ライフサイエンスコーパス: calcify

1 lular immune reaction and ova (viable and/or calcified).

2 ion length was 8.3 cm, and 44% were severely calcified.

3 luded; 30 (25.2%) were moderately or heavily calcified.

4 lying plaque type (lipid: 0.63+/-1.23 mm(2); calcified: 0.81+/-1.44 mm(2); and fibrous: 1.20+/-1.52 m

5 uted tomography (CT) lesion was described as calcified (24x22x17.5 mm), connected with posterior leaf

6 Approximately 38% of parenchymal cysts calcify after antiparasitic treatment.

7 structed coral reef communities comprised of calcified algae, corals, and reef pavement that were ass

8 e has been profound interest in the study of calcifying algae, because of their important role in the

9 -cell impedance spectroscopy in the field of calcifying algae.

10 in ocean acidification, which is a threat to calcifying algae.

11 considered to be globally the most dominant calcifying algal species, which creates a unique exoskel

12 mRNA expression levels were evaluated in 9 calcified and 8 normal aortic valves by RNA sequencing.

13 Additional prespecified endpoints were non-calcified and calcified plaque measures and high risk pl

14 The difference in cell density between calcified and decalcified cells can explain the differen

15 at using opacity we can discriminate between calcified and decalcified coccolithophores with an accur

16 low pH, whole colonies found at low pH site calcified and extended their skeleton at the same rate a

17 Affymetrix Human Transcriptome 2.0 arrays in calcified and noncalcified aortic valve tissue from 58 p

18 omas was analyzed by whole-mount staining of calcified and noncalcified human aortic valves, obtained

19 UHR CT improves visualization of calcified and stented vessels but may result in increase

20 rare cause of coronary thrombosis in highly calcified and tortious arteries in older individuals.

21 s, whereas others allow treatment of heavily calcified and tortuous segments.

22 d plaque (NCP), low-density NCP (NCP<30 HU), calcified and total plaque volumes, and corresponding pl

23 at extreme warm temperatures but continue to calcify and grow.

24 hich instead decreases with acidification in calcifying and noncalcifying species.

25 ular mechanisms of biomineralisation in both calcifying and silicifying haptophytes remain poorly und

26 ization pattern known from other unicellular calcifying and silicifying organisms.

27 se To assess the relationship between total, calcified, and noncalcified coronary plaque burdens thro

28 ed as the absolute annual increase in total, calcified, and noncalcified plaque volume by quantitativ

29 areader agreement rates were high for total, calcified, and noncalcified plaques for both CT scanners

30 r stent expansion and the presence of large, calcified, and/or attenuated plaques were independent pr

31 initial loss of calcium was less in heavily calcified aortas and was associated with an increase in

32 To address this, calcified aortas from uremic mice were transplanted orth

33 ingeal arterial calcifications, necrotic and calcified areas in basal ganglia, dentato-olivary dyspla

34 Calcified areas of GA cross-linked tissue showed charact

35 Perl iron-positive signals colocalized with calcified areas or osteoblast-like cells in human vascul

36 hat neointimal hyperplasia is accelerated in calcified arteries and that this may be due in part to i

37 Neointimal cell proliferation in calcified arteries as assessed by proliferating cell nuc

38 Treatments aimed at inhibiting restenosis in calcified arteries may differ from those that work in un

39 also observed ectopic expression of FGF23 in calcified arteries of alpha-kl(-/-) mice, which might ac

40 In calcified arteries, bone morphogenetic protein 2 (BMP-2)

41 Bicuspid aortic valves calcify at a significantly higher rate than normal aorti

42 Thus, patients with a comparable calcified atherosclerosis burden generally carry a simil

43 althy animal arteries and ~0.1 micromolar in calcified atherosclerotic arteries owing to slower tissu

44 Coronary artery calcified atherosclerotic plaque (CAC) predicts cardiova

45 nosis and can mimic arterial dissection, non-calcified atherosclerotic plaque and intraluminal thromb

46 tive value beyond its association with total calcified atherosclerotic plaque burden as assessed by c

47 Here we revealed that CPB isolated from calcified atherosclerotic plaques and artificially synth

48 g Symbiodinium spp. in culture commonly form calcifying bacterial-algal communities that produce arag

49 with a tailored screening approach; that non-calcified baseline lung nodules greater than 300 mm(3),

50 mineral nanoparticles have been detected in calcified blood vessels, the nature and role of these pa

51 d bone tissue and the vasculature within the calcified bone matrix.

