ライフサイエンスコーパス: calcium-binding

1 at perforin becomes membranolytic only after calcium binding.

2 ile maintaining conservation in N-acetyl and calcium binding.

3 sly unknown determinant of CaV high-affinity calcium binding.

4 ellular protein SMOC2 (SPARC related modular calcium binding 2) presenting severe oligodontia, microd

5 The calcium-binding 2EF-hand protein Phl p 7 from timothy gr

6 MPCs displayed increased expression of S100 calcium-binding A4 (S100A4), a protein linked to cancer

7 Nerve injury increased ionized calcium binding adapter molecule 1 (Iba1) and phosphoryl

8 et of rapamycin signaling, levels of ionized calcium-binding adapter molecule 1 and glial fibrillary

9 The panmicroglial marker ionized calcium-binding adapter molecule 1 was decreased in all

10 lary acidic protein) and microglial (ionized calcium-binding adapter molecule 1) markers was performe

11 stic groups did not differ regarding ionized calcium-binding adapter molecule 1+ immunoreactivity for

12 d increased lymphocyte expression of ionized calcium-binding adapter molecule 1, toll-like receptor 2

13 nohistochemical staining showed more ionized calcium-binding adapter molecule 1-positive cells in the

14 ma, tumor necrosis factor alpha, and ionized calcium binding adaptor molecule 1 (Iba1) expression lev

15 ysts were located within accumulated ionized calcium binding adaptor molecule 1 (Iba1)-positive micro

16 ctivation transcription factor 3 and ionized calcium binding adaptor molecule 1 for neurons and glia,

17 d the presence of CD68(+), F4/80(+), ionized calcium binding adaptor molecule 1(-) macrophages contai

18 fibrillary acidic protein (GFAP) and ionized calcium binding adaptor molecule 1(IBA1) immunostaining

19 ary acidic protein), and microglial (ionized calcium binding adaptor molecule 1) markers was performe

20 es of amyloid-beta (4G8), microglia (ionized calcium binding adaptor molecule 1), astrocytes (glial f

21 ), microglial/macrophage activation (Ionized calcium binding adaptor molecule-1 [Iba-1]) and interleu

22 constitutive astrocytic markers, and ionized calcium-binding adaptor molecule 1 (IBA1) as a constitut

23 neuroinflammatory markers including ionized calcium-binding adaptor molecule 1 (Iba1), glial fibrill

24 Furthermore, ionized calcium-binding adaptor molecule 1 staining revealed red

25 ociated with significantly increased ionized calcium-binding adaptor molecule 1-positive microglial a

26 We ask whether domain interactions and calcium binding affect Protein S folding and potential s

27 calcium oscillations that uses differential calcium binding affinities to create a robust molecular

28 The interaction does not directly affect the calcium binding affinity of cNTnC.

29 odulins exhibited several-fold reductions in calcium binding affinity.

30 90T in hippocalcin did not affect stability, calcium-binding affinity or translocation to cellular me

31 activity of patients' IgE and mAb102.1F10 to calcium-binding allergens and peptides thereof were stud

32 Calcium binding allosterically activates the enzyme, but

33 3-3 protein-mediated activation of Nth1, and calcium binding, although not required for the activatio

34 On calcium binding, an amphipathic helix of the C-terminal

35 Calcium binding and dissociation within the cardiac thin

36 TMEM16A is opened by voltage-dependent calcium binding and regulated by permeant anions and int

37 bes of calmodulin show subtle differences in calcium binding and target recognition; these are import

38 hat the folding of BapA BIg domains requires calcium binding and the folded domains have differential

39 clinical variations are shown to impair its calcium-binding and calcium-dependent structural changes

40 two consensus motifs overlapping the site of calcium-binding and dimerization of the cadherin molecul

41 onents with osteoblast-derived MVs including calcium-binding and extracellular matrix proteins.

