ライフサイエンスコーパス: calcium ion

1 subtle porin-LPS interactions and a bridging calcium ion.

2 vicinal diol coordinates to a protein-bound calcium ion.

3 zyme increased in the presence of starch and calcium ion.

4 irmed that modified hPC2 binds an additional calcium ion.

5 ia a transition state capable of binding one calcium ion.

6 production, respectively, in the presence of calcium ion.

7 N-terminal IgV domain in coordination with a calcium ion.

8 -sensing receptor, which binds at least five calcium ions.

9 calcium ions, providing a linear response to calcium ions.

10 anoparticles with pectic polysaccharides and calcium ions.

11 rs of LPS molecules, which are stabilized by calcium ions.

12 ociation and dissociation in the presence of calcium ions.

13 S100 domain of human profilaggrin with bound calcium ions.

14 tidylcholine (DMPC) bilayer coincubated with calcium ions.

15 transmit important information by conducting calcium ions.

16 abilized by disulfide bonds and chelation of calcium ions.

17 lays a jellyroll beta-sandwich including two calcium ions.

18 anoparticles with variable concentrations of calcium ions.

19 ch sodium is the most likely substituent for calcium ions.

20 and the oxidation of thiol groups induced by calcium ions.

21 n the same time scale as the dissociation of calcium ions.

22 ing to Galpha subunits and its regulation by calcium ions.

23 itivity of dopamine release to extracellular calcium ions.

24 nding to Sonic hedgehog (Shh) is enhanced by calcium ions.

25 dic device, thus reducing the pH and freeing calcium ions.

26 iols depending on the absence or presence of calcium ions.

27 uced phosphate precipitation with coexisting calcium ions.

28 site of protein folding and a reservoir for calcium ions.

29 thways, relying on second messengers such as calcium ions.

30 s solid hydrogel matrices by adding divalent calcium ions.

31 ication, HG can form complexes with divalent calcium ions.

32 as defined by CD is the same with or without calcium ions.

33 oyment of genetically encoded indicators for calcium ions (a proxy for action potentials), membrane p

34 r other electrolytes (potassium, sodium, and calcium ions), a PVC-based ion-selective membrane is add

35 x with hydroxycarboylate groups affected the calcium ion activity, which may influence the gelation p

36 rations in the dispersed phase increased and calcium-ion activity (ACa(++)) decreased during manufact

37 ed the effects of calcium chelating salts on calcium-ion activity (ACa(++)), calcium distribution, an

38 The calcium ion acts as a second messenger in response to me

39 ch studied in an underivatized form as their calcium ion adducts, barium ion adducts, and gas-phase e

40 in hemolymph sodium ions and an increase in calcium ions after 24 h post-exposure.

41 Calcium ions also facilitated HSA adsorption likely thro

42 ike (cbEGF) domains, each of which binds one calcium ion and is stabilized by three highly conserved

43 nct structural rearrangements in response to calcium ion and small molecule inhibitors such as triflu

44 DAR), which leads to influx of extracellular calcium ions and activation of calcium-dependent phospha

45 C-terminal tail of alpha-syn is regulated by calcium ions and floats in solution in two conformations

46 ccharide contents, our results indicate that calcium ions and HG gelation increase the amount of boun

47 A strict dependence for calcium ions and inhibition at high NaCl concentration w

48 lf-association was measured as a function of calcium ions and loading rate.

49 have high cation photocurrent but pass fewer calcium ions and protons.

50 rypsin can be stabilized by a combination of calcium ions and sodium chloride, which enables protein

51 any organism; this activity was inhibited by calcium ions and stimulated by bicarbonate.

52 Compared to a control, presence of calcium ions and tannic acid decreased FL formation sign

53 Removal of calcium ions and the consequent extraction of homogalact

54 state transitions and its interactions with calcium ions and the three binding partners mentioned ab

55 ase of phosphate depends on concentration of calcium ions and this influences soluble oxalate concent

56 permeate divalent cations, are inhibited by calcium ions, and demonstrate weak rectification in asym

57 aI: unbound enzyme, a DNA-bound complex with calcium ions; and a DNA-bound, fully cleaved complex wit

58 The H(+)/Ca(2+) (calcium ion) antiporter (CAX) plays an important role in

59 Addition of calcium ions appeared to result in release of the second

60 ), negatively charged membrane vesicles, and calcium ions approached the same diffusion-limited rate

61 brane shows no response in the ON state when calcium ions are absent.

