ライフサイエンスコーパス: calcium-sensitive

1 ly correlated with cAMP accumulation and was calcium sensitive.

2 , the co-immunoprecipitation was found to be calcium-sensitive.

3 g of plant actin by human T-plastin, a known calcium-sensitive actin-crosslinking protein.

4 lin, but not Xenopus ADF/cofilin, eliminates calcium-sensitive actin-filament shortening.

5 hile testing models for CED-4 as a candidate calcium-sensitive activator of repair, we unexpectedly d

6 -type calcium channels, and secondarily, the calcium-sensitive activity of Maxi-K channels, rendering

7 Classically, P(open) is regulated by a calcium-sensitive adaptation mechanism in which lowering

8 Spermidine efflux is also calcium sensitive, and removal of external calcium incre

9 The in vivo function of CapG, a calcium-sensitive barbed end capping protein and member

10 The calcium-sensitive binding of calmodulin to myosin-1c may

11 domain, K211-I212, are required for robust, calcium-sensitive binding of S100B.

12 cell populations by cotransfection with the calcium-sensitive, bioluminescent protein aequorin and b

13 elation showed that cTn myofibrils were more calcium sensitive but less cooperative (pCa50 = 6.14, nH

14 ar glutamate levels was determined to be 39% calcium-sensitive by lowering the calcium concentration

15 Reductions of neurogranin (Ng), a calcium-sensitive calmodulin-binding protein, result in

16 These findings provide evidence that the calcium-sensitive CBL and CIPK families together with 2C

17 in eukaryotic relatives, exemplified by the calcium-sensitive channel (DeCLIC) from a Desulfofustis

18 ctor-transfected control, demonstrating that calcium-sensitive chloride channel (CLCA) expression is

19 lcium signals were studied using Fura Red or calcium-sensitive Cl(-) current.

20 An antagonist of calcium-sensitive Cl- channels (CaCC), niflumic acid, ha

21 We also show that RP2 forms a calcium-sensitive complex with the autosomal dominant po

22 50(-/-)) mice and demonstrated that both the calcium-sensitive conductance and dye influx were absent

23 in, and this interaction is regulated by the calcium-sensitive conformation of COMP/TSP5; interaction

24 e three-dimensional molecular topography and calcium-sensitive conformational changes of Connexin40 h

25 d three-dimensional molecular topography and calcium-sensitive conformational changes of individual h

26 that would not easily explain the advent of calcium-sensitive currents at embryonic day (E)18-19.

27 he current view, which has focused mainly on calcium-sensitive dehydrogenases as the target for the a

28 zers we bring two droplets, one containing a calcium sensitive dye and the other calcium chloride, in

29 actory bulb, we loaded receptor neurons with calcium-sensitive dye and imaged odorant-evoked response

30 ated hippocampal slices were loaded with the calcium-sensitive dye Calcium Green-1 and the responses

31 dies, single M1WT3 CHO cells loaded with the calcium-sensitive dye fluo-4 AM were captured; exposure

32 Further, using the calcium-sensitive dye Fluo-4, we conducted real-time ima

33 y in dopaminergic PC12 cells loaded with the calcium-sensitive dye Fura-2.

34 intracellular calcium to nicotine using the calcium-sensitive dye fura-2.

35 measured by ratiometric techniques with the calcium-sensitive dye fura-2.

36 m levels were measured using the fluorescent calcium-sensitive dye, Calcium Green-1 3000 mw dextran c

37 , measured by flow cytofluorometry using the calcium-sensitive dye, Fluo-3.

38 s (APs) from multiple dendrites using either calcium-sensitive dye, voltage-sensitive dye or both.

39 Using a calcium-sensitive dye, we observed a dramatic increase i

40 ns at single-cell and population levels with calcium-sensitive dye.