52 ows for rapid, simultaneous visualisation of calcified bone tissue and the vasculature within the cal

53 rapidly cleared all tested organs, including calcified bone, but the fluorescence of proteins and imm

54 anslocate Ca(2+) out of osteoblasts into the calcifying bone matrix.

55 ensory system in the premaxilla and a partly calcified braincase, which potentially refines estimates

56 P2 depletion and increased cytosolic Ca(2+), calcified CaM N lobe interacts with helix B in place of

57 e, we reveal the competition of PIP2 and the calcified CaM N lobe to a previously unidentified site i

58 tal growth with pronounced chamber dilation, calcifying cardiomyocyte necrosis, aseptic inflammation,

59 TE and TT were not associated with calcified carotid plaques in either sex.

60 focused on the intervening tissue, articular calcified cartilage (ACC) and its role in the initiation

61 There were large discrete areas of calcified cartilage in the hypertrophic zone, few signs

62 tic mice also exhibited an elevated ratio of calcified cartilage to total articular cartilage (CC/TAC

63 gnificantly reduced OARSI scores and CC/TAC (calcified cartilage to total articular cartilage), but i

64 subchondral bone turnover and hypertrophy in calcified cartilage, yet additional mechanical or metabo

65 rs of hypertrophic chondrocytes in articular calcified cartilage.

66 act loaded joints and to explore the role of calcified-cartilage stiffness on the biomechanics of hea

67 ed infection and EhV production, even though calcified cells and associated coccoliths had significan

68 V infection, were generally more abundant in calcified cells and enriched in purified, sorted coccoli

69 is without qualification generally refers to calcifying chronic pancreatitis.

70 y, known as opacity, to discriminate between calcified coccolithophores and coccolithophores with a c

71 algae, including the ecologically important calcifying coccolithophores, Emiliania huxleyi and Scyph

72 lankton, such as the silicifying diatoms and calcifying coccolithophores, plays an important role in

73 Certain stony corals can alternate between a calcifying colonial form and noncalcifying solitary poly

74 ave suggested a worse prognosis after PCI of calcified compared with noncalcified lesions.

75 cromolecules interact with the intracellular calcifying compartment (coccolith vesicle) through the c

76 cular smooth muscle cells (SMCs) grown under calcifying conditions , stimulation with BMP-2 significa

77 gher calcium deposition induced by prolonged calcifying conditions by inhibiting osteogenic different

78 Cells incubated with calcitriol under calcifying conditions specifically maintained expression

79 reased calcification of VSMCs in response to calcifying conditions.

80 this did not occur in those grown under non-calcifying conditions.

81 Calcifying coralline macroalgae provide biogenic habitat

82 gae, conferring a competitive advantage over calcifying corals and coralline algae.

83 These well-preserved visual organs comprise calcified corneal lenses that are separated by interveni

84 compared with SR coronary CT angiography of calcified coronary artery lesions, suggesting a potentia

85 and animal calcification models and in human calcified coronary artery.

86 Optimal plaque preparation of calcified coronary lesions is key to prevent stent failu

87 Patients with calcified coronary lesions were screened in 3 centers.

88 strategy for lesion preparation in severely calcified coronary lesions with high success rate, low p

89 an important interventional tool for heavily calcified coronary lesions.

90 n interventional cardiology for treatment of calcified coronary lesions.

91 my (CA) can be utilized in treating severely calcified coronary lesions; however, the temporal trends

92 associated with an increased progression of calcified coronary plaque and a reduced progression of n

93 Although age and sex distributions of calcified coronary plaque have been well described in th

94 We examined the distributions of NCP and calcified coronary plaque in healthy 30- to 74-year-old

95 Atorvastatin reduced non-calcified coronary plaque volume relative to placebo: me

96 hores, uses carbon to photosynthesize and to calcify, covering their cells with chalk platelets (cocc

97 In human aortic valves, calcified cusps were stiffer and had more collagen depos

98 h metals was not inherent to intracellularly calcifying cyanobacteria but was likely a genetically ba

99 lly silent, a proportion of individuals with calcified cysticerci develop seizures from these lesions

100 safety and effectiveness of IVL in severely calcified de novo coronary lesions.