62 nt with experimental data and confirmed that calcium ions are bridged between polymer chains, resulti

63 to a network of vacuoles and vesicles, where calcium ions are concentrated until they precipitate in

64 Calcium ions are crucial for the antibacterial activity

65 Calcium ions are essential to signal transduction in vir

66 Because calcium ions are important biological cofactors that pla

67 Calcium ions are involved in a plethora of cellular func

68 s among charged residues, lipid bilayer, and calcium ions are optimized to provide additional attract

69 Calcium ions are well-known intracellular signalling mol

70 ered at the base of the spine by the fastest calcium ions arriving at a Ryanodyne receptor (RyR).

71 Finally, we demonstrate the influx of calcium ions as a response of our mechanically activated

72 d on lipid monolayers in the absence of free calcium ions as revealed by electron microscopy.

73 and real-time monitoring of fluctuations of calcium ions associated with focal ischemia using a mole

74 he continuous matrix was firstly attacked by calcium ions at low lime levels (<0.20% w/w), disrupting

75 e, and anti-glycation agents (tannic acid or calcium ion) at different molar ratios were heated at 90

76 Calcium ions bind preferentially at an external site, at

77 Calcium ions bind specifically in the Tse3 active site a

78 Calcium ions bind to lipid membranes containing anionic

79 aptic transmission (P = 2.70 x 10(-)(1)(4)), calcium ion binding (P = 3.55 x 10(-)(1)(5)), and cation

80 perties have been studied in detail, but its calcium ion binding properties and subsequent conformati

81 F3 constitute a rigid rod via an interdomain calcium ion binding site, the long linker between EGF1 a

82 f three to six corresponding to the multiple calcium ion binding sites on the calcium sensor responsi

83 Calcium ion binding to CaM induced an increase in thickn

84 Human calmodulin mutations disrupt calcium ion binding to the protein and are associated wi

85 transmembrane transporter activity, iron and calcium ion binding, (inorganic) anion transmembrane tra

86 Many have proposed that calcium ions binding to daptomycin is a precondition for

87 e CUB module from human TSG-6, identifying a calcium ion-binding site and chelating glutamic acid res

88 tion may also provide an explanation for how calcium-ion-binding affinity is increased upon binding a

89 100B would also have to cause an increase in calcium-ion-binding affinity to be effective therapeutic

90 Interestingly, this enzyme contains a calcium ion bound nearby to the glycone-binding region,

91 Calcium ions bound both strongly and weakly to fibrin(og

92 of CaM for CaMKII depending on the number of calcium ions bound to the former.

93 is crucial because of high energy needs and calcium ion buffering along axons to synapses during neu

94 e phi6, the assembly reaction is promoted by calcium ions but its biomechanics remain poorly understo

95 Chelation of calcium ions by 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-

96 ey events underlying the active transport of calcium ions by SERCA.

97 etry was used to characterize the binding of calcium ion (Ca(2)(+)) and phospholipid to the periphera

98 eptor (ITPR3) is the principal intracellular calcium ion (Ca(2+) ) release channel in cholangiocytes,

99 ound to form networks exhibiting synchronous calcium ion (Ca(2+)) activity that stimulated cell proli

100 nce the activity of ryanodine receptor (RyR) calcium ion (Ca(2+)) channels, which play a central role

101 sed to the extracellular space due to a high calcium ion (Ca(2+)) concentration and finally reached t

102 Intracellular calcium ion (Ca(2+)) elevation on the left side of the m

103 monary vasculature leads to perturbations in calcium ion (Ca(2+)) homeostasis and transition of pulmo

104 ar-infrared fluorescent, genetically encoded calcium ion (Ca(2+)) indicator (GECI) with excitation an

105 The introduction of calcium ion (Ca(2+)) indicators based on red fluorescent

106 om one color to another by illumination, and calcium ion (Ca(2+)) indicators.

