ライフサイエンスコーパス: carbon-centered radical

1 te functionality via the ring opened primary carbon centered radical.

2 chanistic studies indicate the presence of a carbon centered radical.

3 )-C bond formation via the intermediacy of a carbon-centered radical.

4 substrate to generate a Ru-OH species and a carbon-centered radical.

5 ns, with CH(3)C(O)OO(*) as the most abundant carbon-centered radical.

6 tom transfer (HAT), forming a tertiary alkyl carbon-centered radical.

7 ed reactivity of a secondary versus tertiary carbon-centered radical.

8 e alpha-carbon of I3A to generate an initial carbon-centered radical.

9 are excellent acceptors for "electrophilic" carbon-centered radicals.

10 s context, enabling the direct generation of carbon-centered radicals.

11 ng of norbixin indicating the involvement of carbon-centered radicals.

12 ling meta-C-H functionalization reaction via carbon-centered radicals.

13 nd 4 was investigated by EPR for oxygen- and carbon-centered radicals.

14 um ion trapping of photochemically generated carbon-centered radicals.

15 fides are particularly attractive sources of carbon-centered radicals.

16 tylenes are efficient for alkyne transfer on carbon-centered radicals.

17 litated hydrogen atom transfer and resultant carbon-centered radicals.

18 activation of the endoperoxide to cytotoxic carbon-centered radicals.

19 ts as well as the stability of the resulting carbon-centered radicals.

20 artemisinin (1) forms primary and secondary carbon-centered radicals.

21 pathways forming relatively stable alpha-oxa carbon-centered radicals.

22 ficient photochemical production of reactive carbon-centered radicals.

23 stent with the rate of iodine abstraction by carbon-centered radicals.

24 mild conditions via controlled formation of carbon-centered radicals.

25 mediating carbon-carbon bond formation from carbon-centered radicals.

26 After formation of a cobalt-entangled carbon-centered radical, a sequence of hydrogen abstract

27 reaction is proceeding through addition of a carbon-centered radical across an olefin followed by oxi

28 ve a spectrum consistent with that of a POBN/carbon-centered radical adduct (aN=14.94+/-0.07 G and ab

29 Ethanol increased a carbon-centered radical adduct in bile approximately 2-f

30 on of a chemical reductant that has an alpha-carbon centered radical adjacent to the nitrogen center

31 trapping demonstrated that TBHP initiated a carbon-centered radical after 1 min of exposure in micro

32 ified two previously unrecognized classes of carbon-centered radicals, alkylaminocarbonyl and acyl ra

33 to those observed for the addition of other carbon-centered radicals, although the magnitude of the

34 radical ~6 angstroms away from the tertiary carbon-centered radical and suggest a means of controlli

35 MitoPBN did react with carbon-centered radicals and also prevented lipid peroxi

36 Given the sensitivity of ETPs to carbon-centered radicals and UV irradiation, we develope

37 rough a radical-radical recombination of the carbon-centered radicals, anthracene may plausibly be fo

38 from a metal hydride to directly generate a carbon-centered radical appears to be the most reasonabl

39 ns are characteristic of a cationic process; carbon-centered radicals are not known to rearrange in t

40 H bonds on the PDI ligand to yield HCl and a carbon-centered radical as determined by photocrystallog

41 ration of the 1-hydroxy-2,2,2-trifluoroethyl carbon-centered radical as key synthon, which undergoes

42 using anodic oxidation for the generation of carbon-centered radicals as the model reactivity profile

43 The resulting carbon-centered radical at C8 was utilized in a C-H amin

44 mation through the reaction of O2 with alpha carbon-centered radicals at 1 atm of N2 are estimated as

45 tert-butylnitrone, which reacts rapidly with carbon-centered radicals but is unreactive with superoxi

46 nitrones were also found to efficiently trap carbon-centered radicals, but complex spectra were obser

47 rder assessment indicate the trapping of the carbon-centered radical by the enamine, to form the carb

48 bon-cobalt bond, are largely used to produce carbon-centered radicals by homolytic cleavage of their

49 The corresponding carbon-centered radicals can be effectively trapped by a

50 Carbon-centered radicals can be stabilized by delocaliza

51 compounds, we demonstrate how electron-rich carbon-centered radicals can react with electron-rich ar

52 alarial effects by iron-induced formation of carbon-centered radicals capable of alkylating heme and/

53 lysts for the mild and tunable generation of carbon-centered radicals, chemists have developed a torr

54 catalyzed cross-coupling reactions involving carbon-centered radicals, control experiments and spectr

55 nitol) and singlet oxygen (sodium azide) and carbon-centered radicals (DMPO) were tested to determine

56 ogen atom from the alkane, and the resulting carbon-centered radical either recombines with the boryl

57 radical chain reaction involving peroxyl and carbon-centered radicals even though not detectable with

58 O(2) plays a vital role in the generation of carbon-centered radicals for both the addition of active

59 lcohols, the heart of which is a deaminative carbon-centered radical formation process using an anome

60 A broad computational analysis of carbon-centered radical formation via the loss of either

61 increasing the C-H BDE and destabilizing the carbon centered radical formed after abstraction.

