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1 regulatory role for testicular phosphate and calcium homeostasis.
2 urther insights into the function of WFS1 in calcium homeostasis.
3 The kidney has a major role in extracellular calcium homeostasis.
4 roles in energy production and intracellular calcium homeostasis.
5 hich allow for longitudinal monitoring of ER calcium homeostasis.
6 d as an important regulator of phosphate and calcium homeostasis.
7 ation influx and disruption of intracellular calcium homeostasis.
8 MTC1 and TMTC2 as ER proteins involved in ER calcium homeostasis.
9 identify a new role for AP2 in extracellular calcium homeostasis.
10 als within a cell including dysregulation of calcium homeostasis.
11 optimization of the mechanisms that regulate calcium homeostasis.
12 (NSP4) induces dramatic changes in cellular calcium homeostasis.
13 f AD, including altered lipid metabolism and calcium homeostasis.
14 actin-mediated, and disrupted intracellular calcium homeostasis.
15 ular system protein, is a major regulator of calcium homeostasis.
16 e force-frequency curve, suggesting improved calcium homeostasis.
17 are important in the regulation of cellular calcium homeostasis.
18 l function and survival, i.e., intracellular calcium homeostasis.
19 ell proliferation, cell differentiation, and calcium homeostasis.
20 ered markers of mitochondrial biogenesis and calcium homeostasis.
21 resiliency factor through its modulation of calcium homeostasis.
22 le membrane fragility, but also dysregulated calcium homeostasis.
23 eticulum Ca(2+) ATPase (SERCA) that disrupts calcium homeostasis.
24 COMT, CACNA1C and DRD3 which are related to calcium homeostasis.
25 and has been suggested to have functions in calcium homeostasis.
26 iating calcium spike activity and regulating calcium homeostasis.
27 scular development, endothelial function and calcium homeostasis.
28 cers of energy and play an important role in calcium homeostasis.
29 lism plays in the development of diseases of calcium homeostasis.
30 ation through increased load on dysregulated calcium homeostasis.
31 ochondria cooperate with the SER to maintain calcium homeostasis.
32 , impairs cell cycle progression and affects calcium homeostasis.
33 r barrier function, resulting in the loss of calcium homeostasis.
34 he endoplasmic reticulum and plays a role in calcium homeostasis.
35 eoclasts are essential for bone dynamics and calcium homeostasis.
36 trophy (DMD) include, among others, abnormal calcium homeostasis.
37 a mechanism involving the modulation of the calcium homeostasis.
38 not required for viability, reproduction, or calcium homeostasis.
39 t through the affected channels and disrupts calcium homeostasis.
40 gin and clotrimazole (CLT), which disrupt ER calcium homeostasis.
41 id hormone (PTH), the principal regulator of calcium homeostasis.
42 tein that plays a key role in the control of calcium homeostasis.
43 calcium-selective TRP channel essential for calcium homeostasis.
44 e regulation of apoptosis, cell motility and calcium homeostasis.
45 s, consistent with its role in dysregulating calcium homeostasis.
46 ated protein essential for the regulation of calcium homeostasis.
47 min, a drug known to perturb ER ceramide and calcium homeostasis.
48 response to acute hypoxia and regulation of calcium homeostasis.
49 ultures, SMA astrocytes exhibited defects in calcium homeostasis.
50 o PPT1-deficiency increases ROS and disrupts calcium homeostasis activating caspase-9 and (ii) caspas
51 ts derivatives (Y 134) had a major impact on calcium homeostasis after atRAL exposure in vitro, and w
53 PS is also involved in the regulation of calcium homeostasis, although the precise site of its ac
54 lass B G protein-coupled receptor central to calcium homeostasis and a therapeutic target for osteopo
55 ry (SOCE) is important in the maintenance of calcium homeostasis and alterations in this mechanism ar
57 a link between myocardial isoform switching, calcium homeostasis and altered metabolism in the develo
58 response to mefloquine-induced disruption of calcium homeostasis and appropriate control agents were
59 ic hematopoiesis through maintenance of bone calcium homeostasis and are consistent with the concept
61 clude tissues involved in the maintenance of calcium homeostasis and bone development and remodeling.
