ライフサイエンスコーパス: calcium channel

1 calcium-handling genes (eg, SERCA2a, L-type calcium channel).

2 interaction with the mechanosensitive piezo calcium channel.

3 th the orthologue of an R-type voltage-gated calcium channel.

4 YetJ/TMBIM6 is a pH-dependent, voltage-gated calcium channel.

5 TRPM7 is not a store-operated calcium channel.

6 s by targeting BK channels and their coupled calcium channels.

7 on dendritic calcium spikes involved R-type calcium channels.

8 mechanism in Ca(V)1 and Ca(V)2 voltage-gated calcium channels.

9 activation and enhanced expression of N-type calcium channels.

10 ding CACNA1A, encoding for neuronal P/Q-type calcium channels.

11 during voltage activation of L-type Ca(v)1.3 calcium channels.

12 mplexes, as well as voltage-gated sodium and calcium channels.

13 ct independent of V2R or verapamil-sensitive calcium channels.

14 ting the function of pre-synaptic UNC-2/CaV2 calcium channels.

15 ransients due to strong expression of T-type calcium channels.

16 ion of Gbetagamma subunits and activation of calcium channels.

17 -dependent manner and binds to voltage-gated calcium channels.

18 ter the cytosol mostly through voltage-gated calcium channels.

19 opening of different types of voltage-gated calcium channels.

20 rol of transcription by AT1R, integrins, and calcium channels.

21 alcin, mostly driven by N-type voltage-gated calcium channels.

22 This is the case for voltage-gated calcium channels.

23 ic reticulum with opening of plasma membrane calcium channels.

24 graded manner, due to recruitment of T-type calcium channels.

25 t can bind and modulate L-type voltage-gated calcium channels.

26 kine receptors and calcium release-activated calcium channels.

27 n-contraction coupling and voltage-dependent calcium channels.

28 ed to abnormal inactivation of voltage-gated calcium channels.

29 s due to Ca(2+) influx through voltage-gated calcium channels.

30 as only partially dependent on voltage-gated calcium channels.

31 ning of NMDA receptors and voltage dependent calcium channels.

32 on their tight association with presynaptic calcium channels.

33 eptors and regulators, and voltage-dependent calcium channels.

34 ers adrenergic modulation upon voltage-gated calcium channels.

35 of alpha2delta1 and alpha2delta3 subunits of calcium channels.

36 -adrenergic agonists stimulate voltage-gated calcium channels.

37 ect of LITAF on Cav1.2 (L-type voltage-gated calcium channel 1.2) channel expression, surface biotiny

38 ergic augmentation of Ca(V)1.2 voltage-gated calcium channels(1-4).

39 in females, whereas in males, either L-type calcium channel activation or calcium release from store

40 Both forms of plasticity rely on T-type calcium channel activation to confer synapse specificity

41 Thus, unbalanced calcium channel activity is a presynaptic mechanism to c

42 pha-interaction domain of the cardiac L-type calcium channel (AID-TAT) on restoring mitochondrial met

43 c glutamate receptor 6 and voltage-dependent calcium channel alpha1.4, are not detected until fetal w

44 new tools to investigate the trafficking of calcium channel alpha2delta subunits.

45 ions in the significant set of voltage-gated calcium channels among CNVs called from both exome seque

46 alpha(2)delta subunits modulate calcium channels and are emerging as regulators of brain

47 alcium source experiments showed that L-type calcium channels and calcium release from internal store

48 veform controls the opening of voltage-gated calcium channels and contributes to the driving force fo

49 ctivation and inactivation of the underlying calcium channels and correctly identified the accepted m

50 its calcium influx through voltage-dependent calcium channels and dampens adrenergic signaling, there

51 tioning was mediated by L-type voltage-gated calcium channels and is consistent with computational ac

52 of trajectories recorded from voltage gated calcium channels and phospholipid anchored GFP in the ce

53 We investigated impacts of calcium channels and purinoceptors on neuronal different

54 s stochastic simulation of individual L-type calcium channels and ryanodine receptor channels, spatia

55 that the C. elegans SHN-1/Shank binds L-type calcium channels and that increased and decreased shn-1

56 We show that the coupling strength between calcium channels and the exocytosis calcium sensor at in

57 act upon glucose transporters, potassium and calcium channels, and G-protein-coupled receptors to mod

58 compartment were dependent on voltage-gated calcium channels, and somatic and nuclear calcium respon

59 CaMKII were previously shown to bind L-type calcium channels, and we show here that Shank3 also bind

60 on magnified levels of calcium (from NMDAR, calcium channels, and/or internal release from the smoot

61 ng the effect of the well-established L-type calcium channel antagonist nimodipine.

