ライフサイエンスコーパス: cactus

1 ) were previously unknown for any species of cactus.

2 transcription factor inhibitor (Ikappabeta) cactus.

3 o degradation of the IkappaB-like inhibitor, Cactus.

4 m require facilitated diffusion of Dorsal by Cactus.

5 lated inhibition of Dorsal nuclear uptake by Cactus.

6 d in the spatially controlled degradation of Cactus.

7 the cytoplasm by the IkappaB-family protein Cactus.

8 al phosphorylation, but still interacts with Cactus.

9 ned in the cytoplasm by the IkappaB protein, Cactus.

10 om activated Toll to a complex of Dorsal and Cactus.

11 sal and Dif is accompanied by degradation of Cactus.

12 induces the spatially graded degradation of Cactus.

13 ytoplasmic Dorsal from the I kappa B homolog Cactus.

14 kinase, Pelle, placed upstream of Dorsal and Cactus.

15 for soil and + 9.8 (N = 212, S.D. = 3.4) for cactus.

16 d outside the nucleus by the IkappaB homolog Cactus.

17 roperties distinct from those of full-length Cactus.

18 stribution of different LAA morphologies was Cactus (278 [30%]), Chicken Wing (451 [48%]), Windsock (

19 eabird + 19.7, guano + 14.8, soil + 34.3 and cactus + 30.3 compared to average values across non-bird

20 Cactus(6), a reference-free multiple genome alignment pr

21 f the Dorsal signaling module and found that Cactus, a cytoplasmic inhibitor for Dorsal, must be pres

22 signaling in Anopheles gambiae by silencing Cactus, a suppressor of this pathway, enhances local rel

23 Finally, we provide evidence that Dorsal and Cactus act posttranscriptionally, outside the nucleus, t

24 lated in vivo and are required for wild-type Cactus activity.

25 These results indicate that Cactus acts to bolster Dorsal activation, in addition to

26 ave implemented these algorithms in the new "Cactus" alignment program.

27 lieve inhibition of Dorsal nuclear uptake by Cactus, allowing Dorsal to enter the nucleus and activat

28 rotein Dorsal from its cytoplasmic inhibitor Cactus, allowing Dorsal to translocate into ventral and

29 n lateral and dorsal embryo domains, loss of Cactus allows more Dorsal to translocate to the nucleus.

30 The silencing of Cactus also led to developmental arrest and death of the

31 rlapping with I kappa B-alpha, as well as to cactus, an I kappa B homolog of Drosophila.

32 Toll mutant and a loss-of-function mutant of Cactus, an I kappa B-like factor that inhibits the Toll

33 ved in the mosquitoes with RNAi knockdown of Cactus, an IkappaB inhibitor in the Toll/REL1 pathway.

34 knockdown of an Aedes homolog to Drosophila cactus, an IkappaB inhibitor of Drosophila Toll pathway.

35 First, we assume that Cactus, an inhibitor that binds to Dorsal and prevents i

36 Simultaneous knockdown of cactus and AGAP001476 failed to reverse the near refract

37 g-down their respective negative modulators (Cactus and Caspar) increases LDs numbers in the midgut.

38 entral signal-dependent modification of both Cactus and Dorsal is required for the graded nuclear imp

39 As maternally encoded proteins, Toll, Cactus and Dorsal, along with Tube and Pelle, participat

40 radient requires the phosphorylation of both Cactus and Dorsal.

41 l dissociates from its cytoplasmic inhibitor Cactus and enters the nucleus.

42 e ventralized phenotype of embryos that lack Cactus and faithfully reconstitutes dorsal group-regulat

43 fruits, and to investigate the efficiency of cactus and moringa callus oils in controlling this pest.

44 ts degradation of the IkappaB-like inhibitor Cactus and nuclear translocation of the Rel protein Dors

45 ases levels of the I(kappa)B-related protein Cactus and reduces the magnitude of the nuclear concentr

46 interactor of the Drosophila IkappaB factor Cactus and shown to play a role in controlling embryonic

47 tion of Cactus results in the degradation of Cactus and the nuclear targeting of Dorsal.

