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1 ay have an adaptive advantage over those who cannot.
2 hronize their movements in ways that novices cannot.
3 while changes in predator-prey interactions cannot.
4 emaining absorption surface of the intestine cannot absorb enough macronutrients, micronutrients, and
6 GxE genome-wide are nascent and, as we show, cannot accommodate general environment variables, modest
12 llows for rapid staining, but these sections cannot accurately represent three-dimensional structures
13 bserve that all the state-of-the-art methods cannot achieve an ideal accuracy for overlap detection (
14 but its diagnostic accuracy is limited as it cannot adequately distinguish between true tumor progres
17 putational cost, existing region-based tests cannot analyze hundreds of thousands of samples while ac
20 ue to sp(2) carbon-conjugated frameworks and cannot be accessible by imine-linked frameworks, amorpho
21 3D perovskite AMX(3) structure because they cannot be accommodated in the cubo-octhedral cage (do no
22 ing the transition toward circularity, which cannot be achieved by technology improvements alone-the
25 x biological regulatory mechanisms when this cannot be achieved solely through experimental approache
26 luorescence imaging of kidney cancers, which cannot be achieved with hepatobiliary- and glomerular-cl
27 antagonizing platelet integrin alphaIIbbeta3 cannot be achieved without compromising hemostasis, thus
31 the fluorescent particles can diffuse, they cannot be applied to situations in which this region is
33 of choice when dealing with matrix data that cannot be arranged into a trilinear three-way array, tha
35 also suggests that ATP and NAD(P)H balancing cannot be assessed in isolation from each other, or even
36 surgical intervention's impact on mortality cannot be assessed in this study, as it would need to be
40 ent anti-biofilm activity of Bald's eyesalve cannot be attributed to a single ingredient and requires
42 Treg) during coculture assays, features that cannot be captured by using surrogate cell lines or anim
43 In humans, clinical manifestation of tics cannot be captured via functional imaging due to motion
47 , sIPV products from different manufacturers cannot be compared, and the relationship between antigen
50 liferation, and note that these observations cannot be conducted within previous continuum models of
51 suming and more often is only indicative and cannot be considered confirmative as it is susceptible t
53 icates that the development of mental health cannot be considered without consideration of children i
55 that when population structure is recent, it cannot be corrected using principal components of common
58 specific adverse effects of ROS1 inhibition cannot be deconvoluted from the toxicity profiles of the
60 such as remdesivir and reconvalescent serum cannot be delivered orally(2,3), making them poorly suit
61 cancer screening, the number of cancers that cannot be detected with mammography is substantial, espe
62 ctions are difficult to analyze because they cannot be determined by comparing the energies of compet
65 that the biodegradation performance in soils cannot be directly assessed by measuring the expression
67 hnical limitation of estimating g(m) , which cannot be directly measured, and (iv) how g(m) responds
68 le costs on society; however, their benefits cannot be directly observed and are currently understood
69 on structure and transcriptional states that cannot be discerned from bulk measurements, establishing
71 a 1:1 protein-lipid complex, where the lipid cannot be displaced by detergent from the highly protect
72 toxin A gene (sea) causes food poisoning and cannot be distinguished from non-pathogenic strains by t
73 ble elements from which reliable conclusions cannot be drawn, and therefore has made the decision to
74 f cryptic lineages within the upwelling zone cannot be easily accounted for by environmental heteroge
76 probes are limited in scope, though, as they cannot be easily distinguished in biological environment
80 We show that the striped fibrillar pattern cannot be easily predicted from the interactions between
89 However, traditional chemical inhibitors cannot be experimentally applied with spatiotemporal pre
90 g learning and memory; however, this process cannot be explained by a simple linear trajectory of tra
91 ifts observed in several FLE conditions that cannot be explained by alternative (temporal) models of
93 duced iodine emissions from natural seawater cannot be explained by chemical losses of I(2) or hypoio
94 s a lower genotype-derived heritability that cannot be explained by inclusion of milder cases and a h
95 2) the dapagliflozin-induced increase in EGP cannot be explained by the increase in plasma glucagon o
97 deep low-stability layer in the polar region cannot be explained by vertical convection in the middle
98 ovir toxicity in patients taking ART for HIV cannot be explained solely on the basis of off-target in
99 ral rearrangement in the process XS -> XS(-) cannot be explained using the values of the electron det
102 differentiated for effective sensing, which cannot be fulfilled by common PDs with a broadband respo
103 As yet, this multi-length-scale complexity cannot be fully captured by atomistic simulations, and t
104 ted that annual phytoplankton biomass cycles cannot be fully understood from environmental properties
105 ctions and network architectures exists, but cannot be fully understood without attention to the envi
107 mary pseudotumor cerebri, in which the cause cannot be identified (also known as idiopathic intracran
108 racteristics with mammalian enteric glia but cannot be identified by the expression of canonical glia
109 ss weak magnetic remanence (Fe(3) O(4) ), or cannot be implemented in nanofabrication schemes (NdFeB)
110 challenge for cells is that these objectives cannot be independently optimized, and maximizing one of
111 heir conditional informativeness for disease cannot be inferred from their accuracy in predicting reg
116 xplain phenotypes of genetic diseases, which cannot be obtained by transcript information alone.