101 oup A) primary IVL therapy for patients with calcified de-novo lesions (n=39 lesions), (group B) seco

102 cient DNA from five specimens of Neanderthal calcified dental plaque (calculus) and the characterizat

103 Historic calcified dental plaque (dental calculus) can provide a

104 Calcified dental plaque (dental calculus) preserves for

105 nt a small group of malformations containing calcified dental tissues of both epithelial and mesenchy

106 eby Vn plays an active role in orchestrating calcified deposit formation.

107 anic nanoparticles are found not only within calcified deposits but also in areas devoid of microscop

108 We show that (18)F-NaF adsorbs to calcified deposits within plaque with high affinity and

109 re is no evidence for discrepancies in ss-sl calcifying depth habitat or seasonality in the Gulf of M

110 V) (OR, 1.34; 95% CI, 1.04-1.73; P = 0.023), calcified drusen (OR, 1.33; 95% CI, 1.04-1.72; P = 0.025

111 4.24; P = 0.023), the complement pathway and calcified drusen (OR, 3.75; 95% CI, 1.79-7.86; P < 0.001

112 additionally associated with the presence of calcified drusen (P = 5.38 x 10(-6)).

113 l periodontitis in adolescents is the partly calcified, dysbiotic bacterial biofilm, which interacts

114 However, the in situ sensitivity of calcifying ecosystems to future ocean acidification rema

115 Calcified eggshells protect developing embryos against e

116 tic acid (EDTA) that were designed to target calcified elastic lamina when administrated by intraveno

117 The formation of the calcified endoskeleton of the sea urchin embryo is a val

118 ls can be further modulated with time by the calcified environment, thus contributing to the age-depe

119 a benign skin appendage tumor, also known as calcifying epithelioma, consists of islands of epithelia

120 ue, these proteins are not restricted to the calcifying epithelium, suggesting that they also play ot

121 ependent enrichment of annexins 2, 5 or 6 in calcifying EVs posits one of several emerging factors im

122 diesterase 3 expression and the secretion of calcifying exosomes from VSMCs in vitro, and chemical in

123 l-sphingomyelinase2 (nSMase2) to release pro-calcifying exosomes.

124 ontrolling the amount and the quality of the calcified extracellular matrix.

125 r, the mechanisms that regulate formation of calcifying extracellular vesicles remain obscure.

126 eries of events involving the aggregation of calcifying extracellular vesicles, and the formation of

127 ly the close association of macrophages with calcified fibers.

128 s increases-which is relevant to bone and to calcified fibrotic tissues, including diseased muscle.

129 at, P. cylindrica up-regulated the pH of its calcifying fluid (pHcf approximately 8.4-8.6), with each

130 0) for calcification rates or the pH of the calcifying fluid (pHcf); the latter was derived from bor

131 norganic carbon (DIC) concentration of their calcifying fluid above that of seawater.

132 control on the extent of pH elevation in the calcifying fluid and explain most of the observed inter-

133 ragonite saturation state (Omegaarag) in the calcifying fluid by elevating pH while at the same time

134 The fact corals actively regulate their calcifying fluid chemistry implies the potential for acc

135 sus seawater conditions in controlling coral calcifying fluid chemistry.

136 attachment may occur from the supersaturated calcifying fluid known to exist in corals, or from a den

137 odel quantitatively reproduces variations of calcifying fluid pH in natural Porites colonies, and pre

138 cts an average 0.16 unit decrease in Porites calcifying fluid pH, i.e., ~43% increase in H(+) concent

139 n pumping, carbon influx and the exchange of calcifying fluid with external seawater, contributes to

140 3(2-)] and pH from the gastric cavity to the calcifying fluid, confirming the existence of a proton (

141 controls on the carbonate chemistry of their calcifying fluid, implying a high degree of resilience t

142 d pH (-0.05 units) and [CO(3)(2-)] within GA calcifying fluid.

143 esence of some internal echogenic debris and calcified foci in their dependent part.

144 mental conditions and predation impacts in a calcifying foundation species.

145 s (SITs) are present in both silicifying and calcifying haptophyte phytoplankton, including some glob

146 Emiliania huxleyi is a calcifying haptophyte, contributing to both the organic

147 in biomineralisation in both silicifying and calcifying haptophytes.

