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1 e latter with an NCO-alkyl residue (imide or carbamate).
2 mers were synthesized (N-aryl, N-alkyl and N-carbamate).
3 er the conjugates previously connected via a carbamate.
4 reaction of glycosylamines with fluorescent carbamate.
5 amines into well-ordered chains of ammonium carbamate.
6 ddition of CO2 since it cannot form a stable carbamate.
7 rting ADP and carbamoyl phosphate to ATP and carbamate.
8 electrophiles such as sulfonamide, urea, and carbamate.
9 ed by FTIR and tentatively assigned as a PTE carbamate.
10 pyrethroids, and 1.5 (95% CI: 0.5, 4.8) for carbamates.
11 to convert all primary amines to less basic carbamates.
12 reaction of N-arylhydroxylamines with diene carbamates.
13 )alkylboronates to enantioenriched lithiated carbamates.
14 HAS permit formation of chemically distinct carbamates.
15 urrently accomplished with (sulfon)amides or carbamates.
16 ciations with, respectively, pyrethroids and carbamates.
17 n also be applied toward the fluorination of carbamates.
18 ed secondary dialkyl TIB esters, but not the carbamates.
19 aza-Heck cyclizations of alkenyl N-(tosyloxy)carbamates.
20 nt role in natural remediation mechanisms of carbamates.
21 ngement reactions of the corresponding allyl carbamates.
22 f alpha-lithiated haloalkanes, epoxides, and carbamates.
23 imidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate 1 (PDDC), the first nSMase2 inhibitor that pos
24 properties were determined for the biphenyl carbamates 13m and 13n, neutral antagonism was observed
25 arbamates 5-7 (Scheme 2 ) and meta-protected carbamates 14, 15, and 20 (Schemes 5 and 7 ) by s-BuLi/(
26 luorobenzoyllysineoxypentanedioic acid (OPA) carbamate [(18)F]23 and 4-iodo-2-[(18)F]fluorobenzoyllys
27 and 4-iodo-2-[(18)F]fluorobenzoyllysine OPA carbamate [(18)F]24 in particular exhibited high target-
28 rnal standard instead of less similar propyl carbamate; (2) extraction by diethyl ether instead of mo
30 r functionalized tertiary N,N-dialkyl aryl O-carbamates 5-7 (Scheme 2 ) and meta-protected carbamates
31 or quinuclidine unit attached to a biphenyl carbamate, 5-fluoro substitution was responsible for M(3
34 alkyl electrophile to generate a substituted carbamate, a process that has not been achieved effectiv
35 y of functional groups, such as an olefin, a carbamate, a thiophene, and a pyridine, and it has been
36 2,3-substituted-phenyl)piperazine-1-yl]alkyl]carbamates, a novel class of molecules that had shown pr
37 Two chemical probes, Azido Benzyl ferrocene carbamate (ABFC) and N-alkyl Azido Benzyl ferrocene carb
38 ligand paradigm was applied to the design of carbamates able to simultaneously target the recently pr
39 te (AQC), aminophenyl- N-hydroxysuccinimidyl carbamate (AC), and 3-aminopyridyl- N-hydroxysuccinimidy
44 les bearing both a lipophilic P2 isoindoline carbamate and a P1/P1' acylsulfonamide/acylsulfamide car
45 ne (generating mixtures of the corresponding carbamate and carbamic acid) with a well-established Mn
48 ne spacers (2 to 10 methylene groups between carbamate and heterocycle) in the carbamate residue was
54 nitrogen nucleophiles such as sulphonamides, carbamates and amides have been shown to be appropriate
56 l adsorbs CO2 via formation of both ammonium carbamates and carbamic acid pairs, the latter of which
57 The ortho-directed lithiation of aromatic carbamates and carbonates causes a migration of the subs
58 ates (e.g., pivalates, acetates, etc.), aryl carbamates and carbonates, to aryl ethers (anisoles, dia
59 ross-coupling reaction of stereodefined enol carbamates and Grignard reagents to yield tri- and tetra
61 is strategy for the preparation of energetic carbamates and nitrocarbamates starting from readily ava
64 to the formation of the corresponding amine carbamates and protonated amines that were identified by
67 mines, amides, isocyanates, isothiocyanates, carbamates and thiocarbamates with OH radicals within a
69 s based on labeled carboxylic acids, amides, carbamates and ureas now account for a substantial numbe
72 -ides to tert-butyl (S)-(3-oxopent-4-yn-2-yl)carbamate, and their structures were determined by NMR,
74 dissolving-metal cleavage of hindered phenyl carbamates, and an aminoiodocyclization to form the pyrr
75 o selectively access a broad range of ureas, carbamates, and heterocycles via ruthenium-based pincer
77 , and imides (i.e., benzamides, tosylamides, carbamates, and phthalimide) to form the corresponding N
