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1 ion of the peptide (detected by formation of carbonyl groups).
2 utomer forms a hydrogen bond with the flavin carbonyl group.
3 atoms and the antibonding orbital of the BPL carbonyl group.
4 tronger coordination of the more basic amide carbonyl group.
5 ereogenic centres are proximal to the active carbonyl group.
6 the alcohol, resulting in the formation of a carbonyl group.
7 he acid-catalyzed nucleophilic addition to a carbonyl group.
8 try leads to burial of an unmatched backbone carbonyl group.
9 e with eta(2) coordination of lithium by the carbonyl group.
10 y introducing an oxygen atom adjacent to the carbonyl group.
11 tion of tertiary stereocenters adjacent to a carbonyl group.
12 rs by using the hydrazone moiety as a masked carbonyl group.
13 toreductase (KR) specifically reduces the C9-carbonyl group.
14 ng in the ortho position with respect to the carbonyl group.
15 the allylic ester by hydrogen bonding to its carbonyl group.
16 e group of the peptide linkage or a backbone carbonyl group.
17 rs with the least crowded space around their carbonyl group.
18 hich may be ascribed to the influence of the carbonyl group.
19 abilization of carbene intermediates via the carbonyl group.
20 two different silicon groups rather than the carbonyl group.
21 ]pyridines via reaction at the less reactive carbonyl group.
22 functional groups and/or multiple enolizable carbonyl groups.
23 A complex linked by the THC hydroxyl and VEA carbonyl groups.
24 ulfhydryl groups and immuno-blotting against carbonyl groups.
25 he mechanism of the nucleophilic addition to carbonyl groups.
26 l groups, including olefins, furan rings and carbonyl groups.
27 tion of heteroatom-stabilized oxyallyls onto carbonyl groups.
28 ork is predicted to involve multiple peptide carbonyl groups.
29 ts of alkane, carboxylic acid, hydroxyl, and carbonyl groups.
30 and hydroxyl groups and leaves only nonacid carbonyl groups.
31 state modes arising directly from the flavin carbonyl groups.
32 , highly branched oxygenated aliphatics, and carbonyl groups.
33 terms of direct alkylation reactions of some carbonyl groups.
34 sponded mainly to organic OH, mineral OH and carbonyl groups.
35 ations involving orbitals extending onto the carbonyl groups.
36 ron-rich aromatic rings rather than adjacent carbonyl groups.
37 il), TBARS values (8.8-10.2 nmol MDA/g), and carbonyl groups (2.6-3.5 nmol/mg of protein) occurred.
38 constituents: (1) intact HOMs that contain a carbonyl group, (2) particle-phase decomposition product
39 ltant beta-borylalkenyl radical to the ester carbonyl group; 3) beta-scission of the so-formed alkoxy
40 yl carboxylate groups all trans and the four carbonyl groups aligned in a pinwheel arrangement around
42 etween a lone pair in the oxygen atom of the carbonyl group and an empty p orbital in the phosphorous
43 creased the electrophilicity of the adjacent carbonyl group and decreased the basicity of the hydroxy
44 hyde by two effects, that is, polarizing the carbonyl group and increasing the probability of forming
47 activated through a halogen bond between the carbonyl group and the catalyst, and other modes of acti
51 Recent strategies for installing reactive carbonyl groups and alpha-nucleophiles into biomolecules
54 Mechanistically, the coordination of these carbonyl groups and the bisdentate amino acid ligand wit
55 ies showed that the -CO groups (carboxyl and carbonyl groups) and -OH (hydroxyl) functional groups of
56 of flap residue Gln73 and the acyl guanidine carbonyl group, and a cation-pi interaction between Arg2
57 the hydrogen bond acceptor is the lipid acyl carbonyl group, and this interaction contributes signifi
58 ent with concentration enrichment near lipid carbonyl groups, and permeability coefficients are suffi
59 n is directly coordinated by five main chain carbonyl groups, and we show this site is essential for
60 rotons within the channel are very slow, the carbonyl groups appear to adopt a single conformation/en
