ライフサイエンスコーパス: carbonyl carbon

1 ve the greatest positive charge (but not the carbonyl carbon).

2 through nucleophilic attack of water on the carbonyl carbon.

3 positioned to react with the nitrile or the carbonyl carbon.

4 rotein catalysts of proton transfer at alpha-carbonyl carbon.

5 ard deprotonation of the alpha-hydroxy alpha-carbonyl carbon.

6 endant amines close (3.30 and 3.38 A) to the carbonyl carbon.

7 nsition state for proton transfer from alpha-carbonyl carbon.

8 ate-limiting attack by a hydroxide at a MIDA carbonyl carbon.

9 glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) at pD 7.0 in the presence

10 glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) catalyzed by triosephosph

11 Because carbonyl carbons ((13)C') suffer from serious relaxation

12 cts in the present investigation include the carbonyl carbon (13k = 1.028 +/- 0.001), the carbonyl ox

13 reaction for deprotonation of the weak alpha-carbonyl carbon acid substrate to form the enediolate ph

14 protonation of a wide range of neutral alpha-carbonyl carbon acids by hydroxide ion, from -0.40 to -1

15 nation of related neutral and cationic alpha-carbonyl carbon acids.

16 ilar decreases in the pK(a) of several alpha-carbonyl carbon acids.

17 c barrier to deprotonation of cationic alpha-carbonyl carbon acids.

18 bond of the acrylamide rather than the amide carbonyl carbon adjacent to the active site cysteine.

19 Alkyl substitution at the carbonyl carbon affects vibronic structure more profound

20 ble-quantum (DQ) coherences between adjacent carbonyl carbons along the peptide backbone.

21 g methanol molecules, a methanol adds to the carbonyl carbon and a proton relay occurs with formation

22 limination of a nickel alkoxide, between the carbonyl carbon and either one of the carbons of the ole

23 was attributed to a weaker bond between the carbonyl carbon and the three-membered ring in the forme

24 is to 2'-AADPR by the attack of water on the carbonyl carbon, and (4) an SIR2-independent transesteri

25 isotopic substitution at the alpha-hydrogen, carbonyl carbon, and carbonyl oxygen of the amino acid,

26 Chemical shift anisotropies of F12 and V16 carbonyl carbons are uniaxially averaged in 1,2-dilauryl

27 o a 1,3-shift of the C5 carbon atom from the carbonyl carbon atom (C1) to carbon atom C3.

28 s well as for the selective cyanation of the carbonyl carbon atom linked to the N atom of proline res

29 attack of a terminal ribose oxyanion on the carbonyl carbon atom of the adenylate.

30 -enzymes show similar key features, with the carbonyl carbon atom of the cleaved beta-lactam bond cov

31 l adduct between the C2 atom of ThDP and the carbonyl carbon atom of the MBP.

32 react with 1 via nucleophilic attack at the carbonyl carbon atom to give boryl-functionalized Fische

33 leophilic group that attacks the beta-lactam carbonyl carbon atom was eliminated.

34 sary for nucleophilic attack at the adjacent carbonyl carbon atom.

35 carbonyl showed that almost all Tyr and Leu carbonyl carbon atoms were approximately 0.5 nm from the

36 duct, wherein the no. 2 carbon (originally a carbonyl carbon) becomes substituted with -NH(2) and -OH

37 loadducts resulting from an attack of ketene carbonyl carbon beta to oxygen.

38 on or wobble dominates the relaxation of the carbonyl carbon by the alpha-CH(2) group.

39 ent to enable the nucleophilic attack on the carbonyl carbon by the catalytic cysteine.

40 nded these (15)N assignments to the adjacent carbonyl carbons by means of one-dimensional (13)C[(15)N

41 of the 1,2-dithiolan-3-one 1-oxide ring, the carbonyl carbon (C3') and the sulfinyl sulfur (S1') of t

42 Determination of the carbonyl carbon, carbonyl oxygen, and formyl hydrogen is

43 the C-terminal asparagine side chain on its carbonyl carbon, causing succinimide formation and simul

44 cular, the amide nitrogen, amide proton, and carbonyl carbon chemical shifts are highly sensitive to

45 e racemase inhibitor) reveal three different carbonyl carbon chemical-shift environments, arising fro

46 ultraviolet absorbance (SUVA), aromatic and carbonyl carbon contents, and molecular weight.

