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1 n studies and publicly available datasets in cancer genomics.
2 m, passenger mutations is a key challenge in cancer genomics.
3 y relevant features for survival analysis in cancer genomics.
4 l translocations is an important question in cancer genomics.
5 e SVs, focusing on applications in human and cancer genomics.
6 r diverse fields, including gene therapy and cancer genomics.
7 ublicly available through the cBioPortal for Cancer Genomics.
8 tissues is one of the biggest challenges in cancer genomics.
9 a cohort of tumors is a challenging task in cancer genomics.
10 put to many important downstream analyses in cancer genomics.
11 enable more detailed downstream analyses in cancer genomics.
12 thms limits the implementation and uptake of cancer genomics.
13 cancer causation through large-scale global cancer genomics.
14 r Research Project GENIE, and cBioPortal for Cancer Genomics.
15 mes in clinical samples using cBioPortal for Cancer Genomics.
16 cross the breadth of Mendelian disorders and cancer genomics.
17 use the CGC to investigate key questions in cancer genomics.
18 ranslational effects of genetic mutations in cancer genomics.
19 ts in both risk groups, which is violated in cancer genomics.
20 isASE has potential for wide applications in cancer genomics.
21 t across human cancers is a key challenge in cancer genomics.
22 ulations within tumors is a key challenge in cancer genomics.
23 up unprecedented opportunities to transform cancer genomics.
24 ntal problem for statistical methods used in cancer genomics.
25 results may help to guide the next stage of cancer genomics.
30 ly, we will also discuss how the advances in cancer genomics and cancer modeling will influence each
36 article highlights the technology underlying cancer genomics and examines the early results of genome
38 ation changes are integral to all aspects of cancer genomics and have been shown to have important as
40 use of in situ single cell-based methods in cancer genomics and imply that chemotherapy before HER2-
43 e visualization of longitudinal clinical and cancer genomics and other molecular data in patient coho
45 cers represent a unique case with respect to cancer genomics and precision medicine, as the mutation
46 to diversifying the knowledge base of breast cancer genomics and provides insights into the disease e
47 aspirates, together with recent advances in cancer genomics and single-cell molecular analysis, have
48 lacement therapy and risk for breast cancer, cancer genomics and targeted therapies, short- and long-
51 provide an overview of the current state of cancer genomics, appraise the current portals and tools
52 genetic landscape of most cancer types, and cancer genomics approaches are driving new insights into
53 map healthy organs and previous large-scale cancer genomics approaches focused on bulk sequencing at
54 ovided practical knowledge on structural and cancer genomics approaches, as well as an exclusive plat
55 encing has been widely used for personal and cancer genomics as well as in various research areas.
56 mproved understanding of population-specific cancer genomics, as well as translation of those finding
63 ted versions in CWL and on the Seven Bridges Cancer Genomics Cloud platform can be obtained by contac
64 ncer Gateway in the Cloud, and Seven Bridges Cancer Genomics Cloud) provide access and availability t
65 n Bridges Genomics implementation of the NCI Cancer Genomics Cloud, which provides graphical interfac
72 en tested the predictions of our model using cancer genomics data and confirmed that many passengers
73 t using drug-response data, multidimensional cancer genomics data and genome-wide association study d
74 lso applied the human interactome network to cancer genomics data and identified several interaction
75 ed tools to display, investigate and analyse cancer genomics data and its associated clinical informa
77 pharmacogenomics data resources such as pan-cancer genomics data for cancer cell lines (CCLs) and tu
78 r hosts a growing body of publicly available cancer genomics data from a variety of cancer types, inc
80 impute drug response in very large clinical cancer genomics data sets, such as The Cancer Genome Atl
81 t for this model in cancer age-incidence and cancer genomics data that also allow us to estimate the
83 The algorithm is fast, broadly applicable to cancer genomics data, is of immediate use for prioritizi
84 isualization tools enable the exploration of cancer genomics data, most biologists prefer simplified,
85 onfounding effects of technical artifacts in cancer genomics data, our study emphasizes the need to s