61 es reveals that more than 30% of the proline carbonyl groups are also involved in n --> pi( *) intera
62 e Wieland-Miescher homologue 3 whose pair of carbonyl groups are amenable to regiochemical manipulati
64 r conditions, analogous substrates bearing N-carbonyl groups are converted to 1,4,2-oxazaborole deriv
70 MthK's S2 site due to weaker coordination by carbonyl groups, arising from different interactions wit
71 lkyl stabilized by coordination of the ester carbonyl group as a four membered chelate [(P^P)PdCH{(CH
72 he ene moiety and equipped with aromatic and carbonyl groups as internal triplet sensitizer units at
73 nal approaches, we show that relevant amidic carbonyl groups associate through an n-->pi* donor-accep
75 ated that the incorporation of silicon and a carbonyl group at C-4 in the WA framework enhances poten
76 lutamine that follows beta-strand 1 with the carbonyl group at C6, a conserved tyrosine that follows
79 designed by bioisosteric replacement of the carbonyl group at position 2 in a series of 3,4-dihydrop
80 sis of DPO analogs showed that a hydroxyl or carbonyl group at the 2'-position is critical for bindin
82 ding pocket via the reorientation of Ile-205 carbonyl group at the irregular portion of transmembrane
84 rbon exhibits a lower abundance of available carbonyl groups at the interface compared to the results
87 nal preferences and electronic properties of carbonyl group-bearing lithium derivatives are also disc
88 ne transporter (VAChT), we have interposed a carbonyl group between the phenyl and piperidyl groups o
89 lvent effect and the polarized nature of the carbonyl group, both of which have been analyzed through
90 ) reaction allows the difunctionalization of carbonyl groups by a radical-carbanion relay sequence (p
91 nd over the antibonding orbital (pi*) of the carbonyl group (C(i)=O(i)) of the subsequent peptide bon
93 e bond equivalents and one oxygen beyond the carbonyl group), C(18)H(29)O(3) (18:3-O), C(18)H(31)O(3)
94 ts of carbamazepine containing a hydroxyl or carbonyl group can be fully mineralized by a mixed bacte
95 ur analysis reveals that water molecules and carbonyl groups can both provide K+ selective environmen
96 y favored lone-pair interaction whenever the carbonyl group carries electron-donating substitutents,
97 n of acidic sites, NH2OH for the presence of carbonyl groups, CF3COOH and HCl for basic sites of diff
99 Molecular modeling suggests that moving the carbonyl group closer to the active site blocks access f
101 s to functionalization by carboxylic acid or carbonyl groups, consistent with a decreased OH:HO2 rati
103 Thr196 residue of SpnF and the substrate C15 carbonyl group contributes to the enhancement of the rat
105 ating between the two equivalent overhanging carbonyl groups, coupled to an intermolecular pathway fo
107 gnesium chelate with the reacting alkoxy and carbonyl groups dictates the observed reactivity and sel
108 led to polycarbonyl compounds with tailored carbonyl group distances which could be characterized vi
110 We find that frequency shifts of the local carbonyl groups due to nearest neighbor couplings and en
111 way, substrates containing multiple reactive carbonyl groups (e.g., dialdehyde or triketone) can be s
114 coordinating ligand is a water molecule or a carbonyl group, "external" or "topological" constraints/
115 n conductivity is abrogated if some of these carbonyl groups flip out of the lumen, which happens (i)
118 vity in proximity to the weakly coordinating carbonyl group for a range of substituted phenones and a
122 ocalization, the n-->pi* interaction between carbonyl groups, has been shown to play a role in stabil
123 ormed by one-electron reduction of the ester carbonyl group have been exploited in intramolecular add
125 odologies developed for preparation of (11)C-carbonyl groups have had a tremendous impact on the deve
126 ation) or carbonylation by activation of the carbonyl group (i.e., via the formation of enamines).