47 at a distance of 2.8-5.5 A from the aldehyde carbonyl carbon during the dynamics simulation.

48 ack of the bridging water on the beta-lactam carbonyl carbon, electrostatic stabilisation of a negati

49 ted a significant, positive correlation to % carbonyl carbon for the isolates studied, but relationsh

50 y was observed; only dihydropyrans where the carbonyl carbon forms a carbon-carbon bond with a carbon

51 n of two disparate nucleophiles to the amide carbonyl carbon in a single operational step.

52 addition of the hydroxide nucleophile to the carbonyl carbon in the substrate lactam ring leads to a

53 resonances arising from the heme propionate carbonyl carbons in OM cytochrome b5.

54 othane molecules are located below the lipid carbonyl carbons, in agreement with photolabeling experi

55 ion of the Gly67 amide nitrogen to the Ser65 carbonyl carbon is catalyzed by the protein fold and lea

56 The observed carbonyl carbon isotope effects [(13)(V/K)] were 1.0135

57 at is highly tetrahedral (Dkobs = 0.79); the carbonyl-carbon KIE (13kobs = 1.031) is in agreement wit

58 By rendering one carbonyl carbon less electrophilic and the other less st

59 l formate (1) enriched in 13C to 99% for the carbonyl carbon [methyl formate 13C (2)].

60 ng rise to 20-30 protein atom types, such as carbonyl carbons, methyl groups, and hydroxyl groups.

61 manifests itself and cyclization to the C-21 carbonyl carbon occurs.

62 H < 7, this carbanion reacts mainly with the carbonyl carbon of 1 to form a stable Claisen-type adduc

63 he catalytic cysteine thiol group toward the carbonyl carbon of a peptide bond or an electrophilic gr

64 (H3 peptide substrate) directly attacks the carbonyl carbon of AcCoA, transferring the acetyl group

65 CO attacks the carbonyl carbon of acetaldehyde in the coupling, and the

66 c attack of the thiolate anion of CoA on the carbonyl carbon of acetyl phosphate.

67 neral base, which then attacks the thioester carbonyl carbon of acetyl-CoA to yield a tetrahedral add

68 electron density of the ylide carbon to the carbonyl carbon of benzaldehyde at a C-C distance of 2.0

69 addition of the resulting gamma-anion to the carbonyl carbon of benzaldehyde, and intramolecular tran

70 amino group of L-ornithine which attacks the carbonyl carbon of carbamoyl phosphate in the enzyme-cat

71 e nitrogen of the amino group of Asp and the carbonyl carbon of carbamoyl phosphate.

72 dianion, which displays selectivity for the carbonyl carbon of chloromethyl carbonyl electrophiles.

73 odeled assuming a nucleophilic attack on the carbonyl carbon of D-Tyr by the Thr-80 O(gamma) atom and

74 sition the alpha amino group adjacent to the carbonyl carbon of esterified P site substrate in an ori

75 tack of an active site hydroxyl on the gamma-carbonyl carbon of gammaGlu-X with displacement of X.

76 ubstitution with two indole molecules at the carbonyl carbon of ortho-formyl (or ortho-acyl) cinnamat

77 complex, the active site serine attacks the carbonyl carbon of PNAA with general-base catalysis to f

78 ole complex of methanol weakly bonded to the carbonyl carbon of protonated acetyl chloride is stabili

79 ic attack of the coordinated NO(2)(-) to the carbonyl carbon of RC(O)Cl to generate RC(O)ONO, which,

80 it results in shorter distances between the carbonyl carbon of residue i and the amide nitrogen of r

81 ucleophilic attack of the amino group on the carbonyl carbon of the acyl adenylate.

82 erve to polarize the electrons away from the carbonyl carbon of the acyl group, thereby making it mor

83 p of Asp(17) is approximately 3.2 A from the carbonyl carbon of the acyl group.

