ライフサイエンスコーパス: cage

1 suspended grow-out systems called 'floating cages'.

2 es using Capped Analysis of Gene Expression (CAGE).

3 y addition and subsequent destruction of the cage.

4 s a previously unattainable, extremely large cage.

5 soluble, flexible Pd(II)(6)L(4) coordination cage.

6 finement within a Pd(II)(6)L(4) coordination cage.

7 pped at two different sites inside the C(82) cage.

8 he incorporation of a large EA cation in the cage.

9 helices, the PAAR domain, and an intact beta-cage.

10 formation of a single enantiopure octahedral cage.

11 s towards targets flexibly positioned in the cage.

12 e air to a susceptible partner in a separate cage.

13 , including a finite-sized three-dimensional cage.

14 anion of 3 with the nido-C(2) B(10) cluster cage.

15 nic-liquid, porous, tetrahedral coordination cage.

16 fluence the behavior of other animals in the cage.

17 te surface of Au(52)Cu(72) forms an extended cage.

18 clusters and a self-assembled metal-organic cage.

19 es low-frequency, phonon-type motions of the cage.

20 ture of stereoisomers of a chiral octahedral cage.

21 lohexanediamine to access low-symmetry imine cages.

22 ats were either stressed or remained in home cages.

23 esign of catalytically active supramolecular cages.

24 f the diffusing molecule between neighboring cages.

25 to atomically-precise hexameric coordination cages.

26 ing energy in terms of monomeric and dimeric cages.

27 torial competition in animals from different cages.

28 sed to design enantiopure Pd(II) tetrahedral cages.

29 ve been observed to be part of the fullerene cages.

30 However, the resulting cage 1 has an uncommon geometry consisting of two triang

31 conducted by substituting Ca by H in a beta-CaGe(2) layered Zintl phase through topochemical deinter

32 hrough the design of a small hemicryptophane cage (3) presenting a southern tris-urea hosting moiety.

33 be the best-suited filament material for the cage 3D printing, and polycaprolactone fibers appeared t

34 re, we synthesized an organic cage molecule (Cage-6-NH(2)) that was used as a triangular prism node t

35 method for enhancing PCR specificity, and we cage a biostable antisense oligonucleotide for time-rele

36 e versatility of this approach by reversibly caging a 2'-O-methylated RNA aptamer as well as syntheti

37 (4)- and (M)(4)-configured alleno-acetylenic cage (AAC) receptors offer a highly defined interior for

38 polyhedral oligomeric silsesquioxane (POSS) cages achieved spherical assemblies of PBIs, instead of

39 d in two cold (~20 K), hydrogen-bonded water cages adopted by the Cs(+).(HDO)(D(2)O)(19) and D(3)O(+)

40 Finally, a system of two cages, adsorbed on to different regions of alumina, stab

41 these large cations occupying the perovskite cages affect the structural, optical, and electronic pro

42 -6 with task-specific anionic porous organic cages affords a porous ionic liquid with anionic porous

43 Injurious home-cage aggression (fighting) in mice affects both animal w

44 The Reach Cage allows systems-level sensorimotor neuroscience stud

45 A sarcophagine cage amine ligand, MeCOSar (5-(8-methyl-3,6,10,13,16,19-

46 dation of a B-B bond between a boron cluster cage and an exopolyhedral boron-based substituent (e.g.,

47 e materials where the ratio between cationic cage and anionic cage is potentially tunable.

48 ctahedral geometry imposed by the perovskite cage and behaves as a heavy atom rattling oscillator.

49 rage, displace one TMAda(+) from occupying a cage and contain predominantly 6-MR isolated Al sites.

50 nation dependence also varied between flight cage and field experiments (-10 to 37% in the same culti

51 formational change upon heating, causing the cage and its cargo to reversibly transfer between aqueou

52 pose that the spatial separation between the cage and the substrate molecule conferred by the extende

53 or "rattling" of K cations inside oversized cages and as well as to twinning, stacking faults and an

54 We describe the synthesis of porous cages and highlight those based on monometallic, bimetal

55 eatments in controlled experiments in flight cages and in the field.

