ライフサイエンスコーパス: calicivirus

1 e characterization of a novel astrovirus and calicivirus.

2 relationship between sapoviruses and animal caliciviruses.

3 larly between those of noroviruses and other caliciviruses.

4 with those of known human and animal enteric caliciviruses.

5 enetically similar to the Sapporo-like human caliciviruses.

6 structure and gene expression in the enteric caliciviruses.

7 based upon establishing risks of exposure to caliciviruses.

8 ticles that have revolutionized the study of caliciviruses.

9 ossible rescue of uncultivable human enteric caliciviruses.

10 the start site of the subgenomic RNA in all caliciviruses.

11 rain is one of only a few culturable enteric caliciviruses.

12 /Mc114 contained features common among other caliciviruses.

13 rain is one of only a few culturable enteric caliciviruses.

14 cycle of sapoviruses and the related enteric caliciviruses.

15 r future functional studies of MNV and other caliciviruses.

16 unctions and facilitates strain diversity in caliciviruses.

17 t VP2, a minor capsid protein encoded by all caliciviruses(1,2), forms a large portal-like assembly a

18 Our data indicate that the calicivirus 3CL(pro), like PV 3C(pro), mediates the clea

19 has been previously demonstrated for feline calicivirus, a member of the Vesivirus genus, PSaV trans

20 on cruise ships, 12 (86%) were attributed to caliciviruses; among these 12, outbreak characteristics

21 main is remotely related to the P1 domain in calicivirus and hepatitis E virus, suggesting a possible

22 Previous studies on feline calicivirus and murine norovirus 1 (MNV1) demonstrated t

23 We have shown for feline calicivirus and rabbit hemorrhagic disease virus that th

24 lication were derived from studies of feline calicivirus and rabbit hemorrhagic disease virus, which

25 r divided into the following species: Feline calicivirus and Vesicular exanthema of swine virus (genu

26 me sequences are now available for 5 enteric caliciviruses and demonstrate that human and animal ente

27 Motif 1 is conserved among caliciviruses and is complementary to a sequence in the

28 sequence variation among Norwalk-like human caliciviruses and is likely to contain the determinants

29 antigenic diversity and host specificity in caliciviruses and provide a structural framework for vac

30 ectious agents (Hepatitis B Virus and Walrus Calicivirus) and demonstrated that it has higher efficie

31 supercluster, which includes picornaviruses, caliciviruses, and coronaviruses.

32 roviruses, Group A rotaviruses, Sapporo-like caliciviruses, and enteric bacteria (i.e., Salmonella, C

33 nd parasitic pathogens; serum was tested for calicivirus antibodies.

34 In humans, caliciviruses are a major cause of acute gastroenteritis

35 Host immune responses to human caliciviruses are difficult to study because of the lack

36 Caliciviruses are disseminated by the fecal-oral route a

37 Caliciviruses are known to use a novel mechanism of prot

38 The positive-strand RNA genomes of caliciviruses are not capped, but are instead covalently

39 nd demonstrate that human and animal enteric caliciviruses are phylogenetically closely related.

40 Caliciviruses are single-stranded RNA viruses that cause

41 Caliciviruses are single-stranded RNA viruses with 180 c

42 Human caliciviruses are the major cause of outbreaks of acute

43 a and also confirmed the importance of human caliciviruses as the leading cause of foodborne disease

44 ar basis of replication and pathogenesis for caliciviruses associated with diarrheal disease.

45 ncing our appreciation of the full burden of calicivirus-associated diarrhea, and it is opening new a

46 ly, we infected rabbit organoids with Rabbit calicivirus Australia-1, an enterotropic lagovirus that-

47 ve infection of rabbit organoids with Rabbit calicivirus Australia-1.

48 ric caliciviruses (ReCV) to evaluate enteric calicivirus B cell infections, in correlation to cell su

49 Bovine enteric caliciviruses (BEC) are associated with diarrhea in youn

50 ogenesis of two host-specific bovine enteric caliciviruses (BEC), the GIII.2 norovirus (NoV) strain C

51 Two genetically distinct bovine enteric caliciviruses (BECs) have been identified: the norovirus

52 e genogroups and genotypes of bovine enteric caliciviruses (BECVs) circulating in calves, we determin

53 yo-electron microscopy structures for feline calicivirus both undecorated and labelled with a soluble

54 canonical start/stop site in huNV and feline calicivirus but not in rabbit hemorrhagic disease virus.