117 d variance, scores, and other results, which cannot be obtained in the conventional cross-validation.
118 urface response (i.e., heterogeneity), which cannot be obtained solely by an electrochemical means.
120 ods for SCD are time-consuming, complex, and cannot be performed at point-of-care (POC) and home sett
121 gh the generation of mice in which eIF2alpha cannot be phosphorylated specifically in Schwann cells.
123 the success or failure of a given structure cannot be predicted by quality metrics such as resolutio
126 ks are not stabilized, and new origin firing cannot be prevented, leading to the accumulation of DNA
127 dels, we demonstrate that these observations cannot be produced by previously proposed horizontal ext
128 fore a full range of template concentrations cannot be quantified accurately with these methods alone
130 hydrogels with a desirable network structure cannot be readily achieved using conventional polymeriza
131 g of complex genomic regulation in vivo that cannot be readily investigated through standard methodol
132 ow is well suited to biological samples that cannot be readily isotope labeled, including plants, mam
137 not ideal because often the null hypothesis cannot be rejected simply due to limited statistical pow
140 to inappropriate post-harvest processing and cannot be removed in the subsequent chocolate-manufactur
141 ng that this property is highly variable and cannot be represented by a single value based on the AO-
143 c behavior observed in synaptic transmission cannot be reproduced in a standard kinetic model without
147 ls measured in the general population, risks cannot be ruled out due to the potential for population
148 ity of neuroinvasiveness of the virus, which cannot be ruled out given the expression of low levels o
150 uire field experts to create them, and often cannot be shared outside the lab due to medical regulati
153 ange and human response and argue that these cannot be successfully addressed without an understandin
156 chitin into two aromatic NCCs that currently cannot be synthesized from chitin via any chemical proce
157 e access to the properties of compounds that cannot be synthesized in single-phase form, sparing cost
158 -50% or less in many cohorts, a good ranking cannot be taken to imply that the gene or disease at ran
161 lly polar, it is heavily disordered and this cannot be the sole reason for the ferroelectricity.
162 replicate in these mosquitoes and therefore cannot be transmitted to people even in the unlikely eve
164 mena that can be surprisingly rich and often cannot be understood by studying only the individual con
167 ality assumption are readily available, they cannot be used directly because the included studies hav
171 ber of core single nucleotide variants alone cannot be used to infer cross-transmission in M. abscess
172 al intensity, such as those for well plates, cannot be used to quantify signal from most of these dev
173 mice and all existing humanized mouse models cannot be used to test the efficacy of vaccines expressi
174 re inefficient because lower-quality samples cannot be used, and they assume individuals are identifi
177 nitive or reward-related impairments, yet it cannot be wholly related to one or the other process and
180 rupt editing in vitro, suggesting that PPR65 cannot bind modified bases due to differences in the str
182 We argue that statistical measures alone cannot capture all structural aspects of LCRs and recomm
183 method for analyzing rational process models cannot capture an important constraint on resource alloc
184 y are usually very successful but inherently cannot capture the quantum-optical nature of the process
185 ch is composed of a grating and line sensor, cannot capture the spectral behavior from noise to stabl
190 When we face ambiguous images, the brain cannot commit to a single percept; instead, it switches
192 rly studies suggested that Fe(III) complexes cannot compete with Gd(III) complexes as T(1) MRI contra
193 y, AID(S38A/S38A)UNG(-/-) mouse B cells also cannot complete CSR or affinity maturation despite accum
195 ks the ability to initiate transcription and cannot consistently transcribe through long DNA sequence
197 otential value of refined tools of this sort cannot currently be made because such an assessment woul
198 ersistently even if its cortical contraction cannot deform a near-rigid ECM, but then the contraction
199 le sulfate to oxidize the sub-arc mantle and cannot deliver (34)S-enriched sulfur to produce the posi
201 unts in people's vaccine decision-making, it cannot determine whether different degrees of severity i
205 us on prioritization of candidate genes, and cannot directly infer the specific functional effects of
206 hermore, we show that predictive information cannot distinguish between organisms that are adapted to
207 on about leukaemia biology and prognosis, it cannot distinguish which mutations occur in the same clo
208 its interactions, but most in vitro studies cannot duplicate the unique spatial arrangement of cMyBP
209 capturing a subset of cleansing effects, but cannot easily handle cleansing effects in non-moral, non
210 , required for NMR excitation and detection, cannot easily penetrate the battery casing due to the sk
211 bit structural and molecular alterations and cannot effectively compensate for fluid extravasation an
214 lysogenic), type I CRISPR-Cas immune systems cannot eliminate the phages from the bacterial populatio
215 rphological measurements of the root systems cannot entirely explain variations in citrate-enhanced u
217 iring more anti-VEGF injections; however, we cannot exclude that the RNFL thinning may be secondary t
218 g extends classical computing means that one cannot expect arbitrary simulations to be sped up by a q
219 vealed that carrier-mediated transport alone cannot explain the experimentally determined auxin distr
220 ulk tissue eQTLs, although disease relevant, cannot explain the majority of disease heritability.