62 ia the AC3I peptide and diltiazem, an L-type calcium channel antagonist.

63 um (21.30 nmol/L) and P/Q-type voltage-gated calcium channel antibodies (220 pmol/L).

64 Our results indicate that T-type calcium channels are critical regulators of a C. elegans

65 CaV1 L-type calcium channels are key to regulating neuronal excitabi

66 pression, such as CaMKII, Shank3, and L-type calcium channels, are often mutated in multiple neuropsy

67 scillatory calcium signals via voltage-gated calcium channels as a key component.

68 These findings identify Ca(v)3.1 calcium channels as a molecular target to regulate autop

69 We define T-type calcium channels as a target of Abeta-NgR signaling, med

70 anodine receptors and plasma membrane L-type calcium channels as druggable targets to intercept mitoc

71 implications, with a focus on voltage-gated calcium channels as part of the disease process and as a

72 have been insufficient to engage the target calcium channels associated with neuroprotective effects

73 d support a rationale for gene therapies for calcium-channel-associated cerebellar disorders.

74 , which organizes both synaptic vesicles and calcium channels at the active zone.

75 identify two proteins, the voltage-dependent calcium channel auxiliary subunit BARP and the unfolded

76 The alpha(2)delta-1 subunit of voltage-gated calcium channels binds to gabapentin and pregabalin, med

77 The APD and L-type calcium channel biophysical properties were further asse

78 Calcium channel blockade and MEK inhibition could preven

79 Calcium channel blockade by nifedipine reduced primiR-19

80 re and after additional impairment (from the calcium channel blocker amlodipine).

81 s well as marked acute BP sensitivity to the calcium channel blocker amlodipine.

82 Here we report that felodipine, an L-type calcium channel blocker and anti-hypertensive drug, indu

83 econtamination following a potentially toxic calcium channel blocker ingestion (1D); 2) as first-line

84 ent of ureteral relaxation, we show that the calcium channel blocker nifedipine and the Rho-kinase in

85 rovide a management approach for adults with calcium channel blocker poisoning.

86 In this national cohort study, preadmission calcium channel blocker therapy before sepsis developmen

87 Patients who responded to calcium channel blocker therapy had metabolic profiles s

88 commendations for the stepwise management of calcium channel blocker toxicity.

89 ients with sepsis, of which, 19,742 received calcium channel blocker treatments prior to the admissio

90 The association between calcium channel blocker use and sepsis outcome was deter

91 Prior calcium channel blocker use is associated with reduced m

92 nsidering large baseline differences between calcium channel blocker users and nonusers, a propensity

93 Use of calcium channel blocker was associated with a reduced 30

94 onotoxin CVIE, a potent and selective Cav2.2 calcium channel blocker with proposed antinociceptive ac

95 uretic, usually thiazide-like, a long-acting calcium channel blocker, and a blocker of the renin- ang

96 Nifedipine, a calcium channel blocker, most robustly ameliorated the m

97 ial treatment of systemic corticosteroid and calcium channel blocker, remarkable improvement was noti

98 Instead of its known function as an L-type calcium channel blocker, we found that amlodipine is abl

99 ccepted mechanism of action of nifedipine, a calcium-channel blocker clinically used in patients with

100 (aOR 2.02, CI 1.03-3.96) and dihydropyridine calcium channel blockers (aOR 1.91, CI 1.03-3.55) were a

101 Calcium channel blockers (CCB) improve TB treatment outc

102 ionally, intake of oral hypoglycemic agents, calcium channel blockers (CCB), insulin, and diuretics w

103 Calcium channel blockers (CCBs) are an important class o

104 cancer risk associated with long-term use of calcium channel blockers (CCBs) or angiotensin-convertin

105 erting enzyme inhibitors, beta-blockers, and calcium channel blockers (CCBs) were identified.

106 termine the association between prior use of calcium channel blockers and the outcome of patients adm

107 , either beta-blockers or nondihydropyridine calcium channel blockers are reasonable drugs in patient

108 Experimental studies suggest that calcium channel blockers can improve sepsis outcome.

109 coding insect specific sodium, potassium and calcium channel blockers for their ability to improve th

110 Use of calcium channel blockers has been found to improve sepsi

111 This study determines whether the use of calcium channel blockers is associated with a decreased

112 Moreover, antiepileptics and calcium channel blockers may provide repurposing opportu

113 ensity-matched cohort (20.2% vs 32.9% in non-calcium channel blockers users; p = 0.009) and in multiv

114 Prior use of calcium channel blockers was associated with improved 30

115 The non-dihydropyridine calcium channel blockers were significantly inferior to

116 blockers, beta-blockers, thiazide diuretics, calcium channel blockers, and metformin.