55 nus in a clade that includes canine and mink caliciviruses but is distinct from the vesicular exanthe

56 nded RNA viruses (e.g., Echovirus 12, feline calicivirus) but degraded much faster than MS2 (inactiva

57 calf fecal samples were assayed for enteric caliciviruses by using six RT-PCR primer sets designed f

58 ralizing B-cell epitope, derived from feline calicivirus capsid protein, and a well characterized B-c

59 The first x-ray structure of a calicivirus capsid, which consists of 180 copies of a si

60 EThe highly mobile protruding domains on the calicivirus capsids are recognized by cell receptor(s) a

61 IMPORTANCE The protruding domains on the calicivirus capsids are recognized by cell receptors and

62 IMPORTANCE The major feature of calicivirus capsids is the 90 protruding domains (P doma

63 nonbacterial gastroenteritis, whereas animal caliciviruses cause various host-dependent illnesses wit

64 amino acid identity to previously described calicivirus, circovirus, adenoviruses, hepatovirus, boca

65 CV) and Caliciviridae sp. isolate hwf182cal1 calicivirus contain type 4 and type 5 IRESs, respectivel

66 However, all caliciviruses contained 3' terminal hairpins, and stem-l

67 ion Agency (EPA) is interested in preventing calicivirus contamination in treated waters used for con

68 ted with other feline RNA viruses, including calicivirus, coronavirus, herpesvirus, and feline leukem

69 y, we report the characterization of a novel calicivirus (CV), the Tulane virus (TV), which was isola

70 ization of Tulane virus (TV), a novel rhesus calicivirus (CV).

71 r set was found to be the most sensitive for calicivirus detection.

72 enterotropic lagovirus that-like many other caliciviruses-does not grow in conventional cell culture

73 st time an NTPase activity associated with a calicivirus-encoded protein.

74 None of the enteric caliciviruses except Po/Sapo/GIII/Cowden/80/US replicate

75 the prototype of the Recovirus genus in the calicivirus family, was isolated from the stools of rhes

76 rains, MD145-12 (genus Norovirus) and feline calicivirus (FCV) (genus Vesivirus), to investigate pote

77 Feline calicivirus (FCV) and murine norovirus (MNV) are used as

78 n structures of the VPg proteins from feline calicivirus (FCV) and murine norovirus (MNV), which have

79 d at the 3' end of the genomic RNA of feline calicivirus (FCV) encodes a small (12.2-kDa) minor struc

80 ach is demonstrated by the capture of feline calicivirus (FCV) from cell culture media that is expose

81 Open reading frame 2 (ORF2) of the feline calicivirus (FCV) genome encodes a capsid precursor that

82 we show how longitudinal analysis of feline calicivirus (FCV) infection in an animal rescue shelter

83 Here, we examined the effect of feline calicivirus (FCV) infection on SG accumulation.

84 The genome of feline calicivirus (FCV) is an approximately 7.7-kb single-stra

85 Feline calicivirus (FCV) nonstructural proteins are translated

86 Expression of the region of the feline calicivirus (FCV) ORF1 encoded by nucleotides 3233 to 40

87 as to identify the active form of the feline calicivirus (FCV) RNA-dependent RNA polymerase (RdRP).

88 Feline calicivirus (FCV) strains can show significant antigenic

89 engineered in which the LC region of feline calicivirus (FCV) was placed under the control of the cy

90 Feline calicivirus (FCV), a member of the Caliciviridae, produc

91 Feline calicivirus (FCV), a member of the Vesivirus genus, prov

92 observed in CRFK cells infected with Feline Calicivirus (FCV), a virus released by cell lysis, not r

93 itopes in the major capsid protein of feline calicivirus (FCV), an expression library containing rand

94 ure with that of a related vesivirus, feline calicivirus (FCV), highlighted potentially important dif

95 or feline herpesvirus type 1 (FHV-1), feline calicivirus (FCV), Mycoplasma felis, Chlamydophila felis

96 infectious acute gastroenteritis and feline calicivirus (FCV), which causes respiratory illness and

97 regenerating system was isolated from feline calicivirus (FCV)-infected cells.

98 hich includes the extensively studied feline calicivirus (FCV).

99 achment and infectious viral entry of feline calicivirus (FCV).

100 (fJAM-A) is a functional receptor for feline calicivirus (FCV).

101 We have examined the entry process of feline calicivirus (FCV).

102 s of feline coronaviruses (FCoVs) and feline caliciviruses (FCVs), respectively, and are important in

103 The capsid protein (VP1) of all caliciviruses forms an icosahedral particle with two pri

104 e we report the atomic structure of a native calicivirus from the Vesivirus genus that exhibits a bro

105 nsure that treatments are adequate to remove caliciviruses from source waters.

