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1 s with the bilirubin excretion into the bile canaliculi.
2 mice had 33 to 45% fewer, and more tortuous, canaliculi.
3 obule and established new junctions with the canaliculi.
4 gular clusters with shorter and disorganized canaliculi.
5  of tooth loci and the development of dorsal canaliculi.
6 sports bile salts from hepatocytes into bile canaliculi.
7 boxyfluorescein (6-CF) and secreted into the canaliculi.
8 s, and ultrastructural abnormalities of bile canaliculi.
9 reased secretion of fluorescent PC into bile canaliculi.
10 mutant protein to reach the membrane of bile canaliculi.
11 llular fibrosis, and dilated, misshapen bile canaliculi.
12 rmal, with irregular lacunar walls and fewer canaliculi.
13 here all of the flow is channeled into fewer canaliculi.
14 se staining along dendrites in the osteocyte canaliculi.
15  cytoplasmic tubulovesicles to the secretory canaliculi.
16 opy also revealed structures resembling bile canaliculi.
17 lumina, reminiscent of those seen about bile canaliculi.
18 cal membrane of the hepatocyte into the bile canaliculi.
19 of damage to transgenic hepatocytes and bile canaliculi.
20 y transforming into blebs or continuing into canaliculi.
21 phery of inflammatory foci or in the biliary canaliculi.
22 rete fluorescein diacetate into visible bile canaliculi.
23 icus was noted infrequently and only in bile canaliculi.
24 d translocates phosphatidylcholine into bile canaliculi.
25 tocytes and consequently less secretion into canaliculi.
26 y higher accumulation of CDF in cells + bile canaliculi (32.3 +/- 2.5 versus 24.4 +/- 4.3 pmol/mg of
27  (52 of 69 [75%]) and status of the lacrimal canaliculi (54 of 69 [78%]), nasolacrimal ducts (48 of 6
28 eculae [6], or bone canaliculi (i.e., dorsal canaliculi) [7].
29 tion of the homeostasis of the intercellular canaliculi, a specialized apical domain of the acinar ce
30 cells as shown by impaired formation of bile canaliculi, absence of polarity, and reduced secretion o
31 on the viability of tubulovesicles/secretory canaliculi and by regulating chloride secretion in parie
32 anize their apical membrane domain into bile canaliculi and ducts, which are not accessible to circul
33 h severely impaired development of secretory canaliculi and few tubulovesicles but normal apical micr
34 y, these mutants develop defects in the bile canaliculi and have marked biliary paucity, suggesting t
35 tion (flow) and diffusion in individual bile canaliculi and in interlobular bile ducts of intact live
36 wever, Atp4a(-/-) parietal cells had dilated canaliculi and lacked typical canalicular microvilli and
37 haped bacteria predominantly located in bile canaliculi and occasionally in bile ducts.
38 estingly, toothless anteaters present dorsal canaliculi and preserve intact tooth innervation, while
39 ovided a trans-epithelial shunt between bile canaliculi and sinusoids by which bile constituents leak
40 liver AP (resulting from its relocation from canaliculi and the acidic milieu) might promote hyper-ad
41 ion, the tubulovesicles fuse with the apical canaliculi and the HK-ATPase is incorporated into the ap
42 rate lumina at cell-cell contact sites (bile canaliculi) and orient MTs horizontally.
43 tures had epithelial morphology, showed bile canaliculi, and expressed albumin messenger RNA (mRNA).
44 ver, secreted from hepatocytes into the bile canaliculi, and subsequently stored in the gall bladder.
45             In WIF-B9 cells, which lack bile canaliculi, apical ABC transporters colocalized with tra
46 ggesting cellular activation, whereas apical canaliculi appeared relatively nonactivated.
47                                              Canaliculi are linked to smaller channels of ~40 nm diam
48 nae had more severe disruptions of osteocyte canaliculi around linear microcracks.
49   Electron microscopy showed developing bile canaliculi at 1 day.
50 otropically to generate a 3D network of bile canaliculi (BC).
51 otropically, generating a 3D network of bile canaliculi (BC).
52 t, organize their luminal surfaces (the bile canaliculi; BC) between their lateral membranes, and, wh
53 ed as biliary glycoprotein 1 (BGP1) via bile canaliculi (BCs).
54 normally processed and expressed at the bile canaliculi, but their stability was reduced.