42 Annexin A5 belongs to a large family of calcium-binding and phospholipid-binding proteins and ma

43 ese studies reveal central roles for ATP and calcium binding as regulators of calreticulin-substrate

44 An essential calcium-binding aspartate residue, Asp307Ala, was disrup

45 fusion studies with intact MUC5B showed that calcium binding at the protein site catalyzed reversible

46 ochemical and physiological basis for RsaA's calcium-binding behavior, which extends far beyond calci

47 ility and conformational dynamics of a model calcium-binding betagamma-crystallin protein, Protein S,

48 The multidomain calcium-binding betagamma-crystallin proteins are partic

49 assessed the effects of these alterations on calcium binding by calmodulin and on binding and activat

50 High-affinity calcium binding by calreticulin is required for optimal

51 P2 levels, which are generated downstream of calcium binding by neuronal calcium sensors such as hipp

52 Indeed, calcium binding by recoverin results in the extrusion of

53 f major UNC-13/Munc13 isoforms contain a non-calcium binding C2A domain that mediates protein homo- o

54 nantly colocalized in particles, whereas the calcium-binding calcein label is mainly excluded from th

55 olin second domain, without compromising its calcium binding capacity.

56 strate that lipid membranes have substantial calcium-binding capacity, with several types of binding

57 Perturbed calcium binding caused by cbEGF domain mutations is thus

58 ps13 and its surprising binding partner, the calcium-binding centrin Cdc31, in trans-Golgi network (T

59 Calreticulin is a calcium-binding chaperone that has several functions in

60 Calreticulin is a calcium-binding chaperone that is normally localized in

61 raphic structure of LipL32 revealed that the calcium-binding cluster of LipL32 includes several essen

62 In conclusion, the calcium-binding cluster of LipL32 plays essential roles

63 ulin, an endoplasmic reticulum (ER) luminal, calcium-binding component of the PLC that is known to bi

64 imulations, we demonstrate that cbEGF domain calcium binding decreases under mechanical stress (i.e.

65 of Munc13-4 and Rab11, while expression of a calcium binding-deficient mutant of Munc13-4 significant

66 lin mutants that affect ATP or high-affinity calcium binding display prolonged associations with mono

67 level enrichment analysis identified EF-hand calcium binding domain 14 as a novel susceptibility gene

68 ; however, the specific function of the S100 calcium-binding domain in profilaggrin biology is poorly

69 d heterozygous missense mutations in the C2B calcium-binding domain of the gene encoding Synaptotagmi

70 Here, we identify EF-hand calcium-binding domain-containing protein 9 (EFCAB9) as

71 per 3D configuration of Nth1's catalytic and calcium-binding domains relative to each other, thus sta

72 g common collagen-binding domains and unique calcium-binding domains, were synthesized by solid-phase

73 reduce levels of proteins within the soluble calcium-binding double C2 domain (Doc2)-like protein fam

74 Finally, by using a calcium-binding dye as an indicator, we demonstrate in-d

75 ons markedly disrupt normal mechanosensitive calcium binding dynamics.

76 ound that SMOC-EC, lacking the extracellular calcium binding (EC) domain, inhibited BMP2 signaling, w

77 ith a semisequential pathway that favors the calcium binding EF-hands of the C-terminal lobe over tho

78 e functionally active if the second (native) calcium-binding EF hand is intact.

79 Within the PC2 Cterm, there is a calcium-binding EF-hand domain, crucial for the calcium-

80 In our study, we discovered a characteristic calcium-binding EF-hand-like motif in NS2 and found that

81 domain adjacent to the kinase domain and two calcium-binding EF-hands at its N terminus.

82 N-terminal regulatory domain containing four calcium-binding EF-hands, a linker loop domain with an a

83 aracterize a rhomboid protease that harbours calcium-binding EF-hands.

84 DAMTS3) and the secreted factor collagen and calcium binding EGF domains 1 (CCBE1) in this process.

85 tivation, which was enhanced by collagen and calcium binding EGF domains 1 (CCBE1).

