ライフサイエンスコーパス: caffeine

1 th stronger associations observed for coffee caffeine.

2 tryptophan, and from 16.6 nM to 333 muM for caffeine.

3 ototoxicity following oral administration of caffeine.

4 e-promoting psychostimulants, armodafinil or caffeine.

5 but not electrocortical, arousal response to caffeine.

6 on coupled with electrochemical detection of caffeine.

7 nsiderable amounts of phenolic compounds and caffeine.

8 ary stenosis, and after preadministration of caffeine.

9 omotion after treatment with A2A antagonist, caffeine.

10 which suggests a novel protection window by caffeine.

11 the phenolic compounds chlorogenic acid and caffeine.

12 ic effect, dismissing the systemic action of caffeine.

13 dihydroxy-6-methyl-4H-pyran-4-one (DDMP) and caffeine.

14 fission yeast grown with threshold levels of caffeine.

15 cting gradual RyR inactivation with >=1.0 mM caffeine.

16 st widely self-administered drugs other than caffeine.

17 ch makes them less effective at metabolizing caffeine.

18 ce was stronger for coffee caffeine than tea caffeine.

19 gan are dexamethasone (<2.54-37.23 ng/g) and caffeine (0.21-18.92 ng/g).

20 Stem cell-derived adipocytes exposed to caffeine (1 mM) showed increased UCP1 protein abundance

21 Caffeine (1.25g/100g), chlorogenic acid (246mg/100g), an

22 L-Theanine (2.5 mg/kg), caffeine (2.0 mg/kg), their combination and a placebo we

23 stimulated with normal consumption levels of caffeine (3 muM and 10 muM), over a period of 9 h.

24 Caffeine (5, 10, or 15 mg/kg), a nonspecific adenosine r

25 After preadministration of caffeine, a known inhibitor of adenosine, resting MBF de

26 Coffee seeds also contain caffeine, a pharmaceutically important methylxanthine.

27 d chronic animal pain models, oral intake of caffeine, a potent adenosine receptor antagonist, interf

28 Here we study caffeine, a widely consumed drug that undergoes oligomer

29 Inhibition of A(1)AR by caffeine, a widely consumed psychoactive substance, coul

30 orcing effectiveness of MDPV, methylone, and caffeine, administered alone and as binary mixtures (n=1

31 n with intubation, early enteral feeding and caffeine administration.

32 Caffeine affects two anti-silencing factors: Epe1 is dow

33 Caffeine also increased peroxisome proliferator-activate

34 al lead, caffeine, and simultaneous lead and caffeine analysis via LA-LS-APGD-MS was made possible th

35 The beverage Cascara contained 226mg/L of caffeine and 283mgGAE/L of total polyphenols whereas ant

36 It was determined that caffeine and 3-CGA concentrations reached equilibrium ac

37 n kinetics and equilibrium concentrations of caffeine and 3-chlorogenic acid (3-CGA) in cold brew cof

38 ent and -independent mechanisms, as combined caffeine and A2AR knockout produced additive and nearly

39 dependent mechanism, as revealed by combined caffeine and A2AR-knockout treatment.

40 e the presence of well-removed OWCs, such as caffeine and acetaminophen, may indicate discharges of p

41 cts with evening-type families showed higher caffeine and alcohol consumption (p < 0.001).

42 essibility and bioavailability of phenolics, caffeine and antioxidant activity of wheat bread enriche

43 By contrast, the pore of the ATP, caffeine and Ca(2+)-activated channel remains open in th

44 Caffeine and carbamazepine showed correlations with flor

45 display elevated GLU levels after consuming caffeine and carbohydrate (CHO + CAFF) versus carbohydra

46 1D (1)H NMR were identified as trigonelline, caffeine and chlorogenic and organic acids.

47 ght a possible drug-drug interaction between caffeine and cisplatin for ototoxicity and suggest that

48 agonist, reversed the detrimental actions of caffeine and cisplatin on hearing loss.

49 The suspension was then supplemented with caffeine and gelatinized to fabricate hydrogels which we

50 rature ratios, studying bioactive compounds (caffeine and individual catechins), antioxidant capacity

51 An LC-MS/MS method quantifying caffeine and its metabolite paraxanthine in dried whole

52 respond normally to cytosolic Ca(2+) , ATP, caffeine and luminal Ca(2+) .