148 The calcified, hard-shelled dinosaur egg evolved independent

149 indirect effects of ocean acidification on a calcifying herbivore (gastropod) within the natural comp

150 positive influence on the abundance of some calcifying herbivores, which can overwhelm any direct ne

151 uld be triggered by resuspension of healthy, calcified host cells in an EhV-free, 'induced media'.

152 DRP1 protein was observed in calcified human aortic valves, and DRP1 RNA interference

153 scopic analyses of both the hydrogels and of calcified human plaques, we demonstrate that calcific mi

154 ied media of human femoral artery tissue and calcified human valves.

155 l three genes was significantly decreased in calcifying human bone osteosarcoma (SaOs-2) cells.

156 Cortical remodeling, limb isometry, and thin calcified hypertrophic metaphyseal cartilages indicate a

157 al environment become relatively more highly calcified, implying a positive climatic feedback.

158 2% and 0.6% glutaraldehyde (GA), and further calcified in vitro to simulate graft calcifications upon

159 rigid substrates, with pretreated xenografts calcifying in vivo to a similar extent as native bone.

160 Except for the optical system, as in the calcified lenses of trilobite and ostracod arthropods, o

161 er in nonanatomical resection and suspicious calcified lesions in hepatoduodenal ligament were also r

162 -related vascular remodeling and presence of calcified lesions in PAH remain unexplored.

163 p B) secondary IVL therapy for patients with calcified lesions in which noncompliant balloon dilatati

164 safety of intravascular lithotripsy (IVL) in calcified lesions of an all-comers cohort.

165 Mean diameter stenosis of calcified lesions was 71.8+/-13.1% at baseline, decrease

166 Seventy-eight calcified lesions were treated using the Shockwave C(2)

167 4), and 19 additional patients with severely calcified lesions were treated with DA+DCB.

168 Patients with PAH display features of calcified lesions within the distal pulmonary arteries (

169 A+DCB, 81.3% for DCB (P=0.78), and 68.8% for calcified lesions.

170 y facilitated stent implantation in severely calcified lesions.

171 or part of the mitral annulus, with markedly calcified margins, and no significant impact on the valv

172 that drove the preferential loss of heavily calcified marine biota.

173 This may be especially important for calcified marine herbivores, such as the pinto abalone (

174 Calcified marine organisms typically experience increase

175 We cultured a globally important calcifying marine plankter (the foraminifer, Globigerina

176 ped for the effect of decreasing ocean pH on calcifying marine species assemblages can also be used f

177 trabeculae, loss of osteocytes, presence of calcified marrow, and elevated expression of osteocalcin

178 od vessels in bone are deeply encased in the calcified matrix, imaging techniques that are applicable

179 expression of androgen receptor (AR) in the calcified media of human femoral artery tissue and calci

180 ty, PPV, NPV, and accuracy of hyperdense non-calcified mediastinal and hilar lymph nodes, known as "b

181 lular matrix (ECM) proteins, secreted to the calcifying medium [3-6], which appear to provide the nuc

182 carbonate extracellularly as aragonite in a calcifying medium between the calicoblastic ectoderm and

183 Interestingly, while individual polyps calcified more and extended faster at low pH, whole colo

184 /-) mice, these mice neither accumulate dead calcified myofibers nor lose ambulation.

185 aces helices A and B with the apo C lobe and calcified N lobe, respectively.

186 ntly higher adsorption coefficients than non-calcified (naked) cells.

187 ed increase in apoptotic chondrocytes in the calcified nasal septum.

188 nd timing of PE episodes in individuals with calcified NCC are variable and commonly chronic, sometim

189 % of the patients with recurrent seizures in calcified neurocysticercosis (NCC).

190 ial prevention and treatments of symptomatic calcified neurocysticercosis (NCC).

191 The calcified nodule has been suggested as a rare cause of c

192 usp retraction, stiffening, and formation of calcified nodules.

193 rders of the exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms.

194 are embedded within a matrix that is heavily calcified on the nanoscale.

195 ve a detrimental effect on the physiology of calcifying organisms [3].

196 exposure hotspots, suboptimal conditions for calcifying organisms encompassed up to 56% of the summer

197 fy the effect of acidification on planktonic calcifying organisms has relied on laboratory based stud

198 Calcifying organisms have exhibited reduced calcificatio

199 will disproportionately impact the growth of calcifying organisms in coral reef ecosystems.