48 The number of mitotic cells in the cactus and TollD hemolymph is higher than that in the wi

49 era truncata (crab cactus or false Christmas cactus), and interrogated them for tissue-specific expre

50 Through genetic studies, Tube, Pelle, Cactus, and Dif have been identified as downstream compo

51 We propose a model in which Tube, Pelle, Cactus, and Dorsal form a multimeric complex that repres

52 We then show that mutations in dorsal, cactus, and IRAK/pelle kinase specifically impair GluR l

53 is encoded by Toll, tube, pelle, dorsal, and cactus, and it functions to form the dorsal-ventral axis

54 ased upon our data we speculate that Dorsal, Cactus, and Pelle could function together, locally at th

55 by the ventral signal while associated with Cactus, and that Dorsal phosphorylation is essential for

56 Dorsal binds specifically to Tube, Pelle and Cactus, and that the protein kinase activity of Pelle di

57 Lethality of mutant cactus animals could be rescued either by the selective

58 on of fusion proteins comprising segments of Cactus attached to Escherichia coli beta-galactosidase (

59 Cactus berry (Myrtillocactus geometrizans) is a scarcely

60 Cactus berry fruit should be considered a promising frui

61 study the betalains and phenolic profile in cactus berry, their in vitro biological activities and g

62 e terrestrial plant production in the cardon cactus beyond that seen in either mainland ecosystems or

63 orsal Rel homology region rather than at the Cactus binding site.

64 lear localization signal is not required for Cactus binding.

65 ments of Dorsal reflect both free Dorsal and Cactus-bound Dorsal.

66 ecades, partly due to destruction of Opuntia cactus by introduced goats, whereas Geospiza fortis has

67 We identified Cactus (Cact, mammalian IkBa), the negative regulator of

68 e the major bioactive components detected in cactus callus oil while (E)-9-Octadecenoic acid, ethyl e

69 Cactus callus-derived oils were more lethal to medfly (u

70 nia, and an online cancer support community (Cactus Cancer Society).

71 us forests, especially of the large columnar cactus, cardon (Pachycereus pringlei).

72 adjacent areas, including the iconic saguaro cactus (Carnegiea gigantea) of the Sonoran Desert.

73 classified into four morphologies: broccoli, cactus, chicken wing and windsock.

74 he prevalence of pre-procedure stroke/TIA in Cactus, Chicken Wing, Windsock, and Cauliflower morpholo

75 nt morphologies were used to categorize LAA: Cactus, Chicken Wing, Windsock, and Cauliflower.

76 Cactus cladode offers innovative ingredients such as cac

77 ant capacity and (poly)phenolic compounds of cactus cladodes (Opuntia ficus-indica) was evaluated.

78 Component Analysis distributed heat treated cactus cladodes according to their distinctive polypheno

79 Cactus cladodes fried in olive oil showed a healthier fa

80 naling on the ventral side breaks the Dorsal/Cactus complex, allowing Dorsal to enter the nucleus to

81 to relay the signal from Toll to the Dorsal-Cactus complex.

82 tated diffusion, or shuttling, of the Dorsal/Cactus complex.

83 ude that dorsoventral signaling results in a Cactus concentration gradient and propose that signal-de

84 The antioxidant properties of red cactus cultivar were higher than the yellow cactus culti

85 cactus cultivar were higher than the yellow cactus cultivar.

86 onal and pharmaceutical potential of the two cactus cultivars that must be widespread cultivated in a

87 Signal-induced Cactus degradation frees Dorsal for nuclear translocatio

88 e system which reconstitutes Pelle-dependent Cactus degradation, we show that a motif in Cactus resem

89 y reducing a signal-independent component of Cactus degradation.

90 IkappaB-beta is essential for Pelle-induced Cactus degradation.

91 Seabird island soil and cactus delta(15)N values were consistently significantly

92 P001476-mediated anti-Plasmodium response is Cactus-dependent.

93 Cactus depletion resulted in transcriptional activation

94 The immune effects caused by Cactus depletion were eliminated by double knockdown of

95 must discriminate between Cactus-Dorsal and Cactus-Dif complexes.

96 variables were intermediate, indicating that cactus diversification is promoted by moderate, not extr

97 ults reveal the potential primary drivers of cactus diversification, and the need to account for the

98 us for degradation must discriminate between Cactus-Dorsal and Cactus-Dif complexes.

99 uring early Drosophila development, the Toll-Cactus-Dorsal pathway regulates the establishment of the

100 milarities exist between the Drosophila Toll/Cactus/Dorsal signaling pathway and the mammalian cytoki

101 formance by mapping mescaline in a San Pedro cactus ( Echinopsis pachanoi) cross section, tropane alk

102 ructs that lack the first 125 amino acids of Cactus escape dorsal group-dependent degradation.

103 Many species in the cactus family are known to express self-incompatibility

104 iotic variables shape diversification in the cactus family.

105 with establishment of industries beside the cactus farms that used all parts of plants.