79 chemical methodologies for the synthesis of carbamates, and recent applications of carbamates in dru
81 of N-(2-(2-phenylthiazol-4-yl)ethyl)amides, carbamates, and ureas, which rapidly, selectively, and p
82 regioselective metalation of ester-, amide-, carbamate-, and carbonate-substituted 2-phenyl-2-oxazoli
83 ative conjugate addition of a thiourea-bound carbamate anion to a vinyl phosphonium ion resulting fro
86 e with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) for the determination of amino acids was
87 were 6-aminoquinolyl- N-hydroxysuccinimidyl carbamate (AQC), aminophenyl- N-hydroxysuccinimidyl carb
88 N-Terminal Ser residues containing an Fmoc carbamate are converted into 2-(9'-fluorenylmethyloxy)-2
93 d, mediated by PhIO in iPrOH, using ammonium carbamate as the NH source, and in the presence of 1 equ
94 ibrium during the 4 h study period, suggests carbamates as alternative scaffolds for mitigating dose
95 alizations illustrate the versatility of the carbamates as precursors to enantioenriched small molecu
96 ed variants of proline and the corresponding carbamate, as well as the four proline residues of an Sr
97 , carboxylic acids, amides, isocyanates, and carbamates, as well as tetrahydrofuran and gamma-butyrol
99 ectivity over hAChE was synthesized based on carbamates attached to tetrahydroquinazoline scaffolds w
102 d with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate before analysis using liquid chromatography el
104 methrin) insecticide in the first year and a carbamate (bendiocarb) insecticide in the two subsequent
105 primary ureas, secondary/tertiary ureas, O/S-carbamates, benzoyl ureas, amides, and N-formyls, exploi
106 otoxins, whilst the second encompasses ethyl carbamate, biogenic amines, sulfur dioxide and proteins
109 unctionalized 'ABA' triblock copolymers with carbamate block junction, which can form hydrogen-bonds.
110 Herein we demonstrate that N-acyl-tert-butyl-carbamates (Boc) and N-acyl-tosylamides (Ts), two classe
112 anes, sugar moieties, azetidines, tert-butyl carbamates (Boc-group), cyclobutanes, and spirocycles.
113 and hydrolysis, whereas, importantly, the NB carbamate bond had superior light responsiveness and res
114 elatively quickly from the oil depot and its carbamate bond was too stable to be used as a prodrug.
115 primary and secondary amines via an amide or carbamate bond; however, the ability to employ tertiary-
116 dly release curcumin in vitro via degradable carbamate bonds, and retain in vitro bioactivity against
117 ly in the absence of a catalyst; the product carbamates can serve as useful intermediates in organic
118 th EPR and UV-vis spectroscopy indicate that carbamates can undergo direct reactions with various rad
121 ns with the carbamate groups of the ammonium carbamate chains formed upon CO(2) adsorption, thereby i
122 o the formation of carbamic acid or ammonium carbamate chains that are stabilized by hydrogen bonding
124 ambda(6),2-benzothiazol-2- yl)methyl]benzoyl}carbamate CU-CPD103 (103), as a potent inhibitor using a
125 The reaction sequence involves a one-pot carbamate deprotection/imine formation/aerobic oxidation
128 fied to ~0.58 mol, with ~0.15 mol in form of carbamate dianions and ~0.43 mol in form of carbamic aci
129 o-Diels-Alder reaction of nitrosoarenes with carbamate-dienes afforded cis-3,6-disubstituted dihydro-
130 s the first example of an apparent amide and carbamate directing effect in metal-mediated reductive c
135 emonstrated that the use of nonracemic allyl carbamates enables the synthesis of enantioenriched benz
137 methylenedioxy, carbonate, cyclic carbonate, carbamate esters, and esters containing active transport
139 d cascade transformation involving a primary carbamate, ethyl glyoxylate, and various types of nucleo
142 d kinetic capture-and-release tests show the carbamate formation rate is fast enough to capture carbo
143 urther synthetic manipulations involving the carbamate formation, lactone reduction and cyclization,
145 tethered aminohydroxylation of a homoallylic carbamate function and a Petasis Borono-Mannich addition
146 we demonstrate that neuroprotective aromatic carbamates function to increase the Bcl-2/Bax ratio to a
147 rimary and secondary amines to less reactive carbamate functional groups, indicated that primary and
149 udies in pancreatic cancer cells showed that carbamate functionalization of the 4-amino group of gemc
150 compounds (formaldehyde, acetaldehyde, ethyl carbamate, furan, furfural and acrolein) found in wines.