84 ophilic attack of the phenolic oxygen on the carbonyl carbon of the acylpalladium complex with simult

85 tion of an adsorbed amide, which attacks the carbonyl carbon of the aldehyde, forming an adsorbed hem

86 accomplished by a nucleophilic attack at the carbonyl carbon of the amide linkage in the substrate, l

87 a slight lessening of bond stiffness at the carbonyl carbon of the amide of CA-asp.

88 anion produced by nucleophilic attack at the carbonyl carbon of the beta-acetoxy group.

89 by serine 195 of the catalytic triad on the carbonyl carbon of the carboxyterminal arginine.

90 pseudoequatorial hydrogen atom at C6 and the carbonyl carbon of the forming spirooxindole.

91 ullikan charge populations revealed that the carbonyl carbon of the highest-energy conformer was the

92 nitrogen lone-pair orbital and the other the carbonyl carbon of the ketene moiety.

93 volved in n --> pi( *) interactions with the carbonyl carbon of the preceding residue.

94 t carries out the nucleophilic attack on the carbonyl carbon of the scissile bond are present; it is

95 bridging solvent attacks the re face of the carbonyl carbon of the scissile peptide bond.

96 ely with its catalytic Cys esterified to the carbonyl carbon of the scissile peptide bond.

97 om Ser241 to Ser217, attack of Ser241 on the carbonyl carbon of the substrate, and elimination of the

98 r intermediate (the N-terminal amine and the carbonyl carbon of the thioester) increased as glycopept

99 arbenoid carbon of DFAY on the electrophilic carbonyl carbon of the ynal characterizes the cb-type re

100 Chemical shifts of three C-terminal carbonyl carbons of helix 2 titrate with the protonation

101 histamine could react with either of the two carbonyl carbons of methylglyoxal utilizing the a-amino

102 ion of multiple methylene groups between the carbonyl carbons of readily available alpha-diketones to

103 lar couplings between the labeled methyl and carbonyl carbons of the acetyl groups.

104 and in silico docking studies show that both carbonyl carbons of the curcumin molecule are highly sus

105 stance between the gamma-methyl and backbone carbonyl carbons of Thr-87 is consistent with a gauche-

106 with hydrogen atoms attached directly to the carbonyl carbon or to the alpha-carbon atom.

107 on involves nucleophilic water attack at the carbonyl carbon, proton transfer to the amide nitrogen l

108 so includes the AM1-calculated charge on the carbonyl carbon (q(C=)) and a calculated log octanol-wat

109 en abstraction from the aldehyde to give the carbonyl carbon radical.

110 The carbon spectrum showed two peaks in the carbonyl carbon region of nearly equal intensities at -1

111 t the strong electronic stabilization of the carbonyl carbon, resulting from the GEDT taking place at

112 o direct regioselectivity by correlating the carbonyl carbon shifts of salicylamides to the regiosele

113 In addition, an inhibitor carbonyl carbon that mimics the scissile carbonyl of sub

114 activated asparagine attacks its main-chain carbonyl carbon, the resulting oxyanion is stabilized by

115 Cys, Ser, or Thr side chain and the backbone carbonyl carbon to form a thiazoline, oxazoline, or meth

116 ogen (1.20 A) and partial bond loss from the carbonyl carbon to the amide leaving group (1.52 A).

117 d includes three main steps: the addition of carbonyl carbon to the ipso carbon of the aryl ether fol

118 217, and attack of Ser241 on the substrate's carbonyl carbon to yield a tetrahedral intermediate, whi

119 stance between the fluorine and the 3'-amide carbonyl carbon was 9.8 +/- 0.5 A, and the distance betw

120 product was derived from methane, while the carbonyl carbon was derived from TFAA.

121 OM contained significantly more aromatic and carbonyl carbons whereas Marine DOM was markedly enriche

122 -->pi* overlap of the amide oxygen and ester carbonyl carbon, which favors a trans amide bond.

123 of the Zn(II)-OH oxygen on the benzaldehyde carbonyl carbon, which has an O...C distance of 1.877 A.

124 ectrons at the electrophilic beta-carbon and carbonyl carbon, while a slight increase in electron den

125 ough-space electrostatic interactions of the carbonyl carbon with the Cl ligands bound to Si, rather