ライフサイエンスコーパス: carboxyl group

1 d moieties of the PS molecule (phosphate and carboxyl groups).

2 al elucidation of lipid species containing a carboxyl group.

3 quantify the individual species containing a carboxyl group.

4 trength, and distance from the charge to the carboxyl group.

5 s of the inhibitor are its indole ring and a carboxyl group.

6 d presence or steric accessibility of a free carboxyl group.

7 rom the FBP C(4) hydroxyl group to the Asp83 carboxyl group.

8 Cs due to the altered spatial orientation of carboxyl group.

9 ly unaffected by the ionization state of the carboxyl group.

10 nt tissues through methylation of IAA's free carboxyl group.

11 and Tyr156 co-ordinate the ligand side-chain carboxyl group.

12 ronic resonance of the intrinsically achiral carboxyl group.

13 ween a conserved cysteine and the C-terminal carboxyl group.

14 ing substrate specificity, and orienting the carboxyl group.

15 at this residue cannot be substituted at its carboxyl group.

16 nism was assigned to the dissociation of the carboxyl group.

17 hogonal cross-linking chemistry specific for carboxyl groups.

18 3 proved to reliably assess deprotonation of carboxyl groups.

19 ncing the sensitivity due to the presence of carboxyl groups.

20 ol) and macrocyclic lactones linking the two carboxyl groups.

21 ly recognizing the protonation status of the carboxyl groups.

22 nctioning to "protect" the proline amino and carboxyl groups.

23 various number of (18)O-atoms to the peptide carboxyl groups.

24 acid for (18)O-labeling of peptides at their carboxyl groups.

25 are incorporated into the peptide C-terminal carboxyl groups.

26 ts in 95-97 atom % incorporation of (18)O at carboxyl groups.

27 cular hydrogen bonding to the propionic acid carboxyl groups.

28 e to steric hindrance between the methyl and carboxyl groups.

29 h amide bonds at both their alpha- and gamma-carboxyl groups.

30 mework (COF), COF-616, bearing pre-installed carboxyl groups.

31 e first oxidized to carbonyl groups, then to carboxyl groups.

32 the like-charge ion pair and the C-terminal carboxyl groups.

33 and proton transfer involving the phenol and carboxyl groups.

34 identate-mononuclear U(IV/VI) complexes with carboxyl groups.

35 lic component, this latter incorporating two carboxyl groups.

36 gels containing different amounts of grafted carboxyl groups (1-10%) was done using quartz crystal mi

37 ure the dynamics of the side chain amide and carboxyl groups, (13)C(gamma/delta), in Escherichia coli

38 ethylaminophenyl (4), 4-nitrophenyl (5), and carboxyl group (6) as substituents at the exocyclic doub

39 ric replacement of the tetrazole ring with a carboxyl group (60, IC(50) = 68 nM) gave a promising new

40 lectronic effects from the 2-thio- and the 6-carboxyl groups, a lability that could, in turn, be usef

41 ry activity of C4S, whereas reduction of the carboxyl groups abrogated the activity.

42 celerated in parallel to the extent that the carboxyl group acquires a second proton (1H(+)).

43 Substrates having functionalities such as carboxyl groups, alcohols, or heterocycles in the vicini

44 Incorporation of (18)O into one carboxyl group allows investigation of the symmetry of t

45 The introduction of carboxyl groups allows covalent conjugation of biologica

46 rmation from primary amines with hydroxyl or carboxyl groups (amino acids), but not from secondary am

47 ree arginines that accommodates the terminal carboxyl group and a dedicated cavity that facilitates b

48 leavage between the lone double bond and the carboxyl group and defining the position of the lone dou

49 involves 2-phenylisopropyl protection of the carboxyl group and does not require excesses of commerci

50 te cleft, in conjunction with the C-terminus carboxyl group and His267 of a partner subunit forms a t

51 g a conjugated tetraene fluorophore near the carboxyl group and natural methylene-interrupted n-3 or

52 -center hydrogen-bonding pattern between the carboxyl group and the phenolic oxygen atom(s).