56 for WASp in formation of sequestrating actin cages and maintenance of mitochondrial network integrity

57 b personnel to move the animals between home cages and training chambers, to start and end training s

58 arge states due to significant impact of ion caging and plasma electron screening.

59 microbes affected has been difficult due to 'cage' and 'legacy' effects in model systems.

60 nificantly stretches Pb-I bonds, expands the cage, and induces a larger octahedral distortion in the

61 n Comprehensive Lab Animal Monitoring System cages, and respiratory exchange ratio and activity were

62 out as unable to assemble into high-symmetry cages-and the same aldehyde generates low-symmetry socia

63 riments and cyclic voltammetry show that the cage anodically shifts the redox potential of the encaps

64 pe and the number of redox probes within the cage are useful handles to fine-tune the electron transf

65 resented work features the optofluidic light cage as a novel on-chip sensing platform with unique pro

66 ous ionic liquid with anionic porous organic cages as the anionic parts and 18-crown-6/potassium ion

67 tural complexity of 3D COFs by using organic cages as the building units.

68 We also demonstrate glyoxal caging as an effective method for enhancing PCR specific

69 from the interdimer interface that is key to cage assembly.

70 noncoding genes, as described in the FANTOM CAGE-Associated Transcriptome (FANTOM-CAT) study.

71 s a triangular prism node to yield the first cage-based 3D COF, 3D-CageCOF-1.

72 work represents a novel example of a cyclic cage-based [2]catenane oligomer.

73 The permanent porosity in the cage-based porous liquids has been also confirmed by mol

74 ure of the cue (illuminated lever entry into cage), but some also found the cue to be attractive and

75 figuration (60 x 60 cm2), 54 special housing cages can accommodate 2 to 3 mice each for an approximat

76 t the emissive intensity of the coordination cages can be controlled by restricting the dynamics of A

77 tic interactions are used, the metal-organic cages can be synthesized very fast, homogeneously, and i

78 The B(18)-framework in the Ln(3)B(18)(-) cages can be viewed as consisting of two triangular B(6)

79 Glyoxal caging can also be used to reversibly disrupt enzyme-nuc

80 ed examples point to a poor understanding of cage catalysis in general, limiting the ability to desig

81 we show that a simple, bioinspired synthetic cage catalyzes Michael addition reactions using only Cou

82 mechanism of azobenzene switching inside the cage cavity and explore key molecular factors that may c

83 earch institution with an approximate 60,000 cage census.

84 1/H3K27ac, DNase-seq/ATAC-seq, P300, POLR2A, CAGE, ChIA-PET, GRO-seq, STARR-seq and MPRA).

85 Our cages closely resemble natural polyhedral protein archit

86 -framework streamlines the rapid analysis of cage-clustered-data and promotes the use of 'study-power

87 semble the permanently porous supramolecular cage Co-PB-1(6) bearing six Co-TPP subunits connected th

88 e linkers to amines yields the more flexible cage Co-rPB-1(6).

89 oms encapsulated within truncated octahedral cages composed of alternating carbon and boron atoms.

90 be prohibited even by rigid interconnecting cage compounds such as cubane or diamantane.

91 nes are a venerable class of macrocyclic and cage compounds that often contain unusual conformations,

92 Caging confers complete suppression of gRNA:dsDNA-target

93 nding to synthesise a family of low-symmetry cages containing heteroatoms, illustrating that pores of

94 ray crystallographic analysis shows that the cage contains asymmetrical and nonplanar windows, exhibi

95 ylenedisulfotetramine (TETS) is a so-called "caged" convulsant that is responsible for thousands of a

96 ds in published literature because more mice/cage could be perceived as a strategy to reduce housing

97 crystalline open organics, including organic cages, covalent organic frameworks (COFs), and macrocycl

98 The cage crystals exhibit high iodine vapor uptake (3.78 g g

99 rand, respectively) and a substrate with the caged cytotoxic (monomethyl auristatin E: MMAE; a high-a

100 stem consisting of nanometer-sized inorganic cages, decorated by Bronsted acid sites, in which organi

101 We hypothesized that this high animal-cage-density practice abounds in published literature be

102 and BC concentrations; fathead minnows were cage deployed pre- and post-replacement at sites with va

103 s the stability and pressure lability of the cage, despite its location being discrete from the inter

104 Magnetic stirring action of the cage devices enabled highly efficient interaction of the

105 One cage did not bind guests, whereas the second encapsulate

106 dynamical results from microscopic nanometer cage diffusion over mesoscopic micrometer gradient diffu

107 cannot be accommodated in the cubo-octhedral cage (do not follow the Goldschmidt tolerance factor rul

108 licable to the extensive library of reported cages, enabling new applications based upon selective so

109 cial interaction of groups of mice in a home-cage environment.

