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1 ay have an adaptive advantage over those who cannot.
2 hronize their movements in ways that novices cannot.
3  while changes in predator-prey interactions cannot.
4 emaining absorption surface of the intestine cannot absorb enough macronutrients, micronutrients, and
5 jacent motif (PAM) requirements, CRISPR/Cas9 cannot access many genetic loci.
6 GxE genome-wide are nascent and, as we show, cannot accommodate general environment variables, modest
7              However, their fixed dimensions cannot accommodate rapid tissue growth(4,5) and may impa
8  times for end-of-epidemic declarations that cannot accommodate these variations.
9                                   This model cannot account for interactions of edges with one anothe
10              Although photoevaporation rates cannot account for the mass loss required to reduce a Ju
11               Existing computational methods cannot accurately reconstruct activities of individual c
12 llows for rapid staining, but these sections cannot accurately represent three-dimensional structures
13 bserve that all the state-of-the-art methods cannot achieve an ideal accuracy for overlap detection (
14 but its diagnostic accuracy is limited as it cannot adequately distinguish between true tumor progres
15                The time to act is now and we cannot afford to ignore the new solutions that GM provid
16 dies, where optimal pre-analytical condition cannot always be guarantee.
17 putational cost, existing region-based tests cannot analyze hundreds of thousands of samples while ac
18 nic degeneracy or pseudodegeneracy, but they cannot be a priory fully excluded for any system.
19  Neoproterozoic Snowball Earth and therefore cannot be a product of glacial erosion.
20 ue to sp(2) carbon-conjugated frameworks and cannot be accessible by imine-linked frameworks, amorpho
21  3D perovskite AMX(3) structure because they cannot be accommodated in the cubo-octhedral cage (do no
22 ing the transition toward circularity, which cannot be achieved by technology improvements alone-the
23                       These attributes often cannot be achieved by traditional molecular sensors i.e.
24                                         Such cannot be achieved by utilizing capsid sequence data alo
25 x biological regulatory mechanisms when this cannot be achieved solely through experimental approache
26 luorescence imaging of kidney cancers, which cannot be achieved with hepatobiliary- and glomerular-cl
27 antagonizing platelet integrin alphaIIbbeta3 cannot be achieved without compromising hemostasis, thus
28 ing residues 1-4 are functional Rubiscos but cannot be activated.
29                                This question cannot be answered by simply recording from multiple bra
30                    Importantly, most methods cannot be applied to either GWAS/eQTL summary statistics
31  the fluorescent particles can diffuse, they cannot be applied to situations in which this region is
32 here liquid chromatography-MS-based analyses cannot be applied.
33 of choice when dealing with matrix data that cannot be arranged into a trilinear three-way array, tha
34 low abundances of amino acids in Tagish Lake cannot be ascribed to fluid chemistry.
35 also suggests that ATP and NAD(P)H balancing cannot be assessed in isolation from each other, or even
36  surgical intervention's impact on mortality cannot be assessed in this study, as it would need to be
37                           Treatment efficacy cannot be assessed with this measure during clinical tri
38  potential periprosthetic shoulder infection cannot be assumed.
39 tems also exhibit specific reactivities that cannot be attained with regular substrates.
40 ent anti-biofilm activity of Bald's eyesalve cannot be attributed to a single ingredient and requires
41 ress, however successful fragile site repair cannot be calculated using existing techniques.
42 Treg) during coculture assays, features that cannot be captured by using surrogate cell lines or anim
43    In humans, clinical manifestation of tics cannot be captured via functional imaging due to motion
44                    Organic liquids, however, cannot be charged effectively by existing methods due to
45 othalamic tract, and other deep brain nuclei cannot be clearly identified.