107 Calcium ion (Ca(2+)) is a versatile second messenger tha

108 ing materials are clinically being used, and calcium ion (Ca(2+)) released from these materials is kn

109 oped FP-calmodulin biosensor, GEM-GECO1, for calcium ion (Ca(2+)) sensing.

110 In neurons, PDZD8 was required for calcium ion (Ca(2+)) uptake by mitochondria after synapt

111 ther these channels signal via the influx of calcium ion (Ca(2+)), voltage-dependent conformational c

112 The C2A domain is one of two calcium ion (Ca(2+))- and membrane-binding domains withi

113 vity in the developing brain, is mediated by calcium ion (Ca(2+))-dependent activation of Ca(2+)/calm

114 r potential melastatin member 8 (TRPM8) is a calcium ion (Ca(2+))-permeable cation channel that serve

115 lling are nuclear-associated oscillations in calcium ions (Ca(2+) ), occurring in the root hairs of s

116 Rapid influx of calcium ions (Ca(2+)) across the plasma membrane has an

117 ive oxygen species (ROS) that, together with calcium ions (Ca(2+)) and pH, sustain polar growth over

118 Calcium ions (Ca(2+)) are critical second messengers in

119 Calcium ions (Ca(2+)) are essential for many cellular si

120 viruses use specific viral proteins to bind calcium ions (Ca(2+)) for stability or to modify host ce

121 Calcium ions (Ca(2+)) function as universal second messe

122 5 (mGluR5)-dependent increases in cytosolic calcium ions (Ca(2+)) in response to glutamatergic trans

123 Intracellular calcium ions (Ca(2+)) modulate sodium channel inactivati

124 Calcium ions (Ca(2+)) modulate the phototransduction cas

125 selectivity filter is partially selective to calcium ions (Ca(2+)) moving into the cell, but blocked

126 me coronavirus (SARS-CoV) FP have shown that calcium ions (Ca(2+)) play an important role in fusogeni

127 lly coupled ferric iron ions (Fe(3+)), three calcium ions (Ca(2+)), and an oxo group bridging three o

128 o membranes containing PS in the presence of calcium ions (Ca(2+)), but whose function is unknown.

129 mbranes, both in the absence and presence of calcium ions (Ca(2+)), is critical to its central role i

130 Calcium ions (Ca(2+)), ubiquitous signaling and second m

131 us considered here is on K(+) efflux through calcium-ion (Ca(2+))-activated Gardos channels.

132 ations of the intracellular concentration of calcium ion ([Ca(2+)](i)) are at the heart of intracellu

133 In hippocampal neurons, calcium ion (Ca2+) flux through N-methyl-D-aspartate (NM

134 Near-infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs) can provide advant

135 Signal transduction via calcium ions (Ca2+) represents a fundamental signaling p

136 ease cheese yield but high concentrations of calcium ions can have adverse effects.

137 Voltage-gated calcium ion (CaV) channels convert neuronal activity int

138 First, calcium ions change the tertiary structure of the bound

139 ies of steps that involve a sudden influx of calcium ions, changes in mitochondria, and modification

140 enriched gene sets include the voltage-gated calcium ion channel and the signalling complex formed by

141 A native calcium ion channel has been identified in bacteria for

142 th Ca(2+), further indicating that CD20 is a calcium ion channel that can transport these metal ions

143 aker gene programs (neuronal, Wnt signaling, calcium/ion channel activity).

144 The overall properties of presynaptic calcium ion channels appeared normal, as reflected by th

145 Membrane current through voltage-sensitive calcium ion channels at the postsynaptic density of a de

146 e hypothesize that activation of light-gated calcium ion channels by blue and green light could expla

147 Calcium ion channels that determine many of the properti

148 Polycystins function as calcium ion channels, but their impact on cell physiolog

149 his F-actin peripheralization was blocked by calcium ion chelation.

150 cium ion rich fluids, the strong carboxylate-calcium ion complexes prevented direct carboxylate-calci

151 sient increase in endothelial cytosolic free calcium ion concentration ( upward arrow[Ca(2+)]i) is re

152 gen substrate topography, free intracellular calcium ion concentration ([Ca(2+)]i, and the associatio

153 SAM causes transient changes in cytoplasmic calcium ion concentration (Ca(2+)) and that transient Ca

154 showed that an increase of the intracellular calcium ion concentration [Ca(2+) ] causes a rapid and t

155 ions (pH 4.5), BAG was found to increase the calcium ion concentration from 0.7 mM ([Ca(2+)] in artif

156 e dependence of important cellular events on calcium ion concentration propelled us to investigate th

157 R stress in SMCs was increased intracellular calcium ion concentration, resulting in increased contra

158 pecially by reports of altered intracellular calcium ion concentrations ([Ca(2+)]).

