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1 in which activates CaMKII in the presence of calcium.
2 ANXA2), with high affinity at high levels of calcium.
3 f small foci of intracranial hemorrhage from calcium.
4 rupting the mutant thin filament response to calcium.
5 milarly tightened by buffering intracellular calcium.
8 shots of ryanodine receptor type 1 (RyR1), a calcium-activated calcium channel engaged in the binding
9 Purkinje-cell-specific knockout (KO) of the calcium-activated K+ channel SK2 (L7-SK2) show intact ve
11 Among the altered genes, an increase of the calcium-activated potassium channel Kcnn2 in the motor c
15 g two-photon microscopy to monitor astrocyte calcium and electrocorticogram to record neuronal networ
16 justing for potential confounders, including calcium and fiber intake (P for trend = 0.03), and were
17 association between admission serum ionized calcium and in-hospital AKI, with nadir in-hospital AKI
19 of reactive oxygen species on mitochondrial calcium and mitochondria-dependent apoptosis in cardiac
21 t is widely hypothesized that an increase in calcium and reactive oxygen species activate a large con
22 ulate metabolism and ATP production, such as calcium and reactive oxygen species, are also key regula
23 ns, micro- and macronutrients, milk contains calcium and the insulin-like growth factor-1 that are of
25 In order to study the bioavailability of calcium and vitamin D(3), the W/O/W double emulsions wer
26 lcified segment length was 47.9 +/- 18.8 mm, calcium angle was 292.5 +/- 76.5 degrees , and calcium t
29 ing oil core mode particles contained, e.g., calcium as well as agglomerated soot mode particles.
30 activity of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in cardiac myocytes is modulated
31 ATP-powered calcium pump (secretory pathway calcium ATPase 1 [SPCA1]) encoded by the ATP2C1 gene in
32 horylates sarcoplasmic/endoplasmic reticulum calcium-ATPase 2a (SERCA2a) and accelerates calcium re-u
33 imulations, we demonstrate that cbEGF domain calcium binding decreases under mechanical stress (i.e.
34 response to environmental stresses, in their calcium binding properties, and in their conformational
35 evelopmental stages of other markers such as calcium binding proteins and neuropeptides, helped the i
36 Secretagogin (SCGN) is a recently discovered calcium-binding protein belonging to the group of EF-han
38 ng genes for calcium management (calmodulin, calcium-binding proteins), pH regulation (V-type proton
40 receptor signaling, while mutagenesis of the calcium-binding site abolishes Gpr126 function in vivo.
41 stretch-elicited X-ROS primes intracellular calcium (Ca(2+) ) channels for synchronized activation i
42 ted insulin secretion (GSIS) is regulated by calcium (Ca(2+) ) entry into pancreatic beta-cells throu
45 nisms that control mobilization of cytosolic calcium [Ca(2+)](i) are key for regulation of numerous e
47 ther, these results show that the binding of calcium-calmodulin to the C-terminus has long-range allo
48 estigations, we show that in the presence of calcium-calmodulin, the distance across the two GluN1 su
50 mut(PG1)JPH2 overexpressing myocytes caused calcium/calmodulin-dependent kinase II activation and al
51 pgef2 allele with a cre mouse line driven by calcium/calmodulin-dependent kinase IIalpha promoter als
52 The model predicted new crosstalks between calcium/calmodulin-dependent pathways and upstream signa
54 Using Raman microspectroscopy, amorphous calcium carbonate (ACC) was observed first in the drops,
55 calcium oxalate crystals (CaOx) or amorphous calcium carbonate cystoliths are spread among most photo
59 in we report our full investigation into the calcium catalyzed generation and trapping of N-acylimini
60 In the pancreas, excessive intracellular calcium causes mitochondrial dysfunction, premature zymo
62 ial (AP) prolongation (~50%), reduced L-type calcium channel (LCC) current (~33%), reduced outward po
65 , either beta-blockers or nondihydropyridine calcium channel blockers are reasonable drugs in patient
70 otal firing and the ictal increase of T-type calcium channel-mediated burst firing of thalamocortical
73 ions in the significant set of voltage-gated calcium channels among CNVs called from both exome seque
74 at the alpha2delta2 subunit of voltage-gated calcium channels negatively regulates axon growth and re
75 e of TRPV4 channels, which are transmembrane calcium channels that can regulate vascular tone, in mod
78 CaMKII were previously shown to bind L-type calcium channels, and we show here that Shank3 also bind
79 P, an auxiliary subunit of voltage-dependent calcium channels, promoted alpha6beta4 surface expressio
80 including glutamate receptors, voltage-gated calcium channels, the dopamine D2 receptor, and compleme
81 icity, and increased selectivity for Mn over calcium compared with two established Mn ionophores, cal
83 Caco-2 cells treated with the chelate at calcium concentrations of 0-10 mM exhibited enhanced abs
85 oft X-ray microscopy we imaged intracellular calcium-containing particles in the PMCs and acquired Ca
86 in apo state (lacking calcium), whereas in a calcium-containing solution it is stuck in an intermedia
87 cells expressing the C674S mutant, basal SR calcium content was decreased by 31% and the H(2)O(2)-st
89 ked AF-type [Ca(2+)](Nuc) changes and L-type calcium current decreases versus 1-Hz-paced cardiomyocyt
91 ellar glia and granule cells and fired large calcium currents, measured with the genetically encoded
96 tivation in the axonal bouton by PKC-induced calcium-dependent phosphorylation at Ser-41 (pGAP-43).