106 A new paper shows that a cactus-feeding fly became restricted to its host by chan

107 eterospecific juveniles, no juveniles) for a cactus-feeding insect, Narniafemorata (Hemiptera: Coreid

108 (medium ground finch) and Geospiza scandens (cactus finch) changed several times in body size and two

109 us, ground finches have deep and wide beaks, cactus finches have long and pointed beaks (low depth an

110 gher levels in the long and pointed beaks of cactus finches than in more robust beak types of other s

111 In cactus finches, the frequency of the yellow genotype is

112 k, recapitulating the beak morphology of the cactus finches.

113 dient can behave differently with respect to Cactus fluctuations.

114 fore the two signalling pathways that target Cactus for degradation must discriminate between Cactus-

115 Several bird islands host regionally unique cactus forests, especially of the large columnar cactus,

116 that proteolytic cleavage by CalpA generates Cactus fragments lacking an N-terminal region required f

117 rotein Dorsal from its cytoplasmic inhibitor Cactus; free Dorsal translocates into nuclei and directs

118 , active Toll, the receptor that dissociates Cactus from Dorsal, must be saturated.

119 cy of the yellow genotype is correlated with cactus fruit abundance and greater hatching success and

120 The microencapsulation of betalains from cactus fruit by spray drying was evaluated as a stabiliz

121 However, there are other cactus fruit that are underutilized and understudied tha

122 e found that females laid 56% more eggs when cactus fruit was present versus when it was absent.

123 fer] Riccobono) is a relatively little known cactus fruit with a significant pharmacological potentia

124 d both resource quality (presence/absence of cactus fruit) and social cues (conspecific juveniles, he

125 Betalains were extracted from purple cactus fruits and encapsulated in calcium-alginate and i

126 tional and functional properties of selected cactus fruits from the Mexican drylands, as well as thei

127 ctly from the mash of whole Opuntia dillenii cactus fruits have been investigated.

128 There are certain types of cactus fruits that are being technologically produced.

129 etic experiments support the conclusion that cactus functions in concert with, rather than in opposit

130 rs of an unusual dorsalizing mutation in the cactus gene, cact(E10).

131 Using Cactus graphs, recently introduced for representing sequ

132 (medium ground finch) and Geospiza scandens (cactus ground finch) from 1978 to 2010 on Daphne Major I

133 jection of RNA encoding this altered form of Cactus has a dominant negative effect on establishment o

134 s species includes four genetically isolated cactus host races each individually specializing on the

135 vensis lineage at Adh-1, suggesting that the cactus host shift that occurred in the divergence of D.

136 rosophila mojavensis and D. arizonae utilize cactus hosts, and each host contains a characteristic mi

137 ificity and in the adaptation to alternative cactus hosts.

138 served in several species (e.g. prickly pear cactus, hydra and flatworms) and is indicative of their

139 ural and functional similarities (Toll/IL-1, Cactus/I-kappaB, and dorsal/NF-kappaB).

140 l pathway NFkappaB protein Dorsal as well as cactus/IkappaBeta show elevated expression in tumors wit

141 bsent in a number of species associated with cactus in arid regions.

142 rentially affects the levels and activity of Cactus in embryos, but does not inhibit the binding of C

143 Opuntia, the most abundant cactus in Mexico, produces fruit known as prickly pears

144 le for dorsal group-dependent degradation of Cactus in the absence of this motif.

145 he Drosophila melanogaster IkappaB homologue Cactus in vivo.

146 scription of the Drosophila IkappaB homolog, Cactus, in Toll receptor-mediated antimicrobial response

147 ownstream of Toll to release Dorsal from the Cactus inhibitor.

148 Phosphorylation of both Dorsal and Cactus is regulated by a Toll-receptor-dependent ventral

149 Compared to other plant taxa, this cactus is rich in polymorphic loci (Ps=89.5%), with high

150 Results showed that the cactus juice exhibited desirable technological character

151 fied Drosophila casein kinase II (CKII) as a Cactus kinase and shown that CKII specifically phosphory

152 Furthermore, Cactus-lacZ constructs that lack only the putative Ikapp

153 Full-length Cactus-lacZ expressed in vivo normalizes the ventralized

154 pha can also direct polarized degradation of Cactus-lacZ fusion protein.

155 In addition, the lymph glands of cactus larvae are considerably enlarged.

156 Phosphorylation of Cactus leads to its degradation and to the release of Do

157 ence suggesting that Dpp signaling increases Cactus levels by reducing a signal-independent component

158 phylogenomic approach, we estimated that the cactus lineage diverged from its closest relatives appro

159 Diversification rates of several cactus lineages rival other estimates of extremely rapid

160 loned by chromosomal walking from the nearby cactus locus.