86 Collagen- and calcium-binding EGF domain-containing protein 1 (CCBE1)

87 ing N-terminus, extended central array of 11 calcium-binding EGF domains and flexible TGFbeta-binding

88 and compound heterozygosity for collagen and calcium-binding epidermal growth factor domain-containin

89 or Vegfc gene, we searched for collagen- and calcium-binding epidermal growth factor domains 1 (CCBE1

90 is region is predominantly composed of eight calcium-binding epidermal growth factor-like (cbEGF) dom

91 e tissue disorder caused by mutations in the calcium binding extracellular matrix glycoprotein fibril

92 hese conformations showed relative increased calcium binding for cTnI QAEH compared to cTnI.

93 We also observed abnormal expression of the calcium binding hair cell genes s100s and parvalbumin, a

94 ations (apo-form) to a stable structure upon calcium binding (holo-form).

95 Calcium binding induces conformational changes that like

96 The data suggest that SERCA calcium binding induces the pump to undergo a transition

97 fluorescent jRGECO1a and jRCaMP1a complexes, calcium binding is followed by rate-limiting isomerizati

98 e kinetic scheme using literature values for calcium-binding kinetics and affinities.

99 EC9-EC10, which show an EC8-9 canonical-like calcium-binding linker, and an EC9-10 calcium-free linke

100 exin V-immunogold staining revealed that the calcium-binding lipid phosphatidylserine (PS) was expose

101 of the trypsinogen activation peptide or the calcium binding loop by Ctrc is unimportant.

102 Surprisingly, mouse Ctrc poorly cleaved the calcium binding loop in all mouse trypsinogens.

103 Leu81-Glu82 peptide bond is located within a calcium binding loop, and thermodynamic stability of the

104 altered residues in or adjacent to critical calcium binding loops in the calmodulin carboxyl-termina

105 d for the ACm3AC-CaM complex showed that the calcium-binding loops of C-CaM exhibited large fluctuati

106 Furthermore, we show that direct calcium binding mediates stimulus-evoked desensitization

107 n secondary structure of the multifunctional calcium-binding messenger protein Calmodulin (CaM) as a

108 that is mediated by an interaction with the calcium-binding messenger protein, calmodulin (CaM), and

109 gamma-carboxyl glutamic acid (Gla) domain, a calcium-binding module, and prothrombin (PT) was the mos

110 agamma-crystallin domain in FgFCO1 devoid of calcium binding motif whose homologous sequences are pre

111 calcium flash activates DUOX via an EF hand calcium-binding motif and thus triggers the production o

112 ion causes an amino acid substitution in the calcium-binding motif of the extracellular cadherin (EC)

113 We also mutated the major calcium-binding motifs within the T3R domain of full-len

114 These reactions are triggered by the calcium-binding muscle protein beta-parvalbumin, which w

115 C domains as well as wild-type Thbs4 and the calcium-binding mutant interacted with Atf6alpha, induce

116 This study aims to investigate calcium-binding myeloid-related protein (MRP)-8/14 in th

117 and provide evidence that lack of secretory calcium-binding phosphoproteins accounts for the evoluti

118 est that the lack of genes encoding secreted calcium-binding phosphoproteins in cartilaginous fishes

119 We also characterize a calcium-binding pocket that is highly conserved across T

120 protection of mAb102.1F10 towards homologous calcium-binding pollen allergens.

121 EF-hand-like motif in NS2 and found that the calcium binding preferentially affects phosphorylation l

122 study revealed that the hydrogels exhibited calcium binding properties in the presence of serum-cont

123 ry and NMR spectroscopy, we investigated the calcium binding properties of a conserved (CaM1) and a d

124 response to environmental stresses, in their calcium binding properties, and in their conformational

125 an increase in synthetic marker S100A4 (S100 calcium binding protein A4) compared with contractile VS

126 etalloproteinase 9, chitinase 3-like-1, S100 calcium binding protein A8 (S100A8), S100A9, cathepsin B

127 ve cancer phenotype including increased S100 calcium binding protein A8, IL-6, IL-8, and tissue inhib

128 ein, ubiquitin c-terminal hydrolase-L1, S100 calcium binding protein B, alpha-II-spectrin breakdown p

129 tive excitatory SDH neurons that express the calcium binding protein calretinin (CR).