151 deoxy-D-galactopyranosylidene)amino N-phenyl carbamate (GalPUGNAc), N-acetyl-D-glucosamine-thiazoline
152 ition to alkenes, and cleavage of the methyl carbamate gives the free aminocyclopropanes as their HI
156 rough hydrogen-bonding interactions with the carbamate groups of the ammonium carbamate chains formed
157 cular, hydrogen-bonding interactions through carbamate groups were found to be especially useful at d
160 sters) and secondary dialkyl N,N-diisopropyl carbamates have been reported to be resistant to deproto
161 ubstituents were used to control the rate of carbamate hydrolysis and the resulting protein release.
163 chemical groups: derivatives of (i) N-(tosyl)carbamate, (ii) p-toluenesulfonamide (PTSA), (iii) 4,4'-
164 ensation of the remaining ketone with methyl carbamate in the presence of acid initiated the programm
171 ibes an enantioselective synthesis of cyclic carbamates in which carbon dioxide engages an unsaturate
172 maticity of aromatic repeating units in poly(carbamates) increase the overall depolymerization rate.
173 get site loci (e.g. the Ace-1 target site of carbamate insecticides) or detoxification genes has been
175 mation of a putative alpha-chloro pyridinium carbamate intermediate, which appeared to readily underg
176 he tetrahydroquinazoline scaffold guides the carbamate into a close position to the active site.
177 transform di- and trisubstituted homoallylic carbamates into [4.1.0]-carbamate-tethered aziridines in
178 und n-alkylammonium oleate, phosphonate, and carbamate ion pairs that bind with greater affinity than
179 3 T) (13)C{(1)H} cross-polarization MAS NMR, carbamate is confirmed through splitting of the (13)C re
180 ecies that is either bicarbonate or a second carbamate is evident from bimodal T2 decay times of the
181 ecies in the near-surface region, while only carbamate is formed in the bulk, to differences in solva
182 a ring-closing metathesis reaction of allyl carbamates is presented as a method for the preparation
183 The epoxides, but not their urea, amide, or carbamate isosteres, impaired ATP production, enhanced c
185 that is substituted with a methylene-linked carbamate, leading to a 1,4-elimination of the carbamate
186 ochemical substrate leucine-benzyl ferrocene carbamate (Leu-FC) for selective profiling of LAP activi
187 ilic addition of free hydroxyl groups to the carbamate linkages and exhibits an Arrhenius activation
188 inating, electron-withdrawing benzyl alcohol-carbamate linker offers a probe having selective, sensit
190 elieve that tethering proteins by degradable carbamate linkers is a promising strategy to control the
193 action of N-allylated N-aryl or N-heteroaryl carbamates, may be useful intermediates for the rapid pr
195 nderlying mechanism, we have identified that carbamate-modified 3-fluoro sialic acid inhibitors are m
198 ng aziridinium intermediates with a tethered carbamate moiety) to give oxazolidin-2-ones was initiall
199 substituents located ortho or meta to the O-carbamate moiety, and O-carbamate N-substituents was inv
202 aterials such as hydroxamic acids, N-hydroxy carbamates, N-hydroxyureas, nitrile oxides, and 1,2,4-ox
203 te (ABFC) and N-alkyl Azido Benzyl ferrocene carbamate (NABFC) composed of azide trigger group were d
204 ate an array of functional groups, including carbamate NH, halogen, nitrile, olefin, ketone, and este
205 port, we address the challenge of coupling a carbamate nucleophile with an unactivated secondary alky
206 allenyl and propargyl esters with N-methoxy carbamate nucleophiles to yield alpha,beta-unsaturated g
207 and two quinuclidinium-substituted biphenyl carbamates OFH243 (13n), OFH244 (13m), OFH3911 (14n), an
208 enantioenriched primary/secondary lithiated carbamates or benzoates to give 1,3-bis(boronic esters),
210 members of all 4 major classes (pyrethroids, carbamates, organochlorines, and organophosphates) of pu
211 cide classes (chloroacetanilides, triazines, carbamates organophosphates) and two pesticide types (he
213 lectrostatic surface potential of a carbonyl/carbamate oxygen atom present in most KCNQ activators.