53 The ASMA ligand features 2 carboxyl groups and an amine function for the coordinati

54 -1) corresponded to methyl esterified uronic carboxyl groups and confirmed the higher equivalent weig

55 rongly suggest that the reduction of surface carboxyl groups and the redox activity of carbonyl group

56 These data demonstrate that the C4S carboxyl groups and their equatorial orientation but not

57 functionalities such as hydroxyl or multiple carboxyl groups and to distinguish between isomers.

58 led and chemically modified to have terminal carboxyl groups and used as variably sized probes to stu

59 antiradical moieties (catechol, guaiacyl and carboxyl group) and molecular conformation in antioxidat

60 sting the alkyl chain lengths of the pendent carboxyl groups, and preferred conformations were predic

61 hat in tryptic/Lys-C peptides the C-terminal carboxyl group appears to be in a zwitterionic bond with

62 d a fluorescent oxazole (5) having amine and carboxyl groups approximately the same distance apart as

63 tagging strategy, in which metabolites with carboxyl groups are chemically tagged with (15)N-ethanol

64 e aqueous-lipid interface, fatty acids whose carboxyl groups are positioned toward the aqueous phase

65 -accommodating pocket, where alpha-amino and carboxyl groups are stabilized by salt bridges, and the

66 additional polar functional group such as a carboxyl group (as in 3x) or a monosaccharide (as in 4x

67 local scrutiny of protonation states of the carboxyl group, as had been suggested by Arg-bound AdiC

68 Finally, the carboxyl group at C10 is methylated by TcCCMT, a member

69 a complete dissociation of the alpha-hydroxy carboxyl group at pD < 4.

70 Addition of a carboxyl group at the alpha position of carbocyclic nucl

71 ch was placed in position B26, and the alpha-carboxyl group at the C terminus of the A chain (A26).

72 s, as predicted, deoxycholate bound with its carboxyl group at the entrance of the K path.

73 linear peptides that contained a free alpha-carboxyl group at their C-termini but remained covalentl

74 Ionisation of carboxyl groups at all tested pH values, and increased b

75 Lack of the amino or carboxyl groups at the alpha-carbon does not prevent the

76 ertion at ~pH 4 driven by the protonation of carboxyl groups at the inserting end of the peptide.

77 bination of readily functionalized amine and carboxyl groups attached to a chiral central core along

78 irs within 3 A, suggesting that at least one carboxyl group bears a proton.

79 thered biotin cofactor to carry an activated carboxyl group between distantly spaced active sites.

80 ly attached biotin as a vector to transfer a carboxyl group between donor and acceptor molecules duri

81 tively, the H2O loss did not derive from the carboxyl group but involved the sulfinyl oxygen, a proto

82 in thiol in cysteine is more acidic than the carboxyl group by 3.1 kcal mol-1.

83 ebactin via PubC-catalyzed activation of the carboxyl group by adenylation, followed by PubC-catalyze

84 e of hydrophobic acetyl groups, carbonyl and carboxyl groups caused a partial disorganization and dep

85 prisingly high water affinity of the neutral carboxyl group, comparable to that of the charge-carryin

86 GO chemical properties including C/O ratios, carboxyl group concentrations, and C-C fractions.

87 ng this tag, we demonstrate the detection of carboxyl group containing metabolites in both human seru

88 tter receptors that are activated by various carboxyl-group-containing compounds play a central role

89 The optimal carboxyl group content was determined to be 5%.

90 hydrogen bonds and other interactions of the carboxyl groups contribute over 8 kcal mol(-1) to the st

91 oups in heparin (N-sulfates, O-sulfates, and carboxyl groups) contributed to binding, consistent with

92 ssesses a shortened carbon chain and lacks a carboxyl group, cysteamine displays a catalytic efficien

93 With a high concentration of protons from 12 carboxyl groups decorating every edge of the cube and an

94 ose with high salinity may, in part, control carboxyl-group density on organic carbon surfaces, consi

95 be achieved by permethylation or by specific carboxyl group derivatization with the possibility of di

96 he desired oligosaccharide containing a free carboxyl group derived from CPB was attached to an amino

97 ensing reagents for activation of free alpha-carboxyl groups, despite reports that this chemistry may

98 an electrophile in the P site other than the carboxyl group during elongation.