110 ates, expanding the volume of the perovskite cage, equivalent to exerting "negative pressure" on the

111 n with rates of ~0.2 ps(-1), thus inhibiting cage escape and photoproduct formation.

112 ncluding cyclical oscillations of the 'dirty-cage/excrement microbiome', we ranked by priority the he

113 Furthermore, SRF delivered by CAGE exhibited significantly different biodistribution c

114 In a large cage experiment, the drive allele successfully spread to

115 We used cage experiments in ponds to test competing hypotheses a

116 activate Cas9 and can drive to completion in cage experiments.

117 ear and factors potentially influencing home-cage fighting were recorded.

118 ximately 60-79%, no toxicity was observed in caged fish, and there were marked decreases in concentra

119 es and in the production of artificial viral cages for bio/nanotechnological applications.

120 ssembly and disassembly of nanoscale protein cages for the capture and internalization of protein or

121 ids, in particular choline and geranic acid (CAGE), for oral delivery of a hydrophobic drug, sorafeni

122 e, Kenya, along with its estimated adult rib cage, for comparison with H. sapiens and the Kebara 2 Ne

123 gh a hydrophobic trimethyl-L-lysine-binding 'cage' formed by BAHCC1(BAH), mediating colocalization of

124 als how subtle structural differences in the cage framework affect binding and catalysis.

125 The assemblies of 7,12-disubstituted cages from 7-(alkyl/aryl) NBDs, as well as the selective

126 d Geranic acid (CAGE) to form a viscoelastic CAGE gel and sandwiched between two layers of a biodegra

127 The rheological properties of the CAGE gel were dominated by the elastic modulus and sugge

128 We have developed a caged glutamate probe that is inert toward these recepto

129 However, all caged glutamates are known to have strong antagonism tow

130 Caged gRNAs are generated by substituting four nucleobas

131 Caged gRNAs are novel tools for the conditional control

132 Photoremovable caging groups are useful for biological applications bec

133 ent photolabile protecting groups, so-called caging groups, onto two different ligands recruiting Von

134 n and aiding the rational development of new caging groups/catalysts for chemical biology and drug-de

135 ate stability inside the GroEL/ES chaperonin cage have not been reported.

136 Finally, T3 cages have been employed in a host-guest study as they o

137 Only a few electrocatalytic reactions within cages have been reported, and there is no information re

138 Different cages have different solubilities, reaction rates, and e

139 Because the two coordination cages have excellent chemical stability in aqueous solut

140 s liquids composed of functionalized organic cages have recently attracted attention.

141 l-organic frameworks and porous coordination cages have shown incredible promise as a result of their

142 of a M(24) L(6) type hexameric coordination cage held together exclusively by trivalent metal ions.

143 gonal chemistry and image tumours in mice by caging hemicyanine with TCO (tHCA).

144 tube test as a model to analyze the within-a-cage hierarchy in male mice, but also as a paradigm of n

145 ne guests within a Pd(II)-based coordination cage host in water.

146 Cage housing enabled simple and robust handling of the f

147 interlocked M(12)L(8) icosahedral nanometric cages (i.e., internal voids of 2500 angstrom(3)).

148 This method of coordination cage immobilization on solid phases is envisaged to be a

149 ow us to characterize the flexibility of the cage in the solvent, the (rare) guest encapsulation and

150 ing of 15-crown-5 and anionic porous organic cages in a 2:1 ratio gives only solids, while the additi

151 eat application potentials of porous organic cages in heterogeneous phase.

152 ctrons in the first two layers of octahedral cages in perovskites are transferred to PT-TPA.