41 Advances in fluorescence microscopy and calcium sensitive dyes has led to the routine quantifica

42 video and confocal laser microscopy with the calcium-sensitive dyes fluo-3 and fura-2 were used to st

43 ard cells has previously required loading of calcium-sensitive dyes using invasive and technically di

44 parvalbumin, calbindin, calretinin, and the calcium-sensitive enzyme calcium/calmodulin-dependent ki

45 holipases A2 (cPLA2s) consist of a family of calcium-sensitive enzymes that function to generate lipi

46 nce of net plateau currents by modulation of calcium-sensitive exchange and ion channel currents.

47 that dysregulation of ceramide pathways and calcium sensitive exocytosis underlies seizures and larg

48 interacting with the doc2a gene, encoding a calcium-sensitive exocytosis regulator, a genetic intera

49 dynamics during convergent extension using a calcium-sensitive fluorescent dye and a novel confocal m

50 ; imaging of nerve terminals loaded with the calcium-sensitive fluorescent dye fluo-3 showed no signi

51 Isolated PMNs were loaded with the calcium-sensitive fluorescent dye fura-2.

52 [Ca2+](i) was assessed using the calcium-sensitive fluorescent dye fura-2.

53 in the perfused mouse heart loaded with the calcium-sensitive fluorescent dye Rhod-2.

54 Fluorescence measurements using the calcium-sensitive fluorescent dye, calcium green 5N, con

55 Calcium-sensitive fluorescent dyes indicated that such c

56 ygen-level-dependent (BOLD) and whole-cortex calcium-sensitive fluorescent measures of brain activity

57 onist-receptor interaction is measured via a calcium-sensitive fluorescent probe (fura-2) and a fluor

58 Confocal microscopy in combination with the calcium-sensitive fluorescent probe fluo-3 was used to s

59 lls were isolated, plated and preloaded with calcium-sensitive fluorescent probe, Indo-1AM.

60 A recent study in which a calcium-sensitive fluorescent protein was expressed in t

61 croscopy with the specific expression of the calcium-sensitive fluorescent protein, G-CaMP.

62 Using a calcium-sensitive fluorochrome and digital multichannel

63 Infusion of Fluo-4 AM, a calcium-sensitive fluorochrome, into the mouse circulati

64 lular calcium levels were monitored with the calcium-sensitive fluorophore fura-2 before and after tr

65 s visualized via selective expression of the calcium-sensitive fluorophore GCaMP in layer 2/3 and 5 e

66 the ROS preparations was measured using the calcium-sensitive fluorophore Quin-2.

67 naptic calcium transients were measured with calcium-sensitive fluorophores, and delayed release was

68 ng I(Ca)pre optically in boutons loaded with calcium-sensitive fluorophores.

69 rated that TnI-Y26 phosphorylation decreases calcium-sensitive force development and accelerates calc

70 le motion indicates the operation of a rapid calcium-sensitive force generator linked to the gating o

71 dc42 activation through interaction with the calcium sensitive GTPase scaffolding protein IQGAP1, mai

72 nd RetGC2) in rod and cone photoreceptors by calcium-sensitive guanylyl cyclase activating proteins (

73 Two calcium-sensitive guanylyl cyclase activating proteins (

74 ormed from connexin 38 (Cx38), and produce a calcium-sensitive (Ic) current that is inhibited by exte

75 reviously and hypothesized to be caused by a calcium-sensitive inactivation of a potassium channel.

76 We also detected calcium-sensitive increased TRPV1 activity after TRPA1 a

77 Cerebratulus lacteus were injected with the calcium-sensitive indicator calcium green dextran and/or

78 sands of neurons of the visual cortex with a calcium-sensitive indicator in vivo.