46        Partial flow recovery with forest age cannot be commonly expected, however, and forestation pr
47 , sIPV products from different manufacturers cannot be compared, and the relationship between antigen
48 AC has an essential and unique function that cannot be compensated by other HDAC complexes.
49  Residual confounding by comorbid conditions cannot be completely excluded.
50 liferation, and note that these observations cannot be conducted within previous continuum models of
51 suming and more often is only indicative and cannot be considered confirmative as it is susceptible t
52       Accordingly, patients with burn injury cannot be considered recovered when the wounds have heal
53 icates that the development of mental health cannot be considered without consideration of children i
54              The filaments inside the bundle cannot be continuously actuated, nor can they easily unb
55 that when population structure is recent, it cannot be corrected using principal components of common
56               Such posttreatment confounding cannot be dealt with using standard methods (e.g., gener
57 eans that a symbol must be taken as such and cannot be decomposed into signal and noise.
58  specific adverse effects of ROS1 inhibition cannot be deconvoluted from the toxicity profiles of the
59           This fact suggests that RFs of SDs cannot be defined as homogeneous sensory zone driven by
60  such as remdesivir and reconvalescent serum cannot be delivered orally(2,3), making them poorly suit
61 cancer screening, the number of cancers that cannot be detected with mammography is substantial, espe
62 ctions are difficult to analyze because they cannot be determined by comparing the energies of compet
63 pecies transmission and the drivers for this cannot be determined from this study.
64  harms of screening for cognitive impairment cannot be determined.
65 that the biodegradation performance in soils cannot be directly assessed by measuring the expression
66                   In contrast, PopZ and SpmX cannot be directly identified in CET.
67 hnical limitation of estimating g(m) , which cannot be directly measured, and (iv) how g(m) responds
68 le costs on society; however, their benefits cannot be directly observed and are currently understood
69 on structure and transcriptional states that cannot be discerned from bulk measurements, establishing
70 tributions from homologous antenna complexes cannot be disentangled.
71 a 1:1 protein-lipid complex, where the lipid cannot be displaced by detergent from the highly protect
72 toxin A gene (sea) causes food poisoning and cannot be distinguished from non-pathogenic strains by t
73 ble elements from which reliable conclusions cannot be drawn, and therefore has made the decision to
74 f cryptic lineages within the upwelling zone cannot be easily accounted for by environmental heteroge
75 e inherent property of a given material that cannot be easily changed at will.
76 probes are limited in scope, though, as they cannot be easily distinguished in biological environment
77 changes at local scale are often complex and cannot be easily generalized.
78                   Since SOC content of soils cannot be easily measured, a key barrier to implementing
79 ls based on their migratory characteristics, cannot be easily performed.
80   We show that the striped fibrillar pattern cannot be easily predicted from the interactions between
81 ression system or show unusual features that cannot be easily programmed in living organisms.
82 nate human senses, the complexity perception cannot be easily quantified.
83      This causes problems when the biosensor cannot be easily replaced (e.g., implanted electronics).
84 uence complexity (TTAGGG)n of telomeres that cannot be easily resolved through sequencing.
85    The reaction is truly three-component and cannot be effectively performed stepwise.
86                              Since phosphate cannot be efficiently removed by dialysis, the resulting
87 : 2.93, 1.79-4.79; confounding by indication cannot be excluded).
88                  Given a small effect on CHD cannot be excluded, further investigation with stronger
89     However, traditional chemical inhibitors cannot be experimentally applied with spatiotemporal pre
90 g learning and memory; however, this process cannot be explained by a simple linear trajectory of tra
91 ifts observed in several FLE conditions that cannot be explained by alternative (temporal) models of
92       The increase seen across birth cohorts cannot be explained by changes in occupation or levels o
93 duced iodine emissions from natural seawater cannot be explained by chemical losses of I(2) or hypoio
94 s a lower genotype-derived heritability that cannot be explained by inclusion of milder cases and a h
95 2) the dapagliflozin-induced increase in EGP cannot be explained by the increase in plasma glucagon o
96                      Importantly, the latter cannot be explained by theta power changes, head movemen
97 deep low-stability layer in the polar region cannot be explained by vertical convection in the middle
98 ovir toxicity in patients taking ART for HIV cannot be explained solely on the basis of off-target in
99 ral rearrangement in the process XS -> XS(-) cannot be explained using the values of the electron det
100                                 These values cannot be explained with classical models for optical ou
101 ysical properties which are averaged out and cannot be exploited in disordered systems.