153 formation of flexible, long-lived molecular cages in the bio-polymer matrix of the cell wall that pa

154 itum access to a running wheel in their home cage increased galanin mRNA in the LC of mice, which was

155 Upon oral dosing in rats, CAGE increased peak blood concentrations of SRF by 2.2-f

156 CAGE induced a 7-fold increase in the cumulative insulin

157 racellular calcium oscillations, while other caged inositol pyrophosphates (3,5-(PP)(2)-InsP(4), 5-PP

158 ation of these porous and potentially porous cages into membranes.

159 ect of the dipole-bound (DB) electron on the cage intramolecular complexes does not fit into the stan

160 Whether a low-energy cage is isolated can be correctly predicted from the the

161 t leading to the formation of an enantiopure cage is noteworthy.

162 uantitative dimerization to form a molecular cage is observed.However, attaching three such urazole u

163 the ratio between cationic cage and anionic cage is potentially tunable.

164 n the catalytic properties of porous organic cages is still in an initial stage.

165 functionalized Fe(II) (4) L(4) coordination cage, is grafted with oligoethylene glycol imidazolium c

166 es, such as those provided by supramolecular cages, is quickly gaining momentum.

167 tion is focused on linker chemistry than the cage itself.

168 M yielded enantiopure homochiral tetrahedral cages (LambdaLambdaLambdaLambda)T1 and (DeltaDeltaDeltaD

169 ediately coordinates an amine in the solvent cage, leading to B-pyridinium or B-ammonium boranephosph

170 he key roles of crystal structure and liquid caging length in determining the temperature dependence

171 signaling, and they highlight the utility of caged, light-activated kinases for dissecting stress-act

172 About 50 mg of fibers was placed in a round, cage-like housing consisting of two identical 3D printed

173 microscopy revealed that excitons within the cage-like scaffolds are robust, even under extreme heat

174 y tunable (~4.3-4.9 nm), uniform (+/-0.3 nm) cage-like scaffolds.

175 sional (3D) crystallographic registry within cage-like superstructures emerges as a result of the con

176 We generated photo-caged lipid probes, which allow acute manipulation of di

177 We first construct peptide-caged liposomes that treat protease activity as two-valu

178 Cage loadings are quantified via adsorption isotherms an

179 ing type), genetic background, time of year, cage location on the rack, and rack orientation in the r

180 r (high and moderate) and a control, then we caged locusts on these plants for 2 weeks.

181 ing a kinase with activating mutations and a caged lysine blocking the active site, we can rapidly sw

182 ethanol, alkene, and aromatic species in the cages may substantially slow down or facilitate the diff

183 l imaging and/or behavioral training of home cage mice using Raspberry Pi-based hardware.

184 ds to fast and efficient release of a set of caged model species, conjugated via various linkages.

185 Here, we synthesized an organic cage molecule (Cage-6-NH(2)) that was used as a triangul

186 ) that bear tetrazines (TZ@SWCNTs) and a TCO-caged molecule was used to deliver active effector molec

187 molecular porous liquid formed from organic cage molecules.

188 hing of reactions by the diffusion of excess caging molecules confines synthesis to light patterns an

189 motion (TAM) plot showed the abdomen and rib cage motion in synchrony.

190 Composed of a peptide-caged NIR signaling moiety linked with a hydrophilic pol

191 ed throughout the 5'-protospacer region with caged nucleobases during synthesis.

192 The two coordination cages, NUS-100 and NUS-101, are assembled from the highl

193 ructural model, with one Ca position and the caged O on a 24d special position, being preferred.

194 re, where framework distortions coupled with cage occupants, are correlated to electronic band struct

195 y introducing a stimulus mouse into the home-cage of a singly housed mouse (i.e. the resident/intrude

196 unusual examples of enantiopure tetrahedral cages of square-planar metal ions.

197 e tolerance factor range can still enter the cages of the 2D halide perovskites by stretching them.

198 -nucleic acid interactions, and we show that caging of guide RNA allows for tunable and reversible co

199 ethod for the immobilization of coordination cages on alumina is reported.

200 ne to accept up to two electrons to form the cage-opened dianionic nido-C(2)B(10) cluster core.

201 kes place in a two-step process: barrierless cage opening followed by Coulomb repulsion-driven fragme

202 carborane, resulting in C-C bond rupture and cage opening.