79 Measurements of [Ca]res using fluorescent calcium-sensitive indicators revealed that [Ca]res decay

80 e in endothelial cell (EC) calcium activates calcium-sensitive intermediate and small conductance pot

81 The results indicate the presence of calcium-sensitive intracellular mechanisms involved in t

82 tivators of the ATP sensitive K (K(ATP)) and calcium sensitive K (K(ca)) channel following fluid perc

83 ctivators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid

84 Although nitric oxide (NO) and calcium sensitive K+ channel (Kca) activation contribute

85 ion of calcium (Ca(2+)) sparks and transient calcium-sensitive K(+) (K(Ca)) currents by acute changes

86 duction of cAMP and subsequent activation of calcium-sensitive K+ (K(Ca2+)) channels by this second m

87 Human large-conductance voltage- and calcium-sensitive K+ (maxi KCa) channels are composed of

88 Voltage-dependent and calcium-sensitive K+ (MaxiK) channels are key regulators

89 lease of cAMP, which, in turn, activates the calcium sensitive (K(ca)) and the ATP-dependent K(+) (K(

90 Activation of calcium sensitive (K(ca)) K channels and cAMP contribute

91 while cAMP activates both the K(ATP) and the calcium sensitive (K(ca)) K(+) channel to elicit vasodil

92 cterize the role of ATP sensitive (KATP) and calcium sensitive (Kca) channel activation in hypotensio

93 vironment and involves activation of the ROS/calcium-sensitive kinase Ask1 and binding of the motor M

94 olic calcium and decreases activation of the calcium-sensitive kinase calcium-calmodulin-dependent pr

95 This helix has been postulated to serve as a calcium-sensitive latch, keeping gelsolin inactive.

96 ound that myoferlin binds phospholipids in a calcium-sensitive manner that requires the first C2A dom

97 rmation and SNARE-mediated lipid mixing in a calcium-sensitive manner.

98 regulate CDH23 trafficking/localization in a calcium-sensitive manner.

99 for their ability to bind phospholipid in a calcium-sensitive manner.

100 own that Cabin1 is associated with MEF2 in a calcium-sensitive manner; activated calmodulin binds to

101 pus extracts, Listeria tail lengths are also calcium-sensitive, markedly shortening on addition of ca

102 dent in vivo and inhibitable in vitro by the calcium-sensitive MEF2 repressor Cabin 1.

103 as been shown to be necessary for efficient, calcium-sensitive, membrane resealing.

104 [Ca2+]i were recorded using either fura-2 or calcium-sensitive microelectrodes.

105 crophage, coupling membrane capacitance with calcium-sensitive microfluorimetry.

106 Furthermore, unlike wild type G1-G3, calcium-sensitive mutants of G1-G3 acquired closed shape

107 contributed to the production of NO through calcium-sensitive nitric-oxide synthase enzymes present

108 d that this persistent firing is driven by a calcium-sensitive nonselective cation current.

109 The calcium-sensitive nuclear factor of activated T cells (N

110 f activated T cells) signaling, an important calcium sensitive pathway controlling bone formation.

111 K506, and has been implicated in a number of calcium-sensitive pathways in the nervous system, includ

112 ed phenotypes similar to those observed with calcium-sensitive, Pet- vna mutants defective in vacuole

113 ng could enhance AR phosphorylation, and the calcium-sensitive phosphatase calcineurin had opposite e

114 egulator of the hypertrophic response is the calcium-sensitive phosphatase calcineurin.

115 egulator of cardiomyocyte hypertrophy is the calcium-sensitive phosphatase calcineurin.

116 nstream signaling events are mediated by the calcium-sensitive phosphatase calcineurin; inhibition of

117 x through TRPV1 has been shown to activate a calcium-sensitive phospholipase C (PLC) enzyme and to le

118 ysferlin C2A domain and demonstrated reduced calcium-sensitive phospholipid binding.

119 Copine-6 is a calcium-sensitive phospholipid-binding protein of the ev

120 tein which we have named CSPP28 based on its calcium-sensitive phosphorylation.

121 were fused at their carboxyl terminus to the calcium-sensitive photoprotein aequorin.

122 icking-deficient CNGA3 channels based on the calcium-sensitive photoprotein aequorin.