64 es MTM1 mutations do not dramatically affect calcium homeostasis and calcium release mediated through
66 ion channels/pumps that alter intracellular calcium homeostasis and cause renin-independent aldoster
67 yzed the sequential steps leading to altered calcium homeostasis and cell death in response to activa
70 l or cell-matrix interaction, Rho signaling, calcium homeostasis and copper-binding/sensitive activit
71 -term OVL did not increase the alteration in calcium homeostasis and did not deplete muscle cell prog
74 ng the mechanisms involved in the control of calcium homeostasis and have provided evidence for a rol
75 saturated fat could lead to abnormalities of calcium homeostasis and heart rhythm by a NOX2 (NADPH ox
77 lso support a role for ICS1 (SA) in iron and calcium homeostasis and identify components of SA cross
80 ption of high-protein diets does not disrupt calcium homeostasis and is not detrimental to skeletal i
81 combined lead to disruption of intracellular calcium homeostasis and isoproterenol-induced arrhythmia
82 ctor, which is shown to play a major role in calcium homeostasis and keratinocyte differentiation.
86 findings link mutations in TRPV4 to altered calcium homeostasis and peripheral neuropathies, implyin
88 oid hormone-related protein (PTHrP) in fetal calcium homeostasis and placental calcium transport was
89 cts of the anti-Abeta antibody aducanumab on calcium homeostasis and plaque clearance in aged Tg2576
92 WFS1 in rat insulinoma (INS1) cells impaired calcium homeostasis and protein kinase B/Akt signaling a
94 her module encloses many genes important for calcium homeostasis and signaling and contains SCA genes
95 hat sigma-1 receptor activation can regulate calcium homeostasis and signaling in RGCs, likely by dir
96 The overrepresentation of genes involved in calcium homeostasis and signaling may indicate an import
98 teraction patterns with proteins involved in calcium homeostasis and sphingolipid metabolism could in
100 These findings establish a role for ERO1 in calcium homeostasis and suggest that modifying the lumen
101 ctively, our findings show that PS regulates calcium homeostasis and synaptic function via RyR and su
102 lications for the long-term monitoring of ER calcium homeostasis and the development of therapeutic a
104 id hormone receptor (PTHR1), which regulates calcium homeostasis and tissue development, has two nati
105 onstrate that modulation of dynamic cellular calcium homeostasis and TXNIP suppression present viable
106 ding neurofilament filled swellings, loss of calcium homeostasis, and accumulation of reactive oxygen
108 se mitochondrial membrane potential controls calcium homeostasis, and AMP-activated protein kinase (A
112 neurotransmitter signaling, perturbations in calcium homeostasis, and damage-associated molecular pat
113 These channels couple lipid metabolism, calcium homeostasis, and electrophysiological properties
114 urite retraction, loss of synapses, aberrant calcium homeostasis, and imbalanced neurotransmitter rel
118 servation of erythrocyte membrane integrity, calcium homeostasis, and osmotic resistance through an a
120 llular functions, such as energy production, calcium homeostasis, and regulating programmed cellular
121 ry results in calcitriol deficiency, altered calcium homeostasis, and secondary hyperparathyroidism,
123 ve been implicated in synaptic transmission, calcium homeostasis, and structural function and thus ma
124 egulation of de novo sphingolipid synthesis, calcium homeostasis, and unfolded protein response.
125 ents), this study suggests that disorders of calcium homeostasis are associated with fatal and nonfat
129 channels TRPV5 and TRPV6 play vital roles in calcium homeostasis as Ca(2+) uptake channels in epithel
130 lays crucial roles in lipid biosynthesis and calcium homeostasis as well as the synthesis and folding
131 rant beta-adrenergic signaling and depressed calcium homeostasis, associated with an imbalance of pro
132 ure 1) the effects of mechanical feedback on calcium homeostasis at the sarcomeric level and 2) the c
134 ting that cerebellar ataxias exhibit altered calcium homeostasis because of metabolic dysregulation,
137 rm black carbon [BC] and PM2.5 levels, serum calcium homeostasis biomarkers (parathyroid hormone, cal
138 tes, mutations in the presenilins also alter calcium homeostasis, but the mechanism linking presenili
139 oupled receptor family C, regulates systemic calcium homeostasis by activating G(q)- and G(i)-linked
140 s (CaR) contribute to regulation of systemic calcium homeostasis by activation of G(q)- and G(i)-link
143 ke many viruses, rotavirus (RV) dysregulates calcium homeostasis by elevating cytosolic calcium ([Ca(
144 is used to examine the regulation of ROS and calcium homeostasis by local, subcellular X-ROS signalin
147 Here we show that modulation of cellular calcium homeostasis can mitigate cytokine- and ER stress
149 The epidermal adrenergic signal controls calcium homeostasis, cell growth, differentiation, motil
150 production, metabolic regulation, apoptosis, calcium homeostasis, cell proliferation, and motility, a
151 Thus, although alterations in intracellular calcium homeostasis contribute to glucocorticoid-induced
152 through modulation of SERCA and maintaining calcium homeostasis could be a therapeutic aim for bette
154 zo1-dependent control of shear flow sensing, calcium homeostasis, cytoskeletal dynamics and pressure-
155 r endothelial cells, TRPV4 channels regulate calcium homeostasis, cytoskeletal signalling and the org
156 ypercalcemia type 3 (FHH3), an extracellular calcium homeostasis disorder affecting the parathyroids,
157 oid plaques in an acute setting and restores calcium homeostasis disrupted in a mouse model of AD upo
158 ty, injuring sarcolemmal membranes, altering calcium homeostasis due to effects on the sarcoplasmic r
159 d the hypothesis that alterations in cardiac calcium homeostasis due to sepsis underlie the observed
160 nflux at afferent ribbon synapses influences calcium homeostasis during long-lasting cholinergic inhi
162 athway commonly linked to HCM progression is calcium homeostasis dysregulation, though how specific m
163 ing low-dose caffeine to mimic the defective calcium homeostasis encountered under these conditions.