203 ble) protecting groups (PPGs), also known as caged or photocaged compounds, are used to enable non-in

204 Photolabile chelating cages or protecting groups need complex chemical synthes

205 f using silicone rubber passive samplers and caged organisms (Ruditapes philippinarum), simultaneousl

206 environment was replicated using a molecular cage, Pd(6)(TPT)(4) (TPT = 2,4,6-tri(pyridin-4-yl)-1,3,5

207 five-step total synthesis of arborisidine, a caged pentacyclic monoterpene indole alkaloid, has been

208 ithin porous molecular space, porous organic cages (POCs) have been the most widely reported over the

209 his drive was able to spread through a large cage population in just six generations following introd

210 lly be substituted within Type-VII clathrate cages, presenting opportunities for a large family of bo

211 tes from antibody-drug conjugates (ADCs) and caged prodrugs.

212 Both Co-PB-1(6) and Co-rPB-1(6) cages produce 90-100 % H(2) O(2) from electrochemical OR

213 The anion-stabilizing property of the cage promotes spontaneous pro-nucleophile deprotonation,

214 We propose that PAAR and the beta-cage provide distinct structures that promote secretion.

215 CAGE provided excellent apparent solubility of SRF tosyl

216 orphyrin affords a porphyrin tubular organic cage, PTC-1(2H).

217 Mutant strains lacking Cagalpha, Cagbeta, or CagE (putative ATPases corresponding to VirB11, VirD4, a

218 dices including phase angle ( ), percent rib cage (RC %), breaths per minute (BPM), and labored breat

219 ce, and the molecular phenotype, measured by CAGE, recapitulated the observed cellular phenotypes whi

220 The performance of the light cage related to absorption spectroscopy, refractive inde

221 hereas final social status acquired within a cage remains unaffected.

222 tion of surface areas for these coordination cages reported over the past three years.

223 Catenated cages represent chemistry's challenging synthetic target

224 to [8 Fe:21 Zn:12 protomers], these protein cages represent some of the compositionally most complex

225 The present cages represent unusual examples of enantiopure tetrahed

226 owing divergence from the canonical aromatic-cage residues to accommodate large substrates.

227 ion of solubilizing addends to the fullerene cage results in a large number of isomers, which are gen

228 acement assays demonstrate that the adsorbed cages retain the ability to encapsulate and separate gue

229 Here, we developed a caged RNA strategy that allows Cas9 to bind DNA but not

230 utual orientation of two BODIPY units in the cage's cavity was remarkably similar to that in the crys

231 The cage's microenvironment also promotes high diastereosele

232 ced formation of the other enantiomer of the cage selectively.

233 h fighting had skin injuries observable from cage-side.

234 ession comparisons with aneuploid cells, the CAGE signature is no longer evident in aneuploid cells.

235 We show that the CAGE signature is not an aneuploidy-specific gene-expres

236 g yeast cells mount the ESR, rather than the CAGE signature, in response to aneuploidy-induced cellul

237 and the "common aneuploidy gene-expression" (CAGE) signature, in which many ESR genes are oppositely

238 reveals that the incorporation of EA in the cage significantly stretches Pb-I bonds, expands the cag

239 Mechanistic studies revealed that SRF-CAGE solution spontaneously formed a self-assembled stru

240 ramework hosting K(+) ions inside polyhedral cages, some of which are reminiscent of known clathrate

241 This indicates a major cage-stabilizing role for heme within this family of fer

242 However, synthetic supramolecular cages still lack comparable complexity to reach the high

243 Quantum chemistry studies show that the cage structure contains rare intramolecular hydrogen-hyd

244 The formation of DB anions with the cage structure has principal features, controlled not on

245 eptide repeats, which fold into a large beta-cage structure that encapsulates the C-terminal toxin do

246 The molecular cage structure was also characterized by FTIR, NMR, and

247 tes in the distorted pentagonal dodecahedron cage structure.

248 the capacity of boron to form fullerene-like cage structures.

249 Mutational analysis of this aromatic cage supports its role in conferring specificity for the

250 Thanks to the versatile and orthogonal cage surface modifications, we show how this approach ca

251 are coordinated to the three Ln atoms on the cage surface.