99 be incorporated into the peptide C-terminal carboxyl group during enzymatic digestion.

100 the relatively shallow hydrophobic pore; its carboxyl group emerges at the receptor surface and is st

101 imethylamino)propyl)carbodiimide activates a carboxyl group followed by nucleophilic attack by benzhy

102 e positions of the newly generated amino and carboxyl groups following the 2 steps in the hydrolytic

103 protein-binding sites, we implemented a new carboxyl group footprinter, benzhydrazide, and refined i

104 orm HER2-HER3 kinase domain heterodimers and carboxyl group footprinting mass spectrometry, we observ

105 dation of proteins (FPOP), and site-specific carboxyl group footprinting to investigate the HOS of pr

106 ast photochemical oxidation of proteins, and carboxyl group footprinting with glycine ethyl ester, we

107 line core and the lack of the necessity of a carboxyl group for activity make them an attractive and

108 owed variant conjugation positions and freed carboxyl groups for other potential uses.

109 d range of substrates (e.g. metabolites with carboxyl groups) for various applications, including bio

110 n by proton-coupled electron transfer to the carboxyl group forming dihydroxymethyl radical intermedi

111 show that the ethylamido derivative of the 5-carboxyl group from 5-carboxy-fluorescein diacetate or f

112 ecarboxylase that catalyzes the removal of a carboxyl group from a d-stereocenter.

113 nsferase subunit catalyzes the transfer of a carboxyl group from biotin to acetyl-coenzyme A (acetyl-

114 ectroscopy (TRLFS) identified phosphoryl and carboxyl groups from bacterial envelopes, among other re

115 UVA irradiation removed carboxyl groups from COOH-MWCNT surface while creating o

116 hydrogel based on N-isopropylacrylamide with carboxyl groups grafted to the chains enabled the immobi

117 NaH in THF (i.e., in the presence of a free carboxyl group) has been attributed to the protection of

118 1-19 methylene and bis-terminal hydroxyl and carboxyl groups have been synthesized and evaluated in b

119 ng histidine or arginine residues and a free carboxyl group (His-Ala-Ile, His-Ala-Leu, Ala-His-Leu, A

120 profloxacin had peaks related to the ionised carboxyl group, i.e., at 1576 and 1392 cm(-1), which wer

121 roups and precluded in the absence of a free carboxyl group in His-Ala-Leu amide.

122 in despite the absence of a second conserved carboxyl group in the active site.

123 y line the proton inlet path to an essential carboxyl group in the c-subunit in the proton uptake sit

124 nyl)ethoxy-1,3,2-dioxaphospholane, bearing a carboxyl group in the gamma-position with respect to the

125 the alanine residue clashing with a critical carboxyl group in the gammaC hole but being accommodated

126 These aspartates have their terminal carboxyl group in the pore lumen, which take up much of

127 A free carboxyl group in the product provides versatility for f

128 f a lysine side chain in the peptide and the carboxyl group in the reagent.

129 Here we show that OprD channels require a carboxyl group in the substrate for efficient transport,

130 The contents of the carbonyl and carboxyl groups in a starch molecule therefore indicate

131 Acidic protons from carboxyl groups in both the lignite HA fraction and a sy

132 solubilize amino acid derivatives with free carboxyl groups in CDCl(3) and to mediate their interact

133 n peroxide has no effect on the iron binding carboxyl groups in CyaY, allowing the protein to bind ir

134 s of GAX, followed by more moderate PREs for carboxyl groups in homogalacturonan and rhamnogalacturon

135 demonstrate location-dependent ionization of carboxyl groups in NF polyamide films.

