ライフサイエンスコーパス: carbohydrate structure

1 AMTS13 through steric hindrance by the bulky carbohydrate structure.

2 ion sites is occupied by a high mannose-type carbohydrate structure.

3 c compounds either mimicking or masking this carbohydrate structure.

4 these proteins were altered by the different carbohydrate structures.

5 licit immune responses that cross-react with carbohydrate structures.

6 f galectin-3 to mucins depends on peripheral carbohydrate structures.

7 S-C, which produces mucin lacking peripheral carbohydrate structures.

8 on specific alterations in mucin-associated carbohydrate structures.

9 used to validate and/or further characterize carbohydrate structures.

10 ups and are readily transformed into diverse carbohydrate structures.

11 parameters is crucial for the elucidation of carbohydrate structures.

12 ifficulty of chemically synthesizing complex carbohydrate structures.

13 densely covered with highly branched complex carbohydrate structures.

14 Ps containing more high-mannose than complex carbohydrate structures.

15 tivity with some cross-reactivity to related carbohydrate structures.

16 same core amino acid sequence but different carbohydrate structures.

17 linkage in the expression of the two surface carbohydrate structures.

18 90, suggesting that these epitopes contained carbohydrate structures.

19 uch as CD34 and podocalyxin present sulfated carbohydrate structures (6-sulfated sialyl Lewis x or 6-

20 Glycans are repeating carbohydrate structures added as post-translational modi

21 olecule and may shed light on how changes in carbohydrate structure affect protein conformation.

22 that shed light on the relationship between carbohydrate structure and anticancer activity.

23 drate receptors, where the idiosyncrasies of carbohydrate structure and binding are increasingly cons

24 method has broad application for determining carbohydrate structure and conformation and to the study

25 s a new and powerful tool for characterizing carbohydrate structure and conformational dynamics in so

26 ing: Specific mutations affected the precise carbohydrate structure and folding of the HA trimer.

27 polysaccharides are essential to understand carbohydrate structure and function.

28 ase gene expression and enzyme activity with carbohydrate structure and function.

29 o better understand the relationship between carbohydrate structure and the stability of cholinestera

30 a role for the charge carrier as a probe of carbohydrate structure and thus have significant implica

31 se structures expand the complexity of mucin carbohydrate structure and thus the functional potential

32 cated both by the vast diversity of possible carbohydrate structures and by their dynamic nature.

33 the tremendous variation inherent in natural carbohydrate structures and their multiple biological fu

34 between expression of these two cell surface carbohydrate structures and their relative contribution

35 s show that: 1) the activity is specific for carbohydrate structure, and 2) the proliferative respons

36 tter equalizes the sensitivities for diverse carbohydrate structures, and has the potential to remove

37 ses because of the observation that specific carbohydrate structures appear in specific spatial and t

38 Carbohydrate structures are modified and degraded in the

39 in 1 significantly reduced the addition of a carbohydrate structure at this site.

40 highest activity toward GalNAcbeta1-4GlcNAc carbohydrate structures at the non-reducing termini of o

41 IgG is a glycoprotein with an N-linked carbohydrate structure attached to the CH2 domain of eac

42 idues 1-49 of the activation peptide or with carbohydrate structures attached to these residues.

43 Here, we examine a variety of protonated carbohydrate structures by gas-phase hydrogen/deuterium

44 As a reservoir of complex carbohydrate structures called glycans, it plays critica

45 The array of carbohydrate structures carried on lipopolysaccharides c

46 of TN-R modification with distinct sulfated carbohydrate structures changes dramatically over the co

47 The complex carbohydrate structures decorating human proteins and li

48 rature range, the separation selectivity was carbohydrate structure dependent.

49 hope to inspire more researchers to consider carbohydrate structure, diversity, and binding as attrac

50 aliquots containing low picomole amounts of carbohydrate structures either enzymatically released fr

51 n arrays as tools for the elucidation of the carbohydrate structures expressed on cell surfaces.

