the reactivation o
95 ophil apoptosis, as did inhibition of type I cAMP-dependent protein kinases activated downstream of P
97 of the G(alpha)s G-protein subunit and cAMP-cAMP-dependent protein kinase activation, the nitric oxi
98 renol-stimulated cAMP production (p = 0.04), cAMP-dependent protein kinase activity (p < 0.0004), pho
99 This result was consistent with attenuated cAMP-dependent protein kinase activity and reduced cyclo
100 stimulation of steroidogenesis by increasing cAMP-dependent protein kinase activity in both primary i
101 These agents were used to monitor endogenous cAMP-dependent protein kinase activity in erythrocyte ly
102 aracterize the compartmentalized location of cAMP-dependent protein kinase activity in mitochondria.
103 ndent protein kinase II activity, but not on cAMP-dependent protein kinase activity or presynaptic me
104 xemplifies two different ways for regulating cAMP-dependent protein kinase activity through non-conse
106 acting AKAP and suggest a mechanism by which cAMP-dependent protein kinase-AKAP binding can be modula
108 tic mutants in the phosphorylation sites for cAMP-dependent protein kinase and Ca(2)(+)/calmodulin-de
109 that Ca(V)1.1-S1575 is a substrate for both cAMP-dependent protein kinase and calcium/calmodulin-dep
110 effects are dependent on phosphorylation by cAMP-dependent protein kinase and cyclin-dependent prote
111 ly important neuromodulator uses synergistic cAMP-dependent protein kinase and endoplasmic reticulum
112 ypoglycemia, and catecholamine signaling via cAMP-dependent protein kinase and phosphorylation of inh
114 /dephosphorylation of serine 196 mediated by cAMP-dependent protein kinase and protein phosphatase.
115 l binding between the regulatory subunits of cAMP-dependent protein kinase and the anchoring domains
117 se activity and prevented phosphorylation by cAMP-dependent protein kinase at the neighboring Ser res
119 s and via activation of adenylyl cyclase and cAMP-dependent protein kinase, but some alternative down
120 a single phosphate to the activation loop of cAMP-dependent protein kinase by comparing the wild type
125 sphorylation of its regulatory (R) domain by cAMP-dependent protein kinase catalytic subunit (PKA).
126 ites are highly conserved among AGC kinases (cAMP dependent Protein Kinase, cGMP dependent Protein Ki
128 so show that the regulation is via cAMP/PKA (cAMP-dependent protein kinase)-dependent signaling and p
133 atically potentiated following activation of cAMP-dependent protein kinase in DT40-3KO cells transien
135 evels, as indicated by experiments using the cAMP-dependent protein kinase inhibitors H89 and PKI.
136 -3 induction by cAMP occurs independently of cAMP-dependent protein kinase, instead requiring the rec
138 glycoprotein inhibition was attributable to cAMP-dependent protein kinase-mediated inhibition of the
140 potentiation of the synaptic response via a cAMP-dependent protein kinase-mediated postsynaptic mech
142 hat mutation of the phosphorylation site for cAMP-dependent protein kinase on DARPP-32 attenuates l-D
143 ich of the two main cAMP sensors is at play: cAMP-dependent protein kinase or exchange protein direct
144 RI and RII) of the regulatory (R) subunit of cAMP-dependent protein kinase or protein kinase A (PKA)
145 y activation of the beta-adrenergic receptor/cAMP-dependent protein kinase pathway and up-regulation
146 s the clinical and molecular genetics of the cAMP-dependent protein kinase pathway in human pituitary
148 nnels probably by interference with the cAMP/cAMP-dependent protein kinase pathway, resulting in a de
149 r713 phosphorylation through inhibition of a cAMP-dependent protein kinase/phosphatase-2A cascade.