136 fers functionalized products with acetyl and carboxyl groups in one step, in good yields, and with sh

137 -exchange kinetics for individual side-chain carboxyl groups in proteins has been achieved in only a

138 are able to markedly lower the pK values of carboxyl groups in proteins.

139 The two most buried carboxyl groups in ribonuclease Sa (RNase Sa) are Asp33

140 ves as a "stinger" and penetrates a triad of carboxyl groups in the S3-S4 linker of the voltage senso

141 ow) insertion peptide] to study the roles of carboxyl groups in transmembrane (TM) peptide insertion.

142 tinct frequencies from cell wall protein and carboxyl groups, indicating that bacterial adhesion occu

143 yclized between their N-terminal amine and a carboxyl group installed at a C-terminal linker sequence

144 Both conformations have the LN-1-255 carboxyl group interacting with Arg-244, yet the remaini

145 the V-shaped pockets, respectively, and the carboxyl group interacts with S(gamma) of C110 by formin

146 The structure revealed that the substrate carboxyl group interacts with the side chains of Arg45,

147 izing a second polymerization to incorporate carboxyl groups into the HEMA PCCA.

148 on nanotubes (CNTs; with and without surface carboxyl groups) into polyacrylonitrile (PAN) and polyst

149 Specifically, only surface carboxyl groups ionize under neutral pH, whereas interio

150 a K(+)-ionophore, provided that the glycine carboxyl group is appropriately masked.

151 s buried within the protein, and the exposed carboxyl group is bound by a Ser-93-fatty acid carboxyl-

152 A lysine instead of the usual carboxyl group is in place of the internal proton donor

153 Furthermore, the carboxyl group is involved in binding N-acetyl-l-ornithi

154 the inhibitory compounds is enhanced when a carboxyl group is linked to the alpha-carbon.

155 n tail is buried in the cavity of TL and the carboxyl group is oriented toward the mouth.

156 The carboxyl group is removed by the MccE enzyme, yielding m

157 However, removal of the carboxyl group is the only modification tested that remo

158 results establish that a properly positioned carboxyl group is the sole requirement for autocatalytic

159 to the carboxyltransferase domain, where the carboxyl group is transferred from biotin to pyruvate.

160 coumermycin A1 biosynthesis, the pyrrolyl-2-carboxyl group is transferred from the peptidyl carrier

161 he decarboxylation of the kinetically stable carboxyl groups is proposed.

162 The key structural difference between the carboxyl groups is that Asp33 forms three intramolecular

163 2 activation loop, as measured by changes in carboxyl group labeling, required both dimerization and

164 tem, such as the biphenyl system, and a free carboxyl group leads to highly potent and selective GIVA

165 The presence of three equally reactive carboxyl groups leads to FTR modifications through react

166 C) is a heptapeptide with an aspartate alpha-carboxyl group linked to AMP via phosphoramidate bond.

167 robial biomass, possessing a high density of carboxyl groups may be a mechanism by which ordered dolo

168 es formed in enzymatic reactions involved in carboxyl group metabolism.

169 The amplification effect of carboxyl group modified Fe(3)O(4) MNPs of two sizes on S

170 iwalled carbon nanotubes functionalized with carboxyl groups (MWCNTf) was developed to modify glassy

171 the active site of OASS, and its C-terminal carboxyl group occupies the same anion binding pocket as

172 ved structure, this residue interacts with a carboxyl group of 3-hydroxyglutarate, the hydrolysis pro

173 Compound 5b was prepared by coupling the carboxyl group of 3b and the free amino group of arylate

174 )-catalyzed amide bond formation between the carboxyl group of 5caC and a primary amine group.