130 The calcium binding protein calretinin is known to be expres

131 The expression of the calcium binding protein parvalbumin (PV) has been observ

132 ctivity in inhibitory neurons expressing the calcium binding protein parvalbumin (PV) in the mouse pr

133 Calmodulin is a calcium binding protein with two lobes, N-lobe and C-lob

134 nown localization such as TcFCaBP (flagellar calcium binding protein) and TcVP1 (vacuolar proton pyro

135 matricellular protein SMOC (Secreted Modular Calcium binding protein) is conserved phylogenetically f

136 The EF-hand calcium binding protein, parvalbumin, is a major fish al

137 Secretagogin (SCGN), a hexa EF-hand calcium binding protein, plays key roles in insulin secr

138 r target of 2F11 to be Annexin A4 (Anxa4), a calcium binding protein.

139 We further show that 1q21.3-encoded S100 calcium-binding protein (S100A) family members, mainly S

140 Ca(2+) sensor proteins, calmodulin (CaM) and calcium-binding protein 1 (CaBP1), via multiple, partial

141 n, calbindin, calretinin, N-terminal EF-hand calcium-binding protein 1, cholecystokinin, reelin, or a

142 rofiling reveals an increase of the neuronal calcium-binding protein 2 (NECAB2) in diseased neurons.

143 Recently, the calcium-binding protein 39 (Cab39) has emerged as a bind

144 upregulation of the metastatic mediator S100 Calcium-binding protein A4 (S100A4) (1.78-fold, P<0.05).

145 We have previously demonstrated that S100 calcium-binding protein A4 (S100a4) is a driver of tendo

146 ion using principal component analysis, S100 calcium-binding protein A4 (S100A4) was aligned to a pri

147 Here, we found that S100 calcium-binding protein A4 (S100A4), a major metastasis-

148 se levels trigger neutrophil release of S100 calcium-binding protein A8/A9 (S100A8/A9), which binds t

149 S100 calcium-binding protein A9 (S100A9) has previously been

150 and modulates the interactions between this calcium-binding protein and the T1 domain of the Kv4.3 c

151 CSF levels of S100 calcium-binding protein B and glial fibrillary acidic pr

152 els of the astroglial injury biomarker S-100 calcium-binding protein B were also increased in players

153 marker concentrations of total tau and S-100 calcium-binding protein B were measured immediately afte

154 Total tau, S-100 calcium-binding protein B, and neuron-specific enolase c

155 Secretagogin (SCGN) is a recently discovered calcium-binding protein belonging to the group of EF-han

156 al Fibrillary Acidic Protein (GFAP) and S100 Calcium-Binding Protein beta (S100beta); and the inflamm

157 tween the sexes, using the expression of the calcium-binding protein calbindin (CB) during embryonic

158 The calcium-binding protein calbindin-D28k is critical for h

159 bility group (HMG) box) proteins require the calcium-binding protein calmodulin (CaM) for optimal nuc

160 Binding of a regulatory calcium-binding protein calmodulin (CaM) to the proximal

161 ecule, force-spectroscopy experiments of the calcium-binding protein calmodulin and explain it in a s

162 Mutations in the calcium-binding protein calsequestrin cause the highly l

163 Vps13p must be in complex with the small calcium-binding protein Cdc31p to be active.

164 The calcium-binding protein downstream regulatory element an

165 Increased levels of the calcium-binding protein neuronal calcium sensor 1 (NCS1)

166 We have discovered that the calcium-binding protein nuclebindin-1 (NUCB1) is a novel

167 Positive immunoreactivity to the calcium-binding protein parvalbumin (PV) and nitric oxid

168 basal forebrain (BF) neurons containing the calcium-binding protein parvalbumin (PV) increased broad