123 Aequorin is a calcium-sensitive photoprotein originally obtained from

124 Using knock-out mice of the calcium-sensitive PKC isoforms (PKC(Ca)), we find that e

125 nduced, TRPA-1-mediated calcium influx and a calcium-sensitive PKC that signals to the transcription

126 -PMA, which does not activate PKC) recruited calcium-sensitive PKCalpha and novel PKCdelta and PKCeps

127 eries is by activation of large-conductance, calcium-sensitive potassium (BK(Ca)) channels by local C

128 The large conductance calcium-sensitive potassium (BK) channel is widely expre

129 Modulation of calcium-sensitive potassium (BK) channels by oxygen is i

130 ets, we identify N(2)O-induced inhibition of calcium-sensitive potassium (SK2) channels as a key mole

131 eurohypophysis potentiates large-conductance calcium-sensitive potassium channels (BK), contributing

132 e elevation in cytosolic calcium potentiated calcium-sensitive potassium channels (sK) activated by a

133 y between voltage-gated calcium channels and calcium-sensitive potassium channels, they can be very d

134 SL motoneurons exhibited a prominent calcium-sensitive potassium current that was not observe

135 However, cell-specific delivery of calcium-sensitive probes in vivo remains problematic.

136 switches are ancient devices for controlling calcium-sensitive processes.

137 reduction is reproduced by inhibition of the calcium-sensitive protease calpain in wild-type neurons

138 on their dephosphorylation by calcineurin, a calcium-sensitive protein phosphatase and the inhibitory

139 ts lacking tropomyosin regions 2-3 exhibited calcium-sensitive regulation in in vitro motility and my

140 In addition, the unimpaired calcium-sensitive regulation of cleaved actin indicates

141 rved at higher cellular [Ca(2+)], indicating calcium-sensitive regulation of these processes.

142 vator (CAMTA) family of proteins function as calcium-sensitive regulators of gene expression in multi

143 ochondrial calcium uniporter (MCU) and three calcium sensitive regulatory proteins (MICU1, 2 and 3).

144 studies show its calcium dependence, but the calcium-sensitive regulatory cascades have not been defi

145 d cardiac troponins C and I (Tnni3), forms a calcium-sensitive regulatory complex within sarcomeres.

146 similar to the partial assembly that engages calcium-sensitive regulatory machinery.

147 lasmic free calcium in host root hairs using calcium-sensitive reporter dyes.

148 propose a model in which otoferlin acts as a calcium-sensitive scaffolding protein, localizing SNARE

149 Colorimetric calcium-sensitive sensor films were deposited onto a DVD

150 entrations in T cells, potentially affecting calcium-sensitive signaling pathways.

151 and Asp-61), together with the intra-domain calcium-sensitive sites in villin, regulate actin depoly

152 chemically and functionally characterize the calcium-sensitive sites in villin.

153 modules constitute a dynamic and interactive calcium-sensitive structure in which a distortion at one

154 tivity assays, we show that plectasin uses a calcium-sensitive supramolecular killing mechanism.

155 ic voltage-gated calcium entry to downstream calcium-sensitive synaptic growth regulators provides an

156 w show that the tandem C2 domains of several calcium-sensitive synaptotagmin isoforms tested, includi

157 r soluble sperm factors and in turn regulate calcium-sensitive targets required for subsequent develo

158 lin D1 by post-translational modification of calcium sensitive transcription factor CREB.

159 rvations indicate that CBP can function as a calcium-sensitive transcriptional coactivator that may a

160 AC4, MITR, and Cabin1 constitute a family of calcium-sensitive transcriptional repressors of MEF2.

161 tected, despite their position distal to the calcium-sensitive tryptophan, with a volume change of +2

162 teine did inhibit the phosphorylation of the calcium sensitive tyrosine kinases PYK2 and Src, effects

163 Calcium-sensitive tyrosine kinase Pyk2 has been implicat

164 However, the activation of the calcium-sensitive tyrosine kinase PYK2, which occurred i

165 of classical PKC and the recently described calcium-sensitive tyrosine kinase PYK2.

166 Y mutation at low (<10(-7) m) calcium but is calcium-sensitive with a 1.6-fold increase at high ( app