164 on, modulation of endoplasmic reticulum (ER) calcium homeostasis, ER stress signaling, autophagy, rea
165 independent function of STING that regulates calcium homeostasis, ER stress, and T cell survival.
168 eal a regulatory role of the PLN pentamer in calcium homeostasis, going beyond the previously hypothe
171 ogenesis, cell proliferation, apoptosis, and calcium homeostasis have been attributed to its N termin
173 s a critical role in cellular energetics and calcium homeostasis; however, how MAM is affected under
175 n up by neurons causing: (i) deregulation of calcium homeostasis, (ii) endoplasmic reticulum-calcium
176 ite degeneration, loss of synapses, aberrant calcium homeostasis, imbalanced neurotransmitter release
177 in vivo, we quantitatively imaged astrocytic calcium homeostasis in a mouse model of Alzheimer's dise
179 te the effect of sigma-1 receptor ligands on calcium homeostasis in a retinal ganglion cell line (RGC
181 turbance in endoplasmic reticulum-associated calcium homeostasis in cultured embryonic motor neurons
182 n D3 (1,25(OH)2D3) plays an integral role in calcium homeostasis in higher organisms through its acti
183 n contractility despite normal intracellular calcium homeostasis in intact cardiomyocytes and resulte
184 levels of ion channels involved in cellular calcium homeostasis in mouse cortical microglial cells i
185 irect damage linked to altered intracellular calcium homeostasis in muscle cells and an indirect toxi
187 nserved role of dematin in the regulation of calcium homeostasis in other cell types will be discusse
188 glutamate receptor signalling and disrupted calcium homeostasis in PNs form a common, early pathophy
189 bellar ataxia type 2 (SCA2) mouse model that calcium homeostasis in PNs is disturbed across a broad r
191 ous system, where it regulates intracellular calcium homeostasis in response to excitatory signaling.
197 elation between IP(3)R elevation and altered calcium homeostasis in terms of either kinetics or dose
199 iquitin-proteasome system and alterations of calcium homeostasis in the neuronal loss observed during
200 gh, and sufficient to maintain intracellular calcium homeostasis in the presence of complete aerobic
201 se may alter glutamate neurotransmission and calcium homeostasis in the retina, which may have implic
202 The hypertension-induced alterations of calcium homeostasis in the soleus muscle of SHRs occurre
203 a simple and sensitive method to monitor ER calcium homeostasis in vitro or in vivo by analyzing cul
204 onstrate that senile plaques impair neuritic calcium homeostasis in vivo and result in the structural
205 harmacological approach to restore cytosolic calcium homeostasis in vivo, we administered the clinica
207 at rs1872328 on ACYP2, which plays a role in calcium homeostasis, increases the risk of ototoxicity b
208 ellular stress signals such as disruption of calcium homeostasis, inhibition of protein glycosylation
209 Cellular stresses such as disruption of calcium homeostasis, inhibition of protein glycosylation
210 t 9-fold from the target organs required for calcium homeostasis (intestine, bone, kidney, and parath
212 suggests that dysregulation of mitochondrial calcium homeostasis is also related to tau and other ris
213 al changes, supports the view that disturbed calcium homeostasis is an early feature of Parkinson's d
214 strongly suggests that imbalance in cellular calcium homeostasis is an important factor leading to CD
222 osphatase (SERCA)2a, a critical regulator of calcium homeostasis, is known to be decreased in heart f
223 uggest that mutant LRRK2 causes a deficit in calcium homeostasis, leading to enhanced mitophagy and d
224 PC1 disease pathogenesis that causes altered calcium homeostasis, leading to the secondary storage of
227 a plethora of cellular processes, including calcium homeostasis, lipid metabolism, membrane biogenes
228 Together, the results indicate that altered calcium homeostasis may be a key early event in basal to
229 and suggest that disruption of intracellular calcium homeostasis may be an early pathogenic event lea
230 Altered glutamatergic neurotransmission and calcium homeostasis may contribute to retinal neural cel
231 ta suggest that BI-1, through its actions on calcium homeostasis, may confer affective resiliency in
232 licated in many neuronal processes including calcium homeostasis, membrane excitability, synaptic tra
233 re interested in the role of channels of the calcium homeostasis modulator (CALHM) family in the huma