169 of TRN GABAergic neurons, which express the calcium-binding protein parvalbumin (PV), and are implic

170 xpresses the vesicular GABA transporter, the calcium-binding protein parvalbumin (PV), and the Kv3.3

171 by two populations of neurons containing the calcium-binding protein parvalbumin (PV): local inhibito

172 ateral hypothalamic neurons that express the calcium-binding protein parvalbumin (PVALB; LH(PV) neuro

173 lpha-Estradiol reduced the expression of the calcium-binding protein parvalbumin, decreased the integ

174 ssurance acted through the regulation of the calcium-binding protein PAT-10.

175 -spiking interneuron clusters expressing the calcium-binding protein Pvalb were identified, one co-ex

176 We used antibodies against the calcium-binding protein recoverin and the carbohydrate e

177 Nuclear expression of the calcium-binding protein S100A4 is a biomarker of increas

178 The calcium-binding protein S100A4 is expressed at elevated

179 correlated with the expression of the small calcium-binding protein S100A4.

180 ression of Cav1, which then acts through the calcium-binding protein S100P to promote metastasis.

181 In the present study the calcium-binding protein secretagogin was localized in a

182 he folding of a ribosome-bound, multi-domain calcium-binding protein stalled at different points in t

183 otassium channel interacting protein 3) is a calcium-binding protein that binds at the N terminus of

184 monstration that overexpression of S100A4, a calcium-binding protein that is frequently overexpressed

185 matrix protein 1 (DMP1) is a non-collagenous calcium-binding protein that plays a critical role in bi

186 m and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as

187 Calmodulin is a calcium-binding protein ubiquitous in eukaryotic cells,

188 Here we show that S100A11, a calcium-binding protein upregulated in a variety of meta

189 interneurons, which do not contain any known calcium-binding protein(s), kappafixed amounted to only

190 ine kinase, myosin light chain, sarcoplasmic calcium-binding protein, and hemocyanin are the most rel

191 eraldehyde-3-phosphate dehydrogenase (GPDH), calcium-binding protein, and phosphoglycerate mutase wer

192 ergic, and a quarter of these co-express the calcium-binding protein, calbindin.

193 breast cancer cells is also modulated by the calcium-binding protein, calmodulin (CaM).

194 verse genetics to test the role of the small calcium-binding protein, centrin2, in ciliogenesis.

195 fin cells, but the role of a closely related calcium-binding protein, Doc2b, remains enigmatic.

196 gene that encodes a putative histidine-rich calcium-binding protein, is the key determinant of Fhb1-

197 ically projecting neurons, which contain the calcium-binding protein, parvalbumin (PV).

198 that the selective co-expression of another calcium-binding protein, secretagogin (Scgn), separates

199 -like domain beta (DOC2B) gene encodes for a calcium-binding protein, which is involved in neurotrans

200 Calcium-binding protein-7 (CaBP7) is a phosphatidylinosi

201 This process is initiated by the calcium-binding protein-apoptosis-linked gene (ALG)-2.

202 Neurons expressing the calcium binding proteins (CaBPs) parvalbumin (PV) and ca

203 evelopmental stages of other markers such as calcium binding proteins and neuropeptides, helped the i

204 These data support the notion that calcium binding proteins are differentially distributed

205 eurodegeneration, especially when protective calcium binding proteins are lost from the cytosol.

206 The S100 calcium binding proteins S100A8 and S100A9, and their ex

207 Centrins are calcium binding proteins that belong to the EF-hand supe

208 (Ocm), a member of the parvalbumin family of calcium binding proteins, is expressed predominantly by

209 cell adhesion molecules, neuropeptides, and calcium binding proteins.