53 Caffeine and modafinil, two wake-promoting agents that h

54 alyzed in these sections: diethyl phthalate, caffeine and nicotine.

55 om control diets was affected by exposure to caffeine and pharmaceutical mixture treatments.

56 ub-phenotype analyses targeting the alcohol, caffeine and sweetener components of beverages yielded a

57 the antioxidant potential of bread; however, caffeine and synergism between antioxidants are also imp

58 adly similar between the group that received caffeine and the group that received placebo.

59 forces of FDB fibers increase in response to caffeine and the troponin-calcium stabilizer tirasemtiv,

60 We examined the acute effects of L-theanine, caffeine and their combination on sustained attention, i

61 ally induced by methylxanthine drugs such as caffeine and theophylline, which are contraindicated in

62 to the increased production of catechins and caffeine and thus enhance tea-processing suitability and

63 normally to cytosolic Ca(2+) , ATP, adenine, caffeine and to luminal Ca(2+) .

64 : caffeine, and 3 : 1 and 1 : 1 methylone : caffeine) and sub-additive (3 : 1, 1 : 1, and 1 : 3 MDPV

65 P concentration and is inhibited by heparin, caffeine, and 2-aminomethoxydiphenyl borate (2-APB).

66 salts mixtures, supra-additive (3 : 1 MDPV : caffeine, and 3 : 1 and 1 : 1 methylone : caffeine) and

67 s and small molecules including Ca(2+), ATP, caffeine, and PCB95.

68 Elemental lead, caffeine, and simultaneous lead and caffeine analysis vi

69 nusual forms of stress such as heavy metals, caffeine, and the plasticizer phthalate.

70 stematically investigated with theophylline, caffeine, and theobromine.

71 ted with the concentrations of ibuprofen and caffeine, anthropogenic indicators of untreated wastewat

72 ebo-controlled randomized trials of neonatal caffeine are unlikely.

73 WAS variants, including those implicated for caffeine (ARID3B/CYP1A1), carbohydrate metabolism (FGF21

74 ochromatin-dependent epimutants resistant to caffeine arise in fission yeast grown with threshold lev

75 ia, such as Pseudomonas putida CBB5, utilize caffeine as a sole carbon and nitrogen source by degradi

76 We prove this principle using caffeine as a substrate in vitro and then apply it in vi

77 h and follicular diffusion are studied using caffeine as an illustrative compound.

78 ggregates was explored in water, considering caffeine as the "target analyte".

79 mune system processes were down-regulated by caffeine at 3 h.

80 Dietary caffeine at a human-relevant dose synergizes adverse per

81 Local administration of caffeine at the acupuncture point was sufficient to elim

82 Moreover, caffeine attenuated not only hypoxia-induced pathologic

83 DPV being the most potent and effective, and caffeine being the least potent and effective of the thr

84 feine were identified, with trigonelline and caffeine being those with the highest concentration.

85 bilayers were less sensitive to calcium and caffeine, but no change in single-channel conductance wa

86 developing type 2 diabetes, independently of caffeine, but since coffee is a complex matrix, consumpt

87 her expression levels of most flavonoid- and caffeine- but not theanine-related genes contribute to t

88 allowed the detoxification of the pulp from caffeine by 50%, while significantly reducing the amount

89 i.e. Theobromine (TB), Theophylline (TH) and Caffeine (C), with application in commercial tea and cof

90 ed lower epigallocatechin gallate (EGCG) and caffeine (ca. 75 and 56%, respectively) compared to bud

91 Dietary caffeine (CAF) is the most commonly consumed psychoactiv

92 on of carbamazepine (CBZ), diclofenac (DCF), caffeine (CAF), and isolithocholic acid (ILA) in wastewa

93 ion in the presence of paracetamol (PAR) and caffeine (CAF).

94 The metabolites trigonelline, caffeine, caffeoylquinic acid and sugars revealed higher

95 molecular basis for mechanism of action; (3) caffeine can continue to exert potent cortical desynchro

96 ken together, these results demonstrate that caffeine can promote BAT function at thermoneutrality an

97 , these data indicate that a trace amount of caffeine can reversibly block the analgesic effects of a

98 d substances were theobromine, theophylline, caffeine, catechin, epicatechin, procyanidins A2 and B2.

99 on and inactivation shifts, following 0.5 mM caffeine challenge.