102  differentiated for effective sensing, which cannot be fulfilled by common PDs with a broadband respo
103   As yet, this multi-length-scale complexity cannot be fully captured by atomistic simulations, and t
104 ted that annual phytoplankton biomass cycles cannot be fully understood from environmental properties
105 ctions and network architectures exists, but cannot be fully understood without attention to the envi
106 al profile was dependent on the cultivar and cannot be generalised.
107 mary pseudotumor cerebri, in which the cause cannot be identified (also known as idiopathic intracran
108 racteristics with mammalian enteric glia but cannot be identified by the expression of canonical glia
109 ss weak magnetic remanence (Fe(3) O(4) ), or cannot be implemented in nanofabrication schemes (NdFeB)
110 challenge for cells is that these objectives cannot be independently optimized, and maximizing one of
111 heir conditional informativeness for disease cannot be inferred from their accuracy in predicting reg
112 I antimicrobial susceptibility testing (AST) cannot be interpreted using recognized standards.
113 ti-spin nanoscale devices, because the field cannot be localized or screened.
114         Unfortunately, many control measures cannot be maintained indefinitely, and the results of ce
115                       The true population LD cannot be measured directly and instead can only be infe
116 xplain phenotypes of genetic diseases, which cannot be obtained by transcript information alone.
117 d variance, scores, and other results, which cannot be obtained in the conventional cross-validation.
118 urface response (i.e., heterogeneity), which cannot be obtained solely by an electrochemical means.
119 ss spectrometry for accurate diagnosis of MN cannot be overemphasized.
120 ods for SCD are time-consuming, complex, and cannot be performed at point-of-care (POC) and home sett
121 gh the generation of mice in which eIF2alpha cannot be phosphorylated specifically in Schwann cells.
122       Hydroxychloroquine exposure is low and cannot be predicted by other populations.
123  the success or failure of a given structure cannot be predicted by quality metrics such as resolutio
124              Since the pathway of resistance cannot be predicted, combination therapies may address t
125 the specific metal used by any family member cannot be predicted.
126 ks are not stabilized, and new origin firing cannot be prevented, leading to the accumulation of DNA
127 dels, we demonstrate that these observations cannot be produced by previously proposed horizontal ext
128 fore a full range of template concentrations cannot be quantified accurately with these methods alone
129 es, yet animals eventually reject tumors and cannot be raised at 37 degrees C.
130 hydrogels with a desirable network structure cannot be readily achieved using conventional polymeriza
131 g of complex genomic regulation in vivo that cannot be readily investigated through standard methodol
132 ow is well suited to biological samples that cannot be readily isotope labeled, including plants, mam
133 ents after ischaemic stroke, and thus S44819 cannot be recommended for stroke therapy.
134 days of storage to be used in a DMEK surgery cannot be recommended.
135 difficulties incorporating binding data, and cannot be reduced or connected to simpler forms.
136  those claiming that one's scientific impact cannot be reduced to a single number.
137  not ideal because often the null hypothesis cannot be rejected simply due to limited statistical pow
138 s of gasteroid forms are highly unlikely but cannot be rejected.
139               Second, because ADE of disease cannot be reliably predicted after either vaccination or
140 to inappropriate post-harvest processing and cannot be removed in the subsequent chocolate-manufactur
141 ng that this property is highly variable and cannot be represented by a single value based on the AO-
142 female lethality of DH6 is 100% dominant and cannot be repressed by maternal tetracycline.
143 c behavior observed in synaptic transmission cannot be reproduced in a standard kinetic model without
144 linical experiments are giving results which cannot be reproduced.
145             Ubiquitous pathological triggers cannot be responsible for the selective neuron loss.
146 sclose biological discoveries that otherwise cannot be revealed by existing approaches.
147 ls measured in the general population, risks cannot be ruled out due to the potential for population
148 ity of neuroinvasiveness of the virus, which cannot be ruled out given the expression of low levels o
149              Although unmeasured confounding cannot be ruled out, when analyzed by time periods, or a
150 uire field experts to create them, and often cannot be shared outside the lab due to medical regulati
151                   Thus, biodiversity changes cannot be solely viewed as a response to human influence
152 d injury at the cellular and molecular level cannot be studied in vivo.