55 or no effect on ABCB4 expression at the bile canaliculi caused a decrease (F357L, T775M, and G954S) o
56 gastric proton pump and alters the secretory canaliculi, causing hypochlorhydria and hypergastrinemia
57 to tissue localization in the placenta, bile canaliculi, colon, small bowel, and brain microvessel en
58 pidly in CP-treated animals, and hybrid bile canaliculi developed even 1 day after cell transplantati
59 lized tendon regions, where ~100 nm diameter canaliculi emanating from cell (tenocyte) lacunae surrou
60 ntegrated into hepatic cords, formed biliary canaliculi, expressed hepato-specific enzymes, accumulat
61 roxide solution preserved a dense network of canaliculi extending from the apical to the upper latera
62 omal enlargement and defective intracellular canaliculi formation observed in Trpml1(-/-) parietal ce
63 lization of polarity proteins, impaired bile canaliculi formation, and loss of microvilli.
64 ent a suitable in vitro system to study bile canaliculi formation, bile drainage and how different ce
65 egenesis, with hybrid gap junctions and bile canaliculi forming over 3 to 7 days after cell transplan
66 manifested by sequential progression of bile canaliculi from small structures to a fully branched net
67 h roots [5, 6], bone trabeculae [6], or bone canaliculi (i.e., dorsal canaliculi) [7].
68 icroscopy revealed dilated and tortuous bile canaliculi in KO livers along with decreased canalicular
69 eas it rapidly appeared in the abnormal bile canaliculi in LKB1(-/-) mice, confirming that junctional
70 w density around osteocyte lacunae and their canaliculi in osteostracan bone.
71 low, which is normally expressed in the bile canaliculi in the liver.
72 arization and outward on depolarization (via canaliculi in the protein that bring the extracellular a
73 tional, consistently draining bile from bile canaliculi into the bile duct.
74 espite work suggesting that fluid flow along canaliculi is a dominant physical cue sensed by osteocyt
75 ein levels, minor changes to the TJ, dilated canaliculi, lower microvilli density, and aberrant radix
76 c fatty liver disease, such as decay of bile canaliculi network and ductular reactions.
77                         We compared the bile canaliculi network in the organoids incubated with versu
78  hepatocyte organoids with a functional bile canaliculi network that retain morphological features of
79 ids spontaneously assemble a functional bile canaliculi network, extending from the surface to the in
80                       In the liver, the bile canaliculi of hepatocytes are connected to intrahepatic
81                                     The bile canaliculi of hepatocytes contract spontaneously, and it
82 ter hepaticus, infects the intrahepatic bile canaliculi of mice, causing a severe chronic hepatitis c
83 distribution of the ecto-ATPDase in the bile canaliculi of the chicken liver.
84 of filamentous actin in hepatocytes and bile canaliculi of the ischemic lobes compared with the HSP27
85 t extrudes phosphatidylcholine into the bile canaliculi of the liver.
86 pun glass hair syndrome," "pili trianguli et canaliculi," or "cheveux incoiffables" is a rare anomaly
87 sent focally, was manifested as dilated bile canaliculi, partial loss of microvilli, and retention of
88 rastructural characteristics, including bile canaliculi, peroxisomes, and glycogen granules, when mai
89 membranes, bile acids are transported in the canaliculi primarily by diffusion.
90 d cell differentiation and formation of bile canaliculi, probably through an effect on hepatocyte nuc
91 on of the mandible and underlines the dorsal canaliculi sensorial role in the context of mediolateral
92 iations between tenocytes, tenocyte lacunae, canaliculi, small channels, collagen, and mineral sugges
93                                  Lacunae and canaliculi spaces of osteocytes are remarkably well pres
94 me, came as no surprise since porosome-like "canaliculi" structures for secretion from human platelet
95 many of the functions exhibited by bona fide canaliculi, such as sequestering sodium fluorescein.
96    The organoids organized a functional bile canaliculi system, which was disrupted by cholestasis-in
97 franuclear structure was composed of slender canaliculi that collected near or streamed to plasmalemm
98   The hepatocyte's apical surface forms bile canaliculi that transport bile to the hepatic ducts.
99  and colocalized with clathrin around apical canaliculi, the sites that control acidification of the
100                Here we present evidence that canaliculi--the submicrometre-sized channels that interc
101 form dendritic processes that travel through canaliculi to make contact with other osteocytes and cel
102 ic organoids; development of functional bile canaliculi was imaged live.
103 .e., increase in the mature form at the bile canaliculi, was obtained by cell treatments with cyclosp
104 nduced a significant expansion of the apical canaliculi, whereas depletion at late embryonic stages r
105 lar network and secrete metabolites into the canaliculi, which are then transported into the biliary
106 vealed impaired bile secretion into the bile canaliculi, which was secondary to loss of canalicular b
107 complex of segmented cisternae and branching canaliculi with clustered mitochondria.
108 sess structural polarity and functional bile canaliculi with normal differentiated function.
109  required a Lester-Jones tube despite patent canaliculi, with a success rate of 90%.

 
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