100 on of three different emerging contaminants (caffeine, ciprofloxacin, and propranolol) and two model

101 Caffeine citrate or placebo until drug therapy for apnea

102 Caffeine citrate therapy for apnea of prematurity reduce

103 Biomarkers of caffeine, citrus, and dietary fiber consumption had stro

104 L-Theanine-caffeine combination improved total cognition composite

105 L-Theanine-caffeine combination may be a potential therapeutic opti

106 L-Theanine-caffeine combination was associated with decreased task-

107 between the 457 children assigned to receive caffeine compared with the 463 children assigned to rece

108 spective of the blood hematocrit, to measure caffeine concentration in normal finger prick samples ob

109 For caffeine concentration, there were significant differenc

110 ld brew coffee is likely not due to 3-CGA or caffeine concentrations considering that most acids in c

111 Caffeine concentrations in cold brew coarse grind sample

112 LC-MS/MS analysis of caffeine concentrations in the generated DPS (12 duplica

113 The grind size did not impact 3-CGA and caffeine concentrations of cold brew samples significant

114 ct finger prick blood sampling, and measured caffeine concentrations show a good agreement with measu

115 , and the caffeic acid, chlorogenic acid and caffeine concentrations were determined by HPLC-DAD.

116 ractice was found on nectar volume, sugar or caffeine concentrations, or pollen production.

117 with lower IOP, and the association between caffeine consumption and glaucoma was null.

118 evaluate the associations between coffee and caffeine consumption and various health outcomes, we per

119 role of systemic caffeine levels in dietary caffeine consumption behavior.

120 esic effects of acupuncture, and controlling caffeine consumption during acupuncture may improve pain

121 Caffeine consumption has been associated with loss of bo

122 d cisplatin for ototoxicity and suggest that caffeine consumption should be cautioned in cancer patie

123 Habitual caffeine consumption was associated weakly with lower IO

124 st (>=232 mg/day) versus lowest (<87 mg/day) caffeine consumption was associated with a 0.10-mmHg low

125 etic predisposition to elevated IOP, greater caffeine consumption was associated with higher IOP and

126 Tea is the world's oldest and most popular caffeine-containing beverage with immense economic, medi

127 However, high caffeine content is limiting its direct application.

128 Drying process did not affect the caffeine content, but influenced levels of some amino ac

129 supplemented with 1% EtPp or HWSn had a low caffeine content.

130 s in terms of their phenolic composition and caffeine content.

131 Congo and maragogype variety showed highest caffeine contents with 6.5 and 6.8mg/gDM.

132 e in 5-caffeoylquinic acid but a decrease in caffeine contents.

133 Ibuprofen, carbamazepine, and caffeine contributed most to the risk quotients.

134 sulfamethoxazole, and meprobamate), and the caffeine degradate 1,7-dimethylxanthine were detected in

135 se findings broaden our understanding of the caffeine degradation mechanism by bacterial enzymes and

136 mer showed highly sensitive interaction with caffeine despite poor selectivity, while the "strongly a

137 injected with a 10 muL aliquot of 10000 ppm caffeine DI-water solution, the microwave detector yield

138 e by the next day, and long-term exposure to caffeine did not alter A1 receptor expression at the acu

139 Here, we demonstrate that caffeine did not interfere with normal retinal vasculari

140 h carbamazepine dominating the base flow and caffeine dominating flood events.

141 ousal induced either by sleep deprivation or caffeine during the sleeping period potentiates light re

142 In contrast, 2 mM caffeine elicited delayed negative shifts in both activa

143 ine stimulated proton secretion, whereby the caffeine-evoked effect was (i) shown to depend on one of

144 We hypothesized that caffeine evokes effects on GAS by activation of oral and

145 Multiple doses of caffeine exacerbated cisplatin ototoxicity which was ass

146 port here that single-dose administration of caffeine exacerbates cisplatin-induced hearing loss with

147 nsible for 90% of caffeine metabolism, while caffeine exerts many of its effects via antagonist bindi

148 showed moderate binding while stevioside and caffeine exhibited low binding.

149 tion of bioactive and drug molecules such as caffeine, Fasudil, and Metyrapone.