159 e Ras-ERK pathway and increase intracellular calcium ion concentrations, whereas PLC-gamma1 is dispen

160 physiological temperatures and low divalent calcium ion concentrations.

161 readily adjusted by varying the ethanol and calcium ion contents from 0 to 50% v/v and from 0 to 2 m

162 lesions opens to allow influx of sodium and calcium ions, contributes to axonal injury in experiment

163 s were about two to three fold higher in the calcium ion deficient fluids compared to the calcium ion

164 Moreover, in calcium ion deficient fluids, the adhesion forces were s

165 Third, because calcium ions demonstrate strong affinity to negatively c

166 ntitative analysis of potassium, sodium, and calcium ions, demonstrated here in highly colored fruit

167 Moreover, we explore the differential calcium ion dependence of calmodulin ligand-binding affi

168 entation of ALS relevant pathways, including calcium ion dependent exocytosis, synaptic transport and

169 The antibiotic activity is calcium-ion dependent and correlates with the target mem

170 Three-dimensional pH and calcium ion distribution mapping were also obtained by u

171 ton, suggesting that influx of extracellular calcium ions drives spine shrinkage.

172 The calcium ions electrostatically stabilize the lone pair o

173 gamma1 activation and subsequent cytoplasmic calcium ion elevation.

174 k blood flow due to a deficiency in a sodium calcium ion exchanger expressed specifically in the hear

175 We conclude that in each cell the calcium ions exist in a continuum of states.

176 stronger on the calcite surfaces with higher calcium ion exposures.

177 with the fluorescent dye calcein shows that calcium ions first penetrate the embryo and later are de

178 izing optical calcium imaging, which records calcium ion flux indicating occurrence of an action pote

179 els and contributes to the driving force for calcium ion flux that triggers neurotransmission at pres

180 Results indicated that PLA2 required calcium ion for both the hydrolyzing activity and the an

181 Highly reactive calcium ions form a direct interaction with starch to al

182 that take place subsequent to removal of the calcium ion from the regulatory sites I and II.

183 new study reveals a role for the release of calcium ions from intracellular stores in mediating spat

184 ed inhibition of thrombin-induced release of calcium ions from intracellular stores.

185 ykinin triggers the release of intracellular calcium ions from nociceptive sensory neurons of rat dor

186 SERCA promotes muscle relaxation by pumping calcium ions from the cytoplasm into the sarcoplasmic re

187 y, we observed force-induced dissociation of calcium ions from the duplicated loop-helix F-hand motif

188 echanics of the capsid: the sequestration of calcium ions from the intracapsid binding sites reduces

189 e major cellular mediators of the release of calcium ions from the sarcoplasmic reticulum, an essenti

190 the notion that CP responds to physiological calcium ion gradients to become a high-affinity transiti

191 The role of the cofactor, calcium ions, has been confusing.

192 m, phospholipid biosynthesis/metabolism, and calcium ion homeostasis.

193 tends out into the solvent and away from the calcium ion; however, in the complexes, the Glu-202 side

194 mbbell EF-hand protein that accommodates one calcium ion in its fourth EF-hand.

195 To remove noise, we prepare a pair of calcium ions in a superposition of two decoherence-free

196 iveness of BAG in neutralizing and releasing calcium ions in acidic conditions.

197 , permease activity required the presence of calcium ions in both the association and activation step

198 nation shell, we determined the state of the calcium ions in each particle.

199 or the transient elevation of cytosolic-free calcium ions in endothelium that is required for TEM and

200 hows an absolute requirement of magnesium or calcium ions in enzyme activity.

201 l gel electrophoresis, the identification of calcium ions in protein spots by X-ray fluorescence (SR-

202 formation pathway of calcium carbonate from calcium ions in sea water to mineral deposition and inte

203 ations of negatively charged amino acids and calcium ions in the Abeta binding footprint overlap.