117 beta-Blockers, calcium channel blockers, and mineralocorticoid receptor

118 giotensin receptor blockers, dihydropyridine calcium channel blockers, and non-dihydropyridine calciu

119 um channel blockers, and non-dihydropyridine calcium channel blockers, in the absence of comorbid ind

120 e inhibitors, angiotensin-receptor blockers, calcium channel blockers, or beta blockers) was signific

121 m as it did not replicate for beta-blockers, calcium channel blockers, or diuretics.

122 s and the inferiority of non-dihydropyridine calcium channel blockers.

123 ith sepsis were analyzed, 18.6% of whom used calcium channel blockers.

124 mpared with patients who have never received calcium channel blockers.

125 nt for differential likelihoods of receiving calcium channel blockers.

126 Studies suggest that dihydropyridine calcium-channel blockers may be associated with reduced

127 for AMI; whereas angiotensin-II-antagonists, calcium-channel blockers, angiotensin-converting-enzyme

128 ngiotensin-receptor blockers, beta-blockers, calcium-channel blockers, or thiazide diuretics and the

129 Calcium channel blocking curtailed the enhanced insulin

130 have studied the regulation of voltage-gated calcium channels by MDIMP, which disrupts excitation-con

131 in the alternatively spliced exon 8A of the calcium channel Ca(v)1.2.

132 ric risk gene that encodes the voltage-gated calcium channel Ca(V)1.2.

133 t of the pre-synaptic neuronal voltage-gated calcium channel Ca(v)2.2/N-type, crucial for SNARE-media

134 sence of a splice isoform of a voltage-gated calcium channel (Ca(V)1.3) in the pigeon inner ear that

135 Voltage-gated sodium (Na(V)) and calcium channels (Ca(V)) form targets for calmodulin (Ca

136 d with presynaptic ribbons and voltage-gated calcium channels (Ca(V)1.3).

137 bystander neurons, as were the voltage-gated calcium channel Cacophony (Cac) and the mitogen-activate

138 el current amplitude of native voltage-gated calcium channels can be resolved accurately despite cond

139 Mutations in pre-synaptic voltage-gated calcium channels can lead to familial hemiplegic migrain

140 autoregulation mechanisms and voltage-gated calcium channels can maintain overall renal blood flow a

141 d calcium modulator 1 but also voltage-gated calcium channel (Cav) 1 channels.

142 Here we show that the voltage-gated calcium channel CaV1.3 and the big conductance calcium-a

143 ns, only otoferlin interacts with the L-type calcium channel Cav1.3, showing a significant difference

144 The CACNA1C-encoded cardiac L-type calcium channel (Cav1.2) is essential for cardiocyte act

145 influx through the voltage-dependent L-type calcium channel (CaV1.2) rapidly increases in the heart

146 L-type voltage-gated CaV1.2 calcium channels (CaV1.2) are key regulators of neuronal

147 P binds the mRNA of the R-type voltage-gated calcium channel Cav2.3 in mouse brain synaptoneurosomes

148 translational regulator of the voltage-gated calcium channel Cav2.3 under basal conditions and follow

149 er release is principally mediated by CaV2.1 calcium channels (CaV2.1) and is highly dependent on the

150 d drug mibefradil, which inhibits the T-type calcium channel Cav3.2.

151 ied Flunarizine - a well-known anti-migraine calcium channel (CC) blocker - being able to diminish in

152 associated vesicles and reduced presynaptic calcium-channel clustering.

153 of the JCI, Yang et al. focus on the L-type calcium channel complex (LTCC), and their findings requi

154 odomains, organized by multi-subunit CatSper calcium channel complexes, are pivotal for sperm migrati

155 ve SNc neurons differ substantially in their calcium channel composition and efficacy of excitatory i

156 e, SNc neurons differ substantially in their calcium channel composition, which may contribute to the

157 devices to enable light-inducible gating of calcium channels, conformational switch, dynamic protein

158 Here, we recorded the voltage-gated calcium channel current in nucleated patches from layer

159 espond most sensitively to changes in L-type calcium channel current.