100 ficantly increased tissue mineralization and calcium deposition at the tissue-implant interface in re
101 ose of P(i) led to a significantly increased calcium deposition, phenotypic change and sEV secretion
104 ned by calcium-sensing proteins that trigger calcium dynamics in response to calcium fluctuations.
106 ysosome contacts in regulating mitochondrial calcium dynamics through the lysosomal calcium efflux ch
108 drial calcium dynamics through the lysosomal calcium efflux channel, transient receptor potential muc
112 rall categorical and essential agreement for calcium-enhanced gradient agar diffusion were 73.7% and
113 hese results support a scenario in which the calcium-enriched oyster environment triggers IamP-mediat
115 uired Ca(2+) flux through the store-operated calcium entry (SOCE) pathway and accompanied plasma memb
116 that CFTR dysfunction in platelets increased calcium entry though the transient receptor potential ca
121 between bioelectric ion channel activity and calcium, finding that cell hyperpolarization and depolar
122 granule neurons, along with bioluminescence, calcium FLIPR, and short hairpin RNA-based gene-silencin
123 signalling network underlying the cytosolic calcium fluctuations are hitherto not fully understood.
125 ptor signaling, but mediated by an increased calcium flux and calcineurin-mediated dephosphorylation
128 actant synthesis is triggered by a sustained calcium flux upon contact with necrotic tissue that requ
129 el 6 (TRPC6) reduced platelet activation and calcium flux, and reduced lung injury in CF mice after i
131 xin-1 (CCL11)-mediated eosinophil migration, calcium flux, cell polarization, and ERK1/2 activation,
132 evolution of intracellular and extracellular calcium fluxes during a single beat which is away from h
138 ry (SOCE) is important in the maintenance of calcium homeostasis and alterations in this mechanism ar
139 suggests that dysregulation of mitochondrial calcium homeostasis is also related to tau and other ris
140 vement of endoplasmic reticulum-mitochondria calcium homeostasis with hepatic HAX-1 inactivation sugg
142 zo1-dependent control of shear flow sensing, calcium homeostasis, cytoskeletal dynamics and pressure-
146 neurons of the lateral OFC using two-photon calcium imaging and investigated how OFC dynamically int
148 r and flow in individual brain microvessels, calcium imaging and optogenetics allow the investigation
150 vation was evaluated by c-Fos expression and calcium imaging at one minute after the anesthetic admin
153 We develop methods for stable hindbrain calcium imaging in free-moving mice, which show that per
156 d natural scene representation, we performed calcium imaging of excitatory neurons in the primary vis
161 of visual cortical areas, we used two-photon calcium imaging to characterize the effects of juvenile
162 combine adaptive optics ophthalmoscopy with calcium imaging to optically record optogenetically rest
163 question by combining whole-brain volumetric calcium imaging using light-field microscopy and an oper
172 l (Cav1.2) antagonist that directly inhibits calcium influx and smooth muscle contractility, leading
175 during associative conditioning to integrate calcium influx resulting from acetylcholine stimulation
179 Near-infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs) can provide advant
181 izing optical calcium imaging, which records calcium ion flux indicating occurrence of an action pote
183 Herein, we used the biologically relevant calcium ion to investigate the conformation of monomeric
185 e treated these podocytes temporarily with a Calcium Ionophore and facultatively with Latrunculin A,
190 s for improving fruit firmness, but elevated calcium levels in grape cells were shown to reduce total
193 ogical response and a normalization of serum calcium levels, confirming the hypothesis of a calcitrio
195 say to quantify the plant-available pools of calcium, magnesium and potassium and trace the soil phas
196 entral to calcification, including genes for calcium management (calmodulin, calcium-binding proteins
198 e introduce rsCaMPARI, a genetically encoded calcium marker engineered from a reversibly switchable f
200 The combination of hard (titanium) and soft (calcium) metals in the heterometallic nodes of MUV-10(Ca
205 ch is linked to an increase in intracellular calcium oscillation mediated by ryanodine receptor (RyR)
206 Carbon-calcium inclusions (CCaI) either as calcium oxalate crystals (CaOx) or amorphous calcium car
208 h as otters, dolphins and ferrets, that form calcium oxalate, struvite, uric acid, cystine and other
209 udied Zn(2+) inhibition of AMPARs by varying calcium permeability, auxiliary subunits, and activation
210 gous mutations in the gene encoding TRPM3, a calcium permeable ion channel, were identified as the ca
211 pecifically, we hybridized the cryogels with calcium peroxide microparticles to controllably produce
213 ube induced microstructural phase changes of calcium phosphate (CP) leading to the formation of brush
215 defects in sheep using 3D-printed customized calcium phosphate scaffolds with or without surgical vas
218 host Golgi compartment-resident ATP-powered calcium pump (secretory pathway calcium ATPase 1 [SPCA1]
219 acutely stimulate the sarcoplasmic reticulum calcium pump (SERCA) by relieving its inhibition by PLN.