106 VP1 protein, including strains from all four calicivirus genera, showed the closest grouping of NB vi

107 Caliciviruses genetically related to the NLV-BEC Jena an

108 nctions as a channel for the delivery of the calicivirus genome, through the endosomal membrane, into

109 in could be provided in trans to replicating calicivirus genomes bearing a reporter gene.

110 The recent description of calicivirus genomes with 500-900nt long 5'UTRs was there

111 and lagoviruses but may also represent a new calicivirus genus.

112 Caliciviruses, grouped into four genera, are important h

113 daviruses and members of the tombusvirus and calicivirus groups provide significant new data for unde

114 We propose a mechanism for enteric calicivirus growth dependent on bile acids, ubiquitous m

115 ecular techniques to the characterization of caliciviruses has resulted in an extensive database of s

116 The human enteric caliciviruses have been assigned to 2 of these genera.

117 Since then, Norwalk-like caliciviruses have been recognized to be the most common

118 or G3BP1 integrity, suggesting that related caliciviruses have distinct effects on the stress respon

119 Previous studies on caliciviruses have identified mechanisms by which they c

120 teric caliciviruses (ReCVs) to study enteric calicivirus host cell interactions.

121 second outbreak showed that they were human calicivirus (HuCV) genogroup 1 viruses related, but not

122 powerful approach to the diagnosis of human calicivirus (HuCV) infections.

123 Human caliciviruses (HuCVs) are the major cause of outbreaks o

124 To define the role of human caliciviruses (HuCVs) in severe childhood gastroenteriti

125 of similar assays for the detection of human caliciviruses (HuCVs).

126 our study provides the first insight on how caliciviruses impair stress granule assembly by targetin

127 .68% reduction in virus titer against Feline calicivirus in a surface time-kill test using ready-to-u

128 were essential for growth of porcine enteric calicivirus in cell culture in association with down-reg

129 e genomes of novel species of astrovirus and calicivirus in cloacal swabs of ruddy turnstones (Arenar

130 walk virus (NV), a reference strain of human calicivirus in the Norovirus genus of the family Caliciv

131 uent coinfection of HAstV with rotavirus and caliciviruses in childhood diarrhea complicates the epid

132 Although laboratory confirmation of caliciviruses in stool samples was not attempted in most

133 Enteric caliciviruses in the genera Norovirus and Sapovirus are

134 unologic functions and pathogenesis of human caliciviruses in the Norovirus and Sapovirus genera is h

135 From such studies, it was proposed that caliciviruses induce apoptosis to facilitate the dissemi

136 f Health has allowed for the confirmation of calicivirus infection among patients involved in epidemi

137 nfectious peritonitis and virulent, systemic calicivirus infection are caused by certain types of fel

138 The control of outbreaks of calicivirus infection in high-density, high-throughput p

139 volution of our understanding of immunity to calicivirus infection, using Norwalk virus as the protot

140 assays and dissecting the immune response to calicivirus infection.

141 he high sequence identity between identified calicivirus IRESs and specific picornavirus IRESs sugges

142 These calicivirus IRESs occur in a single phylogenetic branch

143 Feline calicivirus is a major causative agent of respiratory di

144 identity of the complete NB VP-1 with other caliciviruses is low, varying between 14.6 and 26.7%.

145 Norwalk virus (NV), the prototype human calicivirus, is the leading cause of nonbacterial acute

146 Norwalk virus, a noncultivatable human calicivirus, is the major cause of epidemic gastroenteri

147 that VP2, a protein apparently unique to the caliciviruses, is essential for productive replication t

148 thus far, suggesting that the VPg protein of caliciviruses, like those of picornaviruses and potyviru

149 ith cytoplasmic membrane vesicles containing calicivirus-like particles of 25 to 40 nm in diameter.

150 The calicivirus minor capsid protein VP2 is expressed via te

151 The conserved calicivirus motifs were identified in the nonstructural

152 occurs efficiently on subgenomic bicistronic calicivirus mRNAs, enabling synthesis of minor capsid pr

153 is process in vitro on two model bicistronic calicivirus mRNAs.

154 Among caliciviruses, NB virus shows amino acid identities of 1

155 Norwalk-like caliciviruses (Noroviruses) cause over 90% of nonbacteri

156 All cleavages by calicivirus or PV proteases separated the C-terminal dom

157 Eleven of the 12 calicivirus outbreaks were attributed to noroviruses, 7

158 herein make TV a valuable model for studying calicivirus pathogenesis and replication.