150 n the flies' microbial communities; notably, caffeine fed insects displayed higher microbial variabil

151 ssments revealed trigonelline, caffeic acid, caffeine, feruloyl quinic acid, di-caffeoyl quinic acid,

152 rolled in the randomized, placebo-controlled Caffeine for Apnea of Prematurity trial between October

153 Children enrolled in the CAP (Caffeine for Apnea of Prematurity) randomized controlled

154 Caffeine, found in many foods, beverages, and pharmaceut

155 e authors sought to test the efficacy of the caffeine-free version of a popular energy drink compared

156 chemical map of elemental lead and molecular caffeine, from lead nitrate and caffeine residues, was g

157 Caffeine, generally known as a stimulant of gastric acid

158 Fewer children in the caffeine group had values for FVC below the fifth centil

159 Expiratory flows were better in the caffeine group, by approximately 0.5 SD for most variabl

160 n interaction between the CYP1A2 genotype or caffeine-GS and coffee intake with respect to risk of CV

161 CYP1A2 genotype and caffeine-GS were not associated with CVD (P >= 0.22 for

162 or a genetic score for caffeine metabolism (caffeine-GS) modifies the association between habitual c

163 e association varies with CYP1A2 genotype or caffeine-GS.

164 than 1,251 g who were treated with neonatal caffeine had improved respiratory function at 11 years o

165 etermination of paracetamol, tryptophan, and caffeine have not been reported so far, and we report an

166 one (methylone)) or synthetic cathinones and caffeine; however, little is known about whether interac

167 the developed method showed the presence of caffeine in breast milk samples (12-179ng/mL).

168 A reduction in caffeine in coffee leaves and seeds might result in decr

169 Larvae exposed to caffeine in diets showed increased mortality, and larvae

170 protocol was utilized for the estimation of caffeine in different beverages and biological fluids wi

171 rs selectively increase the concentration of caffeine in its monomeric state, but decrease its solubi

172 Together with clinical use of caffeine in neonates, our demonstration of the selective

173 on of 1 ng/mL cocaine in serum and 200 pg/mL caffeine in raw urine, as well as the differentiation of

174 RATIONALE: Caffeine in the newborn period shortens the duration of

175 inearly proportional to the concentration of caffeine in the range of 0.5-20microM with a correlation

176 etermination of paracetamol, tryptophan, and caffeine increased linearly with the increase in concent

177 In contrast, caffeine increased wake time, NREM gamma power, and LMA

178 octurnal rodents, both sleep deprivation and caffeine-induced arousal potentiate the photic entrainme

179 re, stac3(NAM) myofibers exhibited increased caffeine-induced Ca(2+) release across a wide range of c

180 nhibition or siRNA silencing of p38 impaired caffeine-induced Ca(2+) release from wild type cells whi

181 sults in functional channels as indicated by caffeine-induced Ca(2+) release response in HEK293 cells

182 caffeine without significantly affecting the caffeine-induced Ca(2+) transient amplitude, a measure o

183 Moreover, caffeine-induced calcium release yielded no difference b

184 This inhibitory effect of HED on caffeine-induced GAS was verified in healthy human subje

185 Our data suggest that caffeine-induced impairments in postprandial glycaemia a

186 , we demonstrate automated recordings of (i) caffeine-induced-, (ii) electrical field stimulation (EF

187 Caffeine intake (from 80.7 to 85.5 mg/d; P = .57) and le

188 The relationship between caffeine intake and glaucoma was null (P >= 0.1).

189 have investigated paternal and grandparental caffeine intake in relation to offspring outcomes.

190 Maternal caffeine intake is associated with adverse birth outcome

191 ntenatal, but not paternal or grandparental, caffeine intake is associated with higher offspring adip

192 In addition, caffeine intake stimulates attention and vigilance, and

193 Greater caffeine intake was associated weakly with lower IOP: th

194 In adjusted models, maternal caffeine intake was associated with a higher offspring B

195 Caffeine intake was derived from relevant food items in

196 We examined the association of habitual caffeine intake with intraocular pressure (IOP) and glau

197 Risk factors for HGD or EAC included age, caffeine intake, and low-grade dysplasia while colonic a

198 isk factors included age, abdominal obesity, caffeine intake, and the presence of HGD.

199 estionnaires (2009-2012), we evaluated total caffeine intake.

200 were observed for paternal and grandparental caffeine intake.

201 r year 9; per 100 mg/d increment in maternal caffeine intake], WC z-score [beta (95% CI): 0.09 (0.01,

202 Caffeine is a widely consumed psychoactive substance, bu

203 rogenic acids, trigonelline and choline) and caffeine is higher in Arabica coffees.