151 g protein mAKAP serves as a scaffold for the cAMP-dependent protein kinase PKA and the cAMP-specific
154 control, the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) holoenzyme typicall
155 gical state, cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) is a tetramer that
156 ) subunit of cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) is inhibited by two
157 AR1A) of the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA), leading to activat
160 prototypical cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA-RIalpha), for which
162 ic mechanism of phosphorylation catalyzed by cAMP-dependent protein kinase (PKA) a structure of the e
163 receptors and intracellular cAMP binding to cAMP-dependent protein kinase (PKA) act together to indu
166 eases glucagon-stimulated cAMP accumulation, cAMP-dependent protein kinase (PKA) activity and downstr
167 tegrin function-blocking antibodies enhances cAMP-dependent protein kinase (PKA) activity and increas
169 udied the therapeutic potential of beta-cell cAMP-dependent protein kinase (PKA) activity in restorin
170 fusion transcript, which leads to increased cAMP-dependent protein kinase (PKA) activity in the inde
172 educed, but the increases in cAMP levels and cAMP-dependent protein kinase (PKA) activity were unaffe
173 gulation required receptor signaling via the cAMP-dependent protein kinase (PKA) and a specific PKA c
174 NOS and also abrogated epinephrine-dependent cAMP-dependent protein kinase (PKA) and Akt activation.
176 ex that controls the opposing actions of the cAMP-dependent protein kinase (PKA) and CaN in regulatio
178 e majority of cAMP functions are mediated by cAMP-dependent protein kinase (PKA) and exchange protein
179 family of proteins (AKAPs), which target the cAMP-dependent protein kinase (PKA) and other enzymes to
180 Previous reports have implicated type I cAMP-dependent protein kinase (PKA) and p90 ribosomal S6
181 found in dendritic spines that recruits the cAMP-dependent protein kinase (PKA) and protein phosphat
182 horing protein (AKAP)79/150 targets both the cAMP-dependent protein kinase (PKA) and protein phosphat
183 naling cascade, which leads to activation of cAMP-dependent protein kinase (PKA) and subsequent cardi
184 ed that it is regulated by the activities of cAMP-dependent protein kinase (PKA) and the protein phos
186 rotein directly activated by cAMP (EPAC) and cAMP-dependent protein kinase (PKA) are two intracellula
190 ion of the adenine ring selectively activate cAMP-dependent protein kinase (PKA) but not exchange pro
192 Previously, we described the inactivation of cAMP-dependent protein kinase (PKA) by direct oxidation
193 Subcellular compartmentalization of the cAMP-dependent protein kinase (PKA) by protein kinase A-
194 cal antagonism of NMDA receptors (NMDARs) or cAMP-dependent protein kinase (PKA) during post-MD sleep
195 trimeric G(s) protein, adenylyl cyclase, and cAMP-dependent protein kinase (PKA) for efficient signal
196 cellular model of memory storage, implicate cAMP-dependent protein kinase (PKA) in presynaptic and p
199 le is known about the regulation of cAMP and cAMP-dependent protein kinase (PKA) in these cells.
201 ve found that ET1 stimulates the activity of cAMP-dependent protein kinase (PKA) in VSMC as profoundl
202 ptors, phosphorylation of CaV1.2 channels by cAMP-dependent protein kinase (PKA) increases channel ac
203 cellular metabolism, we found here that the cAMP-dependent protein kinase (PKA) inhibitor H89 increa
210 yses of the cAMP binding domains of Epac and cAMP-dependent protein kinase (PKA) lead to a model of E
212 dramatically increased by activation of the cAMP-dependent protein kinase (PKA) pathway, which is im
217 r study has revealed age-related increase in cAMP-dependent protein kinase (PKA) phosphorylation of t
218 ked G protein-coupled receptor activation of cAMP-dependent protein kinase (PKA) plays an important r
219 isualise these two processes by studying the cAMP-dependent protein kinase (PKA) potentiation of pres
226 by FRET fluorescence ratio changes of tagged cAMP-dependent protein kinase (PKA) subunits expressed u
227 he well designed compartmentalization of the cAMP-dependent protein kinase (PKA) through its anchorin
228 A kinase anchor protein AKAP150 recruits the cAMP-dependent protein kinase (PKA) to dendritic spines.
229 kinase anchoring proteins (AKAPs) tether the cAMP-dependent protein kinase (PKA) to intracellular sit
230 inase anchoring proteins (AKAPs) that target cAMP-dependent protein kinase (PKA) to the channel.