210 Calcium-binding proteins (CaBPs) such as parvalbumin are

211 The S100 calcium-binding proteins A8 (S100A8) and A9 (S100A9) eme

212 se to hyperglycemia, neutrophil-derived S100 calcium-binding proteins A8/A9 (S100A8/A9) interact with

213 thalamic neurons that do not contain typical calcium-binding proteins and do not project to other par

214 ith existing classification methods based on calcium-binding proteins and firing behavior.

215 Thus, with respect to the expression of calcium-binding proteins and neuropeptides, GINs are sur

216 cognized on the basis of their expression of calcium-binding proteins and neuropeptides, including pa

217 f inhibitory interneurons expressing various calcium-binding proteins and neuropeptides.

218 ctal cells were found to be negative for the calcium-binding proteins calbindin, parvalbumin, or calr

219 compared with the apo states of the EF-hand calcium-binding proteins calmodulin, S100B, and calbindi

220 The calcium-binding proteins calretinin (CR) and calbindin-D

221 that up to 1% of all identified multidomain calcium-binding proteins contain a similarly highly char

222 Because of the many different calcium-binding proteins distributed throughout cells, s

223 iffering densities of neurons expressing the calcium-binding proteins in specific nuclei are noted.

224 nalyze the immunohistochemical expression of calcium-binding proteins in the dorsal thalamus of Fmr1

225 of GABAergic neurons identified by distinct calcium-binding proteins may exert unique roles in the p

226 in the density of structures expressing the calcium-binding proteins parvalbumin, calbindin, and cal

227 S100A8 and S100A9 are calcium-binding proteins predominantly expressed by neut

228 In the habenula, these calcium-binding proteins revealed right-left asymmetry o

229 ne signaling, notably the heterodimeric S100 calcium-binding proteins S100a8 and S100a9.

230 Interneuron markers using calcium-binding proteins showed that LS GABAergic neuron

231 Calcium-binding proteins such as parvalbumin and calbind

232 r to derive from matrix vesicles enriched in calcium-binding proteins that are released by cells with

233 Doc2a and Doc2b are high-affinity calcium-binding proteins that interact with SNARE protei

234 n the amount of both Ca(V)1 subtypes and the calcium-binding proteins were found throughout the brain

235 calcium indicators are fusions of endogenous calcium-binding proteins whose functionality in vivo may

236 Centrins are a family of small, calcium-binding proteins with diverse cellular functions

237 ng genes for calcium management (calmodulin, calcium-binding proteins), pH regulation (V-type proton

238 that includes the AMPA receptor, integrins, calcium-binding proteins, and, surprisingly, the myelin

239 that CUL3 and its adaptor KLHL12 require two calcium-binding proteins, PEF1 and ALG2, for recognition

240 95% of the axonemal tektins, and >95% of the calcium-binding proteins, Rib74 and Rib85.5, whose human

241 s signals as inferred by the accumulation of calcium-binding proteins.

242 ng protein belonging to the group of EF-hand calcium-binding proteins.

243 In dentate granule cells, the calcium binding ratio (kappa) after complete washout of

244 ncluding the phosphatase catalytic site, the calcium-binding region 3 (CBR3) loop, the Calpha2 loop a

245 ed that multiple Ca(2+) ions bind within the calcium-binding regions, activating perforin with respec

246 identify four acidic amino acids as putative calcium-binding residues.

247 ggest a mechanism for allosteric activation: calcium binding results in partial closure and ordering

248 NF, MHC, immunoglobulin-binding Fc receptor, calcium-binding S100, matrix metalloproteinase, tissue i

249 ng helix across the activation pocket to the calcium binding site and are embedded in elements of sec

250 well as in the vicinity of the high affinity calcium binding site and the A knob polymerization pocke

251 as was seen with TBSV, CNV appears to have a calcium binding site between the subunits around the qua

252 e, reside at a significant distance from the calcium binding site in cardiac troponin C, and do not a

253 The first calcium binding site showed an antagonistic relationship

254 I are important for the stabilization (first calcium binding site) of its zymogenic form and the poss

255 the same residue, leading to the loss of the calcium binding site.