153 ange and human response and argue that these cannot be successfully addressed without an understandin
154                     However, a full lockdown cannot be sustained for a prolonged period.
155 is do not occur on the Mexican Pacific coast cannot be sustained.
156 chitin into two aromatic NCCs that currently cannot be synthesized from chitin via any chemical proce
157 e access to the properties of compounds that cannot be synthesized in single-phase form, sparing cost
158 -50% or less in many cohorts, a good ranking cannot be taken to imply that the gene or disease at ran
159 own or inaccessible activity profiles and so cannot be targeted by such strategies.
160                              This assumption cannot be tested directly, but it can be falsified.
161 lly polar, it is heavily disordered and this cannot be the sole reason for the ferroelectricity.
162  replicate in these mosquitoes and therefore cannot be transmitted to people even in the unlikely eve
163 ntions to mitigate them even in patients who cannot be transplanted.
164 mena that can be surprisingly rich and often cannot be understood by studying only the individual con
165 r osmolarity measured with TearLab osmometer cannot be used as a key indicator of DED.
166 an quantify corneal elasticity ex vivo, they cannot be used clinically.
167 ality assumption are readily available, they cannot be used directly because the included studies hav
168 ltra as a single diagnostic test for TBM; it cannot be used to "rule out" TBM.
169                    Proliferation rates alone cannot be used to achieve cancer specificity.
170                        Consequently, D-dimer cannot be used to exclude DVT without an assessment of p
171 ber of core single nucleotide variants alone cannot be used to infer cross-transmission in M. abscess
172 al intensity, such as those for well plates, cannot be used to quantify signal from most of these dev
173 mice and all existing humanized mouse models cannot be used to test the efficacy of vaccines expressi
174 re inefficient because lower-quality samples cannot be used, and they assume individuals are identifi
175 tings where existing experimental strategies cannot be used.
176                    Coronary microcirculation cannot be visualized in vivo in humans, and functional i
177 nitive or reward-related impairments, yet it cannot be wholly related to one or the other process and
178 emperatures for growth and processing, which cannot be withstood by the substrate underneath.
179 g hyperactive MYC transcription factors that cannot bind JAZ repressors.
180 rupt editing in vitro, suggesting that PPR65 cannot bind modified bases due to differences in the str
181                            While L11 protein cannot bind to the GAC until the RNA has adopted its ter
182     We argue that statistical measures alone cannot capture all structural aspects of LCRs and recomm
183 method for analyzing rational process models cannot capture an important constraint on resource alloc
184 y are usually very successful but inherently cannot capture the quantum-optical nature of the process
185 ch is composed of a grating and line sensor, cannot capture the spectral behavior from noise to stabl
186 ture whereas traditional FSSs are static and cannot change their performance.
187 ovo emergence of resistance even though they cannot clear already-large resistant populations.
188                                     Legumain cannot cleave after glycosylated Asn residues, which ena
189            Bovine derived chymosin in rennet cannot coagulate camel milk (CAM).
190     When we face ambiguous images, the brain cannot commit to a single percept; instead, it switches
191                          We show that NLGN4Y cannot compensate for the functional deficits observed i
192 rly studies suggested that Fe(III) complexes cannot compete with Gd(III) complexes as T(1) MRI contra
193 y, AID(S38A/S38A)UNG(-/-) mouse B cells also cannot complete CSR or affinity maturation despite accum
194                         Although our results cannot conclude physical fitness is related to white mat
195 ks the ability to initiate transcription and cannot consistently transcribe through long DNA sequence
196                     Furthermore, this mutant cannot correct alterations in both Syt1 expression and t
197 otential value of refined tools of this sort cannot currently be made because such an assessment woul
198 ersistently even if its cortical contraction cannot deform a near-rigid ECM, but then the contraction
199 le sulfate to oxidize the sub-arc mantle and cannot deliver (34)S-enriched sulfur to produce the posi
200                               Cohort studies cannot determine causality, and current disease severity
201 unts in people's vaccine decision-making, it cannot determine whether different degrees of severity i
202                                      We also cannot determine whether observed changes in purchases a
203 tractant gradients between a source and sink cannot direct cells over such ranges.