200 osition of minerals, but their importance in calcifying organisms is poorly understood because it is

201 from within these acidic pools are devoid of calcifying organisms, and channel structures among the p

202 model will be relevant for many other marine calcifying organisms, and that it can be used to improve

203 OA), which is of particular significance for calcifying organisms, including planktonic coccolithopho

204 is predicted to impact ecosystems reliant on calcifying organisms, potentially reducing the socioecon

205 e indirect effects of ocean acidification on calcifying organisms, which may counter or exacerbate di

206 idification is expected to negatively impact calcifying organisms, yet we lack understanding of their

207 marine systems, and is especially harmful to calcifying organisms.

208 state and threatening the survival of marine calcifying organisms.

209 ting to the development of proliferative and calcified PA lesions.

210 atures, diagnosis, and management of chronic calcifying pancreatitis, focusing on pain management, th

211 ition are the major risk factors for chronic calcifying pancreatitis.

212 importance of E. huxleyi as a bloom-forming, calcifying, photoautotroph, E. huxleyi-EhV interactions

213 cale have the potential to negatively impact calcifying plankton, which play a key role in ecosystem

214 -related risk of CHD (CASR), coronary artery calcified plaque (PTPRN2), and kidney function (CDH23, H

215 Calcified plaque at the proximal stent edge (relative ri

216 for uptake was significantly associated with calcified plaque burden (P < 0.0001) and cardiovascular

217 Tracer uptake was compared with calcified plaque burden and cardiovascular risk factors.

218 coronary plaque characteristics and overall calcified plaque burden confer an increased risk of coro

219 orded in 188 (47%), any plaque in 214 (53%), calcified plaque in 151 (38%), and noncalcified/mixed pl

220 supplements and measures of subclinical CVD (calcified plaque in the coronary artery, carotid artery,

221 These data illustrate that calcified plaque limited intravascular drug delivery, an

222 respecified endpoints were non-calcified and calcified plaque measures and high risk plaque features

223 However, statin therapy reduced non-calcified plaque volume and high-risk coronary plaque fe

224 Calcified plaque was negatively associated with efaviren

225 es were higher in patients with CAV, whereas calcified plaque was not (median 0.0 vs 0.0, P = .510).

226 re of noncalcified and calcified plaque, and calcified plaque were significantly higher among men wit

227 cified plaque, a mixture of noncalcified and calcified plaque, and calcified plaque were significantl

228 t or supplements with any of our measures of calcified plaque, and no greater mortality risk was obse

229 alyzed separately: CAC score >0, any plaque, calcified plaque, noncalcified/mixed plaque, segment inv

230 re negatively associated with any plaque and calcified plaque, respectively.

231 o human peripheral arteries with substantial calcified plaque.

232 abetes mellitus mainly led to an increase in calcified plaque.

233 ndent association with annual progression of calcified plaque.

234 f coronary artery calcium, mixed plaque, and calcified plaque; higher CCL2 levels were associated wit

235 ) and of any plaque; noncalcified, mixed, or calcified plaque; or stenosis on coronary CT angiography

236 ; 95% CI, 0.15-0.85) and more often had only calcified plaques (38% versus 16%; ORadjusted=3.57; 95%

237 aled fewer mixed plaques and more often only calcified plaques among athletes, suggesting a more beni

238 raphy showed a better agreement with ICA for calcified plaques compared with SR coronary CT angiograp

239 of HRM (defined as noncalcified or partially calcified plaques) in the LMCA.

240 with fewer mixed plaques and more often only calcified plaques.

241 Total plaque index (calcified plus noncalcified plaque) was defined as plaqu

242 ves (n = 52) dissected into noncalcified and calcified portions were subjected to mRNA extraction, re

243 plicated in the regulation of EV release and calcifying potential.

244 CT angiography revealed a large partially calcified pseudoaneurysm arising from the right lateral

245 ant of (14)C-labeled, declining 5.5-fold per calcified quadrant (p=0.05, n=7).