175 ealing specific hydrogen bonds between the 5-carboxyl group of 5caC and the conserved epi-DNA recogni

176 These findings showed that loss of the carboxyl group of a C18 monounsaturated fatty acid lead

177 residue is enzymatically linked to the gamma-carboxyl group of a glutamate in the primary sequence of

178 on requires a direct interaction between the carboxyl group of allosteric effectors and Arg-120 of Ea

179 amino group of free glutamate and the gamma-carboxyl group of an active-site glutamate in SidE.

180 stance, 2.71A; angle, 100 degrees ) with the carboxyl group of Asp79.

181 nto the corresponding 1,3-dioxolanes and the carboxyl group of benzoate ester into an orthoester func

182 d GXGRXG motif is shown to interact with the carboxyl group of biotin and to stabilise the alpha- and

183 ich coordinate the same oxygen atom of the 4-carboxyl group of CAIR; whereas, the third coordinates t

184 units are formed by attaching glycine to one carboxyl group of cis-1,2-cyclohexanedicarboxylic acid (

185 Although interactions with the carboxyl group of GABA remain unknown, three positively

186 positioned to bestow specificity for the 6''-carboxyl group of GlcNAc(3NH(2))A through a salt bridge.

187 he structure of the L38E variant, the buried carboxyl group of Glu38 interacts with two backbone amid

188 nocoumarin (DECM) was used to cage the gamma-carboxyl group of glutamic acid, which is also a neurotr

189 The alpha-carboxyl group of glycine was covalently coupled to the

190 d to the mineral surface but bonded with the carboxyl group of glyphosate.

191 Unexpectedly, the carboxyl group of H148D is found in a buried position, d

192 rived from the deprotonation of the terminal carboxyl group of MHA).

193 ) was observed, probably stabilized by the 5-carboxyl group of OG, not reported before.

194 a trans double bond introduced close to the carboxyl group of palmitic acid, which is specifically e

195 From this, it can be concluded that the carboxyl group of PEP is responsible for energetic coupl

196 le-strand DNA oligo was immobilized with the carboxyl group of poly(p-aminobenzoic acid) and served a

197 rved enzyme that methyl esterifies the alpha carboxyl group of prenylated proteins including Ras and

198 rgies of binding one solvent molecule to the carboxyl group of SA.

199 Carboxyl group of syn-isomers may also participate in th

200 a hydrogen bond with the oxygen atom of the carboxyl group of the amino acid attached to the A-site

201 The carboxyl group of the bound asparagine makes salt bridge

202 d acid, the initial addition of water to the carboxyl group of the indolecarboxylic acid leads to a h

203 The preferred site for amidation is the free carboxyl group of the meso-diaminopimelic acid residue.

204 The carboxyl group of the substrate was bound by Arg(265) an

205 Replacing the carboxyl group of the substrate with a methyl alcohol or

206 rough a phosphoramidate linkage to the alpha-carboxyl group of the terminal aspartate.

207 nother amino acid, or even blocking the free carboxyl group of this arginine residue by amidation, el

208 The carboxyl group of this compound is required in a particu

209 The carboxyl group of this segment was coupled to the N-term

210 se A catalyzes the amide linkage between the carboxyl group of threonine and the amino group of penta

211 ms an amide bond between the BcpA C-terminal carboxyl group of threonine and the side-chain amino gro

212 e and asparagine of the NPQTN motif, and the carboxyl group of threonine is amide-linked to the amino

213 the threonine and glycine residues, and the carboxyl group of threonine is amide-linked to the side

214 and the alanine (A) residue; the C-terminal carboxyl group of threonine is subsequently amide linked

215 Dtx3L/Parp9 ADP-ribosylates the carboxyl group of Ub Gly76.

216 enefited from the reactive functional groups-carboxyl groups of Alb NPs, p19 protein, a viral protein

217 Carboxyl groups of amino acids are reduced to iodomethyl

218 with a few of 10 negatively charged sulfo or carboxyl groups of Arixtra at the interfaces.