204 gh VPD conditions during withering increased caffeine levels in Clone 2 and Yabukita, respectively (p

205 irm an important modulating role of systemic caffeine levels in dietary caffeine consumption behavior

206 Caffeine levels originating from blood drops of unknown

207 Caffeine levels steadily increased over time in both cul

208 MDPV, methylone, and caffeine maintained responding in a dose-dependent manne

209 esponse to nonsense suppression therapy, and caffeine may be a useful adjunct to enhance treatment ef

210 r caffeine treatment for apnea suggests that caffeine may protect against ROP.

211 pants rated intensity perception of sucrose, caffeine, menthol and capsaicin solutions.

212 f the CYP1A2 genotype or a genetic score for caffeine metabolism (caffeine-GS) modifies the associati

213 genetic factors contributing to variation in caffeine metabolism and confirm an important modulating

214 P450 1A2 (CYP1A2) is responsible for 90% of caffeine metabolism, while caffeine exerts many of its e

215 s unaffected by genetic variants influencing caffeine metabolism.

216 ohol consumption, coffee consumption, plasma caffeine metabolites or BMI in previous GWAS; none was i

217 , CIAT, glyphosate) and two pharmaceuticals (caffeine, metformin) with detection frequencies ranging

218 otic effects of ethanol, and pretreatment of caffeine might be a strategy to counter the hypnotic eff

219 vulnerability (e.g., marijuana, alcohol, and caffeine misuse, perceived stress, and impulsive behavio

220 The caffeine of one espresso coffee was equivalent to 130 bi

221 This study examined the effect of caffeine on BAT thermogenesis in vitro and in vivo.

222 Caffeine on its own induced no phase shifts.

223 ts of the ryanodine receptor (RyR) modulator caffeine on Na(+) current (I(Na)) activation and inactiv

224 ests potential mechanisms for the effects of caffeine on neuronal cells.

225 A (CYP1A2; rs762551) influence the effect of caffeine on the postprandial glucose (GLU) response to a

226 Caffeine, one identified NMNAT2 positive-modulator, when

227 Following epinephrine and caffeine, only the R67Q(+/-) mice had bidirectional vent

228 by making the ryanodine receptor leaky (with caffeine or ryanodine) or by decreasing sarco/endoplasmi

229 oses of the TAAR1 partial agonist RO5263397, caffeine, or vehicle p.o.

230 ecular pharmaceutical ingredients, including caffeine, paracetamol, ibuprofen, tamoxifen, BAY 11-7082

231 aining coloured melanoidin-rich, sugars- and caffeine-poor fractions from instant coffee, in this wor

232 Caffeine preferentially protects against oxygen-induced

233 on curves indicated that adding 0.5 and 2 mM caffeine prior to establishing the patch seal respective

234 y scores were correlated with high levels of caffeine, protein, chlorogenic acids and total titratabl

235 36); trans-Isoeugenol (PubChem CID: 853433); Caffeine (PubChem CID: 2519); Dicyclohexylmethanol (PubC

236 ed from 1 to 5, SR Ca content (assessed with caffeine pulses) increased, the number of Ca wave initia

237 At the hypoxic phase, caffeine reduced microglial activation and enhanced tip

238 At the hyperoxic phase, caffeine reduced oxygen-induced neural apoptosis by aden

239 The amount of the caffeine released from hydrogel decreased by citrate cro

240 nd molecular caffeine, from lead nitrate and caffeine residues, was generated, demonstrating the comp

241 Isolates with unstable caffeine resistance show cross-resistance to antifungal

242 genes, including some whose mutation confers caffeine resistance.

243 and 4.4 nM for paracetamol, tryptophan, and caffeine, respectively.

244 5-trisphosphate (IP(3))-sensitive stores and caffeine/ryanodine-sensitive stores.

245 homoeriodictyol (HED), a known inhibitor of caffeine's bitter taste.

246 ffect of sugars (mono- and disaccharides) on caffeine self-association and solubility.

247 of concentrations in the absence of altered caffeine sensitivity as well as increased Ca(2+) in inte

248 Caffeine should be used routinely, while corticosteroids

249 , sugars act as selective hydrotropes toward caffeine, since they differentially act on specific solv

250 ulates GAS, whereas oral administration of a caffeine solution delays GAS in healthy human subjects.