214 application of a previously disclosed cyclic carbamate P1 linker which provided improved oral bioavai
216 e, synthetic pyrethroid, organophosphate and carbamate pesticide residues in fruit juices using ultra
217 common organophosphorus, organochlorine and carbamate pesticides by 30-70% on tomato, rice, tea, bro
224 age was attained by the glycosylation of 2-N-carbamate-protected alpha-GlcN-lactol with N-phenyl-trif
225 lladium-catalyzed ortho-arylation of diethyl carbamate-protected estrone and estriol with aryl iodide
226 des, dipeptides, and tripeptides whereas its carbamate-protected form adopts trans-conformation.
227 rmer specificity of delta-azaproline and its carbamate-protected form in linear and cyclic peptides w
228 sh studies with allyl, propargyl, and benzyl carbamate-protected rhodamines confirmed N-Poc as the mo
230 yleneimides with easily removable N,N-di-Boc-carbamate protecting groups, allowing for a flexible yni
233 demonstrated, a rearrangement of (S,Z)-allyl carbamates provides (S)-teriary allylamines, whereas the
235 2-deoxy-D-glucopyranosylidene)amino N-phenyl carbamate (PUGNAc), O-(2-acetamido-2-deoxy-D-galactopyra
236 urotoxic pesticide groups (organophosphates, carbamates, pyrethroids, neonicotinoids, and manganese f
237 A variety of N-(1-methoxyalkyl)amides or carbamates react readily with sodium aryl sulfinates in
238 abeled with this reagent comprised of an NHS-carbamate reactive group, a quinoline fluorophore, and a
239 ve, we present properties and stabilities of carbamates, reagents and chemical methodologies for the
240 ps between carbamate and heterocycle) in the carbamate residue was synthesized and characterized in v
241 d method was optimized for the extraction of carbamate residues from a wide variety of fresh herbal p
246 o-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate (RL648_81), a new KCNQ2/3-specific activator t
247 e chemisorption reaction outcomes, including carbamate (RnNCOO(-)), carbamic acid (RnNCOOH), and bica
249 the CO2 carrier species, much the same as a carbamate serves as the CO2 carrier for amine-based capt
255 s use of alpha-lithio vinyl bromide or vinyl carbamate species, for which application to Zweifel-type
256 oposed mechanism involves protonation of the carbamate species, nucleophilic attack of the carbamic a
257 (-)-sparteine pair versus N,N-dialkyl aryl O-carbamate starting materials, temperature, solvents, ele
259 te terminal iron carbynes possessing an aryl carbamate substituent owing to the direct attachment of
260 ighly effective Diels-Alder reaction using a carbamate-substituted siloxy diene accompanied by a spon
263 reaction of the melampomagnolide-B-triazole carbamate synthon 6 with various terminal diamino- and d
264 stituted homoallylic carbamates into [4.1.0]-carbamate-tethered aziridines in good yields and with ee
265 ile bonds (i.e., ester, amide, carbonate, or carbamate) that served as labile crosslinks within step-
266 ure was observed including carbamic acid and carbamate, the former disappearing upon evacuation of th
269 The exposure to furan, acrolein and ethyl carbamate through wine consumption may pose risks to con
270 is the activation of a bicyclic iminoglycal carbamate to generate a highly reactive acyliminium cati
271 as electrochemically modified using ammonium carbamate to make it suitable for sensing free chlorine
272 zed enantioselective Markovnikov addition of carbamates to allylic alcohols for the construction of a
275 sticide classes, including organophosphates, carbamates, triazoles and pyrethroids from fruits and ve
278 lti-dose intraperitoneal injections of ethyl carbamate (urethane, 1 g/kg body weight) were establishe
283 rbents that uptake CO2 primarily as ammonium carbamates, we observe using solid state NMR that the ma
285 phophates, organochlorines, pyrethroids, and carbamates were aggregated within 1.25-km, 1.5-km, and 1
289 of reaction products also shifts to ammonium carbamate when water vapor is present; a new finding tha
290 The CO2 adduct of 1,2-azaborine is a cyclic carbamate which undergoes photocleavage, thus resulting
294 available olefins to internal vicinal fluoro carbamates with high regioselectivity (N vs F), many of
296 when applied to hindered systems (secondary carbamates with tBu-boronic esters) for the construction
297 constants for the formation of carbamic acid/carbamates with the protonation constant of the amine is
299 n achieve the coupling of a range of primary carbamates with unactivated secondary alkyl bromides at
300 opy, CO2 is found to be bound in the bulk as carbamate (with nominally 0.5 mol of CO2 bound per 1 mol