246 Multivariable analysis identified calcified raphe and excess leaflet calcification (define

247 Calcified raphe and excess leaflet calcification were as

248 Both calcified raphe plus excess leaflet calcification were f

249 xposed four common CCA genera and a crustose calcifying red algae, Peyssonnelia (collectively CCRA) f

250 ing mediator resolvin E1 was dysregulated in calcified regions and acted as a calcification inhibitor

251 Compared with noncalcified portions, calcified regions exhibited elevated transcripts for CD8

252 METHODS AND DRP1 was enriched in calcified regions of human carotid arteries, examined by

253 entify degrees of cross-linking and detected calcified regions with high chemical specificity, an abi

254 higher in noncalcified regions compared with calcified regions.

255 ting their persistence and that of their non-calcifying relatives under impending global warming and

256 wever, challenging lesions, such as severely calcified, remain difficult to treat with DCB alone.

257 ally resolve and either disappear or leave a calcified scar that is associated with seizures.

258 establish, and eventually resolve, leaving a calcified scar.

259 Mean calcified segment length was 47.9 +/- 18.8 mm, calcium a

260 The calcifying shell is an excellent model for studying biom

261 ey may require more energy to maintain their calcified shells and acid/base balance with ocean acidif

262 rate, higher salinity regimes, thicker, more calcified shells with a higher aragonite (nacreous layer

263 oach to localize a single component within a calcified skeleton.

264 ts rapid onset and also because many pelagic calcifying species (including 100% of ammonites and more

265 data on the effects of acidified seawater on calcifying species growth, reproduction, and survival.

266 abundance with elevated CO2 whereas obligate calcifying species, and non-calcareous macroalgae whose

267 y enhancing calcium carbonate dissolution of calcifying species.

268 ing biological uptake and incorporation into calcified structures and, second, that scales may repres

269 Calcified structures such as otoliths and scales grow co

270 he balance between these fates, as occurs in calcifying tendinopathies associated with aging.

271 deregulated BMP signaling, and spontaneously calcifying tendons in young CLOCKDelta19 arrhythmic mice

272 is a lethal orphan disease in which infants calcify the internal elastic lamina of their medium and

273 brae was reduced by 35%, the strength of the calcified tissue (sigmamax) was proportionate to a 38% i

274 reased in calcified tissue compared with non-calcified tissue and C-allele carriers exhibited increas

275 thickness were reduced, the weakening of the calcified tissue and the geometric component of strength

276 nally, docosahexaenoic acid was decreased in calcified tissue compared with non-calcified tissue and

277 llusc shells (and indeed to any invertebrate calcified tissue).

278 xplained by the location of the magnesium in calcified tissue.

279 s regulate the onset of mineral formation in calcifying tissues is not well established.

280 acterise structural remodelling in soft (non-calcified) tissues and to conduct in situ studies of nat

281 In vitro, Runx2(f/f) SMCs calcified to a much greater extent than those derived fr

282 e tissue secretes proteins and minerals that calcify to form a new incremental layer of the exoskelet

283 tection of treatment response because of the calcified tumor matrix.

284 ave a greater number of OESs, whereas larger calcified tumors have larger OES diameter.

285 of her left eye white, prominent, partially calcified tumour 1 disc diameter in diameter, 1,5 disc d

286 associated with higher FADS2 mRNA levels in calcified valve tissue, whereas FADS1 mRNA and other tra

287 rval [2.1-2.9]; P < 0.0001) in patients with calcified valves (12 +/- 3% at 20 years) relative to the

288 /4) were obtained in 251 patients (80%) with calcified valves and 661 (93%) with noncalcified valves

289 pression levels of RUNX2 were upregulated in calcified valves and associated with eQTL-SNPs.

290 YKL-40 expression in calcified valves and in an experimental pressure overloa

291 In the 251 patients with calcified valves who had good immediate results, 15-year

292 dependent calcium channel was upregulated in calcified valves.

293 igand bound to microcalcifications formed by calcifying vascular smooth muscle cell derived extracell

294 nase complex phosphorylation is increased in calcifying vascular smooth muscle cells (VSMCs) and in c

295 The presence of no plaques or purely calcified versus noncalcified plaques, plaque volume acc

296 vascular smooth muscle cells (VSMCs) and in calcified vessels of patients with atherosclerosis, sugg

297 ification have modestly improved outcomes in calcified vessels, adverse event rates are still high.

298 Sortilin localized to calcifying vessels in human and mouse atheromata and par

299 The mechanical properties of this calcified weapon enable extremely powerful punches to be

300 Mammalian tissues calcify with age and injury.