127 embered-ring cyclic enediynes that possess a carbonyl group in a beta position with respect to the on
133 fects are apparent at the surface; e.g., the carbonyl group in the methyl vinyl ketone transition str
134 The key step involved the substitution of a carbonyl group in the parent compound with a sulfonyl in
139 ipole coupling of the vibrations of backbone carbonyl groups in helix G with the side chain of Tyr57
140 Loss of the interaction of the backbone carbonyl groups in helix G with Tyr57 and the Schiff bas
141 oride for labeling heterocycles with [(11) C]carbonyl groups in high molar activity is described.
142 urface characterization and the detection of carbonyl groups in oxidized protein were performed by vo
144 electrochemical sensor for the detection of carbonyl groups in proteins oxidized by reactive oxygen
149 tainment of such proximal arrangement of the carbonyl groups in the absence of the n --> pi* interact
150 ic peroxides via the monoperoxidation of the carbonyl groups in the beta-positions and the transforma
151 lysine residue results from interactions of carbonyl groups in the motif backbone with basic side ch
153 n the degeneration of H2O2, the formation of carbonyl groups in the peptide, and in aggregate morphol
155 DHQD-PHN differentiates the two enantiotopic carbonyl groups in the transition state of the asymmetri
156 e that acetoxylation adjacent to the lactone carbonyl group, in either the bridged or fused series, i
157 n the regions corresponding to phosphate and carbonyl groups, indicating detection of phospholipid-ri
158 titution: fluorine on carbon adjacent to the carbonyl group induces higher lipophilicity than fluorin
159 urine orients in the active site with its C2 carbonyl group interacting with Arg-880 and extends our
160 r of 1a-DFT, which leads to insertion of the carbonyl group into an Si-H bond (that is part of a Ru-H
162 ne transporter inhibitor that incorporates a carbonyl group into the benzovesamicol structure was syn
164 of early leads was achieved by introducing a carbonyl group into the phenethylpiperazine linker.
165 up of Tyr(318), respectively, whereas the C3 carbonyl group is at hydrogen bonding distance from the
166 C(16)) and an appropriately orientated ester carbonyl group is essential for TLR2-agonistic activity.
169 none that has asymmetrically hydrogen bonded carbonyl groups is also predicted to display this behavi
170 on at positions adjacent to double bonds and carbonyl groups is discussed in this critical review.
171 s, the intimate interaction between adjacent carbonyl groups is shown to arise primarily from n-->pi*
172 groups activate methyl ketones through their carbonyl groups leading to a favorable CC bond formation
173 el H-bond interactions with the two backbone carbonyl groups, leading to the first thumb pocket 2 NS5
174 rophile preorganization by coordination to a carbonyl group likely play a role in controlling the rea
177 ease in mitochondrial NAD(+)/NADH and direct carbonyl group modification of SIRT3, and is reversed wi
178 ycle, TRCD provides strong evidence that the carbonyl group moves back to its initial position, leadi
179 However, the hydroxyl group of 5hmC and carbonyl group of 5fC face towards the opposite directio
180 hemoselective (3 + 2) cycloaddition onto the carbonyl group of a tethered dienone in preference to fo
183 lorides was circumvented by transforming the carbonyl group of aromatic ketones or aldehydes into the
184 ety being the most preferred followed by the carbonyl group of aryl aldehyde and the aryl methane.