160 impractical because of the rapid rundown of calcium channel currents.

161 The present study found that L-type calcium channel-dependent LTP in the CA3-CA1 hippocampal

162 cular switch that either opens or closes the calcium channel depending on cellular calcium levels.

163 kinase, internal calcium stores, and L-type calcium channels differ between the sexes.

164 ) demonstrate that Ca(v)2-type voltage-gated calcium channels do not mediate presynaptic assembly.

165 receptor type 1 (RyR1), a calcium-activated calcium channel engaged in the binding of ligands.

166 CatSper is a sperm-specific, pH-sensitive calcium channel essential for hyperactivated motility an

167 functionally coupled to, and localize near, calcium channels, ethanol may mediate its behavioral eff

168 Recent experiments have shown that L-type calcium channels exhibit circadian rhythms in both expre

169 uction in cacophony, a Type II voltage-gated calcium channel, expression and that genetically restori

170 The dominant role of Ca(V)2 voltage-gated calcium channels for driving neurotransmitter release is

171 elopment, auxiliary alpha2delta3 subunits of calcium channels foster presynaptic release of GABA, tri

172 shows how a non-linear dependence of T-type calcium channel gating on GABA(B) receptor activity regu

173 sion activity in a RBFOX2-target, the L-type calcium channel gene, Cacna1c.

174 cardiomyocyte calcium flux and expression of calcium channel genes Atp2a2 and Ryr2.

175 h encodes the Ca(v)1.2 isoform of the L-type calcium channel, have been implicated in both PTSD and h

176 Inhibiting high-voltage-activated calcium channels (HVACCs; Ca(V)1/Ca(V)2) is therapeutic

177 showing the more specific activity on L-type calcium channels, i.e. A7r5 (IC50 = 0.18 +/- 0.02 and 0.

178 onstrated that the anti-L-type voltage-gated calcium channel immunoglobulin G purified from patients

179 Inborn errors of CACNA1A-encoded P/Q-type calcium channels impair synaptic transmission, producing

180 pharmacological inhibition of low-threshold calcium channels, implicated as a genetic risk factor fo

181 ORAI1 is a calcium channel in the plasma membrane (PM).

182 ole, from fruit flies to mammals, for L-type calcium channels in augmenting motoneuron excitability.

183 al downregulation of voltage-activated (Cav) calcium channels in DMV neurons, which led to a reductio

184 ess localization and function of L-type like calcium channels in motoneurons.

185 Voltage-dependent sodium and calcium channels in pain-initiating nociceptor neurons a

186 luR2) signaling, which acts on voltage-gated calcium channels in SACs, selectively restricts cross-se

187 timating numbers of functional voltage-gated calcium channels in the membrane and the size of channel

188 drenergic receptors and modulation of T-type calcium channels in the thalamus and was not due to LC m

189 (ATP) channels, opening of voltage-dependent calcium channels, increased [Ca(2+)](i), which triggers

190 Surprisingly, we observed calcium channel-independent effects on microglia, result

191 nodine receptor but not in the voltage-gated calcium channel, indicating that these phenotypes are ca

192 e show that the increased activity of T-type calcium channels induced by the injury plays a major rol

193 uggest that the increased activity of T-type calcium channels induced by the injury plays a primary r

194 sed activity of low voltage activated T-type calcium channels induced by the injury sustains the bulk

195 ducing the action potential duration through calcium channel inhibition.

196 We observe that the calcium-channel inhibitor Rad(8,9), a monomeric G protei

197 tly charged cationic derivative of an N-type calcium channel-inhibitor.

198 ose-dependent effect of L-type voltage gated calcium channel inhibitors on synchronous firing pattern

199 dulation of LTCC; however, a CaVbeta2-CaV1.2 calcium channel interaction is now shown to be required.

200 ial (AP) prolongation (~50%), reduced L-type calcium channel (LCC) current (~33%), reduced outward po

201 unctions of axonal and dendritic L-type like calcium channels likely operate synergistically to maxim

202 trate that Dmca1D (Cav1 homolog) L-type like calcium channels localize to both the somatodendritic an

203 und to regulate low-voltage-activated CaV3.2 calcium channels localized to the axon initial segment,

204 L-type calcium channel (LTCC) current (I(Ca,L)) was measured us

205 n Ca(2+) influx through voltage-gated L-type calcium channels (LTCC) and NFAT translocation to the nu

206 L-type voltage-gated calcium channels (LTCCs) are implicated in several psych

207 olding protein known to interact with L-type calcium channels (LTCCs), can be specifically coimmunopr

208 at BIN1 interacted with L-type voltage-gated calcium channels (LVGCCs) and that BIN1-LVGCC interactio

209 spontaneous activity, suggesting that T-type calcium channels may represent a pharmacological target

210 Specifically, L-type calcium channel-mediated augmentation of spike-like calc

211 otal firing and the ictal increase of T-type calcium channel-mediated burst firing of thalamocortical

212 ires spontaneous electrical activity and the calcium channel-mediated signaling.