92 ing costs in DNA sequencing technology, rich cancer genomics datasets with many spatial sequencing sa
93 We test the method on all available TCGA cancer genomics datasets, and detect multiple previously
98 Diagnostic and therapeutic advances based on cancer genomics developed during a time when it was poss
106 tools have, along with the rapid progress of cancer genomics, generated an increasingly complex under
107 technology has produced a transformation in cancer genomics, generating large data sets that can be
108 tumors or cultured samples are superior for cancer genomics has been a longstanding subject of debat
109 come more important because federally funded cancer genomics has been centralized under The Cancer Ge
110 rical view of how increased understanding of cancer genomics has been translated to the clinic and di
112 se of normal tissue data for the analysis of cancer genomics has primarily focused on the paired anal
116 of the importance of evolutionary theory to cancer genomics have led to a proliferation of phylogene
117 tions of protein-coding genes are a focus of cancer genomics; however, the impact of oncogenes on exp
121 ir tumor genetics with the goal of utilizing cancer genomics in the clinical management of pancreatic
123 ver quality, utility, and safety of LDTs for cancer genomics, including tests marketed directly to co
130 One of the most important recent findings in cancer genomics is the identification of novel driver mu
135 is evident that the translation of emerging cancer genomics knowledge into clinical applications can
136 ng technologies has transformed the field of cancer genomics, leading to the identification of geneti
137 These results identify the convergence of cancer genomics, mitochondrial priming and GCT evolution
139 pathway analysis has been a powerful tool in cancer genomics, our knowledge of oncogenic pathway modu
140 Given the complexity and diversity of the cancer genomics profiles, it is challenging to identify
141 the unprecedented conjunction of large-scale cancer genomics profiling of tumor samples in The Cancer
142 and case breast cancer datasets from the NCI cancer genomics program - The Cancer Genome Atlas (TCGA)
144 Based on this analysis, we suggest that cancer genomics projects such as The Cancer Genome Atlas
156 bally distinct patients, we generate a large cancer genomics resource for sub-Saharan Africa, identif
157 vo RNAi screens and illustrate how combining cancer genomics, RNA interference, and mosaic mouse mode
158 t institutions performing NGS sequencing for cancer genomics should incorporate the step of merging M
159 , we review the key historical milestones in cancer genomics since the completion of the genome, and
162 ES) is widely utilized both in translational cancer genomics studies and in the setting of precision
163 r heterogeneity, tumor samples collected for cancer genomics studies are often heavily diluted with n
167 s a significant technical challenge for most cancer genomics studies performed at less than 100x mean
168 patterns and driver pathways in large-scale cancer genomics studies, and it may also be used for oth
169 e advantages of ExaLT on data from published cancer genomics studies, finding significant differences
171 iety of cancers as identified in large-scale cancer genomics studies, provide new interfaces for expl
175 heterogeneity in several key applications in cancer genomics such as immunogenicity, metastasis, and
176 This article discusses several areas within cancer genomics that are being transformed by the applic
177 ghlight key discoveries and resources within cancer genomics that were previously inaccessible with p
178 or Ags can be identified by directly linking cancer genomics to cancer immunology and immunotherapy.
179 the current challenges for applying prostate cancer genomics to clinical management, this review will
180 ve adequate background knowledge of clinical cancer genomics to design meaningful radiogenomics proje
181 rm initially designed for use in research on cancer genomics to enable its use in research on SARS-Co
185 ly structured will primarily fund efforts in cancer genomics with longer-term goals of advancing prec
186 A sequencing has revolutionized the study of cancer genomics with numerous discoveries that are relev
187 provide insight into the landscape of breast cancer genomics with the genomic characterization of tum
188 mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, cla
189 Short-read sequencing is the workhorse of cancer genomics yet is thought to miss many structural v