ライフサイエンスコーパス: carbamylate

1 iduals with CKD stages 2-4, higher levels of carbamylated albumin (a marker of protein carbamylation

2 gression to ESKD, we measured baseline serum carbamylated albumin (C-Alb) in 3111 patients with CKD s

3 We previously documented that carbamylated albumin had reduced cubilin binding, but th

4 e-specific multireactivity to citrullinated, carbamylated and acetylated epitopes.

5 ld type enzyme, the side chain of Lys-169 is carbamylated and also acts as a bridge between the two d

6 a identified 16 of the 21 lysine residues as carbamylated and suggested that the majority of apoA-I c

7 Recently, a new set of antibodies, anti-carbamylated (anti-CarP) antibodies, have been identifie

8 toplasmic loop, including Lys125, are indeed carbamylated by CO(2).

9 proteinase, we found a significant level of carbamylated cysteines.

10 s of "binary prodrugs" called carbaphens,(1) carbamylated derivatives on one or both of the aromatic

11 For example, carbamylated Epo (CEpo) does not stimulate erythropoiesi

12 Carbamylated erythropoietin (CEPO) is a novel neuroprote

13 Carbamylated erythropoietin (CEPO) lacks both erythropoi

14 Carbamylated erythropoietin (CEPO), a well characterized

15 a) calculations on the enzyme with Lys129 in carbamylated form predicts trends similar to those of th

16 LC/UVPD-MS of a carbamylated H. salinarum digest resulted in 45% more id

17 Rubisco was highly activated (carbamylated) in both light and dark, most likely reflec

18 lglyoxal labeling and Western blot to detect carbamylated integrin alpha (IIb) beta (3) (a receptor r

19 This study sought to determine whether carbamylated LDL (cLDL) exerts prothrombotic effects in

20 Carbamylated LDL (cLDL) is a potential atherogenic facto

21 nded by His-246, His-272, one oxygen atom of carbamylated Lys-217, and a water molecule at partial oc

22 ter in which two nickel atoms are bridged by carbamylated Lys217.

23 the active site until after formation of the carbamylated lysine metallocenter ligand.

24 ontaining enzyme, the bridging ligands are a carbamylated lysine residue (Lys 169) and a hydroxide.

25 active site with the metal ions bridged by a carbamylated lysine residue.

26 kel active site with the metals bridged by a carbamylated lysine residue.

27 hway leads to nearly uniform distribution of carbamylated lysine residues along the apoA-I polypeptid

28 h an active site cobalt ion coordinated by a carbamylated lysine, except in the oxaloacetate complex

29 he aim of this study with tablets containing carbamylated monomeric house dust mite allergoids was to

30 amate acts as a carboxyl acceptor, forming a carbamylated oxamate product and thereby accelerating th

31 We have previously shown that carbamylated PAF-induced repolarization abnormalities re

32 We identified the carbamylated peptides containing catalytic serine (Ser(1

33 ver, pathophysiologically relevant levels of carbamylated protein either incubated with cultured huma

34 generation following exposure to aerosolized carbamylated protein, but no changes in other asthma-rel

35 a reactive species in equilibrium with urea, carbamylates protein lysine residues to form epsilon-car

36 mediates protein carbamylation to form anti-carbamylated proteins (anti-CarP), perpetuating RA progr

37 urrence of autoantibodies, particularly anti-carbamylated proteins (anti-CarP).

38 It has been shown that carbamylated proteins increase in plasma and tissues dur

39 ularly directed against nuclear antigens and carbamylated proteins, emerging 10-15 days after the ons

40 lifespan and leads to tissue accumulation of carbamylated proteins.

41 In contrast, carbamylated rhEPO, a heteromeric receptor-specific liga

42 istent with experimental evidence that it is carbamylated, since an unprotonated amine group is avail

43 The chimeric enzyme had 11 +/- 1% fewer carbamylated sites and a 11 +/- 1% lower carboxylase act

44 decrease in basicity enhanced the binding of carbamylated sulfopeptides to WAX resin relative to nons