52 monstrate a means for identifying artificial carbohydrate structures for targeted bacterial manipulat

53 gest novel strategies, based on the relevant carbohydrate structures, for promoting or inhibiting the

54 e majority of these antibodies recognize the carbohydrate structure Gal(alphal,3)Gal (gal epitope) pr

55 mate antibodies is a terminal galalpha1-3gal carbohydrate structure (gal antigen) present on glycolip

56 ind to terminal galactose alpha1,3-galactose carbohydrate structures (Gal) are present in humans and

57 The improved Carbohydrate Structure Generalization Scheme has been de

58 The intrinsic complexity of carbohydrate structures has hampered access to pure glyc

59 in the future make it possible to elucidate carbohydrate structure in great detail, thereby forming

60 The addition of a carbohydrate structure in the N-terminal domain of PEN-2

61 was 2.1 nm, and is consistent with extended carbohydrate structures in CEA.

62 7 but not IL-1beta, highlighting the role of carbohydrate structures in influencing cytokine response

63 atment type and WLZ response, and quantified carbohydrate structures in MDCF-2 and faeces.

64 Carbohydrate structures in the mesopelagic North Pacific

65 hose in MDCF-2, and (2) the levels of faecal carbohydrate structures in the trial participants.

66 pecies-specific and individual variations in carbohydrate structures, including histo-blood group oli

67 This has been validated for several diverse carbohydrate structures, including series of malto- and

68 Several studies have proposed certain carbohydrate structures, including sLex and related stru

69 entin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and gl

70 This lectin binds to high mannose carbohydrate structures, including those found on viruse

71 However, glycomics lags a step behind: carbohydrate structures involve numerous levels of isome

72 Expression of this unique sulfated carbohydrate structure is also temporally regulated, inc

73 carbohydrate specificity toward the O-linked carbohydrate structure known as Thomsen-Friedenreich ant

74 HuNV attaches to cell surface carbohydrate structures known as histo-blood group antig

75 ly with high mannose and fucosylated neutral carbohydrate structures, langerin has the ability to bin

76 ymes indicate that the microheterogeneity in carbohydrate structure may be responsible, in part, for

77 fect Gram-positive bacteria target cell wall carbohydrate structures, molecular mechanisms that confe

78 er hardware have made it possible to unravel carbohydrate structure more efficiently.

79 The heterogeneity of carbohydrate structures must represent the accessibility

80 as Lex, and clone 23 also binds the backbone carbohydrate structure nLacCer.

81 Disruption of the extensive carbohydrate structure normally present on alpha-dystrog

82 The membrane-distal repeated carbohydrate structure of LPS, the O antigen, can preven

83 trating the essential role of preserving the carbohydrate structure of mannan.

84 The carbohydrate structures of beta1-LAP are not required fo

85 To study the role of the carbohydrate structures of beta1-LAP in its biological f

86 ding to or interacting with the aromatic and carbohydrate structures of its uronic acid ester substra

87 ties, many of which are linked with specific carbohydrate structures of MFGM glycoconjugates.

88 Accumulating evidence is elucidating surface carbohydrate structures of symbiotic bacteria that drive

89 The carbohydrate structures of the Fv glycans and their impa

90 in bacterial GEs, interact with aromatic and carbohydrate structures of these substrates in the enzym

91 rence of type 1-piliated Escherichia coli to carbohydrate structures of vaginal mucosa plays a major

92 To investigate the effect of carbohydrate structure on Ab function, we have now expre

93 -react with highly similar or even identical carbohydrate structures on a variety of different natura

94 lar ligands, the function(s) of more generic carbohydrate structures on alpha-dystroglycan remain unc

95 The astounding number and complexity of carbohydrate structures on cell surfaces added support t

96 t from small molecules capable of perturbing carbohydrate structures on cells.