241 ently identified large-pore channels are the calcium homeostasis modulators (CALHMs), through which i
245 or TMEM33 in the regulation of intracellular calcium homeostasis of renal proximal convoluted tubule
246 show that blocking this channel perturbs the calcium homeostasis of the cells and inhibits the prolif
249 se observations suggest an important role of calcium homeostasis on the Apaf-1-dependent apoptotic pa
250 dentified have functions related to neuronal calcium homeostasis or central nervous system developmen
251 nd this effect was not due to alterations in calcium homeostasis or myosin light chain phosphorylatio
252 D3 [1,25(OH)2D3] to perform its function in calcium homeostasis, or it is activated by lithocholic a
255 alcium is an abundant intracellular ion, and calcium homeostasis plays crucial roles in several cellu
257 rticoid-induced alterations in intracellular calcium homeostasis promote apoptosis, but the mechanism
258 ive oxygen species production and signaling, calcium homeostasis, regulated cell death, and heme bios
259 in-coupled receptor important for regulating calcium homeostasis, regulates neurite growth in two dis
261 tabolic derangements (particularly involving calcium homeostasis), renal failure, and possibly, morta
262 phenotypes, such as alkaline pH sensitivity, calcium homeostasis, respiratory defects, and cell wall
263 naptic cistern may play an essential role in calcium homeostasis, serving as sink or source, dependin
265 tions at the level of glial gene expression, calcium homeostasis, swelling, and volume regulation.
266 min D is a secosteroid with known effects on calcium homeostasis that has recently been shown to have
267 that the mutant iPSC-CMs displayed aberrant calcium homeostasis that led to arrhythmias at the singl
268 oncentrations induce a stochastic failure of calcium homeostasis that precedes both mitochondrial dep
269 nes are known to play a contributory role in calcium homeostasis, the entire caste of key components
270 itially thought to play a restricted role in calcium homeostasis, the pleiotropic actions of vitamin
271 aused a phenotype-dependent dysregulation of calcium homeostasis; the resting intracellular calcium o
273 well as core biological processes mediating calcium homeostasis, tissue integrity, cornification, an
274 fficking of ion channel subunits involved in calcium homeostasis to and from the plasma membrane.
276 er se, is the key effector of Drp1, altering calcium homeostasis to modulate neuronal morphology and
277 improving endoplasmic reticulum-mitochondria calcium homeostasis to prevent excess calcium overload a
278 data link defects in neuronal intracellular calcium homeostasis to the vulnerability of central auto
279 ecies, electron transport chain function and calcium homeostasis trigger altered mitochondrial dynami
281 over 6 days was confirmed by assessing their calcium homeostasis, twitch force generation, and respon
282 to explore the ability of BI-1 to influence calcium homeostasis under basal conditions and also foll
283 These results suggest that disruption of calcium homeostasis underlies isoflurane-induced caspase
284 by which PS regulates synaptic function and calcium homeostasis using acute hippocampal slices from
285 ion due to its ability to stabilize cellular calcium homeostasis via N-methyl-D-aspartate-receptor an
286 upts mitochondrial and endoplasmic reticulum calcium homeostasis via ryanodine receptor (RyR) activat
287 etabolite, NAADP(+), regulates intracellular calcium homeostasis via the 2-pore channel, ryanodine re
289 gland VDR content is an important factor in calcium homeostasis, vitamin D metabolism, and the treat
291 valuate the effects of early intervention in calcium homeostasis, we used 2 mouse models of sarcomeri
292 ne permeability and consequent disruption of calcium homeostasis were implicated in cellular degenera
293 ochondrial morphology modulation on cellular calcium homeostasis were measured in intact cells; mitoc
295 heimer's disease (AD), disturb intracellular calcium homeostasis, which in turn activates the calcium
296 utophagic/lysosomal system and intracellular calcium homeostasis, which underlie vulnerability to neu
298 vement of endoplasmic reticulum-mitochondria calcium homeostasis with hepatic HAX-1 inactivation sugg
299 hat PTHrP is an important regulator of fetal calcium homeostasis with its predominant effect being on