219 oups in proteins with the lowest pKs are the carboxyl groups of aspartic acid side-chains.

220 mutants revealed that catalysis requires the carboxyl groups of Glu362 and Asp426, and not of Asp383,

221 the substrate is primarily anchored by gamma-carboxyl groups of Glu57 and Glu208 at the DOHH active s

222 s-linking by blocking the solvent-accessible carboxyl groups of horseradish peroxidase and alkaline p

223 groups of N-terminal residues but also gamma-carboxyl groups of internal (non-N-terminal) Asp and Glu

224 Using EDC and Sulfo-NHS, terminal carboxyl groups of N-succinyl-Ala-Ala-Pro-Phe p-nitroani

225 ains through the coordination bonds with the carboxyl groups of PAA blocks.

226 The carboxyl groups of PAA brushes can act as reducing moiet

227 tably trapped within the PAA brushes and the carboxyl groups of PAA can serve as internal proton sour

228 covalently conjugated ICG-NH2 to the pendant carboxyl groups of poly (ethylene glycol)-block-poly(2-m

229 se-catalyzed flux of (13)C label between the carboxyl groups of pyruvate and lactate in the tumor can

230 ering the binding sites to interact with the carboxyl groups of templates, were imbedded into MIPs by

231 cium-driven electrostatic interactions among carboxyl groups of the AGPs and the pectic acids give ri

232 To be specific, the richness of carboxyl groups of the CDs enabled strong adsorption of

233 n binding assays indicated that the retained carboxyl groups of the fatty acids helped maintain a tig

234 The ligands of the metal ion are the carboxyl groups of the first and third Asp residues of t

235 The carboxyl groups of the PAA graft could be derivatized to

236 ment (coccolith vesicle) through the charged carboxyl groups of their uronic acid residues.

237 ell as from the neutralization of the native carboxyl groups of thin-film composite polyamide membran

238 It is found that both the ammonium and carboxyl groups offer good water binding sites with bind

239 sol side-chain cleavage by reducing the C-20 carboxyl group on cortisol, yielding 20beta-dihydrocorti

240 cetyl-l-ornithine (PALAO) indicates that the carboxyl group on Lys302 forms a strong hydrogen bonding

241 We also show that the carboxyl group on nonreducing end glucuronic acid in dod

242 eractions between active site residues and a carboxyl group on the Pchlide molecule result in a polar

243 this study demonstrate that the presence of carboxyl groups on ENPs and divalent ions in the solutio

244 elimination of calcium bridging between the carboxyl groups on MWNTs and silanol groups on silica su

245 f stoichiometric Pdr-Pdx complexes only when carboxyl groups on Pdx were activated.

246 analogues bearing hydroxyl, amino, amido, or carboxyl groups on the azabicyclic ring.

247 via diimide-activated amidation between the carboxyl groups on the CNT surface and amine groups on t

248 -1,2-ethandiyl (PCBS), resulting in terminal carboxyl groups on the LPG-ISAM.

249 w protons to gain access to and leave buried carboxyl groups on the proteolipid subunits (c, c', and

250 , Pro, and His differ, as does the number of carboxyl groups on the respective surfaces, whereas the

251 Electrochemically formed carboxyl groups on the surface of the graphite were cros

252 The carboxyl groups on the surface of the modified barley st

253 ca-coated UCNPs (50 nm in diameter) exposing carboxyl groups on the surface were conjugated to a seco

254 to host up to three water molecules and the carboxyl group one water molecule before additional wate

255 In contrast, ligands containing carboxyl groups only, such as succinate and propionate,

256 stalled by cyclization of the pentenoic acid carboxyl group onto the vinyl epoxide in an S(N)2' fashi

257 substrate for lactonization, by allowing the carboxyl group oxygen to approach more closely the methy

258 yl-aliphatic ketones, aliphatic and aromatic carboxyl groups, phenol, and methoxy phenyl ethers.