97 pattern recognition receptors that recognize carbohydrate structures on endogenous molecules and path

98 However, the subsets of carbohydrate structures on GPIbalpha recognized by the b

99 high-affinity binding to distinct sialylated carbohydrate structures on human platelets and salivary

100 ntibodies and their relationships to similar carbohydrate structures on infectious organisms, particu

101 the innate immune system showing binding to carbohydrate structures on microorganisms in a calcium-d

102 Sialylated carbohydrate structures on mucin play a role in adhesive

103 pattern recognition receptors that recognize carbohydrate structures on pathogens and self-Ags often

104 e C-type lectins that recognize cell surface carbohydrate structures on pathogens, and trigger killin

105 es use surface lectins to bind to sialylated carbohydrate structures on porcine endothelium, and indi

106 Hi microarrays for exploring the presence of carbohydrate structures on the bacterial surface.

107 fied by a diverse and abundant repertoire of carbohydrate structures on the cell surface, which is kn

108 ion dimerized, providing clear evidence that carbohydrate structures on the extracellular domain do n

109 human gastric epithelium, and its mimicry by carbohydrate structures on the surface of H. pylori may

110 hyaluronic acid on DCs and removal of these carbohydrate structures partially abrogated LC-DC cluste

111 apid and unambiguous distinction of isomeric carbohydrate structures persists as a tremendous analyti

112 Carbohydrate structures play important roles in many bio

113 y a mycobacterial phospholipid antigen whose carbohydrate structure precisely corresponds to mammalia

114 Computational approaches can aid in carbohydrate structure prediction, structure determinati

115 duced nonspecific binding due to the missing carbohydrate structure, presents an innovative matrix fo

116 Assembly of discrete carbohydrate structures requires the coordinated activit

117 ts that they may express a novel, sialylated carbohydrate structure(s) that binds to E-selectin.

118 fication of the cyclopentyl chelate complex [carbohydrate structure-see text] as the catalyst resting

119 f the palladium cyclopentyl chelate complex [carbohydrate structure-see text] in 26% yield as a appro

120 ensitive, providing additional evidence that carbohydrate structures shield important neutralization

121 ascular mucin-type glycoproteins bearing the carbohydrate structure sialyl-Lewisx.

122 cells, that recognizes the terminal sulfated carbohydrate structure SO4-4-GalNAcbeta1,4GlcNAcbeta1,2M

123 n response to desialylated cancer-associated carbohydrate structures such as Thomsen-Friedenreich (TF

124 ess the MECA-79 epitope, an unusual sulfated carbohydrate structure that belongs to an important clas

125 One carbohydrate structure that is likely to be important in

126 hey are mediated in large part by the ABO(H) carbohydrate structures that are carried on both the N-

127 Carbohydrate structures that contribute to protecting fr

128 We identified carbohydrate structures that correlated with binding by

129 of human cancers, generating cancer-specific carbohydrate structures that could be used as biomarkers

130 jejuni possesses an extensive repertoire of carbohydrate structures that decorate both protein and n

131 umber of bacteria have been found to express carbohydrate structures that mimic host glycans.

132 l capsular polysaccharides (CPS) are complex carbohydrate structures that play a role in the overall

133 This carbohydrate structure (the alpha-galactosyl epitope) is

134 Despite the diversity of carbohydrate structures, the core beta-D-(GlcNAc)(2) rem

135 engendered with the ability to bind specific carbohydrate structures, thereby mediating cell-cell and

136 his study is the first to characterize which carbohydrate structures they can recognize.

137 We postulate that the unusual carbohydrate structures this molecule carries could inte

138 for small molecule analysis while lacking a carbohydrate structure to reduce nonspecific binding.

139 cterial samples, allowing dynamic changes in carbohydrate structures to be studied.

140 ay consisting of approximately 180 different carbohydrate structures to identify the specific sialosi

141 The complexity of carbohydrate structures, together with inconsistencies i

142 rd the goal of characterizing all aspects of carbohydrate structure using a single instrument.

143 purified to apparent homogeneity, and their carbohydrate structure was examined by high-pH anion-exc

144 The three carbohydrate structures were of the biantennary complex

145 VSG and LVSR (LVS strains altered in surface carbohydrate structures) were susceptible.

146 acids and proteins lies in the complexity of carbohydrate structures, which renders their analysis ex

147 To increase the knowledge of diversity of carbohydrate structures within this phylum, here we cond