222 lacking sperm-specific calcineurin (PP2B), a calcium regulated phosphatase, in testis and sperm, are
223 Moreover, expression of the c-di-GMP and calcium-regulated, biofilm-promoting brp exopolysacchari
224 reveal distinct differences in intracellular calcium regulation and excitation-contraction (EC) coupl
225 The transform between neural activity and calcium-related fluorescence involves nonlinearities and
227 0% (P<0.001, n=18), and promoted spontaneous calcium release activity (n=14, P<0.013) in human cardia
230 ms that are responsible for the pathological calcium release, regarding the tissue origin of the arrh
231 h bursts of action potentials, we found that calcium responses have the capacity to encode action pot
232 eral PAR-2 polarization, suggesting that the calcium responses originated from nonciliated cells.
233 accompanied by actin-Rho dependent growth of calcium rich axonal spheroids that eventually rupture, r
234 d femoral plaque volume; and coronary artery calcium score (CACS) at baseline and 2.8 years later.
235 in, we review the use of the coronary artery calcium score as a decision aid in individuals with type
237 ompared with those without uptake (change in calcium score, 97 [39-166] versus 35 [7-93] AU; P<0.0001
239 ry artery, thoracic aorta, and cardiac valve calcium scores and pulse wave velocity were not signific
241 for calcium homeostasis, TRPV5 and TRPV6 are calcium-selective channels belonging to the transient re
242 Luminal calcium levels are determined by calcium-sensing proteins that trigger calcium dynamics i
247 rall activity, accelerates the refinement of calcium signaling and excitatory inputs without affectin
248 i2 as a potential intermediary between early calcium signaling and subsequent tissue regeneration.
249 one hand, specific Ship1 inhibition enhanced calcium signaling and thereby abrogated an anergic respo
253 podocytes become sensitized to AngII-induced calcium signaling upon injury might explain results from
254 dy indicate a role for endoplasmic reticulum calcium signaling via calreticulin in the differentiatio
255 les in ATP production, metabolic regulation, calcium signaling, generation of reactive oxygen species
256 tion) triggered increased microglial process calcium signaling, often concomitant with process extens
258 tored activation of the Galpha(q/11)-coupled calcium-signaling pathway, beta-arrestin recruitment, an
261 t various stages, including somatic spiking, calcium signals at somata and axons, and striatal dopami
262 the responsiveness of CaMKII holoenzymes to calcium signals can be tuned by varying the relative lev
264 suggest that precise control of ionic flux (calcium, sodium, and potassium) contributes to in utero
265 ase in response to caffeine and the troponin-calcium stabilizer tirasemtiv, similar to responses meas
266 ed to a phase transformation to an anhydrous calcium sulfate, anhydrite, which was formed via repreci
268 Overall, the meta-analysis indicates that calcium supplementation does not provide clinically impo
270 e 1 strong recommendation for baseline serum calcium testing, 13 conditional recommendations, and 1 b
272 ng a mathematical model, that dissolution of calcium that has aggregated within the mitochondria of v
273 lcium angle was 292.5 +/- 76.5 degrees , and calcium thickness was 0.96 +/- 0.25 mm at the site of ma
275 mor microenvironment (TME) by sustaining the calcium transients and neurotransmitter-dependent commun
277 l somata and processes exhibited spontaneous calcium transients in a chronic window preparation.
278 m photon count required for the detection of calcium transients in GCaMP6s-expressing neurons for 920
280 astrocytes respond to neurotransmitters with calcium transients stimulating the release of gliotransm
283 s the hypothesis that impaired mitochondrial calcium transport contributes to the pathogenesis of Bar
284 es involved in cellular transport, including calcium transporters and cytoskeletal regulators, that a
285 oxidation as a consequence of mitochondrial calcium uniporter complex (MCUC) inhibitory subunit MCUb
286 minimal functional unit of the mitochondrial calcium uniporter complex in metazoans, a highly selecti
291 rial compared progression of coronary artery calcium volume score and other measurements of cardiovas
293 pared with placebo attenuated progression of calcium volume score in the aortic valve (14% [95% CI, 5
295 e, calcification grade in raphe, and leaflet calcium volume were assessed with CT analysis in a maske
296 nteraction between 25(OH)D3 and magnesium or calcium was assessed by investigating 1) joint compared
299 mation is pH-sensitive in apo state (lacking calcium), whereas in a calcium-containing solution it is
300 me quercetin derivatives was also favored by calcium, while other flavonols and flavan-3-ols were aff