213 stinctions is our identification of P/Q-type calcium channels mediating transmitter release in 1 degr

214 314, this cationic compound inhibited N-type calcium channels more effectively with extracellular tha

215 ygous tottering (tg/tg) mice with a P/Q type calcium channel mutation.

216 R-nicotinic ganglionic alpha-3 receptors and calcium channels (N and P/Q types), but less consistentl

217 la vectensis use a specialized voltage-gated calcium channel (nCa(V)) to distinguish salient sensory

218 at the alpha2delta2 subunit of voltage-gated calcium channels negatively regulates axon growth and re

219 the store-operated calcium release-activated calcium channel of lymphocytes to control transplant rej

220 The calcium channel of sperm (CatSper) is essential for sper

221 te that facilitation can also be impacted by calcium channels opened before spiking begins.

222 d with calpain-1 activation following T-type calcium channel opening, and resulted in the truncation

223 hen fast Synaptotagmin isoforms are far from calcium channels or when specialized sensors, such as Sy

224 e glutamate transporter, and a voltage-gated calcium channel, or if ASP cells lacked Synaptotagmin-4

225 The calcium release-activated calcium channel Orai regulates Ca(2+) entry into non-exc

226 In response to flow, the plasma membrane calcium channel ORAI1 mediates calcium influx in LECs an

227 r the mechanically activated plasma membrane calcium channels Piezo1 and transient receptor potential

228 put train.SIGNIFICANCE STATEMENT CaV1 L-type calcium channels play a key role in regulating the outpu

229 blocking the T-type or L-type voltage-gated calcium channel promoted the spontaneous calcium signali

230 P, an auxiliary subunit of voltage-dependent calcium channels, promoted alpha6beta4 surface expressio

231 In particular, EV-associated annexin calcium channelling proteins, which form a nucleational

232 ptic alpha(2)delta subunits of voltage-gated calcium channels regulate channel abundance and are invo

233 sorders.SIGNIFICANCE STATEMENT Voltage-gated calcium channels regulate important neuronal functions s

234 uences of non-specific sodium permeation via calcium channels remain unknown.

235 a combined effect of sodium, potassium, and calcium channel remodeling and atrial fibrosis.

236 Calcium channels required for symbiosis signaling have b

237 rization and activation of voltage-dependent calcium channels, resulting in calcium influx.

238 us signalling, mediated via NMDAR and L-type calcium channels, results in rapid FOXP1 deSUMOylation.

239 ated hMSC PS effects on cardiomyocyte L-type calcium channel/sarcoendoplasmic reticulum calcium-ATPas

240 n, localizing SNARE proteins proximal to the calcium channel so as to synchronize calcium influx with

241 that disruption of developmentally regulated calcium channel splicing patterns instructively alters d

242 Here we show that the auxiliary calcium channel subunit alpha(2)delta-3 promotes the fun

243 Gene mutations in L-type voltage gated calcium channel subunit genes are strongly implicated as

244 otonin reuptake inhibitors, or alpha-2-delta calcium channel subunit ligands).

245 n subjects as well as aberrant voltage-gated calcium channel subunit protein expression linked to spi

246 ome-wide association study risk genes (e.g., calcium channel subunits [Cacna1c and Cacnb2], cholinerg

247 ism may explain how an altered expression of calcium channel subunits can result in aberrant neuronal

248 aptic AZ molecules that regulate presynaptic calcium channels, synaptic transmission and plasticity i

249 ominent role of low-voltage-activated T-type calcium channels (T-channels) in the firing activity of

250 cumented that the Ca(V)3.3 isoform of T-type calcium channels (T-channels) is inhibited by clinically

251 but neither alone-assemble into a functional calcium channel that is blocked by calmodulin in the res

252 are auxiliary subunits of voltage-dependent calcium channels that also drive synapse formation and m

253 e of TRPV4 channels, which are transmembrane calcium channels that can regulate vascular tone, in mod

254 including glutamate receptors, voltage-gated calcium channels, the dopamine D2 receptor, and compleme

255 powerfully inhibit both sodium channels and calcium channels, thereby blocking both nociceptor excit

256 (2017) show that alpha2delta4 subunits link calcium channels to a trans-synaptic complex with glutam

257 In contrast to VTA, SNc DaNs engage calcium channels to generate action potentials, which le

258 t, the action of Gbetagamma on voltage-gated calcium channels to inhibit calcium influx to the presyn

259 at the calyx synapse in coupling presynaptic calcium channels to release sites.