204                These cohort-based approaches cannot directly identify individual pathogenic noncoding
205 us on prioritization of candidate genes, and cannot directly infer the specific functional effects of
206 hermore, we show that predictive information cannot distinguish between organisms that are adapted to
207 on about leukaemia biology and prognosis, it cannot distinguish which mutations occur in the same clo
208  its interactions, but most in vitro studies cannot duplicate the unique spatial arrangement of cMyBP
209 capturing a subset of cleansing effects, but cannot easily handle cleansing effects in non-moral, non
210 , required for NMR excitation and detection, cannot easily penetrate the battery casing due to the sk
211 bit structural and molecular alterations and cannot effectively compensate for fluid extravasation an
212                     Therefore, these methods cannot effectively correct all misalignments.
213 ficult because available therapeutic regimen cannot effectively kill and eliminate ERPC cells.
214 lysogenic), type I CRISPR-Cas immune systems cannot eliminate the phages from the bacterial populatio
215 rphological measurements of the root systems cannot entirely explain variations in citrate-enhanced u
216                                  Although we cannot exclude other differences, and in particular alte
217 iring more anti-VEGF injections; however, we cannot exclude that the RNFL thinning may be secondary t
218 g extends classical computing means that one cannot expect arbitrary simulations to be sped up by a q
219 vealed that carrier-mediated transport alone cannot explain the experimentally determined auxin distr
220 ulk tissue eQTLs, although disease relevant, cannot explain the majority of disease heritability.
221                     However, this hypothesis cannot explain the multi-Myr lag between the delta(13)C
222                        Two-population models cannot explain the results.
223 at belowground morphological diversity alone cannot explain this rate increase.
224                    Here, we show that TMC1/2 cannot form mechanotransduction channels in cochlear hai
225 l prefrontal cortex, but not in animals that cannot form new myelin.
226                            Consequently, one cannot formally examine whether hospitals that have poor
227 egeneration expected at genomic regions that cannot freely recombine.
228  purely bottom-up statistical learning alone cannot fully account for the ability to create abstract
229 om effect for a genetic relationship matrix, cannot fully account for the fine-scale geographical con
230 th two stimulus categories, but such designs cannot fully capture the limitations inherent in natural
231 rent methods for analyzing diploid Hi-C data cannot fully distinguish between homologous chromosomes.
232  groups also harbor ancestry from sources we cannot fully model with the available data, highlighting
233 in well myelinated mice in which glial cells cannot fully support axons metabolically.
234                          Hence, -10 elements cannot function in isolation.
235  reports, we find that protonation reactions cannot generally be classified as either charge- or fron
236 ay, as activating autophagy when the pathway cannot go to completion (e.g., when lysosomal degradatio
237                                           We cannot, however, evaluate the efficacy of treatments wit
238                                         GWAS cannot identify functional SNPs (fSNP) from disease-asso
239 vivo studies, may reduce the TTI further, it cannot increase it.
240 ho sees the responses to random inputs-still cannot infer responses to new inputs?
241 s the AID phosphorylation mutant, AID(S38A), cannot interact with APE1, a BER protein.
242 omyces cerevisiae strains in which MutLgamma cannot interact with PCNA present defects in forming cro
243 n of rnhA to encode an RNase HI variant that cannot interact with SSB but that maintains enzymatic ac
244 y care, and the current hepatology workforce cannot meet the demand of patients with liver disease na
245       Moreover, evidence suggests infections cannot neatly be separated into the dichotomy of droplet
246 gest that predictable molecular organization cannot normally be achieved using these embraces, which
247  stable in (CAG)n = even, but such situation cannot occur in (CAG)n = odd, where the hairpin is "frus
248                         Meanwhile, MT-SCCALR cannot only select relevant SNPs and imaging QTs for eac
249                               Thus, c-di-GMP cannot only stabilize domain interactions, but also enga
250  improve quality and access for patients who cannot, or choose not to, receive their care at high-vol
251 ETs are in an inactive conformation and thus cannot participate in further catalytic events.
252 mining motion in the environment, but humans cannot perform this task without error.