204 zed by hydroxyl ligands and charge balancing calcium ions in the interlayer space.

205 Presence of calcium ions in the intestinal fluid decreased the free

206 ggered by an elevated total concentration of calcium ions in the mitochondrial matrix, leading to dis

207 This work shows the mechanical role of calcium ions in viral shell stability and identifies TBS

208 f excess intracellular cations, particularly calcium ions, in neuronal and glial cell injury in multi

209 Calcium ion influx through NMDARs recruits Ca(2+)-depend

210 tential target for Parkinson's disease since calcium ion influx through the channel was implicated in

211 sights for the competing carboxylate/calcite/calcium ion interactions.

212 split an electron wave packet bound inside a calcium ion into two parts with different orientations a

213 o form the channel that controls the flow of calcium ions into mitochondria.

214 self-healing protein gel is made by inducing calcium ions into the mixture of heat-induced BSA nano-a

215 cle is regulated by the influx and efflux of calcium ions into the muscle cytoplasm.

216 they regulate the conductance of sodium and calcium ions, intravesicular pH, trafficking and excitab

217 Calcium ion is a versatile second messenger for diverse

218 Calcium ion is an intracellular messenger that plays a c

219 TnC domain in which the presence of only one calcium ion is sufficient to induce a closed-to-open tra

220 ly, the simultaneous detection of sodium and calcium ions is enabled voltammetrically in contrast to

221 cium ions, with a population of inner-sphere calcium ions larger than on unconfined calcite surfaces.

222 The visinin-like domain binds three calcium ions, leading to a conformational change involvi

223 embranes of mitochondria can be triggered by calcium ions, leading to swelling of the organelle, disr

224 Opening can be triggered by calcium ions, leading to swelling of the organelle, disr

225 y be disrupted in diseases where cytoplasmic calcium ion levels are chronically high and where target

226 (K(d) </= 20 nM) implied occupancy at basal calcium ion levels.

227 This mechanism involves two factors: 1) calcium ions make the DMPC bilayer partially cationic an

228 Our experiments show that calcium ions modulate the mechanics of the capsid: the s

229 ly of factor Xa, factor Va, prothrombin, and calcium ions, myosin greatly enhanced prothrombinase act

230 By contrast, the voltammetric exchange of calcium ion (nI = 3) with lithium ion (nJ = 1) by a Ca(2

231 ese simulations, we have determined that the calcium ions not only stabilize the cis peptide bond the

232 rmed by Asp116 and Arg92 in the place of the calcium ion of the dormant (high-calcium) state might tr

233 The affinity for calcium ions of visinin-like domain EF-hands 1 and 2 (K(

234 e deleterious effects of abrupt increases in calcium ion on membrane potential during reperfusion.

235 Effects of enzyme dose, pH, and calcium ion on the ability of PLA2 to inhibit trout hemo

236 ly through carboxylate interactions with the calcium ions on calcite surfaces.

237 ermal stability upon association with either calcium ions or crystalline HAP.

238 der coordination shell, the newly identified calcium ion organizes the active site residues to mediat

239 tability are dependent on the binding of one calcium ion per protein molecule.

240 of the P-type ATPases family, transports two calcium ions per hydrolyzed ATP molecule via an "alterna

241 Herein, we have revealed that magnesium and calcium ions play a major role in modulating the ability

242 Regardless of calcium ion presence, the fluorescence intensity results

243 Mitochondrial calcium ions promote a number of events that sustain ATP

244 r knowledge, physiological mechanism whereby calcium ions promote sodium current facilitation due to

245 +)-binding moiety, has two binding sites for calcium ions, providing a linear response to calcium ion

246 Calcium ions react with silicic acid released from disso

247 ABSTRACT: Calcium ions regulate mitochondrial ATP production and c

248 KEY POINTS: Calcium ions regulate mitochondrial ATP production and c

249 r fish cardiovascular health through altered calcium ion regulation.

250 The present study investigated whether calcium ion release (CIR) affects their biological and a

251 lex diterpenoids that modulate intracellular calcium-ion release at ryanodine receptors, ion channels

252 The calcium ion remains bound to wild-type OLF at neutral an

253 calcium ion deficient fluids compared to the calcium ion rich fluids for all calcite surfaces.