189 MT-ND1 with the sidechain of E4 and backbone carbonyl group of M1 of NDUFA1 (NADH dehydrogenase [ubiq
190 purpose of the H-bond is to tie up the C(4) carbonyl group of phylloquinone in a H-bond so as to pre
191 explained by the orientation of the backbone carbonyl group of Q68, which differs by approximately 82
192 d between a hydroxyl group of TETROL and the carbonyl group of the (R)-enantiomer (O...O 2.621(2) A)
193 urns the electric dipole associated with the carbonyl group of the amino acid preceding the proline i
194 a strong hydrogen bond, from FAD N5-H to the carbonyl group of the Asn378 side chain, that is modulat
195 the anti-glioblastoma activity, including a carbonyl group of the benzophenone moiety, as well as 4'
197 tween the His(195) nitrogen backbone and the carbonyl group of the coumarinyl molecule to develop a t
198 derived from the catalyst interacts with the carbonyl group of the cyclic acyloxyborane, stabilizing
202 alyst donates two hydrogen bonds to the keto carbonyl group of the Nazarov reactant and the primary a
204 that is adjacent to nitrogen closes onto the carbonyl group of the phenyl carbamate unit at the other
206 His-143 is positioned to help polarize the carbonyl group of the substrate in conjunction with Lewi
207 oved to be two stable rotamers, in which the carbonyl group of the tert-butyl ester was oriented towa
208 (NDIs) are incorporated into PPN films, the carbonyl groups of adjacent, electrochemically generated
209 undergoing Zr(+)/P addition reactions to the carbonyl groups of an alkyl isocyanate and of carbon dio
210 ing sites (S(0)-S(4)) formed by the backbone carbonyl groups of conserved residues common to all K(+)
211 and second reductions, respectively, of the carbonyl groups of DTED) and kinetic effects between sma
213 m transition dipole coupling of the backbone carbonyl groups of Glu204, Phe208, Asp212, and Lys216 in
215 covalent attractive interactions between the carbonyl groups of MTFP and the amine and aromatic group
216 ix membered binding core of lithium ion with carbonyl groups of purpurin and hydroxyl groups at C-1 a
217 rentiation to be made of the four equivalent carbonyl groups of pyromellitic dianhydride (PMDA, benze
218 calculations do not predict that one of the carbonyl groups of Q(A) is very strongly hydrogen bonded
219 oms, the electrostatic repulsion between the carbonyl groups of the CB7 molecules avoids the threadin
222 for O...I) and the other one with the ureido carbonyl groups of the molecular container itself (bond
224 yses of four potent inhibitors revealed that carbonyl groups of the new P2 moieties promote extensive
225 It has been shown that upon interaction with carbonyl groups of the oxidized protein, the oxidation p
227 r evidence for our early hypothesis that the carbonyl groups of the potassium carboxylate are respons
228 tution of both oxygen atoms in the exocyclic carbonyl groups of the thymine chromophore by sulfur ato
231 up and hydrogen bonding through the adjacent carbonyl group on the quinoline ring resulted in success
232 he hydroxyl groups on pillar[5]arene and the carbonyl groups on cucurbit[6]uril form hydrogen bonds r
233 ited enhanced cleavage between the amine and carbonyl groups on the 2- and 2'-linked primary acyl cha
234 r sidechains due to its additional amino and carbonyl groups on the damaged tryptophan sidechain, thu
235 has a reversed orientation and projects its carbonyl group out of the concave face in the vicinity o
238 gamma-keto esters in high yields, through a carbonyl group participation enabled by a favored 5-endo
239 onceivable sites, that is, at C and O of the carbonyl groups (pathways a, b) as well as at halogenate
243 ce carboxyl groups and the redox activity of carbonyl groups promote enhanced MWNT reactivity and elu
244 evaluated on protein oxidation (by measuring carbonyl groups), protein nitrosation (by measuring nitr
245 n bonds between the C2 amine and Leu16/Leu19 carbonyl groups provide for specific guanine recognition
246 nucleophilic nitrogen atom and electrophilic carbonyl group provided some initial evidence for variou