253 proliferative advantage, below which mutants cannot persist.
254 riables do not correlate which means that we cannot predict patient survival solely based on the init
255 substantial overpotential is applied, and it cannot produce H(2).
256 S biosynthesis and that an HH103 rkpM mutant cannot produce KPS and displays an altered LPS structure
257  Similarly, an ept1Delta/Delta mutant, which cannot produce PE by the Kennedy pathway, exhibits decre
258 means that the groups enter areas where they cannot profit from local knowledge.
259 e mostly based on physical examinations that cannot provide information about the exact location of c
260    However, existing empirical methods often cannot provide key genetic and functional details requir
261 oint-of-care analysis or home monitoring and cannot provide real-time readouts.
262 ommon and lethal syndrome in which the heart cannot pump blood to adequately meet bodily demands, res
263   However, we discovered that bursting alone cannot quantitatively recapitulate the formation of the
264 Here we show that static abiotic dissolution cannot rationalize this result, whereas two dynamic abio
265            Based on the present findings, we cannot recommend continuous intranasal oxytocin treatmen
266 ally reparable pores generated by LEEFT that cannot recover in the subsequent ozonation and the great
267 , the existing peak deconvolution algorithms cannot recover the accurate expression level of genes in
268                                   The result cannot reflect spurious selection of out-of-system areas
269                                   The tracer cannot reliably differentiate non-Alzheimer tauopathies
270 t electrophysiological or optical techniques cannot reliably perform simultaneous intracellular recor
271 imCells can be used as a safe agent (as they cannot replicate) for bacterial therapy.
272               While one-sided loop extrusion cannot reproduce these phenomena, variants can recapitul
273                         However, ectopic DPP cannot rescue the anterior fate formation, suggesting ad
274 lay in neuronal birth, suggesting that Ascl1 cannot rescue the loss of Neurog2 and that these proneur
275 orientations in the phospholipid bilayer but cannot resolve the actual distribution of molecules embe
276           Conventional analytical techniques cannot resolve the distribution of excipients and drugs
277                             Current theories cannot resolve this apparent contradiction.
278                                However, they cannot reveal key structural information, e.g., lectin's
279  which an organism is exposed, these sensors cannot reveal the presence and extent of internal tissue
280 ext of systemic LCMV or VV infection, but we cannot rule out the possibility that the generation of T
281 ed original science, conceptual replications cannot serve as the field's self-correction mechanism.
282     However, conventional patterning methods cannot simultaneously meet the stringent requirements of
283                      Large organic A cations cannot stabilize the 3D perovskite AMX(3) structure beca
284                 In the latter, an individual cannot stop using a drug despite major negative conseque
285  regimes in which population structure alone cannot support coexistence, suggesting the need for othe
286 01D/S241D, a phosphorylation-mimicry mutant, cannot suppress VEGFA expression to support normal vascu
287 han 3.5-6%; and iv) the total sterol content cannot surpass 2400 mg/kg.
288 he spread of resistance, but small companies cannot survive on revenues that do not cover operational
289 enic genes to other organisms, and that they cannot survive to propagate in unintended environments,
290            These include compounds that pups cannot synthesise themselves, such as pyridoxine/vitamin
291                     Because Nitrobacter spp. cannot synthesize cobalamin, we postulate that they acqu
292                               E. chaffeensis cannot synthesize phosphatidylcholine or cholesterol but
293 data to ASD; however, this previous approach cannot take into account for prior biological knowledge.
294  alkylation with mesitylene, a reaction that cannot take place in the zeolite micropores, is observed
295 materials, such as conventional metal films, cannot tolerate.
296    This indicates that some plankton species cannot track optimal temperatures on a global scale as a
297 nce to a near-scientific certainty that they cannot transfer their transgenic genes to other organism
298  stranded (ds) complex that does not fit and cannot traverse this nanopore.
299 ve analysis of alpha7 with its homologs that cannot trigger channel opening has not been made so far.
300 ltifactorial pathophysiological process that cannot yet be recapitulated in a single in vitro model.

 
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