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1 These actions require activation of calcineurin phosphatase.
2 of the Ca2+/calmodulin-dependent phosphatase calcineurin (phosphatase 2B) increases the frequency, bu
4 OS generation also blocked TGF-beta-mediated calcineurin phosphatase activity and decreased ECM accum
5 Foxo1 or Foxo3 in cardiomyocytes attenuates calcineurin phosphatase activity and inhibits agonist-in
6 t with these results, Foxo proteins decrease calcineurin phosphatase activity and repress both basal
8 rom steroid receptors mediate an increase in calcineurin phosphatase activity by steroid hormones.
9 is therefore concluded that AngII stimulates calcineurin phosphatase activity in proximal tubule epit
10 D2HG, but not L2HG, inhibited Ca2+-dependent calcineurin phosphatase activity in stimulated Jurkat ex
11 that were sufficient to inhibit 90% of total calcineurin phosphatase activity in the hypertrophied my
14 gulated kinase (ERK) kinase activity but not calcineurin phosphatase activity is required for LPS-sti
15 lcineurin-NFAT interaction without affecting calcineurin phosphatase activity may be useful as therap
21 promoter, up-regulated RCAN1 mRNA, inhibited calcineurin phosphatase activity, and exerted a striking
22 posed to cyclosporin A (CsA), which inhibits calcineurin phosphatase activity, failed to develop norm
23 ation at nanomolar potency without impairing calcineurin phosphatase activity, nuclear factor-kappaB
25 ease from intracellular stores and increased calcineurin phosphatase activity, resulting in NFATc1 nu
31 utamate receptors, intracellular Ca(2+), and calcineurin-phosphatase activity, but not the broad-rang
34 ly ablate the main regulatory subunit of the calcineurin phosphatase complex in B cells to reveal bot
35 sely, a mutant with constitutively activated calcineurin phosphatase demonstrated decreased azole sen
36 ds on the NFI phosphorylation state and that calcineurin phosphatase dephosphorylates and activates N
37 el TRPC1 and involves Ca2+ signaling through calcineurin phosphatase for SSH activation and growth co
38 uch as cyclosporine A (CsA), an inhibitor of calcineurin phosphatase, frequently develop similar meta
41 Aquaporin 2 (AQP2), a putative substrate of calcineurin phosphatase in the kidney, is also involved
44 bilization, and pretreatment of cells with a calcineurin phosphatase inhibitor prevented the spontane
46 -IgM-induced cell death in B104 cells by the calcineurin phosphatase inhibitor, cyclosporin A, abroga
48 odels of chronic rejection, its synergy with calcineurin phosphatase inhibitors, and its inhibitory e
49 lls and inhibited by cell treatment with the calcineurin phosphatase inhibitors, cyclosporine (CsA) a
50 encodes a transcription factor regulated by calcineurin phosphatase; its disruption enhanced azole s
52 ce with a beta-cell-specific deletion of the calcineurin phosphatase regulatory subunit, calcineurin
54 in 1 (RCAN1), an endogenous inhibitor of the calcineurin phosphatase that is triplicated in Down synd
55 calcium signals is largely mediated through calcineurin phosphatase, the inhibition of IL-12 product
56 es dephosphorylation by the calcium-mediated calcineurin phosphatase to promote NFAT nuclear accumula
57 alcineurin-interacting protein that inhibits calcineurin phosphatase when overexpressed, often upregu
58 epsilon The effect of PKC is not mediated by calcineurin phosphatase, which is known to evoke the cal