259 nalized polystyrene nanospheres with surface carboxyl groups (PPs and QPs, respectively) were fabrica

260 d symmetric, and asymmetric vibration of the carboxyl group present in the ciprofloxacin.

261 latform for the DNA-c by the large number of carboxyl groups present on the functionalized gold nanop

262 t a LPMO (from Neurospora crassa) introduces carboxyl groups primarily in surface-exposed crystalline

263 nique Zn2+ coordination via two thiols and a carboxyl group provides selective binding of the activat

264 ly bound to MBs functionalized with amine or carboxyl groups, respectively.

265 lysis suggests that mechanisms involving two carboxyl groups result in the most stable bond to the mi

266 e of a gamma-ketone relative to the terminal carboxyl group resulted in C-C bond cleavages along the

267 nucleophilic attack on the phosphorus by the carboxyl group resulting in the spontaneous elimination

268 nors), followed by surface modification with carboxyl-group-rich polymers.

269 Exposed carboxyl groups seem to favor the direct route of elimin

270 Similarly, the BE of carboxyl groups shifted approximately -1.3 eV upon depro

271 The pK(a)s of the carboxyl groups studied vary significantly but all are l

272 provided a high content of surface confined carboxyl groups suitable for direct covalent binding of

273 ks) involve binding to two oxygen atoms from carboxyl groups (the most superficial binding peak) or t

274 ce of a receptor to bind the C-terminal free carboxyl group, the C-terminal amidated group, or the N-

275 are complexed and dewatered by surface-bound carboxyl groups, thus decreasing the energy required for

276 iate involves early proton transfer from the carboxyl group to water along with C-C bond cleavage, pr

277 of Asp383, confirming the enzyme employs two carboxyl groups to degrade lippopolysaccharide using an

278 CNTs used in our studies were derivatized by carboxyl groups to facilitate their dispersion in water.

279 such as the N terminus; (ii) converting the carboxyl groups to the active ester of N-hydroxysuccinim

280 al enzymes carry out metabolically important carboxyl group transfer reactions and are potential targ

281 Helix stabilization requires the protonated carboxyl group; unexpectedly, this stabilization could n

282 was efficiently converted into the required carboxyl group via conventional transformations.

283 e systems, and in these, the position of the carboxyl group was extended from the ligand core, either

284 A water-soluble conjugate (1) with intact carboxyl groups was prepared by addition of poly(ethylen

285 The terminal carboxyl groups were covalently conjugated to monoclonal

286 roparticles functionalized homogenously with carboxyl groups were generated using stop-flow lithograp

287 Qdots with exposed carboxyl groups were readily taken up by synaptic vesicl

288 These carboxyl groups were utilized to achieve variable degree

289 purpose as the proton can be carried on the carboxyl group, whereas the basicity of the tropylium io

290 leobase recognition involving the C-terminal carboxyl group, which is only required in the reverse re

291 luorescein diacetate, still possesses a free carboxyl group whose ionization constant is such that th

292 Other derivatives with modification of the 5-carboxyl group with an ester group or with a thiourea-ba

293 cine buffer molecule which interacts via its carboxyl group with conserved active site residues S130,

294 A derivatives obtained by conjugation of its carboxyl group with different alpha-amino acids.

295 he pilin C terminus, the blocking of the Ser carboxyl group with the addition of an Ala prevented gly

296 Through reaction of the carboxyl groups with (+)-biotinyl-3,6,9,-trioxaundecaned

297 Cloaking its carboxyl groups with a hydrophobic moiety is shown to en

298 Observations support the deprotonation of carboxyl groups with low acid dissociation constants (pK

299 ng domain has an unusually high affinity for carboxyl groups, with KD at approximately 100 microM.

300 suggest that the pK values for these buried carboxyl groups would be greater than 8 in the absence o