159 Porcine enteric calicivirus (PEC) causes diarrhea and intestinal lesions

160 Porcine enteric calicivirus (PEC) is associated with diarrhea in pigs, a

161 A porcine enteric calicivirus (PEC), strain Cowden in the family Calicivir

162 A porcine enteric calicivirus (PEC), strain Cowden in the genus Sapovirus

163 Porcine enteric calicivirus (PEC/Cowden) causes diarrhea in pigs, grows

164 Among caliciviruses, PEC has the highest amino acid sequence i

165 f new molecular diagnostic methods has shown caliciviruses (previously referred to as the Norwalk fam

166 ) were subsequently screened using universal calicivirus primers, and 17 SaV strains were confirmed b

167 he RdRp activity of the norovirus and feline calicivirus Pro(-)Pol enzymes were compared and found to

168 ovides the first structural view of a native calicivirus-protein receptor complex and insights into t

169 These comparative structural studies of caliciviruses provide a functional rationale for the uni

170 AR) as the entry receptor for rhesus enteric calicivirus (ReCV) isolate FT285 and demonstrated that c

171 Here, we used HuNoV and rhesus enteric caliciviruses (ReCV) to evaluate enteric calicivirus B c

172 human noroviruses (HuNoV) and rhesus enteric caliciviruses (ReCV).

173 group antigen (HBGA) binding, rhesus enteric caliciviruses (ReCVs) are viable surrogate models for Hu

174 Particularly, rhesus enteric caliciviruses (ReCVs) display remarkable similarities, i

175 attachment receptors, we used rhesus enteric caliciviruses (ReCVs) to study enteric calicivirus host

176 ular proteins, and its function in the human calicivirus replication cycle is not known.

177 ype strain of a group of noncultivable human caliciviruses responsible for epidemic outbreaks of acut

178 is the prototype strain of a group of human caliciviruses responsible for epidemic outbreaks of acut

179 may play a role in initiating translation on calicivirus RNA through unique protein-protein interacti

180 Pg may function in translation initiation on calicivirus RNA.

181 s-like type 2 IRESs, whereas ruddy turnstone calicivirus (RTCV) and Caliciviridae sp. isolate hwf182c

182 tone astrovirus (RtAstV) and Ruddy turnstone calicivirus (RTCV), respectively.

183 Studies of feline and murine caliciviruses show that VP2 may help deliver the viral g

184 EPA can make regulatory decisions regarding caliciviruses, significant information and technology ne

185 virus (HuNoV) cell culture system surrogate, caliciviruses still represent valuable research tools fo

186 We used two distinct calicivirus strains, MD145-12 (genus Norovirus) and feli

187 hore and highlights the utility of targeting calicivirus structural proteins to restrict viral replic

188 humans and map immunological function onto a calicivirus structure.

189 triking differences between MNV and previous calicivirus structures are that the protruding domain is

190 ite and major immunodominant epitopes in all caliciviruses studied thus far, is quite different from

191 aliciviridae sp. isolate yc-13 and six other caliciviruses suggested that they contain picornavirus-l

192 re structural similarity to SMSV4, an animal calicivirus, suggesting a closer relationship between sa

193 ion by local or state health departments for calicivirus testing.

194 press the capsid protein of Norwalk virus, a calicivirus that causes epidemic acute gastroenteritis i

195 Tulane virus (TV) is a newly reported calicivirus that was isolated from stool samples of capt

196 m is presently the only in vitro model among caliciviruses that cause gastrointestinal disease, inclu

197 Often, cell culture-adapted caliciviruses that rapidly replicate in conventional cel

198 ursors and products identified in studies of caliciviruses that replicate in cell culture systems.

199 is the first report of an attenuated enteric calicivirus, the induction of diarrhea, and intestinal l

200 As observed for other caliciviruses, the PSaV genome was found to be covalentl

201 nd to date it is the only cultivable enteric calicivirus (tissue culture-adapted [TC] PEC/Cowden).

202 investigate potential strategies used by the caliciviruses to inhibit cellular translation.

203 e used as a model to examine the dynamics of calicivirus transmission and evolution in such environme

204 e features of MNV suggest that at least some caliciviruses undergo a capsid maturation process akin t

205 Many viruses, including the related feline calicivirus, use terminal sialic acids (SA) as receptors

206 The precise role of the calicivirus VPg core in virus replication remains to be

207 his relative position is conserved among all calicivirus VPg proteins examined thus far, suggesting t

208 s into the novel protein-primed mechanism of calicivirus VPg-dependent translation initiation.

209 in young cats, and virulent, systemic feline calicivirus (vs-FCV) causes a highly fatal disease in ca

210 criteria for inclusion in the present study, caliciviruses were detected in 184 (81%) by reverse-tran

211 erformance for detection of RV-A, HAstV, and calicivirus, while the sensitivity for HAdV and HEV was

212 The public health impact of caliciviruses will not be fully appreciated, nor will in

213 been exploiting endemic infection of feline calicivirus within five geographically distinct househol