254 n results unambiguously demonstrated that in calcium ion rich fluids, the strong carboxylate-calcium

255 AFM tips showed mitigated adhesion forces in calcium ion rich fluids.

256 ial protocol is established on potassium and calcium ion-selective membranes.

257 tate, low-poly(vinyl chloride), carbon-based calcium ion-selective microelectrode (Ca(2+)-ISME), 25 m

258 BtuB, and earlier simulations suggested that calcium ions serve to stabilize key substrate-binding ex

259 Calcium ion signaling regulates central aspects of the b

260 tein (WASP) deficiency results in defects in calcium ion signaling, cytoskeletal regulation, gene tra

261 erstanding of the events connecting WASP and calcium ion signaling.

262 gron substrates, modulates G protein-coupled calcium ion signals and mitogen-activated protein kinase

263 A calcium ion, sodium ion and glycerol molecule were ident

264 At higher concentrations, calcium ions stabilize monomeric RsaA, which can then tr

265 Calcium ion stimulated the production of 2-arachidonoyl-

266 y activated TMEM16A, leading to depletion of calcium ion stores and store-operated calcium influx.

267 on our data, we propose a mechanism by which calcium ions strengthen Abeta-bilayer interactions.

268 ocation is also regulated by nucleotides and calcium ions, suggesting a potential role of the transpo

269 cin M reveals the presence of an active site calcium ion that is coordinated by a conserved aspartic

270 r release is triggered by the binding of few calcium ions that can originate either from the synaptic

271 s peak absorbance at 765 nm upon addition of calcium ions that was translated into robust signal chan

272 Moreover, with the presence of calcium ions, the self-healing behavior can be significa

273 potentials and are modulated by cytoplasmic calcium ions through a poorly understood mechanism.

274 Abeta monomer does not promote permeation of calcium ions through the zwitterionic bilayer.

275 Herein, we used the biologically relevant calcium ion to investigate the conformation of monomeric

276 With high initial ratio of calcium ion to phosphate, periodic precipitation was obt

277 creases from 21.4 kcal/mol in the absence of calcium ions to 10.3 kcal/mol in their presence.

278 O biofouling was enhanced by complexation of calcium ions to bacterial EPS.

279 a cascade of pathological events by allowing calcium ions to enter the cell.

280 n methylesterase enzymes and cross-linked by calcium ions to form a gel.

281 ulphonate (PSS), we show that the binding of calcium ions to form Ca-PSS globules is a key step in th

282 artilage via the generation of intracellular calcium ion transients.

283 ators emerge from i) mechanical stretch with calcium ion transport and ii) fluid shear stress induced

284 L to play a regulatory role in mitochondrial calcium ion transport.

285 ium histolyticum collagenase, the binding of calcium ions triggers the formation of a cis peptide bon

286 required for chloride ion efflux induced by calcium ion uptake, and demonstrate that fibre formation

287 revealed how some GH43 ABNs are activated by calcium ions via hyperpolarization of the catalytically

288 ging, where bacterial EPS in the presence of calcium ions was globular, while that with magnesium ion

289 olayer of cultured cells, which fluoresces a calcium ion wave at a controlled ionic current.

290 e is shown to actively exchange protons with calcium ions when switched ON after illumination at 470

291 Moreover, we demonstrate that calcium ions, which bind within the confines of the TolB

292 oacid polymer in an ion-sensing membrane for calcium ions, which highly discriminates potassium, sodi

293 tions controlling the release and effects of calcium ions, which may regulate migration in a spaciote

294 is used as a stimulus to liberate liposomal calcium ions, which then trigger the enzymatic activity

295 ts reversible interaction with extracellular calcium ions, while applying a remote transient middle c

296 activity, whereas removal of the more buried calcium ion with EDTA resulted in a 60-90% reduction in

297 Myoferlin C2A, on the other hand, binds two calcium ions with an affinity 3-fold lower than that of

298 ons that utilize an accurate force field for calcium ions with scaled charges effectively accounting

299 H probe was used to correlate the release of calcium ions with the change in local pH.

300 se counterions to be inner- and outer-sphere calcium ions, with a population of inner-sphere calcium