251 lysis of data obtained from ingestion of the caffeine solution revealed an association between the ma

252 sampling performances were also verified on caffeine-spiked blood samples in vitro, using both LC-MS

253 1 cells, various bitter compounds as well as caffeine stimulated proton secretion, whereby the caffei

254 SR calcium content was assessed by measuring caffeine-stimulated release.

255 tion guidance pathways that respond to acute caffeine stimulation and suggests potential mechanisms f

256 ce, but little is known about the effects of caffeine stimulation on global gene expression changes i

257 tration of the adenosine receptor antagonist caffeine substantially enhanced the frequency and number

258 n independent and rapid evolution of the tea caffeine synthesis pathway relative to cacao and coffee.

259 s, similar to the nonselective AR antagonist caffeine, taken as the reference compound.

260 The influence was stronger for coffee caffeine than tea caffeine.

261 catechin, epicatechin, epicatechin gallate, caffeine, theobromine and theophylline.

262 d p-coumaric acids) and two methylxanthines (caffeine, theobromine) were studied, according to the pr

263 cessfully detecting three molecular markers, caffeine, theobromine, and theophylline, associated with

264 Drugs (caffeine, theophylline) and hormones (vasopressin, aldos

265 Caffeine therapy for apnea of prematurity did not signif

266 the direct evidence of the novel effects of caffeine therapy in the prevention and treatment of ROP.

267 To evaluate whether neonatal caffeine therapy is associated with improved functional

268 At the doses used in this trial, neonatal caffeine therapy is effective and safe into middle schoo

269 However, caffeine therapy was associated with a reduced risk of m

270 of targeted tidal volume ventilation, use of caffeine therapy, oxygen therapy post-surfactant and inc

271 For efficient sequential degradation of caffeine, these enzymes form a unique heterocomplex with

272 in the lowest IOP PRS quartile consuming no caffeine, those in the highest IOP PRS quartile consumin

273 uced ROP severity in premature infants after caffeine treatment for apnea suggests that caffeine may

274 Caffeine treatment in midnight triggered c-Fos expressio

275 Caffeine treatment in the newborn period improves expira

276 Both sleep deprivation and caffeine treatment potentiated light-induced c-Fos expre

277 Both sleep deprivation and caffeine treatment potentiated light-induced phase delay

278 ht by sleep deprivation (gentle handling) or caffeine treatment that both prevented sleep.

279 , including a history of colonic adenomas or caffeine usage.

280 These effects were abrogated if caffeine was added after establishing the patch seal or

281 cted meta-analyses of observational studies, caffeine was associated with a probable decreased risk o

282 s affected by significant heterogeneity, and caffeine was associated with a rise in blood pressure.

283 nsform infra-red spectroscopy suggested that caffeine was enclosed within the gel network via non-cov

284 NMD inhibition with caffeine was shown to restore CHM mRNA transcripts to ne

285 were the most abundant polyphenols, whereas caffeine was the main methylxanthine (90%).

286 sion of TAS2Rs, including cognate TAS2Rs for caffeine, was shown in human gastric epithelial cells of

287 chin and the methylxanthines theobromine and caffeine were consumed together.

288 3-CGA and caffeine were found at higher concentrations in cold bre

289 onelline, gallic acid, chlorogenic acid, and caffeine were identified, with trigonelline and caffeine

290 These effects of caffeine were mediated by its blockade of A(1)AR, as co-

291 oral and gastric TAS2Rs and demonstrate that caffeine, when administered encapsulated, stimulates GAS

292 This effect was reversed by caffeine, whereby velocity was increased by 11% after ex

293 contains the methylxanthines theobromine and caffeine, which may also affect vascular function.

294 ular molecule used in foods and beverages is caffeine, which, most of the time, is derived from synth

295 Coadministration of caffeine with a low dose of l-DOPA reduces dyskinesia in

296 he oxidation of paracetamol, tryptophan, and caffeine with significant decrease in overpotential due

297 Such interference was reversible, as caffeine withdrawal fully restored the efficacy of acupu

298 e designed for a rapid, on-site detection of caffeine without involving sophisticated instruments or

299 [Ca(2+) ]i rise induced by the RyR activator caffeine without significantly affecting the caffeine-in

300 Caffeine worsened and L-theanine had a trend of worsenin