228 purely bottom-up statistical learning alone cannot fully account for the ability to create abstract
229 om effect for a genetic relationship matrix, cannot fully account for the fine-scale geographical con
230 th two stimulus categories, but such designs cannot fully capture the limitations inherent in natural
231 rent methods for analyzing diploid Hi-C data cannot fully distinguish between homologous chromosomes.
232 groups also harbor ancestry from sources we cannot fully model with the available data, highlighting
235 reports, we find that protonation reactions cannot generally be classified as either charge- or fron
236 ay, as activating autophagy when the pathway cannot go to completion (e.g., when lysosomal degradatio
242 omyces cerevisiae strains in which MutLgamma cannot interact with PCNA present defects in forming cro
243 n of rnhA to encode an RNase HI variant that cannot interact with SSB but that maintains enzymatic ac
244 y care, and the current hepatology workforce cannot meet the demand of patients with liver disease na
246 gest that predictable molecular organization cannot normally be achieved using these embraces, which
247 stable in (CAG)n = even, but such situation cannot occur in (CAG)n = odd, where the hairpin is "frus
250 improve quality and access for patients who cannot, or choose not to, receive their care at high-vol
254 riables do not correlate which means that we cannot predict patient survival solely based on the init
256 S biosynthesis and that an HH103 rkpM mutant cannot produce KPS and displays an altered LPS structure
257 Similarly, an ept1Delta/Delta mutant, which cannot produce PE by the Kennedy pathway, exhibits decre
259 e mostly based on physical examinations that cannot provide information about the exact location of c
260 However, existing empirical methods often cannot provide key genetic and functional details requir
262 ommon and lethal syndrome in which the heart cannot pump blood to adequately meet bodily demands, res
263 However, we discovered that bursting alone cannot quantitatively recapitulate the formation of the
264 Here we show that static abiotic dissolution cannot rationalize this result, whereas two dynamic abio
266 ally reparable pores generated by LEEFT that cannot recover in the subsequent ozonation and the great
267 , the existing peak deconvolution algorithms cannot recover the accurate expression level of genes in
270 t electrophysiological or optical techniques cannot reliably perform simultaneous intracellular recor
274 lay in neuronal birth, suggesting that Ascl1 cannot rescue the loss of Neurog2 and that these proneur
275 orientations in the phospholipid bilayer but cannot resolve the actual distribution of molecules embe
279 which an organism is exposed, these sensors cannot reveal the presence and extent of internal tissue
280 ext of systemic LCMV or VV infection, but we cannot rule out the possibility that the generation of T
281 ed original science, conceptual replications cannot serve as the field's self-correction mechanism.
282 However, conventional patterning methods cannot simultaneously meet the stringent requirements of
285 regimes in which population structure alone cannot support coexistence, suggesting the need for othe
286 01D/S241D, a phosphorylation-mimicry mutant, cannot suppress VEGFA expression to support normal vascu
288 he spread of resistance, but small companies cannot survive on revenues that do not cover operational
289 enic genes to other organisms, and that they cannot survive to propagate in unintended environments,
293 data to ASD; however, this previous approach cannot take into account for prior biological knowledge.
294 alkylation with mesitylene, a reaction that cannot take place in the zeolite micropores, is observed
296 This indicates that some plankton species cannot track optimal temperatures on a global scale as a
297 nce to a near-scientific certainty that they cannot transfer their transgenic genes to other organism
299 ve analysis of alpha7 with its homologs that cannot trigger channel opening has not been made so far.
300 ltifactorial pathophysiological process that cannot yet be recapitulated in a single in vitro model.