161 Unexpectedly, cactus loss-of-function alleles decrease Dorsal nuclear

162 ogate native congener host in Argentina, the cactus mealybug Hypogeococcus sp., was studied to predic

163 tivity at least in part by counteracting the Cactus-mediated inhibition of Dorsal nuclear localizatio

164 c diversity was measured in the mixed-mating cactus, Melocactus curvispinus, in Venezuela.

165 Here, we investigate how cactus modulates Toll signals through its effects on the

166 e Drosophila immune organ, leads to elevated cactus mRNA levels, decreased expression of antimicrobia

167 ladode offers innovative ingredients such as cactus mucilage (CM) and cladode flour (CF) for producin

168 Cactus mucilage (CMU) have been widely studied in variou

169 A combination of cactus mucilage and ferric (Fe(III)) salt was investigat

170 We explore the application of cactus mucilage, pectic polysaccharide extracts from Opu

171 of genomes, the generation of reference-free Cactus multiple sequence alignments of these genomes, an

172 it completely destabilizes the protein in a cactus mutant background.

173 Analysis of cactus mutants that lack Cactus protein revealed that al

174 In cactus mutants we found an additional kind of melanized

175 Therefore, Cactus not only has the primary role of regulating Dorsa

176 The use of callus-derived oils from cactus (Opuntia ficus indica (L.) Mill.) and moringa (Mo

177 onals were characterized in two prickly pear cactus (Opuntia ficus indica Mill.) cultivars; red and y

178 scriptomes from Schlumbergera truncata (crab cactus or false Christmas cactus), and interrogated them

179 Mutations in cactus or Toll, or constitutive expression of dorsal can

180 lly used in the food industry (e.g., pitaya, cactus, or prickly pear) or as pharmaceuticals to treat

181 tion about their age, but progress in dating cactus origins has been hindered by the lack of fossil d

182 ing factor and/or discriminant analysis, the cactus pad samples were clearly differentiated according

183 Consumption of cactus pads contributes to the intake of dietary fiber,

184 g, Fe, Cu, Zn, Mn and Cr) were determined in cactus pads from Opuntia dillenii and Opuntia ficus indi

185 and green fruit pulp of O. ficus indica; the cactus pads of O. dillenii could be differentiated accor

186 Here we present the Minigraph-Cactus pangenome pipeline, which creates pangenomes dire

187 hat the intracellular portion of the Toll to Cactus pathway also controls the innate immune response

188 hemical and physiological ripening events in cactus pear (Opuntia ficus-indica) fruit of cultivars 'N

189 Pulp (CP) and ultrafiltered (UF) cactus pear extracts were encapsulated with Capsul (C) b

190 rvest handling protocols for premium quality cactus pear fruit.

191 compounds and betalains are characterized in cactus pear juice using a single LC-DAD-ESI-MS/MS method

192 and Stenocereus) and a more distant outgroup cactus, Pereskia We used these to construct 4,436 orthol

193 t and control strategies of the Puerto Rican cactus pest and shed light on the evolutionary pathways

194 orylates a set of serine residues within the Cactus PEST domain.

195 quires CKII-catalyzed phosphorylation of the Cactus PEST domain.

196 l biocontrol agents against the Puerto Rican cactus pest mealybug, Hypogeococcus sp. (Hemiptera: Pseu

197 Montipora setosa, Pachyseris rugosa, Pavona cactus, Plerogyra sinuosa, Pocillopora acuta, Seriatopor

198 e Toll stems from the mobilization of a free Cactus pool induced by the Calpain A protease.

199 eracts physically with Cactus, recognizing a Cactus pool that is not bound to Dorsal, a fly NFkappaB/

200 ueling the production of some of the densest cactus populations in the world.

201 her by the selective expression of wild-type Cactus protein in the larval lymph gland or by the intro

202 Analysis of cactus mutants that lack Cactus protein revealed that almost all of these animals

203 inhibitor, IkappaBalpha, and the Drosophila Cactus protein.

204 rects the spatially regulated proteolysis of Cactus protein.

205 CalpA alters the absolute amounts of Cactus protein.

206 retention of both Dorsal and Dif depends on Cactus protein; nuclear import of Dorsal and Dif is acco

207 Major cactus radiations were contemporaneous with those of Sou

208 vidence that CalpA interacts physically with Cactus, recognizing a Cactus pool that is not bound to D

209 , covering 2.9 million base pairs of the Adh-cactus region of chromosome 2 and 85,000 base pairs of t

210 Cactus degradation, we show that a motif in Cactus resembling the sites of signal-dependent phosphor

211 induces degradation of the IkappaB inhibitor Cactus, resulting in a ventral-to-dorsal nuclear gradien

212 Signal-dependent phosphorylation of Cactus results in the degradation of Cactus and the nucl

213 etion were eliminated by double knockdown of Cactus/RUNX4.