252 where metal atoms are integral parts of the cage surface.

253 hydrophobic residues including F229, forms a cage surrounding a Xe mimic of CO.

254 about 6% of transcribed enhancers defined by CAGE-tag analysis are associated with CGIs.

255 troduce the concept of the optofluidic light cage that allows for fast and reliable integrated spectr

256 characterization of a macrocyclic polyamide cage that incorporates redox-active 1,4-dithiin units.

257 allenges for the preparation of coordination cages that are soluble and stable in water.

258 ly larger lattice parameter allowing for the cages that result from the framework arrangement to expa

259 anocages, whereas in the central part of the cages the solvent is highly disordered.

260 Such cages thus show promise in biological, medical, environm

261 ncaging properties displayed by two coumarin-caged thymidine compounds, each conjugated with (2) or w

262 Furthermore, comparing the CCS of a ferritin cage to the solution structures in the PDB reveals signi

263 sectional heating and cooling allow for the cage to traverse multiple phase boundaries, allowing for

264 self-assembling architectures, from protein cages to extended two-dimensional (2D) and three-dimensi

265 he use of choline-geranic acid ionic liquid (CAGE) to enhance its dermal penetration.

266 ILs/DES made from Choline and Geranic acid (CAGE) to form a viscoelastic CAGE gel and sandwiched bet

267 very short time dynamics of the ballistic to caged transition.

268 Small cage trials show that single releases of gene-drive male

269 and full introduction was observed in small cage trials within 6 to 10 generations following a singl

270 bjects were freely flying within transparent cages two meters from the optical system; a proof-of-pri

271 s n(tot) = 0.085x V(p) - 0.013x V(p) (2) for cage-type MOFs and n(tot) = 0.076x V(p) - 0.011x V(p) (2

272 c bands: one band (RC) placed around the rib cage under the upper armpit and another band (AB) around

273 Orientational correlations between cage units increase with increasing layer number control

274 eby different cargoes could be moved between cages using acid and base as chemical stimuli.

275 The probes are reversibly caged vasodilators that induce responses detectable by h

276 Housing system (the combination of cage ventilation and bedding type), genetic background,

277 Cage ventilation and rack orientation often cannot be ch

278 Supramolecular cages/vesicles in biology display sophisticated structur

279 a library of five Co(II) L(A) (x) L(B) (4-x) cages was formed in a statistical ratio in the absence o

280 A subset of cages was sampled over the course of a year and factors

281 minal-depth cap analysis of gene expression (CAGE), we quantified transcriptional activity of both ho

282 the imine bond dynamics of covalent organic cages, we studied the formation and exchange of both dia

283 Cagalpha and CagE were required for H. pylori-induced NF-kappaB activ

284 onance guidance was observed while the light cages were immersed in an aqueous environment.

285 Approximately 14% of group-housed male cages were observed with fighting animals in brief behav

286 When the building blocks of both cages were present during self-assembly, a library of fi

287 generates low-symmetry socially self-sorted cages when combined with a linear aldehyde.

288 on increase of the addition numbers to C(80) cage, which is favored for accommodating the Gd atoms of

289 Reduction of the cage window size by chemical synthesis switches the sele

290 wn to be taken up by the liquid coordination cage with an affinity that increased with their size.

291 A novel low-symmetry organic molecular cage with distinctive geometry was successfully synthesi

292 Females were caged with male mice.

293 ghly stable zirconium(IV)-based coordination cages with aggregation induced emission (AIE) molecular

294 havioral observations, but only 14% of those cages with fighting had skin injuries observable from ca

295 s the spectroscopic signatures of the parent cages with increased gas uptake capacities as compared t

296 had no effect on an established hierarchy in cages with mixed genotypes, both Galphai2(-/-) and contr

297 es for the design and synthesis of molecular cages with novel topologies targeting a broad range of a

298 and triamines of two different [2 + 3] imine cages with the aid of a deuterated dialdehyde molecular

299 s the number of cations that can enter their cages without destabilizing their overall structure.

300 ystems, synthetic water-soluble coordination cages (WSCCs) can isolate guest molecules and host chemi