231 damental cellular processes by directing the cAMP-dependent protein kinase (PKA) toward its intended
232 atio-temporal specificity for the omnipotent cAMP-dependent protein kinase (PKA) via high affinity in
234 ort, novel substrate-binding variants of the cAMP-dependent protein kinase (PKA) were used to identif
235 To determine the physiological role of the cAMP-dependent protein kinase (PKA), a mouse model was d
236 two catalytic subunits (Calpha and Cbeta) of cAMP-dependent protein kinase (PKA), a pleiotropic holoe
238 r mechanism of activation, dependence on the cAMP-dependent protein kinase (PKA), and the magnitude a
239 sensory neurons results in the activation of cAMP-dependent protein kinase (PKA), and this kinase pho
240 h the negative feedback loop formed by cAMP, cAMP-dependent protein kinase (PKA), and type 4 phosphod
241 inuing activity of adenylyl cyclase (AC) and cAMP-dependent protein kinase (PKA), as well as a scaffo
242 is a human anchoring protein that organizes cAMP-dependent protein kinase (PKA), Ca(2+)/calmodulin (
243 on of the c-fos gene conferred regulation by cAMP-dependent protein kinase (PKA), cGMP-dependent prot
244 kinetics of sites that are phosphorylated by cAMP-dependent protein kinase (PKA), even in highly homo
245 lated on threonine residue 35 (Thr35) by the cAMP-dependent protein kinase (PKA), inducing the potent
246 rements of global cAMP, general increases in cAMP-dependent protein kinase (PKA), or the activity of
248 JB1 is fused to the catalytic (C) subunit of cAMP-dependent protein kinase (PKA), replacing exon 1, t
249 reveal that the type I regulatory subunit of cAMP-dependent protein kinase (PKA), RIalpha, undergoes
251 nels is subject to pronounced enhancement by cAMP-dependent protein kinase (PKA), which is scaffolded
270 required NR2B-mediated downregulation of the cAMP-dependent protein kinase (PKA)/cAMP response elemen
271 ve small-molecule regulators for type Ialpha cAMP-dependent Protein kinase (PKA-Ialpha), a protein co
273 gnaling can regulate and be regulated by the cAMP-dependent protein kinase, PKA, although the molecul
274 t lead to an increase in the activity of the camp-dependent protein kinase, PKA, which triggers rapid
275 y, we reported that the catalytic subunit of cAMP-dependent protein kinase (PKAc) binds to the active
280 a pathway that is sensitive to inhibitors of cAMP-dependent protein kinase [protein kinase A (PKA)].
281 al cells, serine/threonine kinases including cAMP-dependent protein kinase, protein kinase C and calm
282 and poor inhibition of other members of the cAMP-dependent protein kinase/protein kinase G/protein k
284 nding of RSPH3 to the regulatory subunits of cAMP-dependent protein kinase, RIIalpha and RIIbeta, is
285 volving mitogen-activated protein kinase and cAMP-dependent protein kinase signaling modules, wherein
286 ilar level in TG-RLC(P-) and NTG, suggesting cAMP-dependent protein kinase signaling to these protein
287 nuclear localization during fasting and cAMP/cAMP-dependent protein kinase signaling, suggesting loca
288 CRE-binding protein (CREB) or activation of cAMP-dependent protein kinase significantly increased GL
289 C5a orthologs efflux cyclic nucleotides, and cAMP-dependent protein kinase (Sp-CAPK/PKA) is expressed
290 hosphorylation of Synapsin I/II at serine 9 (cAMP-dependent protein kinase substrate site), serine 62
291 somatic mutations in PRKACA, which encodes a cAMP-dependent protein kinase that acts as a repressor p
292 Ps), defined by their capacity to target the cAMP-dependent protein kinase to distinct subcellular lo
293 activate mechanisms in addition to cAMP and cAMP-dependent protein kinase to modulate retinal gangli
294 ceptors (betaAR) in adipocytes activates the cAMP-dependent protein kinase to promote liberation of f
295 of cAMP, in parallel with the stimulation of cAMP-dependent protein kinase, to drive ribosomal protei
296 ssion of a non-coding transcript of PRKAR1A (cAMP-dependent protein kinase type I-alpha regulatory su
297 rotein kinases (Pim-1, Pim-2, and Pim-3) and cAMP-dependent protein kinase were measured and found to
298 ptors that increase cAMP levels and activate cAMP-dependent protein kinase, which phosphorylates mamm
299 ccessfully applied to detect the activity of cAMP-dependent protein kinase with a low detection limit
300 surprising peptidergic transmission requires cAMP-dependent protein kinase, with only a minor contrib