214 Finally, we make an empirical assessment of Cactus's ability to properly align genes and find intere

215 easurements, which were compared to soil and cactus samples from other seabird and non-seabird Gulf i

216 Fish, seabird, guano, soil, and cactus samples were taken from the representative seabir

217 analyzing A in urine and mescaline (MSC) in cactus samples.

218 The data indicate that the defatted cactus seed wastes still contain various components that

219 Our results suggest that the Toll/Cactus signal transduction pathway plays a significant r

220 ow using these and existing simulations that Cactus significantly outperforms all of its peers.

221 Cactus silencing triggers a Rel1-mediated differentiatio

222 ses for the divergence of the island-endemic cactus species Cereus insularis Hemsl.

223 We selected 55 cactus species from the Americas, all geo-referenced see

224 ame an important pest that threatens endemic cactus species in Puerto Rico, and Hyp-AP feeds on Amara

225 root biomass gathered for the large columnar cactus species Pachycereus pringlei.

226 The necrosis of each cactus species provides the resident D. mojavensis popul

227 vative scenario (+3.7 degrees C) that 25% of cactus species will have reduced germination performance

228 Pilosocereus machrisii and P. aurisetus are cactus species within the P. aurisetus complex, a group

229 izing on the necrotic tissues of a different cactus species.

230 ions in Baja as well as from closely related cactus species.

231 nin types in the seed coats of 130 different cactus species.

232 ange of structural curvatures, from straight cactus spines to crescent-shaped talons found in raptors

233 geometry with a widening slope, analogous to cactus spines, directly couples facilitated droplet grow

234 ing on conical wire-like structures, such as cactus spines, spider silk, and water striders' legs.

235 with the support of experimental results on cactus spines.

236 Cactus stability is regulated by amino-terminal serine r

237 r refractoriness induced by the knockdown of cactus, suggesting that the AGAP001476-mediated anti-Pla

238 he NF-kappaB and IkappaB homologs Dorsal and Cactus surround postsynaptic glutamate receptor (GluR) c

239 tly acting determinants in the N terminus of Cactus that direct dorsal group-dependent degradation.

240 ylatable alanine residues generated a mutant Cactus that still functions as a Dorsal inhibitor but is

241 Regulated proteolysis of Cactus, the cytoplasmic inhibitor of the Rel-related tra

242 in the presence of a non-signaling allele of Cactus, the IkappaB protein in Drosophila.

243 y of ultrasonography in the detection of the cactus thorn was 5%, whereas it ranged between 82.5 and

244 ong peanut shell, < 1 cm rose spikes, < 1 cm cactus thorns, < 1 cm pellets, and < 1 cm staples were i

245 known Dorsal-interacting proteins (Twist and Cactus), three that encode novel proteins, and one that

246 Here we describe progressive extensions to Cactus to create Progressive Cactus, which enables the r

247 embryos, but does not inhibit the binding of Cactus to Dorsal.

248 ssion analysis suggests that this ability of Cactus to enhance Toll stems from the mobilization of a

249 Cactus, Toll, Tube and Pelle proteins are expressed in t

250 ghlight the importance of regulating IkappaB/Cactus transcription in innate immunity, and identify Gr

251 Both vitellogenin and TEP1 are regulated by Cactus under the Toll pathway.

252 We test Cactus using the Evolver genome evolution simulator, a c

253 translation enhancer (PTE) from the saguaro cactus virus (SCV), using a Fab crystallization chaperon

254 Compared with chicken wing, cactus was 4.08 times (p = 0.046), Windsock was 4.5 time

255 pulation genetic structure observed for this cactus was attributed to, at least, three factors: short

256 Dorsal protein that failed to interact with Cactus was still regulated by the ventral signal.

257 ion, nuclear targeting, and interaction with Cactus, we have performed an in vivo structure-function

258 e extensions to Cactus to create Progressive Cactus, which enables the reference-free alignment of te

259 n with its cognate IkappaB inhibitor protein Cactus, which is degraded on the ventral side of the emb

260 We propose that CalpA targets free Cactus, which is incorporated into and modulates Toll-re

261 rearrangement tree based on blocks from the Cactus whole-genome aligner was fully compatible with th

262 Finally, we present a Progressive Cactus whole-genome, reference-free alignment built from

263 Cactus with fruit is a high-quality environment for juve