247 llowed by in situ reduction of the resulting carbonyl group, provides functionalized indenes in good
248 ently bound to the inhibitors' electrophilic carbonyl groups, providing the first structures of FAAH
249 t hydride transfer is directed toward the C3 carbonyl group rather than the Delta(4)-double bond and
250 re cyclization proceeds on the oxygen of the carbonyl group rather than the nitrogen of the amide fun
252 ng and an Au...O contact involving a thymine carbonyl group, resolving the ambiguity of conventional
254 is opposite to the electrophilicity of polar carbonyl groups resulting from the n(X) --> pi*(C horizo
255 yclized GNRs induces cleavage of sacrificial carbonyl groups, resulting in atomically well-defined he
256 ntrations of 1-4, the alpha,beta-unsaturated carbonyl group seems to be an indispensable moiety for a
257 Such a proximal arrangement of the amide carbonyl groups should be opposed by the Pauli repulsion
258 rboxylic acid, organic hydroxyl, and nonacid carbonyl groups similar to those observed for isoprene a
259 the peak at around 1740cm(-1) (due to ester carbonyl group stretching) to the sum of the intensities
260 kyl groups, alkenes, acidic protons alpha to carbonyl groups, tertiary amides, and aryl rings having
261 Schiff base formation between Lys99 and the carbonyl group tethers the enzyme to the flavin via a th
262 Ni(OEPone) was chosen because it contains a carbonyl group that can be easily observed in infrared s
263 utions at the alpha-position proximal to the carbonyl group that normally render these beta-lactams r
266 C-4' 4-methoxyphenoxy and 4-(o-fluoropyridyl)carbonyl groups that showed low nanomolar in vitro antip
267 ne, not the location of the constrained C-20 carbonyl group, that prevents Delta(16)-alphaxalone from
268 he 8-aryl group is a phenyl ring with a meta-carbonyl group, the resulting supramolecule is a hexadec
269 tal of the carbene with the pi system of the carbonyl group, the same factor that makes methyl ketone
271 ascorbate and peroxide produces new protein carbonyl groups, their positions can be identified using
273 e radical scavenging capacity, protein-bound carbonyl groups, thiol groups and metal chelation activi
274 (16) double bond constraining the steroid 20-carbonyl group to a position that prevents it from favor
276 ntermediate which cyclizes onto the adjacent carbonyl group to give a reactive benzo[c]furan which in
277 ncreases the susceptibility of a coordinated carbonyl group to nucleophilic addition in the former, f
278 f the amide spacer and the direct linkage of carbonyl group to the gamma-pyrone ring, along with the
279 ese isomers and just as the reduction of the carbonyl group to the hydroxy-group negates this differe
282 -) charge-dipole attraction compel the amide carbonyl groups to orient antiperiplanar to the C-F bond
283 and effectively polarizes the electrophilic carbonyl group toward a nucleophilic attack by CN(-) in
284 d diphenylacetylene turn motif activates the carbonyl group toward nucleophilic attack, and chemical
285 tirely metal-free catalytic hydrogenation of carbonyl groups under relatively mild reaction condition
286 the signals shows that, upon excitation, the carbonyl group undergoes a fast (<<0.8 ps) and unidirect
287 eduction of the triple bond, addition to the carbonyl group (using carbon- and heteronucleophiles and
288 unctionality of the oxygen atom of the ester carbonyl group via noncovalent interaction, which provid
289 f zerumbone, alpha-humulene, which lacks the carbonyl group, was found to be inactive in inducing CXC
291 methylaminonaphthalene (PRODAN) with twisted carbonyl groups were investigated as highly responsive s
294 ypes of damages, to the production of stable carbonyl groups, which can be used as a quantification o
295 mistry, alcohols are important precursors to carbonyl groups, which then can be converted into a wide
297 The reaction involves methylenation of the carbonyl group with tetrahydrothiophenium ylide followed
298 odology enables the direct introduction of a carbonyl group without the requirement of unmasking step
299 strategies for the construction of versatile carbonyl groups, without the requirement of pre-function