260 ssays in cells coexpressing transporters and calcium channels to study the effects of increasing N-al

261 2delta binding to gabapentin, and influences calcium channel trafficking and function.

262 own endogenous activator of the ligand-gated calcium channels transient receptor potential V1 and M8

263 receptor, gap junction, and mechanosensitive calcium channel TRPC1 are involved in calcium wave.

264 e, we report that VacA targets the lysosomal calcium channel TRPML1 to disrupt endolysosomal traffick

265 e lipidated LC3 interacts with the lysosomal calcium channel TRPML1, facilitating calcium efflux esse

266 The lysosomal calcium channel TRPML1, whose mutations cause the lysoso

267 d this process is dependent on the lysosomal calcium channel TRPML1.

268 P/protein expression of the mechanosensitive calcium channel, TRPV4.

269 Epithelial calcium channel TRPV6 is a member of the vanilloid subfa

270 We previously proposed that T-type calcium channel (TTCC) expression may serve as a biomark

271 esynaptic Ca(2+) entry via voltage-activated calcium channels (VACCs) is the major trigger of action

272 At chemical synapses, voltage-activated calcium channels (VACCs) mediate Ca(2+) influx to trigge

273 r, by downregulating their voltage-activated calcium channels, vagal motoneurons acquire a stressless

274 INTERPRETATION: Four T-type calcium channel variants and 1 ABCB1 transporter variant

275 receptors (nmdaLTP) or L-type voltage-gated calcium channels (vdccLTP).

276 (2+) levels through the T-type voltage-gated calcium channel (VGCC) and mobilization of Ca(2+) from b

277 ic polymorphisms of the L-type voltage-gated calcium channel (VGCC) are associated with psychiatric d

278 xpression may be common to the voltage-gated calcium channel (VGCC) gene family and may help explain

279 g exon (exon 47) of the Cav2.1 voltage-gated calcium channel (VGCC) gene produces two major isoforms

280 tagamma-mediated modulation of voltage-gated calcium channels (VGCC), inhibition can also be mediated

281 olves purinergic receptors and voltage-gated calcium channels (VGCC).

282 s supported by P/Q- and N-type voltage-gated calcium channels (VGCCs) and negatively regulated by BK

283 For example, presynaptic voltage-gated calcium channels (VGCCs) and postsynaptic ligand-gated i

284 logical manipulation of L-type voltage-gated calcium channels (VGCCs) and purinoceptors induced a two

285 Here, we show that voltage-gated calcium channels (VGCCs) are critical for cellular bindi

286 the molecular organization of voltage-gated calcium channels (VGCCs) within the presynaptic membrane

287 pe glutamate receptors but not voltage-gated calcium channels (VGCCs), and can also be observed in pr

288 rent (I (Ca)) through neuronal voltage-gated calcium channels (VGCCs).

289 ediated, in part, by dendritic voltage-gated calcium channels (VGCCs): pharmacological manipulation o

290 the pore domain of the L-type voltage-gated calcium channel was consistently identified as a biomark

291 This calcium channel was highly expressed in human GBM specim

292 ective for TPCs because knocking down TRPML1 calcium channels was without effect.

293 ore subunit of the calcium release-activated calcium channel, was identified to induce the shear stre

294 ndritic SK channels was occluded when R-type calcium channels were blocked, indicating that the inhib

295 , we show that Ca(2+) influx via STIM1/Orai1 calcium channels, which cluster near FAs, leads to activ

296 e and promote calcium flow through NMDAR and calcium channels, while in turn, calcium activates adeny

297 tch clamp analysis revealed increased L-type calcium channel window current, slow decay time at vario

298 rrent-clamp recordings, inhibition of T-type calcium channels with 1 mum TTA-P2 reduced both the spon

299 eover, the degree of compartmentalization of calcium channels with respect to BK channels and presyna

300 evealed colocalization of D2Rs and Ca(v) 3.2 calcium channels within the axon initial segment.