62 Subsequently, the resulting remote carbon-centered radicals formed by C-C cleavage merge wi

63 Titration of the carbon-centered radical, formed following the initial OH

64 oceeds by a photoinduced reduction to afford carbon-centered radicals from alkyl halides, which under

65 ent ene-reductases enables the generation of carbon-centered radicals from iodinated fluoroalkanes, w

66 rogen atom transfer (HAT) approach to access carbon-centered radicals from unactivated substrates.

67 y coupling photocatalysis with Rh catalysis, carbon-centered radicals generated via photoredox cataly

68 gradation is likely initiated by OH(*), (ii) carbon-centered radicals generated via radical transfer

69 subsequent protein labeling via concomitant carbon-centered radical generation.

70 and also prevented lipid peroxidation by the carbon-centered radical generator 2,2'-azobis(2-methyl p

71 ulfonium ions are demonstrated to react with carbon-centered radicals, giving adducts that undergo in

72 H oxidant and Fe-OH rebounds with the formed carbon-centered radical guides the design of the prototy

73 the known pathways for transformation of the carbon-centered radical in Fe/2OG enzymes and suggests w

74 anner, and preliminary evidence implicated a carbon-centered radical in this process.

75 steady-state mechanism for the formation of carbon-centered radicals in cigarette smoke involving NO

76 ot in general appear to be a major source of carbon-centered radicals in fresh mainstream cigarette s

77 a convenient and powerful method to generate carbon-centered radicals in polymer chains.

78 e widely accepted mechanism of formation for carbon-centered radicals in the gas-phase cigarette smok

79 A transient carbon-centered radical intermediate (*QOOH) in the oxid

80 tigate the conformational flexibility of the carbon-centered radical intermediate.

81 peting mechanisms for oxygen delivery to the carbon-centered radical intermediate.

82 th of methods that provide access to crucial carbon-centered radical intermediates that can engage in

83 le highly enabling, functionalization of the carbon-centered radical is largely mediated by electroph

84 hat formation of either primary or secondary carbon-centered radicals is a necessary but insufficient

85 that the MNP adduct resulted from trapping a carbon-centered radical located on the aromatic ring of

86 radicals may transform intramolecularly into carbon-centered radicals located on the (alpha)C moiety

87 roethane underwent rapid dehalogenation when carbon-centered radicals produced by the reaction of eth

88 d Co(III)-F was the likely F-atom donor to a carbon centered radical producing a C-F bond.

89 ound aldehyde facilitating the addition of a carbon-centered radical (product of Ag-electrocatalyzed

90 i(IV) complexes through their reactions with carbon-centered radicals (R*).

91 s (or H shifts) to form primary or secondary carbon-centered radicals rather than further reduction o

92 a second electron transfer step to reduce a carbon-centered radical, rendering the overall process r

93 sters serving as precursors for nitrogen and carbon-centered radicals, respectively.

94 Applicable only to carbon-centered radicals, SE(H) stabilization energies a

95 dicals have been considered the prototypical carbon-centered radical since their discovery in 1900.

96 verted to induce the abiotic production of a carbon-centered radical species for targeted bioorthogon

97 studies suggested that the formation of the carbon-centered radical species occurred after or in con

98 plicate the in situ generation of a tertiary carbon-centered radical species.

99 evidence for the photochemical formation of carbon-centered radical species.

100 carbon bond formation results in a prochiral carbon-centered radical that engages with the chiral cat

101 perimental evidence that the lifetime of the carbon-centered radical that forms after the initial HAT

102 d by copper bromide in step (ii) to afford a carbon-centered radical that is spin-trapped in situ by

103 hydrogen atom transfer (HAT) generation of a carbon-centered radical that leads to engagement of a ni

104 vivo by newly released heme, which creates a carbon-centered radical that markedly reduces parasite d

105 sorbed on ZSM-5 zeolites produces persistent carbon-centered radicals that can be readily observed by

106 Complex 2b generates long-lived carbon-centered radicals that freely diffuse in solution

107 sulfur center proteins, which then generates carbon-centered radicals that initiate lipid peroxidatio

108 ss in N-pyridyl arylacetamides to form alpha-carbon-centered radicals that readily react with molecul

109 ate a pathway involving direct addition of a carbon-centered radical to the Ni(III) center.

110 Manipulating carbon-centered radicals to add to electron-deficient sy

111 Reactions that involve the addition of carbon-centered radicals to basic heteroarenes, followed

112 riethylborane at low temperatures to provide carbon-centered radicals to initiate the described organ

113 aph (HPLC) used to separate a broad suite of carbon-centered radicals trapped as the O-alkylhydroxyla

114 advances in methods to generate and utilize carbon-centered radicals under mild conditions.

115 The resulting carbon centered radical undergoes a second cathodic redu

116 C(sp(3) ) electrophiles that form stabilized carbon-centered radicals upon reduction or oxidation.

117 It was found that the number of carbon centered radicals was dependent on the kind of st

118 Alpha-amino acid carbon-centered radicals, well-known precursors of prote

119 een widely utilized as a strategy to produce carbon-centered radicals when cobalt is ligated by a pol

120 mers, the opposite behavior as seen in other carbon-centered radicals, where steric hindrance typical

121 light irradiation, these substrates generate carbon centered radicals, which have been applied to a b

122 g values of 2.0031-2.0033, characteristic of carbon centered radicals, while the radical signal in th

123 usion-controlled limit for the reaction of a carbon-centered radical with oxygen.

124 ck of an effect of ligands, the formation of carbon-centered radicals with long lifetimes, and the de