256 ity produced by the high charge density of a calcium binding site.

257 receptor signaling, while mutagenesis of the calcium-binding site abolishes Gpr126 function in vivo.

258 plicating a critical role for the A2 type II calcium-binding site and the A2A3 linker in the activati

259 ropagates from the active site region to the calcium-binding site and to the vicinity of the disulphi

260 Four of the substitutions affect the calcium-binding site in the EC4-EC5 interdomain.

261 mOLF variants carrying substitutions in the calcium-binding site that exhibit solution characteristi

262 subfamily of TRP channels and a well-defined calcium-binding site within the intracellular side of th

263 ymeric MUC5B revealed a single high affinity calcium-binding site, distinct from multiple low affinit

264 reticulin, in proximity to the high-affinity calcium-binding site, that are important for high-affini

265 alternatively spliced linker and a conserved calcium-binding site.

266 le chronological submolecular changes within calcium binding sites can bring about the detailed trans

267 Our study suggests FXIII-A calcium binding sites could be putative pharmacologicall

268 2 channel function, we altered the number of calcium binding sites in hPC2.

269 y characterizes the recently disclosed three calcium binding sites of FXIII-A concerning evolution, m

270 calcium biosensors with a reduced number of calcium binding sites per sensor.

271 ate unique structural aspects within FXIII-A calcium binding sites that give rise to functional diffe

272 idic region containing multiple low-affinity calcium binding sites.

273 ic acid residues 3394, 3556, and 3674 in the calcium binding sites.

274 cellular cadherin (EC) domains, separated by calcium binding sites.

275 fic immunotherapy based on mutation of the 2 calcium-binding sites have been developed.

276 ults suggest that the number and location of calcium-binding sites in the EF hand senses the concentr

277 main interactions and define three potential calcium-binding sites that are likely important for regu

278 ence, often featuring linkers with conserved calcium-binding sites that confer mechanical strength to

279 Synaptotagmin-1 (SYT1) is a calcium-binding synaptic vesicle protein that is require

280 at the EF-hand changes its conformation upon calcium binding, the central coiled coil forms an antipa

281 III-A(2)B(2) complex that upon activation by calcium binding/thrombin cleavage covalently cross-links

282 Furthermore, C2B inhibition is relieved by calcium binding to C2B, while the neighboring C1 domain

283 calcium-activated K(+) channels are gated by calcium binding to calmodulin (CaM) molecules associated

284 We discovered that calcium binding to calmodulin increases the binding affi

285 DP destabilize enthalpy-driven high-affinity calcium binding to calreticulin.

286 Calcium binding to either domain favors an "open" confor

287 on with the plasma membrane on activation by calcium binding to synaptotagmin.

288 It is established that calcium binding to Syt1 triggers vesicle fusion and rele

289 Contraction of heart muscle is triggered by calcium binding to the actin-containing thin filaments b

290 eable channel whose activity is regulated by calcium binding to the C-terminal domain of PC2 (PC2 Cte

291 Muscles are usually activated by calcium binding to the calcium sensory protein troponin-

292 We find that calcium binding to the EF-hand domains promotes autophos

293 NMR data demonstrate that calcium binding to the regulatory module generates subst

294 -actin (B-, C-, and M-states) in response to calcium binding to troponin and actomyosin cross-bridge

295 ated to the sensitivity and cooperativity of calcium binding to troponin C and the activation and rel

296 Cardiac muscle contraction is triggered by calcium binding to troponin.

297 Toposome is a major calcium-binding transferrin-like protein contained withi

298 Dysferlin is a calcium-binding transmembrane protein involved in membra

299 s a 1100-bp spanning region annotated to the calcium-binding tyrosine phosphorylation-regulated gene

300 However this included Cabyr, the calcium-binding tyrosine phosphorylation-regulated prote